Metrohm 788IC User Manual
788 IC Filtration Sample Processor
METROHM AG
CH-9101 Herisau
Switzerland
DES FUSIBLES DE 250V
USE ONLY WITH 250V
100-120V
UNIQUEMENT AVEC
FUSES/EMPLOYER
Metrohm
Metrohm
MetrohmMetrohm
220-240V
Instructions for Use
8.788.1003
CH-9101 Herisau/Switzerland
Phone +41 71 353 85 85
Fax +41 71 353 89 01
E-Mail info@metrohm.com
Internet www.metrohm.com
788 IC Filtration Sample Processor
Instructions for Use
8.788.1003 03.2001 / up, dö
Table of contents
Table of contents
1 Introduction
1.1 Instrument description ................................................................... 1
1.2 Parts and controls........................................................................... 2
1.3 Information about the Instructions for Use................................. 5
1.3.1 Organization........................................................................... 5
1.3.2 Notation and pictograms ....................................................... 6
1.4 Support dokumentation.................................................................. 7
1.4.1 Application Bulletins............................................................... 7
1.4.2 Application Notes................................................................... 7
1.5 Safety Notes ..................................................................................... 7
1.5.1 Electrical Safety...................................................................... 7
1.5.2 General safety rules ............................................................... 8
2 Installation
2.1 Setting up the instrument ..............................................................9
2.1.1 Packaging ..............................................................................9
2.1.2 Check ..................................................................................... 9
2.1.3 Location.................................................................................. 9
2.1.4 Arrangement of the instruments............................................. 9
.....................................................................................
........................................................................................
1
9
2.2 Mains connection ..........................................................................10
2.2.1 Setting the mains voltage..................................................... 10
2.2.2 Fuses.................................................................................... 11
2.2.3 Mains cable and mains connection ..................................... 11
2.2.4 Switching the instrument on/off............................................ 11
2.3 Attaching the accessories ...........................................................12
2.3.1 Connecting the swing head .................................................12
2.3.2 Connecting the keyboard..................................................... 12
2.3.3 Installing the plug cover ....................................................... 12
2.3.4 Installing the splash protection ............................................ 13
2.3.5 Installing the needle or tubing.............................................. 13
2.3.6 Placing the sample rack....................................................... 14
2.3.7 Adjusting the sample rack.................................................... 14
2.3.8 Assembling the ultra-filtration cell ........................................ 16
2.3.9 Tubing connections.............................................................. 19
2.3.10 Tubing connections 788 – 754 Dialysis Unit ...................... 22
2.3.11 Fixing tubing and cables.................................................... 22
788 IC Filtration Sample Processor
I
Table of contents
2.4 Installation for full control with «IC Net»................................... 23
2.4.1 Connection options.............................................................. 23
2.4.2 General information on interface connections..................... 24
2.4.3 Metrohm IC Systems ........................................................... 25
2.4.4 MIC 1 – Modular anion or cation system
with electronic suppression.................................. 26
2.4.5 MIC 2 Modular anion system
with chemical suppression ................................... 27
2.4.6 MIC 3 Modular anion and cation system
with chemical suppression .................................. 28
2.4.7 MIC 7 Modular anion system
with chemical suppression and dialysis .............. 30
2.5 Installation with compact IC systems........................................ 34
2.5.1 Connection to 761 Compact IC or 790 Personal IC ............ 34
2.6 Installation for simple remote control of the IC system.......... 37
2.6.1 IC system without suppression............................................ 38
2.6.2 IC system with suppression with 788 as "Master"................ 38
2.6.3 IC system with suppression with PC as "Master"................. 39
2.6.4 IC system for simultaneous anion/cation determination...... 39
2.6.5 IC system with sample dialysis............................................ 40
2.7 Connection of devices to the RS232 interface ......................... 41
2.7.1 General information on RS232 interface.............................. 41
2.7.2 Connecting a printer ............................................................ 42
3 Operating tutorial
3.1 Prerequisites / Preparations........................................................ 45
3.2 Configuration................................................................................. 46
3.3 Rack configuration........................................................................ 47
3.4 Methods .......................................................................................... 49
3.5 "Tracing" ......................................................................................... 49
....................................................................
45
II
788 IC Filtration Sample Processor
Table of contents
4 Operation
4.1 Fundamentals of operation..........................................................53
4.1.1 Display.................................................................................. 53
4.1.2 Keyboard.............................................................................. 54
4.1.3 Overview of key functions .................................................... 55
4.1.4 Instrument dialog ................................................................. 64
4.1.5 Data entry............................................................................. 66
4.1.6 Text entry.............................................................................. 67
4.2 Basic settings ................................................................................69
4.2.1 Configuration – <CONFIG> key .........................................69
4.2.2 Locking keyboard functions ................................................. 73
4.3 Methoden ........................................................................................ 75
4.3.1 Structure of a method .......................................................... 75
4.3.2 Method parameters – <PARAM> key................................. 76
4.3.3 Programming of sequences................................................. 78
4.3.4 LEARN mode........................................................................ 79
4.3.5 TRACE funktion .................................................................... 79
4.3.6 Commands for sequences................................................... 80
4.3.7 Process control .................................................................... 85
4.3.8 User defined methods.......................................................... 86
4.3.9 POWERUP method .............................................................. 87
.........................................................................................
