New Era NE-300 User Manual

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Model: NE-300

“Just Infusion”™

NE-1000 Series of Programmable Syringe Pumps

e t

n o

s u

0 10 20 30 40 50 60 70 80 90

Time

“WHAT’S YOUR APPLICATION?”™

WARNING

NOT FOR CLINICAL

USE ON HUMANS

Doc: 1200-02 Copyright New Era Pump Systems Inc. Rev. 14 V3.9 08/27/14

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New Era Pump Systems Inc.

www.SyringePump.com

Model NE-300 Syringe Pump

Quick Start Instructions

• Plug in the pump.

• Press the power switch to turn on power.

• Press any key to stop the display from blinking.

Setup Pumping Parameters

To Change Numbers:

• Use the arrow keys to increment individual digits.

•

To set or clear the decimal point:

decimal point position. Or, press and hold the left-most up-arrow key for at least 1 second. When the digit increments from 9 to 0, the decimal point will begin to shift. Release the key when the decimal point is correct.

• Press any non-arrow key, or wait 2 seconds, to enter the new setting. The display will blink when a new value is

entered and stored in memory.

Set the Syringe Inside Diameter:

• Momentarily press the ‘Diameter’ key. Set the inside diameter of the syringe in millimeters (mm).

Set the Pumping Rate.

• Momentarily press the ‘Rate’ key.

• To change the

− Momentarily press the ‘Rate’ key again. The display will show:

− While the units are blinking, press any arrow key to select the next available rate units.

− Press any non-arrow key, or wait 2 seconds, to set the rate units.

• Set the pumping rate. If the pumping rate is out of range, the display will show:

pumping rate units

Simultaneously press the 2 up-arrow keys under the 2 digits next to the

Load the Syringe

• Press in the white drive-nut button to move the pusher block.

• Lift and turn the syringe clamp away from the syringe holder block

• Position the syringe on the pump with the flange to the left of the syringe holder block.

• Lift and turn the syringe clamp onto the syringe body.

• Move the pusher block next to the syringe plunger.

Purge:

Press and hold the ‘Start/Stop’ key for one second. Release to stop.

Press and hold the direction button to reverse the pump and release the pusher block if

jammed.

Start the Pump:

Press and release the ‘Start/Stop’ key to start or stop the pump.

When Pumping

• The pumping rate can be changed.

PUMP RESET:

PUMP RESET:PUMP RESET:

Press and hold the right-most up-arrow key while turning on power to the pump.

Need more pumping features?

Visit www.SyringePump.com to see our full-featured syringe pumps.

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New Era Pump Systems Inc.

Table of Con

tents

GENERAL INFORMATION AND PACKING LIST .................................................... 1

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Model NE-300 Syringe Pump

1.1 W

1.2 D

2.1 G

5.1 E

5.2 LCD D

5.3 LEDS ................................................................................................................................ 5

5.4 UP A

5.5 ‘D

5.6 ‘R

5.6.1 P

5.7 ‘V

5.7.1 C

5.7.2 C

5.8 R

5.9 ‘S

5.10

5.11

5.11.1 F

5.11.2 R

5.12

ARNINGS! AND CAUTIONS

ISCLAIMER AND WARRANTY

OVERVIEW ....................................................................................................................... 2

LOSSARY OF TERMINOLOGY AND CONCEPTS

SETUP ................................................................................................................................. 3

LOADING SYRINGES ..................................................................................................... 3

USER INTERFACE .......................................................................................................... 4

NTERING VALUES

ISPLAY

RROW AND DECIMAL POINT

IAMETER’ AND ‘SETUP’ KEY

ATE’ KEY

UMPING RATE UNITS

OLUME’ KEY

EVERSE PURGE KEY

TART

‘S

ETUP’ KEY

PECIAL POWER-UP FUNCTIONS

IRMWARE VERSION DISPLAY

RROR AND STATUS MESSAGES

..................................................................................................................... 5

LEARING “VOLUME DISPENSED

HANGING VOLUME DISPENSED UNITS

’/’S

TOP’ KEY

ESET PUMPING PARAMETERS

......................................................................................................... 4

.................................................................................................................. 4

................................................................................................................ 6

..................................................................................................... 6

....................................................................................................... 6

................................................................................................................ 6

...................................................................................... 1

....................................................................................... 1

............................................................ 2

.................................................................................. 5

...................................................................................... 5

............................................................................................... 6

” ............................................................................ 6

.................................................................... 6

............................................................................... 7

.................................................................................. 7

................................................................................. 7

OPERATION ..................................................................................................................... 7

