International Call 703-527-3887 (collect calls accepted)
2. Composition and Information on Ingredients
CAS #SARA 313 Material or ComponentExposure Limits
On? Dm* % RQ#TWA*STEL*WEEL*
71-23-8NoNA1-Propanol A330None200 ppm 400 ppm NA
All health and safety information given herein refers to 1-propanol.
No component is listed in "Threshold and Biological Exposure Indices for 2004" from ACGIH except as noted above. Components listed
in Title III Sec. 313 (EPCRA) are indicated by "Yes" above. *TWA= Time Weighted Average; STEL= Short Term Exposure Limit;
WEEL= Workplace Employee Exposure Level; NE= Not Established A4= Not Classifiable as a Human Carcinogen
BEI+ Biological Exposure Index exists for this material. Dm= De minimus A3 = Confirmed Animal carcinogen with Unknown Relevance to Humans
3. Hazards Identification
OSHA Hazard Classification:
Has a 96'F Flash Point but does not support combustion.
Ref: 49 CFR 173.120(a)(3) for DOT exemption from "Flammable Liquid" classification.
Routes of Entry:Skin, eyes, Inhalation, ingestion
Chemical Interactions:Avoid contact with all oxidizing agents, acids, acid chlorides, acid anhydrides, halogens,
aluminum and aluminum alloys.
Medical Conditions Aggravated:No information.
Human Threshold Response Data
Odor Threshold: Not establishedIrritation Threshold: Not established
Hazard Category Classifications and Ratings
Hazard Categories: Health Fire Pressure Reactivity Reference 49 CFR 171.8,
ImmediateYesYesNoNo OSHA 29 CFR 1910.1200 and
DelayedNoNoNoNo SARA 302/311/312/313.
HMIS Hazard Ratings: Health 1 Fire 1 Instability 0 Other B (Goggles, gloves)
NFPA 704 Hazard Ratings: Health 1 Flammability 1 Reactivity 0 Special NA
Hazard Ratings: Least: 0 Slight: 1 Moderate: 2 High: 3 Extreme: 4
Notice: HMIS and NFPA ratings involve the subjective evaluation of the hazardous aspects of individual components, and can differ between
preparers. They are intended and useful only as a rapid, general identification of the approximate magnitude of the specific hazards rated
Immediate (Acute) Health Effects
Inhalation Toxicity: Harmful if inhaled or swallowed.
Inhalation Irritation:High concentrations or prolonged exposure can cause headaches, dizziness and nausea .
Skin Contact:Skin contact may cause irritation from dehydration and de-fatting of the skin.
Skin Absorption:No immediate responses.
Eye ContactLiquid and vapor cause eye irritation, tearing and a burning sensation.
Ingestion Irritation:Irritating.
Ingestion Toxicity:Almost non toxic. See Sec. 11.
Acute Target Organ Toxicity:Kidneys, liver, central nervous system.
Prolonged (Chronic) Health Effects
Carcinogenicity:Rated A3 = Confirmed Animal carcinogen with Unknown Relevance to Humans.
Reproductive and Developmental Toxicity:Mutagenic effects were noted in animal studies.
Sensitization:None known.
Inhalation:Prolonged or repeated exposure may cause more severe irritation. May cause pulmonary edema
(fluid build-up in lungs). See also Inhalation entry above.
Skin Contact:Prolonged or repeated skin exposure may cause dermatitis.
Skin Absorption:Chronic exposure may cause liver damage.
Ingestion:Chronic ingestion unlikely. See Acute entry above. Can lead to liver damage.
General :Prolonged or repeated exposure may cause all acute toxic symptoms described above.
Chronic Target Organ Toxicity:Liver
Supplemental Health Hazard Information:No additional health information available.
Inhalation:Remove individual to fresh air. If not breathing, give artificial respiration or oxygen as appropriate.
Seek medical attention at once.
