3M MICROFLUOR II Specifications

Microfluor®II Critical Sterilizing Grade PTFE

Cartridge and Capsule Membrane Filters

Microfluor II PTFE membrane filters offer the ultimate in

microorganism retention for air and gas streams while

providing superior air flow capacity.

CUNO’S Microfluor II filters with flow enhanced

construction allow use of smaller, more economical air

filter assemblies compared to competitive air filters.

Microfluor II filters provide absolute retention based on

liquid bacteria challenge and aerosol bacteriophage

challenge.

Microfluor II filters are available in a wide range of

cartridge and capsule configurations to provide the most

New flow enhanced cartridge and capsule filter construction

provides lower differential pressure than competitive filters

economical solution to air, gas and aggressive liquid

filtration applications.

Cartridge and Capsule Configurations to Meet Any Process Requirement

Microfluor II membrane filters are available in 5 through 40 inch cartridges, 2.5 and 5 inch Mini Cartridges and

2.5, 5, 10, 20 and 30 inch capsules. With the exceptionally high Microfluor II flow rates, smaller and more economical assemblies can provide the same air flow as larger, more costly competitive PTFE filters.

Feature Benefit

Unique flow enhancing layer construction

Liquid validation of B. diminuta retention

Hydrophobic PTFE membrane

21 CFR Materials of Construction, USP Biological Safety Test, Validation Guide and Drug Master File Listing

Higher air flow for fermenter aeration and smaller, more economical vent filter assemblies

Reliable sterilizing performance in wet or dry conditions

Membrane will not become blocked with moisture

Eases validation and regulatory submissions

Microfluor®II Cartridge and Capsule Filter Applications

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Microfluor II filters are optimized for applications requiring sterilization of air, gas, or aggressive solvents and chemicals. The hydrophobic PTFE filter membrane prevents wetting with aqueous liquids or moisture that can block free air flow. Some applications, however, may require filtration of aggressive fluids such as acids or bases. Depending on compatibility, Microfluor II filters can be used to provide sterile filtration of these fluids by prewetting the membrane with a low surface tension fluid such as alcohol. A list of Microfluor II filter applications includes:

Sterile venting of process tanks

Sterile filtration of process air and aseptic filling lines

Sterile venting of lyophilizers

Sterile venting of autoclaves

Sterile air filtration on blow, fill, and seal machines

Sterilizing filtration of fermentation inlet and exhaust air

Sterile filtration of aggressive liquids

Microfluor II filters have been designed to provide exceptionally high flow rates with low differential pressures (Figure 1). Microfluor II filters are available in a range of cartridge and capsule filter configurations to meet any process requirement. Shown in Figure 1 are flow curves for cartridge and capsule filter assemblies at atmospheric (vent) and compressed air conditions. For details of sizing vent and compressed air assemblies, please ask for CUNO Automated Sizing Program assistance.

Figure 1. - Microfluor II Air Flow vs. Diffferential Pressure*

Microfluor II Filter

Air Flow @ Vent Conditions

4.0

3.5

3.0

2.5

2.0

1.5

2.5” Mini Cartridge & Capsules

Differential Pressure (psid)

1.0

0.5

0 20406080100

5” Mini Cartridge

5” Capsule

5” Cartridge

10” Capsule

10” Cartridge

20” Cartridge

Air Flow (SCFM)

40 60 80 100 120 140 160

0.25

0.20

0.15

0.10

0.05

Differential Pressure (bar)