6.1 S

6.2 O

6.3 P

6.4 C

6.5 V

9.1 A

9.2 T

9.3 S

9.4 C

9.5 S

YRINGE INSIDE DIAMETER

6.1.1 V

SETUP CONFIGURATION ............................................................................................. 9

REAR OF PUMP ............................................................................................................... 9

APPENDIX ......................................................................................................................... 9

9.1.1 S

9.1.2 F

OLUME UNITS: DEFAULT AND HOW TO CHANGE

PERATING THE PUMP

URGING

HANGING THE PUMPING RATE WHILE PUMPING

OLUME DISPENSED

CCESSORIES

ROUBLESHOOTING AND MAINTENANCE

PECIFICATIONS

USTOM APPLICATIONS

YRINGE DIAMETERS AND RATE LIMITS

.......................................................................................................................... 8

....................................................................................................... 8

.................................................................................................................. 9

YRINGE HEATER

IRMWARE AND HARDWARE UPGRADE

...................................................................................................... 9

............................................................................................................ 10

........................................................................................... 7

.................................................. 7

................................................................................................... 8

...................................................... 8

.................................................................... 9

................................................................... 10

............................................................................................... 10

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New Era Pump Systems Inc.

General Information and Packing List

Thank you for purchasing the Model NE-300 “Just Infusion”™ Syringe Pump. With the NE-300 syringe pump you will be able to digitally set an infusion rate for continuous pumping.

Please familiarize yourself with the NE-300’s operation by reading this user's manual. For future reference, record the serial number, located on the rear of the pump, and the date of purchase.

New Era Pump Systems Inc., located in Farmingdale, NY USA, can be contacted at:

Phone: (631) 249-1392 FAX: (707) 248-2089 Email: INFO@SYRINGEPUMP.COM

This Operating Manual, and the NE-300’s hardware, electronics and firmware are copyrighted.

www.SyringePump.com

WWW.SYRINGEPUMP.COM

Model NE-300 Syringe Pump

Packing List

Included with the NE-300 Syringe Pump are the following items:

• One of the following external unregulated power supply adapters:

Input: One of: 120V AC 60 Hz, 220V AC 50 Hz, 240V AC 50 HZ Output: 12V DC @ 800 mA (or compatible regulated power supply)

• This Operating Manual

1.1

Warnings! and Cautions

Read the user’s manual

No user serviceable parts are inside.

Disconnect power from the pump when connecting or disconnecting cables.

Do not immerse the pump in liquid

Install on a stable surface.

Keep hands and loose clothing away from the pump's moving parts.

The pump can automatically start when the Pumping Parameters is operating or when attached to an external control device.

Prevent liquids from entering openings in the rear of the pump.

Use only with the supplied power supply connected to a power source as specified on the power supply label.

Do not push objects of any kind into the chassis openings, except for appropriate cables and connectors.

If the pump becomes damaged, do not use unless certified safe by a qualified technician. Damage includes, but is not excluded to, frayed cords and deterioration in performance.

Discharge static from control cables before

connecting by touching the cable to ground.

Before touching the pump, discharge static by

touching ground.

1.2

Disclaimer and Warranty

Disclaimer

New Era Pump Systems Inc. makes no representations or warranties, expressed, statutory or implied, regarding the fitness or merchantability of this product for any particular purpose. Further, New Era Pump Systems Inc. is not liable for any damages, including but not limited to, lost profits, lost savings, or other incidental or consequential damages arising from ownership or use of this product, or for any delay in the performance of its obligations under the warranty due to causes beyond its control. New Era Pump Systems Inc. also reserves the right to make any improvements or modifications to the product described in this manual at any time, without notice of these changes. New Era Pump Systems Inc. products are not designed, intended, or authorized for use in applications or as system components intended to support or sustain human life, as a clinical medical device for humans, or for any application in which the failure of the product could create a situation where personal injury or death may occur.

All brand and product names used in this manual are the trademarks of their respective owners.

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New Era Pump Systems Inc.

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Model NE-300 Syringe Pump

Warranty

New Era Pump Systems Inc. warranties this product and accessories for a period of two year, parts and labor, from the date of purchase. The repaired unit will be covered for the period of the remainder of the original warranty or 90 days, whichever is greater.

A return authorization number must be obtained from New Era Pump Systems Inc. before returning a unit for repair. Warranty covered repairs will not be performed without a return authorization number. At the option of New Era Pump Systems Inc., a defective unit will be either repaired or replaced.

