SHENZHEN MINDRAY
Mindray) owns all rights to this unpublished work and intends to maintain this work as
confidential. Mindray may also seek to maintain this work as an unpublished copyright.
This publication is to be used solely for the purposes of reference, operation, maintenance,
or repair of Mindray equipment. No part of this can be disseminated for other purposes.
BIO-MEDICAL ELECTRONICS CO., LTD. 2003
®
BIO-MEDICAL ELECTRONICS CO., LTD. (hereinafter called
In the event of inadvertent or deliberate publication, Mindray intends to enforce its rights to
this work under copyright laws as a published work. Those having access to this work may
not copy, use, or disclose the information in this work unless expressly authorized by
Mindray to do so.
All information contained in this publication is believed to be correct. Mindray shall not be
liable for errors contained herein nor for incidental or consequential damages in
connection with the furnishing, performance, or use of this material. This publication may
refer to information and protected by copyrights or patents and does not convey any
license under the patent rights of Mindray, nor the rights of others. Mindray does not
assume any liability arising out of any infringements of patents or other rights of third
parties.
Content of this manual is subject to changes without prior notice.
PROPERTY OF
®
SHENZHEN MINDRAY
BIO-MEDICAL ELECTRONICS CO., LTD.
ALL RIGHTS RESERVED
Responsibility on the manufacturer party
Mindray is responsible for safety, reliability and performance of this equipment only in the
condition that:
Auto Hematology Analyzer Service Manual (V1.1) i
•
all installation, expansion, change, modification and repair of this equipment are
conducted by Mindray qualified personnel;
•
applied electrical appliance is in compliance with relevant National Standards;
•
the instrument is operated under strict observance of this manual.
Note
This equipment is not intended for family usage.
This equipment must be operated by skilled/trained clinical personnel.
Warning
It is important for the hospital or organization that employs this equipment to carry out a
reasonable maintenance schedule. Neglect of this may result in machine breakdown or
injury of human health.
Upon request, Mindray may provide, with compensation, necessary circuit diagrams,
calibration illustration list and other information to help qualified technician to maintain and
repair some parts, which Mindray may define as user serviceable.
ii Auto Hematology Analyzer Service Manual (V1.1)
Warranty
Workmanship & Materials
Mindray guarantees new equipment other than accessories to be free from defects in
workmanship and materials for a period of one year from date of shipment under normal
use and service. Mindray's obligation under this warranty is limited to repairing, at
Mindray’s option, any part which upon Mindray's examination proves defective.
THIS WARRANTY IS EXCLUSIVE AND IS IN LIEU OF ALL OTHER WARRANTIES,
EXPRESSED OR IMPLIED, INCLUDING WARRANTIES OF MERCHANT ABILITY OR
FITNESS FOR ANY PARTICULAR PURPOSE.
Exemptions
Mindray's obligation or liability under this warranty does not include any transportation or
other charges or liability for direct, indirect or consequential damages or delay resulting
from the improper use or application of the product or the substitution upon it of parts or
accessories not approved by Mindray or repaired by anyone other than a Mindray
authorized representative.
This warranty shall not extend to any instrument which has been subjected to misuse,
negligence or accident; any instrument from which Mindray's original serial number tag or
product identification markings have been altered or removed, or any product of any other
manufacturer.
Safety, Reliability and Performance
Mindray is not responsible for the effects on safety, reliability and performance of the
BC-3000plus Hematology Analyzer if:
■ assembly operations, extensions, re-adjusts, modifications or repairs are carried out
by persons other than those authorized by Mindray.
■ Personnel unauthorized by Mindray repairs or modifies the instrument.
Auto Hematology Analyzer Service Manual (V1.1) iii
Return Policy
Return Procedure
In the event that it becomes necessary to return a unit to Mindray, the following procedure
should be followed:
1. Obtain return authorization. Contact the Mindray Service Department and obtain a
Customer Service Authorization (Mindray) number . The Mindray number must appear
on the outside of the shipping container. Return shipments will not be accepted if the
Mindray number is not clearly visible. Please provide the model number, serial
number, and a brief description of the reason for return.
2. Freight policy. The customer is responsible for freight charges when equipment is
shipped to Mindray for service (this includes customs charges).
