Agilent Dako User Manual

Autostainer Link Solution for IHC
The complete IHC solution you can trust
Manage All Your Slides With One Solution
Stay ahead of the changing needs In IHC
At Agilent, our aim is to provide the tools you need to deliver the right diagnosis to the right patient on time, every time.
We understand that your particular needs are unique, as no two labs are the same – yet quality is important for every lab.
And the ever-increasing need to process more slides in less time and with less resources puts pressure on your lab’s productivity.
The Autostainer Link solution delivers:
High-quality results, slide after slide, to
ensure correct diagnoses
Maximum versatility with reagents and run
options to meet changing needs
High productivity to ensure that results are
delivered on time
Autostainer Link - the fourth generation
Autostainer solution based on 50 years of experience developing leading-edge technology for the pathology lab. Includes FLEX Ready-to-Use reagents, DakoLink software, PT Link and Autostainer Link 48.
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Stay ahead of the changing needs in IHC
Manage all your slides with one solution
High quality
Instrument precision and stability
PT Link and Autostainer Link 48 contribute to reliable, high­quality results slide after slide
Optimized reagents and protocols
Plug-and-play reagents and protocols enable correct diagnosis on tissue ranging from low expression to high expression of the marker
Robust tracking and reporting
The Autostainer Link solution
DakoLink software helps you achieve lab accreditation and link the right results to the right patient
Maximum versatility
Broad and expanding reagent portfolio
Large menu of antibodies and several companion diagnostic kits available for Autostainer Link 48 to meet the needs of clinical and research labs
Flexible run options
Automated double staining and split runs enable you to manage complex patient cases and to maintain optimal productivity and quality
Open system
Flexible protocols allow you to introduce new reagents and validate them for use in your lab’s diagnostic routine
Autostainer Link 48
A compact, bench-top, open system for staining IHC slides, controlled by protocols in the DakoLink software
DakoLink software
DakoLink with LIS and LAN connectivity for full lab integration includes the optimized and validated protocols that control the total solution
Dako Coverslipper
IHC slides go straight to automatic mounting and coverslipping after staining and dehydration
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High productivity
Fast processing with low turnaround time
Shorten the time to diagnosis by processing a full batch of 48 slides in less than 3 hours1 – or accommodate a patient-case workflow by staining as many as 24 slides in less than 2 hours
Less need to change reagents
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FLEX Ready-to-Use reagents
FLEX RTU antibodies and EnVision FLEX/FLEX+ visualization systems are integrated and optimized in the Autostainer Link solution
PT Link
Integrated pre-treatment module combines deparaffinization, rehydration and target retrieval in one step
Minimize hands-on time and process entire patient cases more efficiently with 42 onboard reagent positions
Parallel processing and overnight runs
Achieve high productivity by performing pre-treatment and staining in parallel; and increase throughput with overnight runs in both PT Link and Autostainer Link 48
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Straight to coverslipping
Move slides straight to coverslipping after staining and dehydration – no need to carry out further manual wash steps
Separation of hazardous waste
Create a safer lab environment and reduce your cost of waste handling with the automatic separation of hazardous waste
... and results
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The Confidence that Comes With High Quality
FLEX RTU antibodies designed for Autostainer solutions
– Plug and play RTU reagents optimized for optimal performance
on Dako instrumentation
– Protocol alignment to ensure optimal throughput
– Robust protocols compensate for pre-analytical variations
FLEX RTU - trusted and proven
– Broad portfolio of high quality IVD antibodies
– Proven visualization with low complexity and high sensitivity
– Optimized validated protocols developed in collaboration with leading experts
Maximum versatility – the one solution to meet all your needs
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pharmDx – An expanding portfolio of advanced companion diagnostic kits
including HercepTest and PD-L1*
IHC – High-quality antibodies for diagnostic use either as FLEX Ready-to-Use
or concentrates
Visualization options – Choose your preferred system: EnVision FLEX or
EnVision FLEX+
Unlimited possibilities – Open protocols and split runs allow you to
customize assays and optimize your diagnostic routine
Melanoma stained with Melan A , code IR633 Breast ductal carcinoma in situ stained
with Myosin Heavy Chain, code IR066
* Please visit www.agilent.com to check for PD-L1
availabiltiy in your area.
Burkitt lymphoma/leukemia stained with Ki-67, code IR626
Colon adenocarcinoma stained with Postmeiotic Segregation Increased 2 (PMS2), code IR087
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Non-small cell lung carcinoma stained with PD-L1 IHC 22C3 pharmDx, code SK006
Non-squamous non-small cell lung carcinoma stained with PD-L1 IHC 28-8 pharmDx, code SK005
Keep your lab a step ahead
At Agilent, we provide integrated solutions that are designed to meet your needs and help your lab deliver the correct results to the right patient every time. The entire range of complementary products we offer exemplifies our focus on certainty, scientific advancement and lasting partnerships with our customers.
Ready-to-Use reagents
Dako Omnis
Dako CoverStainer
Autostainer Link
DakoLink
The Dako Autostainer Link solution delivers high-quality staining, maximum versatility and high productivity.
Artisan Link Pro
For additional information on Autostainer Link or other Dako solutions, contact your local Agilent representative or visit www.agilent.com
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References
1. Colley EC, Stead RH: Optimized Immunohistochemistry Workflow Facilitated by New Autostainer Link 48 Software. Bowmanville, ON, Canada (2011).
2. Hansen SK: Dako IHC Solution at Laboratorium Pathologie. Enschede, the Netherlands (2011).
3. Skaland I et al: Evaluation of five different labeled polymer immunohistochemical detection systems. Appl Immunohistochem Mol Morphol 18:90-6 (2010).
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This information is subject to change without notice.
© Agilent Technologies, Inc. 2021 Published in the USA, April 13, 2021 29296 2021MAR18 - US Version
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