Thermo Safety Cabinets MSC-Advantage User manual

Operating Instructions
Safety cabinet
MSC-Advantage™
Valid: 11.2006 / 50108599 A
Valid: 02.2007 / 50110565
Operating Instructions Safety Cabinet | MSC-Advantage
Inhaltsverzeichnis
These operating instructions are protected by copyright. Rights resulting thereof, particularly reprint, photomechanical or digital postprocessing or reproduction, even in part, are only allowed with the written consent of Thermo Electron LED GmbH. This regulation does not apply to reproductions for in-plant use.
Trademarks
MSC Advantage is a registered trademark of Thermo Fisher Scientific and of its subsidiary companies. All other trademarks mentioned in the operating instructions are the exclusive property of the respective manufacturers.
Thermo Electron LED GmbH Robert-Bosch-Straße 1 D - 63505 Langenselbold Germany
2
Operating Instructions Safety Cabinet | MSC-Advantage
Contents
1. General notes ......................................................................................... 6
1.1 Instruction of the operating personnel ........................................... 6
1.2 Applicability of the instructions ...................................................... 7
1.3 Warranty ........................................................................................ 7
1.4 Explanation of symbols ................................................................. 8
1.4.1 Symbols used in the operating instructions ............................. 8
1.4.2 Symbols on the device ............................................................. 9
1.5 Use of the device ......................................................................... 10
1.5.1 Correct use ............................................................................. 10
1.5.2 Incorrect use ........................................................................... 10
1.6 Standards and safety regulations ................................................ 11
2. Delivery ................................................................................................. 12
2.1 Standard components .................................................................. 12
2.2 Acceptance inspection ................................................................. 12
2.3 Transport security lock and device packaging ............................ 12
3. Installation ............................................................................................ 13
3.1 Ambient conditions ...................................................................... 13
3.2 Room ventilation .......................................................................... 14
3.3 Correct location............................................................................ 14
3.4 Installation in series ..................................................................... 14
3.5 Transport...................................................................................... 15
4. Description of the device .................................................................... 16
4.1 Overall view ................................................................................. 16
4.2 Safety system .............................................................................. 18
4.3 Filter system ................................................................................ 19
4.4 Operating and display elements .................................................. 20
4.5 Sample chamber access ............................................................. 21
4.6 Device interfaces ......................................................................... 22
4.7 Sample chamber illumination ...................................................... 24
4.8 UV lamp unit ................................................................................ 24
4.9 Working area ............................................................................... 24
5. Start-up.................................................................................................. 25
5.1 Initial operation ............................................................................ 25
5.2 Installing the device and accessories.......................................... 25
5.3 Unlocking the transport protection .............................................. 26
5.4 Levelling the cabinet .................................................................... 26
5.5 Power supply connection ............................................................ 27
5.6 RS 232 interface connection ....................................................... 28
5.7 Installation test ............................................................................. 29
6. Handling and control ........................................................................... 30
6.1 Operating panel ........................................................................... 30
6.1.1 Functional units ...................................................................... 30
6.1.2 Display during calibration routine ........................................... 31
6.1.3 Display during UV disinfection ............................................... 31
6.1.4 Failure messages ................................................................... 32
6.2 Device start-up ............................................................................. 32
6.3 Description of the operating modes ............................................ 33
7. Operation .............................................................................................. 35
7.1 Hygiene preparations for the sample chamber ........................... 35
7.2 Loading the sample chamber ...................................................... 35
7.3 Response to failure messages .................................................... 35
7.4 Work rules .................................................................................... 36
3
Operating Instructions Safety Cabinet | MSC-Advantage
Contents
8. Shut-down............................................................................................. 37
8.1 Interrupting an operation ............................................................. 37
8.2 Shutting the device down ............................................................ 37
9. Cleaning and decontamination .......................................................... 38
9.1 Decontamination procedure ........................................................ 38
9.2 Wipe/spray disinfection................................................................ 38
9.3 UV disinfection after a wipe/spray disinfection ........................... 40
9.3.1 UV disinfection using the integral UV lamp ............................ 40
