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Host Interface Manual
For use in the US
Document Version 2.3
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Document information
Revision history
Manual version Revision date Changes
2.1 April 2011 Additional screenshots and remarks on page 5
Host Test Code Setting.
2.2 November 2013 • Updated screenshots, on page 5 Host
Communication Setting.
• Additional explanation, on page 8 STAT
Sample Result Upload Setting.
• Note (*6) no sending of multiple orders from
the same test, on page 37 ff – valid from
Software version 02-04.
2.3 March 2016 Modified tip for test selection in real time in the
Communication trace chapter.
2.3 for the US
August 2016
• Used global document version 2.3 as
reference.
• Corrected branding, as necessary.
• Corrected English, as necessary.
Edition notice
This document is for users of the cobas e 411 analyzer.
The contents of this document, including all graphics and photographs, are the
property of Roche. No part of this document may be reproduced or transmitted
in any form or by any means, electronic or mechanical, for any purpose, without
the express written permission of Roche.
Every effort has been made to ensure that the information is correct at the time
of publishing. Not all functionality described in this manual may be available to
all users. Roche Diagnostics reserves the right to change this publication as
necessary and without notice as part of ongoing product development. Such
changes may not immediately be reflected in this document.
Intended use
This document is intended for the US market only.
For prescription use only.
This document describes communication procedure related to communication
method that enables intercommunication between Laboratory Host System,
hereinafter referred to as HOST, and the cobas e 411 analyzer. Specification and
software described herein comply with the following ASTM communication
protocol (HOST communication ASTM higher-layer: High-Level, lower-layer:
Low-Level I/F specification): Specification X12 of ASTM (American Society of
Testing and Materials).
ASTM E1381-91: Specification for Low-Level Protocol to Transfer Messages
Between Clinical Laboratory Instruments and Computer
System
ASTM E1394-91: Standard Specification for Transferring Information
between Clinical Instruments and Computer System
As cobas e 411 analyzer is a successor version of the Elecsys 2010 analyzer, it
upholds Elecsys 2010 analyzer HOST communication protocol. Further, a new
communication protocol is added to keep compatibility with cobas® analyzers.
These two (2) communication protocols such as Elecsys type and cobas type are
selectable. MSRs (Manufacturer Specific Records) that are the original protocol
of Elecsys 2010 analyzer are not supported by cobas e 411 analyzer.
In case of communication problems between a host and the cobas e 411
analyzer please copy the trace file d:\e411\data\log\host_trace.log onto a
removable media and contact the Customer Support Center at 1-800-428-2336.
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Screenshots
Any screenshots in this publication are added exclusively for the purpose of
illustration. Configurable and variable data such as parameters, results, path
names etc. visible therein must not be used for laboratory purposes.
Copyright
©2007-2016, Roche Diagnostics GmbH. All right reserved.
Trademarks
The following trademarks are acknowledged.
COBAS, COBAS C, COBAS E and ELECSYS are trademarks of Roche.
All other product names and trademarks are property of their respective owners.
Feedback
This document was created by Roche Diagnostics GmbH and the Roche
Diagnostics Engineering Operations department. Direct questions or concerns
regarding the contents of this document:
Roche Diagnostics Corporation
Engineering Operations Department
9115 Hague Road
P.O. Box 50457
Indianapolis, IN 46250-0457
USA
Document availability
This document is available on the Roche Diagnostics USA website at
https://usdiagnostics.roche.com
.
Application Code Number (ACN)
Disclaimer for US Customers
Due to the increasing complexity of laboratories and the increase in types of
tests being run, it is critical to use unique host download codes for each test
when mapping codes on your Laboratory Information System (LIS). It is also
strongly recommended to use alpha or alphanumeric codes on your LIS. If
unique LIS test codes are not used when mapping on the LIS, this could cause
a test result from one test to be reported for a different test.
Required actions when using this host interface manual:
• Ensure that the LIS test codes mapped to your LIS are unique for each
test.
• Always identify the instrument source of the results on your LIS.
• Please disregard any application code numbers in this host interface
manual. Refer to the appropriate method sheet, package insert or
application code numbers document for the most current application
code number information.
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Table of contents
Documentation information
Revision history .................................................................................................................................................................................................. 2
Edition notice ...................................................................................................................................................................................................... 2
Intended use ....................................................................................................................................................................................................... 2
Screenshots ......................................................................................................................................................................................................... 3
Copyright .............................................................................................................................................................................................................. 3
Trademarks .......................................................................................................................................................................................................... 3
Feedback .............................................................................................................................................................................................................. 3
Document availability ....................................................................................................................................................................................... 3
Application Code Number (ACN) disclaimer for US Customers ....................................................................................................... 3
Specification of interface
Specification of communication ................................................................................................................................................................... 8
Host Communication setting ......................................................................................................................................................................... 9
Communication cable .................................................................................................................................................................................... 13
Communication test
Communication text ........................................................................................................................................................................................ 16
ASTM communication protocol
ASTM communication protocol .................................................................................................................................................................. 18
Communication data structure ..................................................................................................................................................... 18
Frame structure ................................................................................................................................................................................................ 19
Definition of communication protocol ...................................................................................................................................................... 21
Establishment Phase ........................................................................................................................................................................ 21
Transfer Phase .................................................................................................................................................................................... 24
Termination Phase ............................................................................................................................................................................. 25
Record structure
Record structure .............................................................................................................................................................................................. 28
Syntax .................................................................................................................................................................................................................. 29
Message header record ................................................................................................................................................................................ 32
Message termination record ........................................................................................................................................................................ 34
Request information record ......................................................................................................................................................................... 35
Patient information record ............................................................................................................................................................................ 37
Test order record ............................................................................................................................................................................................. 38
Result record ..................................................................................................................................................................................................... 42
Comment record .............................................................................................................................................................................................. 45
Data alarm list ..................................................................................................................................................................................... 46
Communication trace
Test selection information in real time ..................................................................................................................................................... 50
Disk Type .............................................................................................................................................................................................. 50
Rack Type ............................................................................................................................................................................................. 52
Real time test results ...................................................................................................................................................................................... 53
Result value is within normal range ............................................................................................................................................ 53
Result value is less than normal range ...................................................................................................................................... 53
Result value is a qualitative test ................................................................................................................................................... 54
Control sample ................................................................................................................................................................................... 54
Batch test selection information ................................................................................................................................................................. 55
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Communication error
Example ............................................................................................................................................................................................................... 58
Appendix
Control characters ........................................................................................................................................................................................... 60
Printable characters ........................................................................................................................................................................................ 61
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Specification of interface
1. Specification of communication ................................................................................................................... 8
2. Host communication setting ........................................................................................................................ 9
3. Communication cable ................................................................................................................................ 13
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Specification of communication
Communication between the
cobas e
411 analyzer and HOST is based on
RS-232C connection.
Specification of serial interface is shown as follows:
Item Specification Recommendation Note
Communication Protocol ASTM -
Communication Speed 19200bps/9600bps/4800bps 9600 bps Selectable from GUI
Character Configurations See Table 2 8bit, NONE, 1Stopbit Selectable from GUI
Protocol Type Elecsys type or cobas type Elecsys type Selectable from GUI
Frame Length 247 bytes -
Communication Port 1 port -
Cable Length (maximum) 15m -
Communication Method Half duplex
Table 1: Specification of serial interface
Character configuration is selected from the table below
No. Data bit Parity bit Stop bit
1 7 bit EVEN 2 stop bit
2 7 bit ODD 2 stop bit
3 7 bit EVEN 1 stop bit
4 7 bit ODD 1 stop bit
5 8 bit NONE 2 stop bit
6 8 bit
NONE
1 stop bit
7 8 bit EVEN 1 stop bit
8 8 bit ODD 1 stop bit
Table 2: Character configuration
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Host communication setting
f Utility >System > Host Communication Setting window
Figure 1: Host communication setting
1. Select On or Off at Host Communication window.
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2 Select Protocol Type.
The setting is changeable when Host Communication is OFF.
Figure 2: Protocol Type - Elecsys
Figure 3: Protocol Type - cobas
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Figure 4: Test code
It is mandatory for the Elecsys and cobas mode to also enter the Host Code to
upload results.
Figure 5: Test code selected
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Transfer parameters are shown in in the table below.
Parameter Option
Protocol type
Elecsys / cobas
When selecting Elecsys, it communicates with HOST by Elecsys type.
