Bio-Rad GS-800 Calibrated Densitometer User Manual
Model GS-800 ™
Calibrated Imaging
4000188 Rev. B Copyright 2002 Bio-Rad Laboratories Inc.
Densitometer
User Guide
For Catalog Numbers
170-7980 GS-800 Densitometer, PC
For Technical Service
Call Your Local Bio-Rad Office or
In the U.S. Call 1-800-4BIORAD
(1-800-424-6723)
WWW.BIO-RAD.COM
Warranty Statement
Bio-Rad Model GS-800 Calibrated Imaging Densitometer
This warranty may vary outside of the United States. Please contact your local Bio-Rad
office for the exact terms of your warranty.
Bio-Rad Laboratories warrants to the customer that the Model GS-800 Calibrated Imaging
Densitometer (Catalog Number 170-7980) will be free from defects in material and
workmanship, and will meet all performance specifications for the period of one year from
the date of shipment. This warranty covers all parts and labor.
In the event that the instrument must be returned for repair under warranty, the
instrument must be packed for return in the original packaging.
Bio-Rad shall not be liable for any incidental, special or consequential loss, damage, or
expense directly or indirectly arising from the use of the Model GS-800 Calibrated Imaging
Densitometer. Bio-Rad makes no warranty whatsoever in regard to products or parts
furnished by third parties, such being subject to the warranty of their respective
manufacturers. Service under this warranty shall be requested by contacting the
customer’s nearest Bio-Rad office.
This warranty does not extend to any instruments or parts thereof that have been subject
to misuse, neglect or accident, or that have been modified by anyone other than Bio-Rad or
Bio-Rad's authorized agent, or that have been used in violation of Bio-Rad instructions.
For any inquiry or request for repair service, contact Bio-Rad Laboratories. Inform BioRad of the model and serial number of your instrument.
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Table of Contents
SECTION 1 GENERAL INFORMATION .................................................................................................................4
1.1 INTRODUCTION ................................................................................................................................................... 4
1.2 INSTALLATION QUALIFICATION AND OPERATIONAL QUALIFICATION ( IQ/OQ )................................. 4
1.3 SAFETY................................................................................................................................................................... 5
SECTION 2 SETTING UP............................................................................................................................................. 6
2.1 CHECKING THE CONTENTS ...............................................................................................................................6
2.2 UNPACKING THE CONTENTS ............................................................................................................................ 6
2.3 UNLOCKING THE DENSITOMETER AND THE TRANSPARENCY MODULE.................................................. 7
2.4 LOCKING THE DENSITOMETER AND THE TRANSPARENCY MODULE ....................................................... 8
2.5 TAKING A CLOSER LOOK ...................................................................................................................................8
SECTION 3 INSTALLATION.................................................................................................................................... 10
3.1 ABOUT USB DEVICES ........................................................................................................................................10
3.2 INSTALLATION WITH A PC .............................................................................................................................. 10
3.3 CONNECT THE DENSITOMETER TO THE COMPUTER ..................................................................................10
3.3 TESTING THE DENSITOMETER......................................................................................................................... 12
SECTION 4 OPERATION ..........................................................................................................................................13
4.1 OVERVIEW OF OPERATIONAL COMPONENTS............................................................................................... 13
4.2 START-UP ............................................................................................................................................................. 15
4.3 REFLECTIVE SCANNING ...................................................................................................................................15
4.4 TRANSMITTANCE SCANNING .........................................................................................................................16
SECTION 5 MAINTENANCE ...................................................................................................................................17
5.1 CLEANING THE IMAGE WINDOW GLASS ...................................................................................................... 17
5.2 CLEANING THE CABINET EXTERIOR .............................................................................................................. 17
SECTION 6 TROUBLESHOOTING.........................................................................................................................18
6.1 TROUBLESHOOTING..........................................................................................................................................18
6.2 TECHNICAL SERVICE ........................................................................................................................................ 20
SECTION 7 : SUPPORT DOCUMENTATIONS................................................................................................... 21
7.1 TECHNICAL SPECIFICATIONS ............................................................................................................................. 21
7.2 DECLARATION OF CONFORMITY:................................................................................................................... 21
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Section 1 General Information
1.1 Introduction
The Model GS-800 Calibrated Imaging Densitometer is a high performance, calibrated
imaging densitometer that converts transparent and opaque electrophoretic samples into
digital data. These data are analyzed with Quantity One® software operating in Microsoft
Windows® computer systems. For a step-by-step guide to scanning and analyzing images,
please refer to your QuantityOne software user manual.
The main features of the Model GS-800 Calibrated Imaging Densitometer include:
• Adjustable resolution from 36.3 microns to 127.0 microns;
• Reflectance and transmittance
• Scanning area of 29 cm by 40 cm
• Sampling rate of up to 700 dots per inch (dpi).
