Page 1
Extended Rate Infuser
OPERATOR MANUAL
Page 2
Important User Information
CAUTION: Do not autoclave, steam sterilize, EtO sterilize, or
subject the MicroFuse Infuser to temperatures in excess of
40oC (104oF).
CAUTION: No user-serviceable parts inside. Refer all service,
repair and calibration to qualified technical personnel. Do not
make unauthorized modifications.
CAUTION: USA Federal and Canadian laws restrict this device to
sale by, or on the order of, a physician.
WARNING: Always ensure that medications delivered
simultaneously by the pump are compatible. Refer to the drug
manufacturers’ labeling when selecting drugs for use.
WARNING: Always purge the infusion lines between infusions of
two separate medications to avoid inadvertent infusion of
medication contained within the administration set or to avoid
inadvertent mixing of incompatible medications.
WARNING: Be sure that the syringe plunger is engaged by the
syringe driver arm when MicroFuse Infuser is connected to a
patient, to prevent siphoning.
WARNING: Purge the system of all air bubbles before
administering any medication. Failure to follow this normal
infusion procedure could result in patient injury.
USER INFORMATION
WARNING: Do not expose the pump to X-rays, gamma rays, or
other ionizing radiation, or to strong electric or magnetic fields.
WARNING: Do not operate the MicroFuse Infuser in the
presence of flammable anesthetics mixed with air or oxygen or
nitrous oxide.
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Page 3
Important User Information
WARNING: If an “OCCLUSION” alarm occurs, Immediately
disconnect the administration set at or above the
administration site to eliminate the possibility of a bolus
being delivered to the patient. Inspect the administration
set for kinks, closed stopcocks, clogged catheters, etc.
WARNING: Not for use with blood or blood products.
WARNING: Remember that the volume of fluid contained in
the connecting tubing is a residual amount and will not be
infused. Allow for this needed extra volume of fluid when
initially filling the syringe.
WARNING: This device must not be used in the presence of
Magnetic Resonance Imaging (MRI) machines.
WARNING: To prevent siphoning, make sure the flange of
the barrel is inserted in the barrel flange slot.
WARNING: Use only the syringes listed in the
specifications on page 14 of this manual. Failure to do so
many result in inaccurate delivery.
IMPORTANT: Carefully read the entire contents of this
manual before using the MicroFuse Infuser.
IMPORTANT: For safe disposal of administration sets and
syringes, refer to facility protocol.
IMPORTANT: The release date is on the back cover. If the
date is greater than two years, please contact Baxa
Corporation to see if additional information related to the
this product is available.
For Customer Support call 802-323-0101 • FAX 802-334-6971
USER INFORMATION
Page 4
Table of Contents
Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2
Syringe Compatibility . . . . . . . . . . . . . . . . . . .2
Description . . . . . . . . . . . . . . . . . . . . . . . . . .2
Applications . . . . . . . . . . . . . . . . . . . . . . . . .3
Contraindications . . . . . . . . . . . . . . . . . . . . . .3
Infuser Diagram . . . . . . . . . . . . . . . . . . . . . . .4
Basic Operation . . . . . . . . . . . . . . . . . . . . . . . . . . . .5
Features . . . . . . . . . . . . . . . . . . . . . . . . . . . .5
Operating Procedures . . . . . . . . . . . . . . . . . . .6
Technical Reference . . . . . . . . . . . . . . . . . . . . . . . .9
Infusion Time Charts . . . . . . . . . . . . . . . . . . .9
Occlusion Pressure Charts . . . . . . . . . . . . . . .13
Appendix . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .14
Specifications . . . . . . . . . . . . . . . . . . . . . . . .14
Maintenance . . . . . . . . . . . . . . . . . . . . . . . .15
Customer Support . . . . . . . . . . . . . . . . . . . . .17
Warranty . . . . . . . . . . . . . . . . . . . . . . . . . . .18
General Information . . . . . . . . . . . . . . . . . . . . . . .18
TABLE OF CONTENTS
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Page 5
Overview
The MicroFuse™ Extended Rate Infuser is intended for
small-volume infusion of intravenous drugs. Rate 1 allows a
bolus dose to infuse over 20 to 40 minutes, and over an
extended length of time can accommodate volumes up to 85
mL. Rate 2 will extend the infusion over 4 to 24 hours.
