PolyScience Polycool EG -25 Data sheet
PRODUCT NAME: polycool EG -25
PART NUMBER: 060340
REVISION DATE: 01/14/2010
1. IDENTIFICATION OF THE SUBSTANCE AND COMPANY
Chemical Name: Ethylene glycol
CAS no. 107-21-1
Product Description: colorless liquid with sweet odor.
MATERIAL SAFETY DATA SHEET
SUPERSEDES: 11/30/2006
Supplier:
Univar USA Inc.
17425 NE Union Hill Rd
Redmond, WA 98052
Bottler:
Accumetric Inc
411 E Dixie
Elizabethtown, KY 42701
Telephone: (425)889-3400
FOR EMERGENCY ASSISTANCE INVOLVING CHEMICALS, CALL - CHEMTREC (800) 424-9300
2. HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Color: Colorless
Physical State: Liquid
Odor: Sweet
Hazards of Product: WARNING! Harmful or fatal if swallowed. May cause eye irritation. Isolate area.
OSHA Hazard Communication Standard
is product is a “Hazardous Chemical” as de ned by the OSHA Hazard Communication Standard, 29 CFR 1910.1200.
POTENTIAL HEALTH EFFECTS:
Eye Contact:
May cause slight eye irritation. Corneal injury is unlikely. Vapor or mist may cause eye irritation.
Distributor:
PolyScience
6600 W Touhy Ave
Niles, IL 60714
Telephone: (847)647-0611
Skin Contact:
Skin Absorption:
Inhalation:
Ingestion:
Brief contact is essentially nonirritating to skin. Prolonged contact may cause slight skin irritation with local redness. Repeated contact
may cause skin irrittaion with local redness.
Prolonged skin contact is unlikely to result in absorption of harmful amounts. Repeated skin exposure to large quantities may result in
absorption of harmful amounts. Massive contact with damaged skin or of material su ciently hot to burn skin may result in absorption
of potentially lethal amounts.
At room temperature, exposure to vapor is minimal due to low volatility. With good ventilation, single exposure is not expected to
cause adverse e ects. If material is heated or areas are poorly ventilated, vapor/mist may accumulate and cause respiratory irritation
and symptom such as headache and nausea.
Oral toxicity is expected to be moderate in humans due to ethylene glycol even though tests with animals show a lower degree of
toxicity. Small amounts swallowed incidentally as a result of normal handling operations are not likely to cause injury; however,
swallowing larger amounts may cause serious injury, even death. May cause nausea and vomiting. May cause abdominal discomfort
or diarrhea. Excessive exposure may cause central nervous system e ects, cariodpulmonary e ects (metabolic acidosis), and kidney
failure.
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MSDS part number: 110-157
POTENTIAL HEALTH EFFECTS continued.
EFFECTS OF REPEATED EXPOSURE:
Repeated excessive exposure may cause irritation of the upper respiratory tract. In humans, e ects have been
reported on the following organs: Central nervous system. Observations in humans include: Nystagmus
(involuntary eye movement). In animals, e ects have been reported on the following organs: Kidney, Liver.
BIRTH DEFECTS/DEVELOPMENTAL EFFECTS:
REPRODUCTIVE EFFECTS:
Based on animal studies, ingestion of very large amounts of ethylene glycol appears to be the major and possibly
only route of exposure to produce birth defects. Exposure by inhalation or skin contact, the primary routes of
occupational exposure, had minimal e ects on the fetus, in animal studies.
Injestion of large amounts of ethylene glycol has been shown to interfere with reproduction in animals.
NFPA Ratings (0-4): Health: 1
Fire: 1
Reactivity: 0
3. COMPOSITION/INGREDIENTS INFORMATION
COMPONENT CAS NO. WEIGHT %
Ethylene glycol 107-21-1 >99.0%
4. FIRST-AID MEASURES
EYE CONTACT:
SKIN CONTACT:
INHALATION:
INGESTION:
Flush eyes thoroughly with water for several minutes. Remove contact lenses a er the initial 1-2 minutes and continue ushing for
several additional minutes. If e ects occur, consult a physician, preferably an ophthalmologist.
Wash skin with plenty of water.
Move person to fresh air. If not breathing, give arti cial respiration; if by mouth to mouth, use rescuer protection (pocket masks,
etc). If breathing is di cult, oxygen should be administered by quali ed personnel. Call a physician or transport to a medical facility
immediately.
Do not induce vomiting. Seek medical attention immediately. If person is fully conscious, give 1 cup or 8 ounces (240ml) of water. If
medical advice is delayed and if an adult has swallowed several ounces of chemical, then give 3-4 ounces (1/3-1/2 Cup) (90-120ml) of
hard liquor such as 80 proof whiskey. For children, give proportionally less liquor at a dose of 0.3 ounce (1 1/2 tsp.) (8ml) liquor for
each 10 pounds of body weight, or 2ml per kg body weight (e.g., 1.2 ounce (2 1/3 tbsp.) for a 40 pound child or 36ml for an 18kg child).
NOTE TO PHYSICIAN:
If several ounces (60-100ml) of ethylene glycol have been ingested, early administration of ethanol may counter the toxic e ect
(metabolic acidosis, renal damage). Consider hemodialysis or peritoneal dialysis & thiamine 100mg plus pyridoxine 50mg
intravenously every 6 hours. If ethanol is used, a therapeutically e ective blood concentration in the range of 100-150mg/dl may be
achieved by a rapid loading dose followed by a continuous intravenous infusion. Consult standard literature for details of treatment.
