VisualSonics VEVO Operator's Manual

VisualSonics

TM

Vevo

Operator Manual

Compact Anesthesia System

VisualSonics
Vevo Compact Anesthesia System

Operator Manual

November 2003

V1.0 VisualSonics Vevo Compact Anesthesia System Operator Manual i

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

VS-OM-AS revision 1.0

VisualSonics Inc.
3080 Yonge Street, Suite 6020
Box 89
Toronto, Ontario
CANADA
M4N 3N1

Tel: [phone]
Toll Free: 1-866-416-4636
Fax: [phone]

www.visualsonics.com

Copyright © 2003 by VisualSonics Inc.
All Rights Reserved
Printed in Canada

VisualSonics, the VisualSonics logo, Vevo, and Vevo Compact Anesthesia
System are trademarks of VisualSonics Inc.

All other trademarks are the property of their respective owners.

ii VisualSonics Vevo Compact Anesthesia System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Safety

Please read the safety information before using the Vevo Compact
Anesthesia System. The following information applies to the Vevo
Compact Anesthesia System and its modules.

The use of this equipment must be directed by, is intended for use by, and
under the supervision of qualified research scientists.

Read all warnings and cautions carefully before use!

Warnings are precautions necessary to prevent injury
or loss of life.

Cautions are precautions necessary to protect the equipment.

WARNINGS

• For small animal use only. Not for human use.

• Do not fill the vaporizer with any anesthetic agent other than the one
specified on the front label. The vaporizer is designed for that agent
only. Any other agent than that specified can prove to be dangerous
to a subject.

• If a vaporizer is filled with the wrong agent, draining will not
eliminate the agent since some of the agent will have been absorbed
into the wick. The wick must be thoroughly cleaned and dried. This
procedure must be performed at an authorized service center.

• Do not carry the vaporizer by the control dial.

• Do not modify, tamper with, or disassemble the vaporizer. There is a
potential danger of damaging the vaporizer and altering the
calibration accuracy.

• Do not immerse the vaporizer in any liquid, including water.

• Do not sterilize the vaporizer.

• Do not drain the anesthetic agent into any container other than a
properly marked container.

• Incomplete sealing of the fill cap will result in loss of gases.

V1.0 VisualSonics Vevo Compact Anesthesia System Operator Manual iii

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

• Do not fill the vaporizer unless the control dial is in the ‘Off’ position.

• Do not turn the dial ‘On’ during filling or attempt to fill beyond the
‘Full’ mark.

• Keep the vaporizer upright at all times.

• Never tilt a calibrated vaporizer beyond 45 degrees when charged.
Dangerous overdose may result during subsequent use. This
condition can be detected by calibration verification only.

• Do not connect the vaporizer directly into the patient breathing
circuit.

• Do not turn on two vaporizers at the same time.

• Do not put water or any other solvent in a vaporizer.

• Due to the wick’s capacity to absorb agent, the vaporizer will
continue to deliver the set concentration for a considerable period of
time even if no liquid level can be viewed through the sight window.
However, do not use a vaporizer in this condition on a subject.

• Flush flows through an open vaporizer may result in unwanted
concentrations of anesthetic agent.

• Do not ignore maintenance of your vaporizer. An annual calibration
recertification is highly recommended by the manufacturer.

CAUTIONS

• Personnel operating this compact anesthesia system must be
thoroughly familiar with the instruction manual and equipment
operation prior to use with subjects.

• Tampering with the anesthesia system components by unauthorized
personnel voids all warranties and specifications. The prevention of
tampering with the anesthesia system is the sole responsibility of the
user or owner. VisualSonics assumes no liability for any malfunction,
failure, damage or loss to either equipment or life.

• Before using the anesthesia system check that it is set up properly,
ensure all connections and settings are correct.

• Always adhere to proper Diameter Index Safety System (D.I.S.S.)
hose connections. Failure to comply will void your warranty and
could compromise subject safety.

• Remove the machine from service if:

a. the oxygen flush button does not immediately return to the OFF

position after being released, or

b. the flow of oxygen does not immediately stop flowing from the

common outlet after the oxygen flush button is released.

Then call VisualSonics or a VisualSonics-authorized service
facility to repair the valve.

iv VisualSonics Vevo Compact Anesthesia System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

• If the oxygen flush button does not immediately return to the off
position after being released, or if the flow of oxygen does not
immediately stop flowing from the common outlet after the oxygen

flush button is released, remove the machine from service. Have the
valve repaired by VisualSonics or a VisualSonics-authorized service
facility before using the machine.

• When you turn off the flowmeter, turn the control knob clockwise
just far enough so the ball float reaches the bottom of the tube.
Continuing to tighten the control knob will damage the valve seat
and cause a leak. The unit will need to be replaced when this damage
occurs.

• Vaporizer should be serviced by an authorized service center.

• Turn the vaporizer ‘Off’ when not in use.

• A vaporizer MUST be in a vertical upright position to indicate liquid
agent levels accurately.

• If a screw-cap filler vaporizer is pressurized, turn the screw slowly
before filling.

• The delivered concentration may be different from the set
concentration if the vaporizer is operated in a tilted position.

• Avoid kinks in the tubing that will restrict flow. Eliminate leaks that
will affect total flow to the subject.

• To fill the vaporizer when in use, it will be necessary to turn the
vaporizer off.

Liability notice

• No repair should ever be undertaken or attempted by anyone not
having the training and qualifications to perform these tasks.

Failure to follow the conditions set forth below shall limit, to the extent
allowed by law, VisualSonics Inc’s responsibility for the safety, reliability,
and performance of this equipment:

• Personnel operating this compact anesthesia system must be
thoroughly familiar with the operator manual and equipment
operation prior to use with subjects.

• Tampering with the anesthesia system components by unauthorized
personnel voids all warranties and specifications. The prevention of
tampering with the anesthesia system is the sole responsibility of the
user or owner. VisualSonics assumes no liability for any malfunction,
failure, damage or loss to either equipment or life.

• Always adhere to proper Diameter Index Safety System (D.I.S.S.)
hose connections. Failure to comply will void your warranty and
could compromise subject safety.

