Sanyo MDF-U500VXC, MLS-3781L, MDF-U74VC, MCO-19AIC, MCO-5AC User Manual

incubation preservation sterilization

Guide to Laboratory Equipment

Advanced Products and Technologies for
Life Science, Pharmaceutical, Biotechnology,
Clinical and Industrial Laboratories

www.sanyobiomedical.com

My Life. My Work. My Choice.

2 Guide to Laboratory Equipment www.sanyobiomedical.com

Guide to Laboratory Equipment

Table of Contents

Advanced Products and Technologies for
Life Science, Pharmaceutical, Biotechnology,
Clinical and Industrial Laboratories

My Life, My Work, My Choice

Welcome to SANYO Biomedical, a division of SANYO North America
Corporation. Headquartered in suburban Chicago, SANYO Biomedical oversees
marketing, sales, technical service and customer support for customers, sales
representatives, service providers and facility managers throughout North,
Central and South America.

Known throughout the world as a leader in consumer electronics and appli­ances, SANYO addresses global needs such as energy, food, housing, health
and information technology. For over forty years, SANYO Biomedical has
established a reputation as a premier manufacturer of precision biomedical and
laboratory equipment. As part of the worldwide SANYO brand we benefit from
our unique Vertical Component Integration
This gives us the most advanced technology, controls, construction and
performance attributes among many markets.

We combine ideas and innovations from our global network of industrial and
consumer products into a complete line of biomedical laboratory products.
Through this effort, we offer the industry’s most sophisticated refrigeration
compressor design and state-of-the-art electronics to ultra-low and cryogenic
freezers, refrigerators, incubators and environmental chambers.

SANYO Biomedical products are extensively tested to meet the toughest
quality standards in the world for performance, ergonomics and cost of
ownership. Every product we build is designed to minimize its carbon footprint
through energy savings and environmental stewardship. We understand that
our products are used in the most critical applications on the leading edge of
medicine, life science, pharmaceutical and agricultural research. We take this
responsibility seriously, which is why you can turn to SANYO Biomedical
with confidence.

™

approach to product development.

3 Intro to SANYO Biomedical
Solutions

39 Validation Services

incubation

9 CO2 Laboratory Incubators

14 CO2 and O2 Laboratory Incubators

17 Heated and Refrigeration Incubators

18 Plant Growth Chamber

preservation

24 V.I.P.™ Series Space Saving

-86°C Ultra-Low Freezers

25 Twin Guard Series -86°C
DualºCool Ultra-Low Freezers

28 MDF Series-86°C Ultra-Low
Freezers, Upright

29 MDF Series -86°C Ultra-Low
Freezers, Chest

30 -150°C Cryogenic Freezers

31 -30°C/35°C Biomedical Freezers

32 Laboratory Refrigerators

33 Pharmaceutical Refrigerators

34 Blood Bank Refrigerators

35 Biomedical Refrigerator
with Freezer Combination

36 General Purpose Refrigerators

36 Under-Counter Refrigerators
and Freezers

MDF-U5 00VXC

MCO-19AIC

MDF-U74VC

sterilization

38 Top-Loading Portable Autoclaves

MLS- 3781L

3

History of SANYO Biomedical
Equipment Development

Pharmaceutical refrigerator

Incubator

Medical autoclave -40°C freezer, MDF-400 Pharmaceutical refrigerators, MPR-110/210

Cooled incubator, MIR-150/250/550 -86°C ULT freezer, MDF-230

-30°C medical freezer, MDF-390 Upright medical freezer, MDF-300 -86°C ULT freezer, MDF-290

Blood Bank Refrigerator, MBR-390

-86°C upright ULT Freezer, MDF-380

Prefab refrigerator, MCU-1000

Cooling unit, MCU-5020

-30°C medical freezer, MDF-130

Compact blood bank refrigerator, MBR-105T PI controlled oven, MOV-102/202

Large pharmaceutical refrigerators, MPR-510/1010

Pharmaceutical refrigerator with -30°C freezer, MPR-211F Compact -86°C ULT freezer, MDF-190

P.I.D. controlled heated incubators, MIR160/260 Water jacketed CO

incubator, MCO-165

2

incubator, MCO-95

2

Dry heat sterilizer, MOV-102S/202S HEPA-filter unit, MBCR-717

Cleanroom unit, MBCR-2220C

Air jacketed CO

-135°C ULT freezer, MDF-2135

Pharmaceutical refrigerators, MPR-161D/311D

1971

1967

1966

1968

1970

1969

Core Technologies

SANYO core technologies, pat­ents and intellectual properties are
represented in every product line.
Core technologies apply to critical
components and processes such as
refrigeration compressors, micro­processor electronics and patented

™

V.I.P.

vacuum insulation panels
engineered to exact specifications
for important applications in the
life science, pharmaceutical, bio­technology, clinical and industrial
laboratories.

As a result, SANYO products operate
with dependability, safety, energy
efficiency and ergonomic sensitivity.
Look for these and other proprietary
technologies and patents on SANYO
Biomedical laboratory products.

1972

1974

1973

1976

1975

1978

1977

1979

1981

1980

1982

1983

1984

1985

1987

1986

Patented V.I.P.™ vacuum insulation panel freezers,
U.S. Patent No. 6260377

Twin Guard Series™ -86 DualºCool independent ultra-low temperature
refrigeration systems

Patented SafeCell™ UV contamination control,
U.S. Patent No. 6255103

inCu saFe™ germicidal effective copper-enriched
stainless steel incubator interior

P.I.D./R™ infrared CO2 system with rapid recovery,
dual sensor on Sterisonic

™

GxP Series (MCO-19AIC) only

Hydrogen Peroxide Vapor Sterilization,
new feature for the Sterisonic™ GxP Series (MCO-19AIC) only

™

Patented Direct Heat and Air Jacket

(DHA) incubator heating technology,

U.S. Patent No. 5519188

Active Background Contamination Control

™

cell culture environment

FDA clearance for in vitro fertilization, FDA K013703, October 30, 2001

SANYO-designed compressors specifically for laboratory refrigeration

SANYO-brand battery technology

SANYO-built electronic components

4 Guide to Laboratory Equipment www.sanyobiomedical.com

Bio-clean bench, MCV-9/13/16 Programmable cooled incubators, MIR-152/252/552

-86°C double-door upright ULT freezer, MDF-U581

Establishment of SANYO bio-soft laboratory, Tokyo plant Plant growth cabinet, MLR-350

Multi-gas incubator, MCO-175M

World’s lowest temperature freezer, (-152°C), MDF-1155(ATN)

Bench-top clean bench, MCV-711ATS Programmable high-temperature oven, MOV-313P

Plasma blast freezer, MDF-U460B Four-door pharmaceutical refrigerator with

-30°C freezer, MPR-411F/411FR ISO 9002 recognition

CFC-free refrigerants recognized by ASHRAE

(EPA Stratospheric Ozone Protection Award) ISO 9001 Introduction of world’s first vacuum insulated

-86°C freezer, MDF-U70V Pharmaceutical refrigerator, MPR-512/1012

ISO 14001 (environmental recognition) Introduction of inCu saFe

incubators

2

active background

™

contamination control in CO

revolutionary UV

™

incubators

2

Introduction of SafeCell

sterilization in CO

incubator,

2

™

GxP Series CO

™

freezers, MDF-U32V/U54VC

™

-86°C V.I.P.

Multi-gas incubator, MCO-18M

Introduction of -150°C freezer, MDF-C2156VANC

Introduction of large capacity reach-in

sterilization

2

O

2

incubator, MCO-80IC

2

CO

Introduction of Twin Guard Series

Introduction of Sterisonic

with H

-86 DualºCool ULT Freezer, MDF-U500VX

1991

1992

1988

1989

1990

1993

1994

1996

1995

Vertical Component Integration

™

1997

1999

1998

2000

2001

As a leader in consumer electronics, refrigeration, energy and
environmental products, SANYO offers a robust source of proven
technologies deployed throughout a range of biomedical and
medical research products.

Pioneering developments in consumer and industrial products are applied to all
SANYO products through the development model of Vertical Component Integration
Because many of our key component parts are designed and built by SANYO, we
offer only the very best, accurately matched components in each SANYO product.

As SANYO draws on vast corporate resources to develop laboratory products
to meet the needs of contemporary medical and scientific research, the SANYO
philosophy of Vertical Component Integration

™

is expressed in human-oriented,

easy-to-use ergonomic products.

Environmentally Friendly Technology

Always a leader in environmentally friendly technology, SANYO refrigerators use
commercially available HFC refrigerants and CFC-free insulation.

Compliance of RoHS, Restriction of Hazardous Substance,
on all units.

2005

2002

™

.

2004

2003

2007

2006

2008

2010

2009

GREEN

product

SANYO is committed to developing green technologies that
provide energy efficiency resulting in lower operational costs
with less impact on the environment.

5

Serving our Markets

SANYO Biomedical products are designed for the most demanding applications in clinical, pharmaceutical, life science,
biotechnology and research laboratory markets.

From incubation to preservation and sterilization, SANYO products continue to evolve from basic laboratory equipment
into the sophisticated yet user-friendly instruments used in critical cell management and leading-edge protocols. These
include gene and cell therapeutics for in vivo treatments, stem and embryonic cell growth and storage, regenerative
medicine, bio-manufacturing and more.

At the heart of this evolution are innovative applications of integrated electronics and digital acquisition systems developed
to control, monitor, document and validate the performance of our products as well as the safety of the work inside. As
multidisciplinary research reveals new solutions in cell manufacturing destined for clinical trials, SANYO is collaborating with
our customers to create products designed to satisfy strict third-party regulatory criteria such as FDA, AABB/ANRC,
GMPs, GLPs and more.

Thinking Green

SANYO has established a corporate-wide initiative to emphasize the company’s commitment to energy conservation and
environmental integration. For SANYO, thinking green is a threefold approach to environmental, energy and lifestyle consider­ations. Here, SANYO is redefining conventional ideas and taking advantage of the company’s expansive technological
resources to propose environmentally friendly solutions.

Our commitment to the environment is illustrated by the company’s early and aggressive efforts to revamp and redesign
the refrigeration systems upon which so many of our products depend. We were among the first to adopt new, environmentally
safe, non-ozone depleting refrigerants without compromising performance. We were the first ultra-low freezer manufacturer
to use non-CFC R508 refrigerants, today recognized as the worldwide industry standard and now readily available as a
non-proprietary recharge to refrigeration service professionals on the open market. Other SANYO Biomedical refrigerants
such as R134a and R410a (Puron

SANYO Biomedical cabinets are insulated with high-performance HCFC-free insulation and new composite insulation
techniques to minimize energy consumption and lower operating costs. Beyond highly competitive first costs, SANYO
Biomedical ultra-low freezers demonstrate the lowest operating costs per cu.ft. (liter) in the worldwide market.

Superior insulation technologies enable our exclusive High-Density Storage
of useable storage volume per sq.ft. of floor space in the industry, maximizing laboratory space efficiency and reducing
overall costs of ownership.

®

), are safe and sourced on the open market as well.

™

valuation to offer the most favorable ratio

6 Guide to Laboratory Equipment www.sanyobiomedical.com

incubation

SANYO
Incubation

World Class Design. SANYO designs and manufactures a range of CO2 and
multi-gas incubators, refrigerated and heated environmental chambers to
meet a variety of application and user needs.

7

SANYO Incubators

SANYO designs and manufactures a range
of CO2, multi-gas, heated, and refrigerated
incubators to meet a variety of application
and user needs.

CO

Laboratory Incubators

2

MCO-5AC
MCO-18AC(UV)
MCO-36AC(UV)
MCO-19AIC
MCO-38AIC
MCO-19AIC(UV)
MCO-38AIC(UV)
MCO-19AIC(UVH)
MCO-38AIC(UVH)
MCO-20AIC
MCO-40AIC
MCO-80IC

CO2/O2 Laboratory Incubators

MCO-5M
MCO-5M(UV)
MCO-18M
MCO-36M
MCO-18M(UV)
MCO-36M(UV)

Heated and Refrigerated
Incubators

MIR-162
MIR-262
MIR-154
MIR-254
MIR-554

Plant Growth Chamber

MLR-351H

Relative Humidity

A removable water pan combined
with an independent heater at the base
of the incubator provides an efficient,
cost-effective method for maintaining
elevated humidity levels. The humidify­ing pan can be easily removed and a
water level sensor provides an easy

maintenance system.

