MINDRAY BS 300 Service Manual

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BS-300

Chemistry Analyzer

Service Manual

Intellectual Property Statement

SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD. (hereinafter called Mindray) owns the intellectual property rights to this Mindray product and this manual. This manual may refer to information protected by copyrights or patents and does not convey any license under the patent rights of Mindray, nor the rights of others. Mindray does not assume any liability arising out of any infringements of patents or other rights of third parties.

Mindray intends to maintain the contents of this manual as confidential information. Disclosure of the information in this manual in any manner whatsoever without the written permission of Mindray is strictly forbidden.

Release, amendment, reproduction, distribution, rent, adaption and translation of this manual in any manner whatsoever without the written permission of Mindray is strictly forbidden.

, , , , are the registered trademarks or trademarks owned by Mindray in China and other countries. All other trademarks that appear in this manual are used only for editorial purposes without the intention of improperly using them. They are the property of their respective owners.

Responsibility on the Manufacturer Party

Contents of this manual are subject to changes without prior notice. All information contained in this manual is believed to be correct. Mindray shall not

be liable for errors contained herein nor for incidental or consequential damages in connection with the furnishing, performance, or use of this manual.

Mindray is responsible for safety, reliability and performance of this product only in the condition that:

 all installation operations, expansions, changes, modifications and repairs of this

product are conducted by Mindray authorized personnel;

 the electrical installation of the relevant room complies with the applicable

national and local requirements;

 the product is used in accordance with the instructions for use.

WARNING:

It is important for the hospital or organization that employs this equipment to carry out a reasonable service/maintenance plan. Neglect of this may result in machine breakdown or injury of human health.

NOTE:

This equipment is to be operated only by medical professionals trained and authorized by Mindray or Mindray-authorized distributors.

Warranty

THIS WARRANTY IS EXCLUSIVE AND IS IN LIEU OF ALL OTHER WARRANTIES, EXPRESSED OR IMPLIED, INCLUDING WARRANTIES OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PURPOSE.

Exemptions

Mindray's obligation or liability under this warranty does not include any transportation or other charges or liability for direct, indirect or consequential damages or delay resulting from the improper use or application of the product or the use of parts or accessories not approved by Mindray or repairs by people other than Mindray authorized personnel.

This warranty shall not extend to:  any Mindray product which has been subjected to misuse, negligence or

accident;

 any Mindray product from which Mindray's original serial number tag or product

identification markings have been altered or removed;

 any product of any other manufacturer.

Return Policy

Return Procedure

In the event that it becomes necessary to return this product or part of this product to Mindray, the following procedure should be followed:

1 Obtain return authorization: Contact the Mindray Service Department and

obtain a Customer Service Authorization (Mindray) number. The Mindray number must appear on the outside of the shipping container. Returned shipments will not be accepted if the Mindray number is not clearly visible. Please provide the model number, serial number, and a brief description of the reason for return.

2 Freight policy: The customer is responsible for freight charges when this

product is shipped to Mindray for service (this includes customs charges).

3 Return address: Please send the part(s) or equipment to the address offered

by Customer Service department

Company Contact

Manufacture: Shenzhen Mindray Bio-Medical Electronics Co., Ltd. Address:

Phone: Fax:

Mindray Building, Keji 12th Road South, Hi-tech Industrial Park, Nanshan, Shenzhen, P.R.China, 518057

+86 755 26582479 26582888 +86 755 26582500 26582501

Preface

Who Should Read This Manual

This manual is written for service professionals authorized by Mindray.

Conventions Used in This Manual

Safety Symbols

This chart explains the symbols used in this manual.

When you see … Then …

WARNING:

Read the statement following the symbol. The statement is alerting you to an operating hazard that can cause personal injury.

BIOHAZARD:

CAUTION:

NOTE:

Read the statement following the symbol. The statement is alerting you to a potentially biohazardous condition.

Read the statement following the symbol. The statement is alerting you to a possibility of system damage or unreliable results.

Read the statement following the symbol. The statement is alerting you to information that requires your attention.

Graphics

All graphics, including screens and printout, are for illustration purpose only and must not be used for any other purposes.

Contents

Preface........................................................................................................................................... i

Who Should Read This Manual .............................................................................................. i

Conventions Used in This Manual .......................................................................................... i

1 Specifications....................................................................................................................1-1

1.1 System Feature...................................................................................................1-1

1.2 Loading System Feature .....................................................................................1-1

1.3 Analysis System Feature.....................................................................................1-2

1.4 Others..................................................................................................................1-2

2 System Installation...........................................................................................................2-1

2.1 Check before Installation.....................................................................................2-1

2.2 Installation Procedure..........................................................................................2-1

3 System Descriptions ........................................................................................................3-1

3.1 Dispensing System..............................................................................................3-1

3.1.1 Probe assemblies.................................................................................3-1

3.1.2 Disk assemblies ...................................................................................3-2

3.2 Feeder .................................................................................................................3-3

3.2.1 Feeder assemblies...............................................................................3-3

3.2.2 Manipulator...........................................................................................3-4

3.3 Temperature Control System...............................................................................3-5

3.3.1 Temperature control assembly.............................................................3-5

3.3.2 Reagent preheating..............................................................................3-6

3.3.3 Reagent refrigeration............................................................................3-7

3.4 Photometric System ............................................................................................3-8

3.5 Fluid System........................................................................................................3-8

3.6 ISE Module (optional)........................................................................................3-10

Functions of Boards.........................................................................................................4-1

4.1 Main Control Board..............................................................................................4-1

4.2 Power Drive Board ..............................................................................................4-2

4.3 A/D Conversion Board.........................................................................................4-2

4.4 Reagent Refrigeration Board...............................................................................4-2

4.5 Level Detection Boards .......................................................................................4-3

4.6 Feeder Connection Board ...................................................................................4-3

4.7 Manipulator Connection Board............................................................................4-3

4.8 Probes Connection Board ...................................................................................4-4

4.9 Power Supply Assembly......................................................................................4-4

5 Maintenance and Service.................................................................................................5-1

5.1 Replacing Light Filter Assembly ..........................................................................5-1

5.2 Replacing Optical Fiber.......................................................................................5-4

5.3 Adjusting Reaction Disk, Manipulator and Feeder..............................................5-7

5.4 Adjusting Probes and Disks.................................................................................5-8

5.5 Replacing Components of ISE Unit (optional)...................................................5-10

5.5.1 Replacing Tubing................................................................................5-10

5.5.2 Replacing Pumps...............................................................................5-13

5.5.3 Replacing ISE Module........................................................................5-13

6 Software Introduction.......................................................................................................6-1

Contents

6.1 System Software..................................................................................................6-1

6.1.1 System initialization..............................................................................6-1

6.1.2 Shutdown processing...........................................................................6-2

6.2 Control Software..................................................................................................6-2

7 Service Flow......................................................................................................................7-1

7.1 Fluid Level Detection Failure of Reagent Probe..................................................7-1

7.2 Fluid Level Detection Failure of Sample Probe...................................................7-2

7.3 Liquid Dropping From Probes..............................................................................7-3

7.4 Failing to Detect Level of Water for Washing Exteriors.......................................7-4

7.5 Abnormal Results................................................................................................7-5

7.5.1 All Results Being Abnormal..................................................................7-5

7.5.2 Some Results Being Abnormal.............................................................7-5

7.5.3 Several Results Being Abnormal..........................................................7-6

7.6 Insufficient Light Intensity of Lamp......................................................................7-7

7.7 Temperature Control Failure................................................................................7-8

7.8 Bar Code Scanner (optional) Failure...................................................................7-9

7.9 Feeder Failure ................................................................................................... 7-11

7.9.1 Transducer Distribution of the Feeder................................................7-11

7.9.2 Feeder Failure....................................................................................7-12

7.9.3 Manipulator Failure.............................................................................7-13

7.10 Troubleshooting of ISE Unit (optional)...............................................................7-13

8 Mechanical Structure .......................................................................................................8-1

9 Tools and Parts.................................................................................................................9-1

9.1 Service Tools .......................................................................................................9-1

9.2 Parts ....................................................................................................................9-1

Maintenance And Test Software....................................................................................10-1

General..............................................................................................................10-1

10.1

Command ..........................................................................................................10-3

10.2

10.2.1 Single Command Area.......................................................................10-3

10.2.2 Macroinstruction Area.......................................................................10-10

10.3 PARA and Speed.............................................................................................10-13

10.4 Temperature.....................................................................................................10-19

10.5 Photoelectric....................................................................................................10-20

Appendix A Board s Connection Diag rams.............................................................................. A-1

Appendix B Test Points of Boards............................................................................................ B-1

1 Specifications

1.1 System Feature

 Dimension: 980mm × 710mm × 1200mm (W × D × H)  Weight: 175kg  Power supply: AC100-130V ± 10% or 200-240V ± 10%  Input power: 1000VA  System: optional, multi-channel, multi-test  Scope: Clinical chemistries  Test types: end-point, kinetic and fixed-time. All support double-reagent and

double-wavelength

 Calibration type: Linear (single-point, two-point and multi-point), Logistic 4P,

Logistic 5P, Exponential 5P, Polynominal 5P, Parabola, Spline

 QC rules: Westgard multi-rule,

Twin-plot

 Tests analyzed simultaneously: 48 (single-reagent) / 24 (double-reagent); if the

ISE unit (optional) is connected, 3 (Na, K and Cl included) or 4 (Na, K, Cl and Li included) tests are added

 Throughput: maximum 300tests/h; if the ISE (optional) is connected, maximum

420tests/h (Na, K and Cl included) or maximum 480 tests/h (Na, K, Cl and Li included)

Specifications

−

-R, Cumulative sum check, Cumulative error,

1.2 Loading System Feature

 Sample volume: 3µl~45µl; Precision: 0.5µl; for the ISE (optional), 70µl serum,

70µl plasma, 140µl diluted urine

 Sample disk: general sample disk, including the inner circle and the outer circle  Sample tube position: 60 positions, including 6 calibrator positions, 3 control

positions, 5 for STAT sample positions; 5 virtual disks for maximum 300 samples

 Sample probe: with a built-in level detector; equipped with auto safeguard;

capable of tracking sample level

 Washing function: automatically washing interior and exterior of sample probe;

carryover no more than 0.1%

 Pre-dilution: 4 ≤ dilution rate ≤ 150, taking reaction cuvettes as the container

 Reagent volume: 30-450ul; Precision: 1ul  Reagent disk: including the inner circle and the outer circle  Reagent position number: 25/50 reagent positions. Each reagent position is

available for containing one Hitachi 7060 bottle, one Hitachi 7170 bottle, one Mindray inner-circle bottle or one Mindray outer-circle bottle.

 Reagent probe: One independent probe which has a built-in level detector; is

equipped with auto safeguard and capable of tracking reagent level

 Washing function: automatically washing interiors and exteriors of reagent probes;

carryover no more than 0.1%

1-1

Specifications

 Mixing bar: for single-reagent tests, it functions after sample dispensing; for

double-reagent tests, it functions after the dispensing of the sample and the second reagent.

1.3 Analysis System Feature

 Lamp house: 50w lamp  Light splitting mode: Splitting by optical fiber, filtering by an interference filter.  Half band-width: 10±2nm  Wavelength: 340, 405, 450, 510, 546, 578, 630, 670, 700nm  Absorbance range: -0.1~5, 10mm optical path conversion  Reaction cuvette: 5 × 6 × 25mm, optical path 5mm. Material: PP, disposable.

Volume: 750uL

 Reaction liquid volume: 180-500µl  Max. reaction time: 20 minutes  Reaction temperature: 37±0.3℃ with fluctuation of ±0.1℃

1.4 Others

 Operating system: Windows 2000 or Windows XP  Display: optional  System interface: RS-232  Printer: optional  Built-in bar code scanner: optional  ISE module: optional

1-2

2 System Installation

NOTE:

The analyzer should be installed or moved to another place by Mindray-authorized personnel only.

2.1 Check before Installation

The user should provide the environment that meets the requirements mentioned in the Operation Manual. Check if the environment meets the requirements before installing the analyzer . Refer to the chapter 2 of the Operation Manual for details.

2.2 Installation Procedure

System Installation

1 Ensure available installation fields and environments in hospitals. 2 Confirm the reagents and calibrators. 3 Go to the installation field, and then check the delivery list for acceptance. 4 Install the four handles on the four angles of the analyzer. Move the analyzer

to the installation field, fix the casters, and then remove the handles. 5 Insta ll the computer, display and printer. 6 Open the front plate, and check whether cable connections are loose. Open

the top plate, check whether the probe assemblies, reagent disk and sample

disk are intact and in good performance. 7 Connect the communication cable, power cable, grounding wire, waste tank

and deionized water tank. Install the used-cuvette bucket, reagent probe,

sample probe and mixing bar. 8 Top up the deionized water tank with deionized water. 9 Put reaction cuvettes in the feeder. Remember to check whether the surfaces

of the cuvettes are smooth. In case of any bump, remove it before loading the

cuvette to the compartment. Do not touch the light transmission part of the

cuvette in which the colorimetric reading is taken. 10 Load acid and alkaline detergents to positions 46 and 47, and distilled water

to positions 49 on the reagent disk. Load distilled water to position 60 on the

sample disk. 11 Switch on the analyzer as follows: POWER → ANALYZING UNIT POWER

→display → computer → printer. 12 After Windows is started, double-click the icon of BS-300 on the desktop to

start the system software. The system program will automatically finish the

self-test, become online and warm up the reaction cuvettes within about 30

minutes. 13 Select the [System/Status] menu, and then observe the system status and

record it in the table below:

2-1

System Installation

Feeder status Unconnected Full Half full Empty Reaction disk

temperature Reagent disk

temperature Ambient temperature Waste tank status Abnormal (full) Normal (not full) Detergent status Abnormal (empty) Normal (available) Printer status No printer Normal Main control unit Unconnected Idle Running Reaction disk unit Unconnected Reagent disk unit Unconnected Sample disk unit Unconnected Loading/unloading unit Unconnected Temperature control

unit Lamp

Unconnected

Network connection Unconnected

Wavelength Dark current Light source base 340 405 450 510 546 578 630 670 700 Reference light system

14 Select the [System/Maintenance] menu. Then select the Motion tab page,

and implement all sub-steps of each unit to see whether they are normal. In

case of any exception, adjust it. 15 Wash the interiors and exteriors of the sample probe, reagent probe and

mixing bar for several times to make the fluid circuit filled. 16 Set parameters for test, reagent and calibration under the Parameters menu.