53
4.4 Manual operation...........................................................................88
4.4.1 Turning the sample rack / Positioning the samples............. 88
4.4.2 Moving the lift ....................................................................... 88
4.4.3 Setting the sample position.................................................. 89
4.4.4 Pump control........................................................................ 89
4.4.5 Display interface signals ......................................................89
4.4.6 Interface control ................................................................... 90
4.4.7 Print out reports.................................................................... 91
4.5 Sample racks.................................................................................. 93
4.5.1 Standard rack (6.2041.430).................................................. 93
4.5.2 Magnetic code ..................................................................... 93
4.5.3 Rack data ............................................................................. 94
4.5.4 Special beakers.................................................................... 96
4.6 Standard methods......................................................................... 97
4.6.1 Method "PC" and "PC Seg"................................................... 99
4.6.2 Method "SP" and "SP Seg".................................................. 100
4.6.3 Method "761" and "761 Seg"............................................... 101
4.6.4 Method "An Cat" and "AnCatSeg"....................................... 102
4.6.5 Method "Preconc"............................................................... 104
4.6.6 Method "Dialysis"................................................................ 106
4.7 Filtration........................................................................................108
4.6.1 Selecting suitable sample types ........................................ 108
4.6.2 Filtration membrane life...................................................... 108
4.6.3 Selecting a suitable filtration membrane............................ 109
788 IC Filtration Sample Processor
III
Table of contents
5 Interfaces
5.1 Remote interface ......................................................................... 111
5.1.1 Pin assignment of the remote socket .................................111
5.1.2 Functional characteristics ...................................................112
5.2 RS232 interface ........................................................................... 115
5.2.1 General rules for remote control .........................................115
5.2.2 Call-up of objects................................................................116
5.2.3 Trigger.................................................................................117
5.2.4 Status messages ................................................................118
5.2.5 Error messages...................................................................119
5.2.6 Remote control commands ................................................120
5.2.7 Data transmission protocol.................................................127
5.2.8 Handshake..........................................................................128
5.2.9 Pin assignment ...................................................................131
5.2.10 RS232 error rectification....................................................132
6 Appendix
6.1 Error messages ........................................................................... 133
....................................................................................
.......................................................................................
111
133
6.2 Technical data ............................................................................. 135
6.3 Maintenance and servicing........................................................ 137
6.3.1 Maintenance by Metrohm service.......................................137
6.3.2 Care of the unit ...................................................................137
6.3.3 Replacing the pump tubing ................................................138
6.3.4 Replacing the filtration membrane......................................139
6.4 Diagnosis...................................................................................... 141
6.4.1 General Information ............................................................141
6.4.2 Preparing the instrument ....................................................142
6.4.3 Working memory (RAM)......................................................143
6.4.4 Display ................................................................................143
6.4.5 Keyboard ............................................................................144
6.4.6 Remote interface.................................................................145
6.4.7 RS232 interface...................................................................146
6.4.8 External Bus interface .........................................................146
6.4.9 Beeper ................................................................................147
6.4.10 Rack code recognition......................................................147
6.5 Initialize data memory ................................................................ 148
6.6 Validierung / GLP ........................................................................ 150
IV
6.7 Warranty and conformity ........................................................... 151
6.7.1 Warranty..............................................................................151
6.7.2 EU Declaration of conformity..............................................152
6.7.3 Certificate of conformity and system validation..................153
6.8 Standard equipment ................................................................... 154
6.9 Optional accessories.................................................................. 157
6.10 Index............................................................................................ 159
788 IC Filtration Sample Processor
Table of contents
List of figures
Fig. 1
: Side view of the 788 IC Filtration Sample Processor ........................................2
Fig. 2
: Rear of the 788 IC Filtration Sample Processor ................................................4
: Setting the mains voltage ................................................................................ 10
Fig. 3
Fig. 4
: Keyboard connection ......................................................................................12
Fig. 5
: Installing the splash protection........................................................................13
: Needle installation ...........................................................................................14
Fig. 6
Fig. 7
: Sample rack placing........................................................................................14
Fig. 8
: Adjusting the sample rack .............................................................................15
Fig. 9
: Assembling the ultra-filtration cell....................................................................16
Fig. 10
: Installing the pump tubing ...............................................................................19
Fig. 11
: Mount ultra-filtration cell...................................................................................20
Fig. 12
: Opening chain links .........................................................................................22
Fig. 13
: Interconnection with anion or cation IC system
with electronic suppression (MIC 1) ................................................................26
Fig. 14
: Interconnection with anion IC system
with chemical suppression (MIC 2) ................................................................. 27
Fig. 15
: Interconnection with the combined anion and cation IC system
with chemical suppression (MIC 3) ................................................................. 28
Fig. 16
: Interconnection with anion IC system
with chemical suppression and dialysis (MIC 7).............................................30
Fig. 17
: Interconnection of with compact IC systems ..................................................34
Fig. 18
:
Interconnection with IC system without suppression..........................
Fig. 19:
Fig. 20
Fig. 21
Fig. 22
Fig. 23
Fig. 24
Fig. 25
Interconnection with IC system with suppression with 788 as "Master"
: Interconnection with IC system with suppression with PC as "Master"
:
Interconnection for anion/cation system.............................................
:
Interconnection with IC system with dialysis.......................................
: Connection possibilities for the RS232 interface ............................................41
: Schematic representation of the instrument dialog .......................................65
: Installation of the preconcentration column ..................................................104
.......
........
38
38
39
39
40
788 IC Filtration Sample Processor
V
Table of contents
VI
788 IC Filtration Sample Processor
1.1 Instrument description
1 Introduction
1.1 Instrument description
788 IC Filtration Sample Processor
The
ion chromatographic determinations including in-line filtration, especially in combination with Metrohm IC system instruments. It is possible
to apply and automate existing procedures for sample preparation using the ultra-filtration of the 788 IC Filtration Sample Processor.
The 127 sample tubes with a volume of 11 mL are arranged on the
sample rack in three rows, which guarantees easy access and unrestricted programming. Two additional rinsing positions allow sample introduction free from cross-contamination even with widely varying sample matrices. Sample tubes made of polypropylene are standard. To
protect the samples from external contamination, the tubes can be
hermetically sealed.
can be used for automating
Sample filtration and introduction to the injector is achieved by means
of its integrated double-channel peristaltic pump. The sample is conveyed by one channel of the pump through the ultra-filtration cell passing the membrane. At the same time the filtrate is aspirated off from the
rear of this membrane and transferred to the sample loop by the second channel of the pump. A PEEK needle for sealed or a PEEK tube for
open sample tubes can be used alternatively.
