PRODUCT NAME: polycool EG -25
PART NUMBER: 060340
REVISION DATE: 01/14/2010
1. IDENTIFICATION OF THE SUBSTANCE AND COMPANY
Chemical Name: Ethylene glycol
CAS no. 107-21-1
Product Description: colorless liquid with sweet odor.
MATERIAL SAFETY DATA SHEET
SUPERSEDES: 11/30/2006
Supplier:
Univar USA Inc.
17425 NE Union Hill Rd
Redmond, WA 98052
Bottler:
Accumetric Inc
411 E Dixie
Elizabethtown, KY 42701
Telephone: (425)889-3400
FOR EMERGENCY ASSISTANCE INVOLVING CHEMICALS, CALL - CHEMTREC (800) 424-9300
2. HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Color: Colorless
Physical State: Liquid
Odor: Sweet
Hazards of Product: WARNING! Harmful or fatal if swallowed. May cause eye irritation. Isolate area.
OSHA Hazard Communication Standard
is product is a “Hazardous Chemical” as de ned by the OSHA Hazard Communication Standard, 29 CFR 1910.1200.
POTENTIAL HEALTH EFFECTS:
Eye Contact:
May cause slight eye irritation. Corneal injury is unlikely. Vapor or mist may cause eye irritation.
Distributor:
PolyScience
6600 W Touhy Ave
Niles, IL 60714
Telephone: (847)647-0611
Skin Contact:
Skin Absorption:
Inhalation:
Ingestion:
Brief contact is essentially nonirritating to skin. Prolonged contact may cause slight skin irritation with local redness. Repeated contact
may cause skin irrittaion with local redness.
Prolonged skin contact is unlikely to result in absorption of harmful amounts. Repeated skin exposure to large quantities may result in
absorption of harmful amounts. Massive contact with damaged skin or of material su ciently hot to burn skin may result in absorption
of potentially lethal amounts.
At room temperature, exposure to vapor is minimal due to low volatility. With good ventilation, single exposure is not expected to
cause adverse e ects. If material is heated or areas are poorly ventilated, vapor/mist may accumulate and cause respiratory irritation
and symptom such as headache and nausea.
Oral toxicity is expected to be moderate in humans due to ethylene glycol even though tests with animals show a lower degree of
toxicity. Small amounts swallowed incidentally as a result of normal handling operations are not likely to cause injury; however,
swallowing larger amounts may cause serious injury, even death. May cause nausea and vomiting. May cause abdominal discomfort
or diarrhea. Excessive exposure may cause central nervous system e ects, cariodpulmonary e ects (metabolic acidosis), and kidney
failure.
Page 1
MSDS part number: 110-157
POTENTIAL HEALTH EFFECTS continued.
EFFECTS OF REPEATED EXPOSURE:
Repeated excessive exposure may cause irritation of the upper respiratory tract. In humans, e ects have been
reported on the following organs: Central nervous system. Observations in humans include: Nystagmus
(involuntary eye movement). In animals, e ects have been reported on the following organs: Kidney, Liver.
BIRTH DEFECTS/DEVELOPMENTAL EFFECTS:
REPRODUCTIVE EFFECTS:
Based on animal studies, ingestion of very large amounts of ethylene glycol appears to be the major and possibly
only route of exposure to produce birth defects. Exposure by inhalation or skin contact, the primary routes of
occupational exposure, had minimal e ects on the fetus, in animal studies.
Injestion of large amounts of ethylene glycol has been shown to interfere with reproduction in animals.
NFPA Ratings (0-4): Health: 1
Fire: 1
Reactivity: 0
3. COMPOSITION/INGREDIENTS INFORMATION
COMPONENT CAS NO. WEIGHT %
Ethylene glycol 107-21-1 >99.0%
4. FIRST-AID MEASURES
EYE CONTACT:
SKIN CONTACT:
INHALATION:
INGESTION:
Flush eyes thoroughly with water for several minutes. Remove contact lenses a er the initial 1-2 minutes and continue ushing for
several additional minutes. If e ects occur, consult a physician, preferably an ophthalmologist.
Wash skin with plenty of water.