Preventative
Contamination Control

SANYO’s inCu saFe™ and SafeCell™
UV work in combination to provide
the most effective protection against
contamination during culturing without
downtime or affecting cultures.

InCu saFe™ Copper
Stainless Steel Alloy

InCu saFe™ copper-enriched stainless
steel alloy combines the corrosion re­sistance and durability of stainless steel
with the germicidal properties of copper.
The inCu saFe

™

walls and shelves signifi­cantly reduce the risk of contamination
developing on internal surfaces.

H2O2 Sterilization

The unique Sterisonic™ GxP H2O2
sterilization system limits downtime to
less than three hours when total cham­ber sterilization is desired. All interior
components and CO
sterilized in situ; no need for removal
and autoclaving.

sampling loop are

2

CO2 Control

SANYO proprietary singlebeam, dual
detector infrared (IR2) CO
ers precise CO

control, quick recovery

2

sensor deliv-

2

following door openings, and auto
sampling with no moving parts.

SafeCell™ UV

(U.S. Patent 6255103)

SANYO’s SafeCell™ UV system with
programmable, ozone-free UV lamp
sterilizes the chamber air and water
in the humidifying pan.

The UV lamp is completely isolated from the cell cultures
and unlike other methods, the SafeCell™ UV system does
not trap contaminants inside the incubator or require the
temporary removal of critical components.

8 Guide to Laboratory Equipment

SANYO
Sterisonic™

H2O2 sterilization vs. high heat sterilization

2 Hours

= Uptime (Hours)

MCO-18AC

Brand X

=

Downtime (Hours)

14 Hours

MCO-80IC

MCO-38AIC(UV)

MCO-20AIC

CO2 Laboratory Incubators

All SANYO CO2 incubators feature patented Direct Heat and Air Jacket™ temperature control for accurate, uniform temperature control and inCu
saFe™ for continuous contamination control. SANYO laboratory CO2 incubators feature selected SafeCell™ UV with exclusive, patented Active
Background Contamination Control™.

CO2 Laboratory Incubators

Model Number

MCO- 5AC

MC O-18AC /

MCO-18AC(UV)

MCO-36AC/

MCO-36AC(UV)

MC O-19AI C

MCO-38AIC

MCO-19AIC(UV)

MCO-38AIC(UV)

MCO-19AIC(UVH)

MCO-38AIC(UVH)

MCO-20AIC

MCO-40AIC

MCO-80IC

Volume

(cu.ft.)

49 L

164 L

11. 6

328 L

170 L

12.0

340 L

170 L

12.0

340 L

170 L

12.0

340 L

215 L

15.2

430 L

30.1

851 L

Exterior Dimensions

1.7

5.8

6.0

6.0

6.0

7.6

18.9" x 21.6" x 22.6 "

480 x 548 x 575 mm

24.4" x 27.0" x 35.4"

620 x 686 x 900 mm

24.4" x 27.0" x 70.8"

620 x 686 x 180 0 mm

24.4" x 27.9" x 35.4"

620 x 710 x 90 0 mm

24.4" x 27.9" x 70.8 "

620 x 710 x 180 0 mm

24.4" x 27.9" x 35.4"

620 x 710 x 90 0 mm

24.4" x 27.9" x 70.8 "

620 x 710 x 180 0 mm

24.4" x 27.9" x 35.4"

620 x 710 x 90 0 mm

24.4" x 27.9" x 70.8 "

620 x 710 x 180 0 mm

30.3" x 27.9" x 35.4"

770 x 710 x 90 0 mm

30.3" x 27.9" x 70.8"

770 x 710 x 1800 mm

38.8" x 33.6" x 80.3"

986 x 853 x 2040 mm

(w x f-b x h) Contamination Control CO2 Control Chamber

Optional SafeCell UV with ultraviolet light,

inCu saFe copper-enriched stainless steel interior

inCu saFe copper-enriched

stainless steel interior

(optional UV )

inCu saFe copper-enriched

stainless steel interior

SafeCell UV with ultraviolet light, inCu saFe

copper-enriched stainless steel interior

SafeCell UV with ultraviolet light, inCu saFe

copper-enriched stainless steel interior,

SafeCell UV with ultraviolet light, inCu saFe

copper-enriched stainless steel interior

Optional SafeCell UV with ultraviolet light,

inCu saFe copper-enriched stainless steel interior

H

2O2

sterilization

thermal

conductivity

thermal

conductivity

infrared with

P.I.D./ R recover y

infrared with

P.I.D./ R recover y

infrared with

P.I.D./ R recover y

infrared with

P.I.D./ R recover y

infrared with

P.I.D./ R recover y

Combination H2O2 Sterilization, SafeCell™ UV Technology and inCu saFe™ interior construction for contamination control and no culturing downtime.

InCu saFe™ Interior

Copper alloy stainless steel plenums,
shelves and brackets extend contami­nation control to the chamber interior.
Superior contamination control with an
anti-bacterial copper alloy stainless steel
interior provides germicidal protection
and eliminates molds, spores and other
contaminating spills, kills mycoplasma and
provides a noncorrosive environment.

Sterisonic™ GxP Series
with H2O2 Sterilization

The unique Sterisonic™ GxP H2O2
sterilization system limits downtime
to less than three hours when total
chamber sterilization with verification

SafeCell™ UV
Contamination Control

Narrow bandwidth ultraviolet steriliza­tion in situ to eliminate air and water
pan contamination without downtime.
SANYO SafeCell
to protect against contamination during
normal operation by combining the
passive resistance of copper-enriched
stainless steel with UV decontamination
of circulated, humidified air. Independent
testing confirms that exposure to ultra­violet light at 253.7nm and heat steriliza­tion at +90°C and +140°C are equally
effective in decontaminating an incuba­tor interior chamber against organisms
selected for testing.

™

UV system continues

CO2 Control Options

Available with high precision, quick
recovery infrared or thermal CO

Direct Heat and
Air Jacket™ Control

Patented, radiant-wall heating micro­processor controlled in three zones to
maintain uniformity and optimum humid­ity. Unlike traditional water jacket units,
the sealed air jacket and foam insulation
maintains a uniform temperature and
quick temperature recovery after door
openings. Air jacket technology requires
little maintenance and provides a light­weight unit for easier relocation
or repositioning for cleaning.

is desired.

P.I.D./R™ Control Sophistication

Proportional, integral and derivative
infrared CO
ery and prevents overshoot.

control accelerates recov-

2

single

single

dual

single

dual

single

dual

single

dual

single

dual

single

Voltage, Power

Connection

115 V

NEMA 5 -15

115 V

NEMA 5 -15

115 V

NEMA 5 -15

115 V

NEMA 5 -15

115 V

NEMA 5 -15

115 V

NEMA 5 -20

sensor.

2

9

MCO-18AC

MCO-36AC

MCO-18AC(UV)

MCO-36AC(UV)

CytoGROW™ GLP Series Cell Culture CO2 Incubator

Ideal for research and clinical microbiology, the SANYO CytoGROW™ GLP CO2 incubator offers
a high-performance solution for mainstream cell culture applications in the research and clinical
environment where precise control and contamination resistance is critical.

The CytoGROW™ GLP Series Advantage At-A-Glance

System Feature Competitors SANYO Benefit

™

Contamination
Resistance In Situ

Air and Water
Decontamination In Situ

Cabinet
Construction

Active Background

Contamination Control

with inCu saFe

enriched stainless

SafeCell

Ease-of-use Direct Heat

and Air Jacket

™

steel interior

™

UV Protection

(Optional)

™

copper-

design

Stainless steel InCu saFe

™

Not available SafeCell™ UV protection located safely below the interior base destroys airborne

Composite

direct heat or

water jacket

steel does not offer a similar latent protection.

contaminants as they pass over the humidity reservoir surface. Pathogens introduced

during door openings are ultimately removed.

The SANYO combination of inCu saFe™ and SafeCell™ UV eliminates the need for time-

consuming, disruptive heat decontamination. SANYO minimizes downtime for total

cleaning when required, with the benefit of continuous, preventive contamination

control during normal operation.

The SA NYO Cy toGROW

of a water-jacketed cabinet without the inconvenience. SANYO uses sensitivity

to ambient temperatures to permit the microprocessor-controlled, multi -zone SA NYO

Direct Heat and Air Jacket

maximum temperature control and uniformity from three independent heating

zones on all sides.

forms integral germicidal barrier against airborne contaminants; stainless

™

GLP series cabinet provides the stability and uniformity

™

system to work most efficiently. SANYO maintains

Product Overview

CytoGROW™ GLP series is part of
the SANYO MCO incubator product
group that share proven control,
construction and functional performance
attributes. This relational product line
extends the most sophisticated SANYO
operating systems, offering more range
of application and better continuity
among users in the research and
clinical community.

10 Guide to Laboratory Equipment www.sanyobiomedical.com

The 6 cu.ft. (170 liter) CytoGROW™ GLP
cabinet integrates SANYO’s proven
package of control, heating, gas control
and construction features essential to all
incubators. This design approach fulfills a
broad range of common applications.

Additionally, the standard CytoGROW
GLP cabinet can be enhanced with a
selection of options and accessories to
meet specific end user needs, offering
the industry’s most flexible investment
option for current and future incubator
needs.

MC O-18AC

Ideal for Research and
Clinical Microbiology

Biotech Research and Production•
Hospitals and Clinics•
Public Health•
Medical Research•

™

Quality Control•

SANYO Design and Construction

InCu saFe™ Interior Surfaces
for Germicidal Protection

The CytoGROW™ GLP incubators
incorporate inCu saFe
stainless steel alloy interior surfaces
within a comprehensive design created
to eliminate contamination sources and
to mitigate the effect of airborne contam­inants introduced through normal use.

Selected to provide natural germicidal •
protection without rust or corrosion,
inCu saFe

™

expresses a natural ger­micidal attribute to inhibit the growth
of molds, fungi, mycoplasma and
bacteria.

All interior components, including •
the air management plenum, shelf
supports, humidity pan and blower
wheel assembly remove easily for
autoclaving; no tools required.

When components are removed, •
all interior surfaces are exposed for
conventional wipe down.

Large rounded corners and electropol-•
ished surfaces are easy to clean.

™

copper-enriched

Effectiveness of inCu saFe™ - Mycoplasma Survival Results

Mycoplasma
Strain

Mycoplasma
fermentans PG18

Mycoplasma
orale CH19299

Mycoplasma
arginini G230

Mycoplasma
hominis PG21

Chart summarizes test results with four strains of mycoplasma. Results demonstrate how SANYO inCu saFe™
copper-enriched stainless steel alloy offers germicidal properties of conventional C1100 copper, while maintaining
both corrosion-proof and discoloration-resistant properties of conventional Type 304 stainless steel.
Detailed test results are available from SANYO.

Ergonomic Cabinet Design

With a reversible outer door, a single
SANYO incubator offers the industry's
most flexible installation options avail­able in either single or dual (stacked)
cabinet configurations.

The low profile cabinet with door-•
mounted control panel permits easy
access and display viewing.

Cabinet knock-outs are predrilled •
and tapped to eliminate drilling and
to simplify remounting of the field
reversible door.

The outer door heater cable is •
easily switched if a reverse opening
is required.

ErgoStack™ Low Profile Design

The CytoGROW™ GLP cabinet is
designed for stacking, allowing one
unit to be positioned on top of another,
doubling interior volume without
additional floor space.

The low profile cabinet with •
door-mounted control panel permits
easy access and display viewing.

The combination of stacking and •
reversible doors offers the industry's
most flexible installation options.

An optional roller base is recom-•
mended for stacked installations
to permit mobility if required;
see Accessories.