The sequences for the processing of each sample are freely definable
within broad boundaries. The same is true for the start and final sequences that are executed once either before or at the end of a sample
series. With the help of the LEARN mode, which is provided for creating
process methods, methods can be created easily and stored as user
methods.
Preprogrammed standard methods for the most common modes of
operation allow to use the 788 IC Filtration Sample Processor directly,
with only little programming effort. The time frame can be given by the
788 IC Filtration Sample Processor; alternatively, the whole sequence
can be managed by the «IC Net» remote control software via the
«
Queue» (sample table). The RS232 interface built in as standard allows remote control of the 788 IC Filtration Sample Processor from a
PC.
788 IC Filtration Sample Processor
1
1 Introduction
1.2 Parts and controls
4444
3333
2222
1111
Always install splash
protection!
55556
67
66
78
77
89
88
9
99
10
10
1010
11
11
1111
12
12
1212
13
13
1313
14
14
1414
15
15
1515
16
16
1616
17
17
1717
18
18
1818
19
19
1919
6666
20
20
2020
12
12
1212
21
21
2121
22
22
2222
23
23
2323
24
24
2424
25
25
2525
22
22
2222
36
36
3636
35
35
3535
34
34
3434
33
33
3333
32
32
3232
DES FU SI B LE S D E 25 0V
100-120V
USE ONLY WITH 250V
UNIQUEMENT AVEC
FUSES/EMPLOYER
Metrohm
Metrohm
MetrohmMetrohm
Fig. 1
: Side view of the 788 IC Filtration Sample Processor
220-240V
Always install plug cover!
22
22
2222
26
26
2626
27
27
2727
28
28
2828
29
29
2929
30
30
3030
31
31
3131
788 IC Filtration Sample Processor
2
1.2 Parts and controls
Splash protection (6.2751.040)
1111
Must be installed always in operation!
Needle
2222
PEEK needle (6.1835.010) or
PEEK tubing (6.1835.020)
Lift
3333
4444
5555 PEEK compression fitting
6666
7777
8888
With swing head attached
Needle guide (4.766.4330)
Attached (part of needle holder
(6.2833.000))
(4.766.4320)
PEEK compression fitting
(6.2744.010)
PTFE capillaries 1/16 "
Swing head
Attached
PTFE capillary (6.1803.070)
(0.97 mm / 0.40 m) Connection
needle – pump tubing
For PEEK needle or tubing
For connection of PEEK or
19
19 PEEK coupling (6.2744.030)
1919
Connecting compression fitting and
pump tubing
20
20 PEEK capillary (6.1831.060)
2020
For conveying the filtrate into the
sample loop
21
21 PTFE capillary (6.1803.050)
2121
(0.5 mm / 0.2 m) Connecting ultrafiltration cell and filtrate pump tubing
22
22 PVDF compression fitting
2222
(6.2744.000)
ies (6.1803.0X0) to ultra-filtration cell
23
23 Ultra-filtration cell (6.2729.110)
2323
(Plexiglass)
24
24 PTFE capillary (6.1803.060)
2424
(0.97 mm / 0.2 m) Connecting sample
pump tubing and ultra-filtration cell
25
25 PTFE capillary (6.1803.080)
2525
(0.97 mm / 1 m) Connecting ultrafiltration cell and waste
26
26 Cell holder
2626
For ultra-filtration cell
Connecting PTFE capillar-
(Olive)
(1 m)
Guide chain
9999
For fixing tubings and cables
10
10 Pump tubing (6.1826.070)
1010
(yellow/yellow) Conveying the sample
to the ultra-filtration cell
11
11 Pump tubing (6.1826.030)
1111
(orange/yellow) Conveying the filtrate
to the sample loop
Screw thread for splash protection 30
12
12
1212
Mounting pin
13
13
1313
For attaching the tubing cartridges
Tubing cartridge (6.2755.000)
14
14
1414
For pump tubing (6.1826.0X0)
Pump drive
15
15
1515
Roller head with contact rollers
Snap-action lever
16
16
1616
For releasing the tubing cartridge
Holding clamp
17
17
1717
For locking the tubing cartridge into
place
27
27 Tower
2727
28
28 PE bottle (6.1608.080)
2828
Connection cable for swing head
29
29
2929
Attached, incl. branch plug for remote
connection
30 Remote connection
3030
For additional Metrohm instruments
31
31 Plug cover (6.2752.010)
3131
32
32 Fuse holder
3232
Changing the fuses, see
33
33 Mains connection plug
3333
Mains connection, see
34
34 Mains switch
3434
For switching the instrument on/off:
I = ON 0 = OFF
Sample rack (6.2041.430)
35
35
3535
(300 mL)
section 2.2.2
section 2.2.3
18
18 Contact pressure lever
1818
For adjusting the contact pressure
788 IC Filtration Sample Processor
PP sample tube (6.2743.050) (11 mL)
36
36
3636
Can be sealed with 6.2743.070 PP caps
3
1 Introduction
9999
37
37
3737
14
14
1414
37
37
3737
27
27
2727
1111
37
37
37
37
3737
23
23
2323
3737
36
36
3636
26
26
2626
28
28
2828
35
35
3535
31
31
3131
: Rear of the 788 IC Filtration Sample Processor
Fig. 2
Splash protection (6.2751.040)
1111
Must be installed always in operation!
Guide chain
9999
For fixing tubings and cables
Type 1.788.