When selecting cobas, it communicates with HOST by cobas type.
RS232C setting
Speed 19200/9600/4800 Select speed.
Frame
7 bit, EVEN, 2 stop bit/
7 bit, ODD, 2 stop bit/
7 bit, EVEN, 1 stop bit/
7 bit, ODD, 1 stop bit/
8 bit, NONE, 2 stop bit/
8 bit, NONE, 1 stop bit/
8 bit, EVEN, 1 stop bit/
8 bit, ODD, 1 stop bit
Select frame.
Automatic result upload
Yes/No
When YES is selected, result data of a sample is sent to HOST in
real time as soon as all such data are collected.
Communication trace
Yes/No
When YES is selected, communication detail with HOST is traced in
the cobas e 411 analyzer.
STAT Sample Result Upload setting
By Sample When all results are generated, these results are sent to the host.
By Test As soon as one test result is available it is sent to the host.
cobas type setting When Protocol Type is cobas, parameters are as follows.
Automatic recovery of session
Yes/No
This is an automatic reconnection function in case of
communication is disconnected, (HOST Communication Off) under
error described ASTM1381-91 has occurred. When Yes is selected,
the erroneous message and a message sent from HOST before the
reconnection process completed are rejected.
QC additional information
Control name/Lot No.
When ControlName is selected, name of control is sent as sample
ID. When LotNo. is selected the Control Name and the Lot number
is sent to the host, Lot No. is sent as sample ID.
Send result only mode
Yes/No
Only result data is sent. Inquiry for order is not conducted. This
function is not applied to Batch transfer.
Host test code
Host test code setting
Test code between cobas e 411 analyzer and Host defined in Host
Test Code Setting in Utility/Host Communication Setting/Host Test
Code. All used test codes must be entered.
Hint: Also new test application has to be entered.
Table 3: Transfer parameters list
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Communication cable
Connect RS-232C communication cable to the connector at the left side of
cobas e 411 analyzer. The connector is D-SUB9.
Figure 6: Connector and communication cable
Figure 7: Connection diagram
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Communication text
4. Communication text .................................................................................................................................. 16
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Communication text
The table below shows the communication text of the cobas e 411 analyzer.
Item Direction Elecsys type
Real time
Batch
cobas type
Real time
Batch
Inquiry for order
Upload
e 411 > HOST
Yes No Yes No
Order for test request
Download
HOST > e 411
Yes Yes Yes Yes
Result report
Upload
e 411 > HOST
Yes Yes Yes Yes
Inquiry of result
Download
HOST > e 411
No No No No
(yes: equipped, No: not equipped)
Table 4: List of communication text
Note
Patient sample and quality control sample are sent as result data, but not calibration result.
The cobas e 411 analyzer is not equipped with an auto-rerun function. Rerun sample can be
manually defined.
There is no Inquiry for order of a control sample.
Causes of Communication text are shown in the table below.
Text Real/Batch Cause
Inquiry for the requested tests
(upload)
Real
After sample ID is read, inquire of HOST for test selection
information of patient sample to which test selection information is
not registered.
Wait replay from HOST for test selection information for a certain
length of time after the inquiry. If not replied even after a certain
length of time, cancel the inquiry.
Order for test request
(download)
Real
Specify the test selection information for a sample when the test
selection information is inquired.
Batch
HOST specifies the test selection information of a patient sample at
a given timing. Register test selection information before reading
sample ID to use this function.
Result report (upload)
Real
Send result data of patient sample and quality control sample when
all test data of each sample is collected.
Batch
Send result data of patient sample and quality control sample
specified on DataReview window.
Table 5: Causes of communication text
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ASTM communication protocol
5. ASTM communication protocol ................................................................................................................ 18
6. Frame structure ........................................................................................................................................... 19
7. Definition of communication protocol ....................................................................................................... 21
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ASTM communication protocol
The cobas e 411 analyzer employs ASTM communication protocol.
Communication data structure
ASTM communication protocol consists of three layered data structure such as
message, record, and frame. Data is communicated by message. Further, data is
communicated by frame actually. Data structure of a frame varies by protocol.
(1) Elecsys type A message consists of multiple records. A record consists of one or more
frames. A frame comprises not more than one record. In case a record exceeds
240 bytes, a frame is divided into middle frames and a last frame. [ETB] is used
for the middle frame and [ETX] is used for the last frame.
(2) cobas type A message consists of several records. A record consists of one or more frames.
A frame may comprise multiple records. In case of a record exceeds 240 bytes,
a frame is divided into middle frames and a last frame. [ETB] is used for the
middle frame and [ETX] is used for the last frame.
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Frame structure
Frame structure is shown below.
Middle frame, when a message is divided into more than one frame.
[STX] FN text [ETB] CS1 CS2 [CR] [LF]
When the last frame in a message or a frame is a single frame.
[STX] FN text [ETX] CS1 CS2 [CR] [LF]
Field ASCII Code Content Character Note
[STX] 0x02 Start of text 1byte
FN Frame N 1byte 1
Text Communication data Max. 240 byte 2
[ETX]/[ETB] 0x03/0x17 End of text/end of communication block 1byte 3
CS1
Check sum
1byte
4
CS2 1byte
[CR] 0x0d Carriage return 1byte
[LF] 0x0a Line feed 1byte
Table 6: Frame str ucture
Note
1: Way to assign frame No. (FN) is starting from No. 1 to No. 7. When exceeding
No. 7, start from No. 0 to No. 7.
2: Codes, except the following ASCII code, are available for text.
Code Code Code Code Code
[SOH]0x01 [STX]0x02 [ETX]0x03 [EOT]0x04 [ENQ]0x05
[ACK]0x06 [ACK]0x06 [ACK]0x06 [ACK]0x06 [ACK]0x06
[DC3]0x13 [DC4]0x14 [NAK]0x15 [SYN]0x16 [ETB]0x17
3: When a message is 240 bytes or less, use [ETX]. When exceeding 240 bytes, use
[ETB].
4: Add each character code between and inclusive frame No.(FN) and [ETB] or
[ETX]. Display the sum in hexadecimal format. Convert the last two digits into
ASCII code. Code used for Check Sum is 0 to 9 and A to F.
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Example: Check sum calculation method
[STX] 1 T e s t [ETX]
Field Character Hex. format Sum
[STX] [STX] 02h 02h
FN 1 31h 31h
text T 54h 54h
e 65h 65h
s 73h 73h
t 74h 74h
[ETX] [ETX] 03h 03h
Last two digits of the sum. D4h
CS1 D 44h
CS2 4 34h
[CR] 0Dh
[LF] 0Ah
[STX] 1 T e s t [ETX] D 4 [CR] [LF]
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Definition of communication protocol
Low-Level Protocol of ASTM communication protocol is one-way. Response is
generated after the information is sent. Response is not generated simultaneously
with communication. Unlike the other communication protocols, it does not
have master-slave relation. Both cobas e 411 analyzer and HOST enable to
initialize the communication. When establishing send system and receive system,
or when having the action of both the sender and the receiver arranged properly,
the information is communicated by the following three phases:
• Establishment Phase
• Transfer Phase
• Termination Phase
Establishment Phase
In data link layer, both sender and receiver go into one of the following statuses:
• Idle state: status waiting for becoming receiver.
• Starting Establishment Phase at the transmitting side (sender) by
sending [ENQ].
• After receiving [ENQ] from the sender the receiver sends back [ACK].
Number of sender or receiver is one at a time. Without ongoing communication
the cobas e 411 analyzer and the HOST are waiting in idle state. When a message
is sent from one side and the presentation layer requires the data link layer to
send record, one side changes its status from idle to sender. To determine the
direction of communication the sender starts the Establishment Phase by sending
ASCII Code 05h [ENQ] and turns into status sender. The receiver answers this
request by sending ASCII Code 06h [ACK] and turns into status receiver.
Transfer Phase starts when Establishment Phase is completed by receiving
[ACK]. Reception other than [ENQ] is ignored in idle status.
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Figure 8: Establishment phase
In case of error, there are additionally three options for the receiver to respond
[ENQ].
(1) Receiver sends characters These characters are normally sent by using ASCII code 15hex [NAK]
other than [ACK]. when the receiver is busy. The sender waits for a certain length of
time, e.g., the cobas e 411 analyzer waits for 10 seconds, and tries to
establish with another [ENQ]. The cobas e 411 analyzer repeats this
cycle until the number of retries after error reaches six.
