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Offer to Provide Source Code of Certain Software
This product contains copyrighted software that is licensed under the General Public License (“GPL”),
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Licenses. Such software in this product is distributed without any warranty to the extent permitted by the
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Where the applicable license entitles you to the source code of such software and/or other additional data,
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ii
Contents
Safety information ....................................................................................................... v
About this guide ......................................................................................................... vi
X99-S specifications summary ............................................................................... viii
Package contents ..................................................................................................... xiv
Installation tools and components .......................................................................... xv
Chapter 1: Product Introduction
1.1 Special features..........................................................................................1-1
ASUS contact information ...................................................................................... A-4
iv
Safety information
Electrical safety
• To prevent electrical shock hazard, disconnect the power cable from the electrical outlet
before relocating the system.
• When adding or removing devices to or from the system, ensure that the power cables
for the devices are unplugged before the signal cables are connected. If possible,
disconnect all power cables from the existing system before you add a device.
• Before connecting or removing signal cables from the motherboard, ensure that all
power cables are unplugged.
• Seek professional assistance before using an adapter or extension cord. These devices
could interrupt the grounding circuit.
• Ensure that your power supply is set to the correct voltage in your area. If you are not
sure about the voltage of the electrical outlet you are using, contact your local power
company.
• If the power supply is broken, do not try to x it by yourself. Contact a qualied service
technician or your retailer.
Operation safety
• Before installing the motherboard and adding devices on it, carefully read all the manuals
that came with the package.
• Before using the product, ensure all cables are correctly connected and the power
cables are not damaged. If you detect any damage, contact your dealer immediately.
• To avoid short circuits, keep paper clips, screws, and staples away from connectors,
slots, sockets and circuitry.
• Avoid dust, humidity, and temperature extremes. Do not place the product in any area
where it may become wet.
• Place the product on a stable surface.
• If you encounter technical problems with the product, contact a qualied service
technician or your retailer.
v
About this guide
This user guide contains the information you need when installing and conguring the
motherboard.
How this guide is organized
This guide contains the following parts:
1. Chapter 1: Product introduction
This chapter describes the features of the motherboard and the new technology it
supports. It includes description of the switches, jumpers, and connectors on the
motherboard.
2. Chapter 2: Basic installation
This chapter lists the hardware setup procedures that you have to perform when
installing system components.
3. Chapter 3: BIOS setup
This chapter tells how to change system settings through the BIOS Setup menus.
Detailed descriptions of the BIOS parameters are also provided.
Where to find more information
Refer to the following sources for additional information and for product and software
updates.
1. ASUS website
The ASUS website (www.asus.com) provides updated information on ASUS hardware
and software products.
2. Optional documentation
Your product package may include optional documentation, such as warranty yers,
that may have been added by your dealer. These documents are not part of the
standard package.
vi
Conventions used in this guide
To ensure that you perform certain tasks properly, take note of the following symbols used
throughout this manual.
DANGER/WARNING: Information to prevent injury to yourself when trying to
complete a task.
CAUTION: Information to prevent damage to the components when trying to
complete a task
IMPORTANT: Instructions that you MUST follow to complete a task.
NOTE: Tips and additional information to help you complete a task.
Typography
Bold text
Italics
<Key>Keys enclosed in the less-than and greater-than sign
<Key1> + <Key2> + <Key3>If you must press two or more keys simultaneously, the key
Indicates a menu or an item to select.
Used to emphasize a word or a phrase.
means that you must press the enclosed key.
Example: <Enter> means that you must press the Enter or
Return key.
names are linked with a plus sign (+).
vii
X99-S specifications summary
LGA2011-v3 socket for Intel® Core™ i7 processors
CPU
Chipset
Memory
Expansion slots
Multi-GPU support
Storage
Supports 22nm CPU
Supports Intel® Turbo Boost Technology 2.0*
*The support of this feature depends on the CPU types.
*Hyper DIMM support is subject to the physical characteristics of individual
CPUs. Please refer to Memory QVL (Qualified Vendors List) for details.
