Thermo Scientific Vanquish Charger Operating Manual
thermoscientific
Vanquish
Charger
OperatingManual
4829.0001‐ENRevision1.0a • September2017
Copyright © 2014 Thermo Fisher Scientific Inc. All rights reserved.
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Thermo Fisher Scientific Inc. provides this document to its customers with a product purchase to
use in the product operation. The document is copyright protected; any reproduction of the
whole or any part of this document is strictly prohibited, except with the written authorization
of Thermo Fisher Scientific Inc.
This manual is provided "as is." The contents of this manual are subject to being changed,
without notice, in future revisions.
Thermo Fisher Scientific Inc. makes no representations that this document is complete,
accurate, or error-free. Thermo Fisher Scientific Inc. assumes no responsibility and will not be
liable for any errors, omissions, damage, or loss that might result from any use of this document,
even if the information in the document is followed properly.
This document is not part of any sales contract between Thermo Fisher Scientific Inc. and a
purchaser. This document shall in no way govern or modify any Terms and Conditions of Sale.
The Terms and Conditions of Sale shall govern all conflicting information between the two
documents.
Release history
Revision 1.0, released in July 2014, original operating manual
The hardware descriptions in this manual revision refer to devices VH-A90-A.
Manufacturer's address
Thermo Electron LED GmbH
Robert-Bosch-Straße 1
D – 63505 Langenselbold
Printed manual version only
Printed in Germany on 100% chlorine-free bleached, high-white paper that is produced in an
environmentally friendly process, leading to a paper profile of zero CO2 emissions.
Contacting Us
Ordering Information
Technical Assistance
Contacting Us
There are several ways to contact us:
For ordering information or sales support for HPLC products, contact
your local Thermo Fisher Scientific sales organization. For contact
information, go to Contact Us on http://www.thermoscientific.com.
For technical support for HPLC products, contact your local Thermo
Fisher Scientific support organization. For contact information, go to
Contact Us on http://www.thermoscientific.com.
Vanquish Charger Operating Manual Page 3
Contacting Us
Page 4 Vanquish Charger Operating Manual
Contents
1 Using this Manual ............................................................................ 9
2 Safety ..............................................................................................15
Contents
1.1 About this Manual ................................................................................................ 10
1.2 Conventions .......................................................................................................... 11
1.2.1 Safety Messages ....................................................................................... 11
1.2.2 Special Notices and Informational Notes ................................................. 11
1.2.3 Typographical Conventions ...................................................................... 12
1.3 Reference Documentation .................................................................................... 13
2.1 Safety Symbols and Signal Words ......................................................................... 16
2.1.1 Safety Symbols and Signal Words in This Manual ................................... 16
2.1.2 Observing this Manual ............................................................................. 16
2.1.3 Safety Symbols on the Charger ................................................................ 17
2.1.4 Rating Plate/Type Label ........................................................................... 17
2.2 Intended Use ......................................................................................................... 18
2.3 Safety Precautions ................................................................................................ 19
2.3.1 General Safety Information ..................................................................... 19
2.3.2 Qualification of the Personnel ................................................................. 20
2.3.3 Personal Protective Equipment ............................................................... 20
2.3.4 Electric Safety Precautions ....................................................................... 21
2.3.5 General Residual Hazards ........................................................................ 22
2.3.6 In Case of Emergency ............................................................................... 23
2.4 Compliance Information ....................................................................................... 24
3 Charger Overview ...........................................................................25
3.1 Charger Features ................................................................................................... 26
3.2 Operating Principle ............................................................................................... 27
3.3 Interior Components............................................................................................. 28
3.3.1 LED Status Indicators ............................................................................... 29
3.3.2 Shelf ......................................................................................................... 29
3.3.3 Mover ....................................................................................................... 30
3.4 Device Connections .............................................................................................. 31
3.5 Operation .............................................................................................................. 32
Vanquish Charger Operating Manual Page 5
Contents
4 Unpacking and Transport ................................................................ 33
4.1 Unpacking and Moving ........................................................................................ 34
4.2 Scope of Delivery ................................................................................................. 36