RS 232 Keyboard
Made by Metro hm Herisau Swi tzerland
35
35 Sample rack 6.2041.430
3535
36
36 PP sample tube (6.2743.050) (11 mL)
3636
Can be sealed with 6.2743.070 PP caps
28
28
2828
38
38
3838
39
39
3939
40
40
4040
Tubing cartridges (6.2755.000)
14
14
1414
For 6.1826.0X0 pump tubing
Tower
27
27
2727
PE bottle (6.1608.080)
28
28
2828
Plug cover (6.2752.010)
31
31
3131
788 IC Filtration Sample Processor
4
(300 mL)
37
37 Mounting screws for splash protec-
3737
tion
38
38 Serial number
3838
39
39 Keyboard connection
3939
40
40 RS232 connection
4040
1.3 Information about the Instructions for Use
1.3 Information about the Instructions for Use
Please read through these Instructions for Use carefully before
operating the 788 IC Filtration Sample Processor. The Instructions for
Use contain information and warnings to which the user must pay
attention in order to assure safe operation of the instrument..
1.3.1 Organization
These
ple Processor provide a comprehensive overview of the installation,
startup procedure, operation, fault rectification and technical specifications of this instrument. The Instructions for Use are organized as follows:
8.788.1003 Instructions for Use
Section 1 Introduction
Description of the instrument, parts and controls,
safety notes
Section 2 Installation
Mains connection, attachment of accessories,
connection to IC systems
Section 3 Operating tutorial
Introduction to the operation
Section 4 Operation
Detailed description of display, keyboard, methods,
manual operation, sample racks, standard methods,
and filtration
Section 5 Interfaces
Remote interface, RS232 interface and
remote control language
for the 788 IC Filtration Sam-
788 IC Filtration Sample Processor
Section 6 Appendix
Error messages, technical data, maintenance
and servicing, diagnosis, warranty, declaration
of conformity, standard equipment, optional
accessories, index
To find the information you require about the instruments please use either the
Quick Reference Guide
daily use as it explains the most important parameters and key functions.
Table of contents
is suitable for use as a reference work for
or the
Index
at the back. The
8.788.1013
5
1 Introduction
1.3.2 Notation and pictograms
The following notations and pictograms (symbols) are used in these
Instructions for Use:
<PUMP>
15
15
1515
89
89
8989
26
26
2626
'Bereich'
******** counter 0/127
PUMP- ready
Switch or key
Part or control of 788
Part or control of 732/733
Part or control of 754
Parameter or entry value
at 788 IC Filtration Sample
Processor
Display
Text in keyboard display of 788
IC Filtration Sample Processor
Hazard
This symbol draws attention to
a possible danger to life or
injury if the associated
directions are not followed
correctly.
Warning
This symbol draws attention to
possible damage to instruments or instrument parts if the
associated directions are not
followed correctly.
Caution
This symbol marks important
information. Read these directions before continuing.
Comment
This symbol marks additional
information and tips.
788 IC Filtration Sample Processor
6
1.4 Support documentation
1.4 Support documentation
1.4.1 Application Bulletins
The «Application Bulletin» is a collection of analytical methods, application examples and literature references. All these Application Bulletins
are available on request free of charge from your Metrohm supplier.
You will find an updated list of the Application Bulletins at any time under «http://www.metrohm.com».
1.4.2 Application Notes
The «Application Notes» present application information in concentrated form, i.e. on maximum 2 pages. You can order these free of
charge from your Metrohm supplier or view them in the Internet under
«
http://www.metrohm.com» and copy them from there.
1.5 Safety notes
1.5.1 Electrical safety
While electrical safety in the handling of the 788 IC Filtration Sample
Processor is assured in the context of the specifications IEC 1010-1
(protection class I), the following points should be noted:
x
Mains connection
Set the mains voltage and check the mains fuse and mains
connection in accordance with the instructions in section 2.2.
x
Opening the 788 IC Filtration Sample Processor
To avoid all danger of coming into contact with live components do
not open the instrument or remove any parts when the 788 IC Filtration
Sample Processor is connected to the power supply. Always disconnect the instrument from all voltage sources before you open it and
ensure that the mains cable is disconnected from mains con-
nection 33
33 !
3333
x
788 IC Filtration Sample Processor
Protection against static charges
Electronic components are sensitive to static charging and can be
destroyed by discharges. Before you touch any of the components
inside the 788 IC Filtration Sample Processor, you should earth
yourself and any tools you are using by touching an earthed object
(e.g. housing of the instrument or a radiator) to eliminate any static
charges which exist.
7
1 Introduction
1.5.2 General safety rules
x
Install splash protection
To avoid any danger of injury by the needle, the splash protection
must always be installed when operating the 788 IC Filtration Sample
Processor!
x
Install plug cover
To prevent any contamination of the mains and remote connection by
spilled solvents or chemicals, the plug cover must always be installed
when operating the 788 IC Filtration Sample Processor!
x
Do not use caps together with the PEEK tube
If you are using the 6.1835.020 PEEK tube, the sample tubes may not
be sealed with caps because they cannot be pierced by the PEEK
tubing and the tubing may be damaged thereby.
x
Handling of solvents
Check the pump tubing and all input and output leads periodically for
possible leaks. Follow the relevant instructions regarding the handling
of flammable and/or toxic solvents and their disposal.
x
Regular exchange of pump tubings
Pump tubings constitute consumable material and must be replaced
from time to time (see section 6.3.3). Suitable measures must be
taken so that any leak which might occur in the pump tubing or
connections during unattended operation will cause no damage
(collection device for any liquid which may leak out).
788 IC Filtration Sample Processor
8
2.1 Setting up the instrument
2 Installation
2.1 Setting up the instrument
2.1.1 Packaging
The 788 IC Filtration Sample Processor is supplied together with the
separately packed accessories in special packaging containing shockabsorbing foam linings designed to provide excellent protection. The
actual instrument is packed in an evacuated polyethylene bag to
prevent the ingress of dust. Please store all these special packagings
as only they can assure damage-free transport of the instrument.
2.1.2 Check
After receipt, immediately check whether the shipment is complete and
undamaged (compare with delivery note and list of accessories in
section 6.8
section 6.7.1
). In the case of transport damage, see instructions in
"Warranty".
