Page 1
LyovaporTM L-200 / L-200 Pro
Operation Manual
11593861D en
Page 2
Imprint
Product Identification:
Operation Manual (Original) LyovaporTM L-200 / L-200 Pro
11593861
Publication date: 09.2017
BÜCHI Labortechnik AG
Meierseggstrasse 40
Postfach
CH-9230 Flawil 1
E-Mail: quality@buchi.com
BUCHI reserves the right to make changes to the manual as deemed necessary in the light of experience, especially with respect to structure, illustrations and technical details.
This manual is copyrighted. Information from it may neither be reproduced, distributed, or used for competitive purposes, nor made available to third parties. The manufacture of any component with the aid of
this manual without prior written agreement is also prohibited.
Page 3
BÜCHI Labortechnik AG Contents
Contents
1 About this document........................................................................................................... 7
1.1 Connected devices .............................................................................................................................. 7
1.2 Warning notices in this document........................................................................................................ 7
1.3 Symbols............................................................................................................................................... 7
1.3.1 .................................................................................................................................................7
1.3.2 Mandatory directive symbols ...................................................................................................7
1.3.3 Mark-ups and symbols.............................................................................................................8
1.4 Available languages............................................................................................................................. 8
1.5 Trademarks.......................................................................................................................................... 8
2 Safety....................................................................................................................................9
2.1 Proper use ........................................................................................................................................... 9
2.2 Use other than that intended ............................................................................................................... 9
2.3 Staff qualification ................................................................................................................................. 9
2.4 Location of warning signs on the product .......................................................................................... 10
2.5 Residual risks .................................................................................................................................... 10
2.5.1 Faults during operation .......................................................................................................... 10
2.5.2 Damage to the ice condenser................................................................................................10
2.5.3 Glass and acrylic breakage.................................................................................................... 10
2.5.4 Low internal pressure.............................................................................................................11
2.5.5 Cold and hot surfaces............................................................................................................11
2.6 Personal protective equipment .......................................................................................................... 11
2.7 Modifications...................................................................................................................................... 11
3 Product description........................................................................................................... 12
3.1 Description of function ....................................................................................................................... 12
3.1.1 Freezing phase ...................................................................................................................... 12
3.1.2 Main drying phase..................................................................................................................12
3.1.3 Secondary-drying phase........................................................................................................13
3.2 Configuration ..................................................................................................................................... 14
3.2.1 Front view ..............................................................................................................................14
3.2.2 Rear view ...............................................................................................................................14
3.2.3 Connections on the rear side.................................................................................................15
3.2.4 Control panel..........................................................................................................................15
3.2.5 Pro control panel....................................................................................................................16
3.3 Type plate.......................................................................................................................................... 16
3.4 Refrigerant Specification.................................................................................................................... 16
3.5 Specifications supplied ...................................................................................................................... 17
3.6 Technical Data................................................................................................................................... 17
3.6.1 Lyovapor™ L-200 ..................................................................................................................18
3.6.2 Ambient conditions.................................................................................................................18
3.6.3 Materials ................................................................................................................................18
4 Transport and storage ......................................................................................................19
4.1 Transport ........................................................................................................................................... 19
4.2 Storage .............................................................................................................................................. 19
4.3 Lifting the instrument ......................................................................................................................... 19
Operation Manual LyovaporTM L-200 / L-200 Pro iii
Page 4
Contents BÜCHI Labortechnik AG
5 Installation.......................................................................................................................... 21
5.1 Installation site................................................................................................................................... 21
5.2 Securing against earthquakes ........................................................................................................... 21
5.3 Putting the instrument in operation.................................................................................................... 22
5.3.1 Preparing the instrument........................................................................................................22
5.3.2 Establishing electrical connections ........................................................................................ 22
5.3.3 Assembling the cross fitting (optional accessory)..................................................................24
5.3.4 Assembling the main valve (optional accessory)...................................................................25
5.3.5 Assembling pressure sensor PPG010 (optional accessory)..................................................27
5.3.6 Assembling the venting valve (optional accessory) ............................................................... 28
5.3.7 Assembling the pressure regulating valve (optional accessory)............................................29
5.3.8 Assembling the alternative pressure sensor (optional accessory).........................................30
5.3.9 Preparing the condensate drain hose....................................................................................31
5.4 Commissioning the vacuum pump..................................................................................................... 32
5.5 Assembling the drying attachments................................................................................................... 32
5.5.1 Fitting the 300 mm dia. O-ring ...............................................................................................32
5.5.2 Fitting the acrylic drying chamber .......................................................................................... 33
5.5.3 Fitting the manifold acrylic drying chamber............................................................................ 34
5.5.4 Fitting the stopper acrylic drying chamber ............................................................................. 35
5.5.5 Assembling the manifold drying rack ..................................................................................... 36
5.5.6 Fitting the non-heatable shelf.................................................................................................37
5.5.7 Fitting heatable shelves ......................................................................................................... 39
5.5.8 Assembling manifold valves................................................................................................... 42
6 Operating the control panel.............................................................................................. 45
6.1 Layout of the control panel ................................................................................................................ 45
6.2 Function bar....................................................................................................................................... 45
6.3 Menu bar............................................................................................................................................ 46
6.3.1 Start menu .............................................................................................................................47
6.3.2 Favourites menu .................................................................................................................... 47
6.3.3 Configuration menu................................................................................................................47
6.3.4 Messages menu.....................................................................................................................50
6.4 Status bar .......................................................................................................................................... 50
6.5 Carrying out freeze-drying ................................................................................................................. 52
6.5.1 Preparing the instrument........................................................................................................52
6.5.2 Starting freeze-drying.............................................................................................................52
6.5.3 Editing parameters while the process is running ...................................................................52
6.5.4 Ending freeze-drying..............................................................................................................53
6.5.5 Shutting down the instrument ................................................................................................53
iv Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 5
BÜCHI Labortechnik AG Contents
7 Operating Pro control panel .............................................................................................54
7.1 Layout of Pro control panel................................................................................................................ 54
7.2 Function bar....................................................................................................................................... 54
7.3 Menu bar............................................................................................................................................ 56
7.3.1 Start menu .............................................................................................................................56
7.3.2 Favourites menu .................................................................................................................... 56
7.3.3 Method menu.........................................................................................................................57
7.3.4 Configuration menu................................................................................................................57
7.3.5 Messages menu.....................................................................................................................60
7.4 Status bar .......................................................................................................................................... 60
7.5 Editing a method................................................................................................................................ 62
7.5.1 Creating a new method..........................................................................................................62
7.5.2 Changing the name of a method............................................................................................62
7.5.3 Setting the sample collapse temperature............................................................................... 62
7.5.4 Setting the gas type ............................................................................................................... 63
7.5.5 Setting the shelf loading temperature .................................................................................... 63
7.5.6 Setting the steps of a method ................................................................................................ 63
7.5.7 Setting the phases of a method ............................................................................................. 65
7.6 Deleting a method.............................................................................................................................. 67
7.7 Setting end point definitions............................................................................................................... 67
7.7.1 Pressure difference test.........................................................................................................67
7.7.2 Temperature difference test...................................................................................................68
7.8 Performing freeze-drying using a method [Pro control panel] ........................................................... 69
7.8.1 Preparing the instrument........................................................................................................69
7.8.2 Selecting a method ................................................................................................................ 69
7.8.3 Starting freeze-drying.............................................................................................................70
7.8.4 Ending freeze-drying..............................................................................................................71
7.8.5 Shutting down the instrument ................................................................................................71
7.9 Performing freeze-drying manually [Pro control panel]...................................................................... 71
7.9.1 Preparing the instrument........................................................................................................71
7.9.2 Starting freeze-drying.............................................................................................................72
7.9.3 Editing parameters while the process is running ...................................................................72
7.9.4 Ending freeze-drying..............................................................................................................73
7.9.5 Shutting down the instrument ................................................................................................73
8 Mobile connection .............................................................................................................74
8.1 Setting up BUCHI Connect Solution.................................................................................................. 74
8.2 Handling data..................................................................................................................................... 75
8.3 Connecting the instrument to the LAN............................................................................................... 75
8.4 Requirements for local network settings............................................................................................ 75
8.5 Assigning a dynamic IP address........................................................................................................ 76
8.6 Enabling the control panel on the BUCHI Cloud................................................................................ 76
8.7 Downloading the BUCHI Monitor app................................................................................................ 76
8.8 Layout of BUCHI Monitor app............................................................................................................ 77
8.9 Connecting the instrument and app using a QR code....................................................................... 77
8.9.1 Generating a QR code...........................................................................................................77
8.9.2 Scanning the QR code...........................................................................................................78
8.10 Connecting the instrument and app using a password...................................................................... 79
8.10.1 Generating a password..........................................................................................................79
8.10.2 Entering the password ........................................................................................................... 79
8.11 Removing the instrument from the app.............................................................................................. 80
8.12 Enabling notifications......................................................................................................................... 80
8.13 Remotely retrieving process data ...................................................................................................... 81
Operation Manual LyovaporTM L-200 / L-200 Pro v
Page 6
Contents BÜCHI Labortechnik AG
9 Cleaning and servicing .....................................................................................................82
9.1 Regular maintenance work................................................................................................................ 82
9.2 Performing a leak test........................................................................................................................ 84
9.3 Performing a vacuum test.................................................................................................................. 84
10 Help with faults ..................................................................................................................86
10.1 Troubleshooting................................................................................................................................. 86
10.2 Faults, possible causes and remedies............................................................................................... 86
11 Taking out of service and disposal.................................................................................. 88
11.1 Disposal............................................................................................................................................. 88
11.2 Returning the instrument ................................................................................................................... 88
12 Appendix ............................................................................................................................89
12.1 Spare parts and accessories ............................................................................................................. 89
12.1.1 Top-mount drying rack accessories .......................................................................................89
12.1.2 Accessories............................................................................................................................91
12.1.3 Further accessories ...............................................................................................................92
12.1.4 Spare parts ............................................................................................................................93
vi Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 7
BÜCHI Labortechnik AG About this document | 1
1 About this document
These operating instructions describe the Lyovapor™ L-200 at the time supplied.
They are an integral part of the product and contain important information that is necessary for safe operation and maintenance.
These operating instructions apply to all variants of the Lyovapor™ L-200.
u To ensure safe and trouble-free operation, read these operating instructions be-
fore starting up the device and follow the guidance they contain.
u Keep the operating instructions somewhere near to the device.
u Pass on the operating instructions to any subsequent owner or user.
BÜCHI Labortechnik AG accepts no liability whatsoever for any faults or damages
that result from the failure to follow these operating instructions.
u If you still have any questions after reading these operating instructions, please
contact BÜCHI Labortechnik AG Customer Service. Contact details for your local
agents can be found on the back cover of these operating instructions or on the Internet at http://www.buchi.com.
1.1 Connected devices
In addition to these operating instructions, you should also follow the instructions and
specifications in the documentation for the connected devices.
1.2 Warning notices in this document
Warning notices warn you of dangers that can occur when handling the device. There
are four danger levels, each identifiable by the signal word used.
Signal word Meaning
DANGER Indicates a danger with a high level of risk which could result in
death or serious injury if not prevented.
WARNING Indicates a danger with a medium level of risk which could result in
death or serious injury if not prevented.
CAUTION Indicates a danger with a low level of risk which could result in mi-
nor or medium-severity injury if not prevented.
IMPORTANT Indicates a danger that could result in damage to property.
1.3 Symbols
The following symbols may be displayed in this instruction manual or on the device:
1.3.1
1.3.2 Mandatory directive symbols
Symbol Meaning Symbol Meaning
Wear safety goggles Wear protective clothing
Wear protective gloves Heavy load, do not lift with-
Operation Manual LyovaporTM L-200 / L-200 Pro
out assistance
7/96
Page 8
1 | About this document BÜCHI Labortechnik AG
1.3.3 Mark-ups and symbols
NOTE
This symbol draws attention to useful and important information.
R This character draws attention to a requirement that must be met before the in-
structions below are carried out.
u This character indicates an instruction that must be carried out by the user.
5 This character indicates the result of a correctly carried out instruction.
Mark-up Explanation
Window Software Windows are marked-up like this.
Tab Tabs are marked-up like this.
Dialog Dialogs are marked-up like this.
Button Buttons are marked-up like this.
Field n am es Field names are marked-up like this.
Menu / Me nu item Menus or menu items are marked-up like this.
Status Status is marked-up like this.
Signal Signals are marked-up like this.
1.4 Available languages
These operating instructions were originally produced in German and have been
translated into several other languages. The translations are available on the enclosed CD or can be obtained as a PDF file via http://www.buchi.com.
1.5 Trademarks
Product names and registered or unregistered trademarks that are used in this instruction manual are used only for identification and remain the property of the owner
in each case.
8/96
Operation Manual LyovaporTM L-200 / L-200 Pro
Page 9
BÜCHI Labortechnik AG Safety | 2
2 Safety
2.1 Proper use
The Lyovapor™ L-200 is used for freeze-drying solid materials in ampoules, vials,
dishes, round-neck or wide-neck flasks and is exclusively intended for that purpose.
The Lyovapor™ L-200 can be used in laboratories for the following tasks:
Sublimating and condensing water
2.2 Use other than that intended
Use of any kind other than that described in the section Chapter2.1 "Proper use",
page9 and any application that does not comply with the technical specifications
(see Technical data) constitutes use other than that intended.
In particular, the following applications are not permissible:
Use of the instrument in an environment with a potential risk of explosion or areas
which require explosion-safe apparatus.
Use of the instrument for processing substances outside of research and develop-
ment.
Production and processing of substances that can lead to spontaneous reactions,
such as explosives, metal hydrides or solvents that can form peroxides.
Processing with explosive gas mixtures.
Damage or hazards attributable to use of the product other than as intended are entirely at the risk of the operator alone.
2.3 Staff qualification
Unqualified persons are unable to identify risks and are therefore exposed to greater
dangers.
The device may only be operated by suitably qualified laboratory staff.
These operating instructions are aimed at the following target groups:
Users
Users are persons that meet the following criteria:
They have been instructed in the use of the device.
They are familiar with the contents of these operating instructions and the applica-
ble safety regulations and apply them.
They are able on the basis of their training or professional experience to assess
the risks associated with the use of the device.
Operator
The operator (generally the laboratory manager) is responsible for the following aspects:
The device must be correctly installed, commissioned, operated and serviced.