5 Installation ...................................................................................... 37
5.1 Safety Guidelines for Installation ......................................................................... 38
5.2 Site Requirements ................................................................................................ 39
6 Operation ....................................................................................... 41
6.1 Introduction to this Chapter ................................................................................ 42
6.2 Safety Guidelines for Operation .......................................................................... 43
6.3 Control Elements.................................................................................................. 45
6.3.1 Status Indicators ...................................................................................... 45
6.3.2 Power Switch ........................................................................................... 46
6.4 Preparing the Charger for Operation ................................................................... 47
6.4.1 Temperature Control in the Charger Compartment ............................... 47
6.4.2 Loading Sample Racks or Well Plates ...................................................... 48
6.4.3 Selecting the Rack Type........................................................................... 52
6.5 Important Settings for Operation ........................................................................ 53
6.6 Shutting Down the Charger.................................................................................. 54
7 Maintenance ................................................................................... 55
7.1 Introduction to Maintenance ............................................................................... 56
7.2 Safety Guidelines for Maintenance...................................................................... 57
7.3 Routine and Preventive Maintenance ................................................................. 58
7.3.1 Maintenance Plan ................................................................................... 58
7.3.2 Cleaning the Charger ............................................................................... 59
7.4 Updating the Charger Firmware .......................................................................... 60
7.5 Transporting or Shipping the Charger .................................................................. 62
8 Troubleshooting .............................................................................. 67
8.1 General Information about Troubleshooting ...................................................... 68
8.2 Messages .............................................................................................................. 70
Page 6 Vanquish Charger Operating Manual
Contents
9 Specifications ..................................................................................73
9.1 Performance Specifications .................................................................................. 74
9.2 Physical Specifications .......................................................................................... 75
10 Accessories, Consumables and Replacement Parts ........................77
10.1 General Information ............................................................................................. 78
10.2 Ordering Information ............................................................................................ 79
11 Compliance Information ................................................................81
11.1 Declaration of Conformity .................................................................................... 82
11.2 WEEE Compliance ................................................................................................. 83
11.3 FCC Compliance .................................................................................................... 84
12 Index .............................................................................................85
Vanquish Charger Operating Manual Page 7
Contents
Page 8 Vanquish Charger Operating Manual
1 • Using this Manual
1 Using this Manual
This chapter provides information about this manual, the conventions used
throughout the manual, and the reference documentation that is available
in addition to this manual.
Vanquish Charger Operating Manual Page 9
1 • Using this Manual
1.1 About this Manual
This manual describes the functional features and operating principle of
your Vanquish™ Charger and provides instructions for installation, set
up, start up, shut down, operation, maintenance and troubleshooting.
The layout of this manual is designed to provide quick reference to the
sections of interest to the user. To obtain a full understanding of your
Charger, read this manual thoroughly.
This manual also contains safety messages, precautionary statements,
and special notices that can prevent personal injury, damage to the
Charger, or loss of data when followed properly.
Note the following:
• The Charger configuration may vary; therefore, not all descriptions
necessarily apply to your particular Charger.
• If some detail applies to only one model or variant, the model or
variant is identified by name.
• Illustrations in this manual are provided for basic understanding.
They can vary from the actual model of the Charger or component.
However, this does not influence the descriptions. No claims can be
derived from the illustrations in this manual.
Page 10 Vanquish Charger Operating Manual
1.2 Conventions
This section describes the conventions that are used throughout this
manual.
1.2.1 Safety Messages
The safety messages and precautionary statements in this manual
appear as follows:
• Safety messages or precautionary statements that apply to the
• Safety messages or precautionary statements that apply to an entire
1 • Using this Manual
entire manual and all procedures in this manual are grouped in the
Safety chapter.
section or to multiple procedures in a section appear at the
beginning of the section to which they apply.