40-LANE CPU
5 x PCI Express 3.0/2.0 x16 slots* (single at x16, dual at x16/x16, triple
at x16/x16/x8**, quad at x8/x8/x16/x8, or quintuple at x8/x8/x8/x8/x8
mode)
1 x PCI Express 2.0 x4 slot*** (compatible with PCIe x1 and x4 devices)
28-LANE CPU
3 x PCI Express 3.0/2.0 x16 slots (single at x16, dual at x16/x8, triple at
x8/x8/x8 mode)
2 x PCI Express 2.0 x16 slots (max. at x1 mode, compatible with PCIe
x1 devices)
1 x PCI Express 2.0 x4 slot*** (compatible with PCIe x1 and x4 devices)
*The PCIe x16_5 shares bandwidth with M.2 x4.
** The PCIe 3.0/2.0 configuration is default set at x8/x8/x8. Adjust the
bandwidth of PCIe x16_5 slot in BIOS.
***The PCIe x4_1, USB3_E12 and SATAEXPRESS_E1 connectors share the
same bandwidth. The SATAEXPRESS_E1 slot is disabled when there is a
device installed on PCIe x4_1 slot. Set this option to X2 mode or x4 mode
when the installed PCIe device is higher than x4 interface.
- Supports jack-detection, multi-streaming and front panel jackretasking (MIC)
- Optical S/PDIF out ports at rear I/O
Intel® X99 Express Chipset - supports ASUS USB 3.0
Boost
- 4 x USB 3.0/2.0 ports at mid-board for front panel support
- 6 x USB 2.0/1.1 ports (4 ports at mid-board, 4 ports at rear
panel)
ASMedia® USB 3.0 controllers - support ASUS USB 3.0
Boost
- 8 x USB 3.0/2.0 ports at rear panel (blue)
(continued on the next page)
ix
X99-S specifications summary
Flagship Performance
5-Way Optimization by Dual Intelligent Processors 5
- Whole system optimization with a single click! 5-Way
Optimization tuning key perfectly consolidates TPU, EPU,
DIGI+ Power Control, Fan Xpert 3, and Turbo APP together,
providing better CPU performance, efcient power saving,
precise digital power control, whole system cooling, and even
tailor your own app usages.
DIGI+ Power Control
CPU Power
- Industry leading digital 8-phase power design
- ASUS CPU power utility
DRAM Power
- Industry leading digital 4-phase DRAM power design
- ASUS DRAM power utility
TPU
- Auto Tuning, TPU, GPU Boost, 2-level TPU switch
EPU
- EPU, EPU switch
ASUS Fan Xpert3
- Featuring Fan Auto Tuning function and multiple thermistors
ASUS Exclusive
Features
selection for optimized system cooling control.
Turbo App
- Featuring automatic system performance tuning, network
priority, and audio scene conguration for selected
applications.