Infusion times on both rates are dependent on syringe size
and solution volume.
MicroFuse Extended Rate Infusers are:
• Durable – solid-body construction with secure motor
attachment
• Easy-to-use – simple push-button controls
• Portable – lightweight and slender profile
• Reliable – low maintenance, with built-in safety features
Syringe Compatibility
The MicroFuse Extended Rate Infuser is compatible with
Becton-Dickinson®(B-D), Monoject®and Terumo®disposable
syringes.
Description
The infuser operates on two standard alkaline C-cell
batteries. The syringe holder secures the syringe in place.
Once the infuser is turned ON, the syringe driver arm
depresses the plunger at a fixed rate, administering the
contents of the syringe through the administration tubing
and into the patient access site. A microprocessor control
operates at a constant delivery rate, and can infuse
syringe contents against a back pressure of ± 100 mm Hg.
The MicroFuse Extended Rate Infuser infuses at one of two
pre-set flow rates. RATE 1 (rabbit) infuses most doses over
20 to 40 minutes. RATE 2 (turtle) rate infuses most
therapies over 4 to 24 hours.
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INTRODUCTION
2
Page 6
Description (continued)
The MicroFuse Extended Rate Infuser has a full complement of
alarms, which signal: end of infusion, occlusion detection, low
battery, maintenance required, and internal malfunction. Alarms
are indicated by flashing status lights and an audible chime.
NOTE: Audible alarms may be placed in MUTE mode by pressing
Alarm Mute switch for two full seconds.
WARNING: Federal and Canadian law restricts this device to sale,
distribution, and use by, or on the order of, a licensed practitioner.
Applications
Use the MicroFuse Extended Rate Infuser for the following
types of intermittent and continuous infusion therapies:
1. Extended infusion of other drugs for periods of 4 to 24
hours, depending on syringe size and solution volume.
2. Primary intermittent infusion through a heparin or saline
lock.
3. Piggyback through a primary IV line. Primary line flow rate is
not interrupted. The infuser administration set is attached to
the primary line at the lower injection port or flashball site.
4. Piggyback with an IV controller or IV pump. No change is
required for the pump or controller. The administration set
is attached to the primary line at an injection port or a
flashball site downstream from the primary infusion device.
5. Piggyback in combination with a volume control chamber
(burette). Burette flow rate is not interrupted. The
administration set is attached to the primary line at either
the lower injection port or the flashball site.
Contraindications:
The MicroFuse Infuser is not for use in the presence of
INTRODUCTION
explosive anesthetics.
NOTE: See Infusion Time Charts to determine appropriate fluid
volume and syringe combinations to achieve extended
infusions up to 24 hours.
3
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Page 7
Infuser Diagram
Mute
Alarm
Indicator
Alarm
Audible
Rate 2
Indicator
Flow Rate
Rate
Flow
Rate 1
Indicator
Flow Rate
Flange
Syringe
Switch
Switch
Slot
Syringe Driver Arm Flange
Alarm Indicator
Wire Hanger
Low Battery Indicator
Battery Caddy
IV Pole Clamp Mounting Bolts
(Remove to attach pole clamp)
Serial Number
Syringe Barrel Holder
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Switch
ON/OFF
INTRODUCTION
4
Page 8
Features – Light Indicators
+
-
The MicroFuse Extended Rate Infuser uses five status
indicator lights:
Indicator Status
Rate 1 Flashes GREEN when Flow Rate is set to Rate 1
Rate 2 Flashes YELLOW when Flow Rate is set to Rate 2
Low Battery Flashes RED when batteries need to be changed
Alarm Flashes RED when an alarm condition is detected
Alarm Mute Flashes YELLOW when the audible alarm is muted
NOTE: If the infuser detects an internal malfunction, the audible
alarm always sounds, regardless of the Alarm Mute status.