Move person to fresh air. If not breathing, give arti cial respiration; if by mouth to mouth, use rescuer protection (pocket masks,
etc). If breathing is di cult, oxygen should be administered by quali ed personnel. Call a physician or transport to a medical facility
immediately.
Do not induce vomiting. Seek medical attention immediately. If person is fully conscious, give 1 cup or 8 ounces (240ml) of water. If
medical advice is delayed and if an adult has swallowed several ounces of chemical, then give 3-4 ounces (1/3-1/2 Cup) (90-120ml) of
hard liquor such as 80 proof whiskey. For children, give proportionally less liquor at a dose of 0.3 ounce (1 1/2 tsp.) (8ml) liquor for
each 10 pounds of body weight, or 2ml per kg body weight (e.g., 1.2 ounce (2 1/3 tbsp.) for a 40 pound child or 36ml for an 18kg child).
NOTE TO PHYSICIAN:
If several ounces (60-100ml) of ethylene glycol have been ingested, early administration of ethanol may counter the toxic e ect
(metabolic acidosis, renal damage). Consider hemodialysis or peritoneal dialysis & thiamine 100mg plus pyridoxine 50mg
intravenously every 6 hours. If ethanol is used, a therapeutically e ective blood concentration in the range of 100-150mg/dl may be
achieved by a rapid loading dose followed by a continuous intravenous infusion. Consult standard literature for details of treatment.
4-Methyl pyrazole (Antizol*) is an e ective blocker of alcohol dehydrogenase and should be used in the treatment of ethylene glycol
(EG), di- or triethylene glycol (DEG, TEG), ethylene glycol butyl ether (EGBE), or methanol intoxication if available. Fonepizole
protocol (Brent, J. et al., New England Journal of Medicine, Feb. 8, 2001, 344:6, p. 434-9); loading dose 15mg/kg intravenously, followed
by bolus dose of 10mg/kg every 12 hours; a er 48 hours, increase bolus dose to 15mg/kg every 12 hours. Continue fonepizole until
serum methanol, EG, DEG, TEG, or EGBA are undetectable. e signs and symptoms of poisoning include anion gap metabolic
acidosis, CNS depression, renal tubular injury, and possible late stage cranial nerve involvement. Respiratory symptoms, including
pulmonary edema, may be delayed. Person receiving signi cant exposure should be observed 24-48 hours for signs of respiratory
distress. Maintain adequate ventilation and oxygenation of the patient. In severe poisoning, respiratory support with mechanical
ventilation and positive end expiratory pressure may be required. If lavage is performed, suggest endotracheal and/or esophageal
control. Danger from lung aspiration must be weighed against toxicity when considering emptying the stomach. If burn is present,
treat as any thermal burn, a er decontamination. Treatment of exposure should be directed at the control of symptoms and the clinical
condition of the patient.
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5. FIRE-FIGHTING MEASURES
SUITABLE EXTINGUISHING MEDIA:
FIRE FIGHTING PROCEDURE:
SPECIAL PROTECTIVE EQUIPMENT FOR FIREFIGHTERS:
UNUSUAL FIRE AND EXPLOSION HAZARDS:
HAZARDOUS COMBUSTION PRODUCTS:
Water fog or ne spray. Dry chemical re extinguishers. Carbon dioxide re extinguishers. Foam.
Do not use direct water stream. May spread re. Alcohol (ATC type) are preferred. General purpose
synthetic foams (including AFFF) or protein foams may function, but will be less e ective.
Keep people away. Isolate re and deny unnecessary entry. Use water spray to cool re exposed
containers and re a ected zone until re is out and danger of reignition has passed. Fight re from
protected location or safe distance. Consider the use of unmanned hose holders or monitor nozzles.
Immediately withdraw all personnel from the area in case of rising sound from venting safety device
or discoloration of the container. Burning liquids may be extinguished by dilution with water. Do
not use direct water stream. May spread re. Move container from re area if this is possible without
hazard. Burning liquids may be moved by ushing with water to protect personnel and minimize
property damage.
Wear positive-pressure self-contained breathing apparatus (SCBA) and protective re ghting
clothing (includes re ghting helmet, coat, trousers, boots, and gloves). If protective equipment is
not available or not used, ght re from a protected location or safe distance.
