Teachware
Metrohm AG
CH-9101 Herisau
teachware@metrohm.com
This documentation is protected by copyright. All rights reserved.
Although all the information given in this documentation has been checked
with great care, errors cannot be entirely excluded. Should you notice any
mistakes please send us your comments using the address given above.
Documentation in additional languages can be found on http://prod-
ucts.metrohm.com under Literature/Technical documentation.
Figure 3Attaching the exchange unit ............................................................. 9
Figure 4Contact pins for the exchange unit .................................................. 11
Table of figures
805 Dosimat
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1 Introduction
The 805 Dosimat is a versatile dosing drive which can be used with a number
of different Metrohm devices (e.g. Titrando or sample changer). The 805
Dosimat and the corresponding 806 Exchange Unit are suitable as a buret
not only for simply dosing auxiliary solutions but also for titrations.
1.1 Instrument description
Thanks to various 806 Exchange Units with 1, 5, 10, 20 or 50 mL dosing
cylinders, the 805 Dosimat is suitable for flexible use as a buret (dosing unit
and drive). Older exchange units (without data chip) can also be used.
The exchange units can be set up on the Dosimat and also removed again
in one easy manual step.
1 Introduction
1.2 About the documentation
Caution
Please read through this documentation carefully before putting the
instrument into operation. The documentation contains information and
warnings which the user must follow in order to ensure safe operation of
the instrument.
1.2.1 Symbols and conventions
The following symbols and styles are used in this documentation:
Cross-reference to figure legend
The first number refers to the figure number, the second to the instrument part in the figure.
Instruction step
Carry out these steps in the sequence shown.
Warning
805 Dosimat
This symbol draws attention to a possible life hazard
or risk of injury.
Warning
This symbol draws attention to a possible hazard due
to electrical current.
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1.3 Safety instructions
1.3 Safety instructions
1.3.1 General notes on safety
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Warning
This symbol draws attention to a possible hazard due
to heat or hot instrument parts.
Warning
This symbol draws attention to a possible biological
hazard.
Caution
This symbol draws attention to a possible damage of
instruments or instrument parts.
Note
This symbol marks additional information and tips.
This instrument may only be operated in accordance with the specifications in this documentation.
This instrument has left the factory in a flawless state in terms of technical
safety. To maintain this state and ensure non-hazardous operation of the
instrument, the following instructions must be observed carefully.
1.3.2 Electrical safety
The electrical safety when working with the instrument is ensured as part of
the international standard IEC 61010.
Only personnel qualified by Metrohm are authorized to carry out service
work on electronic components.
Warning
Warning
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805 Dosimat
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1 Introduction
Warning
Never open the housing of the instrument. The instrument could be damaged by this. There is also a risk of serious injury if live components are
touched.
There are no parts inside the housing which can be serviced or replaced
by the user.
Protection against electrostatic charges
Warning
Electronic components are sensitive to electrostatic charges and can be
destroyed by discharges.
Always pull the mains cable out of the mains connection socket before
connecting or disconnecting electrical appliances on the rear panel of the
instrument.
1.3.3 Working with liquids
Caution
Periodically check all system connections for leaks. Observe the relevant
regulations in respect to working with flammable and/or toxic fluids and
their disposal.
1.3.4 Flammable solvents and chemicals
Warning
All relevant safety measures are to be observed when working with flammable solvents and chemicals.
■Set up the instrument in a well-ventilated location (e.g. laboratory
flue).
■Keep all sources of flame far from the workplace.
■Clean up spilled fluids and solids immediately.
■Follow the safety instructions of the chemical manufacturer.
805 Dosimat
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1.3 Safety instructions
1.3.5 Recycling and disposal
This product is covered by European Directive 2002/96/EC, WEEE – Waste
from Electrical and Electronic Equipment.
The correct disposal of your old equipment will help to prevent negative
effects on the environment and public health.
More details about the disposal of your old equipment can be obtained from
your local authorities, from waste disposal companies or from your local
dealer.
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805 Dosimat
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805 Dosimat
On
Status
1
2
3
4
6
5
Metrohm
2 Overview of the instrument
2 Overview of the instrument
Figure 1Front 805 Dosimat
Guide openings
1
For centering the exchange unit
Contact pins
3
For the data chip
LED "On"
5
Lights up when the Titrando and a controller
(Touch Control or computer) are connected
to the mains and switched on.
