Leica PICOVITRO FLYER User Manual
Synergies in High
Content Screening
New Picovitro HCS Microwell Slides for
Leica HCS A High Content Screening Automation
The Perfect Match:
Screen 672 Experiments on One Slide!
In High Content Screening (HCS), a large number of experiments have to be imaged and analyzed
efficiently. Picovitro and Leica Microsystems create a joint concept for high content screening of
single cell cultivation and in vitro imaging for medical and life science research applications.
Picovitro HCS Slides:
At the size of a conventional slide, 672 microwells are etched
•
in silica body, optimized for single cell culturing
Optimal for imaging: The extremely plane silica body is bonded
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gluefree to the 0.17 mm glass bottom for optical perfection
Semi-permeable silicone membrane prohibits evaporation,
•
facilitates gas exchange, and avoids contamination
Fully compatible to Leica HCS A screening microscopes
•
with standard inserts
Leica HCS A Imaging Systems:
Highest resolution is achieved by confocal point scanner
•
and widefi eld systems
Highly sensitive: spectral photomultiplier detectors
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and digital cameras
Large objective range from 10x/0.4 to 100x/1.4
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optimized for 0.17 mm glass bottom
High speed 2D, 3D and 4D fully automated image acquisition
•
Leica HCS A Screening Solutions
Run screens fully automated without assistance
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Predefi ned scanning templates for easy Picovitro applications,
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autofocus algorithms and drift compensation
OME image format compatible to image analysis software
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Computer Aided Microscopy (CAM) programming interface
•
for remote system control
+ = 672 x +
2
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