SAFETY DATA SHEET
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 1: Identification of the substance/mixture and of the company/
undertaking
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Product name
:
1.1 Product identifier
1.3 Details of the supplier of the safety data sheet
e-mail address of person
responsible for this SDS
:
pdl-msds_author@agilent.com
1.2 Relevant identified uses of the substance or mixture and uses advised against
Part no.
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
5190-0485-1
EN12916:2006 IP391-07
Sys. Cal. Std. 2
5190-0485-2
1.4 Emergency telephone number
Emergency telephone
number (with hours of
operation)
:
CHEMTREC®: +(44)-870-8200418
Agilent Technologies Manufacturing GmbH & Co. KG
Hewlett-Packard-Str. 8
76337 Waldbronn
Germany
0800 603 1000
Part no. (chemical kit)
:
5190-0485
Reagents and Standards for Analytical Chemistry Laboratory Use
EN12916:2006 IP391-07 Sys. Cal. Std. 1
1 x 1 ml
EN12916:2006 IP391-07 Sys. Cal. Std. 2
1 x 1 ml
Material uses
:
SECTION 2: Hazards identification
Classification according to Regulation (EC) No. 1272/2008 [CLP/GHS]
2.1 Classification of the substance or mixture
Product definition
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Mixture
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Mixture
EN12916:2006
IP391-07 Sys. Cal.
Std. 1
H225
FLAMMABLE LIQUIDS
Category 2
H315
SKIN CORROSION/IRRITATION
Category 2
H336
SPECIFIC TARGET ORGAN TOXICITY - SINGLE EXPOSURE
(Narcotic effects)
Category 3
H304
ASPIRATION HAZARD
Category 1
H400
SHORT-TERM (ACUTE) AQUATIC HAZARD
Category 1
H410
LONG-TERM (CHRONIC) AQUATIC HAZARD
Category 1
EN12916:2006
IP391-07 Sys. Cal.
Std. 2
H225
FLAMMABLE LIQUIDS
Category 2
H315
SKIN CORROSION/IRRITATION
Category 2
H336
SPECIFIC TARGET ORGAN TOXICITY - SINGLE EXPOSURE
Category 3
Date of issue/Date of revision
:
1/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 2: Hazards identification
See Section 11 for more detailed information on health effects and symptoms.
See Section 16 for the full text of the H statements declared above.
2.2 Label elements
Hazard pictograms
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Signal word
:
Hazard statements
:
Prevention
:
Precautionary statements
Response
:
Storage
:
Disposal
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Danger
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Danger
EN12916:2006 IP391-07
Sys. Cal. Std. 1
H225 - Highly flammable liquid and vapour.
H304 - May be fatal if swallowed and enters airways.
H315 - Causes skin irritation.
H336 - May cause drowsiness or dizziness.
H410 - Very toxic to aquatic life with long lasting effects.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
H225 - Highly flammable liquid and vapour.
H304 - May be fatal if swallowed and enters airways.
H315 - Causes skin irritation.
H336 - May cause drowsiness or dizziness.
H410 - Very toxic to aquatic life with long lasting effects.
EN12916:2006 IP391-07
Sys. Cal. Std. 1
P210 - Keep away from heat, hot surfaces, sparks, open
flames and other ignition sources. No smoking.
P273 - Avoid release to the environment.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
P210 - Keep away from heat, hot surfaces, sparks, open
flames and other ignition sources. No smoking.
P273 - Avoid release to the environment.
EN12916:2006 IP391-07
Sys. Cal. Std. 1
P391 - Collect spillage.
P301 + P310 - IF SWALLOWED: Immediately call a
POISON CENTER or doctor.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
P391 - Collect spillage.
P301 + P310 - IF SWALLOWED: Immediately call a
POISON CENTER or doctor.
EN12916:2006 IP391-07
Sys. Cal. Std. 1
P403 + P233 - Store in a well-ventilated place. Keep
container tightly closed.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
P403 + P233 - Store in a well-ventilated place. Keep
container tightly closed.
EN12916:2006 IP391-07
Sys. Cal. Std. 1
P501 - Dispose of contents and container in accordance
with all local, regional, national and international regulations.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
P501 - Dispose of contents and container in accordance
with all local, regional, national and international regulations.
(Narcotic effects)
H304
ASPIRATION HAZARD
Category 1
H400
SHORT-TERM (ACUTE) AQUATIC HAZARD
Category 1
H410
LONG-TERM (CHRONIC) AQUATIC HAZARD
Category 1
Date of issue/Date of revision
:
2/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 2: Hazards identification
:
Other hazards which do
not result in
classification
EN12916:2006 IP391-07
Sys. Cal. Std. 1
None known.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
None known.
Supplemental label
elements
Tactile warning of
danger
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Not applicable.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Not applicable.
:
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Not applicable.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Not applicable.
Special packaging requirements
Hazardous ingredients
:
2.3 Other hazards
Annex XVII - Restrictions
on the manufacture,
placing on the market
and use of certain
dangerous substances,
mixtures and articles
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Not applicable.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Not applicable.
EN12916:2006 IP391-07
Sys. Cal. Std. 1
- heptane
EN12916:2006 IP391-07
Sys. Cal. Std. 2
- heptane
Product meets the
criteria for PBT or vPvB
according to
Regulation (EC) No.
1907/2006, Annex XIII
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
This mixture does not contain any substances that are
assessed to be a PBT or a vPvB.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
This mixture does not contain any substances that are
assessed to be a PBT or a vPvB.
SECTION 3: Composition/information on ingredients
EN12916:2006 IP391-07 Sys. Cal.
Std. 1
Mixture
EN12916:2006 IP391-07 Sys. Cal.
Std. 2
Mixture
:
3.1 Substances
Product/ingredient name
EN12916:2006 IP391-07 Sys. Cal.
Std. 1
n-Heptane
EC: 205-563-8
CAS: 142-82-5
Index: 601-008-00-2
≥90
Flam. Liq. 2, H225
Skin Irrit. 2, H315
STOT SE 3, H336
Asp. Tox. 1, H304
Aquatic Acute 1, H400 (M=1)
Aquatic Chronic 1, H410 (M=1)
[1] [2]
Cyclohexane
EC: 203-806-2
CAS: 110-82-7
Index: 601-017-00-1
≤3
Flam. Liq. 2, H225
Skin Irrit. 2, H315
STOT SE 3, H336
Asp. Tox. 1, H304
Aquatic Acute 1, H400 (M=1)
Aquatic Chronic 1, H410 (M=1)
[1] [2]
naphthalene
EC: 202-049-5
CAS: 91-20-3
Index: 601-052-00-2
≤0.3
Acute Tox. 4, H302
Carc. 2, H351
Aquatic Acute 1, H400 (M=1)
Aquatic Chronic 1, H410 (M=1)
[1] [2]
EN12916:2006 IP391-07 Sys. Cal.