Container may rupture from gas generation in a re situation. Violent steam generation or eruption
may occur upon application of direct water stream to hot liquids.
During a re, smoke may contain the original material in addition to combustion products of varying
composition which may be toxic and/or irritating. Combustion products may include and are not
limited to: Carbon monoxide, Carbon dioxide.
6. ACCIDENTAL RELEASE MEASURES
Steps to be Taken if Material is Released or Spilled: Contain spilled material if possible. Collect in suitable and properly labeled container.
Small spills: Absorb with materials such as: Cat litter, Sand, Sawdust, Vermiculite, Zorb-all*, Hazorb*.
Large spills: Dike area to contain spill. Pump into suitable and properly labeled containers. See Section 13, Disposal Considerations, for additional information.
Ignition Sources Removal: Keep away from sources of ignition.
Dust Control: Not applicable.
Personal Precautions: Isolate area. Keep unnecessary and unprotected personnel from entering the area. Use appropriate safety equipment. For additional information,
refer to Section 8, Exposure Controls/Personal Protection. Refer to Section 7, Storage and Handling, for additional precautionary measures.
Environmental Precautions: Prevent from entering into soil, ditches, sewers, waterways and/or groundwater. See Section 12, Ecological Information.
7. STORAGE AND HANDLING
HANDLING
GENERAL HANDLING:
STORAGE
Do not swallow. Avoid contact with eyes. Wash thoroughly a er handling. Spills of these organic materials on hot brous
insulations may lead to lowering of the Autoignition temperatures possibly resulting in spontaneous combustion. See
Section 8, Exposure Controls/Personal Protection.
Do not store near food, foodstu s, drugs or potable water supplies. Additional storage and handling information on this
product may be obtained by calling Univar’s sales or customer service contact. Ask for a product brochure.
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Exposure Limits
Component List Type Value
Ethylene Glycol ACGIH Ceiling 100mg/m
Aerosol
Personal Protection
EYE/FACE PROTECTION:
SKIN PROTECTION:
HAND PROTECTION:
Use safety glasses. If exposure causes eye discomfort, use a full-face respirator.
Use protective clothing chemically resistant to this material. Selection of speci c items such as face shield, boots, apron, or full body
suit will depend on the task. Remove contaminated clothing immediately, wash skin area with soap and water, and launder clothing
before reuse or dispose of properly. When handling hot material, protect skin from thermal burns as well as from skin absorption.
If hands are cut or scratched, use gloves chemically resistant to this material even for brief exposures. Use gloves with insulation for
thermal protection, when needed. Examples of preferred glove barrier materials include: Butyl rubber, Natural rubber ( “latex”),
Neoprene, Nitrile/butadiene rubber (“nitrile” or “NBR”), Polyethylene, Ethyl vinyl alcohol laminate (“EVAL”), Polyvinyl alcohol
(“PVA”), Polyvinyl chloride (“PVC” or “vinyl”). NOTICE: e selection of a speci c glove for a particular application and duration
of use in a workplace should also take in to account all relevant workplace factors such as, but not limited to: Other chemicals which
may be handled, physical requirements (cut/puncture protection, dexterity, thermal protection), potential body reactions to glove
materials, as well as the instructions/speci cations provided by the glove supplier.
3
Page 3
PERSONAL PROTECTION continued.
RESPIRATORY PROTECTION:
Atmospheric levels should be maintained below the exposure guideline. When respiratory protection is required for certain
operations, use an approved air-purifying respirator. e following should be e ective types of air-purifying respirators: Organic
vapor cartridge with a particulate pre- lter.
INGESTION:
ENGINEERING CONTROLS
VENTILATION:
Use good personal hygiene. Do not consume or store food in the work area. Wash hands before smoking or eating.
Provide general and/or local exhaust ventilation to control airborne levels below the exposure guidelines.