2-2

System Installation

17 Request for calibration and samples, run and then debug the results. 18 After debugging the results, fill them in the table below:

Test ALT CREA BUN Target value 2sd range Test value 1 Test value 2 Test value 3 Test value 4 Test value 5 Test value 6 Test value 7 Test value 8 Test value 9 Test value 10

19 Training

Can the user complete daily tests? Yes □ No □ Is the user familiar with the analytical methods such as

kinetic, two-point, endpoint? Is the user familiar with the daily, weekly and monthly

maintenance and relevant maintenance methods? Is the user skilled in washing dust screens? Yes □ No □ Is the user skilled in cleaning and replacing the probes

and the mixing bar? Is the user skilled in replacing the plunger assemblies

of syringes? Is the user skilled in replacing the lamp? Yes □ No □ Is the user skilled in maintenance of built-in bar code

scanner? Is the user skilled in maintenance of ISE unit? Yes □ No □ Does the user know the positions, roles and

preparation methods of distilled water and acid and alkaline detergents?

Yes □ No □

2-3

3 System Descriptions

The BS-300 analyzer consists of the analyzing unit, operation unit and output unit. The analyzing unit consists of the dispensing system, feeder, temperature control

system, photometric system and fluid system.

3.1 Dispensing System

The dispensing system consists of the probe assemblies (including the reagent probe assembly, sample probe assembly and mixing bar assembly), reagent disk, sample disk and reaction disk.

3.1.1 Probe assemblies

System Descriptions

Among the probe assemblies, the mixing bar assembly is the same as the reagent probe assembly and the sample probe assembly, except that the knurled axis is 30cm shorter.

Every probe assembly has a horizontal photoelectric switch and a vertical photoelectric switch. These switches are used for defining horizontal and vertical

3-1

System Descriptions

initial positions of probe assemblies. The horizontal and vertical step motors precisely control the horizontal and vertical movements of the probe assemblies, and the synchronizing belts serve as the gearing.

The shaft and the bushing must corporate with each other precisely, so they cannot be used confusedly.

3.1.2 Disk assemblies

The three disk assemblies are different in their coders. The coder corresponds to the position where disks should stop. There is an initial-position mark under every coder. The three coders of the three disks have three coder transducers. Each transducer has two photoelectric switches for inducing the rotation and initial position of the disk.

The step motors control the disk assemblies, and the synchronizing belts serve as the gearing.

3-2

System Descriptions

There is a build-in bar code scanner to the left of the sample disk. The scanner is optional.

3.2 Feeder

The feeder consists of the feeder assemblies and the manipulator. It is designated to send cuvette segments to the reaction disk, take out the used ones and abandon them to the used-cuvette bucket.

3.2.1 Feeder assemblies

The feeder assemblies include the gearing assembly, cuvette compartment assembly, cuvette-pushing assembly and no-cuvette detection assembly (see the following figure).

The supporting plate of the feeder assemblies is a square piece of steel that is connected to the analyzing unit by its four poles, which are secured by four nuts. Unscrewing the nuts, you can disassemble the feeder assemblies from the analyzing unit easily.

Sample probe assemblyBuild-in bar code scanner

3-3

System Descriptions

There are five transducers that are shown in the figure below. The no-cuvette transducer is used to detect whether there is a cuvette segment at

the loading position. The insufficient-cuvette transducer is used for determine whether there are less than 10 reaction cuvettes in the compartment or not. If yes, the analyzer will give a prompt.

Pressure Transducer

No-Cuvette Transducer

3.2.2 Manipulator

Two step motors (horizontal and vertical) supply power for horizontal and vertical movements of the manipulator.

The upper finger and lower finger are same in their structures. They work together to replace used cuvette segments with new ones.

The manipulator runs in a relatively complicated way. There are four transducers on it: vertical transducer, horizontal transducer and two finger transducers.

Cuvette-Pushing Limit Transducer

Insufficient-Cuvette

Transducer

Cuvette-taking limit

transducer

3-4

System Descriptions

3.3 Temperature Control System

3.3.1 Temperature control assembly

The temperature control assembly of the reaction disk consists of the temperature-controlled pot, heat-insulating sheath/plate, top heater, bottom heater, reaction disk/cuvettes, photoelectric seat, temperature transducer, fan and control circuit.

3-5

System Descriptions

1: Temperature transducer and the support 2: Fan 3: photoelectric seat 4: Heat-insulating sheath 5: top heater 6: Cover 7: temperature-controlled pot 8: bottom heater

Upper heater: square in shape, 220/110VAC, 125W Lower heater: ring in shape, 220/110VAC, 350W Total power: 475W. The function of heaters is to compensate the heat for incubating the reagent and for

maintaining the temperature of the temperature-controlled chamber . Fans are used in series in the temperature-controlled chamber. It makes the air

circulating in the chamber, and enhances the convective heat exchange. There are four fans in the chamber. All have the alarm function.

The temperature transducer feeds back the air temperature at the position several millimeters from the bottom of the reaction cuvette.

The overheat protection switch is to switch off the power when the temperature controller does work and the temperature-controlled chamber reaches 55℃, so as to avoid overheat or fire. When the temperature-controlled chamber becomes 35℃, this switch will automatically be reset.

3.3.2 Reagent preheating

The preheating assembly consists of two aluminum plates, a Te flon tube having nine loop sections, heating components, transducer, temperature protection switch, thermal conductive colloid, a section of tube and the reagent probe.

The temperature of the thermal source of the preheater is controlled at 45℃. The initial temperature of the reagent is 4 ~ 10℃ when it is taken out of the refrigeration

3-6

System Descriptions

chamber. When the reagent passes the heater, its temperature increases to 35℃. Then the reagent is added into the reaction cuvette and the preheating process is finished.

Reagent preheating assembly

3.3.3 Reagent refrigeration

The refrigeration module consists of refrigeration cabin, PU heat-insulating sheath, reagent disk, reagent bottle, temperature transducer, refrigeration flakes, heat sinking component, fan and control circuit. The refrigeration module is shown in the following figure.

The refrigeration assembly consists of fan, hot-end radiator, POM connector, cold-end heat-conductive aluminum block, and PELTIER refrigeration flake. Each analyzer has two such refrigeration assemblies, as shown in the figure below. The cold-side of the refrigeration flake clings to the refrigeration compartment, and the hot-side clings to the radiator (The side having letters should cling to the refrigeration aluminum block).

3-7

System Descriptions

Each refrigeration flake corresponds to a heat-sinking block and a cooling fan. It should be installed with the cold side upward.

3.4 Photometric System

The photometric system consists of a measurement photometric system and a reference photometric system. The measurement photometric system provides 9 monochromatic lights to measure the absorbance of the reacting liquid in the rotating reaction cuvettes. The reference photometric system compensates the measurement photometric system to make the measurement more accurate.

Tungsten-halogen

lamp

卤钨灯聚光镜

Biconvex lens

3.5 Fluid System

The fluid system is shown in the following figure.

Main fiber

传光束

Plano

小透镜反应杯滤光片小透镜光电管

convex lens

Fibers

传光束小端

Cuvette Filter

Photodiode

convex lens

共路

光电管

Plano

参考光路

Reference light

Photodiode

测量光路

Measurement

. . .

lights

3-8

Sample syringe

System Descriptions

Reagent syringe

Mixing bar

As shown in the figure above, the fluid system consists of interior washing and exterior washing.

The syringe assembly controls the aspiration volume by controlling the travel of the sample/reagent syringe. It is the core part of the fluid system.

3-9

System Descriptions

3.6 ISE Module (optional)

The ISE module that is used to measure the concentration of K+, Na+, Cl- and Li+ in serum, plasma and urine consists of ion-selective electrodes, peristaltic pumps and calibrants.

ISE

Pump W

Calibrant B

Pump BPump A

Calibrant A

Waste

3-10

System Descriptions

3-11

4 Functions of Boards

The analyzer is integrated with the following boards:

 Main control board  Power drive board  Sample level detection board  Reagent level detection board  A/D conversion board  Ten photoelectric conversion boards (340nm, 405nm, 450nm, 510nm, 546nm,

578nm, 630nm, 670nm, 700nm and reference light)

 Reagent refrigeration board  Power supply assembly  Manipulator connection board  Feeder connection board  Probes connection board

Functions of Boards

Power supply assembly

PFC board

12V&5V board

24V board

ISE power supply board

A/D conversion board

10 photoelectric

conversion boards

Build-in sample bar

code scanner

4.1 Main Control Board

The main control board is the control center of the whole hardware system. It consists of the control circuits of 6 functional units (including main control unit, photoelectric unit, reagent unit, sample unit, loading/mixing unit, temperature control unit). Each functional unit has an MCU. They communicate in the multi-unit mode and thus compose the whole control system.

ISE module

Main control board

Step motors

DC motors

Pumps, valves

Level detection boards

Transducers

Power drive board

Heaters of reaction

disk

Reagent pre-heater

Lamp

Reagent

refrigeration board

Peltiers

transducers

The functions of the main control board are:  communicating with the PC through the RS232, receiving and analyzing

instructions from the PC and sending data to the PC.

 controlling photoelectric conversion through the interface with the A/D conversion

board, reading and saving data from the A/D conversion board.

 outputting control signals of each unit through the interface with the power drive

board.

4-1

Functions of Boards

 receiving signals of fluid level detection and bump collision through the interface

with the level detection boards.

 detecting signals from temperature transducers and controlling temperature of the

reaction disk and reagent preheating.

 receiving signals from position transducers, deionized water transducer and waste

transducer and controlling the transducers.

 controlling the built-in sample bar code scanner, reading the data and sending it to

the PC.

 controlling the ISE module, reading the results and sending them to the PC.

4.2 Power Drive Board

The main functions of the power drive board are to receive the control signals from the main control board and control drive components. The block diagram of the power drive board is shown in the figure below.

Control signals from Main Control Board

to 13 step motors to 2 DC motors

to 2 solenoid valves to 3 pumps

to 2 heaters of

reaction disk

4.3 A/D Conversion Board

The 10 photoelectric conversion circuits convert the intensity signals of the lights transmitting through the reaction cuvettes to electric signals, and then transmit them to the A/D conversion board through a 5-core shielded cable. Photoelectric conversion boards for different wavelengths have different gains and cannot be replaced by each other.

The A/D conversion board filters and amplifies the 10 channels of electric signals output from the photoelectric conversion boards, transmits them through the multi-way gating switch to the A/D converter and then sends them to the main control board for further processing.

to lamp power

to 2 magnets

to reagent preheating

4.4 Reagent Refrigeration Board

The circuits of the reagent refrigeration board include the refrigeration circuit and the fan circuit.

The refrigeration circuit is needed to work continuously, so it is powered separately. The control objects of the reagent refrigeration board include: Reagent refrigeration: 2 PELTIER components, 4 fans.

4-2

Heat sink system for the whole device: 3 lamp-cooling fans, 4 temperature control fans of the reaction disk.

4.5 Level Detection Boards

The level detection boards that include sample level detection board and reagent level detection board are used to detect the fluid level of sample and reagent separately. When the analyzer aspirates reagents/samples, the probes dip into the liquid to a specific depth, so as to avoid carryovers that have impacts on test results, and to avoid air aspiration when the reagent/sample is insufficient.

4.6 Feeder Connection Board

The feeder connection board transfers the signals between the feeder transducer and the main control board, and connects the power drive board and the loading motor (DC).

Functions of Boards

Connections:

Connector Connected with

J91 Front transducer J92 Back transducer J93 Intermediate transducer J94 No-cuvette transducer J95 Pressure transducer J96 Motor control wire (connected with the power drive board) J97 Motor control wire (connected the motors) J98 Cuvette-loading button J99 Connection wire of the main control board

4.7 Manipulator Connection Board

The manipulator connection board transfers the signals between the manipulator transducer and the main control board, and connects the power drive board and the electromagnet.

Connections:

Connector Connected with

J101 Horizontal loading position transducer J102 Vertical loading position transducer J103 Electromagnet-closing transducer of the lower hand

4-3

Functions of Boards

Connector Connected with

J108 Electromagnet-closing transducer of the upper hand J104 Drive wire of the electromagnet of the upper hand J105 Drive wire of the electromagnet of the lower hand J106 Drive wire of the electromagnet (connected with the power drive

board) J107 Connection wire of the main control board J109 Safeguard transducer (reserved) J110 Safeguard transducer (reserved)

4.8 Probes Connection Board

The probes connection board transfers the signals between the sample/reagent level detection board and the main control board, inputs the temperature signals, outputs the reagent preheating signals, and transfers the signals between the power drive board and the mixing motor (DC).

