Labconco 794001010, 794001015, 794001030, 794001040, 794001050 Instruction Manual

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Original instructions

FreeZone® Triad™ Freeze Dryers

Models

7940010** Series

Original instructions

Copyright © 2017 Labconco Corporation. The information contained in this manual and the accompanying products are copyrighted and all rights reserved by Labconco Corporation. Labconco Corporation reserves the right to make periodic design changes without obligation to notify any person or entity of such change.

Warranty

Labconco Corporation provides a warranty to the original buyer for the repair or replacement of parts and reasonable labor as a result of normal and proper use of the equipment with compatible chemicals. Broken glassware and maintenance items, such as filters, gaskets, light bulbs, finishes and lubrication are not warranted. Excluded from warranty are products with improper installation, erratic electrical or utility supply, unauthorized repair and products used with incompatible chemicals.

The warranty for FreeZone® Freeze Dry Systems will expire one year from date of installation or two years from date of shipment from Labconco, whichever is sooner. Warranty is non-transferable and only applies to the owner (organization) of record.

Buyer is exclusively responsible for the set-up, installation, verification, decontamination or calibration of equipment. This limited warranty covers parts and labor, but not transportation and insurance charges. If the failure is determined to be covered under this warranty, the dealer or Labconco Corporation will authorize repair or replacement of all defective parts to restore the unit to operation. Repairs may be completed by 3rd party service agents approved by Labconco Corporation. Labconco Corporation reserves the rights to limit this warranty based on a service agent’s travel, working hours, the site’s entry restrictions and unobstructed access to serviceable components of the product.

Under no circumstances shall Labconco Corporation be liable for indirect, consequential, or special damages of any kind. This warranty is exclusive and in lieu of all other warranties whether oral, or implied.

Returned or Damaged Goods

Do not return goods without the prior authorization from Labconco. Unauthorized returns will not be accepted. If your shipment was damaged in transit, you must file a claim directly with the freight carrier. Labconco Corporation and its dealers are not responsible for shipping damages.

The United States Interstate Commerce Commission rules require that claims be filed with the delivery carrier within fifteen (15) days of delivery.

Limitation of Liability

The disposal and/or emission of substances used in connection with this equipment may be governed by various federal, state, or local regulations. All users of this equipment are required to become familiar with any regulations that apply in the user’s area concerning the dumping of waste materials in or upon water, land, or air and to comply with such regulations. Labconco Corporation is held harmless with respect to user’s compliance with such regulations.

Contacting Labconco Corporation

If you have questions that are not addressed in this manual, or if you need technical assistance, contact

Labconco’s Customer Service Department or Labconco’s Product Service Department at 1-800-821-5525 or 1-816-333-8811, between the hours of 7:30 a.m. and 5:30 p.m., Central Standard Time.

Part #7343300, Rev. A

ECO L423

Original instructions

TABLE OF CONTENTS

CHAPTER 1: INTRODUCTION	1
Intended Use	1
Freeze Dry Process	1
Freeze Dry Rates	2
Freeze Dry Capacity	3
Samples Containing Volatile Substances	4
About This Manual	4
Typographical Conventions	5
CHAPTER 2: PREREQUISITES	6
Electrical Requirements	6
Location Requirements	7
Vacuum Pump Requirements	7
CHAPTER 3: GETTING STARTED	8
Unpacking Your Freeze Dryer	8
Freeze Dryer Components	9
Setting Up Your Freeze Dryer	9
Component Identification	10
Vacuum Pump Connection	11
Electrical Connection	12
Chemical Resistance of Freeze Dryer Components	12
Solvent Safety Precautions	14
CHAPTER 4: LYO-WORKS™ OPERATING SYSTEM	15
Control Panel	16
Initial Power Up	16
Touch Screen Operation	17
Home screen	17
Main Menu Icons	17
Moving between Menu Screens	17
Function Indicator Bar	17
System Parameters Display	18
Operation Buttons (Program, Manual, Vacuum, Defrost)	19
Programs screen	20
Data Logging screen	22
Settings screen	23