4-Methyl pyrazole (Antizol*) is an e ective blocker of alcohol dehydrogenase and should be used in the treatment of ethylene glycol
(EG), di- or triethylene glycol (DEG, TEG), ethylene glycol butyl ether (EGBE), or methanol intoxication if available. Fonepizole
protocol (Brent, J. et al., New England Journal of Medicine, Feb. 8, 2001, 344:6, p. 434-9); loading dose 15mg/kg intravenously, followed
by bolus dose of 10mg/kg every 12 hours; a er 48 hours, increase bolus dose to 15mg/kg every 12 hours. Continue fonepizole until
serum methanol, EG, DEG, TEG, or EGBA are undetectable. e signs and symptoms of poisoning include anion gap metabolic
acidosis, CNS depression, renal tubular injury, and possible late stage cranial nerve involvement. Respiratory symptoms, including
pulmonary edema, may be delayed. Person receiving signi cant exposure should be observed 24-48 hours for signs of respiratory
distress. Maintain adequate ventilation and oxygenation of the patient. In severe poisoning, respiratory support with mechanical
ventilation and positive end expiratory pressure may be required. If lavage is performed, suggest endotracheal and/or esophageal
control. Danger from lung aspiration must be weighed against toxicity when considering emptying the stomach. If burn is present,
treat as any thermal burn, a er decontamination. Treatment of exposure should be directed at the control of symptoms and the clinical
condition of the patient.
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5. FIRE-FIGHTING MEASURES
SUITABLE EXTINGUISHING MEDIA:
FIRE FIGHTING PROCEDURE:
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS:
UNUSUAL FIRE AND EXPLOSION HAZARDS:
HAZARDOUS COMBUSTION PRODUCTS:
Water fog or ne spray. Dry chemical re extinguishers. Carbon dioxide re extinguishers. Foam.
Do not use direct water stream. May spread re. Alcohol (ATC type) are preferred. General purpose
synthetic foams (including AFFF) or protein foams may function, but will be less e ective.
Keep people away. Isolate re and deny unnecessary entry. Use water spray to cool re exposed
containers and re a ected zone until re is out and danger of reignition has passed. Fight re from
protected location or safe distance. Consider the use of unmanned hose holders or monitor nozzles.
Immediately withdraw all personnel from the area in case of rising sound from venting safety device
or discoloration of the container. Burning liquids may be extinguished by dilution with water. Do
not use direct water stream. May spread re. Move container from re area if this is possible without
hazard. Burning liquids may be moved by ushing with water to protect personnel and minimize
property damage.
Wear positive-pressure self-contained breathing apparatus (SCBA) and protective re ghting
clothing (includes re ghting helmet, coat, trousers, boots, and gloves). If protective equipment is
not available or not used, ght re from a protected location or safe distance.
Container may rupture from gas generation in a re situation. Violent steam generation or eruption
may occur upon application of direct water stream to hot liquids.
During a re, smoke may contain the original material in addition to combustion products of varying
composition which may be toxic and/or irritating. Combustion products may include and are not
limited to: Carbon monoxide, Carbon dioxide.
6. ACCIDENTAL RELEASE MEASURES
Steps to be Taken if Material is Released or Spilled: Contain spilled material if possible. Collect in suitable and properly labeled container.
Small spills: Absorb with materials such as: Cat litter, Sand, Sawdust, Vermiculite, Zorb-all*, Hazorb*.
Large spills: Dike area to contain spill. Pump into suitable and properly labeled containers. See Section 13, Disposal Considerations, for additional information.
Ignition Sources Removal: Keep away from sources of ignition.
Dust Control: Not applicable.
Personal Precautions: Isolate area. Keep unnecessary and unprotected personnel from entering the area. Use appropriate safety equipment. For additional information,
refer to Section 8, Exposure Controls/Personal Protection. Refer to Section 7, Storage and Handling, for additional precautionary measures.
Environmental Precautions: Prevent from entering into soil, ditches, sewers, waterways and/or groundwater. See Section 12, Ecological Information.
7. STORAGE AND HANDLING
HANDLING
GENERAL HANDLING:
STORAGE
Do not swallow. Avoid contact with eyes. Wash thoroughly a er handling. Spills of these organic materials on hot brous
insulations may lead to lowering of the Autoignition temperatures possibly resulting in spontaneous combustion. See
Section 8, Exposure Controls/Personal Protection.
Do not store near food, foodstu s, drugs or potable water supplies. Additional storage and handling information on this
product may be obtained by calling Univar’s sales or customer service contact. Ask for a product brochure.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Exposure Limits
Component List Type Value
Ethylene Glycol ACGIH Ceiling 100mg/m
Aerosol
Personal Protection
EYE/FACE PROTECTION:
SKIN PROTECTION:
HAND PROTECTION:
Use safety glasses. If exposure causes eye discomfort, use a full-face respirator.
Use protective clothing chemically resistant to this material. Selection of speci c items such as face shield, boots, apron, or full body
suit will depend on the task. Remove contaminated clothing immediately, wash skin area with soap and water, and launder clothing
before reuse or dispose of properly. When handling hot material, protect skin from thermal burns as well as from skin absorption.
If hands are cut or scratched, use gloves chemically resistant to this material even for brief exposures. Use gloves with insulation for
thermal protection, when needed. Examples of preferred glove barrier materials include: Butyl rubber, Natural rubber ( “latex”),
Neoprene, Nitrile/butadiene rubber (“nitrile” or “NBR”), Polyethylene, Ethyl vinyl alcohol laminate (“EVAL”), Polyvinyl alcohol
(“PVA”), Polyvinyl chloride (“PVC” or “vinyl”). NOTICE: e selection of a speci c glove for a particular application and duration
of use in a workplace should also take in to account all relevant workplace factors such as, but not limited to: Other chemicals which
may be handled, physical requirements (cut/puncture protection, dexterity, thermal protection), potential body reactions to glove
materials, as well as the instructions/speci cations provided by the glove supplier.
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