• Safety messages that apply to only a particular section or procedure
appear in the section or procedure to which they apply. They appear
different from the main flow of text.
Safety messages are often preceded by an alert symbol and/or alert
word. The alert word appears in uppercase letters and in bold type.
Make sure that you understand and follow all safety messages
presented in this manual.
1.2.2 Special Notices and Informational Notes
Special notices and informational notes in this manual appear different
from the main flow of text. They appear in boxes and a note label
identifies them. The label text appears in uppercase letters and in bold
type.
NOTICE Highlights information necessary to prevent damage to the
Charger or invalid test results.
TIP Highlights information of general interest or helpful information that
can make a task easier or optimize the performance of the Charger.
Vanquish Charger Operating Manual Page 11
1 • Using this Manual
1.2.3 Typographical Conventions
These typographical conventions apply to the descriptions in this
manual:
Data Input and Output
• The following appears in bold type:
♦ Input that you enter by the keyboard or that you select with the
mouse
♦ Buttons that you click on the screen
♦ Commands that you enter by the keyboard
♦ Names of, for example, dialog boxes, properties, and parameters
• For brevity, long expressions and paths appear in the condensed
form, for example: Click Start > All Programs > Chromeleon 7 >
Services Manager > Start Instrument Controller.
References and Messages
• References to additional documentation appear italicized.
• Messages that appear on the screen are identified by quotation
marks.
Viewpoint
If not otherwise stated, the expressions left and right in this manual
always refer to the viewpoint of a person that is facing the Charger from
the front.
Particularly Important Words
Particularly important words in the main flow of text appear italicized.
Electronic Manual Version (PDF)
The electronic version (PDF) of the manual contains numerous links that
you can click to go to other locations within the manual. These include:
• Table of contents entries
• Index entries
• Cross-references (in blue text), for example, to sections and figures
Page 12 Vanquish Charger Operating Manual
1.3 Reference Documentation
In addition to this operating manual, other documentation is available
for reference.
Hardware Documentation
Additional hardware documentation includes the following:
• Operating manuals for the other modules of the Vanquish system
A printed version of the manual is shipped with the device.
• Vanquish System Operating Manual
A printed version of the manual is shipped with the Vanquish system
base and solvent rack.
• Instrument Installation Qualification Operating Manual
1 • Using this Manual
TIP Electronic versions of these manuals are available as PDF (Portable
Document Format) files. To open and read the PDF files, Adobe®
Reader® or Adobe® Acrobat® is required.
Software Documentation
Additional software documentation includes the following:
• Chromeleon™ 7 Help and documents
The Chromeleon 7 Help provides extensive information and
comprehensive reference material for all aspects of the software.
For basic information about device installation and configuration,
refer to the Installation Guide; for specific information about a
certain device, refer to the Instrument Configuration Manager Help.
In Chromeleon 7, devices are called modules.
For information about the main elements of the user interface and
step-by-step guidance through the most important workflows, refer
to the Quick Start Guide.
For a concise overview of the most important workflows, refer to
the Reference Card.
Vanquish Charger Operating Manual Page 13
1 • Using this Manual
Third-Party Documentation
• Chromeleon™ 6.8 Help
The Chromeleon 6.8 Help provides extensive information for all
aspects of the software, including device installation and
configuration.
TIP The Chromeleon Help and documents are included in the software
shipment.
Refer also to the user documentation provided by the manufacturers of
third-party components and materials, for example, Material Safety
Data Sheets (MSDSs).
Page 14 Vanquish Charger Operating Manual
2 • Safety
2 Safety
This chapter provides general and specific safety information and informs
about the intended use of the Charger.
Vanquish Charger Operating Manual Page 15
2 • Safety
2.1 Safety Symbols and Signal Words
2.1.1 Safety Symbols and Signal Words in This Manual
This manual contains safety messages to prevent injury of the persons
using the Charger. The safety symbols and signal words in this manual
include the following:
Always be aware of the safety information. Do not proceed until you
have fully understood the information and consider the consequences of
what you are doing.