(2) Receiver sends [ENQ] The status in which both sender and receiver are trying to change their
status to the sender is called Link Contention in ASTM. When in link
contention, it is defined that communication information of the cobas
e 411 analyzer has a priority. So that HOST must stop sending [ENQ]
and must respond simultaneously by [ACK] or [NAK] when the Link
Contention is detected. On the other hand, the cobas e 411 analyzer
waits for 1 second and replies [ENQ]. The sender repeats this cycle
until receiving characters such as [ACK] or [NAK].
(3) No response from. The sender starts Termination Phase by sending ASCII code 04hex
receiver [EOT] after waiting for 15 seconds, and displays an error message.
(4) Successful procedure of
Establishment Phase is
mentioned above.
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Figure 9: Establishment phase flow chart
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Transfer Phase
After receiving frame, sender discontinues communication until receiving the
response or occurrence of time-out. Usually the receiver notifies by sending
[ACK] that it successfully received the last frame and completes its preparations
to receive the next frame. The receiver notifies by sending [NAK] that the last
frame was not received and it is waiting for receiving the frame.
HOST in status receiver According to the above, there are three options for HOST to respond
the communication of the frame.
HOST sends [ACK] The cobas e 411 analyzer sends the next frame. If the cobas e 411
analyzer has data to be communicated, the cobas e 411 analyzer
continues to send frames.
HOST sends characters other The cobas e 411 analyzer repeatedly sends the frame. This cycle is
than [ACK] repeated until the number of retry in case of error reaches six. At this
moment, the cobas e 411 analyzer starts Termination Phase and
displays an error message by sending [EOT].
No response from HOST. The cobas e 411 analyzer starts Termination Phase by sending [EOT]
(timeout) after 15 seconds and displays an error message.
Response depends on how HOST responds to frame communication
from the cobas e 411 analyzer.
HOST in status sender When the cobas e 411 analyzer is in the receiving status and is waiting
for communication from HOST, there are the following three
scenarios.
HOST sends frame characters After the complete frame is received, the frame No. and the checksum
are checked if they are correct. When the frame is correct, the cobas e
411 analyzer responds by [ACK]. When the frame is incorrect, the
incorrect frame is rejected and [NAK] is returned.
HOST does not complete Time-out occurs when receiving unfinished frame and at the same
frame communication time [EOT] is not received after 15 seconds counted from the last
communication of [ACK] or [NAK] from the cobas e 411 analyzer.
The cobas e 411 analyzer changes to idle status by deleting the last
incomplete message. The line is deemed to be neutral status.
HOST sends [EOT] The cobas e 411 analyzer changes to idle status. Only completely
received frame is deemed to be effective.
Chapter Transfer Phase shows the flowchart of three types of response against
frame communication. An entry point C is selected when Establishment Phase is
completed without any trouble. The entry point C is also the reentry point when
the following frame communication is succeeded. An entry point D is for
retrying when [ACK] is not responded. An entry point E shows change of the
last Phase of this layer.
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Termination Phase
Both sender and receiver change their status into idle in Termination Phase. This
Phase only starts when the sender sends [EOT]. Response from the receiver to
this message is none. When [EOT] is detected at the receiver, it changes to idle
and the line is required to be changed to neutral.
Figure 10: Termination phase flow chart
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Record structure
8. Record structure ......................................................................................................................................... 28
9. Syntax ......................................................................................................................................................... 29
10. Message header record ............................................................................................................................... 32
11. Message termination record ....................................................................................................................... 34
12. Request information record ....................................................................................................................... 35
13. Patient information record ........................................................................................................................ 37
14. Test order record ........................................................................................................................................ 38
15. Result record ............................................................................................................................................... 42
16. Comment record ......................................................................................................................................... 45
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Record structure
The
cobas e
411 analyzer host protocol is compatible with the
cobas®
6000
analyzer series protocol with some minor differences.
No. Object Remarks
1
Carrier no.
cobas e 411 rack analyzer:
When rack no. is unknown, @ is attached in front of <CarrierNo> followed by a delivered value.
cobas e 411 disk analyzer:
The carrier no. is always available on a disk system.
2
Sample ID
When barcode read error occurs, the sample ID is generated as follows: @<Sequence no.>
If a sample barcode read error occurs on a rack system and the rack no. is generated, the sample
cannot be identified by the host.
3 Container Type MC is not micro cup, but indicates reduced value.
4 Result Record cobas type format transmits calculated tests. The host test code numbers can be defined.
5
Comment Record (following
the order record)
The comment record, that follows the order record for patient demographic data is not used.
6
Comment Record (following
the result record)
When no data alarm for message value is available, no comment record is transmitted to host.
Table 7: Record structure
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Syntax
Syntax used in message (records) communicated by the
cobas e
411 analyzer is
shown below.
Communication text Real/Batch
Message syntax
Elecsys type
cobas type
Inquiry for the
requested tests (upload)
Real
H H
Q Q TSREQ^REAL
L L
Order for test request
(download)
Real
H H
P P TSDWN^REPLY
O O
L
L
Batch TSDWN^BATCH
Result report (upload)
H H
Real P P RSUPL^REAL
O O
{ R { R
Batch C-RES } C-RES } RSUPL^BATCH
L L
Table 8: Message syntax
Communication sequences (message flow) of communication message by
application layer are shown below.
cobas e 411 analyzer HOST
(1) Order for test request: real-time Inquiry for the Requested Tests(TSREQ^REAL)
f
g
Order for Test
Request(TSDWN^REPLY)
(2) Order for test request: batch
g
Order for Test
Request(TSDWN^BATCH)
(3) Result report: real-time Result Report(RSUPL^REAL) f
(4) Result report: batch Result Report(RSUPL^BATCH) f
Table 9: Communication sequences
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ASTM syntax is shown below.
(a) Terminating and separating
records character = CR:
Indicates completion of record. ASCII character [CR]
(0Dhex) is required.
(b)
Field separator character =
vertical bar |:
Depending on the second character of a message title record,
it enables to define the field separator character randomly.
However "|" is recommended.
(c)
Repetition field separator
character = backslash \:
When fields consist of repetition of the same data, it is called
repeated field. Repeated field separator character is a
separator between tests of repeated field. Depending on the
message title code, it enables to define the repeated field
separator character randomly.
However "\" is recommended.
(d)
Component separator
character = caret ^:
When fields consist of multiple components, it is called
component field. The component separator separates the
components in a field. Depending on the message title code,
it enables to define the component separator character
randomly.
However "^" is recommended.
(e) Escape character =
ampersand &:
Escape character is defined to represent a separator character
in the field including normal text. Appearance of this
character in such field indicates that the following character
has special meaning. Depending on the message title code, it
enables to define the escape character randomly.
However "&" is recommended.
(f) Expression of special
characters by escape
characters:
Escape sequence, character string starts and ends with &, is
defined as follows. When these sequences are detected in the
field, it is interpreted the corresponding character string.
&F& Field separator character
&S& Component separator character
&R& Repetition separator character
&E& Escape character
Escape sequences other than the above are skipped and handled as null value.
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The table below describes attributes of each field in each record shown in chapter
5, ASTM Communication Protocol.
Column Name of Attributes Description
1 Field position (Pos) Field position. The number also increases by 1, if the field is not used.
2 Order (No.) Sequence of the field. Sequence of the fields in record.
3 Name of Field (Field) Name of relevant field.
4 Type (Type) Typing characters for the fields are any of the following.
ST Character string.
TX Character string group that end is printable.
NM Numeric value. "+" or "-" is attached at the top. If not, the value is deemed to be "+".
When without decimal point, the value is deemed to be integer. Prefix attached to "0",
and suffix attached to "0" of numeric value with decimal point can be anything.
DT Date. Four digits of dominical year. YYYYMMDD (YYYY: dominical year, MM: month,
DD: day), e.g., September 5, 1995 is displayed as 19950905.
TM Set time in 24 hours. HHMMSS (HH: hour, MM: minute, SS: second)
TS Time stamp. Display DT and TM together such as YYYMMDDHHMMSS.
CM Field of combined multiple data by component section separator character.
5 Maximum length (Max) Maximum number of effective characters except escape characters in the relevant field.
6 Elecsys format effective (EV) Indicates if the field is effective or not in record. Fields without X is ignored when received
though they are defined by ASTM.