Features—Alarms
Audible alarms accompany RED status indicator lights:
Condition Light & Chime Indicators
Action Required
End of Infusion/
Occlusion
Internal
Malfunction
BASIC OPERATION
Low Battery/
First 10 hours
at Rate 1
Low Battery/
After 10 hours
at Rate 1
NOTE: The infuser will continue to operate for approximately
10 hours at Rate 1 after a low battery condition is first
detected. After 10 hours, the infuser will not function and
will sound an alarm.
5
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Slow flashing ALARM light
with slow two-tone CHIME
sound.
Rapid flashing ALARM light
Rapid CHIME sound.
Multi-note CHIME when Power
is first switched ON. LOW
BATTERY light will continue
to flash during an infusion
when the batteries are low.
Repeating multi-note CHIME
and infuser will not function.
Turn infuser OFF, or leave
infuser ON and press ALARM
MUTE switch. If an alarm
occurs, and infusion is not
complete, the IV set or
catheter may be occluded.
If an occlusion occurs, clear
it and restart the infuser.
Turn infuser OFF, then ON.
If alarm reappears, contact
Customer Support. ALARM
light remains lit when unit
is OFF.
Change batteries as soon
as possible.
Batteries must be changed.
Page 9
Operating Procedures
Follow accepted IV therapy techniques and procedures when
setting up and administering intermittent or continuous IV
therapy with the MicroFuse Infuser.
A. Setup
• Eliminate any air from syringe.
• Connect an IV administration set to the drug syringe.
NOTE: Administration set should be 6 to 60 inches long with
an internal diameter (ID) between 0.020 and 0.030 inches. A
tubing clamp is desired, but not required.
• Prime administration set to ensure that air is eliminated
from the syringe and tubing.
B. Install Syringe
1. Load the syringe into the infuser by sliding it underneath the
syringe barrel holder. Alternately, pull open the barrel holder
and place syringe on the infuser.
2. Position the syringe barrel flange in the syringe barrel flange
slot on the infuser body.
3. Position the syringe plunger in the slot on the syringe driver
arm.
Syringe
Barrel
Holder
Syringe
Flange
Slot
Syringe
Driver
Arm
WARNING: The syringe driver arm can be moved only when the
Power ON/OFF switch is fully in the OFF position. Syringe plunger
must be secured in the slot of the syringe driver arm. If plunger
is not properly secured, or unit is not completely turned OFF,
gravity flow may occur when the infuser is hanging above the
patient. This may cause a delay or failure to deliver when the
switch is placed in the ON position.
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BASIC OPERATION
6
Page 10
C. Select Flow Rate
Use the infuser scales to read an approximate time to infuse
a specific dose. Check the Infusion Time Charts in the
Technical Reference section for actual flow rates.
1. To check the infusion flow rate, press FLOW RATE switch.
This can be done with the infuser power off.
2. To change rate, hold the FLOW RATE switch for two full
seconds. RATE 1 will flash green, RATE 2 will flash yellow.
RATE 1 infuses a bolus dose (ex: cefazolin 1 gram in 10
mL) over 20 to 40 minutes. RATE 2 infuses recommended
doses over 4 to 24 hours.
NOTE: See page 17 for procedure to make the MicroFuse
Infuser a single-rate infuser.
Administration
1. Attach the administration set to the patient infusion site.
2. Secure the MicroFuse Infuser to avoid unnecessary
movement at the infusion site.
• Hang the infuser from an IV pole using the attached
wire hanger.
• Attach the infuser to the IV pole using the optional IV
Pole Clamp.
3. Begin the infusion cycle by sliding the ON/OFF switch to
ON.
4. When the infuser is turned ON it will:
• Flash all alarm and status indicators.
• Produce an audible CHIME.
• Perform an internal self-check of the microprocessor
and battery power level.
BASIC OPERATION
• Rate indicator light will flash during the entire infusion.
5. Press the ALARM MUTE switch for two full seconds to
deactivate the audible CHIME, if desired.
NOTE: If any malfunction or alarm condition is detected,
a CHIME will sound. Refer to the Features section for
detailed descriptions. If an alarm occurs, and infusion is
not complete, the IV set or catheter may be occluded. If
an occlusion occurs, clear it and restart the infuser.
7
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Page 11
Administration (continued)
6. When the infusion is complete, the ALARM flashes. A CHIME
is sounded unless the ALARM MUTE switch is activated.
