Taylor-Wharton CXR500 User Manual

Operating Instructions

SAFETY

Before using any cryogenic refrigerator, read
the Handle with Care booklet provided with the
unit. It details safety precautions that must be
understood before using the equipment. If a
replacement booklet is needed, order
publication TW-10 Handle with Care from your
supplier.

Following are a few of the safety precautions
described in the Handle with Care booklet. Please
be sure to read the entire booklet.

Store and use these containers only in well
ventilated areas. In a confined area, nitrogen gas

from these units may cause suffocation by
displacing air needed for breathing. Install a
suitable oxygen monitor.

Do not touch liquid or cold metal surfaces with
your bare skin. The liquid nitrogen refrigerant in

these containers is extremely cold: -196°C (­320°F). Exposure of skin or eyes to liquid, cold
gas or frosted parts could result in a severe
frostbite-like injury. Because of the extremely low
temperature, a face shield and gloves must be
worn when transferring liquid nitrogen and material
into or out of these containers.

Use only the necktube core supplied with this
unit or a listed replacement part. A tight fitting

plug or stopper will cause a pressure increase in
the container that may damage the container
and/or cause personal injury.

Dispose of liquid nitrogen only in areas
specifically designed for that purpose.
Disposal of liquid nitrogen should be done
outdoors in a safe place. Pour the liquid slowly
on gravel or bare earth where it can evaporate
without causing damage.

OPERATION

Important note: Before filling the CXR series
for the first time, record the tare weight and
serial number of each container. Recording the
“as received” tare weight on the container
itself is recommended.

Filling: Adding liquid nitrogen to warm container

may cause splashing and will generate a sufficient
volume of nitrogen gas as cold liquid contacts
warm refrigerator surfaces. Add liquid slowly to
minimize these effects. Be sure there is adequate
ventilation. Keep your head clear of the heavy
volume of vapor that may be produced. It is
extremely cold and could cause personal injury

WARNING
DO NOT OVERFILL. Over-filling may result in
personal injury due to liquid spillage.

With regular usage, moisture can
accumulate in the refrigerator as a result of
lowering a frosted canister back into the
shipping cavity. This moisture will displace
nitrogen in the adsorbent material on the
subsequent filling and effect the overall
holding time.

CAUTION:
When filling the Cryogenic Refrigerator,
avoid liquid nitrogen coming in contact with
the vacuum plug. In order to accomplish this,
the Cryo-Exchange must be removed from
its shipping carton during the “fill” operation.

Remove the unit from its shipping
enclosure. Set the unit on a scale and fill

the refrigerator with liquid nitrogen to about
half way up the necktube. Allow the unit to
stand undisturbed while the liquid is being
adsorbed. About every five minutes, add
liquid to maintain the level half way up the
necktube as the liquid is adsorbed by the
filler material. This procedure can take four
or more cycles. Replace the necktube core
and allow it to “float” on the liquid. Allow the
unit to stand undisturbed for 18 to 24 hours
while the liquid is being adsorbed. After this
point, the quantity of liquid standing in the
central cavity of the refrigerator must be
poured out to prevent spillage during
shipment. To assure a complete fill, the dry
CXR100 weight should increase by
approximately 6.5 lb. (3.0 kg) and the dry
CXR500 weight should increase by
approximately 11.5 lb. (5.2 kg).

The material to be stored in the Cryo­Exchange refrigerator, as well as the
canister or rack, should be pre-cooled before
being placed in the shipper. When the
refrigerator is fully charged, place the pre­cooled canister and lower it into the
necktube. Install the necktube core and cap
to hold the canister in place.

CAUTION:
When the Cryo-Exchange is in use, it must
be kept upright. When properly filled, there is
no concern for liquid refrigerant spills.
However, holding time will be drastically
reduced when the refrigerator is on its side.

Securing contents: The contents of all
models may be secured with a seal or lock
through tabs on the edge of the lid.

ROUTINE CARE AND MAINTENANCE

Do not attempt to fasten any device to the
container. Welding, brazing, or piercing of the
container in any manner will cause
permanent damage.