2.1.3 Location
Position the instrument in the laboratory at a location convenient for
operation, free from vibrations and protected against a corrosive
atmosphere and contamination by chemicals.
Do not operate the 788 IC Filtration Sample Processor without splash
protection 1111 and plug cover 31
31 being installed!
3131
2.1.4 Arrangement of the instruments
788 IC Filtration Sample Processor
To make the connection for conveying the sample filtrate to the injection
valve at the 733 IC Separation Center (or 761 Compact IC or 790
20
Personal IC) with the peek capillary
the 788 IC Filtration Sample Processor immediately on the left side of
the IC system.
Take precautions to ensure that any leaks from pump tubings or
connections cannot cause more damage.
20
(length 1 m) supplied, position
2020
9
2 Installation
2.2 Mains connection
Follow the instructions below for connecting to the power supply. If
the instrument is operated with the mains voltage set wrongly and/or
wrong mains fuse there is a danger of fire!
2.2.1 Setting the mains voltage
34
34
3434
33
33
3333
32
32
3232
100 – 120 V
Before switching on the 788 IC Filtration Sample Processor for the first
time, check that the mains voltage set on the instrument (see
matches the local mains voltage. If not
instrument as follows:
1 Disconnect mains cable
220 -
--
- 240 V
--
- 120 V
100 -
220 – 240 V
32
Fuse holder
100 -
--
- 120 V
--
- 240 V
220 -
323232
33
33 Mains connection
3333
plug
34
34 Mains switch
3434
: Setting the mains voltage
Fig. 3
, reset the mains voltage on the
Disconnect mains cable from mains connection plug
788 IC Filtration Sample Processor.
33
33
of the
3333
Fig. 3
)
2 Remove fuse holder
32
Using a screwdriver, loosen fuse holder
32
beside the mains
3232
connection and take out completely.
3 Check fuse
Carefully take the fuse installed for the desired mains voltage out
of fuse holder and check its specifications (the position of the
fuse in the fuse holder is marked by the white arrow imprinted
next to the mains voltage range):
100}}}}120 V 0.5 A (slow-blow)
220}}}}240 V 0.25 A (slow-blow)
788 IC Filtration Sample Processor
10
Metrohm-Nr. U.600.0013
Metrohm-Nr. U.600.0010
2.2 Mains connection
4 Insert fuse
32
Change fuse if necessary and reinsert in fuse holder
32
3232
.
5 Install fuse holder
32
Depending on the desired mains voltage, insert fuse holder
32
3232
in
the 788 IC Filtration Sample Processor so that the corresponding
mains voltage range can be read normally and the adjacent
white arrow points to the white bar imprinted on the right side of
the fuse holder (see
Fig. 3
).
2.2.2 Fuses
One of the two fuses 0.5 A/slow-blow for 100}120 V or 0.25 A/slow-
32
blow for 220}240 V is installed in fuse holder
Sample Processor as standard.
32
of the 788 IC Filtration
3232
Ensure that the instrument is never put into operation with fuses of
another type, otherwise there is danger of fire!
For checking or changing fuses, proceed as described in
2.2.3 Mains cable and mains connection
Mains cable
The instrument is supplied with one of three mains cables
x
6.2122.020 with plug SEV 12 (Switzerland, })
x
6.2122.040 with plug CEE(7), VII (Germany, })
x
6.2133.070 with plug NEMA 5-15 (USA, })
which are three-cored and fitted with a plug with an earthing pin. If a
different plug has to be fitted, the yellow/green lead (IEC standard)
must be connected to protective earth (protection class I).
Any break in the earthing inside or outside the instrument can make it
a hazard!
Mains connection
Plug the mains cable into mains connection plug
Filtration Sample Processor (see
Fig. 3
).
section 2.2.1
33
33
of the 788 IC
3333
.
2.2.4 Switching the instrument on/off
The 788 IC Filtration Sample Processor is switched on and off using
34
mains switch
788 IC Filtration Sample Processor
34
3434
.
11
2 Installation
2.3 Attaching the accessories
For attaching the accessories at the 788 IC Filtration Sample
Processor, proceed in the order described below.
2.3.1 Connecting the swing head
29
Plug in the branch plug of the connection cable
attached to the swing head into the remote connection socket at the
788 IC Filtration Sample Processor and screw it onto this connection
using a screw-driver (see
2.3.2 Connecting the keyboard
Fig. 1
).
29
permanently
29 29
1
Connecting the keyboard
Connect the 6.2142.010 keyboard
to the keyboard connection
"Keyboard". For disconnection,
press the plug together slightly on
both sides.
2
Switch on instrument
Switch on the 788 IC Filtration
Sample Processor with mains
34
switch
lights up. The instrument is
initialized and the lift is raised
completely.
34
. The keyboard display
3434
2.3.3 Installing the plug cover
39
39
3939
Fig. 4
: Keyboard connection
To prevent any contamination of the mains and remote connection by
spilled solvents or chemicals, the 6.2752.010 plug cover must always
be installed when operating the 788 IC Filtration Sample Processor!
31
Install the plug cover
mains connection plug
Fig. 2
).
788 IC Filtration Sample Processor
12
31
in the corresponding guide groove above
3131
33
33
and remote connection
3333
30
30
3030
(see
Fig. 1
and
2.3 Attaching the accessories
2.3.4 Installing the splash protection
To avoid any danger of injury by the needle, the 6.2751.040 splash
protection must always be installed when operating the 788 IC
Filtration Sample Processor!
1 Remove holding screws
37
Remove the holding screws
12
screw threads
2 Remove protective film from splash protection
Remove the plastic film glued on both sides of the splash
protection
3 Install splash protection
Attach splash protection onto the screw threads at the tower and
fix it with the holding screws and the washer using the
6.2621.100 Allen key.
12
at tower
1212
1111
.
37
and the washer mounted on the
3737
27
27
using the 6.2621.100 Allen key.