Alarm verifies end of infusion has been detected.
7. To leave the infuser in place until the next use:
• Clamp the IV line and slide the ON/OFF switch fully to
OFF. This turns off all alarm functions and releases the
pressure on the syringe plunger.
8. To remove the syringe after infusion is complete, lift the
syringe barrel holder and slide the syringe out of the infuser.
CAUTION: Releasing pressure on the syringe plunger can allow
small amounts of the primary IV solution to be pumped back
up the extension set and into the syringe. This situation can
occur when the Infuser is OFF and an upstream infusion device
is pumping the primary IV solution down the primary tubing.
See notes on preventing fluid backflow.
Preventing Fluid Backflow
• When End of Infusion Alarm occurs, leave the infuser Power
ON and press the ALARM MUTE switch. This will turn off
audible alarms and leave the syringe driver arm locked in
place.
• Clamp the MicroFuse Administration Set with the attached
slide clamp.
• Use a primary tubeset with a back check valve prior to the
secondary set attachment.
Procedural Notes:
• Always follow accepted IV therapy techniques when clearing
occlusions and removing syringes and administration sets
from the patient infusion site.
• Infuser may be turned OFF and infusion restarted at any
time without affecting the infusion rate or accuracy.
• Administration set change interval should meet accepted
facility policy.
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BASIC OPERATION
8
Page 12
Advantages to Using a MicroFuse Extended Rate Infuser
for Continuous Infusion
• Save material costs – Use inexpensive syringes instead
of costly ambulatory infusion pumps, tubings and bags
as with CADD setups; less need for expensive full-size
infusion pumps.
• Simplicity – Few infusion devices are easier to learn and
use.
• Convenience – Use generic microbore sets versus
dedicated disposables.
Infusion Time Charts
These charts provide a simple method to determine:
infusion time, solution volume, and syringe size.
To use the Charts:
1. Select the appropriate chart by defining the desired flow
rate (1 or 2) and the brand of syringe.
2. Select two of the three variables: solution volume,
infusion time or syringe size.
3. Cross-reference the two selections on the chart to locate
the third unknown variable.
Example (Monoject®60 cc syringe)
1. For a Monoject syringe, use Chart #2
TECHNICAL REFERENCE
9
2. Flow Rate: 2
3. Solution volume: 45 mL
4. 45 cc indicates
Time to infuse: 24 hours
NOTE: The infusion time labels located on the MicroFuse
Infuser are approximate. The actual infusion time for a given
solution volume and syringe size should be determined from
the Infusion Time Charts.
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Page 13
Infusion Time Charts
0
10
20 30 40 50 60 70 80 90 100
5
10 15 20 25 30 35
5101520
1
23456 7 8 9 10 11 12
1
2345
6
105
15
20 3025
35
40
45 minutes
140 cc
35 cc
20 cc
12 cc
6 cc
Infusion Time
Syringe Size
Volume Infused
105
10 20 30 40 50
60 cc
55
0
10 20 30 40
5
10 15 20 25 35
5101520
1
2345678910
1
234
5
93
15 18 24 hours21
60 cc
35 cc
20 cc
12 cc
6 cc
Infusion Time
Syringe Size
Volume Infused
45 cc
126
30
11 12
6
10 20 30 40
140 cc
85 cc
50 60 70 80
Chart #1: Monoject Syringes – Rate 1
Chart #2: Monoject Syringes – Rate 2
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TECHNICAL REFERENCE
10
Page 14
Infusion Time Charts
0
10 20 30 40
5
10 15 20 25 30
5101520
1
2345678910
1
234
5
93
15 18 24 hours21
60 cc
30 cc
20 cc
10 cc
5 cc
Infusion Time
Syringe Size
Volume Infused
45 cc
126
0
10 20 30 40 50
5
10 15 20 25 30
5101520
1
2345678 910
1
234
5
105
15
20 3025
35
40
45 minutes
60 cc
30 cc
20 cc
10 cc
5 cc
Infusion Time
Syringe Size
Volume Infused
55
Chart #3: B-D Syringes – Rate 1
Chart #4: B-D Syringes – Rate 2
TECHNICAL REFERENCE
11
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Page 15
Infusion Time Charts
0105
15
20 3025
35
40 minutes
Infusion Time
Syringe Size
Volume Infused
10 20 30 40 50 60
5
10 15 20 25 30 35
5101520
1
2345678 910
1
2345
6
60 cc
30 cc
20 cc
10 cc
5 cc
25
11
12
0
10 20 30 45
5
10 15 20 25 30
51015 25
1
234567 8910
1
234
5
93
15 18 24 hours21
60 cc
30 cc
20 cc
10 cc
5 cc
Infusion Time
Syringe Size
Volume Infused
50 cc
126
40
20
6
Chart #5: Terumo Syringes – Rate 1
Chart #6: Terumo Syringes – Rate 2
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TECHNICAL REFERENCE
12
Page 16
Occlusion Pressure Charts
These charts indicate the pressure exerted by the infuser
when an occlusion alarm occurs. When the infuser is OFF,
the pressure is released from the syringe driver arm.