Negative

Control

no survival survival no survival no survival

no survival survival no survival no survival

no survival survival no survival no survival

no survival survival no survival no survival

MCO-36AC(UV)

Conventional Type

304 Stainless Steel

The outer door closes against a •
soft, easily cleaned magnetic gasket
designed to eliminate ambient air
shear across the glass inner door,
minimizing condensation.

The outer door includes a universal •
finger grip at each side.

A door ajar alarm provides an audible •
and visual warning if the outer door
is left open.

Pass-through ports accommodate •
probes or instrumentation leads as
required for specialized cell culture pro­tocols. Each chamber includes a port
positioned in the interior, upper-left rear
wall, with dual silicone (non-VOC) stop­pers inside and outside the cabinet for
added protection.

SANYO

InCu saFe

™

Conventional

Copper C1100

11

MCO-19AIC
MCO-19AIC(UV)
MCO-19AIC(UVH)

Sterisonic™GxP Series Cell Culture CO2 Incubators

The industry’s most complete cell culture solution for highly
regulated applications or conventional incubation.

The SANYO Sterisonic™ GxP incubator
is designed for a wide array of demand­ing and highly regulated applications in
the biomedical, pharmaceutical, medical
research and clinical laboratory.

Representing years of research, devel­opment and component testing, the
Sterisonic

™

GxP incorporates a collec­tive of mutually functional systems and
design attributes to offer a holistic solu­tion to cell culture protocols, from the
most sophisticated to more familiar and
conventional processes. These include
but are not limited to:

Stem cell research•
Autologous tissue regeneration •

& regenerative medicine

• In vitro fertilization
Genomic and proteomic expression•
Esoteric plant and amphibian cell culture•
Genomic and proteomic expression•
Hypersensitive and transgenic •

cell culture
Low media volume •

microplate work

PREP: 15 min.

Reposition shelves, humidity
pan and plenum inside
SANYO chamber. Interior
surfaces are exposed.

Sterisonic™ GxP H202

Sterilization Cycle

(3 Hours, total)

Sterisonic™ GxP Design

Elevated humidity, low water level •
warning. To avoid cell culture desicca-

tion, the SANYO Sterisonic
CO

incubator maintains ~95%

2

RH at 37°C.

Ergonomic cabinet design• . With
reversible inner and outer doors, a
single SANYO incubator offers the
industry’s most flexible installation
options.

Field reversible door. • The field-
reversible door allows universal
installation using the left-hand hinge
(standard) or a right-hand hinge
modification.

Inner door and gasket.• The
inner design is critical to successful
contamination control technique.

Start Cycle: 30 min.

Press H2O2 start button.
Chamber warms to 45˚C.

™

GxP

SANYO Sterisonic™ GxP Model MCO-19AIC(UVH)
with integrated H2O2 sterilization system.

Sterilize: 7 min.

SANYO H2O2 atomizer creates vapor which is
circulated throughout chamber by interior blower.

Resolve: 90 min.

UV lamp glows for 90 minutes,
reducing H

to harmless water droplets.

2O2

Finish.

Shelves, humidity pan and plenum
are returned to operating position.

Elapsed Time:

Conventional High Heat

Decontamination

15 min. 30 min. 45 min. 1 2

(24 Hours, total)

PREP: 15 min.

Remove interior components
sensitive to high heat.

12 Guide to Laboratory Equipment www.sanyobiomedical.com

Start Cycle: 90 min.

Interior chamber elevates to high heat.

3

Sterilize: 14 hours

Interior chamber remains at high heat.

4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24

Control and Monitoring

The Sterisonic•
tion center includes an intuitive pop-up
menu, high resolution LCD for inputs,
outputs and performance at-a-glance.

Multi-point data logging offers push-•
button graphical display. An optional PC
interface permits remote transmission
for GMP/GLP protocols as required.

Precise P.I.D. logic controls and adjusts •
to all temperature and CO
and alarm parameters.

™

GxP control and informa-

setpoints

2

Sterilization and Decontamination

The unique Sterisonic•
sterilization system limits downtime
to less than three hours when total
chamber sterilization with verification
is desired.

All interior components and CO•
sampling loop are sterilized in situ; no
need for removal and autoclaving.

Continuous Active Background •
Contamination Control
contamination while cell culture
protocols are in process.

™

GxP H2O2

™

fights

2

CO2 Control

SANYO proprietary single-beam, dual •
detector infrared (IR2) CO
delivers precise CO

sensor

2

control, quick

2

recovery following door openings, and
auto sampling with no moving parts.

Temperature and
Humidity Control

The patented Direct Heat and Air•
conditioning system manages setpoint
temperature through multiple, variable
warming points under microprocessor
control.

The humidity pan is easy to fill, easy •
to clean; the automatic optical sensor
advises of low water level.

™

™

The Sterisonic
controller with LCD graphical display simplifies all
incubator functions. Stable temperature and humidity
conditions are achieved through a combination of
performance systems supervised by the controller
complete with alarm, programming, calibration and
diagnostic protocols.

GxP integrated microprocessor

A continuous Active Background Contamination
Control™ process eliminates contamination
without downtime. At the base of the plenum
an isolated beam of high intensity, ozone-free
ultraviolet light destroys contaminants in the
air and in the humidity water reservoir, away
from active cell cultures.

Finish.

Incubator must cool from high heat
temperatures to near ambient.

The patented Direct Heat and Air Jacket™ heating
system distributes proportional energy to the interior
chamber through a natural convection air jacket
surrounded by a high-density insulation to protect
against ambient temperature fluctuations.

13

MCO-80IC

CO2 recovery after a 60 second door opening

for the SANYO MCO-80IC

5%

4%

3%

2%

1%

10 min. 20 min.

CO2 recovery after a 60 second door opening

for the SANYO MCO-80IC

CO

2

recovery after a 60 second door opening

for the competitor

Temperature Recovery

5%

4%

3%

2%

1%

5%

4%

3%

2%

1%

10 min. 20 min.

10 min. 20 min.

10 min. 20 min.

Reach-In CO2 Incubator

SANYO’s large capacity, reach-in CO2 incubator
has the capacity and flexibility to grow with
your culturing needs while providing a precise
and repeatable temperature, humidity
and CO

The MCO-80IC is ideal for culturing large
volumes of patient samples, performing
short-term studies, and working with
large volume cell culture apparatus. It
includes SANYO’s exclusive incubator
technologies such as inCu saFe
ors, UV decontamination option, infrared
(IR) CO
features exceptionally low CO
consumption.

environment.

2

™

interi-

sensor with P.I.D. control, and

2

gas

2

Usability

30.1 cu.ft. (851L) large capacity •
cabinet allows flexibility in usage.

Cabinet will accommodate a roller •
bottle apparatus, 5 bottles wide x 7
bottles high (requires mounting
ramp kit).

Full view, double paned glass door •
allows easy observation of cultured
samples (glass tinting is also optional).

Large LED digital display and keypad •
for greater visibility and ease of
set-up.

Superior CO2 and
Temperature Control

IR CO•

sensor with P.I.D. microproces-

2

sor control and forced air circulation
system delivers fast CO
characteristics.

Exceptionally low CO•
tion rates, less than half of similar
competitive units.

P.I.D. temperature control with •
deviation of +/- 0.1°C.

14 Guide to Laboratory Equipment www.sanyobiomedical.com

recovery

2

gas consump-

2

MCO-80IC reach-in CO2 incubator.

SANYO MCO-80IC Competitor

Faster CO2 Recovery and Lower CO2 Consumption. SANYO’s large capacity reach-in incubator was designed
specifically for critical applications in pharmaceutical, biotechnology and clinical investigation.

CO2 recovery after a 60 second door opening

for the SANYO MCO-80IC

Temperature Recovery

5%

4%

3%

2%

1%

37°C

36°C

35°C

34°C

33°C

10 min. 20 min.

10 min. 20 min.

UV Sterilization - Light Indicator

Open Door Indicator

Water Reservoir
Level Indicator

Heater On Indicator CO

Inject Indicator

2

Setpoint - Set Temperature and CO

Calibration - Calibrate air temperature and CO

Optional Built-in CO

2

2

Tank Switchover System

2

Alarm, Buzzer
Silence

Secondary Over
Temp. Indicator

Over Temp. Safety Shut off Adjustment

Anti-Contamination Measures

Interior, plenums and shelving •
constructed of SANYO’s exclusive
inCu saFe
enriched stainless steel.

Optional UV sterilization system •
for humidity reservoir.

Extra heaters positioned on the •
outer glass door to eliminate
condensation.

™

, germicidal, copper-

Display

CO

2

Temperature Display

High Humidity Mode Indicator

Scroll Programming Buttons

Horizontal Laminar
Airflow System

SANYO’s reach-in incubator’s cross­shelf directed air flow system promotes
optimum temperature uniformity
throughout the chamber and contributes
to quick temperature recovery after door
openings. Utilizing SANYO’s exclusive
inCu saFe
perforated side plenums helps minimize
contamination concerns and direct posi­tive and negative pressure air flow.

Horizontal airflow maintains accurate temperature
and CO2 control and uniformity at all shelf levels,
top-to-bottom, front-to-back.

Perforated sidewall panels right (pressure) and left
(negative pressure) assure a positive, gentle airflow
from right to left.

™

chamber material in the

Optional UV Sterilization
and Humidity Selection

SANYO’s patented and laboratory
proven Safe Cell UV
is employed to sterilize the humidifying
water reservoir and help eliminate
contamination concerns. The unit can
be set to both nominal and high
humidity setpoints.

Humidity reservoir heaters are located
on the outside walls of the reservoir
and are not as susceptible to corrosion
and scaling from water as competitive
systems are. An optional autofill second­ary tank (Model MCO-80AS) system is
also available to ensure continuous
water supply to the humidity reservoir.

This system employs a large tank
(4.8 gal./18 L), with electronic water level
sensor and autofill solenoid valve.

™

sterilization system

Humidified air minimizes potential for cell culture
media desiccation.

™

Optional SafeCell

UV sterilization system provides

decontamination of the humidity reservoir.

Recovery after a 30 second door opening for the
Sanyo MCO-80IC.

15

CO2/O2 Laboratory Incubators

SANYO models MCO-5M/18M/36M series CO2/O2 incubators employ multiple sensor technologies to achieve in vitro simulation of the in vivo
environment. MCO Series CO2 and CO2/O2 incubators have received U.S. Food and Drug Administration 510(k) clearance for in vitro fertilization
applications in accordance with the FDA Safe Medical Devices Act of 1990 and the Medical Device Amendments of 1992.*

CO2/O2 Laboratory Incubators

Model Number

MCO-5M

MC O-18M

MCO-36M

Volume

(cu.ft.)

49 L

170 L

12.0

340 L

Exterior Dimensions

1.7

6.0

480 x 548 x 575 mm

24.4" x 28.0" x 35.4"

620 x 710 x 90 0 mm

24.4" x 28.0" x 70.8 "

620 x 710 x 180 0 mm

(w x f-b x h) Contamination Control CO2 Control O2 Control

18.9" x 21.6" x 22.6 "

inCu saFe copper-enriched

stainless steel interior,

optional SafeCell UV with

ultraviolet light.

For below ambient or enriched (above ambient) oxygen levels in addition to CO2 control.

Infrared CO2 Sensor

Precise CO2 control, fast response to
door openings. The SANYO CO
sor monitors and controls CO
over a range of 0% to 20%, with control
of ±0.15%.

Inner Doors

Multiple chamber inner doors minimize
loss of balanced interior atmosphere dur­ing routine door openings (available on
selected models).

Professional Cell Culture
Multi-Gas Incubator:

Continuous contamination •
control with inCu saFe
interior and SafeCell
technologies.

P.I.D. controls for fast •
recovery of temperature,
CO

and O2 levels.

2

Fast humidity level recovery •
by N

gas bubbler.

2

MC O-18 M

thermal conductivity

P.I.D./ R recover y

IR sen-

2

level(s)

2

™

™

UV

Zirconia sensor with

infrared with

P.I.D./ R recover y

Zirconia O2 Control

Non-depleting design for precise O2
control with fast response to door
openings. The maintenance-free zirconia
solid-state electrolyte sensor has a high
degree of precision, a long service life
and does not require fine adjustment.
Through accurate determination of the
chamber O

level the microprocessor

2

injects either nitrogen gas or oxygen
as required.

