TURBOX® plus Protein Analyser
User’s Manual
CONTENTS Page
1 INTRODUCTION .......................................................................4
2 IDENTIFICATION OF MAIN PARTS OF TURBOX PLUS ..........5
3 SETTING UP .............................................................................6
3.1 Unpacking .....................................................................6
3.2 Location .........................................................................6
3.3 Selecting the Voltage .....................................................6
3.4 Connecting the Power Cable .........................................6
3.5 Paper Loading ...............................................................6
4 INSTRUMENT SPECIFICATIONS .............................................7
4.1 Nephelometer ................................................................7
4.2 Dimensions and Power Requirements ..........................7
5 SELF-TESTS .............................................................................7
6 OPERATION ..............................................................................7
6.1 Introduction ....................................................................7
6.2 Switching On .................................................................7
6.3 Assay Selection and Calibration ....................................8
6.4 Conducting an Assay ...................................................11
7 DATA OUTPUT ........................................................................13
7.1 Internal Printer .............................................................13
7.1.1 Printout during Measurements ....................................13
7.1.2 Printout of Measurement Summary .............................13
7.2 Serial Interface ............................................................14
8 ERROR MESSAGES ...............................................................15
8.1 Introduction ..................................................................15
8.2 Error Messages ...........................................................15
9 USER MAINTENANCE ............................................................17
9.1 Replacing the Ribbon Cassette ...................................17
9.2 Paper Loading .............................................................17
9.3 Software replacement .................................................17
9.4 Lithium battery .............................................................17
10 DECLARATION OF CONFORMITY .........................................17
11 WARRANTY .............................................................................17
APPENDIX 1: Assay Procedure .......................................................18
APPENDIX 2: Software replacement................................................19
1 INTRODUCTION
The Orion Diagnostica Turbox plus Protein Analyser system is intended for measurement
of specic serum and urine proteins important for medical diagnosis and patient monitoring.
The system consists of the Turbox plus Protein Analyser and associated assay kits.
The Turbox plus system is based on nephelometry, which utilises the light-scattering property
of antibody-antigen complexes (immunoprecipitates). The light source is a light-emitting
diode (LED). The intensity of the scattered light is related to the amount of complex formed,
and it is detected by opto-electronics.
Integral software converts the light-scattering units, LSU to concentration units of the protein
analysed. The results are automatically presented on a print-out.
Each assay kit contains of two Buffer solutions (Test Buffer, Blank Buffer), Reagent,
Calibrator and Calibration Card. The card incorporates a magnetic strip carrying encoded
lot-specic parameters which dene the overall assay calibration curve. This information is
transferred to Turbox plus by passing the card through the instrument’s card reader. Turbox
plus is then ready for use.
An extensive range of assays is available for use with the Turbox plus nephelometer.
Each assay comes complete with an instruction booklet giving full details of the assay
principle, performance and procedures involved. A current list of the range of assays
available can be obtained from your Orion Diagnostica Turbox plus distributor.
5
2 IDENTIFICATION OF MAIN PARTS OF TURBOX PLUS
Figure 1
Figure 2
7 Power ON/OFF Switch
8 Power Cord
9 Fuse
10 Serial Port
10
8
7
9
6
1
4
2
3
5
1 Card Reader Slot
2 Display
3 Keyboard
4 Measurement compartment
5 Lid of the measurement compartment
6 Printer compartment
3 SETTING UP
3.1 Unpacking
When unpacking your Turbox plus Protein Analyser, check you have received the following
items:
● Turbox plus Protein Analyser
● Power cable
● User’s Manual
● A printer roll
Check the instrument carefully. If there are signs of damage, notify your Turbox plus
distributor.
3.2 Location
The instrument should be placed indoors, on a clean, horizontal surface, and the following
points should be observed:
1. The ambient temperature must be between +5°C and +40°C.
2. The relative humidity must be less than 80 % with temperature ≤ +31°C,
decreasing linearly to 50 % relative humidity at +40°C.
3. Do not place the instrument in direct sunlight.
4. Do not place near X-ray machinery.
5. Store magnetic cards away from strong magnetic elds.
The instrument is convection cooled; the ventilation slots are on the underside of the casing.
When operating Turbox plus, ensure that the external circulation of air is not restricted and
that the ventilation slots are not obstructed.
3.3 Selecting the Voltage
The Turbox plus is delivered with 230 V selected. To change the voltage between 230 V and
110 V, remove the fuse cartridge from the back panel (see Fig. 2), place the desired voltage
in the lower right corner of the cartridge and reinstall the cartridge.
3.4 Connecting the Power Cable
Turbox plus is supplied with a power cable. At one end of the cable is an IEC plug which
should be inserted into the IEC socket at the rear of the instrument and the other end to a
grounded AC power source.
Place the Turbox plus instrument on such place where the power switch is easily reachable
and the power cable is not bent.
3.5 Paper Loading
The printer uses 57.5 ± 0.5 mm wide paper which may be obtained from your local Citizen
distributor or other ofce equipment supplier.
To load the paper:
● Open the printer cover by lifting it from the front
● cut the leading edge of the new paper roll so that it is parallel to the roll shaft
● align the paper so that it is straight and insert it into the paper inlet
● press <PAPER FEED> until the leading edge of the paper is able to pass the
paper cutter
● slide the paper through the paper cutter and close the printer cover