9. PHYSICAL AND CHEMICAL PROPERTIES
Physical State: Liquid
Color: Colorless
Odor: Sweet
Flash Point - Closed Cup: 116°C (241°F) ASTM D56
Flammable Limits in Air: Lower: 3.2% (V) Literature
Upper: 15.2% (V) Literature
Autoignition Temperature: 427°C (801°F) Literature
Vapor Pressure: 0.05mmHg @ 20°C Literature
Boiling Point (760mmHg): >197°C (>387°F) Literature
Vapor Density (air = 1): 2.1 Literature
Speci c Gravity (H2O = 1): 1.115 20 c/20 Literature
Freezing Point: -13°C (9°F) Literature
Melting Point: Not applicable
Solubility in Water (by weight): 100% Literature
pH 9 Literature
Molecular Weight: 62g/mol Literature
Octanol/Water Partition -1.36 Measure Coe cient
Evaporation Rate (Butyl Acetate =1 ): 0.01 Literature
10. STABILITY AND REACTIVITY
Stability/Instability
Stable under recommended storage conditions. See Storage and Handling, Section 7
Incompatible Materials: Avoid contact with: Strong acids. Strong bases. Strong oxidizers.
Conditions to Avoid: Exposure to elevated temperatures can cause product to decompose. Generation of gas during decomposition can cause pressure in closed systems.
ermal Decomposition.
Decomposition products depend upon temperature, air supply and the presence of other materials. Decomposition products can include and are not limited to:
Aldehydes, Ketones, Organic acids.
Hazardous Polymerization
Will not occur.
11. TOXICOLOGICAL INFORMATION
Acute Toxicity
Ingestion
For ethylene glycol: Lethal Dose, Human, adult 3 ounces
LD50, Rat: 6,000-13,000mg/kg
Skin Absorption: LD50, Rabbit: >22,270mg/kg
Inhalation: LC50, 7 h, Aerosol, Rat: >3.95mg/L
Repeated Dose Toxicity: Repeated excessive exposure may cause irritation of the upper respiratory tract. In humans, e ects have been reported on the following organs:
Central nervous sytem. Observations in humans include: Nystagmus (involuntary eye movement). In animals, e ects have been reported on the following organs:
Kidney, Liver.
Chronic Toxicity and Carcinogenicity: Ethylene glycol did not cause cancer in long-term animal studies.
Developmental Toxicity: Based on animal studies, ingestion of very large amounts of ethylene glycol appears to be the major and possibly only route of exposure to
produce birth defects. Exposures by inhalation or skin contact, the primary routes of occupational exposure, had minimal e ects on the fetus in animal studies.
Reproductive Toxicity: Ingestion of large amounts of ethylene glycol has been shown to interfere with reproduction in animals.
Genetic Toxicology: In vitro genetic toxicity studies were negative. Animal genetic toxicity studies were negative.
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12. ECOLOGICAL INFORMATION
CHEMICAL FATE
Movement & Partitioning
Bioconcentration potential is low (BCF <100 or Log Pow <3). Potential for mobility in soil is very high (Koc between 1 and 50). Given its very low Henry’s constant,
volatilization from natural bodies of water or moist soil is not expected to be an important fate process.
Henry’s Law Constant (H): 8.05E-09 atm*m
Partition coe cient, n-octanol/water (log Pow): -1.36 Measured
Partition coe cient, soil organic carbon/water (Koc): 1 Estimated
Distribution in Environment: Mackay Level 1 Fugacity Model:
Air Water Biota Soil Sediment
2.1% 98% <0.01% <0.01% <0.01%
Persistence and Degradability
Material is readily biodegradable. Passes OECD test(s) for ready biodegradability. Material is ultimately biodegradable (reaches >70% mineralization in OECD test(s) for
inherent biodegradability). Indirect Photodegradation with OH Radicals.
Rate Constant Atmospheric Half-Life Method
8.32E-12 cm3/s 15 h Estimated
OEDC Biodegradation Test
Biodegradation Exposure Time Method
>94% 28 d OECD 301 F Test
eoretical Oxygen Demand: 1.29mg/mg
3
/mole; 25 C Estimated
ECOTOXICITY
Material is practically non-toxic to aquatic organisms on an acute basis (LC50/EC50 >100mg/L in the most sensitive species tested).