V1.0 VisualSonics Vevo Compact Anesthesia System Operator Manual v

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

• This equipment must be periodically checked, calibrated, maintained
and, components repaired and replaced when necessary for
equipment to operate reliably. Parts that have failed in whole or in
part, exhibit excessive wear, are contaminated or are otherwise unfit
for use, should be immediately discarded and replaced. To maintain

the warranty, replacement parts must be installed or approved by
VisualSonics Inc. Equipment that is not functioning correctly must
not be used. This equipment must not be modified by unauthorized
personnel or with unauthorized components.

vi VisualSonics Vevo Compact Anesthesia System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Contents

:

Introduction

Welcome .................................................................................................. 1

Product description................................................................................1

Table-top and mobile configurations ..................................................1

Chapter 1: Unpacking the System

Unpacking the table-top configuration............................................... 3

Unpacking the mobile configuration...................................................5

Chapter 2: Installing the System

Choosing a location for the system...................................................... 9

Installation overview ............................................................................. 9

Assembling the delivery sub-system...................................................9

Connecting the delivery sub-system to the vaporizer sub-system10

Connecting the oxygen supply to the vaporizer sub-system......... 11

Troubleshooting....................................................................................14

Chapter 3: Theory of Operation

System capability..................................................................................15

Theory of operation.............................................................................. 15

Chapter 4: Operating the Vaporizer

Principle of operation ..........................................................................17

Turning on the vaporizer .................................................................... 18

Filling the vaporizer.............................................................................19

Draining the vaporizer ........................................................................ 20

Reminders for filling and draining.................................................... 21

V1.0 VisualSonics Vevo Compact Anesthesia System Operator Manual vii

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Chapter 5: Anesthetizing a Mouse

Pre-operative checks ............................................................................23

Inducing anesthesia .............................................................................23

:

Chapter 6: Service

Maintenance..........................................................................................27

VisualSonics support ........................................................................... 28

Appendix A: Accessories

Accessories for the compact anesthesia system............................... 29

Appendix B: Specifications and Performance

Specifications.........................................................................................31

Performance effects of variables......................................................... 32

Index....................................................................................................... 35

viii VisualSonics Vevo Compact Anesthesia System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Introduction

Introduction

Welcome Thank you for choosing the Vevo™ Compact Anesthesia System, the

Visualsonics’ anesthesia solution for small animals, such as mice.

Product description The Vevo Compact Anesthesia System integrates two sub-systems: a

vaporizer sub-system and a delivery sub-system.

Vaporizer sub-system The vaporizer sub- system mixes oxygen and anesthesia into a vapor. It

features a stand assembly with oxygen flowmeter, oxygen flush valve,
precision vaporizer and a 10-foot oxygen hose assembly with threaded
DISS (Diameter Index Safety System) connections.

Delivery sub-system The delivery system supplies the metabolic and anesthetic gas mixture to

the mouse. It features a dual breathing circuit that includes a 2-liter
induction chamber breathing circuit, a mouse mask breathing circuit, and
two activated charcoal filters for waste gas removal.

The system is also designed to function as a companion to the Vevo
Integrated Rail System and the Vevo 660™ High Resolution System to
provide an efficient and complete mouse imaging workspace.

Table-top and mobile
configurations

Table-top vaporizer sub­system configuration

The Vevo Compact Anesthesia System is offered in two system
configurations: a table-top configuration and a mobile configuration.

The compact and versatile table-top sub-system features a tiny footprint
of 8” x 11”, making it easy to integrate into existing lab counter space. The
sub-system includes weight-balanced handles and non-skid feet so you
can set it in place anywhere - quickly, safely and securely.

Oxygen
flowmeter

Flow
control
knob

Oxygen flush

Carrying
handles

Vaporizer
dial

Vaporizer

Common
outlet

V1.0 VisualSonics Vevo Integrated Rail System Operator Manual 1

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Introduction

Mobile vaporizer sub­system configuration

The mobile system features sturdy casters, a built-in handle so you can
move it easily to another room or another building, a convenient syringe
holder, and a stainless steel shelf that gives you a handy workspace. All
internal connections are housed in a smooth panel so you can clean the
system easily.

Vaporizer
dial

Syringe
holder

Oxygen
flowmeter

Flow
control
knob

Oxygen
flush

Stainless steel
shelf

Handle/
hanger

Vaporizer

Common
outlet

Common delivery sub­system

The delivery sub-system is a single configuration that functions
identically with each vaporizer sub-system configuration.

Mouse mask

Y-tube

Mouse mask
(waste gas - out)

Anesthesia - in

Stopcocks

Induction chamber

Charcoal filter

Induction chamber
(waste gas - out)

2 VisualSonics Vevo Integrated Rail System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Chapter 1: Unpacking the System: Unpacking the table-top configuration

Chapter 1: Unpacking the System

Unpacking the table­top configuration

Pre-assembled vaporizer
sub-system

Oxygen
flowmeter

If you ordered the table-top configuration of the compact anesthesia
system (Part # SA-TABLEANES), the crate will include the items listed
below. Please use the forms below to confirm that you have received the
included items.

The vaporizer sub-system is pre-assembled as shown below.

Isoflurane
Vaporizer
with pin­index

Common
outlet

Oxygen
flush

The vaporizer sub-system for the table-top configuration includes the
following items:

Check Quantity/unit Description

1 each Oxygen flowmeter (see photo above)

1 each Oxygen flush (see photo above)

1 each Isoflurane vaporizer with pin-index (see

photo above)

1 each Inlet and outlet (pre assembled on the

vaporizer)

V1.0 VisualSonics Vevo Compact Anesthesia System Operator Manual 3

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Chapter 1: Unpacking the System: Unpacking the table-top configuration

1 each Pin-index fill device

1 each Green 10’ oxygen hose DISS x DISS

Unassembled delivery sub­system for the table-top
configuration

The delivery sub-system is unassembled and includes the following
items:

Check Quantity/unit Description

1 each Y-tube with 15x6mm adapter, 9mm mouse

mask with 12” wastegas flexhose for
mousemask, 48” silicone tubing from
stopcock to adapter, and 30” of 22mm semi­transparent tubing

1 each 2-liter induction chamber

4 VisualSonics Vevo Compact Anesthesia System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

2 each Activated charcoal canister

Chapter 1: Unpacking the System: Unpacking the mobile configuration

Check Quantity/unit Description

1 each 22mm tubing (2-feet length)