Original instructions

Language	23
Time & Date	23
Units	24
Security	24
Alerts	25
Configure Email Settings	26
Maintenance	27
Vacuum Pump Settings	27
Refrigeration System Settings	27
Freeze Dryer Line Voltage Offset	27
Vacuum Pump Protection	27
Calibration	28
Display	29
Network	30
Sensors screen	30
End Point Detection screen	30
Help screen	32
Diagnostics	32
User’s Manual	32
About	32
CHAPTER 5: USING YOUR FREEZE DRYER	33
Operation Checklist	33
Vacuum Pump Ballast Setting	33
Sample Freezing	33
Shelf Loading	34
Setting the Operating Vacuum Level	34
Freeze Drying Inside the Chamber	36
Manual Mode with Pre-Frozen Samples	36
Manual Mode with Unfrozen Samples	37
Program Mode with Pre-Frozen Samples	37
Program Mode with Unfrozen Samples	38
Stopping the Freeze Dry Cycle	38
Freeze Drying Using Sample Valves (In-Flask Mode)	39
Stoppering Vials	40
Vacuum Break/Backfilling	40
Defrosting	41
Alerts	41
Copy (Export) a Data Log File	43
Download a Data Log File via Ethernet	43
Copy a Program	44
CHAPTER 6: MAINTAINING YOUR FREEZE DRYER	45
Service Safety Precautions	45
Routine Maintenance Schedule	45

Original instructions

CHAPTER 7: TROUBLESHOOTING	47
Vacuum Pump	47
Gaskets, Tubing, Connections, Sample Valves	48
System Components & Collector Chamber Isolation	50
Refrigeration Module Operation	52
APPENDIX A: FREEZE DRYER COMPONENTS	53
APPENDIX B: FREEZE DRYER DIMENSIONS	55
APPENDIX C: FREEZE DRYER SPECIFICATIONS	56
Electrical Specifications	56
Environmental Conditions	57
APPENDIX D: FREEZE DRYER ACCESSORIES	58

Original instructions

CHAPTER 1

INTRODUCTION

Congratulations on your purchase of a Labconco FreeZone® Triad™ Freeze Dry System, which is designed for laboratory lyophilization procedures. The refrigerant used in the refrigeration system is HCFC-free so it will not endanger the environment. The unit is easy to install and maintain. Proper care and maintenance of this product will result in many years of dependable service.

Intended Use

The Labconco Freeze Dryers described in this manual are intended for laboratory use to facilitate the lyophilization process.

Freeze Dry Process

Freeze drying is an important process in sample preparation and for the preservation and storage of biologicals, pharmaceuticals and foods. Of the various methods of dehydration, freeze drying (lyophilization) is especially suited for substances that are heat sensitive. Other than food processing (e.g., coffee, whole dinners), freeze drying has been extensively used in the development of pharmaceuticals (e.g., antibiotics) and preservation of biologicals (e.g., proteins, plasma, viruses and cell lines). The nondestructive nature of this process has been demonstrated by the retention of viability in freeze dried viruses and microorganisms.

Freeze drying is a process whereby water or other solvent is removed from frozen material by converting the frozen water directly into vapor without the intermediate formation of liquid water. The basis for this sublimation process involves the absorption of heat by the frozen sample in order to vaporize the ice; the use of a vacuum pump to enhance the removal of water vapor from the surface of the sample; the transfer of water vapor to a collector; and the removal of heat by the collector in order to condense the water vapor. In essence, the freeze dry process is a balance between the heat absorbed by the sample to vaporize the ice, and the heat removed from the collector to convert the water vapor into ice.

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Original instructions

Chapter 1: Introduction

Freeze Dry Rates

The efficiency of the Freeze Drying process is dependent upon the surface area and the thickness of the sample, the collector temperature and vacuum obtained, the eutectic point and solute concentration of the sample. It is important to remember these factors when trying to obtain efficient utilization of your Freeze Dry system. A listing of selected materials and their approximate drying times are shown in Table 1 for your reference.

			Table 1

SAFE TEMPERATURE AND DRYING TIMES
FOR SELECTED MATERIALS
Material	Safe	Collector		Hours
10mm Thick	Temperature	Temperature		(Approx.)
	°C	°C
Milk	-5	-40		10
Urea	-7	-40		10
Blood Plasma	-10 to -25	-40		16
Serum	-25	-40		18
Vaccinia	-30 to -40	-50		22
Influenza Vaccine	-30	-50		24
Human Tissue	-30 to -40	-50		48
Vegetable Tissue	-50	-80		60

*Total sample quantities are contingent on various freeze dryer capacities.

Up to the point of overloading the system, the greater the surface area of the sample, the faster the rate of freeze drying. By contrast, for a given surface area, the thicker the sample the slower the rate of freeze drying. This is based on the fact that the heat of sublimation is usually absorbed on one side of the frozen sample and must travel through the frozen layer to vaporize water at the other surface. In addition, as the sample is freeze dried, the water vapor must travel through the layer of dried material. The thicker the sample, the greater the chance that the dried layer may collapse which would cause an additional decrease in the rate of freeze drying.