2727
1111 Splash protection
(6.2751.040)
37
Holding screws
373737
2.3.5 Installing the needle or tubing
1 Remove PEEK compression fitting 5
Remove PEEK compression fitting
holder
2 Insert needle
Insert needle
tubing) completely into the opening of the needle holder
4444
.
2222
(6.1835.010) PEEK needle or 6.1835.020 PEEK
: Installing the splash protection
Fig. 5
5555
screwed onto the needle
37
37
3737
1111
37
37
3737
4444
.
788 IC Filtration Sample Processor
3 Fix needle or tubing
Tighten compression fitting
use tools!).
(never
5555
in needle holder
4444
by hand
13
2 Installation
2222 PEEK needle (6.1835.010) or
PEEK tubing (6.1835.020)
4444 Needle holder
5555 PEEK compression fitting
(4.766.4320)
6666 PEEK compression fitting
(6.2744.010)
7777 Swing head
8888 PTFE capillary (6.1803.070)
If you are using the 6.1835.020 PEEK tubing, the sample tubes may
not be sealed with caps because they cannot be pierced by the PEEK
tubing and the needle may be damaged thereby.
2.3.6 Placing the sample rack
8888
7777
6666
5555
4444
2222
Fig. 6
: Needle installation
1
Place sample rack
Place sample rack
turntable of the 788 IC Filtration
Sample Processor according
Fig. 7
to
2
Read magnetic code
Press <RESET> to move
the rack to the home position,
in which the magnetic code
can be read (details see
section 4.5
.
).
2.3.7 Adjusting the sample rack
If a new sample rack is placed on the 788 IC Filtration Sample
Processor for the first time, it must be adjusted on a rack position in the
middle row (example: position 37) as follows:
35
35
on the
3535
Fig. 7
: Sample rack placing
1 Place sample rack
Place empty sample rack on the 788 IC Filtration Sample
Processor and press <RESET> (see
788 IC Filtration Sample Processor
14
section 2.3.6
).
2.3 Attaching the accessories
2222 PEEK needle (6.1835.010) or
2222
PEEK tubing (6.1835.020)
41
41
35
Sample rack (6.2041.430)
353535
41
Adjusting position 37
414141
42
Adjusting screw
424242
: Adjusting the sample rack
Fig. 8
2 Move to adjusting position
Press <MOVE>, enter number '37' and confirm with <ENTER>.
Sample rack and swing head are turned until needle is above
the adjusting position 37 (first opening of the middle row).
3 Check needle position
x
Press <
of the sample rack.
x
Check needle position: If the needle cannot be lowered
unhindered through the upper hole of the adjusting position,
continue directly with point 4.
x
Continue lowering the needle by pressing <
needle is ca. 1 cm above the lower level of the sample rack.
x
Check needle position: If the needle cannot be lowered
unhindered through the lower hole of the adjusting position,
continue directly with point 4.
x
Lower needle completely by pressing <
x
Check needle position: If the needle is in the middle of the
lower hole, the sample rack must not be adjusted (continue in
this case with point 5).
Ð
> until the needle is ca. 1 cm above the upper level
Ð
> until the
Ð
>.
4141
42
42
4242
35
35
3535
788 IC Filtration Sample Processor
4 Adjust sample rack
42
41
41
4141
42
on the lower level of the
4242
.
x
Loosen the three adjusting screws
sample rack using the 6.2621.100 Allen key.
x
Carefully turn the two upper levels of the sample rack by hand
until the lowered needle is exactly in the middle of the lower
hole at the adjusting position
x
Tighten the adjusting screws.
5 Move to rest position
Press <RESET> to move the sample rack to the rest position.
15
2 Installation
2.3.8 Assembling the ultra-filtration cell
In this section, the assembling of the ultra-filtration cell including the
filtration membrane is described. Please consider section 4.7 for
evaluating the membrane type and time of exchange. The exchange of
filtration membranes is also described in section 6.3.4.
23
23 43
2323
43 44
4343
44
4444
45
45 46
4545
46
4646
47
47
4747
Fig. 9
Ultra-filtration cell (6.2729.110)
23
23
2323
Top part of the ultra-filtration cell 47
43
43
4343
44
44 Sealing ring (E.301.0111) 48
4444
Bottom part of the ultra-
45
45
4545
filtration cell
Filtration membrane (6.2714.020)
50
50
5050
1 Prepare ultra-filtration cell
x
Extract ultra-filtration cell
the four dummy stoppers.
x
Using the 6.2621.070 Allen key, completely loosen the 5
screws
remove sealing ring
x
Thoroughly rinse the sealing ring, bottom part and top part of
the dialysis cell with ultrapure water.
: Assembling the ultra-filtration cell
46
46
, separate top part
4646
50
5050
46
46 Screws V.022.6030 incl.
4646
47 Outlet for sample filtrate
4747
Inlet for sample solution
48
4848
49
49 Outlet for sample solution
4949
44
44
4444
34
34
3434
.
48
48 49
4848
washer 4.754.4090
from its packaging and remove
43
43
from bottom part
4343
4950
4949
45
45
4545
and
788 IC Filtration Sample Processor
16
2.3 Attaching the accessories
Use only ultrapure water or ethanol to clean the dialysis cell;
organic solvents (e.g. acetone) will cause damage to the plexiglas
cell!
2 Prepare filtration membrane
x
Use the 6.2831.010 tweezers to extract a new filtration
50
membrane
50
(6.2714.020) from its packaging and immerse
5050
in a Petri dish containing ultra pure water for approx. 2 min
until the membrane is completely saturated with water.
Because the filtration membrane it is stretched out thereby, it has to
be watered before inserting into the ultra-filtration cell. Otherwise, the
membrane could be crumbled in the cell, which leads to blocking.
3 Insert filtration membrane
43
x
Lay top part
43
on a paper wipe with its inside facing
4343
upwards.