P.I.D./R™ Control Sophistication

Proportional, integral and derivative infra­red CO
prevents overshoot.

*

Regulation Number: 21 CFR 884-6120, Assisted
Reproduction Accessories, Regulatory Class II,
Product Code 85MOG, October 30, 2001.

control accelerates recovery and

2

Reference Number: K013703

MCO-5M

(shown stacked)

Voltage, Power

Connection

115 V

NEMA 5 -15

16 Guide to Laboratory Equipment www.sanyobiomedical.com

MCO-5M

Heated and Refrigerated Incubators

SANYO MIR series incubators are designed for general laboratory applications requiring fixed setpoint or cycling temperature control.
A selection of five cabinet sizes offers programmed operation and integrated alarms for a wide temperature range.

Heated and Refrigerated Incubators

Model Number

MIR-162

MIR-262

MIR-154

MIR-25 4

MIR-554

Volume

(cu.ft.)

3.3

93 L

5.4

153 L

4.3

123 L

8.4

238 L

14.3

406 L

Exterior Dimensions

(w x f-b x h) Heated Refrigerated

22.8 " x 23.4" x 32.3"

580 x 5 95 x 820 mm

28.7" x 25.4" x 3 4.3 "

730 x 6 45 x 870 mm

27.6" x 22.8" x 40.1"

700 x 580 x 1018 mm

27.6" x 22.8" x 63.7"

700 x 580 x 1618 mm

31.5" x 32.8 " x 71.3"

800 x 832 x 1810 mm

Programmable for multifunction laboratory applications.

Programmable

Multiple setpoints and cycling of
refrigerated incubators for a variety of
laboratory functions.

P.I.D. Controller

Microprocessor-based P.I.D.
(proportional, integral, derivative) control
with digital input, full-function alarm
and monitoring.

SANYO-Brand Refrigeration

Built by SANYO for long-lasting,
dependable operation in demanding
laboratory environments.

LCD Controller

The new LCD controller improves
user interface for better program­ming and control.

yes — 5ºC above ambient to 80 ºC

yes — 5ºC above ambient to 80 ºC

yes yes - 10ºC to 6 0ºC

yes yes - 10ºC to 6 0ºC

yes yes - 10ºC to 6 0ºC

Energy Savings: In addition to a microprocessor-controlled

high efficient heater output and compressor ON/OFF, a renewal

GREEN

product

control program and low-heat emission inner chamber fan are
newly adopted to allow high-energy saving operation over a
wider range of ambient environments.

MIR-154/MIR-254/MIR-554

Refrigerated Incubators/Environmental Testing Chambers

The SANYO MIR series offers accurate temperature control and uniformity in a •
wide range of temperatures, making them suitable for various applications.

Programmable with 12 step, 10 program capability and wide temperature range •
that goes from -10°C up to +60°C with excellent temperature uniformity.

Improved usability with modern design and reversible door, improved gentle •
air circulation that reduces media drying and adjustable low vibration.

MIR-554

MIR-254

Programmable

Temperature

Voltage, Power

Connection

115 V

NEMA 5 -15

MIR-154

MIR-162

17

Plant Growth Chamber

The model MLR series humidified plant growth chamber has a temperature range of 0°C to 50°C, with programmable lighting
for diurnal protocols in plant and insect cell culture applications.

Plant Growth Chamber

Model Number

MLR-351H

For simulation of cyclical environment conditions.

Volume

(cu.ft.)

10.4

294 L

Exterior Dimensions

29.9 " x 27.6" x 72. 2"

760 x 70 0 x 1835 mm

(w x f-b x h)

Temperature Range

(lamp off)

5ºC to 5 0º C 10ºC to º50 C 55% to 90% RH 0 to 20,000 lux

Temperature Range

(lamp on)

Microprocessor P.I.D. Control

Allows accurate, reproducible and
flexible programming of all performance
parameters with optimal energy
management; comprehensive security
monitoring and alarm functions are
standard. The temperature inside
the incubator can be set and monitored
easily by means of precise micropro­cessor temperature control with an
LCD graphic display.

Programmable

Nine user programmable steps allow
simulation of environmental conditions;
15 variable intensity fluorescent lamps
create uniform lighting.

Humidity Control

Range

Lighting

Range

Voltage, Power

Connection

115 V

NEMA 5 -20

Forced Air Circulation

Maximizes temperature uniformity
at all shelf levels.

Ergonomic Design

Slim-profile cabinet offers sophisticated
performance in minimal space.

LCD Controller

The new LCD controller improves
user interface for better programming
and control.

18 Guide to Laboratory Equipment www.sanyobiomedical.com

MLR-351H

preservation

SANYO
Preservation

World Class Design. SANYO refrigeration systems oer superior performance
and reliability, even in higher ambient temperatures and in response to frequent door
openings. The cooling system also maintains uniform temperatures throughout
the freezer, which is especially important when validation is required.

19

SANYO Preservation Systems

ICD Digital

Remote Alarm

CPU and

Touch Pad

VIP Vacuum

Insulation Panel

VIP

Battery

SAVE

VIP Plus Vacuum

Insulation Panel

VIP+

Filterless

Design

VIP Vacuum

Insulation Panel

VIP

VIP Plus Vacuum

Insulation Panel

VIP+

CPU and

Touch Pad

VIP Vacuum

Insulation Panel

VIP

Rechargeable

Battery

VIP Plus Vacuum

Insulation Panel

VIP+

Filterless

Design

Insulated

Inner Doors

ICD Digital

Display

Remote Alarm

CPU and

Touch Pad

VIP Vacuum

Insulation Panel

VIP

Service

Automatic

Alarm System

Automatic

Alarm System

Rechargeable

Battery

Rechargeable

Battery

Energy

SAVE

VIP Plus Vacuum
Insulation Panel

VIP+

Filterless

Design

VIP

VIP+

VIP Vacuum

VIP

CPU and

Touch Pad

VIP Vacuum

VIP

Remote Alarm

CPU and

Touch Pad

VIP Vacuum

VIP

VIP Vacuum

Insulation Panel

VIP

VIP+

VIP

Insulated

Inner Doors

ICD Digital

Display

Remote Alarm

CPU and

Touch Pad

VIP Vacuum

Insulation Panel

VIP

Energy

SAVE

VIP Plus Vacuum

Insulation Panel

VIP+

Filterless

Design

Insulated

Inner Doors

ICD Digital

Display

Remote Alarm

CPU and

Touch Pad

VIP Vacuum

Insulation Panel

VIP

Service

Battery

Energy

SAVE

VIP Plus Vacuum

Insulation Panel

VIP+

Filterless

Design

ICD Digital

Remote Alarm

CPU and

Touch Pad

VIP Vacuum

Insulation Panel

VIP

SAVE

VIP Plus Vacuum

Insulation Panel

VIP+

Filterless

Design

Insulated

Inner Doors

ICD Digital

Display

Remote Alarm

CPU and

Touch Pad

VIP Vacuum

VIP

ICD Digital

Display

Remote Alarm

CPU and

Touch Pad

VIP Vacuum

VIP

Insulated

Inner Doors

ICD Digital

Display

Remote Alarm

CPU and

Touch Pad

VIP Vacuum

VIP

Quiet, Reliable

Compressor

Every day, laboratories around the world depend on SANYO freezers for their ultra-low
temperature storage, reassured by an industry-leading reputation for performance and
reliability.

™

V.I.P.

Space Saving Series

-86°C Ultra-Low Freezers

MDF-U33V
MDF-U53VA
MDF-U54VC
MDF-U74VC

Twin Guard™ Series -86 DualºCool

-86°C Ultra-Low Freezers

MDF-U500VXC

Conventionally Insulated
MDF Series

-86°C Ultra-Low Freezers

MDF-U5486SC, Upright
MDF-U7486SC, Upright
MDF-594C, Chest
MDF-794C, Chest

V.I.P.™ PLUS Space Saving Series

-80°C Ultra-Low Freezers

MDF-C8V1, Chest

V.I.P.™ Space Saving Series

-150ºC Cryogenic Freezer

MDF-C2156VANC

-30°C/-35°C Biomedical Freezers

MDF-436
MDF-U333
MDF-U537
MDF-U730
MDF-U730M

Laboratory Refrigerators

MPR-721
MPR-721R
MPR-1411
MPR-1411R

Pharmaceutical Refrigerators

MPR-311D(H)
MPR-514
MPR-514R
MPR-1014
MPR-1014R

Blood Bank Refrigerators

MBR-107D(H)
MBR-304GR
MBR-704GR
MBR-1405GR

Preservation System Features

Cascade Cooling System

V.I.P.™ Vacuum Insulation Panel

™

V.I.P. PLUS
Insulation Panel

Insulated Inner Doors

CPU and Touch Pad

LCD Digital Display

Remote Alarm

Automatic Alarm System

Power Failure Alarm

Filterless Design

Air Filter

CFC-Free

Energy Savings

Vacuum

20 Guide to Laboratory Equipment www.sanyobiomedical.com

Biomedical Refrigerator
with Freezer Combination

MPR-214F
MPR-414F

General Purpose Refrigerators

SRR-23GD-MED
SRR-49GD-MED
SRR-72GD-MED

Under-Counter
Refrigerators and Freezers

SR-L6111W
SF-L6111W
SR-L4110W
SR-L4110WSEC
HF-5017W
HF-5017WSEC

Quiet, Reliable Compressors

Service

Rechargeable Battery

Patented SANYO refrigerants are non-ozone depleting,
non-flammable and environmentally safe in compliance
with the Montreal Protocol.

Insulated

Inner Doors

ICD Digital

Display

Remote Alarm

CPU and

Touch Pad

VIP Vacuum

VIP

Quiet, Reliable

Compressor

Innovation

Our reputation is built on world-class
design and refrigeration systems devel­oped specifically for ultra-low tempera­ture applications. SANYO has pioneered
the development of new technologies
for ultra-low temperature storage from
the world’s lowest temperature -150°C
mechanical freezer, the introduction of
application specific HCFC-free refriger­ants and the first -86°C freezer with
vacuum insulation (V.I.P.

In 2006, SANYO introduced the next
generation of compressors for ultra-low
freezers. Application-specific compres­sors provide new levels of durability with
significantly reduced power consump­tion, heat output and noise.

™

).

Vacuum Insulation (V.I.P.™)

SANYO was the first company to
introduce vacuum insulation panels
to ultra-low temperature freezers. The
SANYO range of V.I.P.
provide 25% more storage capacity
for a given floor area saving valuable
laboratory space.

The SANYO patented V.I.P.
insulation panel thin-wall composite is
a high-efficiency design that yields
more interior storage volume in a
conventional freezer footprint. The V.I.P.
minimizes energy transfer to and from
the ultra-low temperature interior. The
composite construction, complete with
reflective barrier film and structural
closed-cell foam, is used on all walls
and the outer door.

This advanced insulation technology
offers structural stability to eliminate
distortion, and inhibits moisture
accumulation that can lead to icing.
Aggregate insulation efficiency
minimizes compressor cycle run-time
to lower energy costs.

™

freezers typically

™

vacuum

Quality to Rely On

SANYO’s Quality Management System
is certified to ISO9001 and every SANYO
freezer undergoes at least 100 checks
throughout production to ensure the high­est quality standards are maintained.

™

SANYO freezers are available with a variety of inventory
racks to meet specific applications. Freezers can be
ordered with full-load inventory systems by selecting
one catalog number.

Barrier Film

™

Panel

V.I.P.

Interior

Rigid foamed
polyurethane

The SANYO patented V.I.P.™ vacuum insulation
panel thin-wall composite is a high-efficiency design
that yields 25% more interior storage volume in a
conventional freezer footprint.

SANYO Cool Safe™ Compressor Technology: How It Works

By apportioning the oil cooling function between specially designed SANYO Cool Safe™ compressors, and by cooling
the compressor oil to minimize compressor operating temperatures, the SANYO ultra-low temperature freezer refrig­eration system is balanced to decrease component stress, increase system longevity and reliability, and improve tem­perature uniformity necessary for better cell viability regardless of where the specimen is stored within the chamber.