The surface area and thickness of the sample can usually be ignored when each sample contains only a few milliliters. However, for larger volumes, the samples should be shell frozen to maximize the surface area and minimize the thickness of the sample. The volume of the freeze dry flask should be two to three times the volume of the sample.

In order for lyophilization to occur, ice must be removed from the frozen sample via sublimation. This is accomplished by the collector and the vacuum pump. The collector, which should be at least 15 to 20°C colder than the eutectic temperature (melting temperature) of the sample, traps vapor as ice. Since the vapor pressure at the collector is lower than that of the sample, the flow of water vapor is from the sample to the collector. Since this vapor diffusion process occurs very slowly under normal atmospheric conditions, a good vacuum is essential to maintain an

2	Product Service 816-333-8811 or 1-800-522-7658

Original instructions

Chapter 1: Introduction

efficient rate. In many applications, the maintenance of a vacuum of 0.133 mbar or less is recommended.

The rate of freeze drying is directly proportional to the vapor pressure and the vapor pressure is dependent upon both eutectic temperature and solute concentration of the sample. For example, a solution of sodium chloride and water would freeze dry at a slower rate than pure water. The eutectic temperature of a sodium chloride solution is about –21°C and at this temperature the vapor pressure is about 1/16 that of water at 0°C. Although the eutectic temperature is not dependent upon the concentration of sodium chloride, the vapor pressure of the water would decrease as the concentration of sodium chloride increased. This is due to the fact that as the solute concentration increases, less of the surface area of the frozen sample is occupied by water. In general, most solutions or biological samples will have a eutectic temperature of –10 to –25°C. However, if the sample contains a simple sugar such as glucose or if the sample is animal or plant tissue, the eutectic temperature may be as low as –30° to –50°C.

Freeze Dry Capacity

The volume of a sample that can be freeze dried at one time is related to factors discussed previously and the size and design of the freeze dry system. With any given instrument, the capacity is based on the surface area of the sample; the eutectic temperature and concentration of the sample; and the rate and amount of heat transferred to the frozen sample. Of these factors, the eutectic temperature is the most important factor in determining the amount of sample that can be freeze dried at one time, particularly when flasks are used. This is because as the eutectic temperature decreases, the vapor pressure decreases but the rate of heat absorption by the sample does not change. This tends to promote melting of the sample, which leads to a marked increase in vapor pressure and ultimately overloads the collector and vacuum pump. Samples that have eutectic temperatures of –20°C or lower should be placed on the freeze dry system one flask at a time so that the vacuum in the system may recover before adding another sample to the system. If the vacuum does not recover, the capacity of the freeze dry system has been exceeded and the sample should be removed.

If there is a problem with a particular type of sample melting when placed on the freeze dry system, dilution of the sample with more water or providing some insulation around the flask (when utilizing In-Flask mode) to decrease the rate of heat absorption by the sample may help.

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Original instructions

Chapter 1: Introduction

Samples Containing Volatile Substances

In certain cases the solvent in a sample to be freeze dried may contain volatile components such as acetonitrile, methanol, acetic acid, formic acid or pyridine. In addition to these substances having an effect on the eutectic temperature, they may increase the vapor pressure at the surface of the sample. Also, compared to water, they will require the absorption of less heat for sublimation to occur. Hence, samples that contain volatile substances will have a greater tendency to melt, particularly when placed in flasks or exposed to room temperature. If a sample containing a volatile substance tends to melt when placed on a freeze dry system, dilution of the sample with more water will help keep the sample frozen. For example, a 0.2M solution of acetic acid is much easier to freeze dry than a 0.5M solution.

About This Manual

This manual is designed to help you learn how to install, use, and maintain your Freeze Dryer. Instructions for performing routine maintenance and making minor modifications to your Freeze Dryer are also included.

Chapter 1: Introduction provides a brief overview of the Freeze Dryer, explains the organization of the manual, and defines the typographical conventions used in the manual.

Chapter 2: Prerequisites explains what you need to do to prepare your site before you install your Freeze Dryer. Electrical requirements are discussed.

Chapter 3: Getting Started contains the information you need to properly unpack, inspect and install your Freeze Dryer.

Chapter 4: Lyo-Works Operating System describes the display screens and user interface software that controls the Freeze Dryer.

Chapter 5: Using Your Freeze Dryer discusses the basic operation of your Freeze Dryer. Information on how to attach samples and run the Freeze Dryer is included.