Fish Acute & Prolonged Toxicity
LC50, rainbow trout (Oncorhynchus mykiss), static, 96 h: 18,000 – 46,000 mg/L
Aquatic Invertebrate Acute Toxicity
LC50, water ea Daphnia magna, static, 48 h: 46,300 – 51,000 mg/L
Aquatic Plant Toxicity
EC50, green alga Selenastrum capricornutum, biomass growth inhibition, 96 h: 9,500 – 13,000 mg/L
Toxicity to Micro-organisms
EC50, OECD 209 Test; activated sludge, respiration inhibition, 30 min: 225 mg/L
13. DISPOSAL CONSIDERATIONS
DO NOT DUMP INTO ANY SEWERS, ON THE GROUND, OR INTO ANY BODY OF WATER. All disposal practices must be in compliance with all Federal, State/
Provincial and local laws and regulations. Regulations may vary in di erent locations. Water characterizations and compliance with applicable laws are the responsibility
solely of the waste generator. WE HAVE NO CONTROL OVER THE MANAGEMENT PRACTICES OR MANUFACTURING PROCESSES OF PARTIES HANDLING
OR USING THIS MATERIAL. THE INFORMATION PRESENTED HERE PERTAINS ONLY TO THE PRODUCT AS SHIPPED IN ITS INTENDED CONDITION
AS DESCRIBED IN MSDS SECTION: 3. Composition/Ingredients Information. FOR UNUSED & UNCONTAMINATED PRODUCT, the preferred options include
sending to a licensed, permitted: Recycler, Reclaimer, Incinerator or other thermal destruction device. As a service to our customers, Univar or the supplier can provide
names of information resources to help identify water management companies and other facilities which recycle, reprocess or manage chemicals or plastics, and that
manage used drums. Please contact Univar’s or the supplier’s Customer Information Group (telephone number in Section 1 of this document) for further details.
14. TRANSPORTATION INFORMATION
DOT Non-Bulk
NOT REGULATED
DOT Bulk
Proper Shipping Name: OTHER REGULATED SUBSTANCES, LIQUID, NOS
Technical Name: CONTAINS ETHYLENE GLYCOL
Hazard Class: 9 ID Number: NA3082 Packing Group: PG III
Page 5
TRANSPORTATION INFORMATION continued.
IMDG
Proper Shipping Name: OTHER REGULATED SUBSTANCES, LIQUID, NOS
Technical Name: CONTAINS ETHYLENE GLYCOL
Hazard Class: 9 ID Number: NA3082 Packing Group: PG III
Marine Pollutant: No.
THIS SHIPMENT IS MARKED, LABELED AND/OR PLACARDED AND DESCRIBED IN ACCORDANCE WITH US DOT REGULATIONS AND IS NOT
REGULATED BY IMDG.
ICAO/IATA
NOT REGULATED
Additional Information
Reportable quantity: 5,05 lb – ETHYLENE GLYCOL
is information is not intended to convey all speci c regulatory or operational requirements/information relating to this product. Additional transportation system
information can be obtained through an authorized sales or customer service representative. It is the responsibility of the transporting organization to follow all
applicable laws, regulations and rules relating to the transportation of the material.
15. REGULATORY INFORMATION
OSHA Hazard Communication Standard
is product is a Hazardous Chemical as de ned by the OSHA Hazard communication Standard, 29 CFR 1910.1200 Superfund Amendments and Reauthorization Act of
1986 Title III (Emergency Planning and Community Right-to-Know Act of 1986) Sections 311 and 312
Immediate (Acute) Health Hazard Yes
Delayed (Chronic) Health Hazard Yes
Fire Hazard No
Reactive Hazard No
Sudden Release of Pressure Hazard No
Superfund Amendments and Reauthorization Act of 1896 Title III (Emergency Planning and Community Righ-to-Know Act of 1986) Section 313
is product contains the following substances which are subject to the reporting requirements of Section 313 of Title III of the Superfund Amendmends and
Reauthorization Act of 1986 and which are listed 40 CFR 372.
Component CAS # Amount
Ethylene Glycol 107-21-1 >99.0%
Pennsylvania (Worker and Community Right-to-Know Act): Pennsylvania Hazardous Substances List and/or Pennsylvania Environmental Hazardous Substance List:
e following product components are cited in the Pennsylvania Hazardous Substance List and/or the Pennsylvania Environmental Substance List, and are present at
levels which require reporting.