7 cobas format effective (CV) R = Required field
X = Effective field, if available
8 Comment (Comments) Field description
Table 10: Attributes
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Message header record
Elecsys type format (upload, download)
H|\^&|||xxx|||||||P||[CR]
(1) (2) (3) (6)
cobas type format (upload, download)
H|\^&|||cobas-e411^1|||||host|RSUPL^BATCH|P|1[CR]
(1) (2) (3) (4) (5) (6)(7)
Pos No Field Type Max EV CV
Comments
Elecsys Type Format
cobas Type Format
1 (1) Record Type ID ST 1 X R H is fixed.
2 (2) Delimiter Definition ST 4 X R Four characters, such as field separator character, repeat
separator character, component separator character, and escape
character are defined. The first character is a field separator
character and Record Type ID separator as well. These four
characters are "|\^&".
3 Message Control ID
4 Access Password
5 (3) Sender Name or ID CM 36 X X Indicates sender name.
(Can be omitted)
Delete it when sending from
cobas e 411 analyzer.
Setting is as follows.
(Can be omitted)
<Sender’s device
name>^<Communication
program versio n>
<Sender’s device name> Type:TX
Max: 30
Sending from cobas e 411
analyzer: cobas e 411 is fixed.
Sending from HOST: any
characters within alphanumeric
and "-".
<Communication program
version> Type: NM Max: 5 1 is
fixed.
6 Sender Street Address
7 Reserved Field
8 Sender Telephone
Number
9 Characteristics of
Sender
10 (4) Receiver ID ST 30 X Receiver’s name.
(Can be omitted)
Sending from cobas e 411
analyzer.: host is fixed.
Sending from HOST: any
characters within
alphanumeric and "-".
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Pos No Field Type Max EV CV
Comments
Elecsys Type Format
cobas Type Format
11 (5) Comment or Special
Instructions
Setting is as follows:
<Meaning of
message>^<Cause>
<Meaning of message> Type: ST
Max: 5
TSREQ: TS inquiry.
RSUPL: Transmitting results.
TSDWN: Test request.
<Cause of message> Type: ST
Max: 5
REAL: communication in real time.
BATCH: communication based on
request from cobas e 411/HOST.
REPLY: replay to the request.
12 (6) Processing ID ST 1 X R P is fixed.
13 (7) Version No. NM 1 R 1 is fixed.
14 Date and Time of
Message
Table 11: Message header record
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Message termination record
Elecsys format (upload, download), cobas format (upload, download)
L|1|N [CR]
(1)(2)(3)
Pos No Field Type Max EV CV
Comments
Elecsys Type Format
cobas Type Format
1 (1) Record Type ID ST 1 X R L is fixed.
2 (2) Sequence Number NM 6 X R Indicates sequence No. Normally it is 1.
3 (3) Termination Code ST 1 X R Indicates the end of
communication record.
(Can be omitted)
See table below.
N: Normal end
E: Receiving error, hardware
error, application error
Table 12: Message termination record
Message Message Communication Status Termination Code
Inquiry Normal With response data F
Without response data I
Abnormal All data in record is not defined
(inapplicable message error)
Q
Receiving error
Hardware error
Application error
E
Response, upload download Normal - (*1)
Abnormal All data in record is not defined
(inapplicable message error)
Receiving error
Hardware error
Application error
E
Invalid Record Abnormal Receiving error
Hardware error
Application error
E
(*1) The device does not transmit Termination Code when response or receiving message at download is normal.
Table 14: Termination code list (Elecsys type format)
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Request information record
Elecsys type (upload)
Q|1|^000663^32^@7^2^^SAMPLE^NORMAL||ALL||||||||O[CR]
(1) (2) (3) (4) (5)
cobas type (upload, download)
Q|1|^^000663^32^@7^2^^S1^SC||ALL||||||||O[CR]
(1)(2) (3) (4) (5)
Pos No Field Type Max EV CV
Comments
Elecsys Type Format
cobas Type Format
1 (1) Record Type ID ST 1 X X Q is fixed.
2 (2) Sequence Number NM 6 X X Indicates sequence No. Normally it is 1.
3 (3) Starting Range ID
Number
CM 55/46 X X Indicates the end of
communication record.
^<SampleID>^<SequenceNo>^
<CarrierNo>^<PositionNo>^^
<SampleType>^
<ContainerType>
<SampleID> Type: ST Max: 22
indicates Sample No. (Sample ID.)
<SequenceNo> T ype: NM Max: 4
indicates e411 internal sequence
No.
<CarrierNo> Type: ST Max: 5
indicates carrier No. (Disk/Rack)
<PositionNo> Type: NM Max: 2
indicates position No. in carrier.
<SampleType> Type: ST Max: 7
indicates sample type.
SAMPLE: patients sample, static.
<ContainerType> Type: ST Max: 7
indicates sample cup type.
NORMAL: test tube or sample
cup.
REDUCED: sample cup, only.
Indicates the end of
communication record.
^^<SampleID>^<SequenceNo>
^<CarrierNo>^<PositionNo>^^
<SampleType>^<ContainerType>
<SampleID> Type: ST Max: 22 (*1)
indicates Sample No. (Sample ID.)
<SequenceNo> T ype: NM Max: 4
indicates e411 internal sequence
No.
<CarrierNo> Type: ST Max: 5 (*2)
indicates carrier No. (Disk/Rack.)
<PositionNo> Type: NM Max: 2
indicates position No. in carrier.
<SampleType> Type: ST Max: 2
(*3) indicates sample type.
S1: blood serum.
S2: urine.
S5: others.
<ContainerType> Type: ST Max: 7
(*4) indicates only sample cup type
(SC).
SC: test tube or sample cup.
MC: reduced sample volume
4 Ending Range ID
Number
5 (4) Universal Test ID ST 3 X X ALL is fixed.
6 Nature of Request
Time Limits
7 Beginning Request
Results Data and Time
8 Ending Request
Results Data and Time
9 Requesting Physician
Name
10 Requesting Physician
Telephone Number
11 User Field No. 1
12 User Field No. 2
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Pos No Field Type Max EV CV
Comments
Elecsys Type Format
13 (5) Request Information
Status Codes
ST 1 X X Indicates the objective of the record. Setting is as follows:
O: Order Query (to Host)
A: Cancel the last request (to Host)
(*1) The device does not transmit Termination Code when response or receiving message at download is normal.
(*2) When rack No. of rack version is unknown, @ is attached in front of <CarrierNo> followed by a delivered value.
(*3) Sample Type S1, S2, S5 must be changed to S0 in the next software version because there is no rack type/sample type differentiation on the analyzer. The correct
Sample Type is sent in the order record from the HOST.
(*4) MC indicates reduced volume not micro cup (like the cobas 6000 analyzer series).
Table 14: Request information record
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Patient information record
Elecsys type (upload)
P|1|||||||||||||||||||||||||||||||||[CR]
(1)(2)
Elecsys type (download); cobas type (upload, download)
P|1 [CR]
(1)(2)
Pos No Field Type Max EV CV
Comments
Elecsys Type Format
cobas Type Format
1 (1) Record Type ID ST 1 X X P is fixed.
2 (2) Sequence Number NM 6 X X Indicates sequence No. Normally it is 1.
3 Practice Assigned
Patient ID
4 Laboratory Assigned
Patient ID
5 Patient ID No. 3
6 Patient Name
7 Mother’s Maiden
Name
8 Birthdates
9 Patient Sex
10 Patient Race
11 Patient Address
12 Reserved Field
13 Patient Phone No
14 Attending Physician
ID
15 Special Field 1
Table 15: Patient information record
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Test order record
Elecsys type (upload)
O|1|000663|36^0044^2^^SAMPLE^NORMAL|ALL|R|20050705093416|||||X||||||||||||||O [CR]
(1)(2) (3) (4) (5) (6) (7) (8) (11)
Elecsys type (download)
* 4,*6 *5 *3
O|1|000663|36^0044^2^^SAMPLE^NORMAL|^^^10^2|R|20050705093416|||||N||||||||||||||Q [CR]
(1)(2) (3) (4) (5) (6) (7) (8) (11)
cobas type (upload)
* 4 *5 *2
O|1|000663|6^44^2^^S1^SC|^^^10^2|R||20050705093416||||N||||1|||||||20050705095504|||F[CR]
(1)(2) (3) (4) (5) (6) (7) (8) (9) (10) (11)
cobas type (download)
O|1|000663|6^44^2^^S1^SC|^^^10^2|R||20050705093416||||A||||1||||||||||O[CR]
(1)(2) (3) (4) (5) (6) (7) (8) (9) (11)
Pos No Field Type Max EV CV
Comments
Elecsys Type Format
cobas Type Format
1 (1) Record Type ID ST 1 X R O is fixed.