Chapter 6: Maintaining Your Freeze Dryer explains how to perform routine maintenance on your Freeze Dryer.

Chapter 7: Troubleshooting contains a table of problems you may encounter while using your Freeze Dryer, including the probable causes of the problems, and suggested corrective actions.

Appendix A: Freeze Dryer Components contains labeled diagrams of the components of the Freeze Dryer.

Appendix B: Freeze Dryer Dimensions contains diagrams showing the dimensions for the Freeze Dryer.

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Original instructions

Chapter 1: Introduction



Appendix C: Freeze Dryer Specifications contains product specifications.

Appendix D: Freeze Dryer Accessories see www.labconco.com for a complete list of Freeze Dry accessories.

Typographical Conventions

Recognizing the following typographical conventions will help you understand and use this manual:

Book, chapter, and section titles are shown in italic type (e.g., Chapter 3: Getting Started).

Steps required to perform a task are presented in a numbered format.

Comments located in the margins provide suggestions, reminders, and references.

Critical information is presented in boldface type in paragraphs that are preceded by the exclamation icon. Failure to comply with the information following an exclamation icon may result in injury to the user or permanent damage to your Freeze Dryer.

Important information is presented in capitalized type in paragraphs that are preceded by the pointer icon. It is imperative that the information contained in these paragraphs be thoroughly read and understood by the user.

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Original instructions

CHAPTER 2

PREREQUISITES

Before you install your Freeze Dryer, you need to prepare your site for installation. Carefully examine the location where you intend to install your Freeze Dryer. You must be certain that the area is level and of solid construction. An electrical source must be located near the installation site.

Carefully read this chapter to learn:

Electrical supply requirements.

Vacuum pump requirements.

Refer to Appendix C: Freeze Dryer Specifications for complete Freeze Dryer electrical and environmental conditions, specifications and requirements.

Electrical Requirements

230V models

o 20 Amp dedicated single phase circuit.

oProperly grounded receptacle that matches the plug supplied with the unit, (230V models are supplied with one of the following plugs):

China

India

(NEMA 6-15P)

oIf the plug does not match the available receptacle, remove the plug and replace it with an approved plug of the suitable style.

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Original instructions

Chapter 2: Prerequisites

!Do not use any detachable power cord that is not adequately rated for the unit.

!Frequency must agree with the serial tag rating. Improper frequency will damage the compressor.

CAUSE THE CURRENT TO EXCEED THE RATING OF THE CIRCUIT BREAKER OR FUSE.ADDITIONAL APPLIANCES ON THE SAME CIRCUIT MAY

Location Requirements

The Freeze Dryer should be located in an area that provides an unobstructed flow of air around the cabinet. This air cools the refrigeration system. The refrigeration system draws air through the rear panel and exhausts it through the sides. A minimum of 3" must be allowed between the back and both sides of the Freeze Dryer and adjacent wall surfaces. Restriction of airflow during operation could adversely affect performance. The Triad Freeze Dryer must be placed on a work surface or table that will support over 400 lbs.

Refer to Appendix B: Freeze Dryer Dimensions for dimensional drawings.

Vacuum Pump Requirements

A vacuum pump must be provided by the user. A vacuum pump with a displacement of 98 liters per minute and 0.007 mbar ultimate pressure is adequate for most samples. The inlet fitting on the vacuum pump must be suitable for 3/4" ID vacuum hose, which is provided. It is recommended that the vacuum pump is equipped with an exhaust filter to minimize oil mist exhausting from the vacuum pump. The operating vacuum level may be set on the Freeze Dryer. The higher the vacuum set point, the more likely it is that oil mist will be exhausted.

Vacuum pumps should be equipped with a reverse IEC plug (included with 230V pumps purchased from Labconco). This will allow the vacuum pump to be plugged into the receptacle on the back panel of the freeze dryer.

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Original instructions

CHAPTER 3

GETTING STARTED

Now that the site for your Freeze Dryer is properly prepared, you are ready to unpack, inspect, install and test your Freeze Dryer. Read this chapter to learn how to:

Unpack and move your Freeze Dryer.

Set up your Freeze Dryer.

Connect the electrical supply source to your Freeze Dryer.

Properly exhaust your Freeze Dryer.

Safely use solvents with your Freeze Dryer.