Connector Connected with

J200 Interface of the sample level detection board J201 Interface of the reagent level detection board J202 Interface of the mixing motor (DC) J203 Sample detection signal interface of the main control board J204 Reagent detection signal interface of the main control board J205 Temperature control signal interface of the reaction disk J206 Reagent preheating signal interface J207 Interface of the power drive board

4.9 Power Supply Assembly

The power supply assembly consists of three boards: PFC board, 24V board, 12V&5V board and ISE (optional) power supply board.

The functions of the PFC board include:

 AC/DC conversion;  Supplying the +390V and VDD voltage to the 24V board and the 12V&5V board;  Supplying stable 12V voltage for the lamp;  Supplying control signals of the analyzing unit switch to control the C12V, 5V and

24V outputs.

The 24V board converts the 390VDC current transmitted from the PFC board to the separated 24VDC outputs through the forward converter.

4-4

Functions of Boards

The 12V&5V board converts the 390VDC voltage from the PFC board to B12V, C12V and 5V voltages through the forward converter .

The ISE power supply board converts the 12V of the reagent refrigeration board to 24V that provides power supply for the ISE unit (optional).

4-5

5 Maintenance and Service

WARNING:

Before disassembling or assembling the analyzing unit, ensure the POWER is placed to OFF.

The probe tip is sharp and can cause puncture wounds. To prevent injury, exercise caution when working around the probe.

BIOHAZARD:

Wear gloves and lab coat and, if necessary, goggles. Dispose of the waste in accordance with your local or national

guidelines for biohazard waste disposal.

CAUTION:

Please use Mindray-recommended consumables. Other consumables may decrease the system performance.

Maintenance and Service

Refer to the BS-300 Chemistry Analyzer Operation Manual for details about

 unclogging the sample probe  unclogging the reagent probe  replacing the sample probe  replacing the reagent probe  replacing the mixing bar  replacing the plunger assembly of syringe  replacing the lamp

5.1 Replacing Light Filter Assembly

The light filter and optical assembly are fixed in the supporting sleeve. The back end is compacted and enclosed with the photoelectric amplification board and the screen gland. Generally, the supporting sleeve is replaced together with the filter and optical assembly.

5-1

Maintenance and Service

Figure 5-1 Light filter assembly

Gasket

Supporting Sleeve

Filter

Flat Spring

Lens

Lens Seat

Gasket

Screw

Photoelectric

Conversion Board

Shield Box

WARNING:

Before operating, ensure to place the POWER (main switch) to OFF.

1 Unscrew (counter clockwise) the two cap screws on the screen gland

whose wavelength is to be replaced.

2 Open the cover of the A/D conversion board, and unplug the plug

corresponding to certain wavelength.

5-2

Maintenance and Service

3 Take out the photoelectric conversion board and the supporting sleeve.

4 Keep the photoelectric conversion board upward, and loosen the two

retaining screws on it.

5 Keep the photoelectric conversion board upward, and pull the photoelectric

amplification board out of the supporting sleeve.

6 Unpack the new supporting sleeve containing the optical assembly. Be sure

to keep the top side (where to assemble the photoelectric amplification board) of the supporting sleeve upward.

7 Install the original photoelectric conversion board onto the new supporting

sleeve, and then fasten the two retaining screws.

8 Install the screen gland, and fasten the retaining screws.

5-3

Maintenance and Service

9 Connect the photoelectric conversion board to the A/D conversion board,

and assemble the cover.

WARNING:

When replacing the light filter assembly, do not touch the optical assembly in the supporting sleeve and the photoelectric receiving tube of the photoelectric conversion board by hand.

The light filters and the photoelectric conversion boards are in one-to-one relationship. Do not disarrange them.

5.2 Replacing Optical Fiber

WARNING:

Before operating, ensure to place the POWER (main switch) to OFF.

1 Unscrew the four screws on the supporting pillars of the cuvette feeder, and

remove the cuvette feeder.

5-4

Maintenance and Service

2 Unscrew the four screws on the reaction disk cover, and open the reaction

disk cover. Attention should be paid to the power cable of the upper heater when the

reaction disk cover is being opened.

Power cable of

upper heater

3 Take out two cuvette segments in a diagonal with the needle-nose pliers to

make two spaces for disassemble the colorimetric disk.

4 Unscrew three M3 cap screws, and then disassemble the colorimetric disk.

5-5

Maintenance and Service

5 Use an M3 cap screwdriver to loosen the retaining screws of the optical

fibers on the colorimetric clamp and the reference light support.

6 T ake out the optical fibers one by one, and fix the optical component s in the

colorimetric clamp by fastening the screws slightly.

Screw of the reference light

7 Draw out all the nine optical fibers from the reaction compartment. 8 Loosen the M3 cap screw (used for retaining optical fibers) on the lamp

housing, and then draw out the optical fibers.

9 Put nine of the ten branches of the new optical fiber into the reaction disk

from its bottom one by one, loosen the retaining screw, insert the optical fiber to the end, and then fasten the retaining screw.

10 Fix the reference light optical fiber.

5-6

Maintenance and Service

11 Fix the optical fiber of the lamp housing. 12 Put the colorimetric disk back and fix it. 13 Put the reaction disk cover back and fix it. 14 Install the cuvette feeder and fix it.

CAUTION:

When replacing the optical fiber, ensure that its bending radius is no less than 20cm. Otherwise, the optical fiber will be damaged.

5.3 Adjusting Reaction Disk, Manipulator and Feeder

NOTE:

Debug the lower arm first (The relation between the lower arm position and the reaction cuvette position is very important.), and then the upper arm. When debugging the lower arm, move the cuvette compartment aside.

1 Disassemble the cuvette feeder, and adjust the circular position of the

reaction disk (through the initial position transducer of the reaction disk) to the standard position (The finger of the lower arm point s to the cen ter of the slot between reaction cuvette segments).

2 Horizontally adjust the manipulator to the standard position (The finger of

the lower arm can work on reaction cuvettes well, and it should be 0.2mm away from the nearest point of the reaction cuvette).

5-7

Maintenance and Service

3 Vertically adjust the manipulator the standard position (The finger of the

lower arm can work on reaction cuvette well, and the finger support of the lower arm should be 0.15mm above the reaction cuvette.).

4 Run the manipulator to the position for taking new cuvettes, and

horizontally adjust the reaction cuvettes in the feeder. When catching a cuvette, ensure a clearance of 0.4mm ~ 0.6mm between the finger of the upper arm and the cuvette, and center them.

5.4 Adjusting Probes and Disks

NOTE:

Adjust the positions of the three probes and reaction cuvettes, and then others.

Adjust the working position of the reagent probe (To minimize the

cumulative error, ensure that the reagent probe return to the initial position before each adjustment.) as follows:

A For the reagent discharging position, ensure the reagent probe is in

the center of the reaction cuvette and the probe tin is 2 ~ 3mm away from the bottom of the reaction cuvette.

B Adjust the position of the initial-position transducer of the reagent

disk. Ensure the mouths of reagent cuvettes in the inner and outer circles fit the reagent disk cover well.

C Adjust the washing position of the reagent probe. Ensure the reagent

probe is in the center of the wash well and the probe pin is 5mm away from the bottom of the wash well. If necessary, adjust the position of the wash well.

D Adjust the reagent probe’s position on the outer circle of the reagent

disk. Ensure the reagent probe is in the center of the hole of the outer circle.

5-8

Maintenance and Service

E Adjust the reagent probe’s position on the inner circle of the reagent

disk. Ensure the reagent probe is in the center of the hole of the inner circle.

Adjust the working position of the sample probe (To minimize the

cumulative error, ensure that the sample probe return to the initial position before each adjustment.) as follows:

A For the sample discharging position, ensure the sample probe is in

the center of the reaction cuvette and the probe tin is 2 ~ 3mm away from the bottom of the reaction cuvette.

B Adjust the position of the initial-position transducer of the sample

disk. Ensure the mouths of sample cuvettes in the inner and outer circles fit the reagent disk cover well.

C Adjust the washing position of the sample probe. Ensure the sample

probe is in the center of the wash well and the probe pin is 5mm away from the bottom of the wash well. If necessary, adjust the position of the wash well.

D Adjust the sample probe’s position on the outer circle of the sample

disk. Ensure the sample probe is in the center of the hole of the outer circle.

E Adjust the sample probe’s position on the inner circle of the sample

disk. Ensure the sample probe is in the center of the hole of the inner circle.

Adjust the working position of the mixing bar.

A Switch off the analyzing unit first, and then rotate the mixing arm to

see if its rotation radius is proper. If the mixing bar cannot reach the center of the reaction cuvette, adjust the position of the mixing bar on the mixing arm properly.

B Disassemble the mixing arm, and then switch on the analyzing unit to

run the reaction disk and stop it at any cuvette. Hold the mixing arm by hand, and fix it at the center of the reaction cuvette.

C Vertically adjust the mixing bar’s position in the reaction cuvette.

Ensure the mixing bar tip is 1 ~ 2mm away from the bottom of the reaction cuvette.

D Adjust the washing position of the mixing bar. Ensure the mixing bar

is in the center of the wash well and about 5mm away from the bottom of the wash well. If necessary, adjust the position of the wash well.

4 In the engineering adjustment software, select the Debug instruction

menu, and rotate the reaction disk for one lap. Dive probes and mix the reactant at every position or every several positions to see if the three probes interfere with any reaction cuvette (Command 61). If the mixing bar knocks the side or the bottom of any cuvette, repeat Step 3.

5-9

Maintenance and Service

5.5 Replacing Components of ISE Unit (optional)

5.5.1 Replacing Tubing

NOTE:

(1) Fluidic tubing can be divided into the following six types. W1 with two adapters connects the ISE module and the pump W.

Pump module

ISE module

Reagent module to be

placed here

Pump B Pump A

Pump tubing adapter

Pump tubing

Pump head

Pump W

Fluidic tubing adapter

W2 connects the reagent module and the pump W. A1 (B1) with one adapter connects the sample entry port and the pump

A (pump B). A2 (B2) with two adapters connects reagent module and the pump A

(pump B). They are different in length and W1, A2 and B2 are not directional

when they are installed. Usually the adapter has not been mounted to the fluidic tubing, so you

have to do it by hand. The tubing should be mounted to a short metallic tube on the adapter. For convenience, the connectin g end of the tubing can be dipped into hot water for several seconds.

(2) Pump tubing is used around a pump head. It has one adapter on each end that makes connection with the fluidic tubing easy.

5-10

5.5.1.1 Replacing Fluidic Tubing W1 and W2

1 Place the POWER to OFF. 2 Open the ISE unit door. 3 If you want to replace the W1, unscrew the screw of the ISE module and

take off the cover.

4 Put out the fluidic tubing W2 and insert it into a container such as a cup that

is used to contain the waste solution flowing from the W2. 5 Start the analyzing unit and the system software. 6 Enter the ISE Maintenance screen of the system software. 7 Click the Maintenance button several times until there is no solution

flowing out from the W2. 8 Place the POWER to OFF. 9 If you want to replace W1, pull out its two adapters directly from the waste

pump tubing adapter and the right angle adapter that is fixed to the

compression plate.

Maintenance and Service

Right angle adapter

The side matches the adapter of fluid tubing W1

The side with a recess matches the compressio n plate of the ISE module.

Note that when pulling out the fluidic tubing adapter, in order not to release

the right angle adapter, you can hold the right angle adapter with a finger.

After that, install a new W1. For W2 exchange, it just needs to replace the

W2 with a new one. 10 If you want to replace the W2, replace it with a new one. Otherwise, insert

the W2 back to the reagent module. 11 Place the POWER to ON. 12 Enter the System Maintenance screen of the system software. 13 Select the Others tab and click the Download Settings button. 14 Enter the ISE Maintenance screen. 15 Click the A purge button to observe if there is solution leaking out. If there

is solution leaking out, repeat from the step 4 to install the tubing again. 16 Install the cover of the ISE module if it has been taken off. 17 Close the ISE unit door.

5-11

Maintenance and Service

5.5.1.2 Replacing Fluidic Tubing A1, A2, B1 and B2

1 Place the POWER to OFF. 2 T ake off the panel under the sample disk and you can see the shiel ding box

and the peristaltic pumps. 3 Open the ISE unit door. 4 Take out the reagent module. 5 Put the fluidic tubing W2 in a container such as a cup that is used to contain

the fluid flowing out from the W2. 6 Start the analyzing unit and the system software. 7 Enter the ISE Maintenance screen of the system software. 8 If you want to replace A1 or A2, click the A purge button. If you want to

replace B1 or B2, click the B purge button.

Repeat this step for several times until the received data indicates that the

Calibrant A or Calibrant B has air bubble in it. 9 Place the POWER to OFF. 10 Replace the tubing with a new one.

Note that before installing the A1 or B1 to the sample entry port, you can

dip the connecting end of the A1 or B1 into hot water for several minutes to

make the following procedures easily performed. 11 Start the analyzing unit. 12 If the system software is not running, start it. Otherwise, enter the System

Maintenance screen of the system software, select the Others tab and

click the Download Settings button. 13 Enter the ISE Maintenance screen of the system software. 14 If you have replaced A1 or A2, click the A purge button. If you have

replaced B1 or B2, click the B purge button.

Repeat this step for several times until the received data indicates that the

Calibrant A or Calibrant B has no air bubble in it.

5.5.1.3 Replacing Pump Tubing

1 Place the POWER to OFF. 2 Open the ISE unit door. 3 Pinch one adapter of the pump tubing and take it out from the tubing shelf.

