Leica TCS LSI User Manual
Leica TCS LSI
The World‘s First Super Zoom Confocal!
From Gene to Cell - from Cell to Embryo
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The World‘s First Super Zoom Confocal
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In Vivo
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Freedom for New Reserach
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Easy to Achieve
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- Large Scale Imaging
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An increasing number of scientists extend their
focus of bio-research from single cell studies to
entire organisms, analyzing the complex interaction within whole animals. Thus, modern
developmental biology is an emerging field of
research, studying the dynamics of cell growth,
differentiation processes and the development
of organs
As living organisms grow in three dimensions
these studies require imaging systems which provide - beside high resolution – a large workspace
and field of view. Leica Microsystems introduces
a pioneering imaging system for developmental
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biology which provides all these features in one:
the new Leica TCS LSI.
in vivo
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Leica TCS LSI
The world‘s first super zoom
confocal!
Leica TCS LSI is the first super zoom 3D-confocal,
offering high resolution plus large field of view for
in vivo
(LSI) platform provides generous workspace and
adapts perfectly to the experiment needs of
native specimen analysis.
True confocal technology is used to provide crystal clear images of highest spectral resolution,
revealing finest details of the model organism, no
matter if drosophila fly, mouse, plant or zebra fish.
An automated optical zoom system allows for
seamless magnification change on demand,
easy switching from overview to details and
free 3D navigation through the specimen.
imaging. The new Large Scale Imaging
Gain new insights with
TCS LSI and study processes of life – from egg to
fly, from embryo to adult.
in vivo
imaging by Leica
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Benefit from freedom for new applications offered by Leica TCS
LSI, feel free to zoom in and out and travel time resolved in all dimensions
in vivo
through your specimen.
Leica TCS LSI
New perspectives of life: From cell to animal
A system tailored to your needs
With the Leica TCS LSI, study the process of life from embryo to
adult. Due to the functional and workflow oriented design, even
sample preparation and orientation can be directly performed on
the imaging system.
Take advantage of the combination of high-resolution confocal
technology and large field macro zoom imaging. A generous
workspace provides extended freedom for
Zoom in and out, from overview to area of interest at highest resolution and obtain fascinating results.
in vivo
experiments.
Features
Zoom factor up to 16x
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Field of view up to 16 mm
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Generous workspace
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Free sample access by wing door
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Easy sample manipulation
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Largest motorized z-control
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Large xy-travel range for optimal
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positioning
Precise z-control by galvo stage
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From cell to embryo
Leica TCS LSI enables you to visualize cell growth and the fascinating differentiation of cells into organs in real life from cell to
embryo – in one system!
Identify new pathways from gene to cell, from cell to animal; or examine the influence of genomic defects on the whole animal.
Study time resolved 4D processes at highest resolution easily as
Advanced Time Lapse software is provided for in vivo studies.
Analyze protein interactions or test the influence of drugs
in bio-medical research.
Visualize the development of life: the Leica TCS LSI Large Scale
Imaging System provides highest image quality, easy operation
and maximum flexibility.
in vivo
Largest workspace...
...for finest insights
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Leica TCS LSI – The Large Scale Ima
High Resolution in 2D and 3D
From micro to macro ...
Get the big picture of large specimen in 2D or 3D. Use the
Leica LAS AF 3D-visualisation package for reconstruction of
Drosophila larvae. (Left)
... zoom in seamlessly into the finest details!
The motorized optical zoom offers the advantage of flexible
magnification to identify the finest details of your model
organism. Backbone details of zebra fish or eye of the
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drosophila larvae, both in highest resolution. (Bottom)
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