Only suitably qualified staff may be assigned the task of performing the operations
described in these operating instructions.
The staff must comply with the local applicable requirements and regulations for
safe and hazard-conscious working practices.
Safety-related incidents that occur while using the device should be reported to the
manufacturer (quality@buchi.com).
Operation Manual LyovaporTM L-200 / L-200 Pro
9/96
Page 10
2 | Safety BÜCHI Labortechnik AG
BUCHI service technicians
Service technicians authorized by BUCHI have attended special training courses and
are authorized by BÜCHI Labortechnik AG to carry out special servicing and repair
measures.
2.4 Location of warning signs on the product
The following warning symbols are present on the instrument.
Fig.1: Location of warning signs on the product
General warning
2.5 Residual risks
The device has been developed and manufactured using the latest technological advances. Nevertheless, risks to persons, property or the environment can arise if the
device is used incorrectly.
Appropriate warnings in this manual serve to alert the user to these residual dangers.
2.5.1 Faults during operation
If a device is damaged, sharp edges or exposed electrical wires can cause injuries.
u Regularly check device for visible damage.
u If faults occur, switch off the device immediately, unplug the power cord and in-
form the operator.
u Do not continue to use devices that are damaged.
2.5.2 Damage to the ice condenser
Damage to the ice condenser leads to coolant leakage and failure of the instrument.
u Wait until the ice is completely thawed.
u Do not use mechanical means to remove ice from the ice condenser.
2.5.3 Glass and acrylic breakage
Broken glass and acrylic can cause severe cuts.
Damaged glass and acrylic components may implode if subjected to a vacuum.
Minor damage to the ground joints impairs the sealing effect and may therefore diminish sublimination capacity.
10/96
Operation Manual LyovaporTM L-200 / L-200 Pro
Page 11
BÜCHI Labortechnik AG Safety | 2
u Handle the flask and other glass and acrylic components carefully and do not drop
them.
u Always place the flasks in a suitable holder when they are not mounted on the Ly-
ovapor™.
u Always visually inspect glass and acrylic components for damage every time they
are to be used.
u Do not continue to use glass and acrylic components that are damaged.
u Always wear protective gloves when disposing of broken glass and acrylic.
2.5.4 Low internal pressure
Evacuating the system reduces the pressure in the drying chamber. This reduced
pressure can cause glass and acrylic components to implode.
u Make sure that all glass and acrylic components are free of damage.
2.5.5 Cold and hot surfaces
The condenser coil and probes can be extremely cold. Heatable shelf areas can be
extremely hot. If touched, hot and cold surfaces can cause skin burns.
u Do not touch cold or hot surfaces or liquids and/or wear suitable protective gloves.
2.6 Personal protective equipment
Depending on the application, hazards due to heat and/or corrosive chemicals may
arise.
u Always wear appropriate personal protective equipment such as safety goggles,
protective clothing and gloves.
u Make sure that the personal protective equipment meets the requirements of the
safety data sheets for all chemicals used.
2.7 Modifications
Unauthorized modifications may impair safety and lead to accidents.
u Use only genuine BUCHI accessories, spare parts and consumables.
u Technical modifications to the device or accessories should only be carried out
with the prior written approval of BÜCHI Labortechnik AG and only by authorized
BUCHI technicians.
BUCHI accepts no liability whatsoever for damage arising as a result of unauthorized
modifications.
Operation Manual LyovaporTM L-200 / L-200 Pro
11/96
Page 12
3 | Product description BÜCHI Labortechnik AG
3 Product description
3.1 Description of function
The Lyovapor™ is a freeze-dryer in which frozen preparations can be gently dried.
The basis of freeze-drying is sublimation. Sublimation refers to the process whereby a
substance transforms directly from the solid to the gaseous state.
The physical process of sublimation can be explained using the solvent water as an
example.
The water is frozen.
The frozen water is transformed into the gaseous state under vacuum at a pres-
sure below the triple point.
The vacuum prevents the ice melting when heat is applied to the preparation.
Thus, freeze-drying takes place in three phases:
1. Freezing phase: the preparation is frozen at atmospheric pressure.
2. Main drying phase: heat is applied to the frozen preparation under a vacuum.
The frozen water is removed by sublimation.
3. Secondary drying phase (only possible with heatable shelves): the trace levels of water remaining are removed by heating.
The Lyovapor™ consists of an ice condenser and various top-mount drying racks.
The top-mount drying racks can be chosen to suit the availability of the preparation
being dried and the requirements of the end product.
The following top-mount drying racks can be used:
Non-heatable and heatable shelves in rack
Trays in rack
Top-mount rack with manifold valves
3.1.1 Freezing phase
In the freezing phase, the aqueous preparation is transformed to a solid state. Freezing takes place under atmospheric pressure using a separate freezer, a liquid nitrogen bath, or a mixture of dry ice and alcohol.
The end of the freezing phase is reached as soon as the water contained in the
preparation has fully crystallized.
3.1.2 Main drying phase
In the main drying phase, the ice crystals are removed from the preparation by sublimation. Sublimation in the Lyovapor™ takes place under a vacuum with the addition
of thermal energy.
To create the vaccum, the pressure is lowered to the level required for sublimation.
For water that is: less than 6.11mbar.
As the ice condenser is colder than the preparation being dried, the vapour pressure
in the area of the ice condenser is lower than in the area of the preparation. The water vapour escaping from the preparation therefore flows towards the ice condenser.
The water vapour condenses on the coil of the ice condenser.
If a manifold-valve rack is used, heat transfer takes place by convection and radiation
from the surroundings. Control of the thermal energy transferred is then difficult.
12/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 13
BÜCHI Labortechnik AG Product description | 3
If using a drying chamber with heatable shelves, heat transfer takes place by direct
contact. The temperature of the heatable shelves is controllable. Control of the thermal energy transferred is then possible.
Controlling the heat transfer prevents the following critical temperatures for amorphous and crystalline materials to be reached:
the glass transition temperature Tg' of the frozen preparation
the collapse temperature Tc.
the eutectic temperature Teu.
Above the glass transition temperature and the collapse temperature, the viscosity of
the frozen preparation increases. The increased viscosity leads to the collapse of the
preparation's matrix structure.
Above the eutectic temperature, the preparation melts.
During the main drying phase, the product temperature must remain below the collapse temperature for amorphous materials in the preparation.
Sublimation of the ice crystals progresses downwards from the surface of the product.
Above the sublimation boundary, the product is dry ("freeze-dried cake"), while further
inside the product is still frozen.
The end of the main drying phase is reached when all ice crystals have been removed from the preparation.
After the main drying phase, the remaining fluid content in the preparation can still be
between 5 to 10%.
3.1.3 Secondary-drying phase
In the secondary-drying phase, the unfrozen water is removed from the preparation
by desorption. The secondary-drying function is performed by the heatable shelves in
the drying chamber of the Lyovapor™.
In the secondary-drying phase, the temperature of the heatable shelves is raised and
held for several hours.
The end of the secondary-drying phase is reached when the residual moisture in the
preparation is between 1% and 5%.
Operation Manual LyovaporTM L-200 / L-200 Pro 13/96
Page 14
3 | Product description BÜCHI Labortechnik AG
3
5
2
1
4
3
2
1
3.2 Configuration
3.2.1 Front view
Fig.2: Front view Lyovapor™ L-200
1 Connections for heatable shelves
2 Ice condenser
(Lyovapor™ L-200 Pro only)
3 Ventilation slots 4 On/Off master switch
5 Control panel
3.2.2 Rear view
Fig.3: Rear viewLyovaporTM L-200
1 Connections on the rear side
(See Chapter3.2.3 "Connections on
2 Drain hose for condensate
the rear side", page15)
3 Ventilation slots
14/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 15
BÜCHI Labortechnik AG Product description | 3
4
3
14
15
2
1
11
9
8
7
5
6
10
12
13
1
2
3
3.2.3 Connections on the rear side
Fig.4: Connections on the rear side
1 Vacuum pump connection 2 Vacuum connection
3 Type Plate 4 Refrigerant specification
5 Main valve connection 6 Control valve connection
7 Aeration valve connection 8 Spare
9 External pressure sensor connection 10 Internal pressure sensor connection
11 LAN port 12 COM port
13 Power supply connection 14 Fuse
15 Fuse
3.2.4 Control panel
Fig.5: Control panel
1 View 2 Function buttons
3 Navigation control
Operation Manual LyovaporTM L-200 / L-200 Pro 15/96
Page 16
3 | Product description BÜCHI Labortechnik AG
1
2
Buchi Operations India Private Limited
394230 Surat / India
Type xxx
SN xxxxxxxx
Volt xxx-xxx VAC
Freq xx Hz
Power xxxx W
Built 20xx
Designed by BUCHI in Switzerland
Made in India
6
5
4
1
3
2
7
8
9
10
9
3.2.5 Pro control panel
Fig.6: Pro control panel
1 Touch-screen display 2 Navigation control
3.3 Type plate
The type plate identifies the instrument. The type plate is located at the rear of the instrument.
Fig.7: Type Plate
1 Company name and address 2 Instrument name
16/96 Operation Manual Lyovapor
3.4 Refrigerant Specification
3 Serial number 4 Input voltage range
5 Frequency 6 Power consumption maximum
7 Year of manufacture 8 Product code
9 Approvals 10 Symbol for "Do not dispose of as
household waste"
The refrigerant details are at the back of the instrument.
TM
L-200 / L-200 Pro
Page 17
BÜCHI Labortechnik AG Product description | 3
L-xxx xxHz
Cooling System Refrigerant: Rxxx
Filling: xxx g
Global Warming Potential (GWP): xx tCO
2
High Side design pressure: xxx
Low Side design pressure: xxx
6
4
1
2
5
3
Fig.8: Refrigerant details
1 Instrument name 2 Refrigerant details
3 Filling capacity 4 Global warming potential
3.5 Specifications supplied
NOTE
The scope of delivery depends of the configuration of the purchase order.
Accessories are delivered as per the purchase order, order confirmation, and delivery note.
Component Specifications
supplied
Lyovapor™ L-200 or
Lyovapor™ L-200 Pro
Power cord 1
Operation Manual 1
Technical data sheet 1
Vacuum clamp, ISO-KF 16 1
Vacuum clamps, ISO-KF 25 2
Vacuum seal, ISO-KF 16 1
Vacuum seals, ISO-KF 25 2
O-ring 300mm 2
Vacuum tubing adaptor, ISO-KF 16 to ISO-KF 25 1
Cross-pipe (inc. seals and clamps)* 1
90° elbow, ISO-KF 16* 2
Main valve (inc. seals and clamps)* 1
Pressure-regulating valve (inc. seals and clamps)* 1
Pressure sensor PPG010 (inc. seals and clamps)* 1
Venting valve (inc. seals and clamps)* 1
1
* Option
3.6 Technical Data
Dimensions without drying attachments
Operation Manual LyovaporTM L-200 / L-200 Pro 17/96
(W x D x H)
Weight without drying attachments 75kg
460 x 585 x 510 mm
Page 18
3 | Product description BÜCHI Labortechnik AG
3.6.1 Lyovapor™ L-200
Specification L-200 for 50Hz L-200 for 60Hz
Dimensions without drying attach-
460×585×510mm 460×585×510mm
ments (W x D x H)
Weight 75kg 75kg
Connection voltage 220-240 VAC 208-230 VAC
Power consumption
1200 W 1200 W
(rated)
Power consumption
1800 W 1800 W
(maximum)
Lug 10 A/250 V 10 A/250 V
Frequency 50 Hz 60 Hz
Overvoltage category II II
Protection rating IP20 IP20
Pollution degree 2 2
3.6.2 Ambient conditions
The Lyovapor™ may only be used in indoor areas.
Max. altitude above sea level 2000 m
Ambient temperature 15 - 30 °C (25 °C)
Maximum relative humidity 80% for temperatures up to 30 °C
Storage temperature max. 45 °C
3.6.3 Materials
Component Material of construction
Lyovapor™ housing Steel 1.4301/304 with powder coating
Vacuum chamber and components Steel 1.4301/304
Main connector PE-UHMW 1000
Drying chamber tube and cover PMMA GS
Seals Low-temperature silicon
Manifold drying rack Steel 1.4301/304
Manifold valves Natural rubber, PP
Cooling medium circuit Copper for freezing applications to EN
Vacuum clips Aluminium
Condensate drain tube Silicone
Condensate drain, ventilation and control
valve
Main valve Aluminium with FKM seal
No maximum performance above 25 °C
12735-1
Brass with EPDM seal
18/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 19
BÜCHI Labortechnik AG Transport and storage | 4
4 Transport and storage
4.1 Transport
IMPORTANT
Risk of breakage due to incorrect transportation
Make sure that the instrument is fully dismantled.
Pack every instrument components properly to prevent breakage. Use the original
packaging whenever possible.
Avoid sharp movements during transit.
u After transporting, check the instrument and all glass components for damage.
u Damage that has occurred in transit should be reported to the carrier.
u Keep packaging for future transportation.
4.2 Storage
u Make sure that the ambient conditions are complied with (see Technical data).
u Wherever possible, store the device in its original packaging.
u After storage, check the device, all glass components, seals and tubing for dam-
age and replace if necessary.
4.3 Lifting the instrument
WARNING
Danger due to incorrect transportation
The possible consequences are crushing injuries, cuts and breakages.
u The instrument should be transported by four persons at the same time.
u Lift the instrument at the points indicated.
Operation Manual LyovaporTM L-200 / L-200 Pro 19/96
Page 20
4 | Transport and storage BÜCHI Labortechnik AG
2
1
4
3
Fig.9: Lifting the instrument
1 Instrument 2 Feet
3 Equipment trolley 4 Castor brakes on trolley
Precondition:
R Make sure that the castor brakes on the equipment trolley are locked on.
u Lift the instrument – this requires four persons each lifting at one of the points indi-
cated on the front and rear of the instrument.
u Set the instrument down on the equipment trolley.
20/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 21
BÜCHI Labortechnik AG Installation | 5
5 Installation
5.1 Installation site
IMPORTANT
Instrument damaged if switched on too early.
After transporting, wait twelve hours before switching on the instrument. The fluid in
the cooling system requires twelve hours to collect in the refrigerant compressor.
The installation site must meet the following requirements:
Firm, level surface
Minimum space requirement: 520 mm x 645 mm x 510 mm (W x D x H).
