1. Product And Company Identification
PRODUCT NAME: POLYCOOL MIX-25
PRODUCT NUMBER: 110-156
MANUFACTURER:
Phoenix Products Company
55 Container Drive
Terryville, CT 06786, USA
BUSINESS PHONE NUMBER: 860-589-7502
EMERGENCY PHONE NUMBER: U.S. PERS 800-633-8253
MSDS DATE OF PREPARATION/REVISION: 9/14/11
2. Composition/Information On Ingredients
Component CAS No. Amount, wt%
Ethylene Glycol 107-21-1 < 50
Poly [oxyethylene (dimenthylimino) ethylene
(dimethyliminio) ethylene dichloride] 131512-74-0 < 0.3
Water 7732-18-5 > 50
(See Section 8 for Exposure Limits)
3. Hazards Identification
Yellow liquid with a characteristic odor.
EMERGENCY OVERVIEW
Eye and upper respiratory irritant. May cause nausea, vomiting, headache, drowsiness, blurred vision, convulsions, coma or
death if ingested or inhaled. Prolonged or repeated skin contact may cause dermatitis or skin sensitization.
4. First Aid Measures
INHALATION: Remove the victim to fresh air. If breathing has stopped administer artificial respiration. If breathing is difficult,
have medical personnel administer oxygen. Get medical attention.
SKIN CONTACT: Remove contaminated clothing. Immediately wash contacted area thoroughly with soap and water. If
irritation persists, get medical attention.
EYE CONTACT: Immediately flush eyes with large amounts of water for 15 minutes. Get medical attention if irritation persists.
INGESTION: Seek immediate medical attention. Immediately call local poison control center or go to an emergency department.
Never give anything by mouth to or induce vomiting in an unconscious or drowsy person.
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NOTES TO PHYSICIAN: The principal toxic effects of ethylene glycol, when swallowed, are kidney damage and metabolic
acidosis. The combination of metabolic acidosis, an osmol gap and oxalate crystals in the urine is evidence of ethylene glycol
poisoning.
Pulmonary edema with hypoxemia has been described in a number of patients following poisoning with ethylene glycol.
Respiratory support with mechanical ventilation may be required.
There may be cranial nerve involvement in the late stages of toxicity from swallowed ethylene glycol. In particular, effects have
been reported involving the seventh, eighth, and ninth cranial nerves, presenting with bilateral facial paralysis, diminished
hearing and dysphagia.
Ethanol is antidotal and its early administration may block the formation of nephrotoxic metabolites of ethylene glycol in the
liver. The objective is to rapidly achieve and maintain a blood ethanol level of approximately 100 mg/dl by giving a loading dose
of ethanol followed by a maintenance dose. Intravenous administration of ethanol is the preferred route. Ethanol blood levels
should be checked frequently. Hemodialysis may be required.
4-Methyl pyrazole (Fomepizole(R)), a potent inhibitor of alcohol dehydrogenase, has been used therapeutically to decrease the
metabolic consequences of ethylene glycol poisoning. Fomepizole is easier to use clinically than ethanol, does not cause CNS
depression or hypoglycemia and requires less monitoring than ethanol. Additional therapeutic modalities which may decrease
the adverse consequences of ethylene glycol metabolism are the administration of both thiamine and pyridoxine. As there are
complicated and serious overdoses, we recommend you consult with the toxicologists at your poison control center.
5. Firefighting Measures
FLASH POINT: Greater than 220 F TOC
AUTOIGNITION TEMPERATURE: Not determined
NFPA CLASSIFICATION: IIIB
FLAMMABILITY LIMITS: LEL: Not determined UEL: Not determined
NFPA CLASSIFICATION: Not Applicable
EXTINGUISHING MEDIA: Use any media appropriate for the surrounding fire.
SPECIAL FIRE FIGHTING PROCEDURES: Do not spray pool fires directly. Firefighters should wear positive pressure selfcontained breathing apparatus and full protective clothing for fires in areas where chemicals are used or stored.
