Thermo Scientific Heraeus Multifuge 4KR Instruction Manual
Thermo Scientific
Heraeus Multifuge 4KR
Instruction Manual
20057761-c 08 / 2014
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Original instruction manual 20057760-c printed in 08 / 2014.
Instruction manual 20057761-c is a translation of 20057760-c.
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documentation:
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: Labor-Zentrifuge
: Multifuqe
:75004461
:41318912
machinery 2006/42/EC.
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4KR
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(€
ist.
Die Maschine ist auch in Übereinstimmung
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The machinery
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Die Schutzziele
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The
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EN 61010-1:2004
EN 61010-2-020:2006
EN 61326-1:2006
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WEEE Conformity
This product is subject to the regulations of the EU Waste Electrical & Electronic Equipment
(WEEE) Directive 2002/96. It is marked by the following symbol:
Thermo Fisher Scientific has entered into agreements with recycling and disposal companies in all EU
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T
Table of Contents
Preface .......................................................................................................................................iii
Scope of Supply .......................................................................................................................iii
Intended Use ..............................................................................................................................iv
Accident Prevention .................................................................................................................iv
Precautions .................................................................................................................................v
Chapter 1 Introduction and Description ............................................................................................... 1-1
Characteristics of the Heraeus Multifuge 4KR ......................................................... 1-2
Technical Data ........................................................................................................ 1-3
Directives, Standards and Guidelines ...................................................................................... 1-3
Functions and Features ............................................................................................................ 1-4
Mains Supply ........................................................................................................... 1-5
Rotor Selection ........................................................................................................ 1-5
Chapter 2 Before Use ............................................................................................................................... 2-1
Before Setting up ..................................................................................................... 2-2
Location .................................................................................................................. 2-2
Setting up ................................................................................................................ 2-2
Transporting the Centrifuge .................................................................................... 2-3
Mains Connection ................................................................................................... 2-4
Storage ..................................................................................................................... 2-4
Chapter 3 Control Panel .......................................................................................................................... 3-1
Control Panel .......................................................................................................... 3-2
Keys ......................................................................................................................... 3-2
Chapter 4 Operation .................................................................................................................................4-1
Switch on Centrifuge ............................................................................................... 4-2
Centrifuge Door ..................................................................................................... 4-2
Rotor Installation ..................................................................................................... 4-3
Entering Parameters ................................................................................................. 4-4
Centrifugation ......................................................................................................... 4-8
Temperature Adaptation during Standstill ............................................................... 4-9
Short-term Centrifugation ....................................................................................... 4-9
Removing the Rotor ................................................................................................ 4-9
Aligning the Centrifuge ......................................................................................... 4-10
Audible Alarm ....................................................................................................... 4-10
Key Switch ............................................................................................................. 4-11
Chapter 5 Maintenance and Care .........................................................................................................5-1
Cleaning Intervals .................................................................................................... 5-2
Cleaning .................................................................................................................. 5-2
Cleaning the Venting Slots ...................................................................................... 5-3
Thermo Scientific Multifuge 4KR i
Contents
Disinfection ............................................................................................................. 5-4
Decontamination ..................................................................................................... 5-4
Service of Thermo Fisher Scientific .......................................................................... 5-5
Shipping and deposing of accessories ....................................................................... 5-6
Chapter 6 Troubleshooting .....................................................................................................................6-1
Mechanical Emergency Door Release ...................................................................... 6-2
Troubleshooting by User ......................................................................................... 6-3
When to contact a Service Technician ..................................................................... 6-5
Chemical Compatibility Chart ..............................................................................A-1
Contact Information ................................................................................................B-1
ii Multifuge 4KR Thermo Scientific
P
Preface
Before starting to use the centrifuge, read through this instruction manual carefully and follow the
instructions.
The information contained in this instruction manual is the property of Thermo Fisher Scientific; it is
forbidden to copy or pass on this information without explicit approval.
Failure to follow the instructions and safety information in this instruction manual will result in the
expiration of the sellers warranty.
Scope of Supply
Article Number Quantity Check
75004461 Heraeus Multifuge 4KR Centrifuge 1
Power supply cable 1
20360073 Allen wrench 1
50127698 CD with manual 1
If any parts are missing, please contact your nearest Thermo Fisher Scientific representative.
This symbol refers to general hazards.
CAUTION means that material damage could occur.
WARNING means that injuries or material damage or contamination could occur.
This symbol refers to biological hazards.
Observe the information contained in the instruction manual to keep yourself and your
environment safe.