Piston rod
2
Moves the piston of the exchange unit up and
down.
Coupling
4
For switching the flat stopcock
LED "Status"
6
Indicates the current status of the internal
dosing drive
805 Dosimat
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Nr
Made by Metrohm
Herisau Switzerland
1
2
Figure 2Rear 805 Dosimat
Type plate
1
Contains specifications concerning mains
voltage, instrument type and serial number.
Connection cable
2
For connecting to a control device.
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805 Dosimat
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3 Installation
3.1 Setting up the instrument
3.1.1 Packaging
The instrument is supplied in highly protective special packaging together
with the separately packed accessories. Keep this packaging, as only this
ensures safe transportation of the instrument.
3.1.2 Checks
Immediately after receipt, check whether the shipment has arrived complete
and without damage by comparing it with the delivery note.
3.1.3 Location
The instrument has been developed for operation indoors and may not be
used in explosive environments.
3 Installation
Place the instrument in a location of the laboratory suitable for operation
and free of vibrations, if possible protected from corrosive atmospheres and
contamination by chemicals.
The instrument should be protected against excessive temperature fluctuations and direct sunlight.
3.2 Connecting the 805 Dosimat
Note
In the case of a Titrando with exchange unit, the MSB Port 1 is used by
the internal drive. The MSB 1 is therefore not available for an 805 Dosimat .
The 805 Dosimat is controlled by devices which are equipped with a 'Metrohm Serial Bus' (MSB). These are e.g. Titrandos or sample changers.
Connect the 805 Dosimat on the rear of the corresponding device to one
of the connectors (MSB 1/MSB 2 to MSB 4 ). The 805 Dosimat can how-
ever not be connected to devices with an MSB connector which do not
support tandem dosing.
805 Dosimat
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3.2 Connecting the 805 Dosimat
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Warning
Connect the 805 Dosimat only to control devices which have been
switched off beforehand. The control device will only be able to recognize
the Dosimat during the switch-on sequence.
Observe the alignment of the connection socket. Never use excessive
force to plug in the connection cable! Doing so could damage the device
electronics.
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805 Dosimat
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4 Working with the exchange unit
The 806 exchange unit has an integrated data chip which allows to save
data for the exchange unit and for the reagent. The data is being edited in
the Touch Control or in the PC software. The assembly of the exchange unit
is described in the manual for the 806 exchange unit.
4 Working with the exchange unit
805 Dosimat
Figure 3Attaching the exchange unit
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To attach the exchange unit, proceed as follows:
Slide the exchange unit from the front onto the 805 Dosimat and push
1
all the way to the rear, so that it snaps in and the LED Status flashes
slowly.
It must snap in audibly.
If the exchange unit is attached correctly, its initialization is being activated
by a micro switch which is triggered by the guide bolts of the exchange unit.
The exchange unit is being recognized and the data is being read automatically from the data chip. After this, the LED Status lights up constantly.
The following table provides an overview showing all operating states of the
internal dosing device which are indicated with the LED Status:
LED Status
Operating status of the dosing
device
offNo exchange unit is attached.
flashes constantlyThe Titrando is ready to dose or
titrate. The exchange unit has been
attached correctly and recognized
and is now in the exchange position, i.e. the exchange unit can be
removed.
flashes slowlyThe Titrando is dosing or filling or
the exchange unit is not in the
exchange position, respectively.
An 806 intelligent exchange unit
has been attached and the data on
the integrated data chip is being
read or written.
flashes fastError at the dosing drive (see Chap.
5)
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805 Dosimat
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5 Handling and maintenance
5.1 General information
5.1.1 Care
The 805 Dosimat requires no special care. Take care to ensure however that
it is not exposed to any excessive contamination nor to any corrosive influences. These could under certain circumstances result in functional disruptions and a reduction in the service life of the inherently sturdy mechanics
and electronics.
Monthly inspections are called for in the event that alkali, corrosive or highconcentration reagents are used. If non-problematic reagents are used, then
the inspection intervals can be extended to between six and twelve months.
Spilled chemicals and solvents should be removed immediately. Above all,
the plug connection on the rear of the instrument should be protected from
contamination.