Take into account the maximum product dimensions and weight.
Take into account the 1100 mm operating height of the drying attachments.
Clearance on each side of the instrument must be at least 30 cm. This clearance
ensures air circulation and prevents the instrument from overheating.
Do not place loose papers or cloths below or to the sides of the instrument, as
these could impede the air circulation if drawn in.
Operate the instrument at an ambient temperature of +15°C to +30°C.
Do not expose the instrument to any external thermal loads, such as direct solar
radiation.
When installing the instrument, make sure that the feet do not bend.
When mounting on an instrument cart, place the feet of the instrument into the sup-
ports on the instrument cart.
NOTE
Make sure that the power supply can be interrupted at any time during an emergency.
5.2 Securing against earthquakes
The Lyovapor™ L-200 has an earthquake fixing point to protect the device against
falling.
Operation Manual LyovaporTM L-200 / L-200 Pro 21/96
Page 22
5 | Installation BÜCHI Labortechnik AG
1
Fig.10: Lyovapor™ L-200
1 Lashing mount
u Tie the lashing mount to a fixed point using strong cord or a wire.
5.3 Putting the instrument in operation
IMPORTANT
Instrument damaged if restarted too early
Wait ten minutes before restarting the instrument. The oil in the refrigerant compressor requires ten minutes to return to the collection tank.
5.3.1 Preparing the instrument
u Clean the instrument with a damp cloth before commissioning.
u Check all sealing surfaces for scratches, dust, and cleanliness.
5.3.2 Establishing electrical connections
NOTE
Observe the regulatory provisions when connecting the Lyovapor™ to power supply.
4 Use external main switches (e.g., emergency off) in accordance with the stan-
dards IEC 60947-1 and IEC 60947-3.
4 Use additional electrical safety features (e.g., residual-current circuit breakers) to
comply with local laws and regulations.
The power supply must fulfill the following conditions:
1. Provide the mains voltage and frequency specified on the type plate of the instrument.
2. Be designed for the load imposed by the instruments connected.
3. Be equipped with suitable fuses and electrical safety features.
4. Be equipped with a proper grounding.
22/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 23
BÜCHI Labortechnik AG Installation | 5
IMPORTANT
Risk of property damage and diminished performance due to use of unsuitable power cables.
The power supply cables supplied with the product by BUCHI precisely match the requirements of the device. If other power cables that do not meet those requirements
are used, the device may be damaged and/or its performance diminished.
u Use only the power supply cables supplied with the product or ordered separately
from BUCHI.
u If using any other power supply cables, make sure that they match the specifica-
tions on the type plate.
u Make sure that all connected devices are grounded.
u If an extension lead is required, make sure that it is earthed and has a suitable
power rating.
u Make sure that the power plug is freely accessible at all times.
u Insert the power cable into the connection labeled Power IN on the back of the in-
strument.
u Insert the power plug into the power socket.
Operation Manual LyovaporTM L-200 / L-200 Pro 23/96
Page 24
5 | Installation BÜCHI Labortechnik AG
5
4
3
2
1
4
5
6
7
6
5.3.3 Assembling the cross fitting (optional accessory)
The cross-pipe enables attachment of multiple additional valves to the instrument.
Fig.11: Fitting the cross-pipe
1 Vacuum connection 2 Seal, ISO-KF 25
3 Clamp, ISO-KF 25 4 90° elbow
5 Clamp, ISO-KF 16 6 Seal, ISO-KF 16
7 Cross-pipe
u Switch the On/Off master switch to Off.
u Fit the cross-pipe (7) and seal (2) to the vacuum connection (1) and fix with the
clamp (3).
u Fit the 90° elbow (4) and seal (6) to a side connection of the cross-pipe (7) and fix
with the clamp (5).
u Repeat Step 3 for the second side connection of the cross-pipe.
24/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 25
BÜCHI Labortechnik AG Installation | 5
6
3
2
1
5
1
2
4
5.3.4 Assembling the main valve (optional accessory)
The main valve regulates the vacuum generated by the vacuum pump. The main
valve is connected between the instrument and the vacuum pump.
Fig.12: Fitting the main valve
1 Clamp, ISO-KF 25 2 Seal, ISO-KF 25
3 Cross-pipe, ISO-KF 25 (optional) 4 Arrow (direction of flow)
5 Vacuum tubing 6 Main valve
u Switch the On/Off master switch to Off.
u Fit the main valve (6) with the arrow (4) pointing in the direction of flow (towards
the vacuum pump) and seal (2) onto the cross-pipe (3) and fix it with the clamp
(1).
u Fit the vacuum tubing (5) and seal (2) onto the main valve outlet and fix it with the
clamp (1).
u Plug the main valve electrical connector into the socket marked Main Valve.
NOTE
The vacuum pump can also be connected directly to the Lyovapor™. If the vacuum
pump is connected directly to the Lyovapor™, the vacuum cannot be regulated.
Manual switch on the main valve
Use the main valve manual switch to set the vacuum control mode.
Operation Manual LyovaporTM L-200 / L-200 Pro 25/96
Page 26
5 | Installation BÜCHI Labortechnik AG
2
1
Fig.13: Manual switch on main valve
1 Main valve 2 Manual switch on main valve
Manual switch positions
Manual switch position Meaning
R Pressure-regulating valve and venting valve are
connected.
u The vacuum is regulated by the pressure-regulat-
ing valve and venting valve.
R Pressure-regulating valve and venting valve are
not connected.
u The vacuum is regulated by the main valve.
R The main valve manual switch is depressed.
u As long as the main valve manual switch is de-
pressed, vacuum regulation is deactivated.
The vacuum is not regulated.
26/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 27
BÜCHI Labortechnik AG Installation | 5
4
32
1
5.3.5 Assembling pressure sensor PPG010 (optional accessory)
The pressure sensor measures the pressure in the ice condenser.
To protect against damage in transit, the pressure sensor is supplied pre-calibrated in
the original packaging.
Fig.14: Fitting the pressure sensor
1 Pressure sensor PPG010 2 Clamp, ISO-KF 16
3 Seal, ISO-KF 16 4 Connection, ISO-KF 16
u Switch the On/Off master switch to Off.
u Remove the shipping cap from the connection (4).
u Fit the pressure sensor (1) and seal (3) to the connection (4) and fix with the
clamp (2).
u Plug the pressure sensor electrical connection into the socket marked Internal
Vacuum Sensor.
u Select the sensor from the submenu [Settin gs ] on the control panel.
Operation Manual LyovaporTM L-200 / L-200 Pro 27/96
Page 28
5 | Installation BÜCHI Labortechnik AG
4
32
1
5
5.3.6 Assembling the venting valve (optional accessory)
The venting valve vents the instrument after the freeze-drying process is completed.
Fig.15: Fitting the venting valve
1 90° elbow, ISO-KF 16 2 Seal, ISO-KF 16
3 Clamp, ISO-KF 16 4 Venting valve
5 Venting valve cable and connection
u Switch the On/Off master switch to Off.
u Fit the cross-pipe and 90° elbow. See Chapter5.3.3 "Assembling the cross fitting
(optional accessory)", page24
u Fit the venting valve (4) and seal (2) to the 90° elbow (1) and fix with the clamp
(3).
u Plug the venting valve electrical connection (4) into the socket marked Aeration
Valve.
28/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 29
BÜCHI Labortechnik AG Installation | 5
21 3 4 5
5.3.7 Assembling the pressure regulating valve (optional accessory)
The pressure regulating valve provides additional pressure regulating capability during the freeze-drying process. It regulates the vacuum by the introduction of external
air.
Fig.16: Fitting the pressure-regulating valve
1 90° elbow, ISO-KF 16 2 Clamp, ISO-KF 16
3 Seal, ISO-KF 16 4 Pressure regulating valve
5 Pressure-regulating valve cable and
connector
u Switch the On/Off master switch to Off.
u Fit the cross-pipe and 90° elbow (1). See Chapter5.3.3 "Assembling the cross fit-
ting (optional accessory)", page24
u Fit the pressure-regulating valve (4) and seal (3) to the 90° elbow (1) and fix with
the clamp (2).
u Plug the pressure-regulating valve electrical connector (5) into the socket marked
Regulation Valve.
Operation Manual LyovaporTM L-200 / L-200 Pro 29/96
Page 30
5 | Installation BÜCHI Labortechnik AG
2
1
5.3.8 Assembling the alternative pressure sensor (optional accessory)
Instead of the standard pressure sensor, an alternative pressure sensor can be used.
Fig.17: Fitting alternative pressure sensor
1 Connection, ISO-KF 16 2 External pressure sensor connection
u Switch the On/Off master switch to Off.
u Remove the blanking cap from the connection (1).
u Connect the pressure sensor to the connection (1).
u Plug the pressure sensor connecting lead into the socket marked External Vac-
uum Sensor (2).
u Select the sensor from the submenu [Settin gs ] on the control panel.
30/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 31
BÜCHI Labortechnik AG Installation | 5
1
2
3
5.3.9 Preparing the condensate drain hose
CAUTION
Risk of scalding by hot water
u Make sure the condensate drain hose is not loose.
IMPORTANT
Contamination of the device
Escaping condensate can contaminate the instrument.
u Fit the condensate drain hose with a downward slope. Make sure that the drain
hose is not immersed in the condensate.
u Seal the condensate drain hose with the end plug as soon as cleaning of the in-
strument is completed.
Fig.18: Condensate drain hose
1 Rubber ring 2 Condensate drain hose
3 End plug
The condensate drain hose is on the side of the instrument. The drain hose is sealed
with an end plug. The condensation is drained off through this drain hose after completion of the freeze-drying process.
u Pull the drain hose (2) together with end plug (3) out of the side panel of the instru-
ment.
u Remove the end plug.
u Direct the drain hose into a waste outlet or place a container underneath it.
Operation Manual LyovaporTM L-200 / L-200 Pro 31/96
Page 32
5 | Installation BÜCHI Labortechnik AG
2
1
5.4 Commissioning the vacuum pump
The vacuum pump evacuates the top-mount drying rack during the freeze-drying
process.
NOTE
To increase the service life of the vacuum pump, operate the vacuum pump with an
open gas ballast valve.
NOTE
Prepare the vacuum pump according to the manufacturer's instructions. See relevant
documentation.
Fig.19: Connections for vacuum pump
1 Vacuum pump connection 2 Vacuum tube connection,
ISO-KF 25
u Switch the On/Off master switch to Off.
u Connect the vacuum pump vacuum tube to the vacuum tube connection (2).
u Plug the vacuum pump electrical connection into the socket marked Vacuum
Pump.
5.5 Assembling the drying attachments
A top-mount drying rack completes the ice condenser, turning it into a ready-to-use
freeze-dryer.
5.5.1 Fitting the 300 mm dia. O-ring
Do not use any sharp objects when fitting the top-mount drying racks.
Before fitting the top-mount drying racks, fit the 300mm O-ring over the ice condenser.
32/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 33
BÜCHI Labortechnik AG Installation | 5
1
2
Fig.20: Fitting the 300mm dia. O-ring
1 Groove above ice condenser 2 O-ring, dia. 300mm
u Make sure that the groove above the ice condenser (1) is clean, free of dust and
not scratched.
u Check the 300mm dia. O-ring (2) for damage and grease it with vacuum grease.
u Place the 300mm dia. O-ring (2) in the groove above the ice condenser (1).
5.5.2 Fitting the acrylic drying chamber
The instrument can be completed with the acrylic drying chamber.
Operation Manual LyovaporTM L-200 / L-200 Pro 33/96
Page 34
5 | Installation BÜCHI Labortechnik AG
3
2
6
1
5
4
Fig.21: Fitting the acrylic drying chamber
1 Cover 2 O-ring, dia. 300mm
3 Cylinder 4 Intermediate plate
5 Ice condenser 6 Rack
Precondition:
R The 300 mm O-ring is fitted in the groove above the ice condenser.
u Remove all parts of the drying chamber from the packaging and check for dam-
age.
u Place the intermediate plate (4) on the ice condenser (5).
u Place the rack (6) on the intermediate plate (4).
u Locate the cylinder (3) in the groove above the ice condenser (5).
u Check the 300mm dia. O-ring (2) for damage and grease it with vacuum grease.
u Place the 300mm dia. O-ring (2) in the groove in the lid.
u Place the lid (1) on the cylinder (3).
5.5.3 Fitting the manifold acrylic drying chamber
The instrument can be completed with the manifold acrylic drying chamber.
34/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 35
BÜCHI Labortechnik AG Installation | 5
3
2
6
1
5
4
Fig.22: Fitting the manifold acrylic drying chamber
1 Cover 2 O-ring, dia. 300mm
3 Cylinder 4 Intermediate plate
5 Ice condenser 6 Rack
Precondition:
R The 300 mm O-ring is fitted in the groove above the ice condenser.
u Remove all parts of the drying chamber from the packaging and check for dam-
age.
u Fit the manifold valves to the lid. See Chapter5.5.8 "Assembling manifold valves",
page42.
u Place the intermediate plate (4) on the ice condenser (5).
u Place the rack (6) on the intermediate plate (4).
u Locate the cylinder (3) in the groove above the ice condenser (5).
u Check the 300mm dia. O-ring (2) for damage and grease it with vacuum grease.
u Place the 300mm dia. O-ring (2) in the groove in the lid.
u Place the lid (1) on the cylinder (3).
5.5.4 Fitting the stopper acrylic drying chamber
The instrument can be completed with the stopper acrylic drying chamber.
Operation Manual LyovaporTM L-200 / L-200 Pro 35/96
Page 36
5 | Installation BÜCHI Labortechnik AG
4
3
8
9
2
1
7
6
5
Fig.23: Fitting the stopper acrylic drying chamber
1 Hand wheel 2 Cover
3 O-ring, dia. 300mm 4 Cylinder
5 Springs 6 Ice condenser
7 Intermediate plate 8 Rack
9 Hook
Precondition:
R The 300 mm O-ring is fitted in the groove above the ice condenser.
u Remove all parts of the drying chamber from the packaging and check for dam-
age.
u Locate the springs (5) in the holes on the ice condenser (6).
u Place the intermediate plate (7) on the springs (5).
u Place the rack (8) on the intermediate plate (7).
u Locate the cylinder (4) in the groove above the ice condenser (5).
u Screw the hand wheel (1) upwards until the plate inside the lid has pressed the
hooks (9) all the way in.
u Check the 300mm dia. O-ring (3) for damage and grease it with vacuum grease.
u Place the 300mm dia. O-ring (3) in the groove in the lid (2).
u Place the lid (2) on the cylinder (4).