Skin Contact:Flush skin with water for 15 minutes and remove contaminated clothing.
Wash shoes and clothing before reuse.
Eyes:Immediately flush eyes with plenty of water for at least 15 minutes while holding eyelids apart.
Ingestion:Immediately drink water to dilute. Induce vomiting. Consult a physician immediately.
Never give anything by mouth to an unconscious person.
5. Fire Fighting Measures
Flammability Summary (OSHA):
Extremely flammable.
Flammable Properties:
Flash Point:96F
Autoignition Temperature:ND
Upper Flammable/Explosive Limit, % in a 13.5 for 1-propanol
Lower Flammable/Explosive Limit, % in a 2.1 for 1-propanol.
Fire/Explosion Hazards Vapor can travel distances to ignition sources and flash back.
Hot organic chemical vapors or mists are susceptible to sudden spontaneous combustion when mixed with air.
Ignition may occur at temperatures below published autoignition or ignition temperatures. Ignition temperatures
decrease with increasing vapor volume and vapor/air contact time and are influenced by pressure changes.
Ignition may occur at typical elevated temperature process conditions, especially in processes operating
under vacuum if subjected to the sudden ingress of air, or with sudden escape of hot vapors into outside air.
Extinguishing Media:
Does not support combustion. Use equipment appropriate to the main cause of the fire.
Do not allow contaminated water to enter sewers or waterways.
Fire Fighting Instructions:
Does not support combustion. Use equipment appropriate to the main cause of the fire.
Use water to cool containers.
Hazardous Combustion Products:
Oxides of carbon.
6. Accidental Release Measures
Personal Protection for Emergency Situations:
Evacuate the area of all unnecessary personnel. Eliminate any ignition sources.
Contain the release and eliminate its source if this can be done safely.
Spill Mitigation Procedures
Air Release:
Hazardous concentrations in air may be found in local spill area and immediately downwind. Vapors may
be suppressed by the use of water fog. Contain all liquid for treatment and/or disposal as a (potential)
hazardous waste. Do not flush to sewer! US regulations (CERCLA) require reporting spills and releases to soil,
water and air in excess of stipulated quantities. US Coast Guard National Response Center is 800-424-8802.
Water Release:
This material is soluble in water. Contain all liquid for treatment and/or disposal as a (potential) hazardous
waste. Notify all downstream users of possible contamination.
Land Release:
Create a dike or trench to contain materials. Absorb spill with inert material (e.g., dry sand, clay, earth or
commercial absorbent), then place in a chemical waste container.
Contain all contaminated water for disposal and/or treatment.
Additional Spill Information:
Stop source of spill as soon as possible and notify appropriate personnel. Utilize emergency response
personal protection equipment prior to the start of any response. Evacuate all non-essential personnel.
Dispose of spill residues per guidelines under Section 13, Disposal Considerations.
Handling: Use with adequate ventilation. Vent containers before opening wide.
Do not take internally. Avoid contact with skin, eyes and clothing. Upon contact with skin or eyes, wash
with water. Avoid breathing vapor, mist or gas.
Retained residue may make empty containers hazardous. USE CAUTION!
Storage
Keep container closed when not in use. Store in a cool area away from ignition sources and oxidizers.
Shelf Life Limitations:
See label or certificate of analysis for shelf life if applicable.
Incompatible Materials for Storage:
Refer to Section 10, "Incompatible Materials."
8. Exposure Controls and Personal Protection
Ventilation:
Local exhaust ventilation or other engineering controls are normally preferred when handling or using this
product. Otherwise, use general exhaust ventilation if that is sufficient for general worker safety and comfort.
Explosion proof motors and fans are required. A NIOSH/MSHA approved air supplied respirator is advised in the
absence of adequate environmental control.
Protective Equipment for Routine Use of Product
Respiratory Protection:
See previous paragraph. Material should be handled or transferred in an approved fume hood or with adequate
ventilation.