5 Handling and maintenance
Caution
Although this is extensively prevented by design measures, the mains plug
of the control device should be unplugged immediately if aggressive
media has penetrated the inside of the instrument, so as to avoid serious
damage to the instrument electronics. In such cases, the Metrohm Service
must be informed.
Figure 4Contact pins for the exchange unit
Contact pins
1
For exchanging data with the exchange unit.
The contact pins for data exchange with the data chip are made of titanium
and are exceptionally resistant to both chemicals and abrasion.
805 Dosimat
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5.2 Quality Management and validation with Metrohm
Caution
Take care to ensure that the contact pins do not become contaminated.
Wipe off any contaminations at once.
In the event of more serious contamination, you can use a moist cloth
(possibly with a small amount of dishwashing detergent or ethanol).
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5.1.2 Maintenance by Metrohm Service
Maintenance of the 805 Dosimat is best carried out as part of an annual
service, which is performed by specialist personnel of the Metrohm company. If working frequently with caustic and corrosive chemicals, a shorter
maintenance interval could be necessary.
The Metrohm service department offers every form of technical advice for
maintenance and service of all Metrohm instruments.
5.2 Quality Management and validation with Metrohm
Quality Management
Metrohm offers you comprehensive support in implementing quality management measures for instruments and software. Further information on
this can be found in the brochure «Quality Management withMetrohm» available from your local Metrohm agent.
Validation
Please contact your local Metrohm agent for support in validating instruments and software. Here you can also obtain validation documentation to
provide help for carrying out the Installation Qualification (IQ) and the
Operational Qualification (OQ). IQ and OQ are also offered as a service
by the Metrohm agents. In addition, various application bulletins are also
available on the subject, which also contain Standard Operating Proce-dures (SOP) for testing analytical measuring instruments for reproducibility
and correctness.
Maintenance
Electronic and mechanical functional groups in Metrohm instruments can
and should be checked as part of regular maintenance by specialist personnel from Metrohm. Please ask your local Metrohm agent regarding the
precise terms and conditions involved in concluding a corresponding maintenance agreement.
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805 Dosimat
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You can find information on the subjects of quality management, validation and maintenance as well as an overview of the documents currently
available at www.metrohm.com/com/ under Support.
5.3 GLP - Validation
Every Dosimat and every exchange unit manufactured by the Metrohm
company is subjected to rigorous quality controls prior to shipment. Every
exchange unit is issued a quality certificate attesting conformance with the
quality criteria of Metrohm. GLP (Good Laboratory Practice) requires,
among other things, periodic inspection of analytical measuring devices with
respect to precision and correctness on the basis of standard operating procedures Standard Operating Procedure, SOP). This may also include an
inspection of dosing accuracy.
5 Handling and maintenance
Note
Recommended literature
■Metrohm brochure "Quality management with Metrohm", detailed infor-
mation concerning the principles and procedural methods of Good
Laboratory Practice
■Metrohm Applications Bulletin 283/1 Validation of Metrohm burets
The validation of burets is carried out by the Metrohm service with special
software.
The Metrohm agents worldwide offer the possibility of on-site inspections
and certifications of Dosimats and exchange units with respect to accuracy.
It is recommended that an accuracy inspection be performed when the dosing cylinders and dosing pistons of an exchange unit are replaced .
805 Dosimat
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6.1 Problems
6 Troubleshooting
6.1 Problems
ProblemCauseRemedy
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Data of the exchange
unit cannot be read.
Dosimat cannot be
actuated by the control device.
Exchange unit recognized either not at all
or incorrectly.
LED "Status" is flashing fast.
Data chip mechanically
damaged or impaired by
chemicals.
Connection between Dosimat and control device is
interrupted or an error has
occurred on the Dosimat.
The exchange unit has not
correctly been attached.
The dosing drive is overloaded because the flat stopcock is blocked.
■Remove the exchange unit and set it up
again.
■Have the data chip replaced by the Metrohm
Service Dept.
■Check the cable connections.
■Switch the instrument off and on again.
■Check the dosing and filling rate.
■Contact the Metrohm Service Dept.
■Remove the exchange unit and set it up
again.
■Check the correct placing of the exchange
unit.
■Check the piston and flat stopcock position.
■Switch the instrument off and on again.
■If necessary contact the Metrohm Service
Dept.
Switch off the Touch Control or exit PC Control.
