Leica CM1510 S User Manual

Leica CM1510 S

The Economic Cryostat

for Routine Histology

Characteristics of the Leica CM1510 S

• Splash-protected high precision microtome

• Specimen orientation

• Motorized coarse feed in two different speeds

• Cryochamber temperature 0 °C to -30 °C

• Automated and manual cryochamber defrost cycle

• Actively cooled quick freezing shelf, lowest

possible temperature -45 °C, with manual defrost

on demand

• Illuminated cryochamber

• Heated sliding window, removable

• Compact dimensions

• Cryocabinet on rollers

The new Leica CM1510 S is a cryostat which reliably meets all

demands in routine cryomicrotomy and excels by outstanding

economic efficiency: a very attractively priced instrument which

leaves no desires open in its class; compact dimensions –

especially advantageous in laboratories where space is limited;

high specimen throughput for rapid and efficient performance,

and a proven track record of reliability. And of course – just as

any other Leica product – the Leica CM1510 S offers exemplary

safety standards and is capable of fulfilling even the most

exacting operator requirements for excellent ergonomics. ......

Compact Dimensions,

High Specimen Throughput,

Excellent Cost-Performance Ratio

Comfortable: The handwheel

To ensure protection against

injury when changing specimens

and/or knives, the smooth-run-

ning handwheel is lockable in the

upper position.

Powerful: The quick-freezing shelf

The actively cooled quick-freezing shelf

(-45 °C) with heat extractor allows extre-

mely fast specimen freezing. A manual

defrost cycle can be activated whenever

necessary.

The CN knife holder is equipped with a

high-quality glass anti-roll plate, as is

the CE knife holder. The edges of the

glass insert are manufactured using a

special procedure to make them more

durable and fracture-resistant. All four

edges of the insert can be used.

Knife holder CN* for standard microtome knives

Fast: Motorized coarse feed

The motorized coarse feed en-

ables rapid trimming. Two diffrent

speed settings in each direction

for improved efficiency.

The Leica CM1510 S is the best value cryostat available

for Mohs surgery. Mohs micrographic surgery is a means

of excising skin cancers in layers, rapidly freezing and

cutting thin sections

of the frozen tissue

samples, and exami-

ning the sections

microscopically until

a layer is reached

that is free of tumor.

Functional: The CE* knife holder

The lateral displacement feature of the

CE knife holder for disposable blades

allows the use of the whole blade

length. The integrated glass anti-roll

guide is automatically carried along

when displacing the knife holder. The

CE knife holder is ideally suited for

cutting serial sections of up to 3 µm in

thickness.

Spacious: The stainless steel cryochamber

The perfectly illuminated and insulated cryochamber is easily accessible through a heated

sliding window. Ample space is provided for convenient specimen handling.

* Optional accessories

Rapid: The specimen orientation

The easy-to-use specimen orientation

system produces top quality sections –

even of critical samples such as skin – in a

minimum of time.

Precise and fast cryo-

embedding with the

new Cryoembedding

System by Dr. Stephen

Peters.*

Leica CM1510 S – Technical specification

Chamber defrosting: automatic hot gas defrosting cycle;

duration: 8 min. Starting time

freely programmable;

manual defrost cycle on demandg

Temperature

of quick freeze shelf: max. -45 °C

at a cyrochamber temperature of -30 °C
Quick freeze
shelf defrosting: manual defrost cycle on demand

Cryocabinet:

Dimensions (W x H x D): 680 x 1175 x 680 mm
Weight (incl. microtome): 120 kg

Section thickness selection: 1 to 60 µm:

in 1-µm steps from 1 to 10 µm
in 2-µm steps from 10 to 20 µm
in 5-µm steps from 20 to 60 µm

Maximum specimen size: 55 mm Ø
Total horizontal specimen feed: 25 mm
Total vertical specimen stroke: 59 mm
Specimen orientation: with 0-positioning,

8° x/y, part of standard delivery
Trimming: via motorized coarse feed
Motorized coarse feed: 2 speed settings:

rapid: 0.65 mm/sec

slow: 0.3 mm/sec

Refrigerating capacity:

Temperature selection range: 0 °C to -30 °C
Time required to refrigerate to -30°C: approx. 3 h

at 22 °C ambient temperature

procedures – certified under DIN EN ISO 9001 – ensure highest
quality and reliability.
A wide range of accessories available on request.
Technical specification subject to change without prior notice.

As confirmed by the successful c-CSA-us certification, the Leica
CM1510 S has been designed and manufactured in compliance
with UL, CSA and IEC requirements.
State-of-the-art development, manufacturing and quality control

©Leica Microsystems Nussloch GmbH, Heidelberger Str. 17-19, D-69226 Nussloch, Tel. [phone], Fax [phone]

Order No. B708 201121/05

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Heidelberger Strasse 17-19

D-69226 Nussloch

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