Thermo Scientific Heraeus Multifuge 4KR iii
P Intended Use
g
cm
3
---------- -
Intended Use
• This centrifuge is a laboratory product designed to separate components by generation of a
relative centrifugal force. It separates human samples (e.g. blood, urine and other body fluids)
collected in appropriate containers, either alone or after addition of reagents or other additives.
This symbol means that both castor breaks must
be closed before the run.
• Laboratory centrifuge for the application in large laboratories, blood banks, and other the sector
of the pharmaceutical and bio-technological industry.
• The centrifuge is to be used for separating materials of different density or particle size
suspended in a liquid.
Maximum sample density at maximum speed: 1.2
Accident Prevention
Prerequisite for the safe operation of the Heraeus Multifuge 4KR is a work environment in
compliance with standards, directives and trade association safety regulations and proper
instruction of the user.
The safety regulations contain the following basic recommendations:
• Maintain a radius of at least 30 cm around the centrifuge.
• Implementation of special measures which ensure that no one can approach the
centrifuge for longer than absolutely necessary while it is running.
• The mains plug must be freely accessible at all times. Pull out the power supply plug or
disconnect the power supply in an emergency.
iv Heraeus Multifuge 4KR Thermo Scientific
Precautions
P Precautions
In order to ensure safe operation of the Heraeus Multifuge 4KR, the following general safety
regulations must be followed:
• The centrifuge should be operated by trained specialists only.
• The centrifuge is to be used for its intended use only.
• Plug the centrifuge only into sockets which have been properly grounded.
• Do not move the centrifuge while it is running.
• Do not lean on the centrifuge.
• Use only rotors and accessories for this centrifuge which have been approved by Thermo
Fisher Scientific. Exceptions to this rule are commercially available glass or plastic
centrifuge tubes, provided they have been approved for the speed or the RCF value of
the rotor.
• Do not use rotors which show any signs of corrosion and/or cracks.
• Do not touch the mechanical components of the rotor and do not make any changes to
the mechanical components.
• Use only with rotors which have been properly installed. Follow the instructions in
section “Rotor Installation” on page 4-3.
• Use only with rotors which have been loaded properly. Follow the instructions given in
the rotor manual.
• Never overload the rotor. Follow the instructions given in the rotor manual.
• Never open the lid until the rotor has come to a complete stop and this has been
confirmed in the display.
• The lid emergency release may be used in emergencies only to recover the samples from
the centrifuge, e.g. during a power failure (see section “Mechanical Emergency Door
Release” on page 6-2).
• The performance of the gas springs might diminish after some time. Check the gas
springs as described in “Centrifuge Door” on page 4-2.
• Never use the centrifuge if parts of its cover panels are damaged or missing.
• Do not touch the electronic components of the centrifuge or alter any electronic or
mechanical components.
• Please observe the safety instructions.
Thermo Scientific Heraeus Multifuge 4KR v
P Precautions
Remaining risk: Improper use can cause damages, contamination, and injuries
with fatal consequences.
Remaining risk: Improper use can cause damages, contamination, and injuries
with fatal consequences.
Please pay particular attention to the following aspects:
• Location: well-ventilated environment, set-up on a level and rigid surface with adequate
load-bearing capacity.
• Rotor installation: make sure the rotor is locked properly into place before operating the
centrifuge.
• Especially when working with corrosive samples (salt solutions, acids, bases), the
accessory parts and vessel have to be cleaned carefully.
• Always balance the samples.
Centrifuging hazardous substances:
• Do not centrifuge explosive or flammable materials or substances which could react
violently with one another.
• The centrifuge is neither inert nor protected against explosion. Never use the centrifuge
in an explosion-prone environment.
• Do not centrifuge inflammable substances.
• Do not centrifuge toxic or radioactive materials or any pathogenic micro-organisms
without suitable safety precautions.
When centrifuging microbiological samples from the Risk Group II (according to the
Bio-safety Manual" of the World Health Organization (WHO)), aerosol-tight biological
seals have to be used.
For materials in a higher risk group, extra safety measures have to be taken.
• If toxins or pathogenic substances have gotten into the centrifuge or its parts,
appropriate disinfection measures have to be taken (see “Disinfection” on page 5-4).
• Highly corrosive substances which can cause material damage and impair the
mechanical stability of the rotor, should only be centrifuged in corresponding protective
tubes.