Identifiers
%
Type
Regulation (EC) No. 1272/2008
[CLP]
Date of issue/Date of revision
:
3/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 3: Composition/information on ingredients
There are no additional ingredients present which, within the current knowledge of the supplier and in the concentrations
applicable, are classified as hazardous to health or the environment and hence require reporting in this section.
[1] Substance classified with a health or environmental hazard
[2] Substance with a workplace exposure limit
[3] Substance meets the criteria for PBT according to Regulation (EC) No. 1907/2006, Annex XIII
[4] Substance meets the criteria for vPvB according to Regulation (EC) No. 1907/2006, Annex XIII
[5] Substance of equivalent concern
[6] Additional disclosure due to company policy
Type
Std. 2
n-Heptane
EC: 205-563-8
CAS: 142-82-5
Index: 601-008-00-2
≥90
Flam. Liq. 2, H225
Skin Irrit. 2, H315
STOT SE 3, H336
Asp. Tox. 1, H304
Aquatic Acute 1, H400 (M=1)
Aquatic Chronic 1, H410 (M=1)
[1] [2]
See Section 16 for the full text
of the H statements declared
above.
SECTION 4: First aid measures
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Immediately flush eyes with plenty of water, occasionally
lifting the upper and lower eyelids. Check for and remove
any contact lenses. Continue to rinse for at least 10 minutes.
Get medical attention.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Immediately flush eyes with plenty of water, occasionally
lifting the upper and lower eyelids. Check for and remove
any contact lenses. Continue to rinse for at least 10 minutes.
Get medical attention.
4.1 Description of first aid measures
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Remove victim to fresh air and keep at rest in a position
comfortable for breathing. If it is suspected that fumes are
still present, the rescuer should wear an appropriate mask
or self-contained breathing apparatus. If not breathing, if
breathing is irregular or if respiratory arrest occurs, provide
artificial respiration or oxygen by trained personnel. It may
be dangerous to the person providing aid to give mouth-tomouth resuscitation. Get medical attention. If necessary,
call a poison center or physician. If unconscious, place in
recovery position and get medical attention immediately.
Maintain an open airway. Loosen tight clothing such as a
collar, tie, belt or waistband.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Remove victim to fresh air and keep at rest in a position
comfortable for breathing. If it is suspected that fumes are
still present, the rescuer should wear an appropriate mask
or self-contained breathing apparatus. If not breathing, if
breathing is irregular or if respiratory arrest occurs, provide
artificial respiration or oxygen by trained personnel. It may
be dangerous to the person providing aid to give mouth-tomouth resuscitation. Get medical attention. If necessary,
call a poison center or physician. If unconscious, place in
recovery position and get medical attention immediately.
Maintain an open airway. Loosen tight clothing such as a
collar, tie, belt or waistband.
Inhalation
Eye contact
:
:
Date of issue/Date of revision
:
4/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 4: First aid measures
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Get medical attention immediately. Call a poison center or
physician. Wash out mouth with water. Remove dentures if
any. Remove victim to fresh air and keep at rest in a
position comfortable for breathing. If material has been
swallowed and the exposed person is conscious, give small
quantities of water to drink. Stop if the exposed person feels
sick as vomiting may be dangerous. Aspiration hazard if
swallowed. Can enter lungs and cause damage. Do not
induce vomiting. If vomiting occurs, the head should be kept
low so that vomit does not enter the lungs. Never give
anything by mouth to an unconscious person. If
unconscious, place in recovery position and get medical
attention immediately. Maintain an open airway. Loosen
tight clothing such as a collar, tie, belt or waistband.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Get medical attention immediately. Call a poison center or
physician. Wash out mouth with water. Remove dentures if
any. Remove victim to fresh air and keep at rest in a
position comfortable for breathing. If material has been
swallowed and the exposed person is conscious, give small
quantities of water to drink. Stop if the exposed person feels
sick as vomiting may be dangerous. Aspiration hazard if
swallowed. Can enter lungs and cause damage. Do not
induce vomiting. If vomiting occurs, the head should be kept
low so that vomit does not enter the lungs. Never give
anything by mouth to an unconscious person. If
unconscious, place in recovery position and get medical
attention immediately. Maintain an open airway. Loosen
tight clothing such as a collar, tie, belt or waistband.
Skin contact
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Flush contaminated skin with plenty of water. Remove
contaminated clothing and shoes. Continue to rinse for at
least 10 minutes. Get medical attention. Wash clothing
before reuse. Clean shoes thoroughly before reuse.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Flush contaminated skin with plenty of water. Remove
contaminated clothing and shoes. Continue to rinse for at
least 10 minutes. Get medical attention. Wash clothing
before reuse. Clean shoes thoroughly before reuse.
Ingestion
:
:
Protection of first-aiders
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
No action shall be taken involving any personal risk or
without suitable training. If it is suspected that fumes are
still present, the rescuer should wear an appropriate mask
or self-contained breathing apparatus. It may be dangerous
to the person providing aid to give mouth-to-mouth
resuscitation.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
No action shall be taken involving any personal risk or
without suitable training. If it is suspected that fumes are
still present, the rescuer should wear an appropriate mask
or self-contained breathing apparatus. It may be dangerous
to the person providing aid to give mouth-to-mouth
resuscitation.
4.2 Most important symptoms and effects, both acute and delayed
Potential acute health effects
Inhalation
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Can cause central nervous system (CNS) depression. May
cause drowsiness or dizziness.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Can cause central nervous system (CNS) depression. May
cause drowsiness or dizziness.
EN12916:2006 IP391-07
Sys. Cal. Std. 1
No known significant effects or critical hazards.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
No known significant effects or critical hazards.
:
Eye contact
Date of issue/Date of revision
:
5/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 4: First aid measures
Notes to physician
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Treat symptomatically. Contact poison treatment specialist
immediately if large quantities have been ingested or inhaled.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Treat symptomatically. Contact poison treatment specialist
immediately if large quantities have been ingested or inhaled.
:
Specific treatments
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Can cause central nervous system (CNS) depression. May
be fatal if swallowed and enters airways.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Can cause central nervous system (CNS) depression. May
be fatal if swallowed and enters airways.
:
Ingestion
Skin contact
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Causes skin irritation.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Causes skin irritation.
Over-exposure signs/symptoms
Skin contact
Ingestion
Inhalation
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Adverse symptoms may include the following:
nausea or vomiting
headache
drowsiness/fatigue
dizziness/vertigo
unconsciousness
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Adverse symptoms may include the following:
nausea or vomiting
headache
drowsiness/fatigue
dizziness/vertigo
unconsciousness
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Adverse symptoms may include the following:
nausea or vomiting
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Adverse symptoms may include the following:
nausea or vomiting
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Adverse symptoms may include the following:
irritation
redness
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Adverse symptoms may include the following:
irritation
redness
:
:
:
Eye contact
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Adverse symptoms may include the following:
pain or irritation
watering
redness
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Adverse symptoms may include the following:
pain or irritation
watering
redness
4.3 Indication of any immediate medical attention and special treatment needed
EN12916:2006 IP391-07
Sys. Cal. Std. 1
No specific treatment.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
No specific treatment.