5.5.5 Assembling the manifold drying rack
The instrument can be completed with a manifold drying rack.
36/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 37
BÜCHI Labortechnik AG Installation | 5
1
3
4
5
2
6
The manifold drying rack enables freeze-drying of samples in flasks. The manifold
drying rack is a modular, expandable design.
Fig.24: Manifold drying rack
1 Manifold valve 2 Manifold drying rack
3 Base plate 4 Seal, ISO-KF 40
5 Clamp, ISO-KF 40 6 Connection, ISO-KF 40
Precondition:
R The 300 mm O-ring is fitted in the groove above the ice condenser.
u Remove all parts of the manifold drying rack from the packaging and check for
damage.
u Fit the manifold valves (1). See Chapter5.5.8 "Assembling manifold valves",
page42.
u Place the base plate (3) on the ice condenser.
u Place the seal (4) on the connection (6).
u Fit the manifold drying rack (2) onto the seal and fix it with the clamp (5).
5.5.6 Fitting the non-heatable shelf
Shelves can be fitted in the drying chambers. The shelves allow the freeze-drying of
samples in vials or as loose samples. The shelves slide into a rack inside the drying
chamber.
Operation Manual LyovaporTM L-200 / L-200 Pro 37/96
Page 38
5 | Installation BÜCHI Labortechnik AG
1
2
5
6
1
4
3
Fig.25: Non-heatable shelf
1 Non-heatable shelf
Sliding the shelves into the rack
Fig.26: Non-heatable shelf in rack
1 Rack 2 Slot for shelf
3 Stop 4 Connections for shelves
5 Non-heatable shelf 6 Lug
Precondition:
R The rack is mounted on top of the ice condenser.
u Slide the shelf (5) into a slot (2) in the rack (1).
u Make sure that the shelf (5) is secured by the lug (6).
u Fit the cylinder and the lid.
38/96
Operation Manual LyovaporTM L-200 / L-200 Pro
Page 39
BÜCHI Labortechnik AG Installation | 5
1
3
2
5.5.7 Fitting heatable shelves
Shelves can be fitted in the drying chambers. The shelves allow the freeze-drying of
samples in vials or as loose samples. The shelves slide into a rack inside the drying
chamber.
Fig.27: Heatable shelf
1 Heatable shelf 2 Connection for temperature sensor
3 Electrical connector for heatable
shelves
Heatable shelves with controlled temperature.
◦ The heatable shelves are connected to the instrument by a connecting lead.
◦ As an additional option, a temperature sensor for monitoring the product temper-
ature can be connected to the temperature sensor connection.
Operation Manual LyovaporTM L-200 / L-200 Pro 39/96
Page 40
5 | Installation BÜCHI Labortechnik AG
2
7
8
1
6
5
4
3
Sliding the shelves into the rack
Fig.28: Heatable shelf in rack
1 Rack 2 Slot for shelf
3 Temperature sensor (option) 4 Stop
5 Connections for shelves 6 Electrical connector for heatable shelf
7 Heatable shelf 8 Lug
Precondition:
R The rack is mounted on top of the ice condenser.
u Slide the shelf (7) into a shelf slot (2) in the rack (1).
u Make sure that the shelf (7) is secured by the lug (8).
u Plug the connecting lead (6) into one of the supply sockets (5).
u Fit the cylinder and the lid.
40/96
Operation Manual LyovaporTM L-200 / L-200 Pro
Page 41
BÜCHI Labortechnik AG Installation | 5
2
3
1
2
3
1
Plugging in the heatable shelf connector
Fig.29: Plugging in heatable shelf
1 Electrical connector for heatable shelf 2 Connections for shelves
3 Ring
Precondition:
R The shelf is slotted into the rack.
u Push the electrical connector (1) onto one of the shelf connections (2) while simul-
taneously twisting the ring (3) anti-clockwise.
The shelf is connected.
Unplugging the heatable shelf connector
Fig.30: Unplugging heatable shelves
1 Electrical connector for heatable shelf 2 Connections for shelves
3 Ring
u Press the electrical connector (1) into the shelf connection (2) while simultane-
ously twisting the ring (3) clockwise.
Operation Manual LyovaporTM L-200 / L-200 Pro 41/96
Page 42
5 | Installation BÜCHI Labortechnik AG
3
2
1
7
6
5
4
1
2
Temperature sensor connector
Fig.31: Temperature sensor connector
1 Heatable shelf 2 Connection for temperature sensor
3 Marking on temperature sensor con-
nection
4 Marking on temperature sensor con-
nector
5 Ring 6 Temperature sensor connector
7 Temperature sensor
Plugging in the temperature sensor connector:
u Twist the temperature sensor connector (4) so that the markings (3) and (4) are in
line.
u Push the temperature sensor connector (4) onto the temperature sensor connec-
tion (2).
Unplugging the temperature sensor connector:
u Pull on the ring (3).
5.5.8 Assembling manifold valves
The manifold valves are used for freeze-drying samples in flasks on the manifold
acrylic drying chamber or the manifold drying rack.
Fig.32: Fitting manifold valves
1 Connection on the top-mount drying
2 Manifold valve
rack
42/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 43
BÜCHI Labortechnik AG Installation | 5
1
2
A
B
C
5
4
3
2
1
u Remove manifold valve (2) from the packaging.
u Fit manifold valve (2) onto the connection on the top-mount drying rack (1).
Manifold valve settings
The lever on a manifold valve can be set to the following positions:
Fig.33: Manifold valve
1 Manifold valve 2 Lever
Position Function
A: Lever pointing up The connected vessel is evacuated.
B: Lever pointing left The manifold valve is closed.
C: Lever pointing down The connected vessel is vented.
Pre-evacuation of a connected vessel
Pre-evacuating a connected vessel using an additional vacuum.
Fig.34: Evacuation adaptor
1 Manifold valve 2 Lever
3 Evacuation adaptor 4 Tube clip
Operation Manual LyovaporTM L-200 / L-200 Pro 43/96
5 Vacuum tubing
Page 44
5 | Installation BÜCHI Labortechnik AG
Precondition:
R The manifold valve is closed.
u Fit the evacuation adaptor (3) onto the lever (2).
u Fit the vacuum tube (5) onto the evacuation adaptor (3).
u Fix the vacuum tube with the tube clip (4).
u Connect a vacuum to the vacuum tube (5).
u Connect a vessel to the manifold valve.
u Turn the lever (2) downwards.
The vessel is evacuated.
44/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 45
BÜCHI Labortechnik AG Operating the control panel | 6
4
32
1
6
5
6 Operating the control panel
This section describes the operation of the instrument using the control panel.
CAUTION
Risk of injury from glass splinters
Sharp objects can damage the display.
u Keep sharp objects away from the display.
6.1 Layout of the control panel
Fig.35: Layout of the control panel
No. Description Function
1 Status bar Shows the current status of the instrument.
2 Menu bar Shows symbols representing the menus.
3 Content area Shows current settings, submenus or actions
4 Function bar Shows functions that can be performed ac-
5 Navigation control Used for navigating the user interface.
6 Function buttons Pressing a function button performs the as-
6.2 Function bar
The function bar shows available functions according to the current operation.
The functions on the function bar are executed by tapping the relevant function buttons or pressing the navigation control.
depending on current operation.
cording to the current operation.
Pressing the control performs the assigned
function on the function bar.
signed function on the function bar.
Operation Manual LyovaporTM L-200 / L-200 Pro 45/96
Page 46
6 | Operating the control panel BÜCHI Labortechnik AG
General function buttons
Symbol Description Meaning
[Back] The display reverts to the previous
view.
[Cancel ] Cancels an operation.
[Add to f avourites ] Adds the selected item to the
[Favour it es] menu.
[Remove f rom
favouri te s]
Removes the selected item from the
[Favour it es] menu.
[Confir m] Confirms an entry.
[Edit] Allows the selected item to be
edited.
[Menu] Allows selection of a menu from the
menu bar using the navigation con-
trol.
[Save] Saves the setting.
Process control function buttons
Symbol Description Meaning
6.3 Menu bar
The menus are represented by symbols on the menu bar. Navigation through the
menus is by input controls.
The following menus are available:
Menu
symbol
[Defros t] Defrosts the ice condenser.
[Aerate ] Vents the system.
[Shut d ow n] The instrument shuts down.
[Start] Starts the freeze-drying process.
[Start co nditionin g] Starts the conditioning phase.
[Skip] Skips the current process.
Meaning Submenu/Action
[Start] menu Process control parameters
[Favour it es] menu Bookmarks for individual entry points
46/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 47
BÜCHI Labortechnik AG Operating the control panel | 6
Menu
symbol
6.3.1 Start menu
On the [Start] menu, parameters can be set manually.
Changing parameters
u Select a parameter by turning the navigation control.
The control panel highlights the selected parameter in green.
u Tap the function [Edit] on the function bar.
The control panel highlights the selected parameter in black.
u To increase or decrease the figure, turn the navigation control clockwise or anti-
clockwise.
u Tap the function [Save] on the function bar.
The setting is saved.
Meaning Submenu/Action
[Config ur ation] menu Process settings
Settings
Servicing
Service
System information
[Messag es ] menu Notifications
Logbook
6.3.2 Favourites menu
The [Favour it es] menu allows you to define submenus and actions as bookmarks.
Adding a favourite
u Navigate to a submenu or action.
u Tap the function [Add to f avourit es ] on the function bar.
The user interface switches to the [Favour it es] menu and displays the favourite
created.
Removing a favourite
u On the [Favour it es] menu, navigate to the favourite you wish to remove.
u Tap the function [Remove f rom fav ou ri tes] on the function bar.
The favourite is removed.
6.3.3 Configuration menu
On the [Config ur ation] menu, you can enter a variety of settings and retrieve information.
Process settings submenu
The submenu [Proces s settings] contains functions for automatic process control.
Action Option Explanation
[Vacuum t est after con di tioning]
[Defros t before
conditi on ing]
Off/On Automatic vacuum test after the con-
ditioning phase
Off/On Automatic condenser defrosting be-
fore the conditioning phase
Settings submenu
The submenu [Settin gs ] contains system settings for the instrument.
Operation Manual LyovaporTM L-200 / L-200 Pro 47/96
Page 48
6 | Operating the control panel BÜCHI Labortechnik AG
Action Option Explanation
[Mobile c onnection pa ss word]
[Mobile c onnection QR c ode]
View The control panel shows a password
for entry in the BUCHI Monitor app.
View The control unit shows a QR code
for reading by the BUCHI Monitor
app.
[Langua ge ] Choice of display lan-
guage on the control
panel
The following languages are avail-
able:
English/German/French/Italian/
Spanish/Russian/Portuguese/Japa-
nese/Chinese/Indonesian/Korean
[Temper at ure
unit]
Choice of unit for indication of temperatures
The following units are available:
°C (Celsius)/°F (Fahrenheit)/K
(Kelvin)
[Pressu re unit] Choice of unit for indi-
cation of the vacuum
The following units are available:
HPa (hectopascals), mbar (mil-
libars), torr (= torr), mTorr (= milli-
torr), mmHg (millimetres of mercury)
[Date] Date input Enter in sequence: Year, month,
day. Apply the settings by pressing
[Save].
[Time] Time input Enter in sequence: Minutes, hours.
Apply the settings by pressing
[Save].
[Pressu re sensor]
Pressure sensor selection
The following pressure sensors are
available:
None, Inficon PPG010, Inficon
Porter CDG020D, Inficon PSG 550
[Vacuum p ump
oil cha ng e]
Enter setting Enter the oil change interval recom-
mended by the manufacturer.
[Button t one] Off/On Setting for audible signal in re-
sponse to input controls.
[Displa y brightness]
Enter setting Display illumination level in %: 0 -
100
[Networ k] Enter value The following parameters can be
edited:
Device name/MAC address/DHCP/
System IP address/Subnet mask/
Gateway/DNS server/BUCHI Cloud/
Server IP address
[Delete a pp connection ]
Confirmation question Resets external connections to the
instrument.
Submenu Maintenance
The submenu [Mainte na nce] contains tests for maintaining the instrument.
Action Option Explanation
[Leak t es t] Perform leak test See section Chapter9.2 "Performing
a leak test", page84
48/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 49
BÜCHI Labortechnik AG Operating the control panel | 6
Action Option Explanation
[Vacuum t est] Perform vacuum test See Chapter9.3 "Performing a vac-
uum test", page84
Submenu Service
The submenu [Servic e] contains information on the individual freeze-dryer components.
Action Option Explanation
[Refrig er ant circuit]
View The following information on the re-
frigerant circuit is available:
Hours of duty
Compressor
Ice condenser inlet temperature
Ice condenser outlet temperature
High-pressure safety cut-out
Low-pressure safety cut-out
[Vacuum s ystem]
View The following information on the vac-
uum pump is available:
Pump hours of duty
Pump oil hours of duty
Pressure in the ice condenser
Main valve
Vacuum pump
Venting valve
Regulating valve
[Defros ti ng system]
Display/entry of figures The following information on the de-
frosting system is available:
Hours of duty
Drain valve open/closed
Submenu System Information
The submenu [System i nformat io n] contains details of the connected components
and information on network connection diagnosis.
Action Option Explanation
[Contro l panel] View The following information on the
control panel is available:
Serial number
Firmware version
Hours of duty
Status
PCB Temperature
24V power supply
5V power supply
Operation Manual LyovaporTM L-200 / L-200 Pro 49/96
Page 50
6 | Operating the control panel BÜCHI Labortechnik AG
Action Option Explanation
[L-200] View The following information on the
L-200 is available:
Serial number
Firmware version
Hours of duty
Status
PCB Temperature
48V power supply
24V power supply
5V power supply
3.3V power supply
[Networ k diagnostics ]
View/Enter settings The following network diagnosis in-
formation is available:
Network interruptions
Event list
6.3.4 Messages menu
The [Messag es ] menu shows the current instrument messages and the instrument's
message history.
The following message types are possible:
I = Information
W = Warning
E = Error
Submenu Notifications
The submenu [Notifi ca tions] shows the currently pending messages.
List of pending messages.
The lists contains only unconfirmed messages together with date and time.
