TM
Contents
Episcope
Skin Surface Microscope
Operating Instructions
Thank you for purchasing the Welch
operating and maintenance instructions found in this manual should be followed
to ensure many years of accurate and reliable service. Please read these instructions
thoroughly before using your new EpiScope Skin Surface Microscope.
Introduction to Skin Surface Microscopy..
Operating Instructions
Tables of Common Pigmented Lesions
Photographs of Common
Terminology
Care
Power Sources
Warranty
Technical Specifications
..................................................................................................
and Maintenance
A. Cleaning and Sterilization
B. Lamp Replacement Instructions
.................................................................................................................
...............................................................................................
Pigmented Lesions
.......................................................................................
and Accessories
..........................................................................................
Allyn EpiScope
...............................................................
.................................................................3-6
...........................................................................
Skin Surface Microscope. The
....................................................
.
1
2
7-8
19-20
21-22
22-23
.23
23
End Notes
Acknowledgments
......................................
...........................................................................
....................................................................................................
24
24
The use of in vivo skin surface microscopy as a means of more accurately
1,
2,3
assessing pigmented skin lesions has been advocated for over four
decades.
Recent studies have demonstrated the effectiveness of this method and new terms
have been developed to describe the unique images of the skin which are accen-
4,
tuated by skin surface
microscopy
5
.
One of these new terms is Epiluminescence
Microscopy (ELM) - the application of oil on the lesion while performing skin
surface microscopy.
It has been reported that “in vivo epiluminescence microscopy provides for a
more detailed inspection of the surface of pigmented skin lesions, and, by using
the oil immersion technique, which renders the epidermis translucent, opens a
new dimension of skin morphology by including the dermoepidermal junction
into the macroscopic evaluation of a
lesion."
6
Improvement in diagnostic accuracy when performing in vivo epiluminescence
318
microscopy in a study of
small pigmented skin lesions (that were diagnostically
equivocal when examined with the naked eye) was as follows: “for small nodular
melanomas from 50% to 70%; for superficial spreading melanoma in situ, from
to 80%; for invasive superficial spreading melanoma, from
early lentigo
maligna
and lentigo
maligna
melanoma, from
the diagnosis of pigmented Spitz nevi improved from
basal cell carcinomas from
60% to
90%.
7
"
64% to 90%; and for
67% to 88%. Conversely,
46% to 93% and of pigmented
46%
Included in this manual are tables of criteria for pattern analysis of pigmented lesions using epiluminescence microscopy, established by members of the
Department of Dermatology at the University of Vienna. This department, under
the chairmanship of Klaus Wolff, MD, has studied well over 7,000 pigmented
lesions. A selection of their photographs, magnified 10 times, (the same magnification as the Welch
Allyn EpiScope Skin
Surface Microscope) are included in this
manual, accompanied by descriptive legends. Where noted, some of the photographs
16x
were taken at
to accentuate the benefits of ELM. All the photographs were
taken with a WILD M650 (Wild Heerbrugg AG, Heerbrugg, Switzerland) binocular,
stereo microscope, equipped with an automatic Nikon F801 camera, mounted on
a side arm of the microscope and employing macro flash light illumination. All of
the photographs included in this manual are less than
6mm
in diameter, except
where noted in the legends. The diagnosis of the lesions included in this manual
were confirmed histologically.
1, 2, 3, *, 5, 6,
7
Refer to page 24 for End Notes