:
Date of issue/Date of revision
:
6/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 5: Firefighting measures
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Promptly isolate the scene by removing all persons from the
vicinity of the incident if there is a fire. No action shall be
taken involving any personal risk or without suitable training.
Move containers from fire area if this can be done without
risk. Use water spray to keep fire-exposed containers cool.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Promptly isolate the scene by removing all persons from the
vicinity of the incident if there is a fire. No action shall be
taken involving any personal risk or without suitable training.
Move containers from fire area if this can be done without
risk. Use water spray to keep fire-exposed containers cool.
Hazardous combustion
products
Hazards from the
substance or mixture
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Decomposition products may include the following materials:
carbon dioxide
carbon monoxide
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Decomposition products may include the following materials:
carbon dioxide
carbon monoxide
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Highly flammable liquid and vapour. Runoff to sewer may
create fire or explosion hazard. In a fire or if heated, a
pressure increase will occur and the container may burst,
with the risk of a subsequent explosion. The vapour/gas is
heavier than air and will spread along the ground. Vapours
may accumulate in low or confined areas or travel a
considerable distance to a source of ignition and flash back.
This material is very toxic to aquatic life with long lasting
effects. Fire water contaminated with this material must be
contained and prevented from being discharged to any
waterway, sewer or drain.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Highly flammable liquid and vapour. Runoff to sewer may
create fire or explosion hazard. In a fire or if heated, a
pressure increase will occur and the container may burst,
with the risk of a subsequent explosion. The vapour/gas is
heavier than air and will spread along the ground. Vapours
may accumulate in low or confined areas or travel a
considerable distance to a source of ignition and flash back.
This material is very toxic to aquatic life with long lasting
effects. Fire water contaminated with this material must be
contained and prevented from being discharged to any
waterway, sewer or drain.
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Use dry chemical,
CO₂,
water spray (fog) or foam.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Use dry chemical,
CO₂,
water spray (fog) or foam.
5.1 Extinguishing media
:
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Do not use water jet.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Do not use water jet.
Suitable extinguishing
media
:
Unsuitable extinguishing
media
:
5.2 Special hazards arising from the substance or mixture
5.3 Advice for firefighters
Special precautions for
fire-fighters
:
Date of issue/Date of revision
:
7/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 5: Firefighting measures
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Fire-fighters should wear appropriate protective equipment
and self-contained breathing apparatus (SCBA) with a full
face-piece operated in positive pressure mode. Clothing for
fire-fighters (including helmets, protective boots and gloves)
conforming to European standard EN 469 will provide a
basic level of protection for chemical incidents.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Fire-fighters should wear appropriate protective equipment
and self-contained breathing apparatus (SCBA) with a full
face-piece operated in positive pressure mode. Clothing for
fire-fighters (including helmets, protective boots and gloves)
conforming to European standard EN 469 will provide a
basic level of protection for chemical incidents.
Special protective
equipment for firefighters
:
SECTION 6: Accidental release measures
6.2 Environmental
precautions
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Avoid dispersal of spilt material and runoff and contact with
soil, waterways, drains and sewers. Inform the relevant
authorities if the product has caused environmental pollution
(sewers, waterways, soil or air). Water polluting material.
May be harmful to the environment if released in large
quantities. Collect spillage.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Avoid dispersal of spilt material and runoff and contact with
soil, waterways, drains and sewers. Inform the relevant
authorities if the product has caused environmental pollution
(sewers, waterways, soil or air). Water polluting material.
May be harmful to the environment if released in large
quantities. Collect spillage.
6.3 Methods and material for containment and cleaning up
6.1 Personal precautions, protective equipment and emergency procedures
For non-emergency
personnel
:
For emergency
responders
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
No action shall be taken involving any personal risk or
without suitable training. Evacuate surrounding areas.
Keep unnecessary and unprotected personnel from entering.
Do not touch or walk through spilt material. Shut off all
ignition sources. No flares, smoking or flames in hazard
area. Avoid breathing vapour or mist. Provide adequate
ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective
equipment.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
No action shall be taken involving any personal risk or
without suitable training. Evacuate surrounding areas.
Keep unnecessary and unprotected personnel from entering.
Do not touch or walk through spilt material. Shut off all
ignition sources. No flares, smoking or flames in hazard
area. Avoid breathing vapour or mist. Provide adequate
ventilation. Wear appropriate respirator when ventilation is
inadequate. Put on appropriate personal protective
equipment.
EN12916:2006 IP391-07
Sys. Cal. Std. 1
If specialised clothing is required to deal with the spillage,
take note of any information in Section 8 on suitable and
unsuitable materials. See also the information in "For nonemergency personnel".
EN12916:2006 IP391-07
Sys. Cal. Std. 2
If specialised clothing is required to deal with the spillage,
take note of any information in Section 8 on suitable and
unsuitable materials. See also the information in "For nonemergency personnel".
:
Date of issue/Date of revision
:
8/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 6: Accidental release measures
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Stop leak if without risk. Move containers from spill area.
Use spark-proof tools and explosion-proof equipment.
Dilute with water and mop up if water-soluble. Alternatively,
or if water-insoluble, absorb with an inert dry material and
place in an appropriate waste disposal container. Dispose
of via a licensed waste disposal contractor.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Stop leak if without risk. Move containers from spill area.
Use spark-proof tools and explosion-proof equipment.
Dilute with water and mop up if water-soluble. Alternatively,
or if water-insoluble, absorb with an inert dry material and
place in an appropriate waste disposal container. Dispose
of via a licensed waste disposal contractor.
Methods for cleaning up
:
6.4 Reference to other
sections
See Section 1 for emergency contact information.
See Section 8 for information on appropriate personal protective equipment.
See Section 13 for additional waste treatment information.
:
SECTION 7: Handling and storage
7.1 Precautions for safe handling
Protective measures
:
Advice on general
occupational hygiene
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Put on appropriate personal protective equipment (see
Section 8). Do not swallow. Avoid contact with eyes, skin
and clothing. Avoid breathing vapour or mist. Avoid release
to the environment. Use only with adequate ventilation.
Wear appropriate respirator when ventilation is inadequate.
Do not enter storage areas and confined spaces unless
adequately ventilated. Keep in the original container or an
approved alternative made from a compatible material, kept
tightly closed when not in use. Store and use away from
heat, sparks, open flame or any other ignition source. Use
explosion-proof electrical (ventilating, lighting and material
handling) equipment. Use only non-sparking tools. Take
precautionary measures against electrostatic discharges.