Then take off the whole tubing.

Tubing shelf

5-12

4 Put one adapter of the new pump tubing onto the tubing shelf and make the

tubing around the pump ahead, then put the other adapter onto the shelf

with a little strength. 5 Start the analyzing unit and the system software. 6 Enter the ISE Maintenance screen. 7 Click the Pumps button to see if the calibration of pump is correct. If not,

repeat the upper steps.

5.5.2 Replacing Pumps

1 Place the POWER to OFF. 2 Take off the pump tubing around the pump head. 3 Disconnect the cable and the pump motor.

Maintenance and Service

4 Unscrew the four screws around the pump head. 5 Pull out the pump directly. 6 Put a new pump on the pump shelf, tighten the screws, connect the calbe

and pump motor, and then put the pump tubing around the pump head. 7 Start the analyzing unit and the system software. 8 Enter the ISE Maintenance screen. 9 Click the Pumps button to see if the calibration of pump is correct. If not,

repeat the upper steps.

5.5.3 Replacing ISE Module

Some times there is something wrong with the components in the ISE module such as sample entry port, bubble detector, PCB and so on. In these cases, the ISE module should be replaced according to the following procedure.

Cable

Pump motor

1 Place the POWER to OFF. 2 T ake off the panel under the sample disk and you can see the shiel ding box

and the pumps easily. 3 Open the ISE unit door. 4 Start the analyzing unit and the system software. 5 Enter the ISE Maintenance screen.

5-13

Maintenance and Service

6 Click the Maintenance button. 7 Place the POWER to OFF. 8 Unscrew the screw of the ISE module and take off the cover. 9 Take off all electrodes from above to below. 10 Disconnect the right angle adapter and the compression plate. 11 Disconnect the cable. 12 Unscrew the four screws that fix the ISE module to the shielding box. Then

take out the module from the shielding box. 13 Put a new ISE module to the shielding box. Then connect the cable and

install the electrodes sequentially. At last mount the right angle adapter to

the compression plate. 14 Install the electrodes sequentially. 15 Enter the System Maintenance screen of the system software. 16 Select the Others tab and click the Download Settings button. 17 Enter the ISE Maintenance screen. 18 Click the A pur ge button to see if there is solution leaking out. If there is,

take off the electrodes and install them again. 19 Check if the new ISE module can work normally.

5-14

6 Software Introduction

The software of BS-300 analyzer is composed of the system sof tware an d the control software.

6.1 System Software

The system software can, according to the requirements and inputs of users, generate a work schedule (instruction sequence), control the units of analyzing unit in the sequence of instructions in the work schedule, receive photoelectric data, response messages or execution results from the analyzing unit, output them to the PC screen or the printer. With these outputs, users can obtain correct test results.

According to different functions, the entire PC softwa re system can be divided into the following parts:

 System Initialization This part includes the initialization of the PC operating system, the initialization of the

communication between the PC and analyzing unit, and the controls of analyzing unit reset.

Software Introduction

 Control system This part includes the formation of the work schedule, instruction data sending and

receiving.  GUI

This part includes the requests for tests (routine tests, emergency tests, calibration tests and QC tests), the observation of test statu s (status of the reaction disk, sample disk and reagent disk), test management, calibration management, QC manage ment, result query, alarm management and the help system.

 Shutdown Processing This part includes the resets of sub-units.

6.1.1 System initialization

To initialize the PC operating system,  Check the PC operating system. The system software must run under Windows

2000 or Windows XP. Otherwise, the system will prompt that the system software cannot run under other operating system, and then the system software system exits automatically.

 Check the current screen resolution for the operating system. The system software

must run under the resolution of 1024 × 768. Otherwise, the system prompts to reset the resolution before restarting the system software and exit the system software.

 Disable the screen protection program. The system software must keep displayed

while running. To prevent the screen protection program from disturbing users in the operating and observing processes, disable it.

 Lock the keyboard. When running, the system software will lock some key

combinations to prevent users from starting any other program and condu cting any

6-1

Software Introduction

other operation. In this case, users cannot switch over to any other program or print the current screen.

 Check whether there is any username and password of the

maintenance/debugging personnel in the registry. The system software has the debugging function. Only the authorized maintenance/debugging personnel can enter the debugging window and maintain or debug the system and the host. For the confidentiality, the username and password are saved in the registry. If they are unavailable in the registry, the system will re-write the default username and password into the registry.

To initialize the communication and the units auto-check,  Set serial ports and initialize them, including such parameters as the baud rate,

data bit, start bit, stop bit, parity bit, transmitting/receiving buffer, control protocol and so on. In addition, start the serial port receiving thread.

 Handshake for communication. Send a handshake instruction to the analyzing unit.

If the analyzing unit responds to this instruction (namely, send back a handshake instruction to the PC), it indicates the PC handshakes with the host successfully. If the host fails to respond to handshake instruction, it will re-send the handshake instruction back in a specific period. If it fails for continuously three times, the system will prompt to exit the system software. If you ignore that and continue to enter the system software, all tests cannot be conducted under the system.

 Check whether the printer is connected. If not, the system will prompt to connect it.  Send an instruction for querying the auto-check results of the units, check the

auto-check result of each unit. (The units are auto-checked when the analyzing unit is started, and the auto-check results are stored in the main unit.) In case of any fault data in the auto-check result of any unit, the system will prompt to switch off the analyzing unit and check the faulty unit.

6.1.2 Shutdown processing

In the BS-300 Chemistry Analyzer Control System window, click the Exit button. The Confirm dialog box appears. If you click OK, the system will

 Switch off the lamp;  Unload all reaction cuvettes;  Wash the fluid tubing;  Reset all units;  Unlock the keyboard;  Prompt to exit the operating system and shut down the PC.

6.2 Control Software

The analyzing unit can be functionally divided into the following units: photoelectric unit, reaction disk unit, reagent disk unit, sample disk unit, reagent probe syringe unit, sample probe syringe unit, mixing bar unit, loading and manipulator unit, temperature control unit, fluid tubing unit and reagent refrigeration unit. The functions of those units are listed in the following table.

6-2

Software Introduction

Unit Function

Main unit Receives macroinstructions from the PC, decomposes them

into a series of action instructions, and then delivers the action instructions to destination sub-units (in specific order) at a certain interval.

Monitors the status of other units, and transmits data collected by the photoelectric unit to the PC.

Photoelectric unit

Reaction disk unit

Reagent disk unit

Sample disk unit

Reagent probe syringe unit

Photoelectrically detects, amplifies and converts the solution in reaction cuvettes, and stores A/D converted data at the twin port FIFO for the main unit to read and transmit them to the PC.

Contains 80 cuvette No. Runs the reaction cuvette with the specified No., following

the instruction of the main unit, to the reagent dispensing position, sample dispensing position, mixing position, and photoelectric detection position at all wavelengths.

Contains 50 bottle positions. Carries reagents, and runs the reagent bottles with specified

No., following the instruction of the main unit, to the reagent aspirating position.

Contains 60 tube positions in the inner and outer circles. Carries samples, and runs the sample tubes with specified

No., following the instruction of the main unit, to the sample aspirating position.

Receives instructions from the PC, and controls the reagent probe in aspirating a specific volume of reagent from the reagent bottle and dispensing it to the specified reaction cuvette.

Sample probe syringe unit

Mixing bar unit Receives instructions from the PC, and controls the mixing

Loading and manipulator unit

Receives instructions from the PC, and controls the sample probe in aspirating a specific volume of sample from the sample tube and dispensing it to the specified cuvette.

bar in mixing the solution in the cuvette that has been run to the mixing position.

Runs the mixing bar to the wash well, and wash it after each mixing process to avoid carryover.

Controls the cuvette feeder and manipulator. The feeder assembly is responsible for detecting whether

there are enough reaction cuvettes in the cuvettes compartment and pushing reaction cuvettes to the position for the manipulator to take cuvettes.

The manipulator is responsible for taking reaction cuvettes from the reaction disk, placing them into the used cuvette bucket, taking new reaction cuvettes from the cuvette compartment, and putting them on the reaction disk.

6-3

Software Introduction

Unit Function

Temperature control unit

Fluid tubing unit Controls the fluid tubing in washing the reagent probe,

Controls the reaction disk temperature, reagent probe preheating temperature and fluid tubing.

Note: The reaction disk temperature should be kept at 37 , ℃ the heating cavity of the reagent probe should be preheated to 45 ℃.

sample probe and mixing bar.

Reagent refrigeration unit

Refrigerates the reagent chamber and controls its temperature between 4 ~ 10 .℃

6-4

Service Flow

7 Service Flow

WARNING:

Before disassembling or assembling the analyzing unit, ensure the POWER is placed to OFF.

The probe tip is sharp and can cause puncture wounds. To prevent injury, exercise caution when working around the probe.

When you disassemble or replace any board, ensure to wear antistatic gloves.

BIOHAZARD:

Wear gloves and lab coat and, if necessary, goggles.

7.1 Fluid Level Detection Failure of Reagent Probe

Surface detection failure of reagent probe(Th e reagent probe does not detect the surface on the reaction disk.)

The

reagent

probe

cannot

detect

the

surface

on the

reagent

disk

Surface detection signal transmission error: The surface detection board does not have the working voltage, or when the probe touches the surface, the indicator of the surface detection board is normal, but there is always a host alarm indicating surface detection failure.

Possible cause: The patch cord for the reagent surface detection is

disconnected, or the connector is not well connected.

Surface detection signal processing error: When the probe touches the surface, the indicator of the surface detection board is normal, the connection between the main control board and the surface detection board is normal, and no surface detection signal reaches the main control board, but there is always a host alarm indicating surface detection failure.

The surface

detection

signal fails

to be

generated

capacitance

change.

Possible cause: Main control board.

Power failure: The working voltage of the surface detection board is 12V. In case of no power supply, the surface detection signal cannot be generated. Possible cause: Disconnection; the connector is not well connected; there is no 12V out put from t he main cont rol board.

Probe failure: The detection terminal has a changeable capacitance. Loose exterior or interior of the probe, the sealing-off of the probe connecting wire and the probe breakage will result in unsteady voltage or obvious voltage changes. In this case, the capacitance signal will be unavailable or exceed the range of the surface detection board.

Possible cause: Reagent probe assembly, connector.

Surface detection board failure: When there is no probe failure, but the indicator is always on, or the indicator is not on when the probe touches the surface, there must be a surface detection board failure.

Troubleshooting: Replace the surface detection board.

The

reagent

probe mis-

detected

the surface

When this failure occurs, the sample probe cannot detect

the surface at the reaction disk, but there is no alarm at

the reagent unit. For details, see Surface Detection

Failure: Sample Probe.

7-1

Service Flow

7.2 Fluid Level Detection Failure of Sample Probe

No reagent in the reaction disk: The reagent probe misdetects the surface, aspirates air and dispenses into the reaction cuvette. Therefore, the reagent unit CPU fails to make any judgment. In this case, the sample probe cannot detect the surface when dispensing the sample into this

The sample

probe cannot

detect the surface at the reaction disk.

reaction cuvette. Possible cause: Surface detection failure of the reagent probe

insufficient reagent: The reagent probe aspirates less reagent than the set volume. As a result, the sample probe cannot detect the surface at the preset height.

Possible cause: The reagent is prepared in the bottle, the

reagent syringe is not fixed, leakage occurs in the tubing of

the reagent probe, or there are bubbles in the reagent.

Position correction parameter error of the sample probe: In case of such an error, the sample probe cannot reach the surface in the steps. Troubleshooting: Re-correct the sample probe position.

Surface

detection

failure of

the

sample

probe

The sample

probe cannot

detect the surface at the reaction disk.

The sample probe misdetects the surface (In this case, there will be no alarm, but test results will become abnormal. On the reaction curve, you can see that no sample is added.)

Surface detection signal transmission failure: When the probe touches the surface and stops, the indicator of the surface detection board is on for about 2 seconds. The output signal of the surface detection board switche s normally, but there is always a host alarm indicating that no surface is dete cted. Possible cause: The patch cord for detecting the sample surface is disconnected, or the connector is not well connected.

Signal processing failure of the main control board: When the probe touches the surface, the indicator works normally. But there is always a host alarm indicating that no surface is detected. Ensure that the sample surface detection signal is transmitted to the relevant connector of the main control board.

Possible cause: Main control board failure

Surface detection signal failure: The indicator of the surface

detection board is not on or always on when the sample

probe touches the surface.

Surface mis-detection at the sample d isk: In this case, there will be no alarm, but the sample probe fails to aspirate the sample, and the test result and reaction curve become abnormal.

Possible cause: Sample probe, surface detection board,

surface detection patch cord.

Surface mis-detection at the reaction disk: In this case, there will be no alarm, but there is residual sample on the sample probe tip, and drops on the table when the probe leaves the reaction disk.

Possible cause: The sub-unit software is later than V1.7, or

the sample probe is not in the center of the reaction cuvette.

7-2

7.3 Liquid Dropping From Probes

Drips drop from the sample probe due to fluid tubing leakage. In this case, there will be liquid dropping

onto the table widely, and there may

be liquid dropping even when the

sample probe is static.

Troubleshootin

g for the liquid dropping from

the reagent

probe and

sample probe.

Drips drop from the sample probe

due to surface detection failures. In

this case, most liquid drop on the

area between the reaction disk and

the wash well.