!carton allows for lifting with a mechanical lift truck or hand truck. If you must lift the Freeze Dryer manually, use at least two (4) persons and follow safe lifting guidelines.The Triad Freeze Dryers weigh over 400 lbs (181 Kg). The

Unpacking Your Freeze Dryer

Carefully unpack your Freeze Dryer and inspect it for damage that may have occurred in transit. If your Freeze Dryer is damaged, notify the delivery carrier immediately and retain the entire shipment intact for inspection by the carrier.

AUTHORIZATION OF LABCONCO. UNAUTHORIZED RETURNS WILL NOT BE ACCEPTED.DO NOT RETURN GOODS WITHOUT THE PRIOR

The United States Interstate Commerce Commission rules require that claims be filed with the delivery carrier within fifteen (15) days of delivery.

8	Product Service 816-333-8811 or 1-800-522-7658

Original instructions

Chapter 3: Getting Started

YOU MUST FILE A CLAIM DIRECTLY WITH THE FREIGHT CARRIER. LABCONCO CORPORATION AND ITS DEALERS ARE NOT RESPONSIBLE FOR SHIPPING DAMAGE.

DO NOT DISCARD THE CARTON OR PACKING MATERIAL FOR YOUR FREEZE DRYER UNTIL YOU HAVE CHECKED

ALL OF THE COMPONENTS AND INSTALLED AND TESTED THE FREEZE DRYER.IF YOUR FREEZE DRYER WAS DAMAGED IN TRANSIT,

Freeze Dryer Components

Verify that the components listed below are present and undamaged.

Qty.	Part #	Description	Comments
1	1089005	User’s Manual	USB Flash Drive
1	Various	Power Cord	See parts list (Appendix A)
1	7373450	Vacuum Hose
2	1488800	Hose Clamp

If you did not receive one or more of the components listed for your Freeze Dryer, or if any of the components are damaged, contact Labconco Corporation immediately for further instructions.

Setting Up Your Freeze Dryer

After you verify receipt of the proper components, move your Freeze Dryer to the location where you want to install it. Then, follow the steps listed below.

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Labconco 794001010, 794001015, 794001030, 794001040, 794001050 Instruction Manual

Original instructions

Chapter 3: Getting Started

Component Identification

Sample Valves

USB Port

Touch Screen

On/Standby Button

LED Indicator

Vacuum Release

Backfill Port

Stoppering Control

Vacuum Pump Outlet

Power Inlet

Ethernet Port

End Point Detection

Vacuum Connection

Circuit Breaker Reset

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Original instructions

Chapter 3: Getting Started

Vacuum Pump Connection

A vacuum pump (as described in Chapter 2: Prerequisites) is required to operate your Freeze Dryer properly. The Freeze Dryer is equipped with a 3/4" ID vacuum hose for connecting the collector chamber to the vacuum pump.

VACUUM HOSE 3/4" ID

VACUUM

HOSE PUMP

CLAMP

!Makelevel. certain that the oil in the vacuum pump is at the proper

1.Place the vacuum pump near the Triad Freeze Dryer.

2.Remove protective caps from inlet and outlet ports.

3.Some vacuum pumps have inlet fittings that clamp to the pump. Place the centering ring with filter screen on the inlet fitting.

4.Place the hose barb fitting on top of the centering ring and secure with the clamp.

5.CHECK THE VACUUM PUMP OIL LEVEL.

	Fill the pump with oil so the level is between	Hose Barb
	the lines on the sight gauge on the end of the	Hose Barb
	the lines on the sight gauge on the end of the
	pump housing.

6.Attach one end of the vacuum hose to the port on the back of the Freeze Dryer and the other end to the inlet port of the vacuum pump with the hose clamps provided. If necessary, cut the hose to proper length to allow for gentle bends without kinks.

Inlet

Clamp

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Original instructions

Chapter 3: Getting Started

7.VERIFY THE VACUUM PUMP VOLTAGE SETTING AGREES WITH THE FREEZE DRYER VOLTAGE SHOWN ON THE SERIAL NUMBER LABEL. Reconfigure if necessary (see vacuum pump instructions).

8.Connect the vacuum pump power cord to the receptacle labeled “vacuum pump” on the back of the Freeze Dryer. Models rated for use on 230V have a reverse IEC receptacle for attaching the vacuum pump power cord.

9.If the vacuum pump has an ON/OFF switch, turn the switch ON. The vacuum pump will be controlled by the Freeze Dryer.