Respirator Type(s):
Air purifying respirators should not be used in oxygen deficient or IDLH atmospheres or if exposure
concentrations exceed ten (10) times the published limit.
Skin: Wear impervious gloves (butyl rubber, Viton, e.g.) to avoid skin contact. Follow good industrial hygiene practices.
Eyes: Use chemical safety glasses with side shields, safety goggles and/or a full face shield where splashing is possible.
Protective Clothing Type: Impervious
Other: A safety shower and eye bath should be readily available.
Exposure Limit Data : See Section 2
Chemical Name: NIOSH Level Immediately Dangerous to Life or Health:
Conditions to Avoid:High temperatures, exposure to heat.
Chemical Incompatibility:see Sec. 3.
Incompatible materials:May attack some rubbers and plastics.
Hazardous Decomposition Products: CO, CO2
Decomposition Temperature:No data
Product May Be Unstable At Temperatures Above:No data
11. Toxicological Information
Component Animal Toxicology for 1-propanol
Oral LD50 mg/kg value: 6800 (mus); 1870 (rat); 2825 (rbt)
Dermal LD50 mg/kg value:4050 (rbt)
Inhalation LC50 ppm value:48,000 mg/m3 (mus)
Product Animal Toxicity: See above
Skin Irritation:This material is expected to be moderately irritating.
Eye Irritation:This material is expected to be moderately irritating.
Reproductive and Developmental Toxicity:Has been found in animal studies.
Component Data:All data refer to 1-propanol.
Mutagenicity:Has been found in animal studies.
Carcinogenicity:Rated A3 = Confirmed Animal carcinogen with Unknown Relevance to Humans.
Page 4 of 4
12. Ecological Information
Ecological Toxicity Values:
Dangerous to aquatic life in high concentrations.
Environmental fate:No potential for food chain concentration.
Environmental Toxicity: No data.
13. Disposal Considerations
No data provided.
14. Transportation Information
No data provided.
15. Regulatory Information
No data provided.
16. Additional Information
THE PURPOSE OF THIS MSDS IS TO PROVIDE SAFE HANDLING INFORMATION FOR USERS OF THE PRODUCT
IT IS NOT INTENDED TO, NOR DOES IT, PROVIDE COMPLETE OR EXTENSIVE TRANSPORTATION, DISPOSAL, REGULATORY
OR TOXICOLOGICAL DATA ON THE PRODUCT OR ITS COMPONENTS. USERS WHO REQUIRE THIS INFORMATION ARE
REFERRED TO RELEVANT LOCAL, STATE AND FEDERAL REGULATIONS FOR THE INGREDIENTS OF INTEREST.
THIS MATERIAL SAFETY DATA SHEET (MSDS) HAS BEEN PREPARED IN COMPLIANCE WITH THE FEDERAL OSHA HAZAR
COMMUNICATION STANDARD, 29 CFR 1910.1200. THE INFORMATION IN THIS MSDS SHOULD BE PROVIDED TO ALL WHO
WILL USE, HANDLE, STORE, TRANSPORT, OR OTHERWISE BE EXPOSED TO THIS PRODUCT. WE BELIEVE THIS
INFORMATION TO BE ACCURATE, RELIABLE, AND UP TO DATE, BUT MAKE NO WARRANTY THAT IT IS.
IF THIS MSDS IS MORE THAN THREE YEARS OLD YOU SHOULD CONTACT THE SUPPLIER TO MAKE CERTAIN THAT THE
INFORMATION IS CURRENT.
THE POSSESSOR OF THIS MATERIAL HAS THE RESPONSIBILITY TO INSURE THAT IT IS USED, HANDLED, STORED
TRANSPORTED AND DISPOSED OF IN COMPLIANCE WITH ALL RELEVANT LOCAL, STATE AND FEDERAL REGULATION
MSDS data source: Alfa-Aesar 7/03/2001
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