Leica SCN400, SL801 User Manual

Virtual Microscopy Solutions

Leica Microsystems’ Complete Virtual Microscopy Product Range

Of Course We Scan

Leica SCN400

The fast, reliable, and fl exible way to scan and digitize your slides

• High resolution – high-quality, high-contrast images

• Always in focus – patented Dynamic Focus Tracking

• Reliable, precise scans – Minimize the risk of failed scans

• Unprecedented rapid scanning speed

Leica SL801

The fast, reliable, and fl exible way to handle large volumes of slides

• Automatically scan up to 384 slides without

• Easy upgrade – Leica SCN400 can be retrofi tted with

• Flexibility – use automatic scanning with user-defi ned

• Convenience – load slides as needed, even during the

with specially designed optics

reveals greater specimen detail

manual interaction

Leica SL801 at the user’s facility

settings or fully interactive mode for complete control

scanning process

Ariol Platform

Unmatched fl exibility in microscope-based slide scanning with
the Ariol system

• Highest quality brightfi eld and fl uorescent slide scanning

• Flexible hardware confi guration with user selected

objectives and fi lters

• Diagnostic image quality with advanced optional

analysis capabilities

• Professional integrated reports with gold standard

scoring protocols

Scanning is Just the Beginning

Manage

Use SlidePath’s Digital Image Hub for fl exible online access

• User defi ned image associated data for intuitive archiving,

search and retrieval

• Centralized multi-format image library including digital

slides, DICOM and standard image formats

• Easy to use folder structure for effi cient image management

• Communication protocols for seamless integration

with third party systems

• Flexible storage architecture ensures system scalability

and future proofi ng

Increase Effi ciency

Intuitive software workfl ows reduce time and cost & increase quality

• Rapidly review image cohorts with multi-parametric

searching and high throughput review

• User-defi ned glossaries and dictionaries standardize

nomenclature resulting in accurate data mining and analysis

• Use OpTMA for automatic core identifi cation and rapid core

review to increase TMA throughput and reduce risk of error

• Navigate images, record data and create annotations within

the slide viewer

Share Informat

Rapid access to slides any

• Support multi-users co

image library

• Reduce time taken for

remote slide reading

• Conferencing tool simu

environment for rapid s

• Review multiple image

viewing and improved s

• Online solution require

Data Security

Ensure safety, control, and compliance of your complete image
management system

• Multi-level user control ensures correct access rights to

defi ned image and data collections

• Unique user names and encrypted passwords required

for system access

• Comprehensive audit trails and controls for 21 CFR part 11

• Secure system architecture and backup capabilities

e-Learning

Modernize slide-based learning with cutting edge technology

• Reduce costs and increase class size with SlidePath’s Digital

SlideBox

• Maximize teaching effi ciency and standardize course

material – same digital slide instead of similar glass slides

• Integrate rare cases and expose students to cases they

would not see with fragile glass slides

• Students have 24/7 access to course material

• Easy integration of course content, slides, and questionnaires

in a single online system

• Improve quality assurance and continuing professional

development schemes with standardized content and
no shipping time or costs

The Image is Not the End

Flexible Image Analysis
for Your Research Laboratory

SlidePath’s Tissue IA provides high-throughput, web-enabled
analysis for digital slides

• Web-deployed software enables control and review of

image analysis from anywhere

• Flexible solution for whole slide, region of interest

or TMA analysis

• Standard algorithms (membrane, nuclear, and positive pixel)

can be adapted for multiple biomarker and tissue types

• Grid computing approach enables whole slide analysis

• Scalable solution to increase processing power

and decrease analysis time

Quantify Biomarkers
for Clinical Diagnostics

The Ariol platform couples high quality imaging with advanced
intelligent analysis

Clinical Her2/neu brightfi eld IHC, ER, PR in breast cancer analysis

• Gold-standard scoring protocols fully supported

(Allred scoring, Histoscoring)

• Unique region-of-interest analysis readily integrates

into existing pathology workfl ows

• Produce case reports with easy export into information

management systems

Clinical Her2/neu FISH analysis

• Capture total gene signal through full z-stack ensures

that all information is analyzed

• Automatic signal counting expressed in an easy to read

per-nucleus table

• Bring fl uorescence analysis out of the dark room and

increase speed of review

• Archive digital images for permanent non-fade records

Original and fi nal image after processing with SlidePath‘s Tissue IA.
Nuclear staining on selected inclusion regions have been classifi ed as strongly
positive (red), moderately positive (orange), weakly positive (yellow) and negative
based on input parameters.

SlidePath applications are not cleared by the FDA , Health Canada or in the EU for diagnostic or clinical use. All applications are intended solely for use in the research or educational setting, such as university or pharmaceuti­cal development. These applications are described as Research Applications or Research Use Only.

Nuclear (ER & PR), Membrane (Her2/neu), and
FISH (Her2 FISH) capture and analysis (from top to bottom).

“With the user, for the user”
Leica Microsystems

Leica Microsystems operates globally in four divi sions,
where we rank with the market leaders.

Life Science Division

•

The Leica Microsystems Life Science Division supports the
imaging needs of the scientifi c community with advanced
innovation and technical expertise for the visualization,
measurement, and analysis of microstructures. Our strong
focus on understanding scientifi c applications puts Leica
Microsystems’ customers at the leading edge of science.

Industry Division

•

The Leica Microsystems Industry Division’s focus is to
support customers’ pursuit of the highest quality end result.
Leica Microsystems provide the best and most innovative
imaging systems to see, measure, and analyze the micro­structures in routine and research industrial applications,
materials science, quality control, forensic science inves­tigation, and educational applications.

Biosystems Division

•

The Leica Microsystems Biosystems Division brings his­topathology labs and researchers the highest-quality,
most comprehensive product range. From patient to pa­thologist, the range includes the ideal product for each
histology step and high-productivity workfl ow solutions
for the entire lab. With complete histology systems fea­turing innovative automation and Novocastra™ reagents,
Leica Microsystems creates better patient care through
rapid turnaround, diagnostic confi dence, and close cus­tomer collaboration.

Medical Division

•

The Leica Microsystems Medical Division’s focus is to
partner with and support surgeons and their care of pa­tients with the highest-quality, most innovative surgi cal
microscope technology today and into the future.

The statement by Ernst Leitz in 1907, “with the user, for the user,” describes the fruitful collaboration
with end users and driving force of innovation at Leica Microsystems. We have developed fi ve
brand values to live up to this tradition: Pioneering, High-end Quality, Team Spirit, Dedication to
Science, and Continuous Improvement. For us, living up to these values means: Living up to Life.

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and representatives in more than 100 countries

by Leica Microsystems CMS GmbH, Wetzlar, Germany, 2011

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is a registered trademark of Genetix Europe Limited, Unit 7, Queens Park, Queensway North, Gateshead, Tyne and Wear, NE11 0QD UK

®

Order no.: English 914 722 • X/11/DX/Br.H. • Ariol

The Ariol Hersight, ERsight, PRsight and PathVysion (tm) are for in vitro diagnostic use, all other assays are for research only. Not for use in diagnostic procedures.

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