Benchmark Scientific Benchmark Scientific AP1096 Manual

User Manual

V1.0

Nucleic Acid

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IsoPure 96

Purification System

I

Thank you for purchasing our IsoPure 96 Nucleic Acid Purification System. This user

BENCHMARK SCIENTIFIC

PO Box 709

Edison, NJ 08818

USA

Phone: [phone]

Website: www.benchmarkscientific.com

/ www.accuris-usa.com

Email: [e-mail] /

[e-mail]

manual describes the instrument’s features, specifications, as well as complete operating
instructions, please read carefully before operation. Keep this user manual for later use.

Initial Inspection

Please check the instrument as well as all included accessories when you first open the
packaging. If you find anything damaged or missing, please contact Benchmark Scientific
or your local distributor immediately.

Version No.: 1st, November 2018

Test Equipment Depot - 800.517.8431 - 5 Commonwealth Ave, Woburn, MA 01801 TestEquipmentDepot.com

II

Safety Warnings and Guidelines

1. Important information for safe use
Users should have a clear understanding of how to use this instrument
before operation, please read this manual carefully prior to operation.

Any improper operation may cause injured or electric shock.
Please read the manual carefully and operate safely according
to the guidelines.

2. Security
The operation and maintenance and of the instrument should comply with
the basic guidelines and warnings below. Incorrect operation or
maintenance will have effect on using life, performance, and safety
features of the instrument.

The instrument is normal indoor instrument which conforms to
classⅠof GB 4793.1 standard.

Please read this manual carefully before operation. The
device must be used by experienced personnel with
appropriate training.

The operator should not repair the instrument in case any
injury or out-of warranty. If service required, please contact
Benchmark Scientific / Accuris Instruments or your local
distributor for repair.

Before powering on, please make sure the voltage of the power
supply is consistent with the required voltage. And make sure
the rated load of the power outlet is not less than required by
the instrument.

If the power cord is damaged, replace it with the same type and
specification power cord. Do not cover anything on the
instruments when using. Insert and pull the power line with hand
gently and make sure the plug completely insert to the jack.

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The temperature of the heating block is high, please do not
touch it during the operation in case any injury.

The instrument should be kept in an area with minimal dust,
away from wet areas and direct sunlight. In additional the
installation location should have sufficient ventilation, but away
from electromagnetic interference and heat sources. The vent
on this instrument are designed for ventilation. Do not cover
them in case overheat. When many instruments are used at the
same time, the distance between each instrument should be
more than 100cm.

Power off when not in use. If the instrument will not be used
for a long period of time, cover it with a cloth or plastic to
protect it from dust.

Disconnect the power cord from the jack at once in the
following cases, and contact your local distributor or Benchmark
Scientific / Accuris Instruments:

⚫ Liquid enters into the Instrument;
⚫ Instrument was rained or watered.
⚫ Abnormal operation: such as abnormal sound or smell.
⚫ Instrument dropping or outer shell damaged.
⚫ The function has obviously changed.

3. Maintenance
The instrument should be cleaned regularly using a soft cloth damp with
small amount of alcohol. If any stain on the surface of the instrument, wipe
it with soft cloth damp with cleansing cream.

4. Transportation and storage
requirements Ambient temperature: 10℃ ~
35℃ Relative humidity: ≤70%
Atmosphere pressure range: 500 ~ 1060hpa
Locate it in a well-ventilated room, away from corrosive gas.

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Contents

Chapter 1 Introduction.................................................................................................................. 1

1. Application .......................................................................................................................................... 1

2. Contraindication .............................................................................................................................. 1

3. Service Life .......................................................................................................................................... 1

Chapter 2 Specifications ............................................................................................................... 2

1. Working Conditions ....................................................................................................................... 2

2. Basic Parameters ............................................................................................................................. 2

3. Overall Dimensions ....................................................................................................................... 3

Chapter 3 Basic Operating Instructions .............................................................................. 4

1. Structures............................................................................................................................................. 4

2. Touch Screen ..................................................................................................................................... 6

Chapter 4 Operations ..................................................................................................................... 7

1. Power Connection .......................................................................................................................... 7

2. Kits Installation ................................................................................................................................ 7

3. Detailed Operations ...................................................................................................................... 8

3.1. Start-up Interface ....................................................................................................................... 8