2 (2) Sequence Number NM 6 X R Indicates sequence No. Normally it is 1.
3 Specimen ID ST 22 X R Indicates sample No. (Sample
ID.)
For control sample, set name
of control.
Indicate sample No. (Sample
ID.)
When barcode read error
occurs, the sample id will be
generated as follows:
@<Sequence no.>
For control sample, the control
name or control name^lot
number is sent to the host,
according to the settings at
the host communication
setting screen.
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Pos No Field Type Max EV CV
Comments
Elecsys Type Format
cobas Type Format
4 (4) CM 30/20 X R Indicates ordered sample.
Setting is as follows:
<SequenceNo>^<CarrierNo>^
<PositionNo>^^<SampleType>^
<ContainerType>
<SequenceNo> Type: NM Max: 4
indicates cobas e 411 analyzer.
internal sequence No.
<CarrierNo> Type: ST Max: 5
indicates carrier No. (Disk/Rack.)
<PositionNo> Type: NM Max: 2
indicates position No. in carrier.
<SampleType> Type: ST Max: 7
indicates sample type.
SAMPLE: patient sample.
CONTROL: control sample.
<ContainerType> Type: ST Max: 7
indicates type of sample cup.
NORMAL: test tube or sample
cup.
REDUCED: sample cup, only.
Indicates ordered sample.
Setting is as follows:
<SequenceNo>^<CarrierNo>^
<PositionNo>^^<SampleType>^
<ContainerType>
<SequenceNo> T ype: NM Max: 4
indicates cobas e 411 analyzer.
internal sequence No.
<CarrierNo> Type: ST Max: 5
indicates carrier No. (Disk/Rack.)
<PositionNo> T ype: NM Max: 2
indicates position No. in carrier.
<SampleType> Type: ST Max: 2
(*2) indicates sample type
S1: blood serum.
S2: urine.
S5: others.
QC: control sample.
<ContainerType> Type: ST-Max: 7
(*1) indicates type of sample cup.
SC: test tube or sample cup.
MC: reduced sample volume.
5 (5) Universal Test ID CM 8 X X Indicates order.
Repeats up to 60 orders. Only up to
18 for test selection information are
avaiölable. Setting is as follows:
^^^<ApplicationCode>^
<Dilution>\…
Repeat delimiter \ for multiple test
selection. For upload, ALL is fixed.
<ApplicationCode> Type: NM
Max: 3 (*4), (*6) indicates e411
Application No.
<Dilution> Type: NM Max: 1
indicates autom atic dilution factor.
(*5)
0: ratio=1 (not diluted).
1: ratio=2
2: ratio=5
3: ratio=10
5: ratio =20
7: ratio=50
9: ratio=100
Indicates order.
Repeats up to 60 orders. Only up to
18 for test selection information are
available. Setting is as follows:
^^^<ApplicationCode>^
<Dilution>\…
Repeat delimiter \ for multiple test
selection.
<ApplicationCode> Type: NM
Max: 3 (*4), (*6) indicates e411
host test No.
The host test no. can be a test
code or a calculated test no (only
for upload).
<Dilution> Type: NM Max: 1 (*5)
indicates automatic dilution ratio.
(also for no dilution attach "^" after
Host Test No. like ^^^10^)
None or
1: ratio=1 (not diluted)
2: ratio=2
5: ratio=5
10: ratio=10
20: ratio=20
50: ratio=50
100: ratio=100
6 (6) Priority ST 1 X R
Indicates priority of patient
samples
R: routine sample.
S: stat sample
Indicates priority of patient
samples
Not used for control samples.
R: routine sample.
S: stat sample
7 Requested/Ordered
Date and Time
8 (7) Specimen Collection
Date and TIme
TS 14 X X Indicates reception date and time of request. Setting is as
follows:
Optional
YYYYMMDDHHMMSS
9 Collection End Time
10 Collection Volume
11 Collector ID
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Comments
Elecsys Type Format
cobas Type Format
12 (8) Action Code ST 2/1 X R Indicates current status of
sample (*3)
X: measured (upload)
N: new sample order (download)
X\Q: control sample (upload)
Q: control sample (download)
A: additional test order (uploa d)
Indicates type of information to
be reported (*3)
N: communication of patient
sample result from analyzer.
(upload)
Q: communication of control
sample result from analyzer
(upload)
A: test order from HOST.
(download)
13 Danger Code
14 Relevant Clinical
Information
15
Date/Time Specimen
Received
16 (9) Specimen Descriptor NM 1 R Indicates sample type (*2)
1: blood serum.
2: urine.
5: others.
17 Ordering Physician
18
Physician’s Telephone
Number
19 User Field No. 1
20 User Field No. 2
21 Laboratory Field No. 1
22 Laboratory Field No. 2
23
(10)
Data/Time Results
Reported or Last
Modified
TS
14 X
Indicates date when all test
results are collected.
Setting from HOST is not
applicable. Setting is as
follows:
YYYYMMDDHHMMSS
24 Instrument Charge to
Computer System
25 Instrument Section ID
26 (11) Report Types ST 1 X R Indicates report type.
Q: response to inquiry. (download)
Z: no response request to inquiry.
(download)
O: from e411 to HOST. (upload)
Indicates type of
communication.
O: test order. (download)
F: communication of result.
(upload)
27 Reserved Field
28 Location or Ward of
Specimen Collection
29 Nosocomial Infection
Flag
30 Specimen Service
31 Specimen Institution
(*1) MC indicates reduced volume not micro cup (like the cobas 6000 analyzer series).
(*2) Except for quality controls, the Specimen Descriptor of Instrument Specimen ID for cobas type is prior to Sample Type when they are mismatched.
(*3) Action Code of already ordered sample for Elecsys type is N: When new order of sample is received, delete existing test information to order the receiving tests.
Same for cobas type as its Action Code is "A" fixed (download).
(*4) Application Code in Universal Test ID.
(*5) See Table 17 for automatic dilution factor/ratio for <Dilution> of Universal Test ID.
(*6) Sending of multiple orders for the same test in one sample record is not allowed.
Table 16: Test order record
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Elecsys type The last digit of application no. is called generation and the host should handle
application no with taking generation into account.. If the host downloads an order
of TSH with application no. =10 and only a different generation of TSH (application
no.=11) is on board then cobas e 411 analyzer uses TSH (application no.=11) for
determination and sends back the result with application no.=11.
cobas type One host test code can be assigned to two or more test generations (e.g., TSH 0(10),
TSH 1(11)). In this case, the latest generation on board is the highest priority for
reagent pack selection.
Automatic dilution
Factor (Elecsys)
Automatic dilution
ration (cobas)
Pipetting volumes
1st dilution 2nd dilution
Sample volume Diluent volume
Diluted sample
volume
Diluent volume
0 1 No sample dilution
1 2 50 µL 50 µL - -
2 5 40 µL 160 µL - -
3 10 20 µL 180 µL - -
4 20 20 µL 180 µL 100 µL 100 µL
5 50 20 µL 180 µL 40 µL 160 µL
6 100 20 µL 180 µL 20 µL 180 µL
Table 17: Automatic dilution factor/ratio list
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Result record
Elecsys type (upload)
R|1|^^^10^^0|0.310|ulU/ml|0.270^4.20|N||F|||20050619094203|20050619101521[CR]
(1)(2) (3) (4) (5) (6) (7) (8) (10) (11)
cobas type (upload)
R|1|^^^10//not|0.310|ulU/ml||N||F||admin|||E1[CR]
(1)(2) (3) (4) (5) (7) (8) (9)
Pos No Field Type Max EV CV
Comments
Elecsys Type Format
cobas Type Format
1 (1) Record Type ID ST 1 X X R is fixed.
2 (2) Sequence Number NM 6 X X Indicates sequence No.
3 (3) Universal Test ID CM 10/20 X X Indicates order.
^^^<ApplicationCode>^
<Dilution>^<pre-dilution>
<ApplicationCode> Type: NM
Max: 3 indicates e411 Application
No.
<Dilution> Type: NM Max: 1
indicates autom atic dilution factor
when ordering.