WARNING
If a hazardous situation occurs, turn off the power supply to the centrifuge and leave the
area immediately.
vi Heraeus Multifuge 4KR Thermo Scientific
1
Introduction and Description
Contents
• “Characteristics of the Heraeus Multifuge 4KR” on page 1-2
• “Technical Data” on page 1-3
• “Directives, Standards and Guidelines” on page 1-3
• “Functions and Features” on page 1-4
• “Mains Supply” on page 1-5
• “Rotor Selection” on page 1-5
Thermo Scientific Multifuge 4KR 1-1
1 Introduction and Description
Characteristics of the Heraeus Multifuge 4KR
Characteristics of the Heraeus Multifuge 4KR
The Heraeus Multifuge 4KR is a large volume, refrigerated universal centrifuge.
The Heraeus Multifuge 4KR is designed for large volume, high throughput laboratory needs. The
micro test plates and tubes can be centrifuged with the unique double rectangular bucket.
The Heraeus Multifuge 4KR is optimized for the automatic laboratory processes in clinical central labs.
The Diagnostik™ rotor allows the centrifuge commercial sample racks directly.
The Heraeus Multifuge 4KR is also a compact centrifuge for the separation of blood components. A
special wind shield rotor allows to process up to eight quintuple blood bag systems.
The Heraeus Multifuge 4KR is equipped with various safety features:
• The housing and rotor chamber consist of steel plate, the interior of armor steel, while the front
panel is made of high-impact resistant plastic.
• The door is equipped with a view port and a lock.
• The door of the centrifuge can only be opened while the centrifuge is switched on and the rotor
has come to a complete stop. The centrifuge cannot be started until the door has been closed
properly.
• The integrated rotor detection systems ensures that no inadmissible speed settings can be
pre-selected.
• Electronic imbalance detection, SMARTspin.
• Door emergency release: For emergencies only, e.g. during power failures (see “Mechanical
Emergency Door Release” on page 6-2).
1-2 Multifuge 4KR Thermo Scientific
Technical Data
The technical data of the Heraeus Multifuge 4KR is listed in the following table.
Table 1 -1. Technical Data
Feature Value
Environmental Conditions -Use in interior Spaces
Permissible Ambient Temperature +2 °C to +40 °C
Overvoltage Category II
Pollution Degree 2
Heat Dissipation 9200 BTU/h
IP 20
1 Introduction and Description
Technical Data
230 V
-Altitudes of up to 2,000 m above Sea Level
-Max. relative Humidity 80% up to 31 °C; Decreasing linearly up to 50%
relative Humidity at 40 °C.
Run Time Unlimited
Max Speed n
Min Speed n
max
min
Maximum RCF Value at n
max
10000 rpm (Depending on the Rotor)
300 rpm
15317xg
Maximum Kinetic Energy <63.4 kJ
Noise Level at maximum Speed <61 dB(A)
temperature Setting Range -9 °C to +40 °C
Dimensions
Height
Width
Depth
700 mm
680 mm
720 mm
Weight without Rotor 236 kg
Directives, Standards and Guidelines
Table 1 -2. Directives, Standards and Guidelines
Tension /
Frequency
230 V / 60 Hz 2006/95/EC Low Voltage
Directive:
2006/42/EC Machine Directive:
2004/108/EC EMC Directive
Produced and inspected according to the following
Standards and Guidelines
EN 61010-1, 2
EN 61010-2-020, 2
nd
Edition
nd
Edition
EN 61326-1
EN 55011B
EN 61000-6-2
Thermo Scientific Multifuge 4KR 1-3
1 Introduction and Description
Functions and Features
Functions and Features
The following table gives an overview of the important functional and performance characteristics of
the Heraeus Multifuge 4KR.
Table 1-3. Functions and Features
Component / Function Description / Features
Structure / Housing Galvanized Steel Chassis with Armored Plating
Chamber Stainless Steel
Drive Induction Drive without Carbon Brushes
Keys and Display Easy-to-clean Keypad and Display Surface
Controls Microprocessor controlled with Easycontrol II
Internal Memory The most recent Data is saved
Functions RCF-Selection, Temperature Regulation during Standstill, Pre-temp,
Acceleration / Braking Profiles 9 Acceleration and 9 Braking Curves
and PULSE
Rotor Recognition Automatic
Imbalance Detection SMARTspin Electronic, contingent on Rotor and Speed
Door Lock Motor assisted Door Looking
Function Feature
Program Display
Acceleration / Braking Profiles 1 = slow, ... 9 = fast Acceleration / Deceleration Curve
Speed Selection Adjustable from 300 rpm to10,000 rpm in 10 rpm Increments
RCF Selection After actuating the RCF Switch Key, the RCF Value can be entered.