Name: Shanghai International Holding Corp. GmbH (Europe)
Address: Eiffestrasse 80 D-20537 Hamburg Germany
Phone: +49 40 2513175
Fax: +49 40 255726
iv Auto Hematology Analyzer Service Manual (V1.1)
Conventions Used in This Manual and Instrument
Warnings, Cautions and Notes
Warnings, cautions and notes are used in this manual to alert or signal the reader to
specific information.
WARNING
Warning alerts the user to the possible injury or death associated with the use or
misuse of the instrument.
CAUTION
Caution alerts the user to possible injury or problems with the instrument
associated with its use or problem such as instrument malfunction, instrument
failure, damage to the instrument.
NOTE
Note provides specific information, in the form of recommendations,
pre-requirements, alternative goods or supplemental information.
11.2 Upgrade System Software.................................................................................... 11-2
Appendix………………………………………………………………………………………..A-1
Hardware Diagram of BC-3000PLUS.............................................................................A-1
Hydraulic Diagram of BC-3000PLUS .............................................................................A-2
Auto Hematology Analyzer Service Manual (V1.1) 3
General
Chapter 1 General
1.1 Introduction
CAUTION
To maintain the instrument in normal condition, the user must perform the periodic
maintenance. Refer to the user manual.
This service manual provides useful information to help service personnel to understand,
troubleshoot, service, maintain and repair the Hematology Analyzer.
All replaceable parts or units of this instrument and its optional units are clearly list with
exploded illustration to help you locate the parts quickly.
The maintenance must be periodically performed because the instrument has fluid paths
and precision parts. Accordingly, the user is responsible for performing the periodic
maintenance. The “maintenance” chapter in this service manual describes the
maintenance that should be performed by the qualified service personnel. The
“maintenance” chapter in the user manual describes the maintenance that can be
performed by the user.
NOTE
If the instrument has a problem and there has been no periodic maintenance, the
instrument will usually be normal again by cleaning the fluid paths or replacing a
consumable with a new one.
The information in the user manual is primarily for the user. However, it is important for
service personnel to thoroughly read the user manual and service manual before starting
to troubleshoot, service, maintain or repair this instrument. This is because service
personnel needs to understand the operation of the instrument in order to effectively use
the instrument in order to effectively use the information in the service manual.
Auto Hematology Analyzer Service Manual (V1.1) 1-1
General
1.2 Service Policy
CAUTION
Be careful not to directly touch any place where blood is or may spread to.
Wear rubber gloves to protect yourself from infection before doing maintenance.
Our company’s basic policy for technical service is to replace faulty units, printed circuit
boards or parts. We do not support component-level repair of boards and units outside the
factory.
NOTE
When ordering parts or accessories from your nearest distributor, please quote the
part number and part name which is listed in the service manual, and the name or
model of the unit in which the required part is located. This will help us to promptly
attend to your needs.
Always use parts and accessories recommended or supplied by our company to
assure maximum performance from your instrument.
1-2 Auto Hematology Analyzer Service Manual (V1.1)
1.3 Specification
Hemoglobin Analysis
Wavelength 525nm
Sampling Features
Volumes Required for Each Analysis:
Whole Blood Mode (vein blood) 13uL
Prediluted Mode (capillary blood) 20uL
Aspirated volumes:
500uL of lyse first dilution per cycle for WBC measurement
300uL of second dilution per cycle for RBC and PLT measurement
Dilution Ratios Whole Blood Prediluted
General
WBC/HGB 1: 308 1:407
RBC/PLT 1:44833 1: 44274
Cell Counting Aperture Size:
WBC 100um
RBC 70um
Throughput more than 60 samples/hour
Check Diluent, Rinse and Lyse
The applied volume of each reagent is:
Diluent Rinse Lyse E-Z
Normal Startup 42ml 10ml
Prepare a sample
25.4ml 6ml 0.5ml
(whole blood)
Prepare a sample
25.1ml 6ml 0.26ml
(prediluted)
Normal Shutdown 32ml 10ml 1.6ml
Performance Specifications
Imprecision
Imprecision is based on replicate determinations of the same sample. The first
Auto Hematology Analyzer Service Manual (V1.1) 1-3
General
result is not used in the calculation.