UEFI BIOS
- Most advanced options with fast response time
M.2 and SATA Express onboard
- The latest transfer technology with up to 32 Gb/s data transfer
speeds for M.2
- The ultra-fast transfer technology with up to 10 Gb/s data
transfer speeds for SATA Express
Special Memory O.C. Design
- Superb memory O.C. capability under full load by minimizing
the coupling noise and signal reection effect
Thunderbolt Ready (Optional)
- Blistering-fast 20 Gb/s data transfer upgrades with
ThunderboltEX II series
Powerful Home Server
ASUS HomeCloud Server
Media Streamer
- Pipe music or movies from your PC to a smart TV
- Media Streamer app for portable smartphone/tablet,
supporting iOS7 and Android 4.0 systems
(continued on the next page)
x
X99-S specifications summary
Gamers and Professionals
Turbo APP
- Perform each application with tailored performance, network
priority, and audio conguration for your needs
Turbo LAN
- Experience smooth online gaming with lower pings and less
lags
Crystal Sound 2
- Feel the sound power with different usage scenarios
Steam support
- Compatible with the most fun gaming platform under
Windows® system
ASUS EZ DIY
ASUS Exclusive Features
ASUS Special Features
Push Notice
- Monitor your PC status with smart devices in real time
USB BIOS Flashback
- with USB BIOS Flashback Wizard for EZ BIOS download
scheduling
UEFI BIOS EZ Mode
- featuring friendly graphics user interface
- ASUS O.C. Tuner
- ASUS CrashFree BIOS 3
- ASUS EZ Flash 2
Q-Design
- ASUS Q-Code
- ASUS Q-Shield
- ASUS Q-LED (CPU, DRAM, VGA, Boot Device LED)
- ASUS Q-Slot
- ASUS Q-DIMM
- ASUS Q-Connector
ASUS 5X Protection:
- ASUS DIGI+VRM - 8 phase digital power design
- ASUS Enhanced DRAM Overcurrent Protection - Short
circuit damage prevention
- ASUS ESD Guards - Enhanced ESD protection
- ASUS High-Quality 5K-Hour Solid Capacitors - 2.5x long
lifespan with excellent durability
- ASUS Stainless Steel Back I/O - 3x more durable corrosionresistant coating
USB 3.0 Boost
USB Charger+
Ai Charger+
Disk Unlocker
AI Suite 3
MemOK!
EZ XMP
(continued on the next page)
xi
X99-S specifications summary
ASUS Quiet Thermal
Solution
ASUS Exclusive
Overclocking Features
Rear Panel I/O Ports
Internal I/O connectors
Quiet Thermal Design
- ASUS Fan Xpert 3
- ASUS Fanless Design: Heat-pipe solution with an aesthetic
streamline IO cover
Precision Tweaker 2
- vCore: Adjustable CPU Core voltage at 0.001 V increment
- iGPU: Adjustable CPU Graphics voltage at 0.001 V increment
- vCCIO: Adjustable Analog and Digital I/O voltage at 0.001 V
increment
- vCCIN: Adjustable CPU Input voltage at 0.01 V increment
- vCCSA: Adjustable CPU System Agent voltage at 0.001 V
increment
- vDRAM Bus: 110-step Memory voltage control
- vPCH: 176-step Chipset voltage control
SFS (Stepless Frequency Selection)
- BCLK/PCIE frequency tuning from 80 MHz to 300 MHz at 0.1
MHz increment.
Overclocking Protection
- ASUS C.P.R. (CPU Parameter Recall)
1 x BIOS Flashback button
1 x Optical S/PDIF Out port
1 x Intel® LAN (RJ45) port
8 x USB 3.0/2.0 ports (blue)
2 x USB 2.0/1.1 ports (bottom port supports USB BIOS Flashback)
8-channel Audio I/O ports
2 x 19-pin USB 3.0/2.0 connectors support additional 4 USB ports
2 x USB 2.0/1.1 connectors support additional 4 USB ports
1 x M.2 Socket 3 with vertical M Key design, type 2242/2260/2280
storage devices support (PCIe mode only)
2 x SATA Express connectors (gray)
8 x SATA 6 Gb/s connectors (4 x gray, 4 x black)
1 x 4-pin CPU Fan connector for both 3-pin (DC mode) and 4-pin
(PWM mode) CPU coolers control with auto-detection support
1 x 4-pin CPU Optional Fan connector (CPU_OPT)
4 x 4-pin Chassis Fan connectors for 3-pin (DC mode) and 4-pin
(PWM mode) coolers control
1 x Front panel audio connector (AAFP)
1 x S/PDIF out header
1 x 5-pin Thunderbolt header for ThunderboltEX II series support
1 x TPM connector
1 x 24-pin EATX Power connector
1 x 8-pin EATX 12V Power connector
1 x System Panel (Q-Connector)
1 x 5-pin EXT_FAN (Extension Fan) connector
(continued on the next page)
xii
X99-S specifications summary
1 x 3-pin CHASSIS (Chassis intrusion) connector
1 x MemOK! button
1 x Clear CMOS button
1 x EPU switch
1 x TPU switch (with advanced two-stage adjustments)
Internal I/O connectors
BIOS features
Manageability
Support DVD contents
Operating system support
Form factor
Specications are subject to change without notice.