Component CAS # Amount
Ethylene Glycol 107-21-1 >99.0%
Pennsylvania (Worker and Community Right-to-Know Act): Pennsylvania Hazardous Substances List and/or Pennsylvania Environmental Hazardous Substance List:
To the best of our knowledge, this product does not contain chemical levels which require reporting under this statute.
California Proposition 65 (Safe Drinking Water and Toxic Enforcement Act of 1986) WARNING: is product contains a chemical(s) known to the State of California to
cause cancer.
Component CAS # Amount
Acetaldehyde 75-07-0 <= 8.0 PPM
1,4-Dioxane 123-91-1 <= 0.25 PPM
U.S. Toxic Substances Control Act
All components of this product are on the TSCA Inventory or are exempt from TSCA Inventory requirements under 40 CFR 720.30
European Inventory of Existing Commercial Chemical Substances (EINECS)
is product is on the EINECS inventory.
CEPA –Domestic Substances List (DSL)
All substances contained in this product are listed on the Canadian Domestic Substances List (DSL) or are not required to be listed.
Page 6
16. OTHER INFORMATION
Recommended Uses and Restrictions
For industrial use. It is recommended that you use this product in a manner consistent with the recommended use.
Legend
N/A Not available
W/W Weight/Weight
OEL Occupational Exposure Limit
STEL Short Term Exposure Limit
TWA Time Weighted Average
ACGIH American Conference of Governmental Industrial Hygienists, Inc.
DOW IHG Dow Industrial Hygiene Guidelines
WEEL Workplace Environmental Exposure Level
HAZ DES Hazard Designation
Action Level A value set by OSHA that is lower than the PEL which will trigger the need for activities such as exposure monitoring and medical
surveillance if exceeded.
CONTACT MSDS COORDINATOR (UNIVAR USA INC) DURING BUSINESS HOURS, PACIFIC TIME (425) 889-3400
MSDS prepared by UNIVAR USA.
Product manufactured by UNIVAR, bottled and packed for distribution by Accumetric, and distributed by PolyScience.
******************************* UNIVAR USA INC (“UNIVAR”) and POLYSCIENCE EXPRESSLY DISCLAIM
ALL EXPRESS OR IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE, WITH RESPECT TO THE PRODUCT OR
INFORMATION PROVIDED HEREIN, AND SHALL UNDER NO CIRCUMSTANCES BE LIABLE FOR INCIDENTAL OR CONSEQUENTIAL DAMAGES.
DO NOT USE INGREDIENT INFORMATION AND/OR PERCENTAGES IN THIS MSDS AS A PRODUCT SPECIFICATION. FOR PRODUCT SPECIFICATION
INFORMTAION REFER TO A PRODUCT SPECIFICATION SHEET AND/OR A CERTIFICATE OF ANALYSIS. THESE CAN BE OBTAINED FROM YOUR LOCAL
UNIVAR SALES OFFICE.
ALL INFORMATION APPEARING HEREIN IS BASED UPON DATA OBTAINED FROM THE MANUFACTURER AND/OR RECOGNIZED TECHNICAL
SOURCES. WHILE THE INFORMATION IS BELIEVED TO BE ACCURATE, UNIVAR AND POLYSCIENCE MAKE NO REPRESENTATIONS AS TO ITS
ACCURACY OR SUFFICIENCY. CONDITIONS OF USE ARE BEYOND UNIVAR’S AND POLYSCIENCE’S CONTROL AND THEREFORE USERS ARE
RESPONSIBLE TO VERIFY THIS DATA UNDER THEIR OWN OPERATING CONDITIONS TO DETERMINE WHETHER THE PRODUCT IS SUITABLE
FOR THEIR PARTICULAR PURPOSES AND THEY ASSUME ALL RISKS OF THEIR USE, HANDLING, AND DISPOSAL OF THE PRODUCT, OR FROM THE
PUBLICATION OR USE OF, OR RELIANCE UPON, INFORMATION CONTAINED HEREIN. THIS INFORMATION RELATES ONLY TO THE PRODUCT
DESIGNATED HEREIN, AND DOES NOT RELATE TO ITS USE IN COMBINATION WITH ANY OTHER MATERIAL OR IN ANY OTHER PROCESS.
FOR ADDITIONAL INFORMATION
NOTICE
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