Time Selection Adjustable in Seconds up to 9 min 59sec,
Run Time Display in "quick run"
Mode
Free Program Selection
Operating Memory
1...9
Memory Capacity for Set Values
PULSE-Mode
in the Range of 10 min up to 99 min
in Minutes, "hold"-Mode: Continuous Operation
In seconds Increments
Temperature Selection Adjustable from -9 °C to +40 °C, in 1°C Increments.
End of Run The Speed Display will read End.
Door Opening Automatic Unlocking via Key
(Unlocking in Case of Power Failure: see Chapter "Troubleshooting)
Start Key
Stop Key
1-4 Multifuge 4KR Thermo Scientific
Function Feature
PULSE-Mode Pressing the Key activates maximum Acceleration up to the maximum
Diagnostic Messages Alternating Display rotor /Maximum Speed or RCF (Speed selected exceeds
Mains Supply
The following table contains an overview of the electrical connection data for the Heraeus Multifuge
4KR. This data is to be taken into consideration when selecting the mains connection socket.
Table 1 -4. Electrical connection data
1 Introduction and Description
Mains Supply
permissible Speed of Rotor; upon Key Release Centrifuge stops with maximum
Deceleration Power.
max. Speed of the rotor)
Door has not been lifted off the Lock during opening: Display Lift Lid (Manual
Lifting of Door required)
General Centrifuge Malfunction (Error Messages with ERROR Codes, see
“Troubleshooting by User” on page 6-3)
Cat.
7500 4461 230 V 50 Hz 11.5 A 2.6 kW 16 AT 16 AT
Rotor Selection
The Heraeus Multifuge 4KR is supplied without a rotor.
Various Thermo Scientific rotors are available to choose from.
LH-4000 7500 6475
with round Buckets 1000 7500 6477
Double rectangular Bucket DoubleSpin
LH-4000W 7500 6476
with round Buckets 1000 7500 6477
Double rectangular Bucket DoubleSpin
with double Blood Bag Bucket 7500 6436
Mains
Voltage
Frequency
Rated
Current
TM
2 x 250 7500 6478
TM
2 x 250 7500 6478
Power
Consumption
Equipment
Fuse
Building Fuse
BIOshield 4 x 250 7500 6435
HIGHPlate 5 x 5 Plates 7500 6444
Diagnostik
LAC-250 6 x 250 7500 6483
TM
7500 6480
The technical data of the rotors and the corresponding adapters and reduction sleeves for various
commercially available containers can be found in the corresponding rotor operating manuals.
For more information visit our website at: http://www.thermo.com
Thermo Scientific Multifuge 4KR 1-5
2
Before Use
Contents
• “Before Setting up” on page 2-2
• “Location” on page 2-2
• “Setting up” on page 2-2
• “Transporting the Centrifuge” on page 2-3
• “Mains Connection” on page 2-4
• “Storage” on page 2-4
Thermo Scientific Multifuge 4KR 2-1
2 Before Use
Before Setting up
Before Setting up
1. Check the centrifuge and the packaging for any shipping damage.
Inform the shipping company and Thermo Fisher Scientific immediately if any damage is
discovered.
2. Remove the packaging.
3. Check the order for completeness (see “Scope of Supply” on page iii).
If the order is incomplete, please contact Thermo Fisher Scientific.
Location
The centrifuge should only be operated indoors.
The set-up location must fulfill the following requirements:
• A safety zone of at least 30 cm must be maintained around the centrifuge.
People and hazardous substances must be kept out of the safety zone while centrifuging.
Setting up
• The supporting structure must be stable and free of resonance.
• The supporting structure must be suitable for horizontal setup of the centrifuge.
• The centrifuge should not be exposed to heat and strong sunlight.
WARNING UV rays reduce the stability of plastics.
Do not subject the centrifuge, rotors and plastic accessories to direct sunlight.
• The set-up location must be well-ventilated at all times.
WARNING The centrifuge operated with a high kinetic energy. Do not operate the
centrifuge without a 30 cm (12 inch) safety zone around the centrifuge.
Do not operate the centrifuge on its castors.
CAUTION Do not place anything under the casters to level the centrifuge.
Note The centrifuge is screwed onto the pallet with four screws.
1. Place the pallet with the centrifuge so that you have at leased 2 m room in front of the pallet.
2. Release the rails from the pallet.
2-2 Multifuge 4KR Thermo Scientific
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