Service Flow

Tubing leakage due to the abraded syringe piston

Troubleshooting: Replace the syringe or the

syringe piston

The reagent probe takes liquid from the reaction disk. The reagent probe did not detect the surface at the reaction disk, and dispenses the reagent at the corresponding height. If the reagent probe cannot touch the surface at the position for dispensing reagent, the last reagent drop will be taken out by the reagent probe. Possible cause: The probe arm is installed at a too high position; the position of the sample probe has not been corrected; the syringe is loose; there are bubbles in the reagent bottle.

The sample probe takes liquid from the reaction disk. The sample probe detects the surface and stops immediately. Then it dispenses the sample at 1mm under the surface. If the reagent probe mis-detects the surface, the dispensed sample will fail to be added into the reagent, but taken at the probe tip and drops when the probe is moving. As a result, some test results become abnormal.

Possible cause: There are bubbles in the

reaction cuvette; the sample probe is not in the

center of the reaction cuvette, and its position

has not been corrected.

Other failures

Drips taken from the reagent disk or sample disk and dropping from probes

Such failures are usually followed by alarms

indicating that no surface is detected at the

reagent/sample disk. The reagent/sample

probe does not aspirate reagent/sample, but

the reagent/sample probe will stretch out to the

bottom of the reagent bottle/sample tube due to

surface detection failures. As a result, reagent/

sample liquid will be taken on the exterior of

the probe and drop while the probe is moving.

Probe being bent

Troubleshooting: Replace the probe.

Smudges on the sample probe absorb some liquid and drop it while the probe is moving.

Troubleshooting: Cleaning the sample probe.

Probe driving assemblies are not assembled well, resulting in probe jittering and liquid dropping in the vertical movements.

Troubleshooting: Adjust or replace the probe

driving assemblies.

7-3

Service Flow

7.4 Failing to Detect Level of Water for Washing Exteriors

Surface detection signal failure: See relevant resolutions for the

surface detection failure.

No water in the wash water tank: Users

can see this failure in the alarm

information detergen t em pty. In case of

no alarm information, check whether

Failing to Detect the Surface of the Water

for Washing Exteriors

there is any problem in the detergent tank

Pump damaged: In this case, there will be no water in the three wash wells.

Troubleshooting: Replace the pump.

No water in the

wash well

Tubing blocked: In this case, there will be insufficient water for washing exteriors, the three water flows are no t the same, or there will be no water in any of the three wash wells.

Possible cause: The unidirectional valve

is blocked, or the detergent entrance is

cover assembly.

blocked.

Reagent or sample probe. Solution: Replace a probe

The tube is disconnected. Possible cause: The tube is degraded, or other causes.

Troubleshooting: Connect the tubes

again.

7-4

7.5 Abnormal Results

7.5.1 All Results Being Abnormal

All results are

lower than

normal

results.

All test

results are

abnormal

Some results

are higher,

and some are

lower, with

bad

repeatability.

Service Flow

No sample or insufficient sample is added. In this case, it can be seen on the reaction curve that the absorbance has not increased in the period for adding the sample. The reaction curve is even, and many results are 0.

Possible cause: Sample probe blocked, tubing

leakage, syringe not fixed, valve not shut tightly.

The reaction is not thorough. If the sample is not mixed uniformly with the reagent, the reaction will not be thorough, and the light cannot detect the changes of the absorbance.

Possible cause: The mixing bar did not mix the

reacting liquid.

The volumes of dispensed sample are not the same. In this case, it can be seen from the reaction curve that the response is proportional to the volume of the sample. Possible cause: Tubing leakage, valve not shut tightly, or cuvette segments not cleaned well.

7.5.2 Some Results Being Abnormal

Good repeatability

Bad repeatability

Observe the reaction curve, and find the possible

Some test results are

abnormal.

All test results are approaching to 0. Observe the reaction curve first. Possible cause: The lamp base of corresponding wavelength exceeds 65535; the photoelectric detection unit fails to detect the change of absorbance, reagent failure and optical fiber disconnection.

Troubleshooting: Re-calibrate it.

causes.

7-5

Service Flow

7.5.3 Several Results Being Abnormal

Several test results are too low. In this case, observe the reaction curve first.

Possible cause: Drips dropping from the sample

Several test results are

abnormal

Several test results suddenly become too high. In this case, observe the reaction curve first.

Possible cause: There are bubbles in the current

cuvette; the mixing bar knocks the cuvettes.

probe

7-6

7.6 Insufficient Light Intensity of Lamp

Insufficient Light

Intensity of the Lamp

Record the lamp background value and gain

Measure and record the lamp background value and gain

Service Flow

Lamp background values of all

channels decreases.

Estimate whether the

lamp has worked for

2000h (lifetime),

replace Lamb

S E Y

Adjust the gain parameter to make the

lamp base AD values of all channel

lamps increase to about 62000.

Remove the fault alarm

YES

Lamp base values of several

channels decreases

Replace lamb

Replace the lamp.

Check whether the AD value of the

channel whose lamp vase value is

smaller increases obviously.

Replace the lamp with

the original lamp

Replace the photoelectric transducer

assembly, and then check whether the

lamp base value increases obviously.

YES

Replace the

photoelectric

transducer assembly.

Replace the optical

fiber

YES

Change the positions with the

smaller fiber end, and check

whether the lamp base value

increases obviously.

O N

Check whether the photometric

system (such as the lens)

Clean the

photometric system

(such as the lens)

corresponding to the fiber channel

YES

is covered with dirt or the like. (If

yes, clean it.) Then check whether

the lamp base value increases

obviously

Note: Do not adjust the photoelectric gain parameter in case you have no idea about the

cause for the alarm indicating insufficient light intensity of the lamp.

7-7

Service Flow

7.7 Temperature Control Failure

Temperature control failure

Query and record the

fault log codes and

descriptions.

Monitor the temperature

curve.

Obtain the current

temperature control

parameter, and check

whether it is the same as the

factory parameter.

Replace the

temperature

transducer.

Replace the heating

assembly.

Enable and disable the

temperature control function

repeatedly for 2 ~ 3 times

Check whether the temperature

transducer is normal.

yes

Check whether the heating

resistance is normal.

S E Y

Restart the analyzer and then

check whether it is normal.

To monitor the temperature curve

A In the BS-300 Chemistry Analyzer Control System window, select

the [System/Temperature] menu. A dialog box appears. Enter

BS300DEBUG and MINDRAY respectively in the User Name and Password text boxes. Then click OK to enter the Temperature Control Curve window.

B Set a proper temperature range for observing the change of the

temperature curve, and then click the Start button.

7-8

C Minimize the Temperature Control Curve window for future

observation at any time.

D After that, print or snap the temperature curve and then return it to

the headquarters together with the service work report.

To measure the impedance of the temperature transducer

A Switch off the BS-300 analyzer. B Open the left side plate of the BS-300 analyzing unit to expose the

main control board.

C Unplug J45 (reagent preheating temperature transducer), and

measure the resistance between PIN1 and PIN3 with a multimeter. The relation between the resistance and the temperature is: 25℃ /1100Ω, 38.5℃/1145Ω, 45℃/1170Ω, 50℃/1170Ω.

D Unplug J44 (reaction disk temperature transducer), and measure the

resistance between PIN1 and PIN3 with a multimeter. The relation between the resistance and the temperature is: 25℃/1100Ω, 38.5℃ /1145Ω, 45℃/1170Ω, 50℃/1170Ω.

To measure the resistance of the heater

Service Flow

A Measure the impedance of the reagent preheater in the following

procedures: Unplug J24 (power driving board) Measure the impedance between PIN1 and PIN2. Reagent preheater

(BA30-10-06626)/24.6 to 28.5Ω.

B Measure the impedances of the upper and lower heaters of the

reaction disk in the following procedures: Disconnect the connecting wire from J113 of the power patching

board. Measure the impedances of the upper and lower heater: upper

temperature-sensitive heater (BA30-10-06624)/437.8 to 483.8Ω, lower temperature-sensitive heater (BA30-10-06625)/131.4 to

145.2Ω.

7.8 Bar Code Scanner (optional) Failure

WARNING:

Light sent by the bar code scanner may hurt your eyes. Do not stare into the laser beam from the bar code scanner.

If the bar code scanner cannot emit laser , you can service it according to the fol lowing steps.

1 Place sample tubes with bar code labels that meet the requirements

mentioned in the operation manual.

2 Restart the analyzer.

7-9

Service Flow

3 Enter the Scanner Setup & Maintenance screen of the system software. 4 Enter the Maintenance tab. 5 Enter the sample position range in the Sample Position field and click the

If the bar code scanner emits laser normally but is failed in reading, you can service it according to the following steps.

1 Place the ANALYZING UNIT POWER to OFF. 2 Place sample tubes with bar code labels that meet the requirements

3 See if the window on the sample department is stained. If so, clean the

4 Restart the analyzer. 5 Enter the Scanner Setup & Maintenance screen of the system software.

Step Scan button. Observe if the scanner can emit laser. If not, click the Laser on button. If the scanner still cannot emit laser, go to the next step.

mentioned in the operation manual.

window with absolute alcohol-dipped gauze and go to the next step. If not, go to the step 8.

6 Enter the Maintenance tab. 7 Enter the sample position range in the Sample Position field and click the

Step Scan button. Observe the scanning procedures to see if the scanner

can read the bar codes. If not, go to the next step. 8 Enter the Setup tab. 9 Select all symbologies but do not select any Check or Length. 10 Enter the Maintenance tab. 11 Click the Scan button to see if the scanner can read the bar codes. If not,

go to the next step. 12 Place the test fixture to the position 28 on the sample disk. 13 Click the Mechanism button at the System Maintenance screen to reset

all mechanical parts. If the laser from the scanner cannot reach the bar

code through the slit on the test fixture, adjust the screws on the brackets

until the laser from the scanner can reach the bar code.

7-10

Bracket 1

Service Flow

Bracket 2

14 If the scanner cannot read the bar cod es successfully, replace the bar code

scanner. If the new scanner cannot read the bar code, you need to check

the bar code labels the user used.

7.9 Feeder Failure

7.9.1 Transducer Distribution of the Feeder

Pressure Transducer

No-Cuvette Transducer

Cuvette-Pushing Limit Transducer

Insufficient-Cuvette

Transducer

7-11

Cuvette-taking limit

transducer

Service Flow

7.9.2 Feeder Failure

Feeder failure

symptom

The trolley moves backward to the end, but does not move forward.

Possible causes:

The trolley moves forward and stops before compacting

the cuvette

segment

1. The cuvette-taking limit signal has not been detected.

2. The belt is too tight, so the motor cannot run. Troubleshooting:

1. Check whether the voltage is 0 when the cuvette-taking limit optical coupler is blocked.

2. Adjust the position of the motor to loosen the belt.

1. The moving resistance is too large, so the trolley fails to compact the cuvette segment, but the pressure transducer has been blocked.

2. The sliding block falls off, resulting in large friction.

3. The motor cannot work normally.

4. The belt is too tight. Troubleshooting:

1. Clean the guiding axis of the trolley.

2. Replace the sliding block assembly.

3. Replace the motor.

4. Loosen the belt.

The trolley keeps moving backward

and forward

1. The no-cuvette transducer has not been pressed completely, so the system deems that the cuvette compartment is empty, and the trolley moves back for cuvette segments. Troubleshooting:

1. Adjust the position of the no-cuvette transducer.

2. Replace the feeder assemblies.

7-12

7.9.3 Manipulator Failure

Manipulator vertical-

movement error:

Cannot reach/leave the

initial position.

The signal of the vertical optical coupler has not been detected after the motor runs for specified steps. Possible causes:

1. The resistance of the lead screw is too large (frequently).

2. The optical couplers for the vertical initial position cannot work (scarcely).

3. The vertical motor of the manipulator cannot work (scarcely).

4. The optical coupler connector is not connected well (infrequently).

5. The power driving board cannot work (infrequently).

6. The main control board cannot work (scarcely).

Service Flow

Troubleshooting:

1. Lubricate the lead screw after cleaning it.

2. Replace relevant

assemblies.

Manipulator

Failure

The upper hand of the manipulator cannot close/open. Direct cause:

The finger signal has

not been detected after

the electromagnet of

the manipulator is

switched on.

The lower hand of the manipulator cannot close/open. Direct cause: The finger signal has not been detected after the electromagnet of the manipulator is switched on.

The upper/lower hand of the manipulator accidentally closes/ opens. Direct cause: After the manipulator is

switched on, the finger

coupler signal is

received, but the signal

changes suddenly

while the manipulator

is moving.

1. The snap ring of the manipulator is not flexible (infrequently).

2. The coupler of the upper finger cannot work any more (scarcely).

3. The upper hand of the manipulator is not arranged well with the position of the feeder/reaction disk (frequently).

4. The coupler connector is not connected well (infrequently).

1. The operator has added too many cuvette segments into the feeder (behind the trolley). When the trolley moves backward, the jaw is pressed back by the cuvette segments; when it moves forward again, the hand fails to open in time, so the jaw may press one side of the trolley only. As a result, the cuvette segment at the front fails to corporate with the upper hand of the manipulator well (frequently).

2. The lower hand of the manipulator fails to corporate with the reaction disk position well (frequently).

3. The snap ring of the manipulator is not flexible (infrequently).

4. The lower hand coupler of the

manipulator cannot work any more

(scarcely).

1. The snap ring of the manipulator is not flexible (frequently).

2. The finger coupler of the manipulator cannot work any more (scarcely).

1. Adjust the positions of the upper hand and the feeder/ reaction disk.

2. Replace the

manipulator (Its

position must be

adjusted).