To determine the typical occlusion pressures for a specific
syringe:
1. Select the proper chart for brand of syringe.
2. Select the syringe size.
3. Read the resulting typical occlusion pressures from the
table.
Occlusion Pressure Charts
Monoject
Syringes
Syringe (cc)
Typical Pressure, psig
The Monoject 140 cc
*
syringe requires the
use of a smallbore
(0.05") extension set
to prevent false
occlusion alarms.
Terumo
TECHNICAL REFERENCE
Syringes
Syringe (cc)
5
10
20
30
60
Typical Pressure, psig
30
24
27
16
11
NOTE: Excessively viscous solutions (e.g., D25W) may cause
false occlusion alarms under some delivery conditions.
6
12
20
35
60
140* 9
B-D
Syringes
Syringe (cc)
5
10
20
30
60
Typical Pressure, psig
28
22
23
20
14
36
24
24
21
15
13
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Page 17
Specifications
Size (L, W, H): . . . . . . . . . . .9.6 in x 2.7 in x 4.0 in
(24.4 cm x 6.9 cm x 10.1 cm)
Weight: . . . . . . . . . . . . . . . .25 oz. (0.7 kg) with batteries,
20 oz. (0.6 kg) without
Storage Temperature . . . . . .14°F to 149°F
(-10°C to 65°C)
Materials of Construction: . .Injection-molded plastic housing,
battery cover, syringe driver arm
and syringe holder
Compatible Syringes: . . . . . .BD, Monoject, and Terumo
disposable syringes
Syringe Sizes: . . . . . . . . . . .5 to 140 cc
Accuracy of Flow Rate: . . . . .3% over 1.18 in (29.97 mm)
Power Requirement: . . . . . . .3.0 V dc (battery only)
Batteries: . . . . . . . . . . . . . .Two (2) C-cell, alkaline only
Infusion Rates: . . . . . . . . . .Rate 1: 5.5 in/hr, 14 cm/hr
Rate 2: 0.133 in/hr, 0.338 cm/hr
Delivery Times: . . . . . . . . . .Rate 1: 20 to 40 minutes
(for most applications) Rate 2: 4 to 24 hours
See the Infusion Time Reference
Charts for flow rates with specific
syringes.
Occlusion Pressure: . . . . . . .< 45 psi, (2327 mm Hg), See the
Occlusion Pressure Reference
Charts for typical occlusion
pressures with specific syringe
sizes.
Back Pressure Effect: . . . . . .None within 100 mm Hg
pressure
Mounting Options: . . . . . . . .Built-in wire hanger or optional
IV Pole Clamp
Alarms: . . . . . . . . . . . . . . . .Occlusion, end of infusion, low
battery, return for maintenance,
and internal malfunction
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APPENDIX
14
Page 18
Maintenance
The MicroFuse Extended Rate Infuser is designed to require
little maintenance. On activation, the infuser checks all major
functions. Cleaning, disinfection and inspection should be
performed according to users’ standard protocols.
EMI Interference
The MicroFuse Extended Rate Infuser is designed to
operate normally in the presence of most encountered
electromagnetic field conditions. In the event of extreme
levels of interference, normal operation may be disrupted.