Submenu Logbook
The submenu [Logboo k] shows the instrument's message history.
Logbook:
List of the last 30 messages.
Every occurrence is shown with date and time.
The following status types are possible:
x = Confirmed
< = Sent
> = Received
6.4 Status bar
The status bar shows the status of the instrument.
The following statuses are possible:
50/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 51
BÜCHI Labortechnik AG Operating the control panel | 6
Indication on status bar
View Status
Unload / Load Before the freeze-drying process:
Load the top-mount drying rack with a frozen
sample.
After the freeze-drying process:
Remove the dried sample from the top-mount
drying rack.
Aerating The system is venting.
Shutting down The instrument is shutting down.
Defrosting The instrument is defrosting.
Standby The instrument is in energy-saving mode.
Conditioning The instrument is starting up.
Warming up pump The vacuum pump is being brought up to operat-
ing temperature.
Vacuum Test The instrument is performing a vacuum test.
Leak Test The instrument is performing a leak test.
Manual Drying The instrument is in the course of a manual
freeze-drying process.
Recovering The system is in the process of recovering from a
power failure.
The current parameters of the freeze-drying
process are being re-established.
Symbols on the status bar
Symbol Status
The instrument is connected to the BUCHI Cloud.
The instrument is defrosting.
The instrument is starting up.
The instrument is in energy-saving mode.
Before the freeze-drying process:
Load the top-mount drying rack with a frozen
sample.
After the freeze-drying process:
Remove the dried sample from the top-mount
drying rack.
The vacuum pump is being brought up to operating temperature.
The instrument is performing a vacuum test or a
leak test.
The instrument is in the course of a manual
freeze-drying process.
Operation Manual LyovaporTM L-200 / L-200 Pro 51/96
Page 52
6 | Operating the control panel BÜCHI Labortechnik AG
6.5 Carrying out freeze-drying
6.5.1 Preparing the instrument
Time
re-
approx.
30min
quired:
NOTE
The conditioning phase can be skipped by tapping [Skip] on the function bar.
Navigation path
➔ Start
u Navigate to the [Start] menu via the navigation path.
u Tap the function [Start co ndition in g] on the function bar.
The temperature in the ice condenser decreases to operating temperature.
The vacuum pump is brought up to operating temperature.
After completion of the conditioning phase, the status bar shows the status Un-
load / Load.
6.5.2 Starting freeze-drying
CAUTION
Risk of skin burns from touching parts of the ice condenser after completion of conditioning.
u Wear protective gloves when working on the instrument after the conditioning
phase.
Navigation path
➔ Start
Precondition:
R The instrument has been prepared.
u Fit a top-mount drying rack. See Chapter5.5 "Assembling the drying attachments",
page32.
u Load the top-mount drying rack with frozen preparations.
u Navigate to the [Start] menu via the navigation path.
u Enter the required settings for the process parameters.
u Tap the function [Start] on the function bar.
The freeze-drying process starts.
The control panel shows the [Start] menu with a black background.
The status bar shows a clock counting up and the status Manual Drying.
The system evacuates to the set pressure.
6.5.3 Editing parameters while the process is running
Navigation path
➔ Start
Precondition:
52/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 53
BÜCHI Labortechnik AG Operating the control panel | 6
R The freeze-drying process has been started.
u Navigate to the [Start] menu via the navigation path.
u Navigate to the desired parameter using the navigation control.
u Tap the function [Edit] on the function bar.
The control panel highlights the selected parameter in white.
u Turn the navigation control to increase or decrease the parameter setting.
u Tap the function [Save] on the function bar.
The setting is saved.
6.5.4 Ending freeze-drying
Navigation path
➔ Start
Precondition:
R The sample is dry.
u Navigate to the [Start] menu via the navigation path.
u Tap the function [Aerate ] on the function bar.
u Answer YES to the confirmation question.
The system is vented.
The status bar shows the status Aerating.
u As soon as the status bar shows the status Unload / Load, remove the dried sam-
ple from the drying rack.
6.5.5 Shutting down the instrument
Time
40min
required:
IMPORTANT
Do not use force to remove the ice from the ice condenser.
Navigation path
➔ Start
Precondition:
R The freeze-drying process has ended.
u Position the condensate drain hose so that the condensate can be drained off.
See Chapter5.3.9 "Preparing the condensate drain hose", page31
u Navigate to the [Start] menu via the navigation path.
u Tap the function [Shut d ow n] on the function bar.
The instrument shuts down.
The status bar shows the remaining time and the status Shutting down.
After the instrument has shut down, the status bar shows the remaining time and
the status Defrosting.
Operation Manual LyovaporTM L-200 / L-200 Pro 53/96
Page 54
7 | Operating Pro control panel BÜCHI Labortechnik AG
5
4
3
2
1
7 Operating Pro control panel
This section describes the operation of the instrument using the Pro control panel.
CAUTION
Risk of injury from glass splinters
Sharp objects can damage the display.
u Keep sharp objects away from the display.
7.1 Layout of Pro control panel
Fig.36: Layout of Pro control panel
No. Description Function
1 Status bar Shows the current status of the instrument.
2 Menu bar Shows symbols representing the menus.
3 Content area Shows current settings, submenus or actions
4 Function bar Shows functions that can be performed ac-
5 Navigation control Used for navigating the user interface. Press-
7.2 Function bar
The function bar shows functions that can be performed according to current operation.
The functions on the function bar are executed by tapping the relevant function buttons or pressing the navigation control.
General function buttons
Symbol Description Meaning
depending on the current operation.
cording to the current operation
ing the control performs the assigned function on the function bar.
[Back] The display reverts to the previous
view.
54/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 55
BÜCHI Labortechnik AG Operating Pro control panel | 7
Symbol Description Meaning
[Cancel ] Cancels an operation.
[Add to f avourites ] Adds the selected item to the
[Favour it es] menu.
[Remove f rom
favouri te s]
Removes the selected item from the
[Favour it es] menu.
[Confir m] Confirms an entry.
[Edit] Allows the selected item to be
edited.
[Menu] Allows selection of a menu from the
menu bar using the navigation control.
[Save] Saves the setting.
Process control function buttons
Symbol Description Meaning
[Defros t] Defrosts the ice condenser.
[Aerate ] Vents the system.
[Shut d ow n] The instrument shuts down.
[Start] Starts the freeze-drying process.
[Start co nditionin g] Starts the conditioning phase.
[Manual ] Switches to manual freeze-drying.
[Method ] Switches to freeze-drying with pro-
grammable parameters.
[New] Creates a new method
[Right] Moves the selection to the right.
[Left] Moves the selection to the left.
[Progre ss ion] Graphical display of method pro-
gression showing pressure and temperature details.
[Activa te ] Confirms selection of a method.
[Skip] Skips the current process.
[Delete ] Deletes the selected method or step.
Operation Manual LyovaporTM L-200 / L-200 Pro 55/96
Page 56
7 | Operating Pro control panel BÜCHI Labortechnik AG
7.3 Menu bar
The menus are represented by symbols on the menu bar. Navigation through the
menus is by the input controls.
The following menus are available:
Menu
symbol
7.3.1 Start menu
On the [Start] menu, parameters can be set manually.
Setting parameters using the navigation control
u Select a parameter by turning the navigation control.
The control panel highlights the selected parameter in green.
u Tap the function [Edit] on the function bar.
The control panel highlights the selected parameter in black.
u To increase or decrease the figure, turn the navigation control clockwise or anti-
clockwise.
u Press the navigation control.
The setting is saved.
The control panel highlights the new setting in green.
Meaning Submenu/Action
Start menu Process control parameters
Favourites menu Bookmarks for individual entry points
Method menu For saving freeze-drying methods
Editing and activating
Configuration menu Process settings
Settings
End point determination
Maintenance
Service
System information
Messages menu Notifications
Logbook
Setting parameters using the touch-screen
u Select the parameter by tapping the control panel screen.
The control panel shows a dialog box with a numeric input box.
The control panel highlights the selected parameter in black.
u Enter the value in the numeric input box.
u Tap the function [Save] on the function bar.
The setting is saved.
The dialog box closes.
The control panel highlights the new setting in green.
7.3.2 Favourites menu
The [Favour it es] menu allows you to define submenus and actions as favourites.
56/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 57
BÜCHI Labortechnik AG Operating Pro control panel | 7
Adding a favourite
u Navigate to a submenu or action.
u Tap the function [Add to f avourit es ] on the function bar.
The user interface switches to the [Favour it es] menu and displays the favourite
created.
Removing a favourite
u On the [Favour it es] menu, navigate to the favourite you wish to remove.
u Tap the function [Remove f rom fav ou ri tes] on the function bar.
The favourite is removed.
7.3.3 Method menu
The [Method ] menu allows freeze-drying processes with multiple phases and steps
to be saved. See Chapter7.5 "Editing a method", page62
7.3.4 Configuration menu
On the [Config ur ation] menu, you can enter a variety of settings and retrieve information.
Process settings submenu
The submenu [Proces s settings] contains actions for automatic process control.
Action Option Explanation
[Vacuum t est after con di tioning]
[Leak t es t after
conditi on ing]
[Defros t before
conditi on ing]
Off/On Automatic vacuum test after the con-
ditioning phase
Off/On Automatic leak test after the condi-
tioning phase
Off/On Automatic condenser defrosting be-
fore the conditioning phase
Settings submenu
The submenu [Settin gs ] contains system settings for the instrument.
Action Option Explanation
[Mobile c onnection pa ss word]
[Mobile c onnection QR c ode]
View The control panel shows a password
for entry in the BUCHI Monitor app.
View The control unit shows a QR code
for reading by the BUCHI Monitor
app.
[Langua ge ] Choice of display lan-
guage on the control
panel
The following languages are available:
English/German/French/Italian/
Spanish/Russian/Portuguese/Japanese/Chinese/Indonesian/Korean
[Temper at ure
unit]
Choice of unit for indication of temperatures
The following units are available:
°C (Celsius)/°F (Fahrenheit)/K
(Kelvin)
[Pressu re unit] Choice of unit for indi-
cation of the vacuum
The following units are available:
HPa (hectopascals), mbar (mil-
libars), torr (= torr), mTorr (= millitorr), mmHg (millimetres of mercury)
Operation Manual LyovaporTM L-200 / L-200 Pro 57/96
Page 58
7 | Operating Pro control panel BÜCHI Labortechnik AG
Action Option Explanation
[Date] Date input Enter in sequence: Year, month,
day. Apply the settings by pressing
[Save].
[Time] Time input Enter in sequence: Minutes, hours.
Apply the settings by pressing
[Save].
[Pressu re sensor]
Pressure sensor selection
The following pressure sensors are
available:
None, Inficon PPG010, Inficon
Porter CDG020D, Inficon PSG 550
[Vacuum p ump
oil cha ng e]
Enter setting Enter the oil change interval recom-
mended by the manufacturer.
[Button t one] Off/On Setting for audible signal in re-
sponse to input controls.
[Displa y brightness]
Enter setting Display illumination level in %: 0 -
100
[Networ k] Enter value The following parameters can be
edited:
Device name/MAC address/DHCP/
System IP address/Subnet mask/
Gateway/DNS server/BUCHI Cloud/
Server IP address
[Delete a pp connection ]
Confirmation question Resets external connections to the
instrument.
Submenu End point determination
Action Option Explanation
[Pressu re difference te st ]
[Temper at ure
differe nc e test]
View Shows the current parameters for
the pressure difference test.
View Shows the current parameters for
the temperature difference test.
Submenu Maintenance
The submenu [Mainte na nce] contains tests for maintaining the instrument.
Action Option Explanation
[Leak t es t] Perform leak test See section Chapter9.2 "Performing
a leak test", page84
[Vacuum t est] Perform vacuum test See Chapter9.3 "Performing a vac-
uum test", page84
Submenu Service
The submenu Service contains information on the individual freeze-dryer components.
58/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 59
BÜCHI Labortechnik AG Operating Pro control panel | 7
Action Option Explanation
[Refrig er ant circuit]
View The following information on the re-
frigerant circuit is available:
Hours of duty
Compressor
Ice condenser inlet temperature
Ice condenser outlet temperature
High-pressure safety cut-out
Low-pressure safety cut-out
[Vacuum s ystem]
View The following information on the vac-
uum pump is available:
Pump hours of duty
Pump oil hours of duty
Pressure in the ice condenser
Main valve
Vacuum pump
Venting valve
Regulating valve
[Defros ti ng system]
Display/entry of figures The following information on the de-
frosting system is available:
Hours of duty
Drain valve open/closed
[Drying s helves] View Switches heating for the individual
drying shelves on and off (where
available).
Submenu System Information
The submenu [System i nformat io n] contains details of the connected devices and
information on network connection diagnosis.
Action Option Explanation
[Contro l panel] View The following information on the
control panel is available:
Serial number
Firmware version
Hours of duty
Status
PCB Temperature
24V power supply
5V power supply
Operation Manual LyovaporTM L-200 / L-200 Pro 59/96
Page 60
7 | Operating Pro control panel BÜCHI Labortechnik AG
Action Option Explanation
[L-200] View The following information on the
L-200 is available:
Serial number
Firmware version
Hours of duty
Status
PCB Temperature
48V power supply
24V power supply
5V power supply
3.3V power supply
[Networ k diagnostics ]
View/Enter settings The following network diagnosis in-
formation is available:
Network interruptions
Event list
7.3.5 Messages menu
The [Messag es ] menu shows the current instrument messages and the instrument's
message history.
The following message types are possible:
I = Information
W = Warning
E = Error
Submenu Notifications
The submenu [Notifi ca tions] shows the currently pending messages.
List of pending messages.
The lists contains only unconfirmed messages together with date and time.
Submenu Logbook
The submenu [Logboo k] shows the instrument's message history.
Logbook:
List of the last 30 messages.
Every occurrence is shown with date and time.
The following status types are possible:
x = Confirmed
< = Sent
> = Received
7.4 Status bar
The status bar shows the status of the instrument.
The following statuses are possible:
60/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 61
BÜCHI Labortechnik AG Operating Pro control panel | 7
Indication on status bar
View Status
Unload / Load Before the freeze-drying process:
Load the top-mount drying rack with a frozen
sample.
After the freeze-drying process:
Remove the dried sample from the top-mount
drying rack.
Aerating The system is venting.
Shutting down The instrument is shutting down.
Defrosting The instrument is defrosting.