Empty containers retain product residue and can be
hazardous. Do not reuse container.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Put on appropriate personal protective equipment (see
Section 8). Do not swallow. Avoid contact with eyes, skin
and clothing. Avoid breathing vapour or mist. Avoid release
to the environment. Use only with adequate ventilation.
Wear appropriate respirator when ventilation is inadequate.
Do not enter storage areas and confined spaces unless
adequately ventilated. Keep in the original container or an
approved alternative made from a compatible material, kept
tightly closed when not in use. Store and use away from
heat, sparks, open flame or any other ignition source. Use
explosion-proof electrical (ventilating, lighting and material
handling) equipment. Use only non-sparking tools. Take
precautionary measures against electrostatic discharges.
Empty containers retain product residue and can be
hazardous. Do not reuse container.
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Eating, drinking and smoking should be prohibited in areas
where this material is handled, stored and processed.
Workers should wash hands and face before eating,
drinking and smoking. Remove contaminated clothing and
protective equipment before entering eating areas. See also
Section 8 for additional information on hygiene measures.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Eating, drinking and smoking should be prohibited in areas
where this material is handled, stored and processed.
Workers should wash hands and face before eating,
drinking and smoking. Remove contaminated clothing and
protective equipment before entering eating areas. See also
Section 8 for additional information on hygiene measures.
Date of issue/Date of revision
:
9/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 7: Handling and storage
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Store between the following temperatures: 18 to 25°C (64.4
to 77°F). Store in accordance with local regulations. Store
in a segregated and approved area. Store in original
container protected from direct sunlight in a dry, cool and
well-ventilated area, away from incompatible materials (see
Section 10) and food and drink. Store locked up. Eliminate
all ignition sources. Separate from oxidising materials.
Keep container tightly closed and sealed until ready for use.
Containers that have been opened must be carefully
resealed and kept upright to prevent leakage. Do not store
in unlabelled containers. Use appropriate containment to
avoid environmental contamination. See Section 10 for
incompatible materials before handling or use.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Store between the following temperatures: 18 to 25°C (64.4
to 77°F). Store in accordance with local regulations. Store
in a segregated and approved area. Store in original
container protected from direct sunlight in a dry, cool and
well-ventilated area, away from incompatible materials (see
Section 10) and food and drink. Store locked up. Eliminate
all ignition sources. Separate from oxidising materials.
Keep container tightly closed and sealed until ready for use.
Containers that have been opened must be carefully
resealed and kept upright to prevent leakage. Do not store
in unlabelled containers. Use appropriate containment to
avoid environmental contamination. See Section 10 for
incompatible materials before handling or use.
7.2 Conditions for safe storage, including any incompatibilities
7.3 Specific end use(s)
Recommendations
:
:
Industrial sector specific
solutions
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Not available.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Not available.
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Industrial applications, Professional applications.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Industrial applications, Professional applications.
Seveso Directive - Reporting thresholds
Danger criteria
Category
EN12916:2006 IP391-07 Sys. Cal. Std. 1
P5c
5000 tonne
50000 tonne
E1
100 tonne
200 tonne
EN12916:2006 IP391-07 Sys. Cal. Std. 2
P5c
5000 tonne
50000 tonne
E1
100 tonne
200 tonne
Notification and MAPP
threshold
Safety report threshold
Storage
:
Date of issue/Date of revision
:
10/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 8: Exposure controls/personal protection
Recommended
monitoring procedures
If this product contains ingredients with exposure limits, personal, workplace
atmosphere or biological monitoring may be required to determine the effectiveness of
the ventilation or other control measures and/or the necessity to use respiratory
protective equipment. Reference should be made to monitoring standards, such as the
following: European Standard EN 689 (Workplace atmospheres - Guidance for the
assessment of exposure by inhalation to chemical agents for comparison with limit
values and measurement strategy) European Standard EN 14042 (Workplace
atmospheres - Guide for the application and use of procedures for the assessment of
exposure to chemical and biological agents) European Standard EN 482 (Workplace
atmospheres - General requirements for the performance of procedures for the
measurement of chemical agents) Reference to national guidance documents for
methods for the determination of hazardous substances will also be required.
:
EN12916:2006 IP391-07 Sys. Cal.
Std. 1
n-Heptane
DNEL
Long term Oral
149 mg/kg
bw/day
General
population
Systemic
DNEL
Long term Dermal
149 mg/kg
bw/day
General
population
Systemic
DNEL
Long term Dermal
300 mg/kg
bw/day
Workers
Systemic
DNEL
Long term
Inhalation
447 mg/m³
General
population
Systemic
DNEL
Long term
Inhalation
2085 mg/
m³
Workers
Systemic
Cyclohexane
DNEL
Long term Oral
59.4 mg/kg
bw/day
General
population
Systemic
DNEL
Long term
Inhalation
206 mg/m³
General
population
Local
DNEL
Long term
Inhalation
206 mg/m³
General
population
Systemic
DNEL
Short term
Inhalation
412 mg/m³
General
population
Local
DNEL
Short term
Inhalation
412 mg/m³
General
population
Systemic
DNEL
Short term
700 mg/m³
Workers
Local
Product/ingredient name
Exposure
Value
Population
Effects
8.1 Control parameters
DNELs/DMELs
Type
Occupational exposure limits
Product/ingredient name
Exposure limit values
EN12916:2006 IP391-07 Sys. Cal. Std. 1
n-Heptane
EH40/2005 WELs (United Kingdom (UK), 1/2020).
TWA: 500 ppm 8 hours.
TWA: 2085 mg/m³ 8 hours.
Cyclohexane
EH40/2005 WELs (United Kingdom (UK), 1/2020).
STEL: 1050 mg/m³ 15 minutes.
STEL: 300 ppm 15 minutes.
TWA: 100 ppm 8 hours.
TWA: 350 mg/m³ 8 hours.
naphthalene
EU OEL (Europe, 10/2019). Notes: list of indicative
occupational exposure limit values
TWA: 10 ppm 8 hours.
TWA: 50 mg/m³ 8 hours.
EN12916:2006 IP391-07 Sys. Cal. Std. 2
n-Heptane
EH40/2005 WELs (United Kingdom (UK), 1/2020).
TWA: 500 ppm 8 hours.
TWA: 2085 mg/m³ 8 hours.
Date of issue/Date of revision
:
11/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 8: Exposure controls/personal protection
Hand protection
Chemical-resistant, impervious gloves complying with an approved standard should be
worn at all times when handling chemical products if a risk assessment indicates this is
necessary. Considering the parameters specified by the glove manufacturer, check
during use that the gloves are still retaining their protective properties. It should be
noted that the time to breakthrough for any glove material may be different for different
glove manufacturers. In the case of mixtures, consisting of several substances, the
protection time of the gloves cannot be accurately estimated.
Safety eyewear complying with an approved standard should be used when a risk
assessment indicates this is necessary to avoid exposure to liquid splashes, mists,
gases or dusts. If contact is possible, the following protection should be worn, unless
the assessment indicates a higher degree of protection: chemical splash goggles.