Cascade Cooling System

By apportioning the oil cooling function
between specially designed SANYO
Cool Safe
the compressor oil to minimize com­pressor operating temperatures, the
SANYO ultra-low temperature freezer
refrigeration system is balanced to
decrease component stress, increase
system longevity and reliability, and
improve temperature uniformity neces­sary for better cell viability regardless
of where the specimen is stored within
the chamber.

™

compressors, and by cooling

SANYO-designed Cool Safe™ refrigeration compressors
feature innovative refrigerant feedback processes to
reduce compressor temperature, thereby extending
compressor life and minimizing heat output.

21

V.I.P.™ Series Green Product Features

SANYO V.I.P.™ Green Initiative
Program

With a capacity of up to 57,600 two-inch
vials in fiberboard boxes, the energy-sav­ing advantages of this efficient SANYO
system extend to lower per-unit storage
costs regardless of the preferred inven­tory configuration.

SANYO freezers are designed to •
support LEED certification associated
with the U.S. Green Building Council
recommendations.

Components are compliant with RoHS •
directives on the use of hazardous
materials in electrical and electronic
equipment.

The SANYO V.I.P.•
panel cabinet design offers high­density storage in a minimal footprint,
optimizing available laboratory space
and storage volume efficiencies.

Noise reduction and operating cost •
efficiencies are integrated into the
refrigeration system.

Heat output is limited to minimize the •
impact on facility HVAC demands.

A microprocessor controller oversees •
the refrigeration system to regulate
cooling cycles, reducing energy
consumption.

SANYO Cool Safe•
technology for lower compressor heat
internally and externally lower HVAC
loads.

™

vacuum insulated

™

compressor

SANYO is conscious of the need to
protect our environment and conserve
energy. As a corporate pioneer in life
science laboratory equipment and ap­pliances, and as a global source of solu­tions ranging from energy management
to solar power and alternative energies,
SANYO remains committed to providing
the best possible laboratory equipment
for research and clinical needs.

CFC Free Refrigerants

SANYO was the first ultra-low freezer
manufacturer to employ non-HCFC R508
low-stage refrigerant, now recognized
as today’s industry standard and widely
available. This non-proprietary refriger­ant is available to refrigeration service
professionals on the open market.

The high stage refrigeration system is
available to refrigeration professionals on
the open market as well.

RoHS Compliance

In 2006, RoHS (Restriction of Hazardous
Substances) legislation (EU Directive
2003/95/EU) became effective. RoHS
relates to the restriction of hazardous
substances and reductions in environ­mental pollution.

Through RoHS legislation the EU and
other participating countries are banning
toxic substances in electrical equipment
such as lead, cadmium, mercury, chro­mium 6+, PBB and PBDE.

While compliance with this legislation
has posed a significant challenge for

SANYO, all SANYO ultra-low freezers and
components are now 100% compliant to
RoHS standards.

Electrical Standards

All SANYO products including ultra-low
temperature freezers are tested and cer­tified by an NRTL (National Recognized
Testing Laboratory) to assure compliance
with US and International standards for
electrical safety prescribed in
29 CFR 1910.7( c ).

Noise Reduction

Ultra-low freezers are often located
within research and hospital laboratories
or production facilities. Users prefer
close proximity for easy access to valu­able stored products.

If operating noise from refrigeration
compressors is excessive, and/or com­pounded by installation of multiple freez­ers in adjacent locations, the working
environment is severely compromised.

SANYO has included advanced noise
abatement in all contemporary ultra-low
freezers and noise reduction levels are
well below those of competitive freez­ers. Data is
available upon request.

Inventory Management

The concept of High Density Storage
is enabled by advances in SANYO Cool
Safe™ compressor design. The cost
per 2" box of interior storage space is
significantly lower in a SANYO ultra-low

22 Guide to Laboratory Equipment www.sanyobiomedical.com

GREEN

product

Because modern laboratories are energy-intensive,
SANYO has developed a corporate-wide energy savings
and environmental impact approach to new product
development. V.I.P.™ Series freezers offer significant
benefits through a balance of refrigeration power, cabinet
construction and intelligent control over all functions.

Green Design and Performance

freezer, generating immediate return on
investment based on first costs, operat­ing costs and maintenance costs over
time.

Additionally, the placement of evaporator
surfaces within the cabinet walls achieve
exceptional documented ultra-low tem­perature uniformity, thereby permitting
investigators more freedom in placing
valuable cell lines and biologicals within
the interior cabinet, and assuring uniform
cell viability when harvesting products
from the ultra-low archive.

Because benefits of the SANYO Cool
Safe™ compressor design extend to
evaporator tubing surrounding the inte­rior chamber, and the interior chamber is
part of the thin-wall composite based on
the patented V.I.P.™ vacuum insulation
panel cabinet, SANYO can offer more
usable storage volume within the same
sq.ft. of floor space than competitive
models.

V.I.P. ™ Energy Savings

Model # MDF-U53VA MD F-U74VC

Ambient Temperature 23°C 23°C

SANYO Over Previous SANYO Model -26% -11. 2%

1.0

0.9

0.8

0.7

0.6

0.5

0.4

Dollars ($)

0.3

0.2

0.1

0.61

0

0.89

0.88

Annual CO2

Emissions by Box

Capacity

SANYO MDF-U74VC

Brand A

Brand B

Chart 1 - SANYO Freezers help the environment by reducing carbon footprint.

MD F- U74 VC

12

10

8

7.6 3

6

4

Dolla rs / Cub ic Foo t

2

0

11.11

10.93

Total Annual

Electrical Cost per

Box Capacity

SANYO MDF-U74VC

Brand A

Brand B

Chart 2 - SANYO Freezers emit less heat into the laboratory, minimizing air
conditioning costs.

Power Consumption

1.54

2.25

2.65

0.00 0.50 1.00 1.50 2.00 2.50 3.00

Watts

By Capacity

(KW/ day/ box Efficiency)

SANYO MDF-U74VC

Brand A

Brand B

Chart 3 - SANYO freezers provide reduced operational cost for highly
efficient sample storage.

23

V.I.P™ Series Space Saving -86°C Ultra-Low-Freezers

SANYO V.I.P.™ ultra-low temperature freezers offer the most advanced combination of low-temperature refrigeration, cabinet and control
technology in the clinical and life science industry. Space-saving, high-density V.I.P.™ vacuum insulation panel construction allows up to
25% more storage volume in the same or less floor space than conventional freezers.

V.I.P.™ -86ºC Ultra Low Freezers

Model Number

MDF-U33V

MDF-U53VA

MDF-U54VC

MDF- U74VC

V.I.P.™ units offer lower operational costs than conventionally insulated models. These units also offer high-density ultra-low storage solutions for the laboratory.

Volume

(cu.ft.)

11. 8

340 L

18.3

510 L

18.3

510 L

25.7

736 L

Exterior Dimensions

(w x f-b x h)

26.4" x 34.1" x 73.2"

670 x 86 7 x 1860 mm

30.3" x 34 .4" x 78 .3"

770 x 875 x 19 90 mm

30.3" x 34 .4" x 78 .3"

770 x 875 x 19 90 mm

39.8" x 34.4" x 79.1"

1010 x 875 x 2010 mm

Patented V.I.P.™
Vacuum Panel Insulation

Combination of multiple high-perfor­mance vacuum panels with high-density
foam insulation achieves thin-wall profile
for maximum interior volume in a com-

Storage

(2"/ 51 mm boxes)

216 144 21,6 00

352 224 35,200

352 224 35,200

576 384 5 7,60 0

Storage

(3"/76 mm boxes)

Storage

(2ml vials in boxes)

SANYO-Designed Compressors

SANYO’s ultra-low temperature
compressor employs a unique orienta­tion of conventional components to
reduce discharge temperatures and

compressor heat.
pact footprint. Increased cooling capacity
improves temperature recovery after
door openings.

Smart Refrigeration

Monitoring System

Status alert function uses predictive

Inner Doors Improve Uniformity

Easy-In/Easy-Out™ SANYO Eagle™
inner door latches feature ergonomic

intelligence to determine if freezer is

operating within specifications under

existing environmental conditions.
design to seal firmly against the cabinet
with one hand. High-strength, insulated
inner doors help minimize change in

MDF-U74VC

interior temperatures during
routine door openings.

MDF-U33V

Microprocessor

Comprehensive set­point, alarm, monitor­ing and diagnostic
functions supervised
by SANYO-built
microprocessor
controller with digital
display of all input/
output function.

Voltage, Power

Connection

115 V

NEMA 5 -15

115 V

NEMA 5 -20

208-230V

NEMA 6 -15

208-230V

NEMA 6 -15

24 Guide to Laboratory Equipment www.sanyobiomedical.com

Twin Guard Series™ -86 DualºCool Ultra-Low Freezer

The SANYO MDF-U500VXC Twin Guard Series™ -86 DualºCool ultra-low freezer is designed for -86°C storage of high-value biologicals. Ideal
for critical material storage in repositories, highly secure BSL4 labs, hospitals, clinics and medical research facilities. The Twin Guard Series™
introduces the concept of dual, independent, autocascade refrigeration systems contained within a single cabinet.

Twin Guard Series™ -86 DualºCool Ultra-Low Freezer

Model Number

MDF-U500VXC

The safest ultra-low freezer for long-term storage of ultra-critical biologicals.

Volume

(cu.ft.)

18.3

519 L

Twin Guard Series™ -86 DualºCool
Refrigeration System

The Twin Guard Series™ ultra-low freezer
avoids conventional cascade refrigera­tion technology by using two completely
independent one-compressor, autocas­cade cooling systems, each capable of
maintaining ultra-low temperatures.

Exterior Dimensions

(w x f-b x h)

30.3" x 34 .3" x 78.3 "

770 x 875 x 19 90 mm

Integrated LCD Control with
Graphical Display

The Twin Guard Series™ MDF-U500VXC
is managed by an integrated micropro­cessor controller with LCD information
center to simplify all freezer func­tions. Uniform ultra-low temperature
is achieved through a combination of
performance systems supervised by the
controller complete with alarm, program­ming and diagnostic protocols.

Patented V.I.P.™
Vacuum Panel Insulation

Combination of multiple high-perfor­mance vacuum panels with high-density
foam insulation achieves thin-wall profile
for maximum interior volume in a com­pact footprint. Increased cooling capacity

MDF-U5 00VXC

improves temperature recovery after
door openings.

Storage

(2"/ 51 mm boxes)

352 224 35,200

Storage

(3"/76 mm boxes)

Storage

(2ml vials in boxes)

Voltage, Power

Connection

208-230V

NEMA 6 -15

Inner Doors Improve Uniformity

Easy-In/Easy-Out™ SANYO Eagle™ inner
door latches feature ergonomic design
to seal firmly against the cabinet with
one hand. High-strength, insulated inner
doors help minimize change in interior
temperatures during routine door
openings.

Reduced Power Consumption

The SANYO Twin Guard Series™ Freezer
can be set for Normal or EcoMode
operation, depending on ambient tem­perature and load. EcoMode
mended for 90-95% of applications.
Although both refrigeration systems are
completely independent, EcoMode
establishes an overlapping cycle to
significantly reduce energy consump­tion while optimizing interior uniformity
from top-to-bottom and front-to-back for
protection of high value materials.

™

™

is recom-

™

SANYO V.I.P.™ Series freezers offer high-density
storage that effectively reduces the volumetric unit
costs of ultra-low storage.