CAUTION Indicates a hazardous situation that, if not avoided, could
result in minor or moderate injury.
WARNING Indicates a hazardous situation that, if not avoided, could
result in serious injury.
2.1.2 Observing this Manual
Observe the following:
• Before installing or operating the Charger, read this manual carefully
to be familiar with the Charger and this manual. The manual
contains important information with regard to user safety as well as
use and care of the Charger.
• Always keep the manual near the Charger for quick reference.
• Save this manual and pass it on to any subsequent user.
Read, understand, and comply with all safety messages and
precautionary statements presented in this manual.
Page 16 Vanquish Charger Operating Manual
2.1.3 Safety Symbols on the Charger
The table lists the safety symbols that appear on the Charger or on
labels affixed to the Charger. Follow the safety notices in this manual to
prevent the risk of operator injury or damage to the Charger.
Symbol Description
Indicates a potential hazard. Refer to this manual to avoid the risk of
personal injury and/or to prevent damage to the device.
2 • Safety
Ο
2.1.4 Rating Plate/Type Label
The rating plate/type label is present behind the Charger front door, on
the left-hand side. The rating plate indicates the serial number, part
number, line rating, and the manufacturer's address.
Power supply is on
Power supply is off
Indicates that the high LED output (according to IEC 62471:2006)
produced by the barcode reader in the device may be harmful to the
eyes. Do not use light-focusing instruments for viewing the light
output.
Indicates that liquid reservoirs or any other items must not be placed
on top of the Charger.
Indicates that sample racks and well plates must be placed with
position A1 in the front right corner.
An additional label on the left-hand side of the Charger near the
electrical connections indicates the fuse and line rating.
Vanquish Charger Operating Manual Page 17
2 • Safety
2.2 Intended Use
The Charger is intended to be part of the Vanquish system. The intended
use of the Vanquish system is to analyze a mixture of compounds in
sample solutions. The Charger is for use by qualified personnel and in
laboratory environment only.
The Charger and Vanquish system are intended for laboratory research
use only. They are not intended for use in diagnostic procedures.
Laboratory Practice
Thermo Fisher Scientific recommends that the laboratory in which the
Vanquish system is used follow best practices for LC analyses. This
includes among others:
• Using appropriate standards
• Regularly running calibration prior to reporting results
• Establishing shelf life limits and following them for all consumables
used with the system
• Running the system according to the laboratory's verified and
validated 'lab developed test' protocol
Page 18 Vanquish Charger Operating Manual
2.3 Safety Precautions
2.3.1 General Safety Information
All users must observe the general safety information presented in this
section and all specific safety messages and precautionary statements
elsewhere in this manual during all phases of installation, operation,
troubleshooting, maintenance, shutdown, and transport of the Charger.
If the Charger is used in a manner not specified by Thermo Fisher
Scientific, the protection provided by the Charger could be impaired.
Observe the following:
• Operate the Charger only within its technical specifications.
• Use only the replacement parts and additional components, options,
and peripherals specifically authorized and qualified for the Charger
by Thermo Fisher Scientific.
2 • Safety
Safety Standard
• Thermo Fisher Scientific cannot be held liable for any damage,
material or otherwise, resulting from inappropriate or improper use
of the Charger. If there is any question regarding appropriate usage,
contact Thermo Fisher Scientific before proceeding.
This device is a Safety Class I instrument (provided with terminal for
protective grounding). The device has been manufactured and tested
according to international safety standards.
Vanquish Charger Operating Manual Page 19
2 • Safety
2.3.2 Qualification of the Personnel
Observe the information below on the proper qualification of the
personnel installing and/or operating the Charger.