Imprecision Specifications
Parameter Level Units CV%
WBC 7.0-15.0 109/L
RBC 3.5-6.0 1012/L
HGB 110 – 180 g/L
MCV 80.0 – 110.0 fL
PLT 200 – 500 109/L
Operating Range
Parameter Range Units
WBC 0.0-999.9 109/L
RBC 0.00-9.99 1012/L
HGB 0-300 g/L
MCV 0-250 fL
PLT 0-3000 109/L
≤ 2.5
≤ 2
≤ 1.5
≤ 0.5
≤ 5
Linearity
Parameter Linearity Range Units
WBC 0.3-99.9 109/L ±0.3 or ±5%
RBC 0.20-9.99 1012/L ±0.05 or ±5%
HGB 0-300 g/L ±2 or ±3%
50/60±1 Hz 50/60±1 Hz
Consumption: 180 VA 180 VA
Fuse: 2A 4A
Ambient Temperature and Humidity
Temperature:
15℃~35℃ (59℉~95℉)
Humidity:
10%~85% without condensation
Dimensions
Height Width Depth
46cm 39cm 40cm
Weight
25KG
Recommended Anticoagulant
A salt of K
EDTA with the proper proportion of blood to anticoagulant, as specified by
2
the tube manufacturer.
Sample Identification
An 8-digit identification number is mandatory sample identification.
Auto Hematology Analyzer Service Manual (V1.1) 1-5
General
Results Output
The system can transmit sample and control data to an external computer.
Sample results screen shows sample identification number, sample mode, sample
results and any sample result flags.
The system provides a printout of all data.
1-6 Auto Hematology Analyzer Service Manual (V1.1)
1.4 Panel Description
1.4.1 Front Panel and Keys
Figure 1-1
No. Name Description
General
1 Display Screen Display various messages, measured data and histograms
2 Keypad Touch key (all of the description refer to under lists), 23 buttons
3 Recorder Print out measured result
4 Power Light Show hematology analyzer work status
5 [Start] key Press to aspirate the sample and start counting
6 Sample Probe Aspirate the sample
Dispenses the diluent when in capillary blood mode.
Keypad
1
[START]
In Count screen, QC Count screen and Auto Calibration screen,
press it to count. In the status of Adding Diluent, press it to add
Diluent.
2
[MENU]
Press this key to switch between window operation and menu
operation
3
4
[PRINT]
[FEED]
Press this key to print using either recorder or printer
Press this key to feed paper of the recorder. Release it to stop the
operation.
5
6
[MUTE]
[DEL]
Mute the alarm and clear some of the error messages.
Delete the selected data in Review screen. Delete error message
in Error Message screen. Delete reference data and running
control data in QC Edit screen. Call default value in Normal
Range screen.
7
[0]...[9]
Auto Hematology Analyzer Service Manual (V1.1) 1-7
Enter numbers
General
8
9
10
11
12
13
14
[↑][↓][←][→]
[ID]
[DILUENT]
[PgUp][PgDn]
[ENTER]
[STARTUP]
[FLUSH]
Move the cursor in the window area or menu area.
Enter the ID number of the sample
In the Count screen of Prediluted mode, press this key to enter
the Adding Diluent status.
Scroll the screen up or down page by page.
Confirm
Clean the tubing, baths and sample probe then check the
background.
Press the key to execute the Flush operation to remove the clogs
1-8 Auto Hematology Analyzer Service Manual (V1.1)
1.4.2 Rear Panel
General
1
2
3
4
5
6
1
1
1
0
9
8
7
Figure 1-2
No. Name Description
1 Keyboard Interface Connect the standard keyboard
2 RS-232C Serial Port 1 Connect computer and transfer data to computer
CAUTION
In order to avoid any safety hazard, only coonect personal
computer which are approved to IEC950
The instrument should only be connected to an external
instrument which complies with the CISPR 11 Second
Edition 1990-09, Group 1 and Class B standard
3 RS-232C Serial Port 2 Connect a bar code scanner
4 Printer Interface Connect the external print er LX-300+ (LX-300)
5 DILUENT Tubing Connector Inlet for diluent. Connect one end of the tube (standard
accessory) to the diluent inlet and attach the other end of the
tube to the diluent
6 BNC socket for DILUENT
sensor
7 BNC socket for RINSE
sensor
Auto Hematology Analyzer Service Manual (V1.1) 1-9
connector for diluent. Connect one end of the connector of the
cable.
connector for rinse. Connect one end of the connector of the
cable.