25

MDF-U500VXC

ICD Digital

Remote Alarm

CPU and

Touch Pad

VIP Vacuum

Insulation Panel

VIP

Battery

SAVE

VIP Plus Vacuum

Insulation Panel

VIP+

Filterless

Design

VIP Vacuum

Insulation Panel

VIP

VIP Plus Vacuum

Insulation Panel

VIP+

CPU and

Touch Pad

VIP Vacuum

Insulation Panel

VIP

Rechargeable

Battery

VIP Plus Vacuum

Insulation Panel

VIP+

Filterless

Design

Insulated

Inner Doors

ICD Digital

Display

Remote Alarm

CPU and

Touch Pad

VIP Vacuum

Insulation Panel

VIP

Service

Automatic

Alarm System

Automatic

Alarm System

Rechargeable

Battery

Rechargeable

Battery

Energy

SAVE

VIP Plus Vacuum
Insulation Panel

VIP+

Filterless

Design

VIP

VIP+

VIP Vacuum

VIP

CPU and

Touch Pad

VIP Vacuum

VIP

Remote Alarm

CPU and

Touch Pad

VIP Vacuum

VIP

VIP Vacuum

Insulation Panel

VIP

VIP+

Insulated

Inner Doors

ICD Digital

Display

Remote Alarm

CPU and

Touch Pad

VIP Vacuum

Insulation Panel

VIP

Service

Battery

Energy

SAVE

VIP Plus Vacuum

Insulation Panel

VIP+

Filterless

Design

ICD Digital

Remote Alarm

CPU and

Touch Pad

VIP Vacuum

Insulation Panel

VIP

SAVE

VIP Plus Vacuum

Insulation Panel

VIP+

Filterless

Design

Insulated

Inner Doors

ICD Digital

Display

Remote Alarm

CPU and

Touch Pad

VIP Vacuum

VIP

ICD Digital

Display

Remote Alarm

CPU and

Touch Pad

VIP Vacuum

VIP

Twin Guard Series™-86°C Ultra-Low
Freezer Featuring SANYO -86 Dual°Cool
Independent Refrigeration Systems

The industry’s safest ultra-low storage solution
for high value biologicals.

The 18.3 cu.ft. / 519 L V.I.P.™ insulated
MDF-U500VXC, includes integrated
LCD performance monitor and digital
controller for comprehensive system
management, data logging, remote com­munications, alarms, predictive perfor­mance and validation. Maintenance-free,
filterless design.

The innovative design utilizing two •
independent systems allows the unit
to continue to run continuously at

-65°C in the unlikely event of one
compressor failure.

The combination of additional refrigera-•
tion intelligently managed by intuitive
microprocessor controls and integrated
into SANYO’s patented V.I.P.
panel cabinet make the most efficient
use of available floor space.

Twin Guard Series•

™

freezers signifi­cantly increase ultra-low protection
while minimizing energy costs
through a unique EcoMode
EcoMode

™

optimizes power consump­tion by orchestrating run times for
each refrigeration system in response
to cooling demands.

Ultra-Critical Installations and Applications Overview

Application Sensitivity Benefit

Stem Cells, Cord Blood, T-Cells, Engineered Tissue,
Organ/ Tissue, Vaccines, Bone Marrow, Hybridomas,
Lymphocytes, Cancer Cells, Clinical Specimens,
Fibroblasts, Ova, Sperm

BSL4 or Highly Secured Labs Restricted access to the contained laboratory

26 Guide to Laboratory Equipment www.sanyobiomedical.com

™

vacuum

™

function.

The SANYO Twin Guard Series™ -86°C ultra-low freezer with dual, independent
refrigeration systems increases reliability. The 18.3 cu.ft./519 liter upright cabinet holds
up to 352 2"/51mm boxes in standard inventory racks.

Highly sensitive to temperature fluctuations or
uneven storage temperatures at different positions
within the interior chamber.

limits serviceabilit y.

Enhanced temperature uniformit y, top-to-bottom,
front-to-back, assures stability at all inventory
locations.

Twin Guard Series
to react in the event of mechanical failure.

GREEN

product

™

extends critical time necessary

Integrated LCD control with graphical display. The Twin Guard Series™ MDF-U500VXC is managed by an integrated
microprocessor controller with LCD information center to simplify all freezer functions. Uniform ultra-low temperature
is achieved through a combination of performance systems supervised by the controller complete with alarm,
programming and diagnostic protocols.

The Safest Ultra-Low Freezer
for Long-Term Storage of Ultra­Critical Biologicals

The SANYO Twin Guard Series™ satisfies
the industry demand for safe, long­term storage for the most high-valued
materials. Two independent refrigeration
systems, combined with optional liquid
nitrogen or liquid CO
offer a circle of protection unmatched in
the marketplace. Developed for use with
conventional inventory racks and boxes,
the Twin Guard Series
age of sensitive stem cells, embryos,
cell lines, and other rare specimens.

back-up systems,

2

™

is ideal for stor-

Twin Guard Series™ -86 Dual°Cool
Refrigeration System

The Twin Guard Series™ Ultra-Low Freez­er avoids conventional cascade refrigera­tion technology by using two completely
independent one-compressor, autocas­cade cooling systems, each capable of
maintaining ultra-low temperatures.

Each refrigeration circuit includes a •
closed-loop cold-wall evaporator con­figured in parallel to the other.

Independent evaporators and cooling •
fans assure back up status at all times,
eliminating system failure due to
sub-component failure in conventional
cascade systems configured of mutu­ally dependent high- and low-stage
systems.

In the unlikely event of a compressor •
failure in one system, the remaining
system will automatically maintain a
minimum of -65°C for an indefinite
period.

In the event of a facility power failure •
with optional CO

or LN2 backup sys-

2

tem installed, the freezer will maintain

-65°C storage temperature for up to
eight hours (CO

backup system) and

2

-65°C storage temperature for up to
15 hours (LN

A unique EcoMode•

backup system).

2

™

deploys both sys-

tems in overlapping cycles to maintain

-86°C and to reduce energy consump­tion by as much as 15%.

Evaporator coils embedded in the •
patented, high-tech, SANYO V.I.P.

™

vacuum-insulated thin-wall cabinet are
strategically oriented to deliver the
best temperature uniformity at all shelf
levels, top-to-bottom and front-to-back.

New SANYO-designed Cool Safe•

™

refrigeration compressors feature inno­vative refrigerant feedback processes
to reduce compressor temperature,
thereby extending compressor life and
minimizing heat output.

Independent systems efficient ultra-low cooling
is achieved through two independent evaporator
circuits surrounding the interior chamber.

Failure Mode Comparison

Event

Fan Failure Freezer Fails

High Stage
Compressor
Failure

Low Stage
Compressor
Failure

Conventional Freezer

No Backup

Freezer Fails

Freezer Fails

Conventional Freezer

With Backup

Freezer fails,

CO

or LN2 backup

2

system offers

short-term

protection until

contents can
be removed and
repairs initiated.

SANYO

Twin Guard™ Series

If one fan fails, the second fan auto ­matically maintains energy exchange.

No high or low stage used. Two refrig­eration systems, each with a single
compressor, operate independently in
overlapping cycles during normal opera­tion. If one compressor fails internal
temperature is maintained indefinitely
at -6 5°C. Optional LN
system offers additional protection.

or CO2 backup

2

27

Conventionally Insulated MDF Series -86°C Ultra-Low Freezers (Upright)

SANYO conventionally insulated MDF series ultra-low freezers provide energy savings while minimizing carbon footprint throughout the
laboratory without compromising performance. The conventionally insulated series also maintains internal temperatures as low as

-86°C. All models use SANYO-designed compressors for ultra-low temperature applications. Manufactured with foam-in-place insulation
to maximize interior temperature uniformity, they are ideally suited for use in hospitals and laboratories for long-term preservation
and storage of blood, specimens and components, as well as material testing.

Conventionally Insulated MDF Series -86ºC Ultra-Low Freezers (Upright)

Model Number

MDF-U5486SC

MDF-U7486SC

Think Green, environmentally friendly refrigerants, RoHS compliant and low-noise operation.

Volume

(cu.ft.)

17.1

487 L

23.5

668 L

Exterior Dimensions

(w x f-b x h)

35.0 " x 34.4" x 78.3"

890 x 875 x 199 0 mm

44.5" x 34.4" x 78.3"

1130 x 875 x 1990 mm

Storage

(2"/ 51 mm boxes)

320 192 32,000

480 384 48,000

Microprocessor Controls

Comprehensive setpoint, alarm,
monitoring and diagnostic functions
based on SANYO-built microprocessor
controller with digital display of all
input/output functions.

-86ºC Ultra-Low Temperature Freezers:

Ideal -86ºC freezing environment by means of conventional insulated walls.•

Specially designed compressors for ultra-low temperature applications.•

Microprocessor temperature control with digital input for precise setting and control.•

Built-in temperature and power failure alarms (audible/visible).•

SANYO-Designed Refrigeration

Designed by SANYO specifically for
rugged ultra-low temperature applications
in a laboratory environment; CFC-free
refrigerants only. SANYO refrigeration
system delivers uniform temperatures
with increased cooling capacity. High
performance refrigeration system
with foam-in-place cabinet insulation
maximizes interior temperature unifor­mity and protects against fluctuating
ambient temperatures.

SANYO-Designed Compressors

SANYO’s ultra-low temperature com­pressor employs a unique orientation
of conventional components to reduce
discharge temperatures and compressor
heat.

Inner Doors
Improve Uniformity

Double insulation polyurethane
walls and easy open, easy close
hinged outer door latch. Two
independent and insulated inner
doors ensure maximum interior
chamber uniformity.

Storage

(3"/76 mm boxes)

MDF- U748 6SC

Storage

(2ml vials in boxes)

Voltage, Power

Connection

208/ 230V

NEMA 6 -15

208/ 230V

NEMA 6 -15

GREEN

product

Thinking Green: Environmentally friendly refrigerants,

RoHS compliant and low-noise operation.

28 Guide to Laboratory Equipment www.sanyobiomedical.com

MDF Series -80°C to -86°C Ultra-Low Freezers (Chest)

SANYO MDF series ultra-low temperature freezers maintain internal temperatures as low as -86°C (-123°F). All models use SANYO-designed
compressors for ultra-low temperature applications. Manufactured with foamed-in-place insulation, they are ideally suited for use in hospitals
and laboratories for long-term preservation and storage of blood, specimens and components, as well as materials testing.

Conventionally Insulated MDF Series -86ºC Ultra-Low Freezers (Chest)

Model Number

MDF-594C

MDF-794 C

Volume

(cu.ft.)

17. 2

487 L

24.8

702 L

Exterior Dimensions

(w x f-b x h)

79.1" x 30.3 " x 42.1"

2010 x 770 x 1070 mm

101.2" x 30.3" x 42.1"

2570 x 770 x 1070 mm

Storage

(2"/ 51 mm boxes)

351 243 35 ,100

507 351 5 0,70 0

Storage

(3"/76 mm boxes)

V.I.P.™ PLUS Space-Saving Series, -80°C MDF Ultra-Low Freezer (Chest)

Model Number

MDF-C8V1

Volume

(cu.ft.)

3.0

85 L

Think Green, V.I.P.™ offers lower operational costs than conventionally insulated models.

Microprocessor Controls

Comprehensive setpoint, alarm, monitor­ing and diagnostic functions based on
SANYO-built microprocessor controller
with digital display of all input/output
functions.

MDF-C8V1

Ultra-Low Temperature
V.I.P.™ PLUS Freezer:

Patented revolutionary vacuum •
insulation cabinet construction
reduces wall thickness and
achieves greater storage
capacity while decreasing
the footprint.

Comprehensive setpoint, •
alarm, monitoring and
diagnostic functions based on
SANYO-built microprocessor
controller with digital
LED display.

Exterior Dimensions

(w x f-b x h)

21.6" x 27.0" x 37.2"

550 x 6 85 x 945 mm

SANYO-Designed Refrigeration

Designed by SANYO specifically for rug­ged ultra-low temperature applications
in a laboratory environment; HCFC-free
refrigerants only.

Storage

(2"/ 51 mm boxes)

GREEN

product

MDF-594C

Storage

(3"/76 mm boxes)

42 30 4,200

SANYO-Designed Compressors

High-performance refrigeration system
with foam-in-place cabinet insulation
maximizes interior temperature unifor­mity and protects against fluctuating
ambient temperatures.

Thinking Green: V.I.P.™ PLUS offers lower operational

costs than conventionally insulated models.