1. Press the cuvette-taking key after adding cuvette segments into the feeder.

2. Adjust the positions of the lower hand and reaction disk.

3. Replace the

manipulator (Its

position must be

adjusted)

Troubleshooting:

1. Replace the

manipulator (Its

position must be

adjusted).

7.10 Troubleshooting of ISE Unit (optional)

When there is something wrong with the ISE unit, an error code will be displayed at the screen and saved in the log. The error code of the ISE unit has a format of 7 ASCII characters, the format of which is <1234567>.

Each digit represents a certain error.

 Digit 1: Air in sample, Calibrant A, Calibrant B, Bubble Detector, mV range.  Digit 2: Sample/Calibrant B mV range.

7-13

Service Flow

 Digit 3: mV out of range for Calibrant A in Sample Cycle, or Calibrant B in Urine

 Digit 4: Noise in mV of Calibrant B in Calibration Cycle, or Sample mV during a

 Digit 5: mV Noise in Calibrant A of the Calibration Cycle, or Sample Cycle, mV

 Digit 6: mV Drift of calibrant A.  Digit 7: Slope of Sample value is out of range.

Each row represents where the error locates in. You can find all the seven numbers in the table below digit by digit and then know

what is wrong with the ISE unit. 0 means no error. For example, when you see <0001000>, you only need to find where the “1” locates

in the Digit 4 column and you will see it locates in the Na+ row. So you will know the cause of this error is the noise in mV of Calibrant B or sample related to the Na electrode.

Cycle.

Sample Cycle.

Noise in Calibrant B of the Urine Cycle.

Error

Digit 1 Digit 2 Digit 3 Digit 4 Digit 5 Digit 6 Digit 7

Air/ Hardwa re

mV Out Calib/S

ample

mV Out Cal A in

Calib/S ample Mode, Cal B in Urine Mode

mV Noise

Cal B/Samp le

mV Noise

Cal A in Calib/S ample Mode, Cal B in Urine

Cal A Drift

in Sample Mode, Cal B in Urine Mode

Out of Slope/ Machin e Ranges

Mode

Air in

S 0 0 0 0 0 0

Sample/Urine Air in Calibrant A A 0 0 0 0 0 0 Air in Calibrant B B 0 0 0 0 0 0 Air in Cleaner C 0 0 0 0 0 0 Air in Segment M 0 0 0 0 0 0 Pump Calibration P 0 0 0 0 0 0 No Flow F 0 0 0 0 0 0 Bubble Detector D 0 0 0 0 0 0 Reagent Chip

R 0 0 0 0 0 0

Read Reagent Chip

W 0 0 0 0 0 0

Write Store Calibration

Q 0 0 0 0 0 0

Value Error Command Error T 0 0 0 0 0 0 No Error 0 0 0 0 0 0 0 Na+ 0 1 1 1 1 1 1

7-14

Service Flow

Digit 1 Digit 2 Digit 3 Digit 4 Digit 5 Digit 6 Digit 7 Error

Air/ Hardwa re

K+ 0 2 2 2 2 2 2 Na+, K+ 0 3 3 3 3 3 3 Li+ 0 4 4 4 4 4 4 Li+, Na+ 0 5 5 5 5 5 5 Li+, K+ 0 6 6 6 6 6 6 Li+, K+, Na+ 0 7 7 7 7 7 7 Cl- 0 8 8 8 8 8 8

mV Out Calib/S

ample

mV Out Cal A in

Calib/S ample Mode, Cal B in Urine Mode

mV Noise

Cal B/Samp le

mV Noise

Cal A in Calib/S ample Mode, Cal B in Urine Mode

Cal A Drift

in Sample Mode, Cal B in Urine Mode

Out of Slope/ Machin e Ranges

Cl-, Na+ 0 9 9 9 9 9 9 Cl-, K+ 0 A A A A A A Cl-, Li+ 0 B B B B B B Cl-, K+, Na+ 0 C C C C C C Cl-, Li+, Na+ 0 D D D D D D Cl-, Li+, K+ 0 E E E E E E Cl-, Li+, K+, Na+ 0 F F F F F F

The following table displays the causes and the correction measures of some errors. Note that if the correction measure is the replacement of board, bubble detector or other components in the ISE unit, you have to replace the whole ISE unit. You can refer to the chapter 5 for detailed information about some replacement procedures.

Symptom Problem Correction

System does not respond

1. No power

2. Communication failure Turn off the system and then start it again.

3. RS232 cable is disconnected

or damaged.

4. Module connector has been

damaged.

5. Component failure on board. Replace board.

Move the panel of analyzing unit and reconnect or replace cable between the ISE unit and the main control board.

Replace board.

7-15

Service Flow

Symptom Problem Correction

Low Slope Na+, K+, or Li+ <45

mV/decade Cl- <35 mV/decade or High Slope Na+, K+, or Li+ >63

mV/decade Cl- >60 mV/decade

Noise Error Flag Single electrode

1. Misalignment of electrodes Remove and replace electrodes <45 mV/decade to reseat properly.

2. Deterioration of calibrator

solutions

3. Deterioration of sensing

electrode (low slope)

4. Air bubble on reference

electrode membrane

5. Deterioration of reference

electrode

6. Module or fluid temperatures

exceed 37° C. (high slope)

1. Deterioration of sensing

electrode

2. Electrical noise spike from

environmental source

Replace Calibrant B first and retest. If still low, replace Calibrant A and retest.

Replace problem electrodes and test.

Remove electrode, tap to dislodge bubble, replace, and recalibrate.

Replace reference electrode and retest.

Monitor temperature. Change instrument location if ambient is too great.

Replace problem electrodes and test.

a) Check for electrical noise coincident with activation.

Noise Error Flag Multiple electrodes

Drift Error Flag Single electrode

Drift Error Flag Multiple electrodes

1. Deterioration of reference

electrode

2. Electrical noise spike from

environmental source

1. May occur when new

electrode or new bottle of Calibrant A is installed by system.

2. Deterioration of sensing

electrode

1. May occur when new

electrode or new bottle of Calibrant A is installed on system.

b) Check grounding of Module. c) Component failure on Module

board. Replace board. Replace reference electrode

and retest. a) Check for electrical noise

coincident with activation. b) Check grounding of Module. c) Component failure on Module

board. Replace board. Purge the Calibrant A and

recalibrate the module. If the electrode is new it may initially drift as it rehydrates over the course of 15 minutes.

Replace the problem electrode and test.

Purge Calibrant A and recalibrate the Module.

2. Deterioration of reference

electrode.

7-16

Replace reference electrode and retest.

Symptom Problem Correction

Service Flow

3. Electrical spike from environmental source.

Air in Sample

Air in Sample and Calibrant A

1. Insufficient sample pipetted into Module sample entry port

2. Sample not positioned a) Electrodes not seated

1. Sample and Calibrant A are segmented with air.

a) Check for electrical noise coincident with activation.

b) Check grounding of Module. c) Component failure on Module

board. Replace the board. a) Host instrument must deliver

70 µL. Increase dispensed volume.

b) Operator must place sufficient sample in sample cup to account for all tests programmed.

c) Fluid leak in electrodes.

properly. Reseat electrodes. b) Pump tubing aging. Replace. c) Pump tubing obstructed or

tubing length is excessive. a) Electrodes are not properly

seated or compressed. Check compression plate, spring and seal. Reseat electrodes.

Air in Calibrant B and Air in Calibrant A

b) Ensure that all electrodes and o-rings are in place.

2. Fibrin or salt is plugging the electrode flow path.

3. Bubble detector is malfunctioning.

4.Waste pump is malfunctioning.

1. Calibrant B and Calibrant A are segmented with air.

a) Use Cleaning procedure for Module.

b) Disassemble Module and clean or replace electrode with plugged flow path.

Replace bubble detector.

Replace waste pump.

a) Electrodes are not properly compressed. Check compression plate, spring and seal.

b) Ensure that all electrodes and o-rings are in place.

c) Ensure tubing is connected properly.

d) Replace tubing.

7-17

Service Flow

Symptom Problem Correction

Air in Calibrant A (no “Air” errors reported for Sample or Calibrant B)

2. Fibrin or salt is plugging the electrode flow path.

3. Waste pump malfunction. Replace waste pump, tubing.

4. Bubble Detector malfunction. Replace bubble detector.

1. Calibrant A pouch is empty. Replace Calibrant A with a new

2. Tubing is disconnected. Reconnect or replace tubing.

3. Calibrant A pump is not working properly.

4. Tubing is plugged, split or crimped.

a) Use Cleaning procedure for Module.

b) Disassemble Module and clean or replace electrode with plugged flow path.

one, purge and recalibrate.

a) Check electrical connections. b) Replace pump tubing. c) Replace motor. Replace tubing

7-18

8 Mechanical Structure

Synchronous belts

Coder sensors

Mechanical Structure

Reaction disk motor Reagent disk motor

8-1

Mechanical Structure

Reagent probe assembly

Sample probe assemblyMixing bar assembly

Reagent cooling assembly

8-2

Lamb assembly

Mechanical Structure

Big head of fiber

Fan of Lamb assembly

8-3

Mechanical Structure

Optical assembly

Reaction disk TEMP.

control assembly

Small heads of fiber

Reference light assembly

8-4

Mechanical Structure

Reagent syringe

Washing assemblies

Sam

le syringe

alves

Pumps

8-5

Mechanical Structure

A/D conversion board

Main control board Power drive board

Reagent refrigeration board

8-6

Mechanical Structure

Loading system

Manipulator

assembly

8-7

Mechanical Structure

Top of mixing assembly

Top of sample assembly

Top of reagent assembly

Bar code scanner (optional)

8-8

Tools and Parts

9 Tools and Parts

9.1 Service Tools

S/N TOOL Quantity Specification Unit

1 Allen Key 1 set 1.5, 2.0, 2.5, 3.0, 3.5,

4.0, 5.0 2 Phillips screwdriver 1 set 3*75, 5*75, 6*100 mm 3 Flat-bladed screwdriver 1 set 3*75, 5*75, 6*100 mm 4 Long Allen Key 1 set 2.5, 3.0 mm 5 Tweezers 1 pair small / 6 Multimeter 1 common / 7 Movable Wrench 1 common /

8 Electric iron 1 30 VA 9 Stainless steel 1 0.5 (diameter), 15

(length) 10 Knife 1 common / 11 Pincers 1 common /

9.2 Parts

S/N P/N Name

1 BA30-20-06448 Cable for reagent probe assembly’s elevator motor 2 BA30-20-06449 Cable for reagent probe assembly’s rotary motor 3 BA30-20-06450 Cable for Sample syringe’s motor 4 BA34-20-63601 Cable for Reagent syringe’s motor 5 BA30-20-06452 Cable for sample probe assembly’s elevator motor 6 BA30-20-06453 Cable for sample probe assembly’s rotary motor 7 BA30-20-06454 Cable for mixing bar assembly’s rotary motor

8 BA30-20-06455 Cable for mixing bar assembly’s elevator motor 9 BA30-20-06458 Cable for reagent compartment motor

10 BA30-20-06459 Cable for sample compartment motor

11 BA34-20-63602 Cable for reaction compartment motor 12 BA30-20-06464 Cable for loading system motor 13 BA30-20-06468 Cable for Sample and reagent valves

9-1

Tools and Parts

S/N P/N Name

14 BA30-20-06476 26-pins sensor cable 15 BA30-20-06477 34-pins sensor cable 16 BA30-20-06480 Detection cable for reaction compartment’s fan 17 BA30-20-06481 Cable between CPU board and power drive board 18 BA30-20-06484 Cable for waste and distill water container 19 BA30-20-06485 Cable between CPU board and loading system 20 BA34-20-63651 Cable between CPU board and manipulator 21 BA30-20-06523 T emperature sensor cable of reagent cooling system 22 BA30-20-15291 Cable between CPU board and reagent detection board 23 BA30-20-15292 Cable between CPU board and sample detection board 24 BA34-20-63603 Cable between power drive board and mixing motor 25 BA34-20-63631 Reagent probe cable 26 BA30-20-15295 Sample probe cable 27 BA30-20-15296 Mixing bar cable 28 A21-000010--- Tubing 29 BA30-10-15051 Single-way valve 30 0040-10-32303 Tubing 31 0040-10-32304 Connector 32 0040-10-32305 Connector 33 M90-100014--- 1/4-28 UNF LOCK NUT-RED NYL LNS-3 34 M90-100015--- 1/4-28 UNF LOCK NUT-RED N NYL LNS-4 35 M90-100030--- 1/8 Y BARBED FITTING-WHITE NYL Y23036

M90-100050---

M90-100051--38 M90-100071--- Tubing 39 BA30-30-15169 5-way connector 40 BA30-10-06666 Step motor

BULKHEAD MOUNTED FEMALE LURE RED NYLON CCLR-3

BULKHEAD MOUNTED FEMALE LURE GREEN NYLON CCLR-4

41 BA30-10-15041 synchronous belt (220 XL037) 42 BA30-10-15258 Door’s magnet (couple) 43 BA34-30-63559 Power drive board 44 BA30-30-06312 Reagent cooling control board 45 BA34-30-63613 Sample compartment assembly