Cleaning and Disinfection
Do not use harsh or aggressive cleaners such as concentrated
bleach or ammonia. They may cause degradation of the unit
and void the unit warranty! Exterior infuser surfaces may be
cleaned using a damp cloth and mild detergent. Use either
ispropyl alcohol 70% or dilute germicidal bleach to disinfect.
The infuser cannot be immersed or flushed with any solution.
Do not sterilize using EtO gas or steam autoclave.
Battery Replacement
The MicroFuse Extended Rate Infuser operates with two Ccell alkaline batteries. To access batteries, unlock caddy at
the side of the unit and squeeze. Caddy will pull out. Load
new batteries into the holders according to the orientation
indicated. Replace the battery caddy.
APPENDIX
15
Inspection
If the infuser has been dropped or damaged, inspect the
unit before use.
• Look for visible cracks or breaks in the case.
• Inspect the battery housing for damage.
• Batteries must fit in the battery caddy, and the caddy
must seat snugly into the infuser body.
• Turn power ON and verify that the syringe driver arm is
locked into position.
• Run a Flow Rate Test to verify delivery accuracy.
CAUTION: Dropped infusers may incur internal damage.
Refer to the instructions above to check for unit damage.
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Page 19
Flow Rate Test
The rate of travel of the syringe driver arm may be tested as
follows:
1. Set the FLOW RATE switch to Rate 1.
2. Set the syringe driver arm as far toward the hanger as
possible (maximum travel).
3. Slide the Power ON/OFF switch to ON.
4. Time until the End of Infusion alarm occurs. The time
should be 44 to 47 minutes.
NOTE: Always replace both batteries at the same time with
fresh batteries. Be careful to load both batteries in the
correct orientation.
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APPENDIX
16
Page 20
Rate Lock Out
To restrict the MicroFuse Extended Rate Infuser to a single
infusion rate:
Set desired infusion rate using the FLOW RATE switch. Either
Rate 1 or 2 can be locked. Release and remove battery
caddy. Slide the LOCK/ UNLOCK switch in the battery
compartment to LOCK. This fixes the FLOW RATE at the
selected rate. Replace the battery caddy. Switch to UNLOCK
to allow rate selection again.
Customer Support
If the infuser malfunctions, or is defective for any reason, it
should be returned to an authorized agent.
Contact Customer Service (802-323-0101) for a Returned Goods
Authorization (RGA) number and shipping instructions. Please
have the following information available:
• Infuser serial number • Reason for the return
Freight is prepaid. Shipping weight: 2 lb.
2 oz. (when returned in the foam-lined infuser box).
Goods returned without an RGA will be refused.
Ship to: Numia Medical Technology
84 Farrant Street
Newport, VT 05855
APPENDIX
17
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Page 21
General Information
New Product Program
Most of the products we offer were made because of
customer suggestions. We welcome your suggestions for new
products and improvements on existing products.
Product Warranty
The Limited Warranty provided with the purchase of the
MicroFuse Extended Rate Syringe Infuser covers defects in
materials or workmanship for a period of 12 months from the
date of purchase. This Warranty does not cover failures due
to negligence or misuse.
Numia Medical Technology may, at its sole discretion,
exchange the infuser for another that is in good working
order. The MicroFuse Infuser is warranted to perform in
accordance with published specifications and information.
This is an exclusive warranty. Any remedies under this
warranty are restricted to replacement of defective product.
Numia Medial Technology is in no way liable for incidental or
consequential damages.
Ordering Information
To order MicroFuse Extended Rate Infusers and
accessories:
Contact Numia Medical Technology:
Phone: 802-323-0101
Fax: 802-334-6971
For Customer Support call 802-323-0101 • FAX 802-334-6971
APPENDIX
18
Page 22
Notes
19
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Page 23
Notes
For Customer Support call 802-323-0101 • FAX 802-334-6971
20
Page 24
6400-IFU-0006 Rev.C
Numia Medical Technology, LLC
84 Farrant Street
Newport, VT 05855
tel: 802-323-0101
fax: 802-334-6971
Manufactured by:
www.numiamedical.com
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