9.3.2 UV disinfection using a mobile UV device (optional) ............. 40
9.3.3 Changing UV disinfection time ............................................... 40
9.4 Disinfection with formaldehyde ................................................... 41
9.5 Cleaning the exterior surfaces..................................................... 41
9.6 Cleaning the front window ........................................................... 41
9.7 Cleaning the floorpan .................................................................. 42
9.8 Cleaning the protective grid ......................................................... 42
10. Maintenance ......................................................................................... 43
10.1 Inspection .................................................................................... 43
10.2 Service ......................................................................................... 43
10.2.1 Sample chamber illumination ................................................. 44
10.2.2 Optional UV lamps.................................................................. 44
10.3 Retrofitting and repairs .............................................................. 44
11. Disposal ................................................................................................ 45
11.1 Disposal procedure ..................................................................... 45
12. Technical data ...................................................................................... 47
13. Device log ............................................................................................. 51
14. Certificate of decontamination ........................................................... 52
4
Operating Instructions Safety Cabinet | MSC-Advantage
Figures
Fig. 1 Device arrangement in the operating room .................. 14
Fig. 2 Lift points ....................................................................... 15
Fig. 3 Overall view ................................................................... 17
Fig. 4 Filter system with downflow and exhaust air filter ........ 19
Fig. 5 Operating and display elements ................................... 20
Fig. 6 Sample chamber opening ............................................. 21
Fig. 7 Supply interfaces ........................................................... 22
Fig. 8 UV lamp unit .................................................................. 24
Fig. 9 Working area on the workplate, armrests ..................... 24
Fig. 10 Stand installation ........................................................... 25
Fig. 11 Unlocking the transport protection ................................ 26
Fig. 12 RS 232 interface ............................................................ 28
Fig. 13 Operating panel I ........................................................... 30
Fig. 14 Operating panel II .......................................................... 31
Fig. 15 Display upon start-up .................................................... 32
Fig. 16 Sitting posture ............................................................... 36
Fig. 17 Protective grid segment ................................................ 42
Fig. 18 UV lamp replacement .................................................... 44
5
Operating Instructions Safety Cabinet | MSC-Advantage
1. General notes
The following are the addresses of the international Thermo Fisher Sales Organisations.
Postal address Germany
Thermo Electron LED GmbH Robert-Bosch-Straße 1 D - 63505 Langenselbold
Inquiries from Germany Phone
Sales 0800 1 536376 Service 0800 1 112110
Fax
Sales/Service 0800 1 112114
EMail
info.labequipment.de@thermofisher.com
Enquiries from Europe, Middle East and Africa Tel. + 49 (0) 6184 / 90-6940 Fax + 49 (0) 6184 / 90-7474 EMail
info.labequipment.de@thermofisher.com
Postal address USA
Thermo Fisher Scientific 275 Aiken Road Asheville, NC 28804 USA
Enquiries from North America Phone +1 800-879 7767 Fax +1 828-658 0363 EMail
info.labequipment.de@thermofisher.com
Enquiries from Latin America Phone +1 828-658 2711 Fax +1 828-645 9466 EMail
info.labequipment.de@thermofisher.com
Enquiries from Asia Pacific Phone +852-2711 3910 Fax +852-2711 3858 EMail
info.labequipment.de@thermofisher.com
1.1 Instruction of the operating personnel
These operating instructions describe the safety cabinet
MSC Advantage
and apply to the models MSC 1.2 and MSC 1.8.
The safety cabinet has been manufactured in keeping with the latest techno­logical developments and has been tested before delivery for its correct func­tion. It may, however, present potential hazards if it is not used according to the intended purpose or outside of operating parameters. Therefore, the following procedures must always be observed to prevent accidents:
The safety cabinet must be operated only by trained and authorized personnel.
For any operation of this device, the operator must prepare clear and con­cise written instructions in the language of the operating and cleaning per­sonnel based on these operating instructions, applicable safety data sheets, plant hygiene guidelines, and technical regulations, in particular:
which decontamination measures are to be applied for the cabinet and
accessories,
which protective measures apply while specific agents are used,
which measures are to be taken in the case of an accident.
Repairs to the device must be carried out only by trained and authorized expert personnel.
6
Operating Instructions Safety Cabinet | MSC-Advantage
1. General notes
1.2 Applicability of the instructions
The contents of the operating instructions are subject to change without further notice.
Concerning translations into foreign languages, the German version of these operating instructions is binding.
Keep these operating instructions close to the device so that safety instructions and important information are always accessible.
Should you encounter problems that are not detailed adequately in these ope­rating instructions, please contact Thermo Fisher Scientific immediately for your own safety.
1.3 Warranty
Thermo Fisher Scientific warrants the operational safety and functions of the safe­ty cabinet only under the condition that:
the device is operated and serviced exclusively in accordance with its intended purpose and as described in these operating instructions,
the device is not modified,
only original spare parts and accessories that have been approved by Thermo Fisher Scientific are used,
inspections and maintenance are performed at the specified intervals,
an installation test is performed prior to the initial operation of the device and that a repeat test is performed on the occasion of all inspections and repairs.