1 each Monitoring badge

Unpacking the
mobile configuration

Pre-assembled vaporizer
sub-system

Syringe
holder

Oxygen
flowmeter

If you ordered the mobile configuration of the compact anesthesia system
(Part # SA-MOBILEANES), the crate will include the items listed below:

The vaporizer sub-system is pre-assembled as shown below:

Front view Rear view

Handle /
hanger

Isoflurane
Vaporizer

Oxygen
flush

with pin­index

Common
outlet

Oxygen
inlet

The vaporizer sub-system for the mobile configuration includes:

Check Quantity/unit Description

1 each Oxygen flowmeter (see photo above)

V1.0 VisualSonics Vevo Compact Anesthesia System Operator Manual 5

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

1 each Oxygen flush (see photo above)

1 each Isoflurane vaporizer with pin-index (see

photo above)

Chapter 1: Unpacking the System: Unpacking the mobile configuration

Check Quantity/unit Description

1 each Syringe holder (see photo above)

1 each Handle/hanger (see photo above)

1 each Inlet and Outlet (pre assembled on the

1 each Pin-index fill device

1 each Green 10’ oxygen hose DISS x DISS

vaporizer)

1 each Stainless steel shelf with mounting

screws and washers

Unassembled cart legs The cart legs are unassembled and include the items listed below.

Assembly instructions for the cart legs are included with the cart leg
parts. Please follow the instructions to complete the assembly.

Check Quantity/unit Description

1 each 2 cart legs

6 VisualSonics Vevo Compact Anesthesia System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Chapter 1: Unpacking the System: Unpacking the mobile configuration

Unassembled delivery sub­system for the mobile
configuration

The delivery sub-system is unassembled and includes the following
items:

Check Quantity/unit Description

1 each Y-tube with 15x6mm adapter, 9mm mouse

mask with 12” wastegas flexhose for
mousemask, 48” silicone tubing from
stopcock to adapter, and 30” of 22mm semi­transparent tubing

1 each 2-liter Induction Chamber

2 each Activated Charcoal Canister

1 Holder for an activated charcoal canister

V1.0 VisualSonics Vevo Compact Anesthesia System Operator Manual 7

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Chapter 1: Unpacking the System: Unpacking the mobile configuration

Check Quantity/unit Description

1 each 22mm Tubing (2-feet length)

1 each Monitoring Badge

8 VisualSonics Vevo Compact Anesthesia System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Chapter 2: Installing the System: Choosing a location for the system

Chapter 2: Installing the System

Choosing a location
for the system

The Vevo Compact Anesthesia System must be situated in an
environment that ensures maximum safety for the operator and for
others working in the building. Consider these guidelines as you
determine the location for the system.

Ventilation and air flow Ensure adequate air flow and ventilation to prevent anesthesia from

being inhaled by anyone other than the intended subjects. This is a vital
requirement. Check with your jurisdiction’s occupational health and
safety authorities to determine required levels of air flow and ventilation.

Oxygen tank location Oxygen tanks should be adequately restrained to prevent damage to the

regulators, especially due to the highly pressurized nature of the
cylinders. Custom carriers are available for E-cylinders. H-cylinders
should be chained in place.

Installation overview When you have unpacked the items (and assembled the cart legs if you

ordered the mobile configuration), the installation procedure follows the
same three steps for each configuration:

1. Assemble the delivery sub-system.

2. Connect the delivery sub-system to the vaporizer sub-system.

3. Connect the oxygen supply to the vaporizer sub-system.

Assembling the
delivery sub-system

The delivery sub-system manages the delivery and evacuation of
anesthesia to the two breathing circuits. Assembling the delivery sub­system takes approximately five to ten minutes to complete. A completed
delivery sub-system is shown below.

Mouse mask

Y-tube

Mouse mask
(waste gas - out)

Anesthesia - in

Stopcocks

Induction chamber

Charcoal filter

Induction chamber
(waste gas - out)

V1.0 VisualSonics Vevo Compact Anesthesia System Operator Manual 9

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Chapter 2: Installing the System: Connecting the delivery sub-system to the vaporizer sub-system

f

f

To assemble the induction chamber breathing circuit:

1. Insert one branch of the Y-tube into the

induction chamber port you have chosen to
receive the anesthesia. It doesn’t matter which
port you choose, left or right. Likely you will
want to choose the port that is closest to the
vaporizer system.

2. Insert a length of semi-transparent

flexhose over the second induction chamber
port. This will serve as the waste gas
evacuation port.

3. Insert one of the charcoal filters into the

flexhose.

To assemble the mouse mask breathing circuit

1. Insert one branch of the Y-tube into the 15mm (larger) end of the

15x6mm adapter.

2. Insert the anesthesia line of the mouse mask into the 6mm (smaller)

end of the 15x6mm adapter.

Use as short a length of

lexhose as is convenient. If

you need to cut the supplied

lexhose to length, cut in the
centre of the connection area,
as shown above, to ensure a
proper connection fit.

Connecting the
delivery sub-system
to the vaporizer sub­system

3. Insert the blue flexhose of the mouse mask into the 19mm (smaller)

end of the 19x22mm adapter.

4. Insert the second charcoal filter into the 22mm (larger) end of the

19x22mm adapter.

The delivery sub-system is now assembled.

The vaporizer sub-system arrives fully assembled. Now that you have
assembled the delivery sub-system, you need to connect the two sub­systems.

The connection procedure takes about five seconds.

To connect the delivery sub-system to the vaporizer sub-system:

1. Insert the Y-tube’s blue connector into the vaporizer sub-system’s

common outlet. This is a friction fit connection.

10 VisualSonics Vevo Compact Anesthesia System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

In the table-top configuration, the common outlet is located at the tip of the delivery tube.

Chapter 2: Installing the System: Connecting the oxygen supply to the vaporizer sub-system

I

n the mobile configuration, the common outlet is located on the main panel, below and to

the right of the vaporizer unit.