Check wether the exchange unit can be
removed. If it cannot be removed, check wether
the flat stopcock still can be turned. Switch it
manually to the exchange position turning it to
the right (see manual for the exchange unit).
Remove the exchange unit and proceed as
described in the manual for the exchange unit.
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The dosing drive is overloaded because the piston is
blocked.This error is displayed by the software
(Touch Control or PC Control / tiamo).
Switch the control device off and then on again.
The dosing device is being initialized during
switching on. Remove the exchange unit and
clean it as described in the manual for the
exchange unit in chapter "Care and maintenance". Contact the Metrohm service if removing the exchange unit is not possible.
805 Dosimat
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ProblemCauseRemedy
6 Troubleshooting
LED "Status" is not
illuminated although
an exchange unit is
attached.
No dosing takes
place at all.
The data of the exchange
unit cannot be read
because the data chip has
been damaged mechanically or by chemicals.
The exchange unit has not
correctly been attached.
Tubing connections are
blocked or the exchange
unit is not assembled correctly.
Have the data chip being replaced by the
Metrohm service.Until the data chip is being
replaced you can remove the data chip yourself
in order to be able to still use the exchange unit.
The cylinder volume is automatically recognized
nevertheless, but no data can be read from the
exchange unit or be saved on it anymore.
Remove the exchange unit and attach it again
until it snaps in. The LED flashes during data is
read from an intelligent exchange unit (806) and
lights up constantly if the exchange unit has correctly been recognized.
■Check whether the tubings are correctly con-
nected.
■Check whether the dosing tip is blocked.
■Check whether the filling tubing is blocked.
■Check whether all of the openings of the
bottle attachment have accidentally been
closed (vacuum in the supply bottle!). One of
the openings must be open as a pressure
compensation or has to be equipped with an
(open) adsorber tube.
■Remove the exchange unit and check
whether the dosing piston is connected to
the drive.
The entire system is
blocked.
The exchange unit
cannot be attached
to the Dosimat.
The exchange unit
cannot be attached.
805 Dosimat
An exceptional error has
occurred on the Dosimat or
the control device.
The dosing piston is misaligned.
The piston rod of the
exchange unit is misaligned.
The flat stopcock of the
exchange unit is not in the
exchange position.
The piston rod in the
exchange unit is not in the
right position.
■Check the cable connections.
■Switch the instrument off and on again.
Carefully pull out or push in the piston with the
6.2739.010 key until the recess of the piston rod
is tight on the buret base.
Switch the instrument off and on again.
Switch the flat stopcock manually to the
exchange position (lever switch directed to the
right).
Switch the piston rod to the right position (see
manual for the exchange unit).
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6.1 Problems
ProblemCauseRemedy
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The exchange unit
cannot be removed
and the LED "Status"
is flashing slowly.
The exchange unit
cannot be removed
from the Dosimat.
The flat stopcock is
blocked.
It is being dosed or filled
and/or the Dosimat is not in
the exchange position.
Piston and/or flat stopcock
are not in filling position.
The flat stopcock is contaminated, corroded or worn
out.
Stop the run or carry out a "filling".
■Carry out the [Filling] on the control device.
Check the cable connections to the control
instrument.
■Switch the instrument off and on again.
■Carefully loosen the flat stopcock out of its
holder and switch the control device off and
on again.
■Put the flat stopcock into water with a small
amount of dishwashing detergent or into
ethanol and eventually clean it with ultrasonic. Rinse it thoroughly and place it again
into the flat stopcock holder.
■Replace the defectous flat stopcock.
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805 Dosimat
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7 Appendix
7.1 Buret data
The 806 Exchange Unit is equipped with a data chip which contains the
specifications for the dosing unit, the tubing connections and the reagent
used.
Indications on dosing unit / tubing connections
■Order number of the dosing unit
■Serial number of the dosing unit
■Serial number of the dosing cylinder
■Length and diameter of the tubings on the dosing ports
■Validation date
Indications on the reagent
■Name of the reagent
■Titer of the reagent
■Concentration of the reagent
■Production and expiry date of the reagent
7 Appendix
The 805 Dosimat makes it possible to read and overwrite data with the aid
of a suitable device (e.g. Titrando). Consult the respective manual in order
to determine whether the Metrohm device which you are using is capable
of accomplishing this.
