Leica M205 C, M125, M125 IND, M205 A, M165 C User Manual

Leica M205 A, M205 C,

Living up to Life

M165 C & M125

Experience another dimension in stereomicroscopy with the new, high performance
stereomicroscopes from Leica.

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Ever since their introduction by Horatio S. Greenough, stereomicroscopes have

worked according to the optical principles based primarily on Ernst Abbe’s

research. For over a century, ingenious optics designers and engineers have

worked to push magnification, resolution and image fidelity to the limit permitted

by optics. In doing so, they have always been constrained by the interrelation bet-

ween three factors: the higher a microscope’s resolution, the lower the available

working distance. If one increases the distance of the optical axes, the three-

dimensional image seen by the observer becomes distorted a cube then becomes

a tower, a flat surface curves towards the observer.

Limits are made to be broken.

LeicaM205 A and M205 C are the first stereomicroscopes in the world that can

offer a 20.5 : 1 zoom. This accomplishment, however, was not enough for Leica’s

engineers. With the new FusionOptics™, they have succeeded in taking yet

another step beyond previous limits. Besides the greater magnification, they have

also increased the resolution to 1050lp/mm, which corresponds to a resolved struc-

ture size of 476nm.

Of course, this performance increase is reflected in your daily work: Set up your

specimens on the microscope table with comfortable freedom of movement and

discover details that were previously unrevealed, even in stereomicroscopy.

A Step Towards Infinity

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The human brain is a fascinating piece of work. Using the data it receives from

both eyes, it calculates a three-dimensional image of our environment in an unceas -

ing stream. What is truly remarkable, however, is the brain’s ability to gauge

situations with lightning speed based on the information it receives, and to react to

such situations appropriately.

Brain jogging with the Leica M205 A and M205 C

The new Leica M205 A and M205 C stereomicroscopes with FusionOptics™ rely on

the unsurpassed adaptability of the brain. The microscope assigns a different task

to each of the two beam paths: the right channel contains an image with very high

resolution, while the left channel provides very high depth of field. The brain then

automatically gathers the best information from both sources and uses it to com-

pose one image with very high richness of detail and depth of field.

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Juggling Increases Brain Size

Previous studies assumed that humans build brain mass during childhood, develop

neurological networking through training in adolescence, can at best maintain this

complexity during midlife, and will unavoidably experience diminished mental per-

formance with increasing age.

Now, a study led by Dr. Arne May * of the University of Regensburg has shown

that certain regions of the adult brain have the ability to build brain matter through

training. In a group of laypersons who practiced juggling over a three-month

period, structural changes in the cerebral cortex were identified after the training

period. Astonishingly, the new brain matter formed primarily in the two areas that

are responsible for vision and touch. Obviously, the difficulty in juggling lies in

visually capturing and analyzing the balls’ movements.

Leica FusionOptics™ takes advantage of the flexibility of our brains, and as an

added benefit improves mental performance capability.

The areas marked in yellow are the regions in which

new brain matter was shown to have been created.

Courtesy of Dr. Arne May (University Clinic Hamburg)

* Dr. Arne May, “Juggling boosts adult brain power”,
http://www.uni-protokolle.de/nachrichten/id/28051/

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