44
x
Insert sealing ring
x
Using the tweezers, place the wet dialysis membrane inside
44
in the appropriate recess in the top part.
4444
the sealing ring on the top part of the filtration cell.
Do not connect the dialysis cell with anything other than the
6.2744.000 PVDF compression fittings supplied. If 6.2744.010
PEEK compression fittings are used, stress cracks may appear in the
ultra-filtration cell !
4 Close ultra-filtration cell
43
46
46
46 46
43
.
4343
right
x
Insert sealing ring in the appropriate recess in top part
45
x
Place top part on bottom part
x
Using the 6.2621.070 Allen key, screw the 5 screws
45
so that both parts lie flush.
4545
in and tighten up.
5 Attach ultra-filtration cell
26
x
Insert the assembled ultra-filtration cell in the cell holder
26
26 26
according to Fig. 1 or Fig. 11. The heads of the five screws
46
46
fit to the small holes of the cell holder.
46 46
788 IC Filtration Sample Processor
17
2 Installation
6 Rinse ultra-filtration cell
x
Before rinsing the cell, please finish all tubing connections as
described in the following sections.
x
Every time the filtration membrane is changed, the remaining
air in the cell and tubings has to be removed. This can be
done by rinsing with ultrapure water.
x
A completely installed 788 IC Filtration Sample Processor with
ultra-filtration cell is required for processing the following
steps. The rinsing solution (e.g. ultrapure water) is stored in a
300 mL PE bottle on the special beaker position 1. The 788 IC
Filtration Sample Processor is online and in normal state. The
').
PUMP–'
) and the 788 is ready
pump is switched of (display: '
for use (display: '
x
Turn the sample rack to position the beaker with the rinsing
ready
solution under the needle by pressing <MOVE> followed by
choosing 's
pec.1
' with <SELECT>.
x
Lower the lift into rinse position with <LIFT> and <SELECT>
rinse
'
x
Turn on the pump by pressing <PUMP>. All connected
'
tubings and the ultra-filtration cell will be rinsed.
x
After adequate time (e.g. 5 min.), switch off the Pump
(<PUMP>) and raise the lift to its rest position by pressing
<HOME>.
788 IC Filtration Sample Processor
18
2.3 Attaching the accessories
2.3.9 Tubing connections
The tubing connections on the 788 IC Filtration Sample Processor and
the connection to the injection valve of the 733 IC Separation Center
must be made as follows:
Pump tubings are consumable material with a lifetime which depends
on the contact pressure (see chapter 6.3.3). This is why the tubing
cartridges should be raised completely by loosening snap-action lever
on the right-hand side if the pump is to remain switched off for a
16
16
1616
considerable length of time (the set contact pressure remains
unchanged).
The 6.1826.0X0 pump tubing is made of PVC and must not be used
for rinsing with solutions which contain acetone. In such cases, rinse
with different pump tubing or a different pump.
19
8/21
8/21
8/218/21
19 10/11
1919
10/11 43
10/1110/11
43 14
4343
14 18
1414
18 43
1818
43 19
16
16 66666666
4343
1616
19
1919
24/20
24/20
24/2024/20
Abb. 10
Line 1: Conveying the sample
to the ultra-filtration cell
8888 PTFE capillary (6.1803.070)
6666 PEEK compression fitting
(6.2744.010)
PEEK coupling (6.2744.030)
19
19
1919
10
10 Pump tubing (6.1826.070)
1010
43
43 Stopper (yellow/yellow)
4343
Tubing cartridge (6.2755.000)
14
14
1414
Contact pressure lever
18
18
1818
16
16 Snap-action lever
1616
PTFE capillary (6.1803.060)
24
24
2424
: Installing the pump tubing
Line 2: Conveying the filtrate
to the injection loop
21
21 PTFE capillary (6.1803.050)
2121
6666 PEEK compression fitting (6.2744.010)
19
19 PEEK coupling (6.2744.030)
1919
11
11 Pump tubing 6.1826.030
1111
43
43 Stopper (orange/yellow)
4343
14
14 Tubing cartridge (6.2755.000)
1414
18
18 Contact pressure lever
1818
16
16 Snap-action lever
1616
20
20 PEEK capillary (6.1831.060)
2020
788 IC Filtration Sample Processor
19
2 Installation
1 Install pump tubing
14
x
Release tubing cartridge
sing down snap-action lever
13
13
pin
on the 788 IC Filtration Sample Processor (see
1313
x
Press contact pressure lever
as far as it will go.
x
Insert pump tubings
shown in
the corresponding holder on the left-hand side of each tubing
cartridge.
x
Place both tubing cartridges on mounting pin
down on the right-hand side until snap-action lever
into position on holding clamp
formed in the pump tubing.
2 Connection needle – pump tubing 10
x
Mount a PEEK compression fitting
PTFE capillary
x
Screw the PTFE capillary
on to the PEEK compression fitting
needle holder
x
Insert PTFE capillary into the guide chain
section 2.3.10
x
Screw a coupling
the other end of the PTFE capillary.
x
Push coupling on to the inlet end of the pump tubing
(yellow/yellow, see
Fig. 10
4444
).
. The black-black stopper
8888
.
(see
19
19
1919
14
from holding clamp
1414
16
16
and remove from mounting
1616
18
18
on the tubing cartridge down
1818
10
10
1010
Fig. 6
on to the PEEK compression fitting
Fig. 10
11
11
and
in the tubing cartridges
1111
17
17
. Take care that no kinks are
1717
6666
on both ends of the
8888
with the PEEK compression fitting
5555
already mounted on
).
9999
).