Eye/face protection
:
:
Skin protection
Appropriate engineering
controls
:
Use only with adequate ventilation. Use process enclosures, local exhaust ventilation or
other engineering controls to keep worker exposure to airborne contaminants below any
recommended or statutory limits. The engineering controls also need to keep gas,
vapour or dust concentrations below any lower explosive limits. Use explosion-proof
ventilation equipment.
Wash hands, forearms and face thoroughly after handling chemical products, before
eating, smoking and using the lavatory and at the end of the working period.
Appropriate techniques should be used to remove potentially contaminated clothing.
Wash contaminated clothing before reusing. Ensure that eyewash stations and safety
showers are close to the workstation location.
8.2 Exposure controls
Hygiene measures
:
Inhalation
DNEL
Long term
Inhalation
700 mg/m³
Workers
Local
DNEL
Short term
Inhalation
700 mg/m³
Workers
Systemic
DNEL
Long term
Inhalation
700 mg/m³
Workers
Systemic
DNEL
Long term Dermal
1186 mg/
kg bw/day
General
population
Systemic
DNEL
Long term Dermal
2016 mg/
kg bw/day
Workers
Systemic
naphthalene
DNEL
Long term Dermal
3.57 mg/kg
bw/day
Workers
Systemic
DNEL
Long term
Inhalation
25 mg/m³
Workers
Local
DNEL
Long term
Inhalation
25 mg/m³
Workers
Systemic
EN12916:2006 IP391-07 Sys. Cal.
Std. 2
n-Heptane
DNEL
Long term Oral
149 mg/kg
bw/day
General
population
Systemic
DNEL
Long term Dermal
149 mg/kg
bw/day
General
population
Systemic
DNEL
Long term Dermal
300 mg/kg
bw/day
Workers
Systemic
DNEL
Long term
Inhalation
447 mg/m³
General
population
Systemic
DNEL
Long term
Inhalation
2085 mg/
m³
Workers
Systemic
PNECs
No PNECs available
Individual protection measures
Date of issue/Date of revision
:
12/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 8: Exposure controls/personal protection
Based on the hazard and potential for exposure, select a respirator that meets the
appropriate standard or certification. Respirators must be used according to a
respiratory protection program to ensure proper fitting, training, and other important
aspects of use.
Respiratory protection
:
Personal protective equipment for the body should be selected based on the task being
performed and the risks involved and should be approved by a specialist before
handling this product. When there is a risk of ignition from static electricity, wear antistatic protective clothing. For the greatest protection from static discharges, clothing
should include anti-static overalls, boots and gloves. Refer to European Standard EN
1149 for further information on material and design requirements and test methods.
:
Environmental exposure
controls
:
Emissions from ventilation or work process equipment should be checked to ensure
they comply with the requirements of environmental protection legislation. In some
cases, fume scrubbers, filters or engineering modifications to the process equipment
will be necessary to reduce emissions to acceptable levels.
Body protection
:
Other skin protection
Appropriate footwear and any additional skin protection measures should be selected
based on the task being performed and the risks involved and should be approved by a
specialist before handling this product.
SECTION 9: Physical and chemical properties
Physical state
Melting point/freezing point
EN12916:2006
IP391-07 Sys. Cal. Std.
1
Liquid.
EN12916:2006
IP391-07 Sys. Cal. Std.
2
Liquid.
EN12916:2006
IP391-07 Sys. Cal. Std.
1
-91°C
EN12916:2006
IP391-07 Sys. Cal. Std.
2
-91°C
EN12916:2006
IP391-07 Sys. Cal. Std.
1
Not available.
EN12916:2006
IP391-07 Sys. Cal. Std.
2
Not available.
Odour
pH
EN12916:2006
IP391-07 Sys. Cal. Std.
1
Colourless.
EN12916:2006
IP391-07 Sys. Cal. Std.
2
Colourless.
Colour
EN12916:2006
IP391-07 Sys. Cal. Std.
1
Not available.
EN12916:2006
IP391-07 Sys. Cal. Std.
2
Not available.
EN12916:2006
IP391-07 Sys. Cal. Std.
1
Not available.
EN12916:2006
IP391-07 Sys. Cal. Std.
2
Not available.
Odour threshold
:
:
:
:
:
:
9.1 Information on basic physical and chemical properties
Appearance
Date of issue/Date of revision
:
13/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 9: Physical and chemical properties
EN12916:2006
IP391-07 Sys. Cal. Std.
1
98°C
EN12916:2006
IP391-07 Sys. Cal. Std.
2
98°C
Initial boiling point and
boiling range
Vapour pressure
Relative density
Vapour density
Solubility(ies)
EN12916:2006
IP391-07 Sys. Cal. Std.
1
0.684
EN12916:2006
IP391-07 Sys. Cal. Std.
2
0.684
EN12916:2006
IP391-07 Sys. Cal. Std.
1
3.5 [Air = 1]
EN12916:2006
IP391-07 Sys. Cal. Std.
2
3.5 [Air = 1]
EN12916:2006
IP391-07 Sys. Cal. Std.
1
Not available.
EN12916:2006
IP391-07 Sys. Cal. Std.
2
Not available.
EN12916:2006
IP391-07 Sys. Cal. Std.
1
Insoluble in the following materials: cold water and hot
water.
EN12916:2006
IP391-07 Sys. Cal. Std.
2
Insoluble in the following materials: cold water and hot
water.
Evaporation rate
EN12916:2006
IP391-07 Sys. Cal. Std.
1
Not available.
EN12916:2006
IP391-07 Sys. Cal. Std.
2
Not available.
Flash point
EN12916:2006
IP391-07 Sys. Cal. Std.
1
Closed cup: -1.11°C
EN12916:2006
IP391-07 Sys. Cal. Std.
2
Closed cup: -1.11°C
EN12916:2006
IP391-07 Sys. Cal. Std.
1
Lower: 1.05%
Upper: 6.7%
EN12916:2006
IP391-07 Sys. Cal. Std.
2
Lower: 1.05%
Upper: 6.7%
Upper/lower flammability or
explosive limits
:::
:
:
:
:
:
Flammability (solid, gas)
:
EN12916:2006
IP391-07 Sys. Cal. Std.
1
Not applicable.
EN12916:2006
IP391-07 Sys. Cal. Std.
2
Not applicable.
Date of issue/Date of revision
:
14/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 9: Physical and chemical properties
Auto-ignition temperature
EN12916:2006
IP391-07 Sys. Cal. Std.
1
215°C
EN12916:2006
IP391-07 Sys. Cal. Std.
2
215°C
EN12916:2006
IP391-07 Sys. Cal. Std.
1
Not available.
EN12916:2006
IP391-07 Sys. Cal. Std.
2
Not available.
EN12916:2006
IP391-07 Sys. Cal. Std.
1
Not available.
EN12916:2006
IP391-07 Sys. Cal. Std.