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8.1 Dosing drive
8 Technical specifications
8.1 Dosing drive
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Cylinder volume of
1 ml, 5 ml, 10 ml, 20 ml or 50 ml
the dosing unit
Resolution
Dosing / filling time
20'000 steps per cylinder volume
18 seconds each for the cylinder volume
8.2 Power supply
from control
device
Dosing device connector
±12 V, 5 V , 6 W
Mini DIN plug, 8-pin, (MSB)
8.3 Safety specifications
Design and testing
■EN/IEC 61010-1:2001
■UL 61010-1: 2004
■CSA-C22.2 No. 61010-1: 2004
■Degree of protection IP40
■Protection class III
Safety instructions
The documentation contains safety instructions which have to be followed by the user in order to ensure safe operation of the instrument.
This is to certify the conformity to the standard specifications for electrical
appliances and accessories, as well as to the standard specifications for
security and to system validation issued by the manufacturing company.
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Name of commodity
Electromagnetic compatibility
Safety specifications
805 Dosimat
Microprocessor-controlled dosing device for liquid-handling purposes in
laboratories.
This instrument has been built and has undergone final type testing according to the standards:
EN/IEC 61010-1: 2001, UL 61010-1: 2004,
CSA-C22.2 No. 61010-1: 2004, protection class I
Manufacturer
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This instrument meets the requirements of the CE mark as contained in the
EU directives 2006/95/EC (LVD), 2004/108/EC (EMC). It fulfils the following
specifications:
EN 61326-1Electrical equipment for measurement, control and
laboratory use – EMC requirements
EN 61010-1Safety requirements for electrical equipment for
measurement, control and laboratory use
Metrohm Ltd., CH-9101 Herisau/Switzerland
Metrohm Ltd. is holder of the SQS certificate ISO 9001:2000 Quality management system for development, production and sales of instruments and
accessories for ion analysis.
805 Dosimat
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9 Conformity and warranty
Herisau, 6 January, 2009
D. Strohm
Vice President, Head of R&D
9.2 Quality Management Principles
Metrohm Ltd. holds the ISO 9001:2000 Certificate, registration number
10872-02, issued by SQS (Swiss Association for Quality and Management
Systems). Internal and external audits are carried out periodically to assure
that the standards defined by Metrohm’s QM Manual are maintained.
The steps involved in the design, manufacture and servicing of instruments
are fully documented and the resulting reports are archived for ten years.
The development of software for PCs and instruments is also duly documented and the documents and source codes are archived. Both remain the
possession of Metrohm. A non-disclosure agreement may be asked to be
provided by those requiring access to them.
The implementation of the ISO 9001:2000 quality management system is
described in Metrohm’s QM Manual, which comprises detailed instructions
on the following fields of activity:
Instrument development
The organization of the instrument design, its planning and the intermediate
controls are fully documented and traceable. Laboratory testing accompanies all phases of instrument development.
A. Dellenbach
Head of Quality Management
805 Dosimat
Software development
Software development occurs in terms of the software life cycle. Tests are
performed to detect programming errors and to assess the program’s functionality in a laboratory environment.
Components
All components used in the Metrohm instruments have to satisfy the quality
standards that are defined and implemented for our products. Suppliers of
components are audited by Metrohm as the need arises.
Manufacture
The measures put into practice in the production of our instruments guarantee a constant quality standard. Production planning and manufacturing
procedures, maintenance of production means and testing of components,
intermediate and finished products are prescribed.
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9.3 Warranty (guarantee)
Customer support and service
Customer support involves all phases of instrument acquisition and use by
the customer, i.e. consulting to define the adequate equipment for the analytical problem at hand, delivery of the equipment, user manuals, training,
after-sales service and processing of customer complaints. The Metrohm
service organization is equipped to support customers in implementing
standards such as GLP, GMP, ISO 900X, in performing Operational Qualification and Performance Verification of the system components or in carrying
out the System Validation for the quantitative determination of a substance
in a given matrix.
9.3 Warranty (guarantee)
Metrohm guarantees that the deliveries and services it provides are free from
material, design or manufacturing errors. The warranty period is 36 months
from the day of delivery; for day and night operation it is 18 months. The
warranty remains valid on condition that the service is provided by an
authorized Metrohm service organization.