< pre-dilution > Type: ST Max: 1
0: without pre-dilution.
1: with pre-dilution.
Indicates order.
^^^<ApplicationCode>/<Dilution
>/<pre-dilution>
<ApplicationCode> Type: NM
Max: 3 indicates e411 host test no.
The host test no. can be a test
code or a calculated test no.
Calculated tests can be defined on
the Calc. Test screen. A total of 5
calculated tests can be set. When
all tests requiring calculation are
ordered and successfully
measured, the analyzer
automatically transmits the
calculated tests.
However, the host may not send a
calculation test order.
<Dilution> Type: ST Max: 1
indicates autom atic dilution factor
when ordering: 1, 2, 5, 10, 20, 50,
100
< pre-dilution > Type: ST Max: 11
not: without pre-dilution.
pre-diluted: with pre-dilution.
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Comments
Elecsys Type Format
cobas Type Format
4 (4) Data or Measurement
Value
CM 10 X X Indicates measured value.
Quantitative test format:
<measurement value>
Qualitative test format:
<measurement value>^<cut off
index>
<measurement value> Type: NM
Max: 7 for quantitative tests:
seven numeric including symbol
and decimal places.
">", "<"is attached to the top of the
measured value when measuring
range error occurre d.
Seven spaces (0x20) are
communicated if no result.
For qualitative tests:
1: Positive
0: Border line
-1: Negative
<cut off index> Type: NM Max: 7
seven numeric including symbol
and decimal places.
Seven spaces (0x20) are
communicated if no result.
Indicates measured value.
Quantitative test format:
<measurement
value>>^<message value>
Qualitative test format:
<qualitative value>^<cut off
index>
<measurement value> Type: NM
Max: 7 measured value or 7
spaces if no result.
">", "<" is attached before the
measured value when measuring
range error occurre d. 7 digit
including symbol and decimal
places.
<qualitative value> Type: NM Max:
2
Result message
1: Positive (reac.)
0: Border line (border)
-1: Negative (n-reac.)
<message value> Type: NM Max 2
Result Message code (0～31)
<cut off index> Type: NM Max: 7
Measured value or 7 spaces if no
result.
">", "<" is attached before the
measured value when measuring
range error occurre d. 7 digit
including symbol and decimal
places.
5 (5) Units ST 6 X X Indicates unit name of measurement results.
6 (6) Reference Ranges CM X Indicates normal range.
Indicates QC range when
control sample.
<
Low>^<High>
<Low> Type: NM Max:
7 indicates minimum of the normal
range.
<High> Type: NM Max:
7 indicates maximum of the normal
range.
7 (7) Result Abnormal Flags ST 2 X X Indicates normal/abnormal of
measurement results.
L: less than normal range.
H: more than normal range.
<: less than measured range.
>: more than measured range.
N: Normal
A: Abnormal
Indicates normal/abnormal of
measurement results.
L: less than normal range.
H: more than normal range.
LL: less than measured range.
HH: more than measured range.
N: Normal
A: Abnormal
8 Nature of Abnormality
Testing
9
(8)
Result Status
ST
1
X X Indicates the number of the
tests conducted for the
analytical data.
F: last result.
X: results cannot be done.
R: the result communicated.
V: released result by user.
Y: blocked by system.
+: blocked by user
Indicates the number of the
tests conducted for the
analytical data.
F: initial result.
C: rerun result.
10 Date of Change in
Instrument Normative
values Units
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Comments
Elecsys Type Format
cobas Type Format
11 (9) Operator Identification ST 6 X Indicates operator ID who conducted measurement. HOST can't
set this field.
12 (10) Date/Time Test
Started
TS 14 Indicates time and date when
starting measurement. Setting
is as follows:
YYYYMMDDHHMMSS
13
(11)
Date/Time Test
Completed
TS
14 X
Indicates time and date when
completing measurement.
Setting is as follows:
YYYYMMDDHHMMSS
14 Instrument
Identification
X E1
Table 18: Test order record
Note
cobas type format transmits calculated tests. Elecsys type format does not transmit
calculated tests.
Elecsys type format has no Review by exception function.
cobas
type format does not transmit tests specified by exception alarm, defined in
the Review by exception screen.
Communication of batch results with review by exception alarm flags is based on
option with Review by Exception Results on Send to Host window shown
below.
• On: tests specified by Exception Alarm are communicated.
• Off: tests specified by Exception Alarm are not communicated.
Figure 11: Data selection
When Not Send Host is selected on the window Send to Host, only samples which
were not communicated to the host, are transmitted.
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Comment record
i
The comment record, that follows the order record for patient demographic data is not
used.
Result flag [C-RES] (Comment Record, that follows the Result Record)
Elecsys type (upload)
C|1|I|50^Below measuring range|I[CR]
(1)(2)(3) (4) (5)
cobas type (upload)
C|1|I|50|I[CR]
(1)(2)(3)(4)(5)
Pos No Field Type Max EV CV
Comments
Elecsys Type Format
cobas Type Format
1 (1) Record Type ID ST 1 X X C is fixed.
2 (2) Sequence Number NM 6 X X Indicates sequence No. Normally it is 1.
3 (3) Comment Source ST
1
X X
I is fixed.
4 (4) Comment Text NM/
CM
53/3 X X Data alarm No, and message
for the measured value is
attached.
<Alarm Flag>^<Alarm
Messages>
< Alarm Flag > Type: NM Max: 2
indicates alarm No.
<AlarmMessages>Type: ST Max:
50 indicates alarm message.
Data alarm No for the
measured value is attached.
(*1)
5 (5) Comment Type ST 1 X X I is fixed.
Table 19: Comment record
i
Skip this record when no data alarm for message value was produced.
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Data alarm list
Flag Data Alarm Screen/Printer Elecsys Type Host No. cobas Type Host No.
1 Power Fail/Power Off Cancel Cancel 1 -
2 E.STOP Cancel Cancel 2 -
3 STOP Cancel Cancel 3 -
4 P.STOP/A.STOP Cancel Cancel 4 -
5 S.STOP Cancel Cancel 5 -
6 Recovery Cancel Cancel 6 -
7 Sample Short Samp.S 7 3
8 Assay Reagent Short Reag.S 8 4
9 Diluent Short Reag.S 9 4
10 Pretreatment Reagent Short Reag.S 10 4
11 <Not available> - - -
12 Abnormal Reagent Disk Temperature Reag.T 12 74
13 Abnormal Incubator Temperature Inc.T 13 75
14 Abnormal Measuring Cell Temperature Cell.T 14 77
15 Abnormal System Reagent Temperature SysR.T 15 76
16 System Reagent Short SysR.S 16 62
17 ADC abnormal ADC.E 17 1
18 <Not available> - - -
19 <Not available> - - -
20 <Not available> - - -
21 <Not available> - - -
22 <Not available> - - -
23 <Not available> - - -
24 Calculation Error Calc.? 24 39
25 No Calibration Data Cal.E 25 43
26 Previous Calibration Data Cal.E 26 43
27 <Not available> - - -
28 <Not available> - - -
29 <Not available> - - -
30 <Not available> - - -
31 Assay Reagent Hovering Reag.H 31 69
32 Diluent Hovering Reag.H 32 69
33 Pretreatment Hovering Reag.H 33 69
34 <Not available> - - -
35 Assay Reagent Film Detected Reag.F 35 70
36 Diluent Film Detected Reag.F 36 70
37 Pretreatment Film Detected Reag.F 37 70
38 System Reagent Film Detected Reag.F 38 70
39 <Not available> - - -
40 AB Level Range Over >AB 40 63
41 AB Level Check Error AB.E 41 64
42 Current Range Over >Curr 42 65
43 Current Range Check Error Curr.E 43 66
44 System Reagent Temperature Unstable SysR.U 44 120
45 Sample Clot Detected Samp.C 45 72
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Flag Data Alarm Screen/Printer Elecsys Type Host No. cobas Type Host No.
46 Potential microparticle carryover CarOvr 46 71
47 Sample ID Error Cancel Cancel 47 121
48 Below normal(expected)range L 48 41
49 Above normal(expected)range H 49 40
50 Below measuring range <Test 50 27
51 Above measuring range >Test 51 26
52 Expired RackPack ReagEx 52 101
53 No Sample Samp.S 53 3
54 Sample LLD Inexecution SLLD.E 54 86
55 Sample LLD Noise SLLD.N 55 87
56 Current Range Over(Operation) >Curr 56 99
57 Instrument Factor A FacA 57 122
58 Signal level below limit <SigL 58 100
59 Calc Test Error ClcT.E - 37
- Overflow (*) Over.E - 38
(*) Not in use.