2
Not available.
Viscosity
EN12916:2006
IP391-07 Sys. Cal. Std.
1
Not available.
EN12916:2006
IP391-07 Sys. Cal. Std.
2
Not available.
Partition coefficient: noctanol/water
Explosive properties
:
:
:
:
EN12916:2006
IP391-07 Sys. Cal. Std.
1
Not available.
EN12916:2006
IP391-07 Sys. Cal. Std.
2
Not available.
Oxidising properties
:
9.2 Other information
Decomposition temperature
:
EN12916:2006
IP391-07 Sys. Cal. Std.
1
Not available.
EN12916:2006
IP391-07 Sys. Cal. Std.
2
Not available.
No additional information.
SECTION 10: Stability and reactivity
EN12916:2006 IP391-07
Sys. Cal. Std. 1
The product is stable.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
The product is stable.
10.2 Chemical stability
:
10.3 Possibility of
hazardous reactions
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Under normal conditions of storage and use, hazardous
reactions will not occur.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Under normal conditions of storage and use, hazardous
reactions will not occur.
10.1 Reactivity
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
No specific test data related to reactivity available for this
product or its ingredients.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
No specific test data related to reactivity available for this
product or its ingredients.
Date of issue/Date of revision
:
15/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 10: Stability and reactivity
10.6 Hazardous
decomposition products
10.4 Conditions to avoid
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Avoid all possible sources of ignition (spark or flame). Do not
pressurise, cut, weld, braze, solder, drill, grind or expose
containers to heat or sources of ignition. Do not allow vapour
to accumulate in low or confined areas.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Avoid all possible sources of ignition (spark or flame). Do not
pressurise, cut, weld, braze, solder, drill, grind or expose
containers to heat or sources of ignition. Do not allow vapour
to accumulate in low or confined areas.
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Under normal conditions of storage and use, hazardous
decomposition products should not be produced.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Under normal conditions of storage and use, hazardous
decomposition products should not be produced.
:
:
10.5 Incompatible
materials
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Reactive or incompatible with the following materials:
oxidising materials
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Reactive or incompatible with the following materials:
oxidising materials
SECTION 11: Toxicological information
Acute toxicity
EN12916:2006 IP391-07
Sys. Cal. Std. 1
n-Heptane
LC50 Inhalation Vapour
Rat
103 g/m³
4 hours
LC50 Inhalation Vapour
Rat
48000 ppm
4 hours
Cyclohexane
LC50 Inhalation Vapour
Rat - Male,
Female
>32880 mg/m³
4 hours
LD50 Oral
Rat
6240 mg/kg
-
naphthalene
LD50 Dermal
Rabbit
>20 g/kg
-
LD50 Oral
Rat
490 mg/kg
-
EN12916:2006 IP391-07
Sys. Cal. Std. 2
n-Heptane
LC50 Inhalation Vapour
Rat
103 g/m³
4 hours
LC50 Inhalation Vapour
Rat
48000 ppm
4 hours
Product/ingredient name
Result
Species
Dose
Exposure
Irritation/Corrosion
11.1 Information on toxicological effects
Acute toxicity estimates
Product/ingredient name
EN12916:2006 IP391-07 Sys. Cal. Std. 1
n-Heptane
N/A
N/A
N/A
103
N/A
Cyclohexane
6240
N/A
N/A
N/A
N/A
naphthalene
490
N/A
N/A
N/A
N/A
EN12916:2006 IP391-07 Sys. Cal. Std. 2
n-Heptane
N/A
N/A
N/A
103
N/A
Oral (mg/
kg)
Dermal
(mg/kg)
Inhalation
(gases)
(ppm)
Inhalation
(vapours)
(mg/l)
Inhalation
(dusts
and mists)
(mg/l)
Date of issue/Date of revision
:
16/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 11: Toxicological information
Carcinogenicity
Mutagenicity
Conclusion/Summary
:
Not available.
EN12916:2006 IP391-07
Sys. Cal. Std. 1
naphthalene
Skin - Severe irritant
Rabbit
-
24 hours
0.05 Ml
-
Product/ingredient name
Result
Score
Exposure
Observation
Sensitiser
Conclusion/Summary
:
Not available.
Species
Potential acute health effects
Conclusion/Summary
:
Not available.
Teratogenicity
Conclusion/Summary
:
Not available.
Reproductive toxicity
Conclusion/Summary
:
Not available.
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Routes of entry anticipated: Oral, Dermal, Inhalation.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Routes of entry anticipated: Oral, Dermal, Inhalation.
Specific target organ toxicity (single exposure)
Specific target organ toxicity (repeated exposure)
Product/ingredient name
Category
Aspiration hazard
Product/ingredient name
Result
Route of
exposure
Target organs
Information on likely
routes of exposure
:
EN12916:2006 IP391-07 Sys. Cal. Std. 1
EN12916:2006 IP391-07 Sys. Cal. Std. 1
ASPIRATION HAZARD - Category 1
n-Heptane
ASPIRATION HAZARD - Category 1
Cyclohexane
ASPIRATION HAZARD - Category 1
EN12916:2006 IP391-07 Sys. Cal. Std. 2
EN12916:2006 IP391-07 Sys. Cal. Std. 2
ASPIRATION HAZARD - Category 1
n-Heptane
ASPIRATION HAZARD - Category 1
EN12916:2006 IP391-07 Sys. Cal. Std. 1
n-Heptane
Category 3
-
Narcotic effects
Cyclohexane
Category 3
-
Narcotic effects
EN12916:2006 IP391-07 Sys. Cal. Std. 2
n-Heptane
Category 3
-
Narcotic effects
Not available.
Inhalation
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Can cause central nervous system (CNS) depression. May
cause drowsiness or dizziness.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Can cause central nervous system (CNS) depression. May
cause drowsiness or dizziness.
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Can cause central nervous system (CNS) depression. May
be fatal if swallowed and enters airways.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Can cause central nervous system (CNS) depression. May
be fatal if swallowed and enters airways.
:
Ingestion
Skin contact
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Causes skin irritation.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Causes skin irritation.
Date of issue/Date of revision
:
17/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 11: Toxicological information
Potential chronic health effects
EN12916:2006 IP391-07
Sys. Cal. Std. 1
No known significant effects or critical hazards.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
No known significant effects or critical hazards.
:
Eye contact
Symptoms related to the physical, chemical and toxicological characteristics
Skin contact
Ingestion
Inhalation
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Adverse symptoms may include the following:
nausea or vomiting
headache
drowsiness/fatigue
dizziness/vertigo
unconsciousness
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Adverse symptoms may include the following:
nausea or vomiting
headache
drowsiness/fatigue
dizziness/vertigo
unconsciousness
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Adverse symptoms may include the following:
nausea or vomiting
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Adverse symptoms may include the following:
nausea or vomiting
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Adverse symptoms may include the following:
irritation
redness
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Adverse symptoms may include the following:
irritation
redness
:
:
:
Eye contact
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Adverse symptoms may include the following:
pain or irritation
watering
redness
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Adverse symptoms may include the following:
pain or irritation
watering
redness
Delayed and immediate effects as well as chronic effects from short and long-term exposure
Short term exposure
Long term exposure
Potential immediate
effects
Potential delayed
effects
:
:
Potential immediate
effects
Potential delayed
effects
::Not available.