Standby The instrument is in energy-saving mode.
Conditioning The instrument is starting up.
Warming up pump The vacuum pump is being brought up to operat-
ing temperature.
Vacuum Test The instrument is performing a vacuum test.
Leak Test The instrument is performing a leak test.
Manual Drying The instrument is in the course of a manual
freeze-drying process.
Recovering The system is in the process of recovering from a
power failure.
The current parameters of the freeze-drying
process are being re-established.
Hold The instrument is in the holding phase.
Primary drying The instrument is in the primary drying phase.
Secondary drying The instrument is in the secondary drying phase.
Tempering shelves The instrument is modulating the heatable
shelves to the set temperature.
Symbols on the status bar
Symbol Status
The instrument is defrosting.
The instrument is in energy-saving mode.
The instrument is in the course of a freeze-drying
process using a method.
The instrument is starting up.
The instrument is in the course of a manual
freeze-drying process.
The instrument is connected to the BUCHI Cloud.
Sample protection is active.
Operation Manual LyovaporTM L-200 / L-200 Pro 61/96
Page 62
7 | Operating Pro control panel BÜCHI Labortechnik AG
Symbol Status
Before the freeze-drying process:
Load the top-mount drying rack with a frozen
sample.
After the freeze-drying process:
Remove the dried sample from the top-mount
drying rack.
The vacuum pump is being brought up to operating temperature.
The instrument is performing a vacuum test or a
leak test.
7.5 Editing a method
The Pro control panel can save up to 35 methods. The methods enable the freezedrying process to be automated.
7.5.1 Creating a new method
Navigation path
➔ Method
u Navigate to the [Method ] menu via the navigation path.
u Tap the function [New] on the function bar.
The new method is created.
7.5.2 Changing the name of a method
Navigation path
➔ Method
u Navigate to the [Method ] menu via the navigation path.
u Tap the name of the method that you wish to edit.
The control panel highlights the selected method in green.
u Tap the action [Inform at ion].
The control panel shows the action Information.
u Tap the setting [Name].
The control panel shows a blank box with an alphanumeric input box.
u Enter a name for the method.
u Tap the function [Save] on the function bar.
The new name is saved.
The dialog box closes.
7.5.3 Setting the sample collapse temperature
Navigation path
➔ Method
u Navigate to the [Method ] menu via the navigation path.
u Tap the name of the method that you wish to edit.
The control panel highlights the selected method in green.
u Tap the action [Genera l] .
The control panel shows the action [Genera l] .
62/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 63
BÜCHI Labortechnik AG Operating Pro control panel | 7
u Tap the setting [Sample c ollapse t em peratur e] .
The control panel shows a dialog box with a numeric input box.
u Enter the value in the numeric input box.
u Tap the function [Save] on the function bar.
The setting is saved.
The dialog box closes.
7.5.4 Setting the gas type
Navigation path
➔ Method
u Navigate to the [Method ] menu via the navigation path.
u Tap the name of the method that you wish to edit.
The control panel highlights the selected method in green.
u Tap the action [Genera l] .
The control panel shows the action [Genera l] .
u Tap the setting [Gas ty pe ].
The control panel shows a dialog box with an alphanumeric input box.
u Enter the gas type.
u Tap the function [Save] on the function bar.
The setting is saved.
The dialog box closes.
7.5.5 Setting the shelf loading temperature
Navigation path
➔ Method
u Navigate to the [Method ] menu via the navigation path.
u Tap the name of the method that you wish to edit.
The control panel highlights the selected method in green.
u Tap the action [Genera l] .
The control panel shows the action [Genera l] .
u Tap the action Shelf l oa d temp.
The control panel shows a dialog box with a numeric input box.
u Enter the value in the numeric input box.
u Tap the function [Save] on the function bar.
The setting is saved.
The dialog box closes.
7.5.6 Setting the steps of a method
The Pro control panel can save up to 30 steps for each method.
NOTE
The settings for the action Steps affect a single step in each case.
Navigation path
➔ Method
u Navigate to the [Method ] menu via the navigation path.
u Tap the name of the method that you wish to edit.
The control panel highlights the selected method in green.
Operation Manual LyovaporTM L-200 / L-200 Pro 63/96
Page 64
7 | Operating Pro control panel BÜCHI Labortechnik AG
u Tap the action [Steps] .
The control panel shows the action Steps.
The following settings are available for each step:
Setting Option Meaning
[Step p ha se] Primary drying/Sec-
Sets the type of step phase.
ondary drying
[Durati on ] Enter value Sets the duration of the step.
[Drying s helf temperatur e]
Enter value Sets the temperature of the
heatable shelves for the duration of the step in minutes.
[Pressu re range] Regulated/Minimum Regulated: the settings for pres-
sure and pressure limits are applied.
Minimum: the maximum vacuum
is applied to reach the lowest
possible pressure.
[Pressu re ] Enter value Sets a target level for the regu-
lated pressure.
[Pressu re limit] Enter value Absolute value for divergence
from the set pressure before the
sample protection function is activated.
[Pressu re duration ] Enter value Sets the period of time that the
pressure is allowed to exceed
the pressure limit before the
sample protection function is activated.
Editing a step
u Use the function [Right] or [L eft] on the function bar to navigate to the step that
you wish to edit.
u Using the navigation control, navigate to the setting that you wish to change.
u Tap the function [Edit] on the function bar.
u Edit the setting as required.
u Tap the function [Save] on the function bar.
The setting is changed.
Adding a step
u Use the function [Right] or [L eft] on the function bar to navigate to the position at
which you wish to add a step after the position.
u Tap the function [New] on the function bar.
The new step is created.
Deleting a step
u Use the function [Right] or [L eft] on the function bar to navigate to the step that
you wish to delete.
u Tap the function [Delete ] on the function bar.
u Select [OK] to confirm the action in response to the confirmation question.
The step is deleted.
64/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 65
BÜCHI Labortechnik AG Operating Pro control panel | 7
7.5.7 Setting the phases of a method
NOTE
The settings in the Phase view affect all steps of a phase.
Navigation path
➔ Method
u Navigate to the [Method ] menu via the navigation path.
u Tap the name of the method that you wish to edit.
The control panel highlights the selected method in green.
u Tap the action [Phase] .
The control panel shows the Phase view.
The following phases of a method are available:
Phase Setting Option Meaning
[Primar y
drying]
[Pressu re
action]
[Temp. ac tion]
[Safety t emperatur e]
[Sample p rotection t ime]
[End po in t
definit io n]
None/Sample
protection/
Message
None: no action is carried out.
Sample protection: if the pressure is
too high, heating of the shelves is
paused.
Message: if the pressure is too high,
the control panel displays a message.
None/Sample
protection/
Message
None: no action is carried out.
Sample protection: if the temperature is too high, heating of the
shelves is paused.
Message: if the temperature is too
high, the control panel displays a
message.
Entry of value Maximum divergence from the set
collapse temperature before the
sample protection function is activated.
Entry of value Duration of sample protection status
in minutes.
More settings See Chapter7.7 "Setting end point
definitions", page67
Operation Manual LyovaporTM L-200 / L-200 Pro 65/96
Page 66
7 | Operating Pro control panel BÜCHI Labortechnik AG
Phase Setting Option Meaning
[Secondary
drying]
[Pressu re
action]
None/Sample
protection/
Message
None: no action is carried out.
Sample protection: if the pressure is
too high, heating of the shelves is
paused.
Message: if the pressure is too high,
the control panel displays a message.
[Temp. ac tion]
None/Sample
protection/
Message
None: no action is carried out.
Sample protection: if the temperature is too high, heating of the
shelves is paused.
Message: if the temperature is too
high, the control panel displays a
message.
[Safety t emperatur e]
Entry of value Maximum divergence from the set
collapse temperature before the
sample protection function is activated.
[Sample p ro-
Entry of value Duration of sample protection status.
tection t ime]
[Stoppe ring]
[End po in t
definit io n]
[Pressu re
range]
More settings See Chapter7.7 "Setting end point
definitions", page67
Regulated/Minimum
Regulated: the settings for pressure
and pressure limits are applied.
Minimum: the lowest possible vacuum pressure is applied.
[Pressu re ] Entry of value Sets a target value for the regulated
pressure.
[Mode] None/Manual None: no action is carried out.
Manual: sealing is performed manually.
[Hold] [Pressu re
range]
Regulated/Minimum
Regulated: the settings for pressure
are applied.
Minimum: the lowest possible vacuum pressure is applied.
[Pressu re ] Entry of value Sets a level for the regulated pres-
sure.
[Shelf te mperatur e]
Entry of value Specifies a temperature for the
shelves.
Editing the settings for a phase
u Tap the phase that you wish to edit.
The control panel highlights the selected phase in green.
u Tap the setting that you wish to edit.
u Edit the setting as required.
u Tap the function [Save] on the function bar.
The setting is changed.
66/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 67
BÜCHI Labortechnik AG Operating Pro control panel | 7
7.6 Deleting a method
Navigation path
➔ Method
u Navigate to the [Method ] menu via the navigation path.
u Tap the name of the method that you wish to edit.
The control panel highlights the selected method in green.
u Tap the function [Delete ] on the function bar.
u Select [Confir m] to confirm the action in response to the confirmation question.
The method is deleted.
7.7 Setting end point definitions
The end of a phase can be automatically set for each preparation by defining an end
point.
The end point can be defined by means of the temperature difference test or the pressure difference test.
7.7.1 Pressure difference test
The pressure difference test establishes the difference between the readings from
two pressure sensors in the drying chamber. If the difference between the two sensor
readings is below a threshold, the freeze-drying phase can be ended.
Navigation path
➔ Method
Precondition:
R The pressure sensor PPG010 has been installed. See Chapter5.3.5 "Assembling
pressure sensor PPG010 (optional accessory)", page27.
R A capacitive pressure sensor (Inficon Porter CDG020D) is connected.
u Place the alternative pressure sensor in the drying chamber.
u Navigate to the [Method ] menu via the navigation path.
u Tap the name of the method that you wish to edit.
The control panel highlights the selected method in green.
u Tap the action [Phase] .
The control panel shows the action Phase.
u Tap the setting [End po in t defin it io n].
The control panel shows the setting End point definition.
u Tap [Pressu re differ en ce test].
The control panel shows the pressure difference test.
The following settings are available:
Setting Option Explanation
[Pressu re
differe nc e
Yes/No Switches the pressure differ-
ence test on or off.
test]
[Start ti me] Entry of value Sets the time from which the
pressure difference test is to be
performed. The figure relates to
the time before completion of
the primary drying phase.
Operation Manual LyovaporTM L-200 / L-200 Pro 67/96
Page 68
7 | Operating Pro control panel BÜCHI Labortechnik AG
Setting Option Explanation
[Pressu re
differe nc e
limit]
Entry of value Specifies the difference between
the two sensor readings below
which the end point is reached.
[Durati on ] Entry of value Specifies the length of time for
which the pressure difference
test is to be carried out.
[Contin ue ] Yes/No Yes: the method switches to the
next phase.
No: the phase is ended when
the set levels are reached.
[Messag e] Yes/No The control panel shows or does
not show a message as soon as
the pressure difference test is
passed.
7.7.2 Temperature difference test
NOTE
The temperature test is successfully completed if all drying shelves are below the
threshold.
The samples on a drying shelf have different drying times. Take account of the different drying times in the [Durati on ] setting.
The temperature difference test establishes the difference between the readings from
temperature sensor for the heatable shelf and the temperature sensor in the sample.
If the difference between the two sensor readings is below a threshold, the freezedrying phase can be ended.
Navigation path
➔ Method
Precondition:
R The heatable shelves are fitted in the rack. See Chapter5.5.7 "Fitting heatable
shelves", page39.
R The optional temperature sensor has been installed. See Chapter5.5.7 "Fitting
heatable shelves", page39.
u Place the optional temperature sensor in the sample.
u Navigate to the [Method ] menu via the navigation path.
u Tap the name of the method that you wish to edit.
The control panel highlights the selected method in green.
u Tap the action [Phase] .
The control panel shows the action Phase.
u Tap the setting [End po in t defin it io n].
The control panel shows the setting End point definition.
u Tap [Temper at ure dif fe re nce tes t] .
The control panel shows the temperature difference test.
The following settings are available:
68/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 69
BÜCHI Labortechnik AG Operating Pro control panel | 7
Setting Option Explanation
[Temper ature di ff er-
Yes/No Switches the temperature differ-
ence test on or off.
ence te st ]
[Start ti me] Enter setting Sets the time from which the
temperature difference test is to
be performed. The value relates
to the time before completion of
the primary drying phase.
[Temper ature di ff erence li mi t]
Enter setting Specifies the difference between
the two sensor readings below
which the end point is reached.
[Durati on ] Enter setting The period of time during which
the difference is not to be exceeded. If the threshold is not
exceeded for the full period of
time, the temperature difference
test is passed.
[Contin ue ] Yes/No Yes: the method switches to the
next phase.
No: the phase is ended when
the set levels are reached.
[Messag e] Yes/No The control panel shows or does
not show a message as soon as
the temperature difference test
is passed.
7.8 Performing freeze-drying using a method [Pro control panel]
7.8.1 Preparing the instrument
Time
required:
NOTE
The conditioning phase can be skipped by tapping [Skip] on the function bar.
Navigation path
➔ Start
u Navigate to the [Start] menu via the navigation path.
u Tap the function [Start co ndition in g] on the function bar.
7.8.2 Selecting a method
Navigation path
➔ Method
approx.
30min
The temperature in the ice condenser decreases to operating temperature.
The vacuum pump is brought up to operating temperature.
After completion of the conditioning phase, the status bar shows the status Un-
load / Load.
Operation Manual LyovaporTM L-200 / L-200 Pro 69/96
Page 70
7 | Operating Pro control panel BÜCHI Labortechnik AG
u Navigate to the [Method ] menu via the navigation path.
u Tap the function [Method ] on the function bar.
u Tap the method that you wish to use.
u Tap the function [Activa te ] on the function bar.
The status bar shows the method activated.
7.8.3 Starting freeze-drying
CAUTION
Risk of skin burns from touching parts of the ice condenser after completion of conditioning.
u Wear protective gloves when working on the instrument after the conditioning
phase.
NOTE
The freeze-drying process can be cancelled by tapping the functions [Manual ] and
[Aerate ] on the [ Start] menu.