17
17
by pres-
1717
43
43
must click into
4343
13
13
and press
1313
16
16
1616
Fig. 1
(see
10
10
1010
Fig. 1
13
13
1313
click
and
6666
).
as
at
6666 PEEK compression fitting
(6.2744.010)
10
10 Pump tubing (6.1826.070)
1010
Pump tubing 6.1826.030
11
11
1111
19
19 PEEK coupling (6.2744.030)
1919
21
21 PTFE capillary (6.1803.050)
2121
PVDF compression fitting
22
22
2222
(6.2744.000)
24
24 PTFE capillary (6.1803.060)
2424
PTFE capillary (6.1803.080)
25
25
2525
Cell holder
26
26
2626
Top part of the ultra-filtration cell
43
43
4343
45
45 Bottom part of the ultra-filtration cell
4545
Fig. 11
11
11
1111
10
10
1010
21
21
2121
19
19
1919
6666
22
22
2222
43
43
4343
45
45
4545
24
24
2424
22
22
2222
22
22
2222
25
25
2525
26
26
2626
: Mount ultra-filtration cell
788 IC Filtration Sample Processor
20
2.3 Attaching the accessories
Do not connect the dialysis cell with anything other than the
6.2744.000 PVDF compression fittings supplied. If 6.2744.010
PEEK compression fittings are used, stress cracks may appear in the
ultra-filtration cell !
3 Connection pump tubing 10 – ultra-filtration cell
x
Mount a PEEK compression fitting
24
capillary
x
Mount a PVDF compression fitting
PTFE capillary
x
Screw this PEEK capillary with the PVDF compression fitting
to inlet opening
x
Push coupling
(yellow/yellow) (see
24
and screw it on to coupling
24 24
24
24
.
2424
48
48
of the bottom part of the cell (see
4848
19
19
on to the outlet end of the pump tubing
1919
Fig. 10
).
6666
on the end of the PTFE
19
19
.
1919
22
22
on the other end of the
2222
Fig. 9
).
10
10
1010
4 Connection ultra-filtration cell – waste
22
x
Mount a PVDF compression fitting
25
capillary
x
Screw this end of the PTFE capillary with the PVDF
25
2525
.
compression fitting to outlet opening
the cell (see
x
Mount the other end of the PTFE capillary to a waste bottle
Fig. 9
).
22
on the end of the PTFE
2222
49
49
of the bottom part of
4949
(e.g. optional: 6.1608.070 bottle with 6.1602.150 siphon
GL45).
5 Connection ultra-filtration cell – pump tubing 11
x
Mount a PEEK compression fitting
21
capillary
x
Mount a PVDF compression fitting
PTFE capillary
x
Screw this PTFE capillary with the PVDF compression fitting
21
and screw it on to coupling
2121
21
21
.
2121
to outlet opening for the filtrate
Fig. 9
(see
x
Push coupling
(orange/yellow) (see
).
19
19
on to the inlet end of the pump tubing
1919
Fig. 10
).
6666
on the end of the PTFE
19
19
.
1919
22
22
on the other end of the
2222
47
47
of the top part of the cell
4747
11
11
1111
6 Connection pump tubing 11 – injection valve
(Underlined numbers are parts or controls from the Instructions
for Use for the 733 IC Separation Center)
(see
6666
on the end of the PEEK
19
19
.
1919
22
22
28
28
or
2828
.
of the
Fig. 14
2222
and
Fig. 15
x
Mount a PEEK compression fitting
20
capillary
x
Push coupling
(orange/yellow) (see
x
At the 733 IC Separation Center, loosen the rotary nipple
20
and screw it on to coupling
2020
19
19
on to the outlet end of the pump tubing
1919
Fig. 10
).
screwed onto the interior side of connection
84
x
Take PTFE suction tubing
84
8484
732/733 Instructions for Use) completely out of connection
66
28
28
and unscrew from connection "1" of injection valve
or
2828
66
6666
11
11
1111
22
22
2222
.
788 IC Filtration Sample Processor
21
2 Installation
20
x
Pull the PEEK capillary
the 733 IC Separation Center and screw onto connection "1"
of injection valve
6666
fitting
x
Retighten rotary nipple on the interior side of connection
or
7 Tubing connection injection valve – waste
x
Insert 6.2744.020 coupling (from 733 accessories) into
connection
x
Screw PTFE suction tubing
attached to connection
container.
In the case of the 733.0020 IC Separation Center with two injection
valves, it is possible to fill both sample loops from the same 788 IC
Filtration Sample Processor. For this, connection "1" of valve A (outlet
of the sample loop) must be connected to connection "2" of valve B
(inlet of the sample loop) using a 6.1803.040 PEEK capillary (15 cm).
.
28
28
to fix the capillary
2828
21
21
or
2121
20
through the opening
2020
66
66
using a 6.2744.010 PEEK compression
6666
20
20
.
2020
27
27
of the 733 IC Separation Center.
2727
84
84
onto the 6.2744.020 coupling
8484
27
27
21
21
or
and lead it into the waste
2727
2121
22
22
2222
or
28
28
2828
of
22
22
2222
2.3.10 Tubing connections 788 – 754 Dialysis Unit
If the 788 IC Filtration Sample Processor is used for an IC system with
sample dialysis (see
at the 754 Dialysis Unit is used for sample conveying instead of the
pump at the 788 IC Filtration Sample Processor. Additionally, the ultrafiltration cell is bridged. The tubing connections between the 754
Dialysis Unit and the 733 IC Separation Center have to be made as
shown in
the inlet of the sample, which is installed as follows:
Install a PEEK compression fitting 6.2744.010 on the inlet end of the
PTFE tubing
connected to the 754 Dialysis Unit and screw it on the PEEK
compression fitting
Fig. 8
26
26
2626
section 2.4.7 or section 2.5.8
of the
754 Instruction for Use
(6.1803.030, see
5555
(see
Fig. 6
).
Fig. 8 of the 754 Instruction for Use
. The only change concerns
2.3.11 Fixing tubing and cables
In order to fix tubing or cables in the
guide chain
opened with a screw driver or another
appropriate tool..
9999
any chain link may be
), the peristaltic pump
)
Fig. 12
788 IC Filtration Sample Processor
22
: Opening chain links
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