UNUSUAL FIRE HAZARDS: None known.
HAZARDOUS COMBUSTION PRODUCTS: Burning may produce carbon monoxide and carbon dioxide.
6: Accidental Release Measures
Wear appropriate protective clothing and equipment (See Section 8). Collect with absorbent material and place in appropriate,
labeled container for disposal or, if permitted flush spill area with water.
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7. Handling and Storage
DANGER: Harmful or Fatal if Swallowed
Do not drink antifreeze or solution.
Avoid eye and prolonged or repeated skin contact.
Avoid breathing vapors or mists.
Wash exposed skin thoroughly with soap and water after use.
Do not store in opened or unlabeled containers.
Keep container away from open flames and excessive heat.
Do not reuse empty containers unless properly cleaned.
Empty containers retain product residue and may be dangerous. Do not cut, weld, drill, etc. containers, even empty.
Sudden release of hot organic chemical vapors or mists from process equipment operating at elevated temperature and pressure,
or sudden ingress of air into vacuum equipment, may result in ignitions without any obvious ignition sources. Published
"autoignition" or "ignition" temperatures cannot be treated as safe operating temperatures in chemical processes without
analysis of the actual process conditions. Use of this product in elevated temperature applications should be thoroughly
evaluated to assure safe operating conditions.
8. Exposure Controls / Personal Protection
EXPOSURE LIMITS
CHEMICAL EXPOSURE LIMIT
Ethylene Glycol (as aerosol) 100 mg/m3 Ceiling ACGIH TLV
Poly [oxyethylene (dimenthylimino) ethylene
(dimethyliminio) ethylene dichloride] None Established (PEL/TLV)
Water None Established (PEL/TLV)
VENTILATION: Use general ventilation or local exhaust as required to maintain exposures below the occupational exposure
limits.
RESPIRATORY PROTECTION: For operations where the TLV is exceeded a NIOSH approved respirator with organic vapor
cartridges and dust/mist prefilters or supplied air respirator is recommended. Equipment selection depends on contaminant type
and concentration. Select and use in accordance with 29 CFR 1910.134 and good industrial hygiene practice. For firefighting,
use self-contained breathing apparatus.
GLOVES: Chemical resistant gloves such as neoprene or PVC where contact is possible.
EYE PROTECTION: Splash-proof goggles.
OTHER PROTECTIVE EQUIPMENT/CLOTHING: Appropriate protective clothing as needed to minimize skin contact.
9. Physical and Chemical Properties
APPEARANCE AND ODOR: Yellow liquid with a characteristic odor. There is no odor threshold data for this product.
pH: 9.0 SPECIFIC GRAVITY: 1.07
BOILING POINT: 229°F (109°C) VAPOR PRESSURE: < 0.1 mmHg @ 68°F
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MELTING POINT: -34°F (-36°C) VAPOR DENSITY: Not determined
SOLUBILITY IN WATER: Complete EVAPORATION RATE: Not determined
PERCENT VOLATILE: None VISCOSITY: Not determined
COEFFICIENT OF WATER/OIL DISTRIBUTION: Not determined
10. Stability and Reactivity
STABILITY: Stable
CONDITIONS TO AVOID: None
INCOMPATIBILITY: Normally unreactive, however, avoid strong bases at high temperatures, strong acids, strong oxidizing
agents, and materials reactive with hydroxyl compounds.
DECOMPOSITION PRODUCTS: Carbon monoxide, carbon dioxide.
HAZARDOUS POLYMERIZATION: Will not occur.
11. Toxicological Information
POTENTIAL HEALTH EFFECTS:
ACUTE HAZARDS:
INHALATION: May cause irritation of the nose and throat with headache, particularly from mists. High vapor concentrations
caused, for example, by heating the material in an enclosed and poorly ventilated workplace, may produce nausea, vomiting,
headache, dizziness and irregular eye movements.
