Composition, Information on Ingredients, Exposure Limits
LD50 or LC
50
Route/Species
Refrigerant R-404A
44% Pentafluoroethane
CAS# 354-33-6
52% 1, 1, 1-Trifluoroethane
CAS# 420-46-2
4% 1,1,1,2-Tetrafluoroethane
CAS# 811-97-2
0.0001% to 1.0%
1 PPM to 10,000PPM
Not Available
Du Pont
Acceptable
Exposure Level
(AEL) is 1000 ppm
8 & 12 hour TWA
Pentafluoroethane LC50:
>800,000 ppm inhalation rat
(4 Hr)
1,1,1-Trifluoroethane LC50:
>540,000 ppm inhalation rat
(4 Hr)
1,1,1,2-Tetrafluoroethane
LC50: >500,000 ppm
inhalation rat (4 Hr)
Nitrogen
Formula: N2
CAS: 7727-37-9
RTECS#: QW9700000
Emergency Contact: Chemtrec (800) 424-9300
Or Norco (208) 336-1643
R-404A 0.0001% to 1% in Nitrogen
M A T E R I A L S A F E T Y D A T A S H E E T
1125 West Amity Road
Boise, ID 83705
(208) 336-1643
Product Name: R-404A in Nitrogen Revision Date: 03/19/13
Last Review Date: 03/19/13
Chemical Name: R-404A (44% Pentafluoroethane, 52% 1, 1, 1-Trifluoroehtane, 4%, 1, 1, 1, 2-Tetrafluoroethane) in Nitrogen
Chemical Family: Gas Mixture
CAS Number: N/A
Common Names/Synonyms: Calibration Gas Mixture
MSDS Identification Code/Number: #4090
Prepared by: Quality Dept.
Exposure Limits
1
Refer to individual state or provincial regulations, as applicable, for limits that may be more stringent than those listed here.
2
As stated in 29 CFR 1910, Subpart Z (revised July1, 1993)
3
As stated in the ACGIH 2007 Threshold Limit Values for Chemical Substances and Physical Agents
1
OSHA Regulatory Status: This material is classified as hazardous under OSHA regulations.
Emergency Overview:
Simple Asphyxiant-This product does not contain oxygen and may cause asphyxia if released in a confined area. Colorless, nonÂflammable gas with a possible faint sweetish odor. High concentrations may cause nausea, dizziness and headaches. Repeated or
prolonged skin contact may cause irritation or dermatitis. Use only with adequate ventilation. Contents under pressure. Use and store
below 125OF (52OC).
Route of Entry:
NorLab, R-404A 0.0001% to 1.0% in Nitrogen, Material Safety Data Sheet #4090, Page 2 of 5
Hazards Identification Continued
Synergistic Effects:
None reported
Health Effects:
Carcinogenicity: NTP: No IARC: No OSHA: No
Eye Effects:
May cause minor irritation. Contact with rapidly expanding gas near the point of release may cause frostbite.
Skin Effects:
Liquid R-404A can cause a defatting action on the skin. Prolonged or repeated contact may tend to dry and defat skin causing
irritation and dermatitis. Contact with rapidly expanding gas near the point of release may cause frostbite with redness, skin color
change to gray or white, and blistering.
Ingestion Effects:
None known. Ingestion is unlikely as product is a gas at room temperature.
Inhalation Effects:
High concentrations of R-404A vapors may cause cardiac arrhythmia. Large releases of this product may displace atmospheric
oxygen resulting in asphyxiation. Symptoms of asphyxiation include loss of coordination, increased pulse rate and deeper
respiration.
Medical Conditions Aggravated by Exposure: None known.
NFPA Hazard Codes HMIS Hazard Codes Ratings System
Health: 0 Health: 0 0: No Hazard
Flammability: 0 Flammability: 0 1: Slight Hazard
Instability: 0 Physical Hazards: 3 2: Moderate Hazard
3: Serious Hazard
4: Severe Hazard
Ratings were assigned in accordance with Compressed Gas Association (CGA) guidelines as published in CGA Pamphlet P-19 2009
CGA Recommended Hazard Ratings for Compressed Gases, 3rd Edition.
Eyes:
Flush eyes with water for 15 minutes. If irritation persists or frostbite occurs, seek medical attention.
Skin:
Rinse skin thoroughly with water. For skin, immerse skin in lukewarm water. DO NOT USE HOT WATER. For frostbite or
persistent irritation, seek medical attention.
Ingestion:
None required. Product is a gas at normal temperatures and conditions.
Inhalation:
PROMPT MEDICAL ATTENTION IS MANDATORY IN ALL CASES OF OVEREXPOSURE. RESCUE PERSONNEL
SHOULD BE EQUIPPED WITH SELF-CONTAINED BREATHING APPARATUS. Victims should be assisted to an
uncontaminated area and inhale fresh air. Quick removal from the contaminated area is most important. Unconscious persons should
be moved to an uncontaminated area, and if breathing has stopped, administer artificial resuscitation and supplemental oxygen.
Further treatment should be symptomatic and supportive.