Storage

(2ml vials in boxes)

Storage

(2ml vials in boxes)

Voltage, Power

Connection

208/ 230V

NEMA 6 -15

208/ 230V

NEMA 6 -15

Voltage, Power

Connection

115 V

NEMA 5 -15

29

-150°C Cryogenic Freezers

SANYO MDF series cryogenic freezers maintain uniform temperature of -150°C for stable, long-term preservation of cells and tissue. SANYO
V.I.P.™ PLUS Cryogenic Series -150°C ultra-low temperature freezers achieve more storage capacity than a conventionally insulated freezer
without increasing footprint.

-150ºC Cryogenic Freezers

Model Number

MDF-C2156VANC

The newly developed refrigeration system and freezer structure offers a quiet environment.

Volume

(cu.ft.)

8.2

231 L

Exterior Dimensions

(w x f-b x h)

68.1" x 30.1" x 39.8"

1730 x 765 x 1010 mm

Storage

(2"/ 51 mm boxes)

150 105 15,000

Uniform Cryogenic Temperatures

Mechanically refrigerated design pro­motes better top-to-bottom uniformity
than liquid nitrogen vapor-phase storage.

V.I.P.™ PLUS Design

Patented revolutionary vacuum insulation
cabinet construction reduces wall thick­ness and achieves more storage capacity
than a conventionally insulated freezer
without increasing the footprint.

SANYO-Designed Refrigeration

Designed by SANYO specifically
for rugged cryogenic temperature
applications in a laboratory environ­ment; CFC-free refrigerants only.

Microprocessor Temperature
Control with Digital Design

Precise setting and temperature control.
The temperature inside the freezer can
be set and monitored easily by means
of precise microprocessor temperature
control with an LCD graphic display.
Adjustable high/low temperature alarm;
power failure alarm; filter check alarm;
door ajar alarm; part replacement
time notification.

LCD Control Panel

LCD microprocessor controller features a
full-alarm package with a status alert moni­toring system. The monitoring system re­cords internal temperature up to one month
and history of door openings and closings.

Comparison of temperature distribution in a liquid nitrogen freezer (vapor phase) and SANYO’s MDF-C2156VANC
mechanically refrigerated cryogenic freezer. Graph shows temperatures at different locations within the chamber.
This data demonstrates that 100% of the MDF-C2156VANC storage space maintains uniform storage temperatures
safely below -130ºC, while temperature in LN2 vapor system is dependent on storage location.

Ideal Alternative to LN2 Storage
Mechanical Preservation

Freezer preservation provides users
with numerous advantages; uniform
cryogenic storage temperatures, no
worries about sample contamination,
no liquid supply problems, no danger
of sudden liquid eruptions and low
operational costs.

Built-In LN2 Backup System

Automatically injects LN2 to maintain
temperature during prolonged power
outage, (LN

tank not included).

2

Storage

(3"/76 mm boxes)

Storage

(2ml vials in boxes)

Voltage, Power

Connection

208/ 230V

NEMA 6 -15

Mechanical Refrigeration

Lowers LN2 consumption and mitigates
safety concerns, reduces cost of owner­ship, minimizes chance of cross-contam­ination among stored samples due to
vial breakage at extreme temperatures.

MDF-C2156VANC

30 Guide to Laboratory Equipment www.sanyobiomedical.com

-30°C/-35°C Biomedical Freezers (Chest and Upright)

SANYO MDF series biomedical freezers include chest and upright models designed for short- or intermediate-term storage at temperatures as
low as -30°C/-35°C. Constructed with high-performance laboratory and clinical-grade refrigeration systems, these freezers are used in medical,
biotechnology and industrial labs for storage of blood components, enzymes, culture media, reagents, specimens and vaccines.

-35ºC Biomedical Freezers (Chest)

Model Number

MDF-436

Volume

(cu.ft.)

15.0

426 L

-30ºC Biomedical Freezers (Upright)

Model Number

MDF-U333

MDF-U537

MDF-U730

MDF-U730M

Designed for high-performance laboratory and clinical applications.

MDF-U730M

Enzyme and Biologics Preser vation:

Storage at -30°C and -20°C easily •
with constant stable control.

Uniform temperatures throughout •
chamber using full cold wall
construction.

Because there is no defrost cycle, •
the inner chamber temperature offers
outstanding uniformity and stability.

double door, single chamber

Volume

(cu.ft.)

9.7 / 274 L

single door, single chamber

17.0 / 482 L

22.3 / 6 32 L

single door, single chamber

24.4 / 690 L

single door, single chamber

SANYO-Designed Refrigeration

Designed by SANYO with compressors
specifically for storage applications in a
laboratory environment.

Microprocessor Controls

Comprehensive setpoint, alarm, moni­toring and diagnostic functions super­vised by SANYO-built microprocessor
controller with digital display of all
input/output function.

Exterior Dimensions

(w x f-b x h) Defrost Voltage, Power Connection

49.8" x 31.8" x 35.6 "

1265 x 807 x 9 05 mm

Exterior Dimensions

(w x f-b x h) Defrost Voltage, Power Connection

24.2" x 28.9" x 63.8"

615 x 733 x 1620 mm

31.5" x 30.4" x 70.9 "

800 x 772 x 180 0 mm

30.3" x 32.7 " x 77.0"

770 x 830 x 1955 mm

30.3" x 32.7 " x 77.0"

770 x 830 x 1955 mm

Manual 115V, NEMA 5-15

Manual 115V, NEMA 5 -15

Manual 115V, NEMA 5 -15

Auto 115V, NEMA 5 -15

Manual 115V, NEMA 5 -15

High-Performance Refrigeration

Laboratory-quality refrigeration assures
stable, uniform temperatures throughout
the chamber.

Enzyme and
Biologics Preservation

(Manual Defrost Models)

Storage at -30°C and -20°C easily with
constant stable control. Uniform tem­peratures are maintained throughout the
chamber using full cold wall construction.

MDF-U333

MDF-436

MDF-537

General Purpose Storage,
Maintenance-Free

(Auto-Defrost Models)

Storage at -30°C with auto-defrost and
consistent temperature control below

-20°C during defrost cycle. Maintenance­free storage with no end user interven­tion to defrost unit and clean up conden­sate. Precision temperature uniformity
throughout chamber due to forced air
circulation with dual fans.

31

Laboratory Refrigerators

Large capacity laboratory refrigerators offer stable and reliable refrigerated environments for exacting laboratory requirements in clinical,
research, pharmaceutical and industrial applications.

Laboratory Refrigerators

Model Number

MPR-721

MPR-721R

MP R-1411

MPR-1411R

Volume

(cu.ft.)

24.2

685 L

23.7

671 L

48.2

1365 L

48.0

1360 L

Exterior Dimensions

(w x f-b x h)

30.3" x 32.7 " x 77.0"

770 x 830 x 1955 mm

30.3" x 32.7 " x 77.0"

770 x 830 x 1955 mm

56.7" x 32.7" x 76 .8"

1440 x 8 30 x 1950 mm

56.7" x 32.7" x 76 .8"

1440 x 8 30 x 1950 mm

Door

(glass)

single, swinging 4 —

single, swinging — 5

double, swinging 8 —

double, swinging — 10

Lab-ready with microprocessor control, alarm and monitoring, casters, access ports and interior lights.

Forced Air Circulation

Interior blower fans quickly restore
temperature uniformity following routine
door openings.

Adjustable Temperature Control

SANYO-built microprocessor controller,
temperature range 2°C to 23°C, with
comprehensive setpoint, alarm, monitor­ing and diagnostic functions with digital
display of all input/output functions.

Shelves

(adjustable wire)

Drawers

(solid roll-out)

Voltage, Power

Connection

115 V

NEMA 5 -15

115 V

NEMA 5 -15

115 V

NEMA 5 -15

115 V

NEMA 5 -15

SANYO Cycle Defrost

Unique cycle defrost initiates only as
required; maintains internal temperature
uniformity during process.

SANYO-Designed Compressors

Designed by SANYO specifically for
demanding laboratory applications.

Inventory Control

Choice of stainless steel roll-out drawers
or adjustable wire shelves.

MP R-14 11MPR-721R

32 Guide to Laboratory Equipment

Pharmaceutical Refrigerators

SANYO’s MPR series pharmaceutical refrigerators offer a complete and integrated solution for the growing requirements for strict and exact
storage temperatures for pharmaceuticals, medicines and temperature-sensitive biologicals. The slim design and optional sliding shelves allow
for an ergonomic easy-reach retrieval of your product..

Pharmaceutical Refrigerators

Model Number

MPR-311D(H)

MPR-514

MPR-514R

MPR-1014

MPR-1014 R

Volume

(cu.ft.)

12.0

340 L

17. 3

489 L

17.2

486 L

36.6

1037 L

36.5

1034 L

Exterior Dimensions

(w x f-b x h) Door Wire Shelves

31.4" x 17.7" x 70.8"

798 x 450 x 1796 mm

35.4" x 23.6 " x 70.5"

900 x 600 x 1790 mm

35.4" x 23.6 " x 70.5"

900 x 600 x 1790 mm

70.9" x 23.6 " x 70.5 "

1778 x 60 0 x 1790 mm

70.9" x 23.6 " x 70.5 "

1778 x 60 0 x 1790 mm

dual, sliding glass adjustable

dual, sliding glass adjustable

dual, sliding glass 1/2 adjustable, 1/2 roll -out

dual, sliding glass adjustable

dual, sliding glass 1/2 adjustable, 1/2 roll -out

Ergonomic design offers temperature stability with safe, secure and easy inventory management.

Forced Air Circulation

Positive airflow quickly restores unifor­mity following routine door openings.

Microprocessor Controls

Comprehensive setpoint, alarm, moni­toring and diagnostic functions based on
SANYO-built microprocessor controller
with digital display of all input/output
functions, adjustable temperature range
2°C to 14°C.

The Ideal +4° Pharmaceutical
Refrigeration in Capacities from

17.3 cu.ft. / 489L:

Uniform storage is unaffected by •
ambient temperature.

Remarkable cooling efficiency.•

SANYO's cyle defrost •
system.

Plenums direct •
airflow, essential
for validated
storage require­ments.

MPR-514

Voltage, Power

Connection

115 V

NEMA 5 -15

115 V

NEMA 5 -15

115 V

NEMA 5 -15

115 V

NEMA 5 -15

115 V

NEMA 5 -15

SANYO Cycle Defrost

Unique cycle defrost initiates only as
required; maintains internal tempera­ture uniformity during process.

SANYO-Designed Compressors

Designed by SANYO specifically for
rugged ultra-low temperature applica­tions in a laboratory environment;
CFC-free refrigerants only.

Inventory Control

Stainless steel interior construc­tion with roll-out or adjustable wire
shelves.

MPR-1014R

33

Blood Bank Refrigerators

SANYO blood bank refrigerators are designed to create stable, reliable temperature control pre-set to 4°C with precise top-to-bottom
temperature uniformity.

Blood Bank Refrigerators

Model Number

MBR-107D(H)

MBR-304GR

MBR-704 GR

MBR-1405GR

Volume

(cu.ft.)

2.8

79 L

10.6

300 L

21.8

617 L

45.9

1300 L

Exterior Dimensions

(w x f-b x h)

15.7" x 19.5" x 5 9.6 "

400 x 495 x 1514 mm

23.6 " x 26.8" x 72. 2"

600 x 681 x 183 4 mm

30.0 " x 32.7" x 77.0"

762 x 831 x 1955 mm

56.7" x 32.7" x 76 .8"

1440 x 8 31 x 1950 mm

Bag Capacity

(450 ml) Drawers* Shelves

Designed to meet AABB and ANRC criteria for safety and performance.

Inner Doors

Plexiglass inner doors offer additional
interior chamber temperature protection
during door openings.

Forced Air Circulation

Interior blower fans quickly restore
temperature uniformity following routine
door openings.

Temperature Recorder

Built-in recorder provides a permanent
record of cabinet pressure.

Doors*

(exterior)

32 — 4 1 2

120 5 — 1 2

360 6 — 1 3

720 12 — 2 6

*stainless steel

roll-out

*swinging glass

dual pane w/ lock

Doors

(interior)

Microprocessor
Temperature Control

SANYO-built microprocessor controller
with comprehensive alarm, monitoring
and diagnostic functions with digital
display.