General
8 WASTE Tubing Connector Inlet for waste. Connect one end of the tube (standard
accessory) to the waste inlet and attach the other end of the
tube to the waste
9 RINSE Tubing Connector Inlet for rinse. Connect one end of the tube (standard
accessory) to the rinse inlet and attach the other end of the
tube to the rinse
10 Equipotential ground
terminal
11 Power switch
AC source
Fuse holder
Connects the ground lead to the Equipotential ground terminal
on the wall for earth grounding
Turns power on or off
Connects the AC power cord to supply the AC power to the
instrument
Contains the time lag fuse (T 2A for 220V or T 4A for 110v)
Fuses cut the power off when an abnormality occurs in the
hematology analyzer. Remove the malfunction before
replacing the fuse.
Before replacing a fuse, turn the power off anf disconnect
the AC power cord from the instrument.
Fuse replacement should be done by a qualified person.
CAUTION
1-10 Auto Hematology Analyzer Service Manual (V1.1)
1.4.3 Front review without front panel
General
1
2
3
4
5
9
Figure 1-3
1--- Fluctuating Motor
2--- Sample Probe
3--- Sample Probe Wipe Block
4--- WBC unit shield
5--- RBC/PLT unit shield
6--- [Start] key
7---Valve 11
8--- Valve 12
9---Floppy Disk Driver
6
8
7
Auto Hematology Analyzer Service Manual (V1.1) 1-11
1-12 Auto Hematology Analyzer Service Manual (V1.1)
1.4.5 Left-side view without the door
General
Figure 1-5
1---hard disk (Module on disk)
2---vacuum pump
3---pressure pump
4---pressure chamber
Auto Hematology Analyzer Service Manual (V1.1) 1-13
General
1.5 Menu Structure Chart
Count
Whole Blood
Sample Mode
Review
Prediluted
Sample Review
Search Review
Sample Table R eview
Sample Histogram Review
Search Table Review
Search Histogram Review
Qu a lity Control
Setup
Com merical
Control
X-B Analysis
Print
Count Time
Password
Patie n t L imits
Transm ission
Date & Time
Gain
Auto Clean Time
Re ag e n t E x p. Date
Prin t C a ptio n
Parameter U n its
QC Edit
QC Count
QC Graph
QC Table
Limit
Sample /B atc h
Start/Stop
X-B Graph
X-B Table
General
Man
Woman
Ch ild
Neonate
File 1
File 1
File 2
File 3
File 4
File 5
File 6
File 7
File 8
File 2
File 3
File 4
File 5
File 6
File 7
File 8
File 9
File 9
WBC Count Time
RBC Count Time
Mid Max Width
File 1
File 2
File 3
File 4
File 5
File 6
File 7
File 8
File 9
Prin t
Select
Prin t
Format
Auto
Print
Version
Language
Type
File 1
File 2
File 3
File 4
File 5
File 6
File 7
File 8
File 9
Service
M ain te na n ce
System Status
Valve Test
Prepare to Ship
Error Messa ge
Ca libr atio n
Help
M an u a l C a lib ra ton
Au to C a lib rat ion
Shutdown
:item s ca n be v ie w e d O n ly af ter in pu t th e co rr es po n d in g pa s sword
:included items, not sub-menu
1-14 Auto Hematology Analyzer Service Manual (V1.1)
Pale tte
Recorder
Type
Chapter 2 Troubleshooting
r
A
2.1 Check Procedure
Check the instrument according to the check procedure below.
Measurement operation check
Was the quantity of each reagent sufficient fo
measurement?
Were the correct or recommended reagents used?
Was the operating temperature proper?
Was the supplied main power voltage correct?
fter turning on the instrument.
Did the instrument fail to generate an alarm?
NO DILUENT
HARDWARE FAIL
Background noise measurement.
Did the instrument fail to generate an alarm?
Was the result within the specification?
Control measurement
Did the instrument fail to generate an alarm?
Was the result reproducibility good for:
HGB? RBC?
WBC? PLT?
HCT?
(Was the obtained data within the range?)