SKIN CONTACT: No evidence of adverse effects from available information.
EYE CONTACT: Liquid, vapors or mist may cause discomfort in the eye with persistent conjunctivitis, seen as slight excess
redness or conjunctiva. Serious corneal injury is not anticipated.
INGESTION: May cause abdominal discomfort or pain, nausea, vomiting, dizziness, drowsiness, malaise, blurring of vision,
irritability, back pain, decrease in urine output, kidney failure, and central nervous system effects, including irregular eye
movements, convulsions and coma. Cardiac failure and pulmonary edema may develop. Severe kidney damage which may be
fatal may follow the swallowing of ethylene glycol. A few reports have been published describing the development of weakness
of the facial muscles, diminishing hearing, and difficulty with swallowing, during the late stages of severe poisoning.
CHRONIC EFFECTS: Prolonged or repeated inhalation exposure may produce signs of central nervous system involvement,
particularly dizziness and jerking eye movements. Prolonged or repeated skin contact may cause skin sensitization and an
associated dermatitis in some individuals. Ethylene glycol has been found to cause birth defects in laboratory animals. The
significance of this finding to humans has not been determined.
MEDICAL CONDITIONS AGGRAVATED BY EXPOSURE: The available toxicological information and a knowledge of the
physical and chemical properties of the material suggest that overexposure in unlikely to aggravate existing medical conditions.
CARCINOGEN: None of the components of these products is listed as a carcinogen or suspected carcinogen by IARC, NTP or
OSHA.
Acute Toxicity Values:
Ethylene Glycol: LD50 Oral Rat: 4700 mg/kg; LD50 Skin Rabbit: 9530 mg/kg
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SIGNIFICANT LABORATORY DATA WITH POSSIBLE RELEVANCE TO HUMAN HEALTH:
Ethylene glycol has been shown to produce dose-related teratogenic effects in rats and mice when given by gavage or in
drinking water at high concentrations or doses. Also, in a preliminary study to assess the effects of exposure of pregnant rats
and mice to aerosols at concentrations 150, 1,000 and 2,500 mg/m3 for 6 hours a day throughout the period of organogenesis,
teratogenic effects were produced at the highest concentrations, but only in mice. The conditions of these latter experiments
did not allow a conclusion as to whether the developmental toxicity was mediated by inhalation of aerosol, percutaneous
absorption of ethylene glycol from contaminated skin, or swallowing of ethylene glycol as a result of grooming the wetted coat.
In a further study, comparing effects from high aerosol concentration by whole-body or nose-only exposure, it was shown that
nose-only exposure resulted in maternal toxicity (1,000 and 2,500 mg/m3) and developmental toxicity in with minimal evidence of
teratogenicity (2,500 mg/m3). The no-effects concentration (based on maternal toxicity) was 500 mg/m3. In a further study in
mice, no teratogenic effects could be produced when ethylene glycol was applied to the skin of pregnant mice over the period of
organogenesis. The above observations suggest that ethylene glycol is to be regarded as an animal teratogen; there is
currently no available information to suggest that ethylene glycol caused birth defects in humans. Cutaneous application of
ethylene glycol is ineffective in producing developmental toxicity; exposure to high aerosol concentration is only minimally
effective in producing developmental toxicity; the major route for producing developmental toxicity is perorally.
Two chronic feeding studies, using rats and mice, have not produced any evidence that ethylene glycol causes dose-related
increases in tumor incidence or a different pattern of tumors compared with untreated controls. The absence of carcinogenic
potential for ethylene glycol has been supported by numerous invitro genotoxicity studies showing that it does not produce
mutagenic or clastogenic effects.
This products contains less than 0.07% tolytriazole which has demonstrates mutagenic activity in a bacterial test system. A
correlation has been established between mutagenic activity and carcinogenic activity for many chemicals. Tolytriazole has not
been identified as a carcinogen or probable carcinogen by NTP, IARC or OSHA.