Connecting the
oxygen supply to the
vaporizer sub­system

Procedures for a facility
with a central oxygen
supply

This is the final assembly step. If your facility provides a regulated central
oxygen supply, the procedure will take about two minutes. If your
facility provides cylinders of compressed oxygen, you will need to
connect the appropriate VisualSonics’ factory pre-set regulator to ensure
a constant 55psi oxygen flow from the tank to the compact anesthesia
system. This adds a few minutes to the procedure.

Typically, a facility with a central
oxygen supply maintains a very large
tank of compressed oxygen situated
next to the building. Regulators at the
tank lower the pressure to a safe level

A Diameter
Index Safety
System
(D.I.S.S.)
connection.

for distribution through the facility.
The regulated oxygen is then piped
through the facility and made available through DISS connections in
various rooms and laboratories.

To connect the oxygen supply to the vaporizer sub-system:

1. Turn the fitting of one end of the green oxygen hose clockwise over

the DISS connection on the oxygen supply as shown below.

V1.0 VisualSonics Vevo Compact Anesthesia System Operator Manual 11

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Hose fitting

Tighten the hose fitting gently with an 11/16” wrench while you hold the DISS fitting
motionless with a 5/8” wrench.

DISS fitting

Chapter 2: Installing the System: Connecting the oxygen supply to the vaporizer sub-system

2. Connect the other end of the green oxygen hose to the DISS

connection on the vaporizer system using the method shown above.

The DISS connection on the table-top configuration is situated differently
than on the mobile configuration, as shown below.

Procedures for a facility
with an unregulated oxygen
supply

Tighten the hose fitting gently with an 11/16” wrench while you hold the DISS fitting
motionless with a 5/8” wrench.

Caution: The other end of the DISS hose assembly must be
connected to your tank-mounted regulator or the outlet of
your in-house 0

supply line with an operating pressure of 55

2

psi maximum. Pressure in excess of 55 psi will cause damage
to the compact anesthesia system.

Typically, a facility with an unregulated oxygen supply maintains
cylinders of compressed oxygen. E-cylinders hold approximately 651
liters of medical grade oxygen (USP) at an initial pressure of 1800 psi. H­cylinders hold approximately 7107 liters of medical grade oxygen (USP)
at an initial pressure of 2200 psi.

Factory pre-set 55 psi regulators are required for use between oxygen
cylinders and the compact anesthesia system. Factory pre-set 55 psi
regulators for E-cylinders and H-cylinders are available as accessories
from VisualSonics as detailed in “Accessories” on page 29.

12 VisualSonics Vevo Compact Anesthesia System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Chapter 2: Installing the System: Connecting the oxygen supply to the vaporizer sub-system

To connect the regulator to the oxygen tank:

1. Be sure the sealing washer is in place on the yoke inlet.

Sealing washer T-handle

2. With the valve outlet facing away from you, slightly open the oxygen

cylinder post valve to purge any undetectable debris from the valve seat,
then close the valve.

3. Slip the yoke over the cylinder post valve and fit the yoke pins into

the holes in the cylinder valve. The pins should fit easily into their
respective holes. Do not force the pins into the holes.

4. Turn the “T” handle clockwise to tighten the regulator, being sure the

“T” handle screw point is seated in the dimple on the cylinder post valve.
Tighten until secure to provide a leak-proof connection.

The oxygen supply is now ready to be connected to the vaporizer sub­system.

Remember, the outlet pressure of this pre-set regulator has been factory
pre-set. Do not attempt to re-adjust this setting.

To connect the oxygen tank to the vaporizer sub-system:

1. Connect the hose fitting of one end of the green oxygen hose to the

DISS connection on the regulator as shown below.

DISS fitting

Hose fitting

V1.0 VisualSonics Vevo Compact Anesthesia System Operator Manual 13

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Tighten the hose fitting gently with an 11/16” wrench while you hold the DISS fitting
motionless with a 5/8” wrench.

Chapter 2: Installing the System: Troubleshooting

2. Connect the oxygen supply to the mobile vaporizer sub-system or the

table-top vaporizer sub-system as described in “To connect the oxygen
supply to the vaporizer sub-system:” on page 11.

Troubleshooting

You hear a hissing sound This indicates that there is a leak in the cylinder valve, regulator to

cylinder connection, or in the regulator.

To stop the leak:

1.

Close the cylinder valve and open the regulator momentarily to

relieve all pressure.

2. Return the regulator to the off position.

3. Re-tighten the regulator to the cylinder connection and repeat the

test.

If the hissing sound continues it means that one or more of the following
conditions exist:

• The sealing washer is leaking and should be replaced. Make sure the
cylinder valve is fully turned off before removing the regulator.

• The cylinder valve is leaking. Place the cylinder outdoors and notify
the gas supplier immediately. Do not attempt to use the cylinder.

• The regulator is leaking and must be removed from service and
returned for repair. Remember to always turn the cylinder valve fully
off before removing or loosening the regulator connection.

14 VisualSonics Vevo Compact Anesthesia System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Chapter 3: Theory of Operation: System capability

Chapter 3: Theory of Operation

System capability The Vevo compact anesthesia system is designed to:

1. Change a liquid anesthetic agent into a vapor.

2. Deliver vaporized anesthesia to the subject in a precisely measured

amount.

3. Deliver a metabolic gas in addition to the anesthetic vapor, to sustain

the subject.

4. Capture all waste gas.

5. Channel waste gas to an evacuation system such as an activated

charcoal canister or a scavenging interface.

Theory of operation 1. Oxygen flows from a pressurized tank.

• The tank may be located on the anesthesia machine, in the room with
the anesthesia machine or in a remote area with the oxygen being
piped through the walls.

2. A regulator attached to the supply tank reduces oxygen pressure

from as high as 2200 psi to a usable 55 psi.

3. The oxygen flow reaches the vaporizer sub-system through the DISS

connection and is then plumbed into two channels.

a. One channel routes to the oxygen flowmeter. Use the flow

control knob on the flowmeter to reduce the 55 psi to a pressure
that produces flow measured in liters per minute (lpm).

Warning: When the oxygen flowmeter is open,
always keep one of the two stopcocks open. If you
don’t, one of the connections will break. This may
cause injury.