1 x 2-pin Thermal sensor header
1 x 3-pin CPU OverVoltage (OV) header
1 x DirectKey (DRCT) connector
1 x EZ XMP switch
1 x SLI/CFX switch (2/3-Way adjustments)
1 x Power-on switch
1 x Reset switch
128 Mb Flash ROM, UEFI AMI BIOS, PnP, DMI 2.7, WfM 2.0,
SM BIOS 2.7, ACPI 5.0, Multi-language BIOS, ASUS EZ Flash
2, CrashFree BIOS 3, F11 EZ Tuning Wizard, F6 Qfan Control,
F3 My Favorites, Quick Note, Last Modied Log, F12 PrintScreen
function, F3 Shortcut function, and ASUS DRAM SPD (Serial
Presence Detect) memory information
WfM 2.0, DMI 2.7, WOL by PME, PXE
Drivers
ASUS Utilities
EZ Update
Anti-virus software (OEM version)
Windows® 8.1 / Windows® 8 / Windows® 7
ATX form factor: 12 in. x 9.6 in. (30.5 cm x 24.4 cm)
xiii
Package contents
Check your motherboard package for the following items
3 x Serial ATA 6 Gb/s cables
ASUS X99-S motherboard
1 x 2-in-1 ASUS Q-Connector kit*
1 x ASUS Q-Shield
1 x ASUS SLI™ bridge connector
M.2 Bracket
User Manual
xiv
Support DVD
• If any of the above items is damaged or missing, contact your retailer.
• *The Q-Connector is bundled for retailer package only.
• The illustrated items above are for reference only. Actual product specications may
vary with different models.
User Guide
Installation tools and components
Intel® LGA2011-v3 compatible CPU Fan
Intel® LGA2011-v3 CPU
PC chassis
Power supply unit
SATA optical disc drive (optional)
SATA hard disk drive
1 bag of screws
Philips (cross) screwdriver
DIMM
Graphics card
The tools and components in the table above are not included in the motherboard package.
xv
xvi
Chapter 1: Product Introduction
Product introduction
1
1.1 Special features
1.1.1 Product highlights
LGA2011-v3 socket for Intel® Core™ i7 processors
This motherboard supports Intel® Core™ i7 processors in the LGA2011-v3 package. It
provides great graphics and system performance with its GPU, quad-channel DDR4 memory
slots and PCI Express 2.0/3.0 expansion slots.
Intel® X99 Express Chipset
Intel® X99 Express Chipset is a single chipset that supports the LGA2011-v3 socket for Intel
Core™ i7 processors. It utilizes the serial point-to-point links, which increases bandwidth
and enhances the system’s performance. It natively supports up to eight (8) USB 3.0 ports,
fourteen (14) SATA 6 Gb/s ports, and M.2 support for faster data retrieval. It also enables the
iGPU function for Intel® integrated graphics performance.
PCI Express® 3.0
PCI Express® 3.0 (PCIe 3.0) is the PCI Express bus standard that provides twice the
performance and speed of PCIe 2.0. It provides an optimal graphics performance,
unprecedented data speed and seamless transition with its complete backward compatibility
to PCIe 1.0/2.0 devices.
3-WAY/Quad-GPU SLI and 3-WAY CrossFireX™ Support
This motherboad features NVIDIA 3-WAY/Quad SLI and 3-Way AMD CrossreX support that
enables mulit-GPU setup, giving you the full power of the latest graphics technologies. It also
features native support for 4K/UHD (ultra high denition) resolution of up to 4096 x 2160 via
HDMI or DisplayPort, resulting to four times the number of pixels for incredible visual clarity,
detail, and realism.
SATA Express support
SATA Express provides faster data transfer speeds of up to 10 Gb/s, allowing your system to
catch up with the speed of the SSDs. It also features backward compatibility with up to two
SATA drives of the same speed.