SANYO-Designed Refrigeration

Designed by SANYO with compressors spe­cifically designed for blood bank storage.

SANYO Cycle Defrost

Unique cycle defrost initiates only as
required; maintains internal temperature
uniformity during process.

Voltage, Power

Connection

115 V

NEMA 5 -15

115 V

NEMA 5 -15

115 V

NEMA 5 -15

115 V

NEMA 5 -15

34 Guide to Laboratory Equipment

MBR-14 05G R

MBR-70 4GR

MBR-107D(H)

Biomedical Refrigerator with Freezer Combination

When space is at a premium, SANYO refrigerator with freezer combination offers convenience and performance in an attractive,
space-saving design.

Biomedical Refrigerator with Freezer Combination

Refrigerator

Model Number

MPR-214 F

MPR- 414F

Volume

(cu.ft.)

6.2

176 L

12.0

340 L

Designed for storage of vaccines and pharmaceuticals in the hospital, laboratory or medical office.

SANYO Cycle Defrost

Unique cycle defrost (refrigerator only)
initiates only as required; maintains inter­nal temperature uniformity during cycle
defrost. Freezer is manual defrost.

SANYO-Designed Refrigeration

SANYO-designed compressors allow
differential control of individual refrigera­tor and freezer compartments.

Validatable Storage

Laboratory-grade integrated systems
are designed to assure stored product
safety.

Freezer

Volume

(cu.ft.)

1.4

40 L

2.9

82 L

Exterior Dimensions

(w x f-b x h)

21.3" x 21.9" x 70.5"

540 x 557 x 1790 mm

31.5" x 23.6" x 71.1"

800 x 600 x 1805 mm

Temperature

Range

(forced air)

2°C to 14°C

2°C to 14°C -20°C to -30°C

Temperature

Range

(cold air)

-20°C to -30°C

Voltage, Power

MPR- 414 F

Validated Storage of Reagents, Pharmaceuticals and Biological Samples:

Ideal biologic storage environment for precise control and superior •
temperature and uniformity.

Microprocessor controller and interior forced air circulation.•

Safe and secured storage behind a keyed locking door.•

Integrated alarm functions.•

One unit with dual temperature zone needs only minimal installation space. •

Four-door design reduces air loss during door openings. •

Double-pane windows with heat reflection film reduces the condensation. •

Calibration adjustment through the control panel is available. •

The MPR series combo units have two separate specially designed •
compressors and offers quiet operation.

Connection

115 V

NEMA 5 -15

115 V

NEMA 5 -15

Microprocessor Controls

Comprehensive setpoint, alarm,
monitoring and diagnostic functions
based on SANYO-built micropro­cessor controller with digital
display of all input/output
functions.

MPR-214F

35

General Purpose Refrigerators

SANYO general purpose refrigerators are designed for general purpose storage applications in life science and industrial laboratories. Feature
reliable heavy-duty refrigeration systems for frequent door openings with optional duplex power outlet for chromatography applications.

Pharmacy Refrigerators

Model Number

SRR-23GD- MED

SRR-49GD-MED

SRR-72GD- MED

Designed for general purpose storage applications in the laboratory.

Volume

(cu.ft.)

21.0

595 L

40.0

1133 L

61.0

1700 L

Heavy-Duty Refrigeration

Designed for frequent door opening
applications.

Exterior Dimensions

(w x f-b x h) Door Wire Shelves Voltage, Power Connection

29.1" x 31.7" x 79.25"

740 x 805 x 2013 mm

49.6 " x 31.7" x 79. 25"

1260 x 80 5 x 2013 mm

74.8" x 31.7" x 79.25"

1900 x 8 05 x 2013 mm

Stainless Steel Construction

Durable exterior and interior surfaces.
Large interior for greater flexibility.

single glass, swing 4 adjustable 115V, NEMA 5-15

double glass, swing 8 adjustable 115V, NEMA 5 -15

triple glass, swing 12 adjustable 115V, NEMA 5 -15

Adjustable Temperature Control

Microprocessor temperature control
with LED readout and alarm functions.

Under-Counter Refrigerators and Freezers

Designed for the demanding standards of clinical, life science, pharmaceutical, biotechnology and industrial laboratories.

Under-Counter Refrigerators

Model Number

SR -L 6111W

SR-L4110W

SR-L4110WSEC

Volume

(cu.ft.)

6.1

173 L

4.9

139 L

4.9

139 L

Exterior Dimensions

(w x f-b x h) Temperature Display Lock Voltage, Power Connection

23.6 " x 22.5" x 34.5"

600 x 571 x 876 mm

21.4" x 22.8 " x 33.8"

544 x 579 x 859 mm

21.4" x 22.8 " x 33.8"

544 x 579 x 859 mm

1°C to 14°C Microprocessor yes yes 115V, NEMA 5 -15

4°C no no 115V, NEMA 5-15

4°C no yes 115V, NEMA 5-15

Under-Counter Freezers

Model Number

SF -L 6111W

HF-5 017 W

HF-5017WSEC

Volume

(cu.ft.)

5.4

153 L

5.0

142 L

5.0

142 L

Convenient compact refrigeration in a laboratory environment.
*Models SR-L4110WSEC and HF-5017WSEC offer additional hasp locks to accommodate a padlock.

Compact Design

Allows for easy installation under counter,
counter top, or within the knee-well of
laboratory cabinetry. Door shelves and
standard shelving maximize product
storage capacity. Some models are stack­able.

Exterior Dimensions

(w x f-b x h) Temperature Display Lock Voltage, Power Connection

23.6 " x 22.5" x 25.6 "

600 x 571 x 876 mm

21.4" x 25.4" x 33.4"

544 x 645 x 848 mm

21.4" x 25.4" x 33.4"

544 x 645 x 848 mm

-15°C to -20ºC

Microprocessor

-20°C no no 115V, NEMA 5-15

-20°C no yes 115V, NEMA 5-15

SANYO Refrigeration

Energy-efficient, whisper-quiet operation.

SF -L 6111W

yes yes 115V, NEMA 5-15

SRR-72GD -MED

General Purpose Re frigerator

SR -L 6111W

36 Guide to Laboratory Equipment

sterilization

SANYO
Sterilization

World Class Design. Accurate, high-temperature equipment for scientic research.
SANYO has always aimed to provide research support equipment that oers complete
satisfaction to its users.

37

SANYO Sterilization

Top-Loading Portable Autoclaves

Researchers waste valuable time and
energy when limited to using a centralized
building autoclave. Installation and
maintenance of central autoclaves are not
only costly but time consuming. The MLS
autoclave series is designed for individual
lab use and can be conveniently moved
from one lab to another.

Top-Loading Portable Autoclaves

MLS-3751L
MLS-3781L

Top-Loading Portable Autoclaves

Model Number

MLS- 37 51L

MLS- 37 81L

Easy mobility for sterilization on demand.

Effective Capacity

(cu.ft.)

1.8

50 L

2.6

75 L

Exterior Dimensions

478 x 632 x 748 mm

478 x 632 x 965 mm

SANYO MLS series top-loading autoclaves are a popular method of sterilization for today’s
research laboratories. Self-contained and easy to use, these reliable energy-saving autoclaves
are ideal for a wide range of applications, including liquid culture media preparation, labware
and waste sterilization. Designed to meet good laboratory practice criteria in biotechnology,
pharmaceutical and clinical laboratories. SANYO MLS series portable autoclaves deliver high
pressure steam with speed, efficiency and reliability, for research lab usage only.

(w x f-b x h)

18.8" x 24.9" x 29.4"

18.8" x 24.9" x 38.0"

Maximum

Temp.

135°C 2 8

135°C 3 12

Baskets

(included)

Flask Capacity

(1L)

Cross

Section

14.6" ( 37cm)

371 mm

14.6" ( 37cm)

371 mm

Voltage, Power

Connection

115 V

NEMA L5- 30

208/ 230V

NEMA L6- 30

Microprocessor Controls

Assures correct temperature and is
accurately maintained and easily oper­ated with one-touch operation. Steril­izing temperature is controlled by the
microprocessor within +2°C of the set
temperature in the range of 115°C to
135°C.

Process Voice Notification

The MLS series includes a voice
notification of the system process.
Each step of the process is notified
via a pre-recorded voice message,
allowing the end user to hear the
process as it is happening.

Programmable

Allows maximum flexibility in ramp up,
dwell, ramp down and cool-off protocols.

Compact Design

Maximizes use of available lab
floor space, stores easily when
not in use.

Low-Profile and Ergonomic Design

Simplifies access, easy to load and unload.

Swing-Up Lid

Opens chamber for 100% access;
eliminates side space requirement.

Printer

Optional process printer for batch
documentation.

MLS- 3751L

MLS- 3781L

38 Guide to Laboratory Equipment sanyobiomedical.com

38 Guide to Laboratory Equipment www.sanyobiomedical.com

Product Service
and Uptime Assurance

Your SANYO experience with product safety, reliability and performance is
supported by a multi-national network of factory-trained service professionals
located in all markets we serve. The serviceability of SANYO Biomedical products
is inherent to all SANYO product designs and originates in our research and
development department. Combined with customer feedback and detailed docu­mentation of field performance, SANYO product developers incorporate real-world
applications into product systems and operating parameters.

From ambient temperature and humidity fluctuations to broad electrical
voltage tolerances, SANYO Biomedical products are expected to withstand
demands in the newest of facilities as well as older labs. Central to our product
development efforts is the concept of “predictive performance”, a matrix of
electronics and control functions that sense component operation in real time,
compare performance to accepted norms and report exceptions long before
normal wear and tear causes an interruption. As a result, many SANYO Biomedical
products include self-diagnostics that permit authorized service technicians
to determine how and when service calls are required.

As SANYO continues to apply improvements in compressor and electronics
to all products, life cycle costs can be extended and downtime minimized.
SANYO service specialists are trained to perform remote and on-site diagnostics,
repair and replace worn components and offer preventative maintenance programs
suitable to your needs and budget. SANYO Biomedical also offers training to
selected facility biomedical engineers and service staff for authorized in-warranty
and post-warranty repairs.

Because SANYO Biomedical products are sold and serviced worldwide,
products acquired in one country under grant or facility-sharing programs are
easily supported if moved to facilities in the next city or around the world.

Validation Services

SANYO offers a wide range of high-quality validation services for all our equipment.
These services include on-site validation, custom validation support packages,
factory acceptance testing, and NIST traceable calibration.

Choosing SANYO as an equipment supplier and validation consultant can greatly
reduce the time and cost involved with new equipment.

Unique Services SANYO Offers:

On-site consultation•
Specialized documentation for •

each individual unit
Customized testing procedures •

based on personalized customer
requirements

No charge for documentation •
when service is purchased

Quality documents complying with •
21 CFR traceable standards

Free archiving of unexecuted •
testing protocols

Pre-Delivery and On-Site Services

Pre-delivery services include factory
acceptance testing, calibration, and
temperature mapping. On-site services
include installation qualification, operation­al qualification, performance qualification,
calibration and temperature mapping.

SANYO Connect

SANYO’s customer-driven biomedical
service program guarantees local
attention from qualified SANYO
service representatives, whenever
and wherever you need it.

New Unit Installation and Training•
Preventative Maintenance•
Warranty and Non-Warranty Repairs•
Calibration/Validation Services•
Refurbishment and Reconditioning•
Customized Service and Warranty •

Programs
Loaner Units When Needed•
In-Stock Parts for Immediate Delivery •

Prices and conditions may vary by market.

39

SALES and SERVICE NORTH AMERICA
SANYO Electric Co. Ltd. products are sold and serviced in North America by a network of factory-trained authorized independent sales and
service representatives under the direction of SANYO Biomedical Solutions Division, Wood Dale, IL (Division of SANYO North America Corporation).
Visit our website at www.sanyobiomedical.com for the latest sales and service information.

SANYO North America Corporation

Biomedical Solutions Division

1300 Michael Drive, Suite A, Wood Dale, IL 60191

Toll free USA [phone], Fax [phone]

www.sanyobiomedical.com