9-2

Tools and Parts

S/N P/N Name

46 BA30-10-06365 Halogen Lamb (50W) 47 BA30-30-06691 REF pre-amplification board 48 BA30-30-15228 340nm amplification assembly 49 BA30-10-06367 Filter 340 50 BA30-30-06673 340nm pre-amplification board 51 BA30-30-15229 405nm pre-amplification assembly 52 BA30-10-06368 Filter 405 53 BA30-30-06675 405 pre-amplification board 54 BA30-30-15230 450nm pre-amplification assembly 55 BA30-10-06369 Filter 450 56 BA30-30-06677 450 pre-amplification board 57 BA30-30-15231 510nm pre-amplification assembly 58 BA30-10-06370 Filter 510 59 BA30-30-06679 510 pre-amplification board 60 BA30-30-15232 546nm pre-amplification assembly 61 BA30-10-06371 Filter 546 62 BA30-30-06681 546 pre-amplification board 63 BA30-30-15233 578nm pre-amplification assembly 64 BA30-10-06372 Filter 578 65 BA30-30-06683 578 pre-amplification board 66 BA30-30-15234 630nm pre-amplification assembly 67 BA30-10-06373 Filter 630 68 BA30-30-15235 630 pre-amplification board 69 BA30-30-15235 670nm pre-amplification assembly 70 BA30-10-06374 Filter 670 71 BA30-30-06687 670 pre-amplification board 72 BA30-30-15236 700nm pre-amplification assembly 73 BA30-10-06375 Filter 700 74 BA30-30-06689 700 pre-amplification board 75 BA30-30-06565 Drive assembly of sample probe 76 BA34-30-63637 Syringe assemply 77 3100-10-49438 100ul Syringe 78 BA30-10-06651 500ul Syringe 79 BA30-10-15115 Step motor

9-3

Tools and Parts

S/N P/N Name

80 BA30-20-06594 3-way connector for syringe 81 BA30-21-15161 Sensor cable for reagent syringe 82 BA30-21-15162 Sensor cable for sample syringe 83 BA30-30-06634 Mixing bar assembly 84 BA30-21-15159 Cable for mixing bar assembly’s elevator motor 85 BA30-21-15160 Cable for mixing bar assembly’s rotary motor 86 BA30-30-06639 Fans of lamb assembly 87 BA30-30-06641 Washing pool assembly 88 0040-10-32302 Connector 89 0040-10-32303 Washer 90 BA30-21-15311 Valves assembly (KNF) 91 BA30-30-06702 Reaction compartment assembly 92 BA30-30-06715 A/D converter assembly 93 BA30-30-06752 Rocker of reagent probe 94 BA30-30-06304 Liquid detection board 95 BA30-30-06753 Reagent probe assembly 96 BA30-30-06761 Heat-block assembly 97 BA30-30-06768 Rocker of sample probe 98 BA30-30-14978 Sample probe assembly 99 BA30-30-06770 Rocker of mixing bar

100 BA34-20-63653 Loading system assembly 101 BA30-21-06488 Pressure sensor and cable for loading system 102 BA30-21-06490 Cable for cuvette-pushing limit transducer 103 BA30-21-06491 Cable for cuvette-taking limit transducer 104 BA30-21-06492 Cable for insufficient-cuvette transducer 105 BA34-20-63648 Board for loading system 106 BA30-21-06489 Cable for no-cuvette transducer 107 BA30-30-15034 Code sensor of reaction compartment 108 BA30-30-15095 Reagent compartment assembly 109 BA30-30-06780 Reagent disk handle assembly 110 BA30-30-15113 Driving assembly of reagent probe

111 BA30-21-15155 Sensor cable for reagent probe’s up-down sensor

112 BA30-21-15156 Sensor cable for reagent probe’s rotary sensor 113 BA30-30-15166 Coder sensor for reagent disk

9-4

Tools and Parts

S/N P/N Name

114 BA30-30-15167 Coder sensor for sample probe’s sensor 115 BA30-30-15284 Probes connection board 116 BA34-30-63557 Main control board 117 BA33-30-35098 Power supply module 118 BA33-30-35078 PFC Board 119 BA33-30-35082 24V Board 120 BA33-30-35080 12V&5V Board 121 TSB1-20-20399 Fan 122 BA34-20-63655 Manipulator assembly 123 BA33-30-35223 Power socket and switch assembly 124 BA34-20-63622 Reagent temperature control assemply (220V) 125 BA34-20-63614 Cover of sample compartment 126 BA30-30-15029 Cover of reagent compartment 127 BA34-20-63638 Reagent temperature control assemply (110V)

9-5

Maintenance And T est Software

10 Maintenance And Test Software

10.1 General

The maintenance and test software of the BS-300 Chemistry Analyzer is the

software that helps maintenance personnel debug and maintain the BS-300

Chemistry Analyzer. Maintenance personnel can, through this software, check

whether the probes, mixing bar, disks, fluidic system and photometric system of

the BS-300 Chemistry Analyzer work normally, modify parameters, and execute

individual commands or combined commands.

Run the NewDebug.exe file to enter the Maintenance and Test window. See

Figure 10-1.

Figure 10-1 Maintenance and Test window

Display Area

As shown in Figure 10-1, there are 4 tabs in the Maintenance and Test window:

 Command

 PARA and Speed

 Temperature

 Photoelectric

10-1

Maintenance And T est Software

Note:

The buttons displayed in gray in software interface are not functional.

Following is a brief introduction to the software interface.

 Display area

At the bottom of the window is the display area for displaying the frame

information and fault/error information. The upper box is for frame information, and

the lower one is for fault/error information.

There are five types of frame information, including Result, Echo, Data,

Command and Warning.

Select the check box in front of frame information to display relevant frame

information. Click the check box again to de-select, and the frame information will

not be displayed.

Click the Clear button to clear the information displayed in relevant box. The two

Clear buttons are respectively for two boxes.

 Setup button

Click the Setup button at up right corner to show a dialog as shown in Figure 10-2,

which is used to change communication port and set baud rate and check sum

type of the port. Check sum type includes odd, even and none.

Figure 10-2 Serial Port Setup

Communication Port

Baud Rate

Check Sum Type

 About… button

Clicking the About… button at up right corner of the interface, you can view the

version information of this software.

In the following sections, the 4 tabs mentioned above will be detailed respectively.

10-2

Note:

The units of parameters involved in this software are respectively: Time: 50ms; Sample (reagent) aspirating/dispensing volume: steps of motors; Temperature: ℃. Temperature control coefficient: 0.01.

10.2 Command

In the Command tab, you can send commands to the analyzing unit and check

whether probes, mixing bar, disks, fluidic system, photometric system, ISE unit

and built-in bar code scanner work normally.

Figure 10-3 Command tab

Maintenance And T est Software

Single Command Area

As shown in Figure 10-3, the Command tab mainly consists of two parts: Single

Command Area and Macroinstruction Area.

Macroinstruction Area

10.2.1 Single Command Area

In Single Command Area, there are 8 sub-tabs:

 Main Unit

 Reagent Unit

 Sample Unit

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Maintenance And T est Software

 Load Unit

 Temp Unit

 Photoelectric Unit

 ISE Module

 Sample Bar Code Module

Check the analyzing unit for their counterparts.

There are several buttons in each tab. Click a button and you can send a

command to the counterpart on the analyzing unit.

Note:

After starting this software, you must click the Download

parameters to Analyzing Unit button in the Main Unit sub-tab.

Otherwise, the software will not operate the analyzing unit successfully.

After clicking the Enable modifying parameters button in the Main

Unit sub-tab, you can modify the parameters in the PARA and Speed tab.

Following are instructions to the action implemented by each command.

 Main Unit

Command What it does

Download parameters to Analyzing Unit

Reset all mechanical parts Moves all units of the analyzing unit to their

Enable modifying parameters

Disable modifying parameters

Handshake with Analyzing Unit

Send a direct instruction Edits and sends user-defined commands.

Configures running parameters for the analyzing unit.

initial position, and cleans reagent probe, sample probe and mixing bar.

Switches on the switch for modifying parameter through this operation before modifying parameter at PARA and Speed tab.

Switches off the switch for modifying parameter through this operation after modifying parameter at PARA and Speed tab.

Checks that the communication cable works normally.

 Reagent Unit

Command What it does

Reagent probe wash Cleans the reagent probe. Pump, valve (interior) on Turns on the pump and the valves that control

flow of washing the interior of reagent probe.

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Command What it does

Pump, valve (interior) off Turns off the pump and the valves that control

flow of washing the interior of reagent probe.

Pump, valve (exterior) on Turns on the pump and the valve that control

flow of washing the exterior of reagent probe.

Pump, valve (exterior) off Turns off the pump and the valve that control

flow of washing the exterior of reagent probe.

Probe above reaction disk Moves the reagent probe above the reaction

disk.

Probe above outer circle Moves the reagent probe above the outer circle

of reagent disk.

Probe above inner circle Moves the reagent probe above the inner circle

of reagent disk.

Probe tip above bottle top (outer circle)

Probe tip above bottle top (inner circle)

Probe down to outer circle Moves the reagent probe down to the reagent

Probe down to inner circle Moves the reagent probe down to the reagent

Probe down to reaction disk Moves the reagent probe down to the cuvette

Probe tip above cuvette top Moves the reagent probe until the probe tip a

Probe down to wash well Moves the reagent probe to its washing

Probe above wash well Moves the reagent probe to the top of wash

Reagent disk rotate Rotates the reagent disk for specified circles

Moves the reagent probe until the probe tip a few millimeters above the top of the reagent bottle in the outer circle of reagent disk.

Moves the reagent probe until the probe tip a few millimeters above the top of the reagent bottle in the inner circle of reagent disk.

bottle in the outer circle of reagent disk.

bottle in the inner circle reagent disk.

in the reaction disk.

few millimeters above the top of cuvette in the reaction disk.

position.

well.

and stop it at specified bottle position. Input rotating circles in the first box and position No. in the second box.

Reagent disk rotate to position

Reagent syringe init Moves the reagent syringe to its initial position. Reagent syringe full Moves the reagent syringe to its largest travel. Reagent syringe empty Empties the reagent syringe. Reagent unit reset Cleans the reagent probe and rotates the

Rotates the reagent disk to specified bottle position. Input position No. in the box.

reagent disk to position No. 1.

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 Sample Unit

Command What it does

Sample probe wash Cleans the sample probe. Pump, valve (interior) on Turns on the pump and the valves that control

Pump, valve (interior) off Turns off the pump and the valves that control

Pump, valve (exterior) on Turns on the pump and the valve that control

Pump, valve (exterior) off Turns off the pump and the valve that control

Probe above wash well Moves the sample probe to the top of wash

Probe above reaction disk Moves the sample probe to the top of reaction

Probe above outer circle Moves the sample probe above the outer circle

flow of washing the interior of sample probe.

flow of washing the exterior of sample probe.

well.

disk.

of sample disk.

Probe above inner circle Moves the sample probe above the inner circle

of sample disk.

Probe tip above tube top (outer circle)

Probe tip above tube top (inner circle)

Probe tip above cuvette top Moves the sample probe until the probe tip a

Probe down to reaction disk Moves the sample probe down to the reaction

Probe down to wash well Moves the sample probe to its washing

Probe down to outer circle Moves the sample probe down to the tube in

Probe down to inner circle Moves the sample probe down to the tube in

Sample disk rotate Rotates the sample disk for specified circles

Moves the sample probe until the probe tip a few millimeters above the top of the tube in the outer circle of sample disk.

Moves the sample probe until the probe tip a few millimeters above the top of the tube in the inner circle of sample disk.

few millimeters above the top of cuvette in the reaction disk.

cuvette in reaction disk.

position.

the outer circle of sample disk.

the inner circle of sample disk.

and stop it at specified tube position. Input rotating circles in the first box and position No. in the second box.

Sample disk rotate to position

Sample syringe init Moves the sample syringe to its initial position. Sample syringe empty Empties the sample syringe. Sample syringe full Moves the sample syringe to its largest travel.

Rotates the sample disk to specified tube position. Input position No. in the box.

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Maintenance And T est Software

Command What it does

Sample unit reset Cleans the sample probe and rotate the sample

disk to position No. 1.

 Load Unit

Command What it does

Mixer to the top of wash well Moves the mixing bar to the top of wash well. Mixer move into wash well Moves the mixing bar to its washing position.

Mixer move to the top of reaction disk

Mixer move into reaction disk

Mixer stir for a while Mixing bar stirs for a specified period. Mixing bar rotates for a while

above wash well Take new cuvettes Moves the compartment trolley backwards to

Load New cup Rotates the reaction disk to specified position,

Unload cup Rotates the reaction disk to specified position,

Motion of manipulator fingers Tightens or loosen manipulator’s fingers

Moves the mixing bar to the top of reaction disk.

Moves the mixing bar to mixing position in reaction disk.

Moves the mixing bar above its wash well and then rotates it for a specified period.

get new cuvettes.

then get new cuvettes with the manipulator and put them in reaction disk.

then get the cuvettes in reaction disk with the manipulator and put them in used-cuvette bucket.

(grabbing mechanism). After entering a value of 0-3 to the box, click

the button and the fingers will motions. 0 means both fingers tighten; 1 means the upper loosen and the lower tightens; 2 means the upper tightens and the lower loosens; and 3 means both loosen.

Manipulator to vertical init. pos.

Manipulator to horiz. init. pos.

To H-pos. for taking cuvettes Moves the manipulator to horizontal position for

To V-pos. for taking cuvettes Moves the manipulator to vertical position for

To H-position for placing cuvettes

To V-position for placing cuvettes

Moves the manipulator to vertical initial position.

Moves the manipulator to horizontal initial position.

getting cuvettes.

getting cuvettes. Moves the manipulator to horizontal position for

placing cuvettes. Moves the manipulator to vertical position for

placing cuvettes.

