
Leica HCS A
High Content Screening Automation
Technical Documentation

Leica HCS A
High Content Screening Automation
LAS AF MATRIX M3 Software Platform
Amplify the power of your imaging system by HCS A and convert your confocal into a High Content Screening System. Maximum
fl exibility is provided for universal applications and easy automation enables effi cient screening. Computer Aided Microscopy
allows external system control and turns your Leica imaging system into an intelligent microscope.
Leica TCS SP5
Leica HCS A
2
Leica TCS SPE
Leica TCS LSI

Leica HCS A
Product Overview
Imaging automation LAS AF MATRIX Mosaic Advanced 156602501
Remote system control LAS AF MATRIX Mosaic+Multiwell Advanced 156602502
LAS AF MATRIX Mosaic Full Version 156602504
LAS AF MATRIX Multiwell Full Version 156602505
LAS AF MATRIX Full Version w/o CAM 156602511
LAS AF MATRIX Developer Entry 156602512
Accessory Tools LAS AF MATRIX Developer Full w. CAM 156602514
LAS AF MATRIX Single Object Tracking 156602507
Upgrades LAS AF MATRIX Pump2 156602508
LAS AF MATRIX Z-Drift Compensator 156602509
LAS AF MATRIX Advanced Trigger
LAS AF MATRIX Upgrade Mosaic Adv. to Mosaic Full Version 156602515
LAS AF MATRIX Upgrade Developer Entry to Full Version 156602519
Technical Data
Platforms System support1 TCS SP5, TCS SPE, TCS LSI
LAS AF version 2.2.1 or higher
Image acquisition Imaging technologies True confocal point scanner
Export formats Image types TIF, OME.TIF, LIF
Image data OS platform indpendent
Network Protocol TCP/IP
Administration Local system admin
Remote system control Control via network Yes, with CAM
Control interface Computer Aided Microscopy, CAM
Compatible software (examples) Not included in the packages
Programming languages C++, C#, VB
LabVIEW™, MATLAB™
Image programming Adobe Photoshop
Image analysis software ImageJ2 with LOCI plugins
Defi niens® Challenger
MetaMorph®, Leica MM AF
Limitations LAS AF MATRIX M3, version 2.2.1 Hardware excluded: TCS SP5 X, MP, STED, DMI 6000 CFS
Software excluded: TCS SMD FCS, FLIM, FLCS
FRAP, FRET, Electrophysiology
System Requirements
2
156602510
®
®
®
Imaging systems Platform TCS SP5, TCS SPE,TCS LSI
Computing Operating System Windows® XP, SP2
Recommended
Processor speed Mhz 3
Memory GB 4
Hard disc GB 500
Network Yes
Platform Stand Part No. XY-Travel Range
3
Motorized Stages TCS SP5 DM 15 6504 150 100 x 80 mm
DMI 15 6504 141 127 x 83 mm
TCS SPE DM 15 6605 200 72 x 38 mm
DMI 15 6605 201 127 x 83 mm
TCS LSI LSI-Base 15 6905 202 127 x 83 mm
Annotations:
1
Supports technology within the range of the product specifi cation.
2
Supported by TCS SP5 only with additional external hardware.
3
Please note that depending on different well plate formats and platforms the outer wells might not be scanned due to mechancial restrictions. Test is recommended.
Open Microscopy Environment (OME) is a multi-site collaborative effort among academic laboratories and a number of commercial entities that produces open tools to support data
management for biological light microscopy. Designed to interact with existing commercial software, all OME formats and software are free, and all OME source code is available under
GNU public copyleft licenses. OME is developed as a joint project between research-active laboratories at the Dundee, NIA Baltimore and Harvard Medical School and LOCI.
C++ is a programming language standardized by ISO. C# is a programming language developed by Microsoft, Inc. LabVIEW™ is a registered trademark of NI National Instruments Inc.
MATLAB™ is a registered trademark of The MathWorks™, Inc. Adope Photoshop® is a registered trademak of Adobe Systems® Incorporated.
ImageJ is a public domain Java image processing program inspired by National Institutes of Health, NIH. Windows® XP is a registered trademark of the Microsoft® Corporation.
Defi niens® is a registered trademark of Defi niens AG. Meta-Morph® is a registered trademark of MDS Analytical Technologies.
3

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