3.2. Run Program Interface ............................................................................................................ 8

3.3. Manage Program ................................................................................................ ...................... 15

3.4. System Settings..........................................................................................................................19

3.5. UV Sterilization ................................................................................................ .......................... 23

3.6. Help ...................................................................................................................................................24

Chapter 5 Trouble Shooting .....................................................................................................25

1. Troubleshooting ............................................................................................................................25

2. Software Error Alarm List ........................................................................................................26

Chapter 6 Accessory ......................................................................................................................27

Chapter 7 Abbreviations and Tags .......................................................................................28

1. Abbreviations ..................................................................................................................................28

2. Tags ........................................................................................................................................................29

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IsoPure 96 Operation Manual Chapter 1 Introduction

Chapter 1 Introduction

The IsoPure 96 nucleic acid purification instrument is a newly launched
automatic extraction and purification system for DNA/RNA, proteins and
cells. It can absorb, transfer and release magnetic beads by magnetic rod
and magnetic rod sleeve to separate magnetic beads and samples. The
operation is automatic, fast and simple. Users can extract 1~24, 1~48 or
1~96 samples simultaneously with special kits. Auto pure series can extract
samples of animal/plant tissue, blood and body fluids, etc with different
kinds of magnetic bead nucleic acid extraction reagents. It is mainly used
for the extraction and purification of nucleic acid from human body
samples.

1. Application
This instrument is suitable for the extraction and purification of nucleic

acids in animal and plant tissues, blood and body fluids and other
samples(mainly used in human body samples).

2. Contraindication
No contraindication.

3. Service Life

Service life of the instrument is five years.
For production date, please see the label on back of the instrument.

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IsoPure 96 Operation Manual Chapter 2 Specifications

Chapter 2 Specifications

1. Working Conditions

Environmental Temperature: 10 C～35 C
Relative Humidity: ≤70%
Input Voltage: AC 100～240V，50Hz/60Hz

2. Basic Parameters

Model

IsoPure Mini

IsoPure 96

Parameters

Principle

Magnetic Particle Method, Magnet type

Sample Volume

200μL-10000μL

50μL—1000μL

Throughput

24

96

Stability

CV≤5%

Extraction time

10 ~ 60min/time

Temperature

Room temperature to 120℃ for lysis and elution

control module

Temp. Accuracy

±1

℃

Vibrateand mix

10 different speeds for option

Operation

7 inch color touch screen, mouse can be connected

Programs

8 groups of programs can be preset, and can store 100

groups of programs

Program

Including create, edit, delete and protocol mode

management

Extension

With USB port and Ethernet port

interface

Network

Extended Ethernet remote control, WiFi function.

Power Supply

AC100-240V, 50Hz/60Hz, 250VA

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IsoPure 96 Operation Manual Chapter 2 Specifications

3. Overall Dimensions

Unit: mm

Fig 1

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IsoPure 96 Operation Manual Chapter 3 Basic Operating Instructions

Chapter 3 Basic Operating Instructions

This chapter mainly introduces structures, basic operation keys,

displays, as well as preparations before starting up. Please read this
chapter carefully before using this instrument.

1. Structures

1.1. Front

Display

Shortcut keys
and indicator

Cabin door

Fig 2

1.2. Back

Power Switch

USB Port

Screw to remove

Fan

transparent cover

Screw to remove
panel

Power
Socket Fuse

Fig 3

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IsoPure 96 Operation Manual Chapter 3 Basic Operating Instructions

1.3. Cabin Door
The cabin door of IsoPure 96 can be opened which is convenient for

cleaning and maintenance.

Cabin door

Magnetic rod
Magnetic rod’s tip

Heating plate

Fig 4

1.4. Transparent Cover
The transparent cover is on the right side of the instrument which is

for placing or taking out kits.

The cover can be removed which makes it convenient matching with

automatic liquid transfer wrokstation.

Screw for quick removel

Transparent cover

Fig 5

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IsoPure 96 Operation Manual Chapter 3 Basic Operating Instructions

2. Touch Screen

Indicator light

TAB

RUN

Display screen

STOP

Fig 6

Display screen: Touch screen, mouse also can be connected for operation.
TAB: Select shortcut program.
RUN: Start the shortcut program and run the instrument.
STOP: Stop the operation.

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