®
ASUS X99-S
Chapter 1
1-1
Quad-Channel DDR4 3200 MHz Support
The motherboard supports the quad-channel DDR4 memory that features data transfer rates
of DDR4 3200 MHz to boost the system’s performance, and to meet the higher bandwidth
requirements of 3D graphics, multimedia and Internet applications.
Dual PCIe 3.0 x4 M.2 Support
With an x4 PCI Express 3.0/2.0 bandwidth, the M.2 can support up to 32 Gbit/s of data
tranfer speed. It is a perfect choice for the operating system or application drive, making your
system and its installed apps work in a faster pace.
Complete USB 3.0 integration
This motherboard offers you the strategic USB 3.0 accessibility for both the front and rear
panels, allowing you to experience the convenience of the latest plug and play connectivity
solution at speed up to ten times faster than USB 2.0.
1.1.2 Other special features
DTS Connect
To get the most out of your audio entertainment across all formats and quality levels, DTS
Connect combines two enabling technologies, DTS Neo:PC™ upmixes stereo sources (CDs,
MP3s, WMAs, internet radio) into as many as 7.1 channels of incredible surround sound.
Consumers can connect their PC to a home theater system. DTS Interactive is capable of
performing mult-channel encoding of DTS bitstreams on personal computers, and sending
encoded bitstreams out of a digital audio connection (such as S/PDIF or HDMI) designed to
deliver audio to an external decoder.
DTS UltraPC II
DTS UltraPC II delivers a superior surround sound experience through your system’s
speakers and headphones while monitoring and balancing the loudness level difference
between digital audio formats. It also ehnances the audio settings through augmenting
low and high frequencies of musical tones, restores compressed or re-mastered sounds,
improves bass performance even without a subwoofer, and improves dialogues derived from
DVD or Blu-ray Disc™.
ErP Ready
The motherboard is European Union’s Energy-related Products (ErP) ready, and ErP
requires products to meet certain energy efciency requirement in regards to energy
consumptions. This is in line with ASUS vision of creating environment-friendly and energy-
efcient products through product design and innovation to reduce carbon footprint of the
product and thus mitigate environmental impacts.
Chapter 1
1-2
Chapter 1: Product introduction
1.2 Motherboard overview
1.2.1 Before you proceed
Take note of the following precautions before you install motherboard components or change
any motherboard settings.
• Unplug the power cord from the wall socket before touching any component.
• Before handling components, use a grounded wrist strap or touch a safely grounded
object or a metal object, such as the power supply case, to avoid damaging them due
to static electricity.
• Hold components by the edges to avoid touching the ICs on them.
• Whenever you uninstall any component, place it on a grounded antistatic pad or in the
bag that came with the component.
• Before you install or remove any component, ensure that the ATX power supply is
switched off or the power cord is detached from the power supply. Failure to do so
may cause severe damage to the motherboard, peripherals, or components.
ASUS X99-S
Chapter 1
1-3
1.2.2 Motherboard layout
Chapter 1
1-4
Refer to 1.2.9 Internal connectors and 2.3.1 Rear I/O connection for more information
about rear panel connectors and internal connectors.
Chapter 1: Product introduction
Layout contents
Connectors/Jumpers/Buttons and switches/SlotsPage
1. DDR4 DIMM slots1-7
2. CPU, CPU optional, extension, and chassis fan connectors
(4-pin CPU_FAN, 4-pin CPU_OPT, 5-pin EXT_FAN, 4-pin CHA_FAN1-4 )
3. LGA2011-v3 CPU socket 1-6
4. ATX power connectors (24-pin EATXPWR, 8-pin EATX12V) 1-33
5. MemOK! button1-16
6. M.2 Socket 31-36
7. EPU switch1-18
8. Intel® Serial ATA 6 Gb/s connectors (7-pin SATA6G_12, SATA 6G_34,
SATA 6G_56/SATAEXPRESS_1, SATA 6G_78, SATA6G_910)
9. ASMedia® Serial ATA 6 Gb/s connectors (7-pin SATA6G_E12/
SATAEXPRESS_E1)
10. TPU switch1-17
11. Thunderbolt header (5-pin TB_HEADER)1-36
12. CPU Over Voltage jumper (3-pin CPU_OV) 1-20
13. System panel connector (20-8 pin PANEL) 1-34
14. DirectKey connector (2-pin DRCT)1-35
15. USB 2.0 connectors (10-1 pin USB1112; USB1314)1-31
16. EZ XMP switch 1-20
17. USB 3.0 connectors (20-1 pin USB3_12, USB3_34)1-30
18. SLI/CFX switch 1-19
19. TPM connector (20-1 pin TPM)1-35
20. Clear CMOS button (CLR_CMOS)1-19
21. Q-Code LEDs1-23
22. Reset button1-15
23. Power-on button1-15
24. Front panel audio connector (10-1 pin AAFP)1-29
25. Digital audio connector (4-1 pin SPDIF_OUT)1-29
The motherboard comes with a surface mount LGA2011-v3 socket designed for Intel
i7 processors.
