LEICA CM1950 User Guide

Leica CM1950
THE Disinfecting Clinical Cryostats
Protect
THE cryostats for high quality sectioning, user safety and efficient workflow
The Leica CM1950 platform is the latest innovation in a long line of distinguished cryostats manufactured by Leica Microsystems. Leica designed and developed the new family of cryostats based upon users’ feedback and their requirements for high quality sections, user safety, and efficient laboratory workflow.
High Quality Sectioning
High precision microtome with stepper motor object feed
Motorized sectioning (optional)
New stable specimen clamp system
New flat specimen discs for high specimen stability
New rapid-freezing shelf design
New effective object cooling system (optional)
User Safety
UVC disinfection
AgProtect™ antimicrobial nanosilver surface coating
New disposable blade holder CE
Debris-free, frost-free enclosed microtome assembly
Leica’s Section Waste Removal System (optional)
Spacious cabinet with rounded edges inside and out
Efficient Workflow
UVC disinfection at any time and temperature
Organized work space inside and out
Frost-free, encapsulated microtome assembly
Leica’s Section Waste Removal System with easily-accessible,
concealed filter system (optional)
Easily recognizable control symbols
Visible operating parameters at all times
The brightl cabinet is allow effici ple specim
Learn quickly and work confi­dently using the externally loca­ted, self-explanatory controls with easily recognizable sym­bols.
For an extra measure of safety, the inside of the instrument features an ozone-free UVC disinfection system that is certified to be effective against most bacteria, virus, and fun­gi, even at cold temperatures.
Increased safety for the user and others in the immediate work area: Leica’s AgProtect™ antimicrobial nanosilver surface coating deters the propagation of infectious agents on the outside of the instrument.
To protect the laboratory environment from contamination, a multi-filter system (including HEPA filter) removes particulates and cleans the air exhausted from the optional Section Waste Removal System
Liquid condensate collected in an eas ble waste container
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Store tools, glass slides, stai­ning containers, etc. in a recessed area on top of the cryostat to have these items immediately at hand.
For extra ease of use and con­sistent sectioning of all speci­men types, an optional sectio­ning motor drive is available.
Leica Design by Werner Hölbl
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THE cryostats
for high quality sectioning
Obtain high quality sections through:
NEW: CryoZone™ blade holder and anti-roll guide cooling
Maintaining the ideal object temperature for specific specimens
Great stability of the microtome and blade holder system
Extreme accuracy of the stepper motor object feed
Consistent, motor-driven cutting stroke (optional)
Vacuum-assisted sectioning aid (optional)
High precision microtome with exact stepper motor object feed.
CryoZone™ – the cool way to improve section quality
The CryoZone™ system controls a zone of uniformly cool air in the critical areas of the cryochamber. This cool air circulates around the specimen, knife and anti-roll guide to create the optimal conditions for con­sistent, high-quality sectioning.
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Efficient specimen loading is achieved via single lever operation that provides maximum clamping force indepen­dent of individual user strength.Direct contact cooling through the (optional) actively cooled object head facili­tates rapid changes of specimen temperatures to provide the best conditions for sectioning various specimen types.
High specimen stability is achieved by adherence to deeply grooved specimen discs. Specimens freeze quickly because the pre-cooled discs feature a large back surface that fully contacts the freezing shelf with integrated Peltier element.
Superior sectioning of routine, hard, and/or large samples is achieved using a choice of knife/blade holders as well as the new dove tail mounting system that provides increased sta­bility and extended working distance. The new CE holder for high and low profile disposable blades evenly distributes clamping pressure across the entire length of the blade, which provides vibration-free sectioning.
The new CN and CNZ knife holders are available for steel or tungsten carbide knives (optional accessories).
The optional vacuum sectioning aid achieves time-sav­ing section preparation and reduces section curling.
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