Table 20: Data alarm list
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Communication trace
17. Test selection information in real time ..................................................................................................... 50
18. Real time test results ................................................................................................................................... 53
19. Batch test selection information ................................................................................................................. 55
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Test selection information in real time
An example of communication trace is shown below.
The following trace is shown without Start ([STX][FN]), End
([CR][EXT][CS1[CS2][CR][LF]], and response from each receiver
([ENQ][ACK][EOT]).
i
The HOST is required to send back the SequenceNo, CarrierNo, and Position to the
cobas e 411 analyzer without changing any of them.
If any information is changed, the analyzer sends a cancelation message to the HOST
and the measurement is skipped.
Disk Type
Elecsys type
The
cobas e
411 analyzer sends test selection information such as sample
ID=000004, sequence No.=40, Disk No=0, and Position=5.
H|\^&||||||||||P||[CR]
Q|1|^000004^40^0^5^^SAMPLE^NORMAL||ALL||||||||O[CR]
L|1|I [CR]
Example 1: HOST replies test selection information of sample ID=000004.
H|\^&||||||||||P||[CR]
P|1 [CR]
O|1|000004|40^0^5^^SAMPLE^NORMAL|^^^10^\^^^30^2\^^^40^|R||||||N
||||||||||||||Q
L|1| [CR]
Example 2: HOST replies without order information of sample ID=000004.
H|\^&||||||||||P||[CR]
P|1 [CR]
O|1|000004|40^0^5^^SAMPLE^NORMAL||R||||||N||||||||||||||Z[CR]
L|1| [CR]
The
cobas e
411 analyzer sends a cancel to HOST when HOST does not reply
within 15 seconds.
H|\^&||||||||||P||[CR]
Q|1|^000004^40^0^5^^SAMPLE^NORMAL||ALL||||||||A[CR]
L|1|I [CR]
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cobas type
The cobas e 411 analyzer sends test selection information such as sample
ID=000004, sequence No.=40, Disk No=0, and Position=5.
H|\^&|||cobas-e411^1|||||host|TSREQ^REAL|P|1[CR]
Q|1|^^000004^40^0^5^^S1^SC||ALL||||||||O[CR]
L|1|N[CR]
Example 1: HOST replies test selection information of sample ID=000004.
H|\^&|||host^1|||||cobas-e411|TSDWN^REPLY|P|1[CR]
P|1 [CR]
O|1|000004|40^0^5^^S1^SC|^^^10^\^^^30^2\^^^40^|R||||||A
||||1||||||||||O[CR]
L|1|N[CR]
Example 2: HOST replies without order information of sample ID=000004 or
the generated sample id=@<sequence no.>.
H|\^&|||host^1|||||cobas-e411|TSDWN^REPLY|P|1[CR]
P|1 [CR]
O|1|000004|40^0^5^^S1^SC||R||||||A||||1||||||||||O[CR]
L|1|N[CR
The cobas e 411 analyzer sends a cancel to HOST when HOST does not reply
within 15 seconds.
H|\^&|||cobas-e411^1|||||host|TSREQ^REAL|P|1[CR]
Q|1|^^000004^40^0^5^^S1^SC||ALL||||||||A[CR]
L|1|N[CR]
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Rack Type
Elecsys type
The cobas e 411 analyzer sends inquiry for sample ID=000002, sequence No.=3
Rack No.=@95 and Position=2.
H|\^&||||||||||P||[CR]
Q|1|^000002^3^@95^2^^SAMPLE^NORMAL||ALL||||||||O[CR]
L|1|I[CR]
HOST replies test selection information of sample ID=000002.
H|\^&||||||||||P||[CR]
P|1 [CR]
O|1|000002|3^@95^2^^SAMPLE^NORMAL|^^^10^|R||||||N||||||||||||||Q[CR]
L|1| [CR]
The cobas e 411 analyzer sends inquiry for sequence No.=3 Rack No.=0007,
Position=2, and no sample ID.
H|\^&||||||||||P||[CR]
Q|1|^^3^0007^2^^SAMPLE^NORMAL||ALL||||||||O[CR]
L|1|I[CR]
Note
Key information for a non-barcoded sample is Rack No and position. If barcode read error takes
place for a barcoded sample, the key information is also Rack No and position. In such cases,
the cobas e 411 analyzer inquires after reading Rack No.
cobas type
The
cobas e
411 analyzer sends inquiry for sample ID=000002, sequence No.=3
Rack No.=@95 and Position=2.
H|\^&|||cobas-e411^1|||||host|TSREQ^REAL|P|1[CR]
Q|1|^^000002^3^@95^2^^S1^SC||ALL||||||||O[CR]
L|1|N[CR]
HOST replies test selection information of sample ID=000002.
H|\^&|||host^1|||||cobas-e411|TSDWN^REPLY|P|1[CR]
P|1 [CR]
O|1|000002|3^@95^2^^S1^SC|^^^10^|R||||||A||||1||||||||||O[CR]
L|1|N[CR]
The cobas e 411 analyzer sends inquiry for sequence No.=3 Rack No.=0007,
Position=2 and a generated sample id=@3.
H|\^&|||cobas-e411^1|||||host|TSREQ^REAL|P|1[CR]
Q|1|^^@3^3^0007^2^^S1^SC||ALL||||||||O[CR]
L|1|N[CR]
Note
When it is rack type without sample ID, incl. barcode read error, the cobas e 411 analyzer
inquires after reading Rack No.
i
If a barcode read error occurs and the rack no. is generated, the sample cannot be identified by
the host.
When the rack type communication for a rack does not complete within approximately
40 seconds, the cobas e 411 analyzer sends a cancel to HOST.
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Real time test results
Result value is within normal range
Elecsys type
The cobas e 411 analyzer sends test result of sample ID=000004, sequence
No.=40, Disk No.=0 and Position=5.
H|\^&||||||||||P||[CR]
P|1|||||||||||||||||||||||||||||||||| [CR]
O|1|000004|40^0^5^^SAMPLE^NORMAL|ALL|R|20051220095504|||||X
||||||||||||||O[CR]
R|1|^^^10^^0|1.25|ulU/ml|0.270^4.20|N||F|||20051220095534|
20051220101604|[CR]
R|2|^^^30^2^1|1.52|ng/dl|1.01^1.79|N||F|||20051220103034|
20051220105004|[CR]
R|3|^^^40^^0|1.17|ulU/ml|0.846^2.02|N||F|||20051220110034|
20051220112004|[CR]
L|1| [CR]
cobas type
The cobas e 411 analyzer sends test result of sample ID=000004, sequence
No.=40, Disk No.=0 and Position=5.
H|\^&|||cobas-e411^1|||||host|RSUPL^REAL|P|1[CR]
P|1 [CR]
O|1|000004|40^0^5^^S1^SC|^^^10^\^^^30^2\^^^40^|R||||||N
||||1|||||||20051220095504|||F[CR]
R|1|^^^10//not|1.25^|ulU/ml||N||F||admin|||E1[CR]
R|2|^^^30/2/pre-diluted|0.091^|ng/dl||N||F||admin|||E1[CR]
R|3|^^^40//not|1.17^|ng/ml||N||F||admin|||E1[CR]
L|1|N[CR]
Result value is less than normal range
Elecsys type
The cobas e 411 analyzer sends a test result of sample ID=000002, sequence
No.=3, Rack No.=0007, and Position=2.
H|\^&||||||||||P||[CR]
P|1|||||||||||||||||||||||||||||||||| [CR]
O|1|000002|3^0007^2^^SAMPLE^NORMAL|ALL|R|20051220104418|||||X
||||||||||||||O[CR]
R|1|^^^10^^0|0.163|ulU/ml|0.270^4.20|L||F|||20051220103034|
20051220105004|[CR]
C|1|I|48^Below normal(expected) range|I[CR]
L|1| [CR]
cobas type
The cobas e 411 analyzer sends a test result of sample ID=000002, sequence
No.=3, Rack No.=0007, and Position=2.