The warranty is valid from the date of delivery of the device to the operator.
7
Operating Instructions Safety Cabinet | MSC-Advantage
1. General notes
1.4 Explanation of symbols
1.4.1 Symbols used in the operating instructions
WARNING!
is used if non-observance may cause serious or even lethal injuries.
CAUTION!
is used if non-observance may cause medium to minor injuries or damage.
NOTE!
is used for hints and useful information.
RECYCLING!
Valuable raw materials can be reused.
Warning against electric shock.
8
1. General notes
1.4.2 Symbols on the device
Observe operating instructions (switchbox ceiling)
Warning against hand injuries (device side walls)
Biohazard (left front section of device)
Operating Instructions Safety Cabinet | MSC-Advantage
Checked safety (cover light dome)
Norme Française / NF - Postes de Sécurité Microbiologique
T5A note (sample chamber fusing)
RS 232 interface (upper side of plenum panel)
Armrest installation (right side of light dome)
9
Operating Instructions Safety Cabinet | MSC-Advantage
1. General notes
1.5 Use of the device
1.5.1 Correct use
The safety cabinet is a laboratory device for installation and operation in micro­biological and biotechnical laboratories of safety levels 1, 2, and 3. It has been designed as a Class II microbiological safety cabinet, in accordance with EN 12469 / 2000.
Depending on the hazard level of the agents involved, the operator must pre­pare in writing appropriate decontamination procedures for the device and the accessories used in the sample chamber.
Prior to the initial operation of the cabinet, the operator must perform an installation test. The test result must be documented by a test report. The cabinet must only be released for operation if it is in compliance with the operating parameters spe­cified by Thermo Fisher Scientific.
After any changes to the installation conditions and after any modification to the technical system, a repeat test must be performed and the test result must be documented by a test report that shows that all operating parameters are in com­pliance with those specified by Thermo Fisher Scientific.
1.5.2 Incorrect use
The safety cabinet must not be used in laboratories that do not comply with the requirements of safety levels 1, 2 or 3. The device must not be operated as a Class II safety cabinet if:
no repeat test is performed after changes to the installation conditions or after modifications to the technical system,
the alarm system of the device has issued a failure message and the cau­se for the failure has not been repaired.
The alarm system must not be tampered with or disabled. If alarm system com­ponents heve been removed or disabled for service or repairs, the device must only be released for operation if all alarm system components are functioning properly again.
The filters installed in the device are not capable of separating gaseous sub­stances. Therefore, never store or process gases or gas-releasing substances in the device:
who in quantity or concentration are toxic,
if a reaction with other substances may result in hazardous toxic concentrations or formation of toxic gases,
that may form combustible or explosive mixtures in combination with air.
10
Operating Instructions Safety Cabinet | MSC-Advantage
1. General notes
1.6 Standards and safety regulations
The device complies with the safety requirements of the following standards and directives:
NF 095 Rev3.2006 / NF - Postes de Sécurité Microbiologique
IEC 61010-1:2001
EN 61010-1:2001
EN 12469:2000
DIN EN 61326-1:2004-05
Low Voltage Directive 73/23 EWG
EMC Directive 89/336 EWG
11
Operating Instructions Safety Cabinet | MSC-Advantage
2. Delivery
2.1 Standard components
Delivery for the safety cabinet includes the following:
safety cabinet (without stand)
armrests
device documentation: – operating instructions – factory test report
Optional components and accessories are listed as separate items in the deli­very document.
2.2 Acceptance inspection
After the device has been delivered, immediately check the device:
for completeness,
for possible damage.
If the delivery is incomplete or if you detect any transport damage to the device, contact the forwarding agency and Thermo Fisher Scientific im­mediately.
2.3 Transport security lock and device packaging
A transport security lock protects the device counterweight during transport. Protective packagings protect the floorpan, the front window, and the workplate segments. To remove the transport security lock and the protective packagings, please refer to the enclosed installation instructions and to Sections 5.2 and 5.3 of these instructions.
12
Operating Instructions Safety Cabinet | MSC-Advantage
3. Installation
3.1 Ambient conditions
The operational safety and correct function of the device depend on the loca­tion where it is to be operated. The safety cabinet must be operated only at lo­cations that meet the ambient conditions listed below.
Location requirements:
The electrical system of the device has been designed for an operating height of up to 2000 m above sea level.
The mains power supply outlet should be out of casual reach to prevent ac­cidental shut-off. Ideally, the outlet should be installed above the safety cabinet. The outlet must be accessible to authorized personnel only. It constitutes, together with the power cable plug, the disconnection device for all poles.