Installation by Service Engineer only
Service personnel certified by Thermo Fisher Scientific must perform the
installation (for brevity, referred to as Thermo Fisher Scientific service
engineer).
General Operation
The Charger is designed to be operated only by trained and qualified
personnel in a laboratory environment.
All users must know the hazards presented by the Charger and the
substances they are using. All users should observe the related Material
Safety Data Sheets (MSDSs).
Instruction of the Operating Personnel
For any operation of this device, the operator must prepare clear and
concise written instructions in the language of the operating and
cleaning personnel based on this operating manual, applicable safety
data sheets, plant hygiene guidelines, and technical regulations.
2.3.3 Personal Protective Equipment
Wear personal protective equipment and follow good laboratory
practice to protect you from hazardous substances. The appropriate
equipment depends on the hazard. For advice on the hazards and the
equipment required for the substances you are using, refer to the
material handling and safety data sheet provided by the vendor.
An eyewash facility and a sink should be available nearby. If any
substance contacts your skin or eyes, wash the affected area and seek
medical attention.
Page 20 Vanquish Charger Operating Manual
Protective Clothing
Protective Eyewear
Gloves
2 • Safety
To protect you from chemical splashes, harmful liquids, or other
contamination, put on appropriate protective clothing, such as a lab
coat.
To prevent liquids from striking your eyes, put on appropriate protective
eyewear, such as safety glasses with side shields. If there is a risk of
splashing liquids, put on goggles.
To protect you from harmful liquids and avoid personal injury during
maintenance or service, put on appropriate protective gloves.
2.3.4 Electric Safety Precautions
WARNING— Electric Shock or Damage to the Device
High voltages are present inside the device that could cause an electric
shock or damage to the device.
• Do not make any changes to the electrical or grounding connections.
• If you suspect any kind of electrical damage, disconnect the power
cord and contact Thermo Fisher Scientific Technical Support for
assistance.
• Do not open the housing or remove protective panels unless
specifically instructed to do so in this manual.
• Do not place liquid reservoirs directly upon the device. Liquid might
leak into the device and get into contact with electronic components
causing a short circuit. Instead, place liquid reservoirs in the solvent
rack that is available for the Vanquish system.
Vanquish Charger Operating Manual Page 21
2 • Safety
2.3.5 General Residual Hazards
Pay attention to the following general residual hazards when working
with the Charger:
WARNING—Hazardous Substances
Solvents, mobiles phases, samples, and reagents might contain toxic,
carcinogenic, mutagenic, infectious, or otherwise harmful substances.
The handling of these substances can pose health and safety risks.
• Be sure that you know the properties of all substances that you are
using. Avoid exposure to harmful substances. If you have any doubt
about a substance, handle the substance as if it is potentially
harmful.
• Wear personal protective equipment as required by the hazard and
follow good laboratory practice.
• Reduce the volume of substances to the minimum volume required
for sample analysis.
• Do not operate the Charger in a potentially flammable environment.
• Avoid accumulation of harmful substances. Make sure that the
installation site is well ventilated.
• Dispose of hazardous waste in an environmentally safe manner that
is consistent with local regulations. Follow a regulated, approved
waste disposal program.
WARNING—Biohazard
Human-sourced material, for example microorganisms, cell cultures,
tissues, body fluids, and other biological agents can transmit infectious
diseases. To avoid infections with these agents:
• Assume that all biological substances are at least potentially
infectious.
• Wear personal protective equipment as required by the hazard and
follow good laboratory practice.
• Dispose of bio-hazardous waste in an environmentally safe manner
that is consistent with local regulations. Follow a regulated,
approved waste disposal program.
Page 22 Vanquish Charger Operating Manual
2 • Safety
WARNING—Hazardous Gases
Mobiles phases and samples might contain volatile or flammable
solvents. The handling of these substances can pose health and safety
risks.
• Avoid accumulation of these substances. Make sure that the
installation site is well ventilated.
• Avoid open flames and sparks. Do not operate the Charger in the
presence of flammable gases or fumes.