Navigation path
➔ Start
If a gas is being used
Precondition:
R The instrument has been prepared.
R A method is selected.
u Fit a top-mount drying rack. See Chapter5.5 "Assembling the drying attachments",
page32.
u Load the top-mount drying rack with frozen samples.
u Navigate to the [Start] menu via the navigation path.
u Tap the function [Start] on the function bar.
u Make sure that the specified gas is being used.
u Answer YES to the confirmation question.
The freeze-drying process starts.
The control panel shows the [Start] menu with a black background.
The system carries out the selected method.
If a gas is not being used
Precondition:
R The instrument has been prepared.
R A method is selected.
u Fit a top-mount drying rack. See Chapter5.5 "Assembling the drying attachments",
page32.
u Load the top-mount drying rack with frozen samples.
u Navigate to the [Start] menu via the navigation path.
u Tap the function [Start] on the function bar.
The freeze-drying process starts.
The control panel shows the [Start] menu with a black background.
The system carries out the selected method.
70/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 71
BÜCHI Labortechnik AG Operating Pro control panel | 7
7.8.4 Ending freeze-drying
Navigation path
➔ Start
Precondition:
R The status bar is showing the status Hold.
u Navigate to the [Start] menu via the navigation path.
u Tap the function [Aerate ] on the function bar.
u Answer YES to the confirmation question.
The system is vented.
The status bar shows the status Aerating.
u Wait until the status bar shows the status Unload / Load.
u Remove the dried preparation from the top-mount drying rack.
7.8.5 Shutting down the instrument
Time
40min
required:
IMPORTANT
Do not use force to remove the ice from the ice condenser.
Navigation path
➔ Start
Precondition:
R The freeze-drying process has ended.
u Position the condensate drain hose so that the condensate can be drained off.
See Chapter5.3.9 "Preparing the condensate drain hose", page31
u Navigate to the [Start] menu via the navigation path.
u Tap the function [Shut d ow n] on the function bar.
The instrument shuts down.
The status bar shows the remaining time and the status Shutting down.
After the instrument has shut down, the status bar shows the remaining time and
the status Defrosting.
7.9 Performing freeze-drying manually [Pro control panel]
7.9.1 Preparing the instrument
Time
required:
NOTE
The conditioning phase can be skipped by tapping [Skip] on the function bar.
Operation Manual LyovaporTM L-200 / L-200 Pro 71/96
approx.
30min
Page 72
7 | Operating Pro control panel BÜCHI Labortechnik AG
Navigation path
➔ Start
u Navigate to the [Start] menu via the navigation path.
u Tap the function [Start co ndition in g] on the function bar.
The temperature in the ice condenser decreases to operating temperature.
The vacuum pump is brought up to operating temperature.
After completion of the conditioning phase, the status bar shows the status Un-
load / Load.
7.9.2 Starting freeze-drying
CAUTION
Risk of skin burns from touching parts of the ice condenser after completion of conditioning.
u Wear protective gloves when working on the instrument after the conditioning
phase.
Navigation path
➔ Start
Precondition:
R The instrument is prepared.
u Fit a top-mount drying rack. See Chapter5.5 "Assembling the drying attachments",
page32.
u Load the top-mount drying rack with frozen preparations.
u Navigate to the [Start] menu via the navigation path.
u Tap the function [Manual ] on the function bar.
u Enter the required settings for the process parameters.
u Tap the function [Start] on the function bar.
The freeze-drying process starts.
The background colour of the [Start] menu changes from white to black.
The status bar shows a clock counting up and the status Manual Drying.
The system evacuates to the set pressure.
7.9.3 Editing parameters while the process is running
Navigation path
➔ Start
Precondition:
R The process has been started.
u Navigate to the [Start] menu via the navigation path.
u Using the navigation control, navigate to the parameter that you wish to change.
u Tap the function Edit on the function bar.
The control panel shows a dialog box with a numeric input box.
The control panel highlights the selected parameter in white.
u Enter the value in the numeric input box.
72/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 73
BÜCHI Labortechnik AG Operating Pro control panel | 7
u Tap the function [Save] on the function bar.
The setting is saved.
The dialog box closes.
7.9.4 Ending freeze-drying
Navigation path
➔ Start
Precondition:
R The sample is dry.
u Navigate to the [Start] menu via the navigation path.
u Tap the function [Aerate ] on the function bar.
u Answer YES to the confirmation question.
The system is vented.
The status bar shows the status Aerating.
u As soon as the status bar shows the status Unload / Load, remove the dried sam-
ple from the drying rack.
7.9.5 Shutting down the instrument
Time
40min
required:
IMPORTANT
Do not use force to remove the ice from the ice condenser.
Navigation path
➔ Start
Precondition:
R The freeze-drying process has ended.
u Position the condensate drain hose so that the condensate can be drained off.
See Chapter5.3.9 "Preparing the condensate drain hose", page31
u Navigate to the [Start] menu via the navigation path.
u Tap the function [Shut d ow n] on the function bar.
The instrument shuts down.
The status bar shows the remaining time and the status Shutting down.
After the instrument has shut down, the status bar shows the remaining time and
the status Defrosting.
Operation Manual LyovaporTM L-200 / L-200 Pro 73/96
Page 74
8 | Mobile connection BÜCHI Labortechnik AG
LAN
BÜCHI
Cloud
8 Mobile connection
8.1 Setting up BUCHI Connect Solution
The BUCHI Connect Solution is an IT solution for mobile monitoring of processes.
The BUCHI Connect Solution allows processes to be tracked and analysed from a
mobile device while in progress.
Notifications keep the user informed of the status of the instrument.
Similar to the display on the control panel, the BUCHI Monitor app shows the current
settings and actual readings. Depending on the control unit, the BUCHI Monitor app
shows either the alphanumeric data only or the data and progression graph (control
panel Pro) process.
Setting up the BUCHI Connect Solution requires the following steps:
u Connect the instrument to the local network (LAN), see Chapter8.3 "Connecting
the instrument to the LAN", page75.
u Assign dynamic IP addresses (DHCP), see Chapter8.5 "Assigning a dynamic IP
u Enable the control panel for the BUCHI Cloud, see Chapter8.6 "Enabling the con-
address", page76.
trol panel on the BUCHI Cloud", page76.
u Enable ports on the Internet gateway, see .
u Install the BUCHI Monitor app, see Chapter8.7 "Downloading the BUCHI Monitor
app", page76.
u Connect the instrument to the BUCHI Monitor app.
u Activate notifications, see Chapter8.12 "Enabling notifications", page80.
74/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 75
BÜCHI Labortechnik AG Mobile connection | 8
1
8.2 Handling data
The instrument sends the following data to the server via the LAN interface:
Serial number and system name of the control panel
Notifications that have been shown on the mobile device.
The following current process parameters with timestamp:
◦ Process phase and step: actual reading
◦ Condenser temperature: actual reading
◦ Condenser pressure: actual reading and specified setting
◦ Drying chamber pressure: actual reading and specified setting
◦ Drying shelf temperature: actual reading and specified setting
◦ Product temperature: actual reading
◦ Events: phase transition
The process data is regularly deleted and not used for other purposes.
8.3 Connecting the instrument to the LAN
Fig.37: Connection
1 LAN port
u Plug the network cable into the port marked LAN (1).
NOTE
Do not unplug the LAN cable while the device is connected to the BUCHI Connect
Solution.
8.4 Requirements for local network settings
u The following port has to be enabled in the firewall on the internet gateway:
Port 443 (HTTPS) open for TCP
u In order to use the BUCHI Cloud a DNS server must be configured on the inter-
face unit.
NOTE
If there is no DNS server available, the BUCHI Cloud connection must be configured
by entering the IP address.
NOTE
If there is no DHCP server available, the IP address, gateway subnet mask and DNS
server can be configured manually on the interface unit.
Operation Manual LyovaporTM L-200 / L-200 Pro 75/96
Page 76
8 | Mobile connection BÜCHI Labortechnik AG
8.5 Assigning a dynamic IP address
To use the BUCHI Monitor app, enable DHCP on the control panel.
Navigation path
➔ Configuration ➔ Settings ➔ Network➔ DHCP
u Navigate to the action [DHCP] via the navigation path.
u Select the option [Yes].
5 The IP address will now be dynamically assigned.
8.6 Enabling the control panel on the BUCHI Cloud
To use the BUCHI Monitor app, enable access to the BUCHI Cloud on the control
panel.
Navigation path
➔ Configuration ➔ Settings ➔ Network➔ BUCHI Cloud
u Navigate to the action [BUCHI Cl oud] via the navigation path.
u Select the option [Yes].
The instrument is connected to the BUCHI Cloud.
8.7 Downloading the BUCHI Monitor app
Precondition:
R Access to an app store.
R System requirements, see details in app store.
u Start the mobile device.
u Install the BUCHI Monitor app.
u Start the BUCHI Monitor app.
76/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 77
BÜCHI Labortechnik AG Mobile connection | 8
4
35
2
1
8.8 Layout of BUCHI Monitor app
Fig.38: BUCHI Monitor app layout
1 List 2 Settings
3 Messages 4 Content area
5 Details of current instrument and sta-
tus
8.9 Connecting the instrument and app using a QR code
Precondition:
R The BUCHI Monitor app is installed.
u Switch on the instrument.
8.9.1 Generating a QR code
To connect the BUCHI Monitor app to the instrument, generate a QR code on the instrument control panel.
Navigation path
➔ Configuration ➔ Settings ➔ Mobile connection QR code
u Navigate to the action [Mobile c onnecti on Q R code] via the navigation path.
Operation Manual LyovaporTM L-200 / L-200 Pro 77/96
Page 78
8 | Mobile connection BÜCHI Labortechnik AG
5 The control panel shows a QR code.
8.9.2 Scanning the QR code
Fig.39: Capturing the system in the BUCHI Monitor app
Precondition:
R The control panel shows the instrument's QR code.
u Start the BUCHI Monitor app on the mobile device.
u Tap the symbol [List].
The display shows a list of instruments that are connected to the BUCHI Monitor
app.
u Tap the [(+)] sign in the top left corner.
u Tap the option [Scan].
The mobile device switches to camera mode.
u Scan the QR code shown on the control panel.
u Tap [OK] to confirm.
78/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 79
BÜCHI Labortechnik AG Mobile connection | 8
5 The instrument is connected to the BUCHI Monitor app.
NOTE
The system name displayed is taken from the control panel.
8.10 Connecting the instrument and app using a password
Precondition:
R The BUCHI Monitor app is installed.
u Switch on the instrument.
8.10.1 Generating a password
To connect the BUCHI Monitor app to the instrument, generate a password on the instrument control panel.
Navigation path
➔ Configuration ➔ Settings ➔ Mobile connection password
u Navigate to the action [Mobile c onnecti on p assword ] via the navigation path.
The control panel shows the instrument's password.
8.10.2 Entering the password
Fig.40: Capturing the system in the BUCHI Monitor app
Precondition:
R The instrument password is available.
u Start the BUCHI Monitor app on the mobile device.
u Tap the symbol [List].
The display shows a list of instruments that are connected to the BUCHI Monitor
app.
Operation Manual LyovaporTM L-200 / L-200 Pro 79/96
Page 80
8 | Mobile connection BÜCHI Labortechnik AG
1
u Tap the [(+)] sign in the top left corner.
u Tap the option [Manual e ntry].
u Enter the password.
u Tap [Confir m] .
The password entered is applied.
u Tap [OK] to confirm.
5 The instrument is connected to the BUCHI Monitor app.
NOTE
The system name displayed is taken from the control panel.
8.11 Removing the instrument from the app
u Start the BUCHI Monitor app on the mobile device.
u Tap the symbol [List].
The display shows a list of instruments that are connected to the BUCHI Monitor
app.
u Tap the instrument that you wish to remove.
u Tap the Remove symbol in the top right corner.
u Answer the confirmation question.
The instrument is removed from the BUCHI Monitor app.
8.12 Enabling notifications
The BUCHI Monitor app offers a series of notifications that can be sent automatically
to the mobile device while a process is running. The notifications inform the user of
the current status of the process.
Fig.41: Possible settings on the BUCHI Monitor app
1 Name of the active instrument
u Start the BUCHI Monitor app.
u Tap the symbol [Settin gs ].
u Tap the instrument for which you wish to enable notifications.
The display shows a dialog box listing the notification types available.
80/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 81
BÜCHI Labortechnik AG Mobile connection | 8
3
2
1
Fig.42: Dialog box showing notification types
1 Name of the active instrument 2 Check-box
3 Possible notifications
u Select the desired notifications by tapping the relevant check-boxes (2).
Notifications are enabled.
u Tap [OK] to save the settings.
5 The display shows the [Settin gs ] screen.
8.13 Remotely retrieving process data
The data for the process currently running can be retrieved on the BUCHI Monitor
app.
Precondition:
R The BUCHI Monitor app is connected to the instrument.
u Start the BUCHI Monitor app and select the required instrument.
The BUCHI Monitor app home screen is displayed showing a summary of the
available process parameters.
Operation Manual LyovaporTM L-200 / L-200 Pro 81/96
Page 82
9 | Cleaning and servicing BÜCHI Labortechnik AG
9 Cleaning and servicing
NOTE
Users may only carry out the servicing and cleaning operations described in this section.
Any servicing and repair work which involves opening up the casing may only be carried out by BUCHI service technicians.
9.1 Regular maintenance work
Component Action Frequency
Vacuum pump u Carry out maintenance according to
manufacturer's instructions. See relevant documentation.
Top-mount drying
racks
u Wipe down the top-mount drying
racks with a damp cloth.
u If heavily soiled, use ethanol or a mild
detergent.
O-ring, dia. 300
mm
u Wipe down the 300 mm O-rings with
a damp cloth.
u Check for scratches and other dam-
age.
u Replace the 300 mm O-ring if it is
damaged.
u Grease with vacuum grease if neces-
sary.
u Replace the 300 mm O-ring. Annually
Seals
ISO-KF 16
Seals
ISO-KF 25
u Wipe down the seals with a damp
cloth.
u Check for scratches and other dam-
age.
u Replace seals if they are damaged.
Vacuum tubing u Wipe down the vacuum tube with a
damp cloth.
u Check for scratches and other dam-
age.
u Replace the vacuum tube if it is dam-
aged.
Ice condenser u Rinse out with clean water.
u If heavily soiled, use ethanol or a mild
detergent.