The flooring of the location must be adequately strong and not flammable.
The stand must ensure a sufficient load-bearing capacity (twice the device weight).
The room in which the device is installed must be of adequate height. For devices that are not connected to an exhaust system, the distance between the exhaust air opening at the device ceiling and the room ceiling must be at least 200 mm (8 in).
The location must be equipped with an appropriate ventilation system (see Section 3.2.).
The temperature within the room must be between 15 °C and 40 °C (49 °F and 104 °F).
The relative humidity in the vicinity of the device must not exceed 90 %.
NOTE - Ambient conditions!
If ambient conditions vary from those descri­bed above, please contact Thermo Fisher Scientific for assistance in installing the device.
NOTE - Temporary storage!
If the device is stored only temporarily (up to four weeks), the ambient temperature may be between -20 °C and +60 °C (-4 °F and +140 °F) at a relative air humidity of up to 90 %. For lon­ger storage periods, the location requirements apply.
13
Operating Instructions Safety Cabinet | MSC-Advantage
3. Installation
3.2 Room ventilation
The room ventilation should preferably be a ventilation system that complies with the national requirements for the applica­tion.
The inlet air and exhaust air openings of the room ventilation must be located so that drafts are prevented from impairing the function of the safety cabinet air system.
3.3 Correct location
Choose a draft-free location where the safety cabinet does not interfere with the plant traffic. Fig. 1: This figure shows preferred locations for safety cabi­nets and unsuiable locations that are not in accordance with the safety requirements. Unsuitable locations: The locations [1], [2], and [3] are not suitable because they are exposed to drafts from windows and doors. Location [5] is unsuitable because it is within range of plant traffic and within the exhaust air range of a ventilation system [4]. Preferred locations: The locations [6], [7], and [8] are correct because they are in a draft-free section of the room and not exposed to plant traffic. A counterweight at the device backpanel moves synchronously with the vertical movement of the front window. To prevent the counterweight from jamming, the device backpanel should be as close to the wall as possible.
Fig. 1
Device arrangement in the
operating room
3.4 Installation in series
When several devices are to be installed in series, please ob­serve the following:
Make sure that vibrations cannot be transferred between adjacent devices.
Exterior surfaces of the cabinets must always be accessible for cleaning and disinfection.
14
3. Installation
3.5 Transport
Fig. 2: To prevent tilting, always transport the device using a
suitable carrier, even for a transport within a building, and se­parate it from the stand (see Section 5.2).
CAUTION – Lift points!
For transport, lift the device only at the lift points shown in Figure 2. Do not allow the weight of the cabinet to rest on the floorpan!
CAUTION – Crushing hazard!
Operating Instructions Safety Cabinet | MSC-Advantage
The weight of the front window is counterba­lanced by the counterweight (at the rear of the device). The device must not be transported unless the counterweight has been locked.
Install the four lockscrews (see Section 5.3).
Fig. 2
Lift points
15
Operating Instructions Safety Cabinet | MSC-Advantage
4. Description of the device
4.1 Overall view
Fig. 3: Plenum assembly [3] with plenum for downflow blower [18] and plenum for exhaust air blower [19]. The downflow filter and the exhaust air filter are installed immediately to the pertaining plenum. The exhaust air is dischar­ged to the exterior of the device through an opening [20]. The plenum assembly is concealed behind a cover [17].
Switchbox [2] with power supply unit and power supply cable [1]. The top of the device contains an RS 232 connection [22] for a PC and two fuse holders [21].
Light dome [4] for the sample chamber illumination unit, equipped with one fluorescent tube (model MSC 1.2) or two fluorescent tubes (model MSC 1.8). The optional, device-integral UV lamp is installed to the ceiling at the front section of the sample chamber.
Operating panel [5] with function keys and indicators.
Front window [7] with two handles [6].
Bushings [8] at the side panels (two on each side) into which media valves [10] can be installed. The covers must not be removed but only broken th­rough at the rupture joint.
Stand [9] (optional).
Workplate segments [12] with 2 armrests [13]. A one-pice workplate and special workplates are available as optional accessories.
Internal outlets [14] for the power supply of accessories (optionally, one of the outlets can be equipped with an adapter [16] for mobile UV devices).
Test hoses for the downflow unit [15] at the left side of the sample chamber and for the exhaust air unit [11] at the right side of the sample chamber.
NOTE – Test hoses!
Do not remove the caps of the two test hoses for checking downflow and exhaust air.
16
+ 37 hidden pages