WARNING—Flammable and Hazardous Vapors
Flammable or hazardous vapors can escape from improperly sealed
sample containers with flammable or volatile samples, and can
accumulate inside the device. This can pose health and safety risks and
lead to wrong results.
Observe the following safety guidelines with flammable and volatile
samples:
• Use only vials or well plates that are made gas-tight by means of
caps, sealing mats, or sealing tapes. Refer to the latest list of closures
approved by Thermo Fisher Scientific.
• Inspect vials for cracks or defects before use. Do not use cracked or
damaged vials.
WARNING—Explosion Hazard
The air gap in the door seal of the Charger is an engineered safety
feature designed to provide adequate air exchange inside the Charger.
Do not block or modify this port for any reason. Blocking this port may
result in the build-up of vapors inside the unit that can result in an
explosion hazard.
2.3.6 In Case of Emergency
WARNING—Safety Hazard
In case of emergency, disconnect the Charger from the power line.
Vanquish Charger Operating Manual Page 23
2 • Safety
2.4 Compliance Information
Thermo Fisher Scientific performs complete testing and evaluation of its
products to ensure full compliance with applicable domestic and
international regulations. When the device is delivered to you, it meets
all pertinent electromagnetic compatibility (EMC) and safety standards
as described in this manual. For details, see section 11, page 81.
Changes that you make to the device may void compliance with one or
more of these EMC and safety standards. Changes to the device include
replacing a part or adding components, options, or peripherals not
specifically authorized and qualified for the product by Thermo Fisher
Scientific. To ensure continued compliance with EMC and safety
standards, replacement parts and additional components, options, and
peripherals must be ordered from Thermo Fisher Scientific or one of its
authorized representatives.
The device has been shipped from the manufacturing site in a safe
condition.
Page 24 Vanquish Charger Operating Manual
3 • Charger Overview
3 Charger Overview
This chapter introduces you to the Charger and the main components.
Vanquish Charger Operating Manual Page 25
3 • Charger Overview
3.1 Charger Features
The Charger stores sample racks and well plates during an analysis, and
transfers them to the Vanquish autosampler. It includes the following
features:
• A shelf to store sample racks and well plates. Different shelves are
available for sample racks and well plates of variable heights.
• A mover to transport sample racks and well plates from their
position in the shelf to the autosampler carousel and vice versa.
• A temperature control and airflow system to ensure that the
temperature within the compartment remains at a set temperature,
such that samples can be stored at suitable thermal conditions.
• A barcode reader to identify barcode-labeled Vanquish sample racks
and well plates in the shelf as well as empty shelf positions.
• A sensor to detect if a sample rack or well plate is present on the
shovel to prevent the double loading of the shelf, for example, after
a power reset.
• An active evaporation system to collect condensation. In case of
excessive temperature fluctuations (while cooling and at
compartment temperatures below ambient temperature), moisture
may condense on the compartment surfaces. To prevent the
samples from being humidified, a condensate collector tray traps
the condensate and the moisture evaporates from the tray.
• The Charger is designed to be controlled by the Chromeleon
Chromatography Data Management System.
Page 26 Vanquish Charger Operating Manual
3.2 Operating Principle
The mover is the transport system of the Charger. The mover shovel
transports sample racks and well plates from the shelf to the free
position in the yellow (Y) segment in the autosampler carousel through a
transfer opening in the right Charger side panel. In the same way, the
mover shovel transports the sample racks and well plates from the
autosampler segment Y back into their target position in the shelf.
The picture illustrates how the mover operates:
3 • Charger Overview
Figure 1: Operating principle
No. Description
1 Shelf with sample racks and/or well plates (here: deep well plates)
2 Deep well plate being transported
3 Mover
4 Autosampler carousel – the yellow segment (Y) is used for sample racks and
well plates delivered from the Charger
Vanquish Charger Operating Manual Page 27
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