Not available.
Not available.
Not available.
Date of issue/Date of revision
:
18/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 11: Toxicological information
EN12916:2006 IP391-07
Sys. Cal. Std. 1
No known significant effects or critical hazards.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
No known significant effects or critical hazards.
General
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
No known significant effects or critical hazards.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
No known significant effects or critical hazards.
Carcinogenicity
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
No known significant effects or critical hazards.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
No known significant effects or critical hazards.
Mutagenicity
:
Other information
:
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Adverse symptoms may include the following: Repeated
exposure may cause skin dryness or cracking.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Adverse symptoms may include the following: Repeated
exposure may cause skin dryness or cracking.
EN12916:2006 IP391-07
Sys. Cal. Std. 1
No known significant effects or critical hazards.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
No known significant effects or critical hazards.
Reproductive toxicity
:
SECTION 12: Ecological information
12.1 Toxicity
EN12916:2006 IP391-07
Sys. Cal. Std. 1
n-Heptane
Acute LC50 375000 μg/l Fresh water
Fish - Oreochromis
mossambicus
96 hours
Chronic NOEC 0.17 mg/l Fresh water
Daphnia - Daphnia magna
21 days
Cyclohexane
Acute LC50 4530 μg/l Fresh water
Fish - Pimephales promelas
96 hours
naphthalene
Acute EC50 1.6 mg/l Fresh water
Daphnia - Daphnia magna Neonate
48 hours
Acute LC50 2350 μg/l Marine water
Crustaceans - Palaemonetes
pugio
48 hours
Acute LC50 213 μg/l Fresh water
Fish - Melanotaenia fluviatilis Larvae
96 hours
Chronic NOEC 0.5 mg/l Marine water
Crustaceans - Uca pugnax Adult
3 weeks
Chronic NOEC 1.5 mg/l Fresh water
Fish - Oreochromis
mossambicus
60 days
EN12916:2006 IP391-07
Sys. Cal. Std. 2
n-Heptane
Acute LC50 375000 μg/l Fresh water
Fish - Oreochromis
mossambicus
96 hours
Chronic NOEC 0.17 mg/l Fresh water
Daphnia - Daphnia magna
21 days
Product/ingredient name
Species
Result
Exposure
12.2 Persistence and degradability
Not available.
Date of issue/Date of revision
:
19/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 12: Ecological information
Mobility
Not available.
:
LogP
ow
BCF
Potential
12.3 Bioaccumulative potential
12.6 Other adverse effects
No known significant effects or critical hazards.
Product/ingredient name
EN12916:2006 IP391-07
Sys. Cal. Std. 1
n-Heptane
4.66
552
high
Cyclohexane
3.44
167
low
naphthalene
3.4
36.5 to 168
low
EN12916:2006 IP391-07
Sys. Cal. Std. 2
n-Heptane
4.66
552
high
Product/ingredient name
Aquatic half-life
Photolysis
Biodegradability
EN12916:2006 IP391-07
Sys. Cal. Std. 1
n-Heptane
--Readily
Cyclohexane
--Readily
naphthalene
--Readily
EN12916:2006 IP391-07
Sys. Cal. Std. 2
n-Heptane
--Readily
12.4 Mobility in soil
Soil/water partition
coefficient (KOC)
Not available.
:
12.5 Results of PBT and vPvB assessment
:
This mixture does not contain any substances that are assessed to be a PBT or a vPvB.
SECTION 13: Disposal considerations
The classification of the product may meet the criteria for a hazardous waste.
Hazardous waste
:
The generation of waste should be avoided or minimised wherever possible. Disposal
of this product, solutions and any by-products should at all times comply with the
requirements of environmental protection and waste disposal legislation and any
regional local authority requirements. Dispose of surplus and non-recyclable products
via a licensed waste disposal contractor. Waste should not be disposed of untreated to
the sewer unless fully compliant with the requirements of all authorities with jurisdiction.
:
Methods of disposal
13.1 Waste treatment methods
Product
Packaging
Methods of disposal
:
Special precautions
:
The generation of waste should be avoided or minimised wherever possible. Waste
packaging should be recycled. Incineration or landfill should only be considered when
recycling is not feasible.
This material and its container must be disposed of in a safe way. Care should be
taken when handling emptied containers that have not been cleaned or rinsed out.
Empty containers or liners may retain some product residues. Vapour from product
residues may create a highly flammable or explosive atmosphere inside the container.
Do not cut, weld or grind used containers unless they have been cleaned thoroughly
internally. Avoid dispersal of spilt material and runoff and contact with soil, waterways,
drains and sewers.
Date of issue/Date of revision
:
20/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 14: Transport information
Remarks
: De minimis quantities
14.6 Special precautions
for user
:
Transport within user’s premises:
always transport in closed containers that are
upright and secure. Ensure that persons transporting the product know what to do in the
event of an accident or spillage.
The environmentally hazardous substance mark is not required when transported in
sizes of ≤5 L or ≤5 kg.
Hazard identification number
33
Limited quantity
1 L
Tunnel code
(D/E)
The marine pollutant mark is not required when transported in sizes of ≤5 L or ≤5 kg.
Emergency schedules
F-E, _S-D_
Additional information
The environmentally hazardous substance mark may appear if required by other
transportation regulations.
Quantity limitation
Passenger and Cargo Aircraft: 5 L. Packaging instructions: 353.
Cargo Aircraft Only: 60 L. Packaging instructions: 364. Limited Quantities - Passenger
Aircraft: 1 L. Packaging instructions: Y341.
ADR/RID
IMDG
IATA
:::
HEPTANES
3
II
HEPTANES
3
II
UN1206
UN1206
ADR/RID
IMDG
IATA
14.1 UN number
14.2 UN proper
shipping name
14.3 Transport
hazard class(es)
14.4 Packing
group
14.5
Environmental
hazards
Yes.
Yes.
Yes. The environmentally
hazardous substance mark is
not required.
UN1206
Heptanes
3
II
14.7 Transport in bulk
according to IMO
instruments
:
Not available.
SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
EU Regulation (EC) No. 1907/2006 (REACH)
Annex XIV - List of substances subject to authorisation
Substances of very high concern
None of the components are listed.
Annex XIV
None of the components are listed.
Annex XVII - Restrictions on the manufacture, placing on the market and use of certain dangerous
substances, mixtures and articles
Date of issue/Date of revision
:
21/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 15: Regulatory information
Other EU regulations
EN12916:2006 IP391-07
Sys. Cal. Std. 1
Not applicable.