Casing u Wipe down the casing with a damp
cloth.
u If heavily soiled, use ethanol or a mild
detergent.
Warning symbols u Check that the warning symbols on
the instrument are legible.
u If they are dirty, clean them.
Heat exchanger u Remove dust and foreign objects
from the ventilation slots using compressed air or a vacuum cleaner.
See manufacturer's
instructions
Daily
Daily
Annually
Annually
Daily
Weekly
Weekly
Monthly
82/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 83
BÜCHI Labortechnik AG Cleaning and servicing | 9
Component Action Frequency
View u Wipe down the display with a damp
Monthly
cloth.
Operation Manual LyovaporTM L-200 / L-200 Pro 83/96
Page 84
9 | Cleaning and servicing BÜCHI Labortechnik AG
9.2 Performing a leak test
The leak test checks the vacuum system for possible leaks.
Time
45min
required:
NOTE
The leak test can be aborted by tapping [Stop] on the function bar.
Navigation path
➜ Configuration ➜ Servicing ➜ Leak test
Precondition:
R A top-mount drying rack is fitted.
u Navigate to the action [Leak t es t] via the navigation path.
u On the Ice Condenser line, enter a required setting for the vacuum.
u On the Volume line, enter the actual volume of the system. The volume of the sys-
tem is calculated from the volume of the ice condenser and the top-mount drying
rack.
u Tap the function [Start] on the function bar.
The leak test starts.
The status bar is showing the status Running.
5 After completion of the leak test, the [Leak t es t] line shows whether the leak test
has been passed or not.
5 The leak test is passed if the measured leakage rate is less than the pre-set rate
of 10.10mbar*L/h.
Troubleshooting after failed leak test
Possible cause Action
Top-mount drying rack not correctly fitted Fit the top-mount drying rack correctly.
300mm dia. O-rings dirty Wipe down the 300mm O-rings with a
300mm dia. O-rings damaged Inspect 300mm O-rings and replace as
KF clamps not closed Close the KF clamps.
KF seals dirty Wipe down the KF seals with a damp
KF seals damaged Inspect KF seals and replace as neces-
Pump oil dirty Service according to manufacturer's in-
9.3 Performing a vacuum test
The vacuum test checks the performance capacity of the vacuum system.
Time
required:
max. 10min
damp cloth.
necessary.
cloth.
sary.
structions.
84/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 85
BÜCHI Labortechnik AG Cleaning and servicing | 9
Navigation path
➜ Configuration ➜ Servicing ➜ Vacuum test
Precondition:
R Conditioning of the instrument has been completed.
R A top-mount drying rack is fitted.
R The top-mount drying rack does not contain a sample.
u Navigate to the action [Vacuum T est] via the navigation path.
u Specify a required setting for the vacuum to be achieved.
u Specify a required time within which the vacuum is to be reached.
u Tap the function [Start] on the function bar.
The vacuum test starts.
The status bar shows the status Vacuum Test.
If the vacuum pressure is not below 500mbar after 30s, the vacuum test automati-
cally aborts.
5 After completion of the vacuum test, the [Vacuum t est] line shows whether the
vacuum test has been passed or not.
Troubleshooting after failed vacuum test
Possible cause Action
Top-mount drying rack not correctly fitted Fit the top-mount drying rack correctly.
300mm dia. O-rings dirty Wipe down the 300mm O-rings with a
damp cloth.
300mm dia. O-rings damaged Inspect 300mm O-rings and replace as
necessary.
KF clamps not closed Close the KF clamps.
KF seals dirty Wipe down the KF seals with a damp
cloth.
KF seals damaged Inspect KF seals and replace as neces-
sary.
The pump connected is not delivering
sufficient performance
Carry out vacuum test with a different
vacuum pump.
Operation Manual LyovaporTM L-200 / L-200 Pro 85/96
Page 86
10 | Help with faults BÜCHI Labortechnik AG
10 Help with faults
10.1 Troubleshooting
Problem Possible cause Action
Compressor fails to
start or switches off
Cooling temperature is not achieved
10.2 Faults, possible causes and remedies
Fault Possible cause Remedy
Instrument does
not work
Main valve (option)
or vacuum pump
switches over frequently
Main valve (option)
does not switch
over
Vacuum is not
achieved
No power supply to compressor
u Check the power supply
and switch on the device.
Compressor overheated u Allow the compressor to
cool down.
u Check ambient conditions.
Circuit-breaker has tripped u Reset circuit of L-200.
Wrong ambient conditions Adjust ambient conditions.
See Chapter5.1 "Installation
site", page21
Too much ice in the ice con-
Defrost the ice condenser.
denser
Instrument is not connected to
the power supply.
u Make sure that the power
supply is connected and
switched on.
Vacuum system is leaking. u Carry out a leak test (see
Chapter9.2 "Performing a
leak test", page84).
u If necessary, replace tub-
ing and/or seals.
Main valve fitted wrong way
round.
u Fit main valve correct way
round (arrow pointing towards vacuum pump).
Main valve lead not plugged
in.
u Make sure that the electri-
cal lead of the main valve
is plugged into the correct
socket on the rear of the
instrument.
Vacuum system is leaking. u Carry out a leak test (see
Chapter9.2 "Performing a
leak test", page84).
u Carry out a vacuum test
(see Chapter9.3 "Performing a vacuum test",
page84).
u If necessary, replace tub-
ing and/or seals.
Vacuum pump is too weak. u Use a vacuum pump with a
capacity of at least 5m3/h.
u Carry out maintenance
work according to the vacuum pump manufacturer's
documentation.
86/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 87
BÜCHI Labortechnik AG Help with faults | 10
Fault Possible cause Remedy
Instrument is not
vented
Main valve is incorrectly connected.
u Connect main valve cor-
rectly (see Chapter5.3.4
"Assembling the main
valve (optional accessory)", page25).
Operation Manual LyovaporTM L-200 / L-200 Pro 87/96
Page 88
11 | Taking out of service and disposal BÜCHI Labortechnik AG
11 Taking out of service and disposal
11.1 Disposal
The operator is responsible for proper disposal of the Lyovapor™.
CAUTION
Potential environmental hazard
The device uses refrigerant R507. This refrigerant is toxic and must not be allowed to
enter the soil or groundwater.
u Dispose of the appliance properly, if necessary using a professional disposal ser-
vice.
u When disposing of equipment observe the local regulations and statutory require-
ments regarding waste disposal.
11.2 Returning the instrument
Before returning the instrument, contact the BÜCHI Labortechnik AG Service Department.
https://www.buchi.com/contact
88/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 89
BÜCHI Labortechnik AG Appendix | 12
12 Appendix
12.1 Spare parts and accessories
Use only genuine BUCHI consumables and spare parts in order to ensure correct,
safe and reliable operation of the system.
NOTE
Any modifications of spare parts or assemblies are only allowed with the prior written
permission of BUCHI.
12.1.1 Top-mount drying rack accessories
Description Order no. Image
Drying chamber tube, PMMA, L 368 mm,
D 300 mm
11063278
Drying chamber tube, PMMA, L 480 mm,
D 300 mm
Top cover, PMMA, D 300 mm 11062912
Top cover manifold, PMMA, with 12
valves, D 300 mm
Top cover stoppering D 300 mm 11064314
Rack for 4 heatable shelves 11065102
11065093
11065595
Operation Manual LyovaporTM L-200 / L-200 Pro 89/96
Page 90
12 | Appendix BÜCHI Labortechnik AG
Description Order no. Image
Rack for 6 heatable shelves 11065103
Heatable shelf, aluminum coated, with
11064095
connection cable
Sample tray, stainless steel, D 220 mm 11061439
Ferrule, Ø 218 mm 11065816
Drying rack manifold, stainless steel,
11063664
with 12 valves
Drip pan, for manifold 11065720
Support for rack, stainless steel 11063789
Baseplate, stainless steel, for manifold
11064953
rack
90/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 91
BÜCHI Labortechnik AG Appendix | 12
Description Order no. Image
Baseplate, PMMA, for manifold rack 11065733
Suction nipple 11065819
Ampoule adapter for manifold
with 19 ampoule connections and cap
adapter
Flask beaker for manifold 100 mL
with cap adapter and integrated filter
Flask beaker for manifold 200 mL
with cap adapter and integrated filter
Flask beaker for manifold 600 mL
with cap adapter and integrated filter
Flask beaker for manifold 1200 mL
with cap adapter and integrated filter
11065725
11066140
11066141
11066142
11066143
12.1.2 Accessories
Description Order no. Image
Main valve 11062223
Operation Manual LyovaporTM L-200 / L-200 Pro 91/96
Page 92
12 | Appendix BÜCHI Labortechnik AG
Description Order no. Image
Pressure sensor PPG010 11062228
Pressure sensor Inficon PSG 550 11062229
Pressure sensor Inficon CDG 020 D 11062230
Pressure regulation valve 11064725
Aeration valve 11064724
PT1000 sample temperature sensor 11064031
12.1.3 Further accessories
Description Order no. Image
Trolley L-200, stainless steel coated 11063692
92/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 93
BÜCHI Labortechnik AG Appendix | 12
12.1.4 Spare parts
Description Order no. Image
User interface 11063580
User interface Pro 11063581
O-Ring Ø 300 mm 11065367
Vacuum hose, KF 25, L 1000 mm 11066031
Vacuum clamp KF 16 11064939
Vacuum clamp KF 25 11063662
Vacuum clamp, KF 40 11063663
Vacuum sealing KF 16 11063455
Operation Manual LyovaporTM L-200 / L-200 Pro 93/96
Page 94
12 | Appendix BÜCHI Labortechnik AG
Description Order no. Image
Vacuum sealing KF 25 11063457
Vacuum sealing KF 40 11063659
Vacuum flange adapter, stainless steel,
11064870
KF 16 to KF 25
Blind flange KF 16 11064902
Blind flange KF 25 11063660
Blind flange KF 40 11063661
94/96 Operation Manual Lyovapor
TM
L-200 / L-200 Pro
Page 95
Page 96
Quality in your hands
BUCHI Affiliates:
We are represented by more than 100 distribution partners worldwide.
Find your local representative at: www.buchi.com
BUCHI Support Centers:
Europe
Switzerland/Austria
BÜCHI Labortechnik AG
CH – 9230 Flawil
T +41 71 394 63 63
F +41 71 394 64 64
buchi@buchi.com
www.buchi.com
Benelux
BÜCHI Labortechnik GmbH
Branch O ffice Benelu x
NL – 3342 GT Hendrik-Ido-Ambacht
T +31 78 684 94 29
F +31 78 684 94 30
benelux@buchi.com
www.buchi.com/bx-en
France
BUCHI Sarl
FR – 94656 Run gis Cedex
T +33 1 56 70 62 50
F +33 1 46 86 00 31
france@buchi.com
www.buchi.com/fr-fr
Germany
BÜCHI Labortechnik GmbH
DE – 45127 Essen
T +800 414 0 414 0 (Toll Free)
T +49 201 747 49 0
F +49 201 747 49 20
deutschland@buchi.com
www.buchi.com/de-de
Italy
BUCHI Italia s.r.l.
IT – 20010 Cornaredo (MI)
T +39 02 824 50 11
F +39 02 575 12 855
italia@buchi.com
www.buchi.com/it-it
Russia
BUCHI Russia/CIS
Russia 127287 Moscow
T +7 495 36 36 495
russia@buchi.com
www.buchi.com/ru-ru
United Kingdom
BUCHI UK Ltd.
GB – Oldha m OL9 9QL
T +44 161 633 1000
F +44 161 633 1007
uk@buchi.com
www.buchi.com/gb-en
Germany
BÜCHI NIR-Online
DE – 69190 Walldor f
T +49 6227 73 26 60
F +49 6227 73 26 70
nir-online@buchi.com
www.nir-online.de
China
BUCHI China
CN – 200052 Shanghai
T +86 21 6280 3366
F +86 21 5230 8821
china@buchi.com
www.buchi.com/cn-zh
India
BUCHI India Private Ltd.
IN – Mumbai 400 055
T +91 22 667 75400
F +91 22 667 18986
india@buchi.com
www.buchi.com/in-en
Indonesia
PT. BUCHI Indonesia
ID – Tangerang 15321
T +62 21 537 62 16
F +62 21 537 62 17
indonesia@buchi.com
www.buchi.com/id-in
Japan
Nihon BUCHI K.K.
JP – Tokyo 110-0008
T +81 3 3821 4777
F +81 3 3821 4555
nihon@buchi.com
www.buchi.com/jp-ja
Korea
BUCHI Korea Inc.
KR – Seoul 153-782
T +82 2 6718 7500
F +82 2 6718 7599
korea@buchi.com
www.buchi.com/kr-ko
Malaysia
BUCHI Malaysia Sdn. Bhd.
MY – 47301 Petaling Jaya,
Selangor
T +60 3 7832 0310
F +60 3 7832 0309
malaysia@buchi.com
www.buchi.com/my-en
Singapore
BUCHI Singapore P te. Ltd.
SG – Singapore 609919
T +65 6565 1175
F +65 6566 7047
singapore@buchi.com
www.buchi.com/sg-en
Thailand
BUCHI (Thailand) Ltd.
TH – Bangkok 10600
T +66 2 862 08 51
F +66 2 862 08 54
thailand@buchi.com
www.buchi.com/th-th
Asia
America
Brazil
BUCHI Brasil Ltda.
BR – Valinhos SP 13271-200
T +55 19 3849 1201
F +55 19 3849 2907
brasil@buchi.com
www.buchi.com/br-pt
USA/Canada
BUCHI Corporation
US – New Castle, DE 19720
T +1 877 692 8244 (Toll Free)
T +1 302 652 3000
F +1 302 652 8777
us-sales@buchi.com
www.buchi.com/us-en
South East Asia
BUCHI (Thailand) Ltd.
TH-Bangkok 10600
T +66 2 862 08 51
F +66 2 862 08 54
bacc@buchi.com
www.buchi.com/th-th
Middle East
BÜCHI Labortechnik AG
UAE – Dubai
T +971 4 313 2860
F +971 4 313 2861
middleeast@buchi.com
www.buchi.com
Latin America
BUCHI Latinoamérica Ltda.
BR – Valinhos SP 13271-200
T +55 19 3849 1201
F +55 19 3849 2907
latinoamerica@buchi.com
www.buchi.com/es-es
Loading...