EXHAUST FILTER BE INSTALLED ON ROTORY VANE VACUUM PUMPS TO MINIMIZE OIL MIST EXITING THE PUMP. AN OIL RETURN KIT CAN ALSO BE USED IN

CONJUNCTION WITH THE EXHAUST FILTER TO RETURN TRAPPED OIL BACK TO THE VACUUM PUMP.IT IS HIGHLY RECOMMENDED THAT AN OIL MIST

Electrical Connection

Make sure that the outlet that you intend to use meets the voltage and amperage requirements listed on the serial tag of the Freeze Dryer. Plug the power cord into the receptacle on the back of the Freeze Dryer and plug the other end into a suitable power outlet. It will take approximately 90 seconds for the operating system to fully load.

Chemical Resistance of Freeze Dryer Components

The FreeZone Freeze Dry System is designed to be chemically resistant to most compounds that are commonly used in freeze drying processes. However, by necessity, the freeze dryer is comprised of a number of different materials, some of which may be attacked and degraded by certain chemicals. The degree of degradation is dependent on the concentration and exposure duration. Some of the major components of the Freeze Dryer that are susceptible to degradation are as follows:

12	Product Service 816-333-8811 or 1-800-522-7658

Original instructions

Chapter 3: Getting Started

Acids

Buffers

Solvents

Component

Material

<![if ! IE]>

<![endif]>Acetic Acid 20%

<![if ! IE]>

<![endif]>Formic Acid

<![if ! IE]>

<![endif]>Trifluoroacetic Acid (TFA)

<![if ! IE]>

<![endif]>Calcium Chloride

<![if ! IE]>

<![endif]>Sodium Phosphate

<![if ! IE]>

<![endif]>Acetone

<![if ! IE]>

<![endif]>Acetonittirle

<![if ! IE]>

<![endif]>Carbon Tetrochloride

<![if ! IE]>

<![endif]>Cyclohexane

<![if ! IE]>

<![endif]>Dioxane

<![if ! IE]>

<![endif]>Methyl t-Butyl Ether (BTBE)

<![if ! IE]>

<![endif]>Pyridine

Valve Stem

Acetal

Collector

Acrylic

Lid

Hoses,

Neoprene

Gaskets &

Valve

Bodies

Flask Top

Silicon

Rubber

Chamber &

Stainless

Fittings

Steel

C – Moderate degradation; Limited use

D – Severe degradation; infrequent use recommended; immediate thorough cleaning required.

Most common compounds used in freeze drying processes, if allowed to enter the vacuum pump, will degrade the oil and cause damage to the vacuum pump.

Sugars and proteins typically will have minimal negative effect on any of the materials of construction.

When using compounds in the Freeze Dryer that are hostile to the materials of construction, it is imperative the equipment is thoroughly cleaned after use.

Rubber and plastic components that have been exposed to damaging compounds should be removed and flushed with water.

The oil in the vacuum pump should be checked often. It must be changed if it is cloudy, shows particles or is discolored. The useful life of vacuum pump oil can be extended if the vacuum pump is operated for an extended period of time after a freeze dry run. This allows contaminants to be purged from the hot oil. This must be done with the inlet to the pump blocked off to prevent air from free flowing through the pump. If the pump is operated at an elevated vacuum level (> 10mbar), oil may be expelled from the pump and damage could occur.

Another way to extend the life of the vacuum pump is to install an optional secondary trap in the line between the Freeze Dryer and the vacuum pump. Contact Labconco for ordering information.

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Original instructions

Chapter 3: Getting Started

With prudent maintenance the Freeze Dryer will provide years of service. Warranty on the affected parts will be voided if maintenance has been obviously neglected. If you have questions about using specific compounds in the Freeze Dryer, contact Labconco Technical Service at 1-800-821-5525 or 816-333-8811 or e-mail: labconco@labconco.com.

		Solvent Safety Precautions
	!	Solvent Safety Precautions
	!	Solvents used in the Freeze Dryer may be flammable or
		hazardous to your health. Use extreme caution and keep
		sources of ignition away from the solvents. When using
		flammable or hazardous solvents, the vacuum pump must be
		vented to or operated inside a fume hood.
		Hazardous materials such as strong acids or bases, radioactive
		substances and volatile organics must be handled carefully and
		promptly cleaned up if spilled. If a sample is spilled in the
		collector chamber it must immediately be cleaned up.
		WARNING: The disposal of substances used in connection with
		this equipment may be governed by various Federal, State or
		local regulations. All users of this equipment are urged to
		become familiar with any regulations that apply in the user’s
		area concerning the dumping of waste materials in or upon
		water, land or air and to comply with such regulations.

14	Product Service 816-333-8811 or 1-800-522-7658

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