We recommend you choose to keep open the
stopcock to the induction chamber, because the tube
to the mouse mask is closer to the operator and if left
open, would more likely expose the operator to the
anesthetic.

b. The other channel routes to the oxygen flush valve. The normal

(closed) position prevents flow. When you press the flush button,
oxygen flows directly into the delivery sub-system at a rate of
approximately 40 lpm. This oxygen does not pass through the
vaporizer. No anesthesia is delivered.

V1.0 VisualSonics Vevo Compact Anesthesia System Operator Manual 15

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

4. Oxygen flow from the flowmeter is delivered to the vaporizer inlet.

When the vaporizer is in the “OFF” position, oxygen flows across the
vaporizer without picking up any anesthetic agent. In any other position,
vaporized anesthetic agent is delivered through the vaporizer outlet to
the delivery sub-system. The operator adjusts the vaporizer dial and

Chapter 3: Theory of Operation: Theory of operation

determines the amount of anesthetic agent vapor that will be added to the
oxygen flow. The amount is measured as a percentage of the total flow
and can be varied from 0-5%.

5. Lines from the vaporizer and the oxygen flush valve merge through

the common outlet and into the delivery sub-system.

6. Gas enters the delivery sub-system where it is bifurcated by a Y-tube

into two branches. A stopcock within each branch of the circuit provides
independent control of each branch.

a. When the stopcock to the induction chamber breathing circuit is

open, gases enter through the feed-tube. Turbulence circulates
the anesthetic gases throughout the chamber. Gases then flow
passively through flexhose evacuation tubing to a charcoal filter.

b. When the stopcock to the mouse mask breathing circuit is open,

gases flow to the mouse mask, where the subject inhales and
exhales. Gases then continue through flexhose evacuation tubing
to a charcoal filter.

Operational flowchart

Oxygen Supply

(tank or house line)

Delivery
Sub-system

Charcoal

Filter

Vaporizer Sub-system

Stopcock #1

Induction Chamber

(Subject)

Oxygen Flowmeter

+ Agent @ 0 to 4 LPM

0

2

Oxygen Flush closed:

0-4 lpm of Oxygen and

% Anesthetic Agent

02 @ 2200 PSI

Regulator

0

Hose

D.I.S.S.

(adj. 0 to 4 lpm)

0

Vaporizer

Common Outlet

Normal Flow with

Flow with Oxygen

Flush Activated:

40-5- lpm

@ 55 PSI

2

@ 0 to 4 LPM

2

Oxygen Flush Valve

(normally CLOSED)

40-50 LPM with

Flush Button

Activated

Stopcock #2

Mouse Mask

Breathing Circuit

Charcoal

Filter

16 VisualSonics Vevo Compact Anesthesia System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Subject

Chapter 4: Operating the Vaporizer: Principle of operation

Chapter 4: Operating the Vaporizer

Principle of
operation

Isoflurane Vaporizer with
pin-indexed filler

Inlet

Control dial
release button

Control dial

Outlet

Sight glass

Lower
retaining
screw

Upper
retaining
screw

Filling
tunnel

Filler
plug

Drain
valve

Draining tunnel

V1.0 VisualSonics Vevo Compact Anesthesia System Operator Manual 17

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Chapter 4: Operating the Vaporizer: Turning on the vaporizer

Vaporizer valve assembly In the ‘Off’ position, there is a direct link between the ‘inlet’ and ‘outlet’

within the vaporizer. When the dial is turned ‘On’ the carrier gas is split
into two streams: bypass and vaporizing chamber flow.

Carrier gas entering the vaporizing chamber flows through agent
saturated wicks. As the carrier gas passes through the wick, it becomes
saturated with vapor.

The amount of agent picked up in the vaporizing stream will vary due
either to variation in room temperature or to the cooling which takes
place when the agent is vaporized. Each causes changes in the effective
vapor pressures of the anesthetic agents.

Unless some form of compensating device was used, the output of the
vaporizer for a given flow and dial setting would change with
temperature.

This principle is one of many reasons explaining why it is recklessly
dangerous to use a jar and wick style vaporizer with extremely volatile
anesthetic agents such as Halothane and Isoflurane.

This vaporizer has a temperature-compensating device (thermostat) to
control the proportion of carrier gas entering the vaporizing chamber.

If the temperature of the vaporizer falls, the thermostat closes and more
carrier gas is allowed into the vaporizing chamber. If the temperature of
the vaporizer increases, the thermostat opens and less carrier gas is
allowed into the vaporizing chamber. In this way the output of the
vaporizer remains constant under conditions of changing temperature
within the clinical ranges of the vaporizer.

Turning on the
vaporizer

To turn the vaporizer On, press the control dial release button, and
simultaneously turn the control dial counter-clockwise to the desired
concentration value.

To prevent the inadvertent delivery of small concentrations, the control
dial should be turned ‘Off’ when the vaporizer is not in use.

Control dial
release button

Vaporizer in
‘Off’ position

18 VisualSonics Vevo Compact Anesthesia System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Chapter 4: Operating the Vaporizer: Filling the vaporizer

Filling the vaporizer The compact anesthesia system uses a keyed filling system to ensure

maximum safety and maximum accuracy. The keyed filling system
consists of three elements:

• the bottle collar

• the adapter

• the filling/draining unit fitted to the vaporizer

Key fill and drain systems are designed to prevent the wrong agent from
being used in the vaporizer. For example, an Isoflurane vaporizer cannot
be filled using a Halothane bottle adapter. Similarly, the Halothane bottle
adapter will not fit on the Isoflurane bottle or into the Isoflurane
vaporizer.

To fill the vaporizer:

Attach the bottle adapter to the

1.

appropriate bottle.

2. Ensure the vaporizer control is set in the

‘Off’ position.

3. Turn the top retaining screw

counterclockwise and pull out the filler plug.

4. Turn the cap slowly if the vaporizer is

pressurized.

5. Insert the keyed block of the adapter

fully into the filling tunnel, with the two
holes aimed DOWN.

• To prevent spillage, take care to bend
the tube slightly so the bottle is situated
below the inlet level.

6. Turn the retaining screw above the

filling tunnel clockwise and tighten to seal
the fill adapter in the filling tunnel.

7. Raise the bottle above the level of the

filling tunnel, without kinking the tube. A
steady stream of air bubbles should emerge
from the inner tube within two seconds.