• Ensure that all power cables are unplugged before installing the CPU.
• Upon purchase of the motherboard, ensure that the PnP cap is on the socket and
the socket contacts are not bent. Contact your retailer immediately if the PnP cap
is missing, or if you see any damage to the PnP cap/socket contacts/motherboard
components. ASUS will shoulder the cost of repair only if the damage is shipment/
transit-related.
• Keep the cap after installing the motherboard. ASUS will process Return Merchandise
Authorization (RMA) requests only if the motherboard comes with the cap on the
LGA2011-v3 socket.
• The product warranty does not cover damage to the socket contacts resulting from
incorrect CPU installation/removal, or misplacement/loss/incorrect removal of the PnP
cap.
®
Core™
Chapter 1
1-6
Chapter 1: Product introduction
1.2.4 System memory
The motherboard comes with eight DDR 4 (Double Data Rate 4) Quad Inline Memory
Modules (DIMM) slots.
A DDR4 module is notched differently from a DDR, DDR2, or DDR3 module. DO NOT
install a DDR, DDR2, or DDR3 memory module to the DDR4 slot.
Recommended memory configurations
ASUS X99-S
Chapter 1
1-7
Memory configurations
You may install 2 GB, 4 GB and 8 GB unbuffered and non-ECC DDR4 DIMMs into the DIMM
sockets.
• You may install varying memory sizes in Channel A, Channel B, Channel C, and
Channel D. The system maps the total size of the lower-sized channel for the quad-
channel conguration. Any excess memory from the higher-sized channel is then
mapped for single-channel operation.
• According to Intel® CPU spec, DIMM voltage below 1.65 V is recommended to protect
the CPU.
• Due to the memory address limitation on 32-bit Windows® OS, when you install 4GB
or more memory on the motherboard, the actual usable memory for the OS can be
about 3GB or less. For effective use of memory, we recommend that you do any of the
following:
a) Use a maximum of 3GB system memory if you are using a 32-bit Windows
b) Install a 64-bit Windows® OS when you want to install 4 GB or more on the
motherboard.
c) For more details, refer to the Microsoft® support site at http://support.microsoft.
com/kb/929605/en-us.
• The default memory operation frequency is dependent on its Serial Presence Detect
(SPD), which is the standard way of accessing information from a memory module.
Under the default state, some memory modules for overclocking may operate at a
lower frequency than the vendor-marked value. To operate at the vendor-marked
or at a higher frequency, refer to section 3.5 Ai Tweakermenu for manual memory
frequency adjustment.
• For system stability, use a more efcient memory cooling system to support a full
memory load (8 DIMMs) or overclocking condition.
• Memory modules with memory frequency higher than 2133MHz and their
corresponding timing or the loaded XMP prole is not the JEDEC memory standard.
The stability and compatibility of the memory modules depend on the CPU’s
capabilities and other installed devices.
• Always install the DIMMS with the same CAS Latency. For an optimum compatibility,
we recommend that you install memory modules of the same version or data code
(D/C) from the same vendor. Check with the vendor to get the correct memory
modules.