END
before Instrument Check”
Troubleshooting
Refer to “Check Items
Refer to
“Troubleshooting
and Alarm”
Auto Hematology Analyzer Service Manual (V1.1) 2-1
Troubleshooting
2.2 Check Items before Instrument Check
Use the instrument and diluent under the following
Check items before
Instrument check
operating conditions:
Around instrument Diluent
- temperature: 15 to 35℃ temperature: 15 to 30℃
- humidity: 10 to 85%
- atmospheric pressure: 860 to 1060hPa (Working)
If the temperature is less than 15℃, it slows the
reaction rate from hemoglobin to cyanmethemoglobin.
This may result in increase of the hemoglobin data. It
may also result in increase of the WBC count because
the RBCs are not sufficiently hemolysed due to the
lower temperature. Insufficiently hemolyzed RBCs will
be included in the WBC count as RBC ghosts.
Sampled Whole Blood
Handling Check
Storage for Blood Sample
Measure all required parameters soon after sampling
the whole blood from a patient. As time elapses after
blood sampling, the blood cells’ volume and density
change. The ratios of the volume and density
variations depend on the environmental conditions and
patient. If the blood sample isleft in an air conditioned
room for a long time, the volume of the red blood cell
increases and the MCV, RDW and MPV will be
affected, and moreover, the PLT will be easily
aggregated.
WBC part differential
To get high reliability on the acquired data, measure
the blood samples within 6 hours after sampling the
whole blood. If the blood sample is left in an air
conditioned room for a long time, geerally, the WBC
membrane’s resistance against hemolysing reagent is
decreased. Therefore the WBC histogram of the
correct shape cannot be obtained.
Blood Sample from a Patient with Specified Conditions
To measure a blood from a patient who has
hepatopathy, certain special treatments, or is a
neonate, it may be necessary to use a method other
than the hematology. Analyzer. This is because the
RBC membrane’s resistance against hemolysing
2-2 Auto Hematology Analyzer Service Manual (V1.1)
Capillary Blood Handing
Check
Troubleshooting
reagent is increased (insufficient hemolysing) and it
will cause an increase of the WBC count when the
blood is measured with the hematology analyzer.
Furthermore, the bilirubin and WBC in the blood may
affect the hemoglobin concentration in the
measurement.
CAUTION
In the capillary blood mode, the instrument
aspirates the diluted sample of 20uL. In this mode,
if the venous blood is incorrectly aspirated instead
of capillary blood, there is a high possibility that
the fluid path is clogged or the background noise
is not easily decreased.
Most causes of data error using capillary blood are due
to incorrect technique for the capillary blood sampling
and diluting. Therefore, take care the following notes
and make a capillary blood sample.
NOTE
Dilute the sampled capillary blood correctly the
first time, because it is difficult to sample the
blood twice from the capillary.
Auto Hematology Analyzer Service Manual (V1.1) 2-3
Troubleshooting
2.3 How to Check Sample Data
Background Noise Check
This check is used to make sure that the counted and
calculated data of a diluent sample is not affected by
background noise. If the background checking value
exceeds the tolerable dilute data shown in the table
below, the diluent data counted and calculated before
background noise is reduced erroneous. In the table
below, each diluent data is defined as follows:
Recommended diluent data
This data is best for acquiring accurate data of the
sample.
Acceptable dilunt data
This data is the minimum value for acquiring accurate
data of the sample.
Refer to “Troubleshooting Erroneous Data” of this
chapter for the possible causes of background noise
and how to reduce it.
Check Procedure
1. Press the start key to count and calculate the
2. Make sure the counted and calculated data is less
Parameter Data Check with Diluent
Check that the background values are less than or
equal to the data in the previous table. Discard the
other parameter values because they are not affected
by noise.
Especially check the data for the PLT parameters.
When the diluent includes the particles of dust smaller
9/L
10
0.3x
12/L
10
0.03x
9/L
10
10x
diluent. There is no need to aspirate the diluent
from the sampling probe.
than or equal to the acceptable diluent data as
shown upper. If they are out of range, decrease the
background noise.
2-4 Auto Hematology Analyzer Service Manual (V1.1)
Loading...
+ 169 hidden pages
You need points to download manuals.
1 point = 1 manual.
You can buy points or you can get point for every manual you upload.