• Variable wavelength filter architecture for improved color discrimination
• Analog to digital conversion at full 12-bit accuracy
• Calibrated transmission tablet to ensure accurate OD readings
• Reflective gray scale tablet to ensure reproducible reflectance values
• Supported by Quantity One software, which provides versatile image display,
optimization, and quantitation features
• USB interface
1.2 Installation Qualification and Operational Qualification (IQ/OQ)
The calibration of the Model GS-800 Calibrated Imaging Densitometer can be validated by
following the GS-800 Calibrated Densitometer Installation Qualification and Operational
Qualification protocols. These protocols are available as an accessory to the GS-800
Calibrated Imaging Densitometer (Catalog number 170-7956) these straightforward and
simple to follow IQ/OQ protocols include instructions for the installation of the hardware
and software, and instructions for the verification of the reflectance and transmittance
calibration functions.
Following proper installation, a linear dynamic range of 3.0 OD for the
Transmissive scanning and 2.0 OD for Reflectance scanning can be confirmed with
greater than 95% confidence. For additional details, contact your local Bio-Rad
Representative.
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1.3 Safety
The Model GS-800 Calibrated Imaging Densitometer system uses high voltage and high
current and should be operated with care at all times. To avoid shock, set up the GS-800
Densitometer in a dry area. Immediately wipe up any spilled solutions.
• Turn off the Densitometer, and then disconnect the power plug when you want to
clean the Densitometer case or glass plate, or when the Densitometer needs service or
repair.
• Place the Densitometer on a level surface.
• To ensure proper ventilation, allow a minimum of 15 cm free space around each side of
the Densitometer.
• Do not leave photographs, gels, or film on the glass plate for excessive periods of time.
The heat from the light source in the Densitometer may cause them to deteriorate.
• Do not operate the Densitometer when the environmental temperature falls below 5° C
or rises above 40° C.
• Do not operate the Densitometer when the environmental humidity falls below 20% or
rises above 85%.
1.4 Regulatory Compliance*
Declaration of Compliance
The party responsible for product compliance
Corporate Name: UMAX Technologies, Inc.
Address: Techville, Inc.
11343 N. Central Expwy
Telephone No.:
Dallas, TX 75243 USA
Tel.: (214) 739-7033
*See UMAX PowerLook 2100XL Operation Manual
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Section 2 Setting Up
2.1 Checking the Contents
Your Model GS-800 Calibrated Imaging Densitometer system should arrive complete with
one of each of the following:
• GS-800 Calibrated Imaging Densitometer
• GS-800 Calibrated Imaging Densitometer User Guide
• Quantity One™ Image Analysis Software
• UMAX PowerLook 2100XL Operation Manual
• USB Cable
• Power Cord
• Warranty Card (please complete and return to Bio-Rad)
• MagicScan CD and manual
These components may arrive in several boxes. If your system is missing any of these
items, immediately contact your local Bio-Rad office for a prompt replacement. Please
retain all packaging material. Additional charges will be assessed if packaging is not
available for instrument warranty service shipping.
Caution: Use care when unpacking your equipment. The equipment is delicate and
damage can occur if it is dropped or otherwise mistreated.
2.2 Unpacking the Contents
Unpacking the Model GS-800 Calibrated Imaging Densitometer shipping container:
Warning: The Model GS-800 Calibrated Imaging Densitometer weighs approximately
46.17 lbs. (20.8 kg). To avoid personal injury, two people may be needed to lift the
Densitometer out of the shipping container. Lifting the unit just by the lid may cause
damage to the instrument
1. Carefully lift the Model GS-800 Calibrated Imaging Densitometer out of the shipping
carton and place it on a stable, dry, flat surface. The chassis of the Model GS-800
Calibrated Imaging Densitometer attempts to conform to any uneven surface. This
may result in a poor-quality scan.
2. Remove the plastic wrapping and the packing materials from the Densitometer.
3. The Model GS-800 Calibrated Imaging Densitometer should be located close to the
computer system to which it will be connected. Select a flat, dry surface that
provides adequate ventilation on all sides to prevent overheating.
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4. The Model GS-800 Calibrated Imaging Densitometer can operate with 100V AC to
240V AC. Check the power cord to insure that it is suitable for your area.
Caution: The power cord plug provided has a third grounding pin. This plug fits in a
grounding-type outlet only. This is a safety feature. If you are unable to plug the power
cord into a wall outlet, locate another outlet that can accommodate the plug or contact
your electrician to change the outlet. Do not change the plug.
2.3 Unlocking the Densitometer and the Transparency Module
The optical assembly of the Densitometer’s transparency module (located in the lid) is held
in place during shipment by a carriage lock (Figure 2.1) on the underside of the
transparency module. The carriage lock must be unlocked before the instrument will
work properly. Additionally, if the carriage lock is not unlocked prior to use, the optical
system may be damaged while scanning. Insert a coin into the Carriage Lock. Turn it
until the mark points align with the unlocked mark.
Note: Leave the locking screw in place so that it can be re-locked if you have to move the
Densitometer over long distances.
Carriage
Lock
Fig. 2.1 Front view of Densitometer. Unlock the carriage lock by turning with a coin.
Warning: Always lower the transparency module slowly and release it only when it lies
flat on the body of the Densitometer.
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