V1.0 VisualSonics Vevo Compact Anesthesia System Operator Manual 19

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Chapter 4: Operating the Vaporizer: Draining the vaporizer

8.

When the vaporizer is filled to the ‘Full’

level, lower the bottle and remove the fill
adapter.

• If any excess liquid drains from the filler
tunnel, allow this to escape completely
before inserting and tightening the filler
plug.

Warning: Failure to replace and tighten the retaining
screw will cause gas to escape through the filler.

The vaporizer is now ready for use.

Draining the
vaporizer

Drain the vaporizer when it will be:

• transported from one location to another

•sent in for service

To drain the vaporizer:

1. Insert the fill adapter in the drain

(lower) tunnel, with the two holes aimed UP,
and then tighten the retaining screw.

2. Remove the filler plug to let air vent

from the bottle so the agent can drain. Hold
the bottle downward slightly, without
kinking the tube.

CAUTION: Turn cap slowly if vaporizer is
pressurized

3. Turn the drain valve counter-clockwise

to open it. The vaporizer will begin to drain.

20 VisualSonics Vevo Compact Anesthesia System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Chapter 4: Operating the Vaporizer: Reminders for filling and draining

4. When the draining is completed, turn

the drain valve clockwise to close it.

5. Remove the bottle adapter and replace

the filler plug in the filler tunnel. Tighten the
retaining screw (clockwise).

Warning: Failure to replace and tighten the retaining
screw will cause gas to escape through the filler.

Reminders for filling
and draining

Warning: Do not fill the vaporizer with any agent
other than the one specified on the front label. The
vaporizer is designed for that agent only. Any other
agent than that specified can prove to be dangerous
to a subject.

Warning: Do not fill the vaporizer unless the control
dial is in the ‘Off’ position.

Warning: Do not turn the dial ‘On’ during filling or
attempt to fill beyond the ‘Full’ mark.

Periodically check the agent level. The vaporizer should be refilled at
appropriate intervals. The vaporizer will function satisfactorily as long as
there is agent visible in the sight glass.

V1.0 VisualSonics Vevo Compact Anesthesia System Operator Manual 21

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

The vaporizer should be filled and used in an upright position. Small
deviations from the upright position will not affect the output or the
safety of the vaporizer.

Because the agent depth is shallow in relation to the diameter of the
vaporizing chamber, more frequent checks of the agent levels should be

Chapter 4: Operating the Vaporizer: Reminders for filling and draining

carried out when small deviations from the upright position occur. This
will prevent obtaining a misleading impression of the amount of agent in
the vaporizer.

22 VisualSonics Vevo Compact Anesthesia System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Chapter 5: Anesthetizing a Mouse: Pre-operative checks

Chapter 5: Anesthetizing a Mouse

Pre-operative checks

Verify the gas supply 1. Ensure that the oxygen supply line for each gas is connected to the

appropriate DISS inlet located on the back of the flowmeter(s). Connect
the gas supply hose(s) to the in-house supply as necessary.

2. Ensure that the gas supply is turned on.

Caution: When you turn off the flowmeter, turn the control
knob clockwise just far enough so the ball float reaches the
bottom of the tube. Continuing to tighten the control knob
will damage the valve seat and cause a leak. The unit will
need to be replaced when this damage occurs.

Test the oxygen flowmeter 3. Test the oxygen flowmeter for full range of operation by turning the

control valve counter-clockwise to open it, then clockwise to close it.
Close the valve when you have completed the test.

4. Test the oxygen flush valve for performance by pressing and holding

the button for three seconds. Oxygen should flush rapidly out of the
common outlet. When the oxygen flush button is released, it should
return immediately to the off position and the flow should stop
immediately.

Caution: Remove the machine from service if:

• the oxygen flush button does not immediately return to
the OFF position after being released, or

• the flow of oxygen does not immediately stop flowing
from the common outlet after the oxygen flush button is
released.

Then call VisualSonics or a VisualSonics-authorized service
facility to repair the valve.

Fill the vaporizer 1. Fill the vaporizer with the appropriate anesthetic agent. (See “Filling

the vaporizer” on page 19.)

Your facility should have in place an inhalation anesthesia protocol /
SOP. The following is an outline from which you can begin to create your
own. If you need assistance writing your protocol, please call us at :

1-866-416-4636.

Inducing anesthesia 1. Check that your oxygen supply tank is open and that you have

V1.0 VisualSonics Vevo Compact Anesthesia System Operator Manual 23

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

sufficient gas pressure in the line from the tank (minimum 1500 psi for E­size cylinder.

2. Assemble your system and check all connections for possible leaks of

the oxygen/anesthesia mix.

Chapter 5: Anesthetizing a Mouse: Inducing anesthesia

Connect oxygen tank to
regulator (if oxygen is
supplied from a free­standing tank)

Connect to the delivery sub­system

Connect dual delivery
system to nose cone and
chamber connection

Connect breathing elbow
down tube and chamber
outlet port to charcoal
filters

If you hear hissing:

1. Check the condition of the gasket between the tank and the regulator.

• Check the E-cylinder (651-liter tank)

• Check the H-cylinder (7107-liter tank)

2. Tighten the regulator to the tank.

Note: These checks apply to North American regulator configurations only.

This common outlet port is a friction-fit connection. Ensure that you
make leak-free connections.

These are also friction-fit connections. Again, ensure that you make leak­free connections.

Push the tubing on as tightly as possible and ensure filters are placed into
the filter holder (in an upright position). Standing filters on end impedes
the airflow out the bottom on canister, renders the filter useless and
causes back pressure in the breathing circuit.

3. If required, fill the vaporizer with the appropriate liquid agent. (See

“Filling the vaporizer” on page 19.)

4. Open the stopcock in the induction chamber tubing line.

5. Close the stopcock in the mouse mask line.

6. Turn the oxygen flowmeter to at least one (1) liter per minute (lpm).

7. Place animal #1 in the induction chamber and secure the lid.

Warning: The chamber is airtight. If the oxygen
flowmeter on the machine is turned off, there will be
NO AIRFLOW into the chamber.

NEVER leave animals in the chamber without an
oxygen flow.

8. Turn the vaporizer dial to 2-2½ %. Animal #1 should begin to lose

consciousness within two minutes.

