
Epson Stylus
®
 Pro 3880
Start Here
Start Here
Unpack
1  Make sure you have these items:
Printer
Power cord CD-ROM
User’s Guide
Turn On the Printer
1  Connect the power cable. (Do not connect the printer cable yet.)
2 Press the power button.
Ink cover
   After a minute, the ink cover is 
automatically released. 
Install Software for a USB Connection
Your printer software works with Windows® 7, Windows Vista®, XP Professional x64 Edition, 
Windows 
steps below to install the printer software. If you are using the Ethernet 
Chapter 1 of the User's Guide to configure the printer and install the software.
Macintosh
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2  Connect a USB cable. Use any open USB port on your computer. Make sure the Epson Stylus 
XP, and Macintosh® OS X 10.5.8 to 10.7. If you are using the USB interface, follow the 
®
 interface, follow the steps in 
Make sure your Macintosh and printer are turned on.
Pro 3880 is securely connected.
Ink cartridges
 Warning: The printer weighs about 43 pounds (20 kilograms) and should be lifted and moved 
by two people.
 Note: Do not open ink cartridge packages until you are ready to install the ink. Cartridges are 
vacuum packed to maintain reliability.
2   Remove all the packing materials and tape. 
Check carefully for all the tape inside and 
outside the printer. Save the box and packaging 
in case you need to ship the printer.
Limited WarrantyRear sheet guide
Install Ink Cartridges
1   Lift the ink cover. 
 Note: If the ink cover is locked, press the ink  
cover open button on the control panel to release it.
3  Insert the Epson Stylus Pro 3880 software CD.
2  Unpack the 9 ink cartridges and shake each one gently.
4 Double-click the Epson Stylus Pro 3880 icon.
Press the front 
cover to open it.
3   Open the top cover and remove the carriage retainer bracket. Then close the cover.
3   Install each cartridge in the correct slot for its color. The arrow mark should be on top and 
pointing into the printer.
Caution: Do not touch the green chip on top of the cartridge.
Arrow
Push each cartridge 
in until it clicks.
4  After you install all 9 ink cartridges, close the cover.
  Note: If you see the message that the installer has detected an older version of EpsonNet Config on 
your system, you must uninstall the old version before you can install the new one. To uninstall, drag 
the EpsonNet folder to the trash. Then reinstall your printer software.
5  Follow the on-screen instructions to install all the necessary software and manuals and register 
your printer.
6  Restart the Macintosh when prompted.
   The printer starts charging the ink. This takes 7 or 8 minutes. The LCD displays READY 
when charging is complete.
Caution: Do not turn off or unplug the printer while the power light is flashing and you see the 
message 
 Note: The first time you install ink cartridges, the printer uses some ink to charge the printing system, 
so print yields may be lower with the first cartridges. Subsequent ink cartridges will last for their full 
rated life.
CHARGING INK
 on the LCD. Also, do not lift the ink cover or load paper during the process.

Windows
   Make sure the Epson Stylus Pro 3880 is NOT CONNECTED to your computer.
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  Note: If you see a Found New Hardware screen, click Cancel and disconnect the USB cable. You 
can’t install your software that way.
2  Insert the Epson Stylus Pro 3880 software CD.
Load Paper
You can load paper in the auto sheet feeder, the rear manual feed slot, or the front manual feed slot. 
In the front or rear slot, load just one sheet at a time. Follow the instructions below to load paper 
in the auto sheet feeder or the rear manual slot. To load special media in the front slot, see the User’s  
Guide.
Note: Some paper types cannot be loaded in the auto sheet feeder. Check the User’s Guide to make sure 
you are using the correct paper path for your media.
Auto Sheet Feeder
   Flip open the paper guide and pull out its extensions to accommodate 
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your paper size.
2 Slide the left edge guide to the left. Then load one sheet of 
paper short edge first, glossy or brighter side face up, and slide 
the left edge guide against the paper. 
3 Gently guide the paper straight into the slot until it meets 
resistance, maintaining a constant pressure; after about 
3 seconds the printer will pull the paper into position.
  With Windows 7 and Windows Vista, if you see the AutoPlay window, click Run Setup.exe. 
When you see the User Account Control screen, click Ye s.
3 Click Install.
4  Connect a USB cable when prompted. Use any open USB port on your computer.
2   Press the front cover to release it and open the output tray.
4 Open the output tray and lift it into position. Make sure the 
arrow marks on the tray and inside the printer are aligned. 
Pull out the extensions as needed for your paper size.
3   Use both hands to pull out and extend the output tray, lifting 
it slightly as you pull. Make sure the arrow marks on the tray and inside the 
printer are aligned.
Any Questions?
Look here for answers:
User’s Guide
Instructions for using your printer. See Chapter 1 to install the printer software if you are connecting 
the printer on a network. You can also double-click the Epson Stylus Pro 3880 Guide desktop 
icon to view the on-screen User’s Guide.
5  Follow the on-screen instructions to install all the necessary software and manuals and register 
your printer.
6  When you’re done, click Exit and eject the CD.
4  Pull out the extensions as needed for your paper size.
5   Squeeze the left edge guide and slide it to the left. Then load your 
paper against the right edge guide short edge first, glossy or 
brighter side face up.
6   Squeeze the left edge guide and slide it against the paper.
On-screen Network Guide
Instructions for configuring the printer for a network.
On-screen help with your software
Select Help or ? when you’re using your software.
Epson Technical Support
Internet Support
Visit Epson’s support website at epson.com/support and select your product for solutions to 
common problems. You can download drivers and documentation, get FAQs and troubleshooting 
advice, or e-mail Epson with your questions.
SM
Epson Preferred
Call (888) 377-6611. Make sure you have your Epson Preferred Unit ID number. If you have any 
difficulty with this service, call (562) 276-1305. You can purchase a one- or two-year extended service 
plan through your Epson authorized reseller or from Epson.
 Protection Plan
Rear Manual Slot
  Attach the rear sheet guide by inserting the tabs as shown.
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Need Ink and Paper?
For the best prints, use genuine Epson ink and paper. You can purchase them from an Epson 
authorized reseller. To find the nearest reseller, call 800-GO-EPSON (800-463-7766). Or you 
can also purchase genuine Epson ink and paper online at www.epsonstore.com (U.S. sales) or  
www.epson.ca (Canadian sales).
Epson and Epson Stylus are registered trademarks and Epson Exceed Your Vision is a registered logomark of Seiko Epson 
Corporation. Epson Preferred is a service mark of Epson America, Inc. 
General Notice: Other product names used herein are for identification purposes only and may be trademarks of their respective 
owners. Epson disclaims any and all rights in those marks.
This information is subject to change without notice.
© 2011 Epson America, Inc. 10/11
Printed in USA  CPD-27472R1