TW-362

Cryo-Exchange

Vapor Shippers

With Replaceable Adsorbent

Refrigeration depends on the presence of liquid nitrogen refrigerant in
the refrigerator. Be sure to maintain a full charge of refrigerant to
prevent loss of stored materials. Please refer to the “Operations”
section of this document for instructions on the filling procedure. If you
are not able to fully charge the Cryo-Exchange unit by weight, it is
possible that moisture has accumulated in the filler material over time
with normal usage. This accumulation will result in displacement of
refrigerant. Direct dry heat not to exceed 150
dryer or other source) into the refrigerator. The unit is acceptably dry
when the tare weight is within 1 lb. (0.45 kg) of the “as received from
the manufacturer” tare weight. If the tare weight is still not satisfactory,
or contamination is suspected, a new set of adsorbent socks can be
purchased to bring the unit back to factory specifications.

o

F (65o C) (from a hair

REPLACING THE ADSORBENT

FIGURE 1.0

A) On a clean working surface in a well ventilated area and the

CXR at ambient temperature, begin by removing the cap
assembly and canister (items 1 and 2) shown above in figure

1.0.

B) Wearing gloves made from one of the following:

polyethylene/ethylene vinyl alcohol, polyvinyl alcohol, Teflon
or Viton, reach down the necktube and remove the core
(item 3).

C) Reach in and remove one at a time the 7 adsorbent socks

(item 4). Dispose of the used socks properly.

D) Clean the empty CXR (item 5) with an approved disinfectant,

and then dry thoroughly.

E) Replace the Adsorbent socks with TW part number CXR100-

9C30. Place the socks down the necktube standing them

vertically around the perimeter of the CXR.
F) Replace the Core (item 3)
G) Fill the CXR per the procedure found in the operation section

of this manual.

TW-362

TRANSPORTATION

Although these refrigerators are rugged, they can be damaged if
abused or otherwise mishandled. A specially designed hard-shell

shipping container (refer to the parts section for ordering information)
should be used anytime the refrigerator is transported. This container
will help prolong the life of the unit and should be replaced if damaged
during use. When moving or transporting a refrigerator, take every
precaution to prevent sliding, tipping, bumping, or dropping the unit.
Keep the unit upright. Although there is no safety hazard if the
properly filled refrigerator is on its side, the refrigerant consumption is
much greater with the unit in this position and holding time will be
significantly reduced.

RETURNS

Manufacturing defects are covered under the containers limited
warranty. Evidence of mishandling, such as dents on the outer vessel,
or misalignment of the inner vessel, are not manufacturing defects. If
high evaporation rates are apparent under normal operating
conditions, the refrigerator may be losing its vacuum. Sweating and
the formation of frost on the outer casing are indications the
refrigerator may be losing its vacuum. All necessary steps should be
taken to protect the refrigerator’s contents. Please contact your
supplier for information on how to conduct a normal evaporation rate
(NER) test in the field.
If you would like to return goods to Taylor-Wharton for any reason, you
must first obtain a Material Return Authorization (MRA) number for
tracking purposes. Please have a description of your symptoms and
your serial number ready. Contact your supplier or call us at 1-800 TW
TANKS or
e-mail us at [e-mail]

REPLACEMENT PARTS

Description CXR100 CXR500

Handle CXR100-6C12 N/A

Handle, Pin 8631-5000 N/A

Canister CXR100-9C24 Note*

Neckplug Assembly CXR100-9C16 CP70-9C18

Core Sleeve CXR100-9C20 CXR500-9C20

Adsorbent Sock (Set) CXR100-9C30

Decal CXR100-9C25 CXR500-9C25

Hard Shell Shipping Enclosure CX10-8C00 CP19-8C00

Padded Carton Shipping Enclosure 3701-9277 N/A

Note*: Five shelf rack (for TW plastic box)…………RS30-9C40
Blood Bag Rack……………………………………….CP70-9C44

.

CXR100-9C30

(2 Sets)