9. When Animal #1 shows no response to rocking/jiggling the chamber

(approximately two minutes), push the oxygen flush button for 20-30
seconds (for 2-liter chamber) to evacuate all anesthesia-saturated gas
from the chamber.

Note: The brief oxygen flush evacuations of the chamber should not awaken
already anesthetized animals.

Note: If the stopcock to the mouse mask breathing circuit is open when you press
the oxygen flush button, the resulting oxygen pressure through the mouse mask
may push that animal’s nose out of the mask. Always close the stopcock to the
mouse mask before using the oxygen flush.

24 VisualSonics Vevo Compact Anesthesia System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

10. Open the stopcock in the mouse mask line.

11. Close the stopcock in the induction chamber tubing line, then

immediately open the chamber and remove Animal #1.

Chapter 5: Anesthetizing a Mouse: Inducing anesthesia

12. Place Animal #1’s nose in the mouse mask.

13. When the procedure on Animal #1 is complete, close the stopcock in

the mouse mask line and place Animal #1 in a recovery unit. That animal
will begin to awaken in approximately two minutes.

14. Repeat steps 4 through 11 with Animal #2, and all remaining models,

until all procedures have been completed.

15. Turn the vaporizer dial to the “OFF” position.

16. Turn off the oxygen flowmeter.

17. If you are using a freestanding oxygen tank, turn off the oxygen at the

tank. We also recommend you choose to keep open the Y-tube’s stopcock
to the induction chamber, and close the stopcock to the mouse mask.

18. Clean and sanitize the induction chamber and mouse mask as

outlined in your procedure area cleaning protocols.

V1.0 VisualSonics Vevo Compact Anesthesia System Operator Manual 25

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Chapter 5: Anesthetizing a Mouse: Inducing anesthesia

This page intentionally left blank.

26 VisualSonics Vevo Compact Anesthesia System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Chapter 6: Service: Maintenance

Chapter 6: Service

Maintenance Annual preventive maintenance and certification by qualified personnel

is recommended to ensure proper operation. General upkeep and daily
maintenance will enhance the longevity of your compact anesthesia
system.

Vaporizer

Warning: Do not modify, tamper with or disassemble
the vaporizer. Doing so could damage the unit and
alter the accuracy of graduation.

Observation of the operating instructions, regular servicing and normal
professional vigilance is normally all that is required to maintain the
vaporizer in a safe working condition.

Cleaning

Clean the exterior of the vaporizer with a damp cloth.

Never allow cleaning agents to accumulate in the filler, gas inlet and
outlet ports, or around the control dial.

Stand Assembly Do not use harsh or abrasive cleaners. To clean, wipe with a damp cloth.

The stand is coated with a baked-on enamel that will withstand most
cleaning/disinfectant solutions. If a solution is to be used, it is
recommended that you initially test its effect on an inconspicuous spot of
the enamel.

Flowmeter(s) Do not use harsh or abrasive cleaners. Plastic flowmeter covers may be

removed and cleaned with a damp cloth. The exterior of the glass
flowtube may be cleaned in the same manner. Should dirt or an
obstruction get inside the flowtube, contact VisualSonics for assistance.
The flow control requires no maintenance.

Oxygen Flush This valve requires no maintenance.

Rubber Goods Rubber is a natural product and will deteriorate with age and use. All

rubber goods are considered disposable and should be inspected daily for
presence, condition and alignment. DO NOT USE PETROLEUM BASED
LUBRICANTS. If you must use a lubricant, use only a silicone-based
product.

Equipment This equipment must be periodically checked, calibrated, maintained

and, components repaired and replaced when necessary for equipment to
operate reliably. Parts that have failed in whole or in part, exhibit
excessive wear, are contaminated or are otherwise unfit for use, should be
immediately discarded and replaced. To maintain the warranty,
replacement parts must be installed or approved by VisualSonics Inc.
Equipment that is not functioning correctly must not be used. This
equipment must not be modified by unauthorized personnel or with
unauthorized components.

V1.0 VisualSonics Vevo Compact Anesthesia System Operator Manual 27

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Chapter 6: Service: VisualSonics support

VisualSonics support

Annual service The vaporizer should be serviced at an authorized service center. This

service should include:

• Complete disassembly of components.

• Inspection of all parts for damage and wear.

• Thorough cleaning of all metal parts.

• Replacement of wicks, seals and damaged, worn or outdated items.

• Lubrication where necessary.

• Re-assembly of vaporizer and testing for and correction of any leaks.

• Verification of the delivered vapor concentrations under closely
defined conditions at different temperatures in order to test the
temperature compensating mechanism. Any re-graduation or
adjustment where necessary.

• Maintaining continuous service record.

Repairs Repairs should only be carried out by an authorized service center.

Note: It is not possible to change the graduation range or anesthetic agent.

If problems arise with your Vevo Compact Anesthesia System other than
the ones detailed above, we will do everything we can to ensure that your
system remains fully operational and that you experience minimum
downtime.

When such problems happen, please contact VisualSonics' Service
Department so a technical support representative can assess the nature of
the problem and help resolve it. Reach us at:

Tel: [phone]

Toll: 1-866-416-4636

[e-mail]

For minor problems, the technical support representative will walk you
through troubleshooting the situation either by phone or by e-mail,
whichever you prefer.

For more complex problems, we may send a technical support
representative to your location to evaluate the problem or we may ask
you to send the equipment to VisualSonics' Service Department for more
detailed analysis.

28 VisualSonics Vevo Compact Anesthesia System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Appendix A: Accessories

Accessories for the
compact anesthesia
system

Item Supplier

Oxygen regulator for E-cylinders VisualSonics

Oxygen regulator for H-cylinders VisualSonics

The oxygen regulator is available only in North America. Please contact
technical support for information about regulators for systems in Europe.

Appendix A: Accessories

V1.0 VisualSonics Vevo Integrated Rail System Operator Manual 29

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Appendix A: Accessories

This page intentionally left blank.

30 VisualSonics Vevo Integrated Rail System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Appendix B: Specifications and Performance

Appendix B: Specifications and Performance

Specifications All specifications are for standard systems.