12. Ecological Information
Ethylene Glycol: LC50 Goldfish: 5,000 mg/L/24 hr. at 20 C static conditions. Toxicity threshold (cell multiplication inhibition test):
Bacterial (Pseudomonas putida): 10,000 mg/l; Protozoa (Entosiphon sulcatum and Uronema parduczi; Chatton-Lwoff): >10,000
mg/l; Algae (Microcystis aeruginosa): 2,000 mg/l; Green algae (Scenedesmus quandricauda): >10,000 mg/l
13. Disposal Considerations
Dispose of product in accordance with all local, state/provincial and federal regulations.
14. Transport Information
U.S. DOT HAZARD CLASSIFICATION: Not Regulated (unless package contains a reportable quantity)
Note: IF A SHIPMENT OF A REPORTABLE QUANTITY (8,333 LBS/933 GAL.) IN A SINGLE PACKAGE IS INVOLVED, THE
FOLLOWING INFORMATION APPLIES:
PROPER SHIPPING NAME: RQ, Environmentally hazardous substance, liquid, n.o.s. (Ethylene glycol)
UN NUMBER: UN3082
PACKING GROUP: III
LABELS REQUIRED: Class 9
DOT MARINE POLLUTANTS: This product does not contain Marine Pollutants as defined in 49 CFR 171.8.
IMDG CODE SHIPPING CLASSIFICATION: Not Regulated
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CANADIAN TDG CLASSIFICATION: Not Regulated
15. Regulatory Information
EPA SARA 311/312 HAZARD CLASSIFICATION: Acute health, chronic health
EPA SARA 313: This Product Contains the Following Chemicals Subject to Annual Release Reporting Requirements Under
SARA Title III, Section 313 (40 CFR 372):
Ethylene Glycol 107-21-1 40-60%
PROTECTION OF STRATOSPHERIC OZONE: This product is not known to contain or to have been manufactured with ozone
depleting substances as defined in 40 CFR Part 82, Appendix A to Subpart A.
CERCLA SECTION 103: Spills of this product over the RQ (reportable quantity) must be reported to the National Response
Center. The RQ for this product, based on the RQ for Ethylene Glycol (60% maximum) of 5,000 lbs., is 8,333 lbs. Many states
have more stringent release reporting requirements. Report spills required under federal, state and local regulations.
CALIFORNIA PROPOSITION 65: The normal consumer use of this product does not result in exposures to chemicals known to
the State of California to cause Cancer and/or Reproductive Harm above the significant risk level for carcinogens or the
maximum allowable dose levels for reproductive toxins. Therefore, no warnings are required for consumer packages. Industrial
or other occupational use of this product at higher frequency and using larger quantities of this product may result in exposures
exceeding these levels and are labeled accordingly.
EPA TSCA INVENTORY: All of the components of this material are listed on the Toxic Substances Control Act (TSCA)
Chemical Substances Inventory.
CANADIAN ENVIRONMENTAL PROTECTION ACT: All of the ingredients are listed on the Canadian Domestic Substances
List.
CANADIAN WHMIS CLASSIFICATION: Class D - Division 2 - Subdivision A - (A very toxic material causing other toxic
effects)
CANADIAN WHMIS HAZARD SYMBOLS:
This MSDS has been prepared according to the criteria of the Controlled Products Regulation (CPR) and the MSDS contains all
of the information required by the CPR.
EUROPEAN INVENTORY OF EXISTING COMMERCIAL CHEMICAL SUBSTANCES (EINECS): All of the ingredients are listed
on the EINECS inventory.
AUSTRALIA: All of the ingredients of this product are listed on the Australian Inventory of Chemical Substances.
JAPAN: All of the ingredients of this product are listed on the Japanese Existing and New Chemical Substances (METI) List.
16. Other Information
NFPA RATING (NFPA 704) - FIRE: 0 HEALTH: 1 REACTIVITY: 0
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