EN12916:2006 IP391-07
Sys. Cal. Std. 2
Not applicable.
Label
:
Seveso Directive
This product is controlled under the Seveso Directive.
Danger criteria
Category
EN12916:2006 IP391-07 Sys. Cal. Std. 1
P5c
E1
EN12916:2006 IP391-07 Sys. Cal. Std. 2
P5c
E1
Ozone depleting substances (1005/2009/EU)
Not listed.
Prior Informed Consent (PIC) (649/2012/EU)
Not listed.
International regulations
Chemical Weapon Convention List Schedules I, II & III Chemicals
Montreal Protocol
Not listed.
Stockholm Convention on Persistent Organic Pollutants
Not listed.
Rotterdam Convention on Prior Informed Consent (PIC)
Not listed.
UNECE Aarhus Protocol on POPs and Heavy Metals
EN12916:2006 IP391-07 Sys. Cal. Std. 1
PAHs
POPs - Annex 3
Listed
Ingredient name
List name
Status
Europe
:
All components are listed or exempted.
Inventory list
Australia
:
Not determined.
Canada
:
All components are listed or exempted.
China
:
Not determined.
Not listed.
EN12916:2006 IP391-07 Sys. Cal. Std. 1
EN12916:2006 IP391-07 Sys. Cal. Std. 1
3
heptane
205-563-8
142-82-5
3
cyclohexane
203-806-2
110-82-7
3, 57
o-xylene
202-422-2
95-47-6
3
EN12916:2006 IP391-07 Sys. Cal. Std. 2
EN12916:2006 IP391-07 Sys. Cal. Std. 2
3
heptane
205-563-8
142-82-5
3
chrysene
205-923-4
218-01-9
28, 50, 72
Ingredient name
Restriction
EC number
CAS number
Date of issue/Date of revision
:
22/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 15: Regulatory information
15.2 Chemical safety
assessment
This product contains substances for which Chemical Safety Assessments might
still be required.
:
Japan
:
Japan inventory (ENCS)
: Not determined.
Japan inventory (ISHL)
: Not determined.
Republic of Korea
:
Not determined.
New Zealand
:
All components are listed or exempted.
Philippines
:
Not determined.
Taiwan
:
All components are listed or exempted.
United States
:
All components are active or exempted.
Turkey
:
Not determined.
Thailand
:
Not determined.
Viet Nam
:
All components are listed or exempted.
SECTION 16: Other information
Indicates information that has changed from previously issued version.
Abbreviations and
acronyms
:
Full text of abbreviated H statements
Procedure used to derive the classification according to Regulation (EC) No. 1272/2008 [CLP/GHS]
Classification
Justification
EN12916:2006 IP391-07 Sys. Cal. Std. 1
Flam. Liq. 2, H225
On basis of test data
Skin Irrit. 2, H315
Calculation method
STOT SE 3, H336
Calculation method
Asp. Tox. 1, H304
Expert judgment
Aquatic Acute 1, H400
Calculation method
Aquatic Chronic 1, H410
Calculation method
EN12916:2006 IP391-07 Sys. Cal. Std. 2
Flam. Liq. 2, H225
On basis of test data
Skin Irrit. 2, H315
Calculation method
STOT SE 3, H336
Calculation method
Asp. Tox. 1, H304
Expert judgment
Aquatic Acute 1, H400
Calculation method
Aquatic Chronic 1, H410
Calculation method
EN12916:2006 IP391-07 Sys. Cal. Std. 1
H225
Highly flammable liquid and vapour.
H302
Harmful if swallowed.
H304
May be fatal if swallowed and enters airways.
H315
Causes skin irritation.
H336
May cause drowsiness or dizziness.
H351
Suspected of causing cancer.
H400
Very toxic to aquatic life.
H410
Very toxic to aquatic life with long lasting effects.
EN12916:2006 IP391-07 Sys. Cal. Std. 2
ATE = Acute Toxicity Estimate
CLP = Classification, Labelling and Packaging Regulation [Regulation (EC) No.
1272/2008]
DMEL = Derived Minimal Effect Level
DNEL = Derived No Effect Level
EUH statement = CLP-specific Hazard statement
N/A = Not available
PBT = Persistent, Bioaccumulative and Toxic
PNEC = Predicted No Effect Concentration
RRN = REACH Registration Number
vPvB = Very Persistent and Very Bioaccumulative
Date of issue/Date of revision
:
23/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
EN12916:2006 IP391-07 Sys. Cal. Std. 1,2, Part Number 5190-0485
Conforms to Regulation (EC) No. 1907/2006 (REACH), Annex II, as amended by Commission Regulation (EU)
2015/830 - United Kingdom (UK)
SECTION 16: Other information
Date of issue/ Date of
revision
Version
Notice to reader
Date of previous issue
:::
28/01/2021
21/05/2018
3
Disclaimer: The information contained in this document is based on Agilent’s state of knowledge at the time of
preparation. No warranty as to its accurateness, completeness or suitability for a particular purpose is
expressed or implied.
Full text of classifications [CLP/GHS]
H225
Highly flammable liquid and vapour.
H304
May be fatal if swallowed and enters airways.
H315
Causes skin irritation.
H336
May cause drowsiness or dizziness.
H400
Very toxic to aquatic life.
H410
Very toxic to aquatic life with long lasting effects.
EN12916:2006 IP391-07 Sys. Cal. Std. 1
Acute Tox. 4
ACUTE TOXICITY - Category 4
Aquatic Acute 1
SHORT-TERM (ACUTE) AQUATIC HAZARD - Category 1
Aquatic Chronic 1
LONG-TERM (CHRONIC) AQUATIC HAZARD - Category 1
Asp. Tox. 1
ASPIRATION HAZARD - Category 1
Carc. 2
CARCINOGENICITY - Category 2
Flam. Liq. 2
FLAMMABLE LIQUIDS - Category 2
Skin Irrit. 2
SKIN CORROSION/IRRITATION - Category 2
STOT SE 3
SPECIFIC TARGET ORGAN TOXICITY - SINGLE EXPOSURE Category 3
EN12916:2006 IP391-07 Sys. Cal. Std. 2
Aquatic Acute 1
SHORT-TERM (ACUTE) AQUATIC HAZARD - Category 1
Aquatic Chronic 1
LONG-TERM (CHRONIC) AQUATIC HAZARD - Category 1
Asp. Tox. 1
ASPIRATION HAZARD - Category 1
Flam. Liq. 2
FLAMMABLE LIQUIDS - Category 2
Skin Irrit. 2
SKIN CORROSION/IRRITATION - Category 2
STOT SE 3
SPECIFIC TARGET ORGAN TOXICITY - SINGLE EXPOSURE Category 3
Date of issue/Date of revision
:
24/24
28/01/2021
Date of previous issue
:
21/05/2018
Version
:
3
Loading...