Operational characteristics

Table-top system Mobile system

Controls

Flowmeter
volume

Oxygen flush
volume

0-4 liters per minute @
55 psi

15-35 liters per minute
@ 55 psi

Gas supply Oxygen male DISS

connector

Gas pressure

50-55 psi 50-55 psi

requirements

Flowmeter Single-turn metering

valve

Oxygen flush Plunger-actuated,

spring-return valve

Adjustable

None None
pressure
limiting (APL)
valve

0-4 liters per minute @
55 psi

15-35 liters per minute
@ 55 psi

Oxygen male DISS
connector

Single-turn metering
valve

Plunger-actuated,
spring-return valve

Physical properties

Calibration

V1.0 VisualSonics Vevo Integrated Rail System Operator Manual 31

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Weight Approximately 32 lbs

(14.5 kg)

Approximately 56 lbs
(25.41 kg)

Dimensions 11”w x 8”d x 14”h 19”w x 18”d x 50”h

Material Aluminum frame; steel

handle, bolts and
screws; brass valves
and tubing; acrylic
flowmeter cover

Aluminum frame; steel
bolts and screws; brass
valves and tubing;
acrylic flowmeter
cover; Delrin handle

Finish Heat-treated enamel Heat-treated enamel

Vaporizers are calibrated at 21 ºC (70 ºF) and at elevated temperatures.
The variation in output with temperature, flow rate and duration of use is

Appendix B: Specifications and Performance

small, and the variation in output when used with Intermittent Positive
Pressure Respiration is negligible.

Agent usage The rate of consumption of anesthetic agent depends primarily on flow

rate and vapor output concentration.

The rate of evaporation of anesthetic agent may, with caution, be used as
an approximate method of checking that the delivered output is not
grossly in error, and as a means of estimating how often the vaporizer is
likely to need refilling. The approximate hourly consumption of
anesthetic agents can be expressed as follows:

3 x % x F

Where % represents the setting of the vaporizer output percentage, F
represents the input flow rate in liter/min.

Example: if a vaporizer is set to deliver 2% at 6-liter/min. total input gas
flow rate:

Approximate rate of agent consumption = 3 x 2 x 6 = 36 ml/hour.

The figures are intended only for clinical guidance and are approximate.
They will vary depending upon the type of anesthetic agent employed,
accuracy of graduation of flowmeters, etc., and will be grossly in error if
the vaporizer drain port is not fully closed.

Performance effects
of variables

Temperature The effects of variation of temperature are normally negligible at

commonly used combinations of dial setting and ambient temperature.

The vaporizer responds very slowly to changes in ambient temperature
and (to prevent the valve from closing completely) as a safety feature the
temperature sensitive valve does not respond to temperatures below the
range of approximately 12 - 15 ºC (54 - 59 ºF). Should the vaporizer
temperature be lower than this, the output can be expected to be lower
than that indicated on the dial.

At temperatures above 32 ºC (90 ºF), the vaporizer output may be
unpredictably high - particularly if the temperature approaches the
boiling point of the specific anesthetic agent.

To avoid inaccuracies due to extreme temperatures, the vaporizer should
be allowed to attain a temperature of 20-32 ºC (68 - 90 ºF).

Flow The vaporizer compensates for variations in inlet flow from 300 ml to 10

liters per minute with minimal change in output concentration.
Resistance to flow within the vaporizer is minimal: 40 cm/H20 (30 mm/

Hg) at 10 liters per minute.

Carrier gas composition Small effects can occur when the carrier gas composition is changed from

oxygen to air or nitrous oxide/oxygen mixture. As a general rule,
variation of output with carrier gas composition can be considered of
negligible clinical significance since the effects, if any, are normally less
than 10% of setting. Where changes do occur, the usual effect is that the
output is slightly depressed when nitrous oxide is employed compared to

32 VisualSonics Vevo Integrated Rail System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Appendix B: Specifications and Performance

the output when oxygen is the carrier gas. The presence of nitrous oxide
reduces the required inspired concentration of volatile agent and this
mitigates this small depression in output from the vaporizer.

Time out of service If the anesthetic machine on which the vaporizer is fitted is left for a

period of time with no gases flowing, a concentration of agent may be
observable at the machine outlet when the gas flow is turned ‘On’ and the
vaporizer is turned ‘off.’ This concentration can be expected to fall
rapidly to zero (e.g. within about 15 seconds at 5 liter/min.). This
phenomenon is a normal characteristic of anesthetic vaporizers and
machines. Clinically this is normally considered to be insignificant
because of the small volume of vapor involved.

Other variables Ambient temperature, input flow rate and duration often can affect

delivered concentrations, particularly when the vaporizer is used at
extremes of the usual clinical range. The valve design and temperature
compensation system of this vaporizer reduces these effects, under most
clinical conditions, to levels that are clinically not significant.

V1.0 VisualSonics Vevo Integrated Rail System Operator Manual 33

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Appendix B: Specifications and Performance

This page intentionally left blank.

34 VisualSonics Vevo Integrated Rail System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Index

Index

A

accessories, 29
annual service, 28

C

calibration, 31
cart legs

assembling, 6
cautions, iv
choosing a location for the system, 9
compact anesthesia system

description, 1

D

delivery sub-system, 9

assembling, 9

connecting to the vaporizer sub-

system, 10

I

inducing anesthesia, 23
induction chamber breathing circuit

assembling, 10

M

mouse mask breathing circuit

assembling, 10

O

operational characteristics, 31
oxygen flowmeter

testing, 23
oxygen tank

connecting the regulator to, 13

turning on, 17, 18

vaporizer sub-system, 10

connecting oxygen supply to, 11
connecting the delivery sub-

system to, 10

W

warnings, iii

P

performance effects of variables, 32

R

regulator

available for E-cylinders and H-

cylinders, 29

connecting to the oxygen

tank, 13

handling hissing sounds, 14
repairs, 28

S

specifications, 31

T

theory of operation, 15

flowchart, 16

V

vaporizer

draining, 20

filling, 19

principle of operation, 17

V1.0 VisualSonics Vevo Compact Anesthesia System Operator Manual 35

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

Index

36 VisualSonics Vevo Compact Anesthesia System Operator Manual V1.0

Need help? Call us toll-free: 1-866-416-4636 or E-mail us: [e-mail]

VS-OM-AS revision 1.0 P/N 10860