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Glass breakage is excluded from the warranty for electrodes and other
glassware. The warranty for the accuracy corresponds to the technical specifications given in this manual. For components from third parties that make
up a considerable part of our instrument, the manufacturer's warranty provisions apply. Warranty claims cannot be pursued if the Customer has not
complied with the obligations to make payment on time.
During the warranty period Metrohm undertakes, at its own choice, to either
repair at its own premises, free of charge, any instruments that can be shown
to be faulty or to replace them. Transport costs are to the Customer's
account.
Faults arising from circumstances that are not the responsibility of Metrohm,
such as improper storage or improper use, etc. are expressly excluded from
the warranty.
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10 Accessories
10.1 Scope of delivery
Note
Subject to change without notice.
10.1.1 805 Dosimat 2.805.0010
Qty.Order no.Description
11.805.0010805 Dosimat
10 Accessories
16.2739.010Wrench
For exchange units.
Length (mm):190
18.805.8001ENManual 805 Dosimat
805 Dosimat
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10.2 Optional accessories
10.2 Optional accessories
10.2.1 805 Dosimat 2.805.0010
Order no.Description
6.2151.010Cable MSB plug / socket
Extension cable for MSB connections and for Touch Control - Titrando. Mini DIN
socket - Mini DIN plug
Length (m):2
6.3026.110Exchange unit 1 mL
Exchange unit with integrated data chip with 1 mL glass cylinder and light protection. PCTFE/PTFE flat stopcock, FEP tubing connection, antidiffusion buret tip
and standard amber glass reagent bottle.
Volume (mL):1
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6.3026.150Exchange unit 5 mL
Exchange unit with integrated data chip with 5 mL glass cylinder and light protection. PCTFE/PTFE flat stopcock, FEP tubing connection, antidiffusion buret tip
and standard amber glass reagent bottle.
Volume (mL):5
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805 Dosimat
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Order no.Description
6.3026.210Exchange unit 10 mL
Exchange unit with integrated data chip with 10 mL glass cylinder and light protection. PCTFE/PTFE flat stopcock, FEP tubing connection, antidiffusion buret tip
and standard amber glass reagent bottle.
Volume (mL):10
6.3026.220Exchange unit 20 mL
Exchange unit with integrated data chip with 20 mL glass cylinder and light protection. PCTFE/PTFE flat stopcock, FEP tubing connection, antidiffusion buret tip
and standard amber glass reagent bottle.
Volume (mL):20
10 Accessories
6.3026.250Exchange unit 50 mL
Exchange unit with integrated data chip with 50 mL glass cylinder and light protection. PCTFE/PTFE flat stopcock, FEP tubing connection, antidiffusion buret tip
and standard amber glass reagent bottle.
Volume (mL):50
805 Dosimat
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Index
Index
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A
Accuracy .................................. 13
B
Buret data ................................ 17
C
Certification ............................. 13
Connection cable ....................... 6
Contact pins ......................... 5, 11
Control ....................................... 7
Coupling .................................... 5
D
Data chip ........................... 15, 17
Data exchange ......................... 17
Device type ................................ 6
Dosing accuracy ....................... 13
E
Electromagnetic compatibility ... 18
Electrostatic charge .................... 3
Emission ................................... 18
Exchange unit .......... 9, 15, 16, 15
F
Flat stopcock blocked ............... 14
G
GLP .................................... 12, 13
Good Laboratory Practice ......... 13
Guarantee ................................ 22
Guide openings .......................... 5
I
Immunity .................................. 18
L
LED
On ....................................... 5
Status ........... 5, 10, 15, 16, 14
M
Maintenance ............................ 11
O
Order number .......................... 17
P
Piston blocked .......................... 14
Piston rod ................................... 5
Power supply ............................ 18
Production date ........................ 17
Q
Quality certificate ..................... 13
Quality control ......................... 13
Quality Management ................ 12
R
Reagent
Concentration .................... 17
Expiry date ......................... 17
Name ................................. 17
Production date .................. 17
Titer ................................... 17
S
Safety instructions ...................... 2
Safety specifications ................. 18
Serial number ....................... 6, 17
Service ....................................... 2
Service Agreement ................... 12
SOP .......................................... 13
T
Tubing diameter ....................... 17
Tubing length ........................... 17
V
Validation ........................... 12, 13
Validation date ......................... 17
W
Warranty .................................. 22
■■■■■■■■
26
805 Dosimat
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