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Maintenance And T est Software

Command What it does

Move steps vertically Moves the manipulator for specified steps in

Move steps horizontally Moves the manipulator for specified steps in

Loader unit reset Moves the mixing bar to its initial position,

 Temp Unit

Command What it does

Temperature control on Turns on the specified temperature

vertical way.

horizontal way.

loosen manipulator’ grabbing mechanism and move the manipulator to its initial position.

controller(s). There’re two temperature controllers as

Reaction Disk and Reagent PreHeat. Selects the check box(es) in front of a

controller(s), click the button, you can turn on the selected controller(s).

Temperature control off Turns off the specified temperature

controller(s). There’re two temperature controllers as

Reaction Disk and Reagent PreHeat. Selects the check box(es) in front of a

controller(s), click the button, you can turn off the selected controller(s).

 Photoelectric Unit

Command What it does

Reaction disk rotate Rotates the reaction disk for specified circles

and stop it at specified cuvette position. Input rotating circles in the first box and position No. in the second box.

Reaction disk rotate some positions

Rotate and measure Rotates the reaction disk, collects reaction data

Rotates the reaction disk for specified cuvette positions, and input number of cuvette positions in the box.

during rotating, and then stops it at specified

cuvette position. Turn on light Turns on the light. Turn off light Turns off the light. Test dark current Turns off the light and measures the dark

current at this time. The dark current data will

be displayed in the box below.

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Maintenance And T est Software

Command What it does

Test base current Unloads the first segment of cuvettes in

reaction disk with manipulator, then rotates the

reaction disk and during rotating measures the

light where places the first segment of cuvettes

before. The data regarding base current will be

displayed in the box below.

 ISE Module

Command What it does

Handshake The ISE unit shakes hands with the main unit. Maintain Executes the maintaining cycle to run the waste pump until

the electrode flow path is cleared of fluid.

Detect Bubble Checks to see if the bubble detector is functioning

properly. Cleaning Period Removes protein build-up from the ISE Module electrodes. Calibrate Calibrates the electrodes of the ISE Module. Correct Pumps Calibrates the peristaltic pumps of the ISE Module. Measure Serum Measures serum or plasma samples on the ISE Module. A Purge Purges Calibrant A solution through the tubing from the

pouch of Calibrant A to the ISE Module. B Purge Purges Calibrant B solution through the tubing from the

pouch of Calibrant B to the ISE Module. <DSPA> Pumps 200µl of Calibrant A to make it convenient for you

to aspirate it from the sample entry port. <SWBC> Displays the result of bubble detector checking for the last

time. <SWPC> Displays the result of pump correction for the last time. <CKSM> Displays the software version of the ISE unit. <DVON> After clicking this button, the results in mv will also be

displayed when calibration, measurement or a sip cycle is

finished. <MVON> After clicking this button, the results in mv will also be

displayed when calibration or measurement is finished. <DVFF> Disables the effect of clicking <DVON> or <MVON>.

 Sample Bar Code Module

Command What it does

Set Select a symbology from the pull down list and click this

button. If Valid is selected, the symbology will be set as the one that the scanner can recognize. Otherwise, it will be the one that can not be recognized.

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Maintenance And T est Software

Command What it does

Send Enter an instruction into the edit box and click this button to

send it to the analyzing unit. Laser On Turns on the laser of the bar code scanner. Laser Off Turns off the laser of the bar code scanner. Handshake The bar code scanner shakes hands with the main unit. Scan After entering the start position No. and the end one into

Start and End edit boxes respectively, click this button to

scan bar codes on the selected positions.

10.2.2 Macroinstruction Area

Figure 10-4 Macroinstruction Area

Button

Parameters of the current command

Explanation for the

macroinstruction

Macroinstruction

Commands

A macroinstruction is a set of commands. When selecting a macroinstruction from the pulldown list in macroinstruction area,

you can see there’re various commands and comments regarding the macroinstruction. In addition, parameters of the command currently selected will also be displayed on the interface.

In the macroinstruction area, after selecting a macroinstruction from the pulldown list, you can

 Click the Run button to run the selected macroinstruction;

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 Click the Pause button to suspend the macroinstruction which is running;  Click the Stop button to stop the macroinstruction which is running.

Note:

After all commands in each macroinstruction are executed, the system counts it as one time.

When the check box on the right of the macroinstruction pulldown list is selected, the selected macroinstruction will be executed for once; otherwise, the macroinstruction will be executed cyclically.

For each macroinstruction, the commands of it are executed one by one in the sequence in which they are listed. When the set delay expires after a command is executed, the next command is executed immediately. In case of an error in the execution process, the macroinstruction will be stopped.

Following are instructions to the action implemented by each macroinstruction.

Macroinstruction Command What it does

A,B purge

B purge Purges Calibrant B solution

through the tubing from the pouch of Calibrant B to the ISE Module.

Check exterior fluid path of reagent probe

Check exterior fluid path of sample probe

A purge Purges Calibrant A solution

through the tubing from the pouch of Calibrant A to the ISE Module.

Reagent probe above wash well

Valve on, Pump on Turns on the pump and valve

Pump off, Valve off Turns off the pump and valve

Sample probe above wash well

Valve on, Pump on Turns on the pump and valve

Pump off, Valve off Turns off the pump and valve

Moves the reagent probe above its wash well.

that control the flow of washing the exterior of reagent probe.

Moves the sample probe above its wash well.

that control the flow of washing the exterior of sample probe.

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Maintenance And T est Software

Macroinstruction Command What it does

Check interior fluid path of reagent probe

Reagent probe above wash well

Valve on, Pump on Turns on the pump and

Pump off, Valve off Turns off the pump and

Moves the reagent probe above its wash well.

valves that control the flow of washing the interior of reagent probe.

Check interior fluid path of sample probe

Test Loader Reload cup looply The manipulator gets new

Test mixing bar in reaction disk

Sample probe above wash well

Valve on, Pump on Turns on the pump and

Pump off, Valve off Turns off the pump and

Reaction disk to next cup

Mix instruction The mixing bar moves into

Mixer to vertical init The mixing bar moves to

Moves the sample probe above its wash well.

valves that control the flow of washing the interior of sample probe.

cuvettes from the compartment looply, and then put them in the reaction disk.

The reaction disk rotates and stops. No. of position for reaction disk to stop at will increase.

reaction cuvette and mixes for a specified period.

vertical initial position.

Test reagent probe in reaction disk

Test sample probe in reaction disk

Reaction disk to next cup

Reagent probe to reaction disk

Reagent probe to vertical init

Reaction disk to next cup

10-12

The reaction disk rotates and stops. No. of position for reaction disk to stop at will increase.

The reagent probe moves vertically into bottom of reaction cuvette.

The reagent probe moves to vertical initial position.

The reaction disk rotates and stops. No. of position for reaction disk to stop at will increase.

Maintenance And T est Software

Macroinstruction Command What it does

Sample probe to reaction disk

The sample probe moves vertically into bottom of reaction cuvette.

Urine test (auto diluted)

Sample probe to vertical init

Reagent disk in position 50 in next period

Dispensing 270µl of urine diluent

Dispensing 30µl of urine sample

Washing mixing bar Washes the mixing bar. First period Sample probe aspirates 70µl

Second period Sample probe aspirates 70µl

The sample probe moves to vertical initial position.

Reagent disk rotates to position 50 and in the next period the reagent probe will aspirate urine diluent from the position.

Reagent probe aspirates 207µl of urine diluent and dispenses it to a cuvette.

Sample probe aspirates 30µl of urine sample and dispenses it to a cuvette. The mixing bar stirs it.

of diluted urine to the ISE unit.

Urine test (manually diluted)

10.3 PARA and Speed

Third period Washes the sample probe. Idle period Measuring. Idle period Measuring. Idle period Measuring. First period Sample probe aspirates 70µl

of diluted urine to the ISE unit.

Second period Sample probe aspirates 70µl

of diluted urine to the ISE

unit. Third period Washes the sample probe. Idle period Measuring. Idle period Measuring. Idle period Measuring.

In the PARA and Speed tab, you can query, configure or load parameters as well as debug the units.

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Figure 10-5 PARA and Speed tab

Parameters

As shown in Figure 10-5, the PARA and Speed tab mainly consists of two parts as unit parameter and several operating buttons.

Buttons

Unit Name includes Main unit, Sample unit, Reagent unit, Photoelectric unit, Temp unit and Load unit.

At this screen, you can not only inquire and configure each unit parameters, but also save and read relevant data. Now let’s introduce them respectively.

 Inquire unit parameters

1 Select a unit in Unit Name. 2 Click Query button.

For example.

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Maintenance And T est Software

 Configure a parameter for a unit

1 Select a unit in Unit Name. 2 Click the Query button. 3 Edit the parameter if necessary. Otherwise, go to the next step directly.

When editing, you can directly select and modify the data to be edited.

4 Select a parameter to be configured. For example.

5 Click the Config button to configure the parameter for relevant unit of the

analyzing unit.

 Configure all parameters for relevant units

1 Select units in Unit Name. 2 Click the Config All button to configure all parameters of the selected unit

for relevant units of the analyzing unit.

 Save data

1 Select a unit in Unit Name. 2 Click the Save button, then pop up a dialog. 3 Input a filename and click the Save button, you can save parameters of the

currently selected unit to a .txt file.

 Read Data

1 Click Load button, then pop up a dialog. 2 Select the relevant .txt file and click Open button, you can configure

parameters in the file for relevant unit of the analyzing unit.

The following contents explain the adjustable parameters.

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 Reagent unit

Parameter Unit Default What the parameter m eans

H-pos. for washing reagent probe

Whole step

42 Position correction of the

reagent probe in the horizontal direction when it is above its wash well.

H-pos. of reaction disk Whole

step

H-pos. of reagent disk inner circle

H-pos. of reagent disk outer circle

Position correction of reagent disk inner circle

Position correction of reagent disk outer circle

Whole step

Micro step

-42 Position correction of the reagent probe in the horizontal direction when it is above the reaction disk.

215 Position correction of the

reagent probe in the horizontal direction when it is above the inner circle of reagent disk.

165 Position correction of the

reagent probe in the horizontal direction when it is above the outer circle of reagent disk.

10 The position correction of the

reagent disk when it stops at the specified position according to the position No. of its inner circle.

10 The position correction of the

reagent disk when it stops at the specified position according to the position No. of its outer circle.

 Sample unit

Parameter Unit Default What the parameter means

Bar code position correction of sample disk inner circle

H-pos. for washing sample probe

H-pos. of sample disk inner circle

H-pos. of sample disk outer circle

Micro step

Whole step

18 Position correction of the inner

circle of sample disk relative to the outer circle when the bar code scanner scans specified positions.

102 Position correction of the

sample probe in the horizontal direction when it is above its wash well.

202 Position correction of the

sample probe in the horizontal direction when it is above the inner circle of sample disk.

165 Position correction of the

sample probe in the horizontal direction when it is above the outer circle of sample disk.

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Maintenance And T est Software

Parameter Unit Default What the parameter means

H-pos. of sample probe in reaction disk

Whole step

-106 Position correction of the sample probe in the horizontal direction when it is above the reaction disk.

H-pos. of sample probe in ISE

Position correction of sample disk inner circle

Position correction of sample disk outer circle

V-pos. of sample probe in ISE

Whole step

Micro step

Whole step

490 Position correction of the

sample probe in the horizontal direction when it is above the sample entry port of ISE unit.

10 The position correction of the

sample disk when it stops at the specified position according to the position No. of its inner circle.

10 The position correction of the

sample disk when it stops at the specified position according to the position No. of its outer circle.

163 Position correction of the

sample probe in the vertical direction when it is above the sample entry port of ISE unit.

 Load unit

Parameter Unit Default What the parameter means Manipulator h-position

for placing cuvettes

Whole step

70 Position correction of the

manipulator in horizontal direction when it places a cuvette segment into the reaction disk.

Manipulator h-position for taking cuvettes

Manipulator v-position for placing cuvettes

Manipulator v-position for taking cuvettes

Mixing bar h-position for washing

Whole step

259 Position correction of the

manipulator in horizontal direction when it takes a cuvette segment from the cuvette compartment.

70 Position correction of the

manipulator in vertical direction when it places a cuvette segment into the reaction disk.

768 Position correction of the

manipulator in vertical direction when it takes a cuvette segment from the cuvette compartment.

68 Position correction of the

mixing bar in the horizontal direction when it is above its wash well.

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Parameter Unit Default What the parameter means Mixing bar h-position

for mixing

 Photoelectric unit

Parameter Unit Default What the parameter means Photoelectric gain

parameter 405

Whole step

/ 127 Signal gain coefficient of A/D

70 Position correction of the

mixing bar in horizontal direction when it is above the reaction disk.

conversion for wavelength of 405nm.

Photoelectric gain parameter 450

Photoelectric gain parameter 510

Photoelectric gain parameter 546

Photoelectric gain parameter 578

Photoelectric gain parameter 630

Photoelectric gain parameter 670

Photoelectric gain parameter 700

/ 127 Signal gain coefficient of A/D

conversion for wavelength of 450nm.

conversion for wavelength of 510nm.

conversion for wavelength of 546nm.

conversion for wavelength of 578nm.

conversion for wavelength of 630nm.

conversion for wavelength of 670nm.

conversion for wavelength of 700nm.

Photoelectric gain parameter reference light

Photoelectric gain parameter 340

Start position of photoelectric collection

/ 127 Signal gain coefficient of A/D

Micro step

conversion for wavelength of reference light.

conversion for wavelength of 340nm.

25 Correction of the start position

when photoelectric collection starts.

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MINDRAY BS 300 Service Manual

Specifications and Main Features

Frequently Asked Questions

User Manual