H|\^&|||cobas-e411^1|||||host|RSUPL^REAL|P|1[CR]
P|1 [CR]
O|1|000002|3^0007^2^^S1^SC|^^^10^|R||||||N||||1|||||||
20051220104418|||F[CR]
R|1|^^^10//not|0.163|ulU/ml||L||F||admin|||E1[CR]
C|1|I|48|I[CR]
L|1|N[CR]
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Result value is a qualitative test
Elecsys type
The cobas e 411 analyzer sends a test result of sample ID=000010, sequence
No.=442, Rack No.=0005, and Position=1.
H|\^&||||||||||P||[CR]
P|1|||||||||||||||||||||||||||||||||| [CR]
O|1|000010|442^0005^1^^SAMPLE^NORMAL|ALL|R|20051220104418|||||X
||||||||||||||O[CR]
R|1|^^^400^^0|-1^0.303|COI|^|N||F|||20051220110334|
20051220112404|[CR]
L|1| [CR]
cobas type
The cobas e 411 analyzer sends a test result of sample ID=000010, sequence
No.=442, Rack No.=0005, and Position=1.
H|\^&|||cobas-e411^1|||||host|RSUPL^REAL|P|1[CR]
P|1 [CR]
O|1|000010|442^0005^1^^S1^SC|^^^400^|R||||||N||||1|||||||
20051220104418|||F[CR]
R|1|^^^400//not|-1^0.303|COI||N||F||admin|||E1[CR]
L|1|N[CR]
Control sample
Elecsys type
H|\^&||||||||||P||[CR]
P|1|||||||||||||||||||||||||||||||||| [CR]
O|1|PC U2|96^0019^1^^CONTROL^NORMAL|ALL|R|20051220104418|||||X\Q
||||||||||||||O[CR]
R|1|^^^10^^0|1.45|ulU/ml|1.37^1.97|N||F|||20051220110334|
20051220112404|[CR]
L|1| [CR]
cobas type
H|\^&|||cobas-e411^1|||||host|RSUPL^REAL|P|1[CR]
P|1 [CR]
O|1|PC U2|96^0019^1^^QC^SC|^^^400^|||||||Q||||1
|||||||20051220104418|||F[CR]
R|1|^^^400//not|1.26^|ulU/ml||L||F||admin|||E1[CR]
L|1|N[CR]
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Batch test selection information
cobas type.
Download test selection information of sample ID=000051 from HOST.
H|\^&|||host^1|||||cobas-e411|TSDWN^BATCH|P|1[CR]
P|1 [CR]
O|1|000051|^^^^S1^SC|^^^10^/^^^30^2/^^^40^|R||||||A||||1
||||||||||O[CR]
L|1|N[CR]
i
Download of test selection information is new order only. Sequence No. is automatically
numbered by the cobas e 411 analyzer.
The cobas e 411 analyzer can store 2000 tests, e.g., for 1000 samples with two tests. The older
tests are overwritten with a new order if 2000 tests are already stored.
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Communication error
20. Example ...................................................................................................................................................... 58
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Example
An example of communication error is shown below.
Content Alarm Code
A try occurred at message transmission 44-01-01
Communication abort at mess. transmission 44-01-02
Communication abort at receiving message 44-01-03
Message retransmission was unsuccessful (others) 44-01-04
Message retransmission was unsuccessful (retry failed) 44-01-05
Timeout occurred at message transmission 44-01-06
Timeout occurred while receiving message 44-01-07
Communication format was incorrect 44-01-08
Update of a database was not allowed 44-01-09
A hardware error occurred 44-01-10
A software error occurred 44-01-11
Upload is defined but host com. is OFF 44-01-12
Table 21: Communication Error list
Alarm messages are recorded in host trace log.
Figure 12: Host trace log
• S: Send
• R: Recv
• E: Error
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Appendix
21. Control characters ...................................................................................................................................... 60
22. Printable characters ................................................................................................................................... 61
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Control characters
Binary Dec Hex Abbreviation Description
0000 0000 0 00 NUL Null character
0000 0001 1 01 SOH Start of Header
0000 0010 2 02 STX Start of Tex
0000 0011 3 03 ETX End of Text
0000 0100 4 04 EOT End of Transmission
0000 0101 5 05 ENQ Enquiry
0000 0110 6 06 ACK Acknowledgment
0000 0111 7 07 BEL Bel
0000 1000 8 08 BS Backspace
0000 1001 9 09 HT Horizontal Tab
0000 1010 10 0A LF Line feed
0000 1011 11 0B VT Vertical Tab
0000 1100 12 0C FF Form feed
0000 1101 13 0D CR Carriage return
0000 1110 14 0E SO Shift Out
0000 1111 15 0F SI Shift In
0001 0000 16 10 DLE Data Link Escape
0001 0001 17 11 DC1 Device Control 1
0001 0010 18 12 DC2 Device Control 2
0001 0011 19 13 DC3 Device Control 3
0001 0100 20 14 DC4 Device Control 4
0001 0101 21 15 NAK Negative Acknowledgement
0001 0110 22 16 SYN Synchronous Idle
0001 0111 23 17 ETB End of Trans. Block
0001 1000 24 18 CAN Cancel
0001 1001 25 19 EM End of Medium
0001 1010 26 1A SUB Substitute
0001 1011 27 1B ESC Escape
0001 1100 28 1C FS File Separator
0001 1101 29 1D GS Group Separator
0001 1110 30 1E RS Record Separator
0001 1111 31 1F US Unit Separator
0111 1111 127 7F DEL Delete
Table 22: Control characters
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Printable characters
Binary Dec Hex Char Binary Dec Hex Char Binary Dec Hex Char
0010 0000 32 20 blank 0100 0000 64 40 @ 0110 0000 96 60 `
0010 0001 33 21 ! 0100 0001 65 41 A 0110 0001 97 61 a
0010 0010 34 22 " 0100 0010 66 42 B 0110 0010 98 62 b
0010 0011 35 23 # 0100 0011 67 43 C 0110 0011 99 63 c
0010 0100 36 24 $ 0100 0100 68 44 D 0110 0100 100 64 d
0010 0101 37 25 % 0100 0101 69 45 E 0110 0101 101 65 e
0010 0110 38 26 & 0100 0110 70 46 F 0110 0110 102 66 f
0010 0111 39 27 ' 0100 0111 71 47 G 0110 0111 103 67 g
0010 1000 40 28 ( 0100 1000 72 48 H 0110 1000 104 68 h
0010 1001 41 29 ) 0100 1001 73 49 I 0110 1001 105 69 i
0010 1010 42 2A * 0100 1010 74 4A J 0110 1010 106 6A j
0010 1011 43 2B + 0100 1011 75 4B K 0110 1011 107 6B k
0010 1100 44 2C , 0100 1100 76 4C L 0110 1100 108 6C l
0010 1101 45 2D - 0100 1101 77 4D M 0110 1101 109 6D m
0010 1110 46 2E . 0100 1110 78 4E N 0110 1110 110 6E n
0010 1111 47 2F / 0100 1111 79 4F O 0110 1111 111 6F o
0011 0000 48 30 0 0101 0000 80 50 P 0111 0000 112 70 p
0011 0001 49 31 1 0101 0001 81 51 Q 0111 0001 113 71 q
0011 0010 50 32 2 0101 0010 82 52 R 0111 0010 114 72 r
0011 0011 51 33 3 0101 0011 83 53 S 0111 0011 115 73 s
0011 0100 52 34 4 0101 0100 84 54 T 0111 0100 116 74 t
0011 0101 53 35 5 0101 0101 85 55 U 0111 0101 117 75 u
0011 0110 54 36 6 0101 0110 86 56 V 0111 0110 118 76 v
0011 0111 55 37 7 0101 0111 87 57 W 0111 0111 119 77 w
0011 1000 56 38 8 0101 1000 88 58 X 0111 1000 120 78 x
0011 1001 57 39 9 0101 1001 89 59 Y 0111 1001 121 79 y
0011 1010 58 3A : 0101 1010 90 5A Z 0111 1010 122 7A z
0011 1011 59 3B ; 0101 1011 91 5B [ 0111 1011 123 7B {
0011 1100 60 3C < 0101 1100 92 5C \ 0111 1100 124 7C |
0011 1101 61 3D = 0101 1101 93 5D ] 0111 1101 125 7D }
0011 1110 62 3E > 0101 1110 94 5E ^ 0111 1110 126 7E ~
0011 1111 63 3F ? 0101 1111 95 5F _
Table 23: Printable characters
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