This warranty does not cover damage by any cause including, but not limited to, any malfunction, defect or failure caused by or resulting from unauthorized service or parts, improper maintenance, operation contrary to furnished instructions, shipping or transit accidents, modifications or repair by the user, harsh environments, misuse, neglect, abuse, accident, incorrect line voltage, fire, flood, other natural disasters, or normal wear and tear. Changes or modifications not approved by New Era Pump Systems Inc. could void the warranty. Wearable parts, such as drive nuts, are not covered by the warranty.

The foregoing is in lieu of all other expressed warranties and New Era Pump Systems Inc. does not assume or authorize any party to assume for it any other obligation or liability.

Overview

The NE-300 is a general purpose single syringe pump capable of infusing at digitally set pumping rates. It is controlled from a microcontroller based system which drives a step motor, allowing a wide range of pumping rates configured to the inside diameter of the loaded syringe. The syringe is driven from a drive-screw and drive-nut mechanism.

Features:

♦ Infusion pumping of syringes up to 140 mL. ♦ Pumping rates from 0.73 µL/hr with a 1 mL to

1500 mL/hr with a 60 mL.

♦ Display of infused volume.

♦ Non-volatile memory of all operating parameters. ♦ Power Failure Mode: Re-starts pumping after a

power interruption.

2.1

Glossary of Terminology and Concepts

When a device has as many features as the NE-1000 series, understanding its operation could be a daunting task at first. By understanding the key concepts and terminology used in this manual, the operation of the NE-300 will become quite intuitive. Every effort has been made to design the NE-300 with a consistent and intuitive user interface.

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New Era Pump Systems Inc.

Momentary Press:

Display Blink:

Plunger

Barrel

Barrel Flange

To facilitate and enhance your understanding of the NE-300’s operation, please take the time to familiarize yourself with the basic concepts below:

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Model NE-300 Syringe Pump

Parts of the Pump

1) Pusher Block

2) End Plate

3) Power On/Off Switch

4) Drive-Nut Button

5) Drive-Screw

6) Syringe Holder Block

7) ‘V’ Slot (on Syringe Holder Block)

8) Syringe Clamp

9) Keypad / User Interface

10) Guide Rod (2 guide rods)

Parts of a Syringe

Flange

Plunger

Terminology

Setup

♦ Place the pump on a stable surface.

♦ Plug the round connector end of the supplied power supply adapter into the power plug located on the

lower right of the pump's rear. See section 8, Rear of Pump, for a diagram of the rear of the pump. Plug the other end of the power supply adapter into an appropriate electrical outlet. The pump will be powered when the bottom of the power switch, located on the upper right of the rear of the pump, labeled ‘1’, is pressed. The red indicator on the switch is visible when the power switch is in the ‘on’ position. After power is applied to the pump, the pump’s display will flash.

♦ Next, the Pumping Parameters can be entered. Before the pump can be started, the pump needs the

measurement of the inside diameter, in millimeters (mm), of the syringe that will be loaded. The syringe diameter is entered using the keypad on the front panel of the pump.

♦ Finally, the syringe can be loaded and the pump started.

Loading Syringes

The syringe is loaded by securing the barrel and the pusher flange as follows:

1: Press in fully the white drive-nut button on the pusher block, releasing the block. Taking care not to

drag the drive-nut on the drive-screw, slide the block away from the syringe holder, providing sufficient space for the loaded syringe. Then release the white button.

A quick press, less than 1 second, and then release of a key on the keypad.

A momentary blanking of the LCD display. This indicates that the new data entered by the user is valid and has taken effect.

2: Lift the syringe clamp above the syringe holder block. Turn it 1/4 turn and then lower it onto the

3: Load the syringe with the barrel over the syringe holder and the syringe plunger towards the middle of

4: Lift the syringe clamp to slightly above the height of the syringe barrel and then turn the syringe clamp 1/4

5: Press the white drive-nut button to slide the pusher block against the syringe plunger. Release the white

⇒ To unload the syringe, reverse the instructions for syringe loading.

syringe holder block. The syringe clamp should be out of the ‘V’ slot.

the pump. Place the barrel on the syringe holder, in the ‘V’ slot, with the barrel flange to the left of the syringe holder block.

turn back to its original position and lower it onto the syringe barrel.

drive-nut button.

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New Era Pump Systems Inc.

Dispensed

Phase #

Function

Volume Dispensed

Indicator

User Interface

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Units Indicators

Model NE-300 Syringe Pump

Reverse Purge Indicator

Motor Operating

Volume

min hr

Volume

Withdraw

Diameter

Setup

Pumping

Start

Stop

Reverse Purge Key

Decimal Point: Press 2 keys

Figure 1: Front Panel

5.1

Entering Values

Syringe ID

mm mL

Rate

Pumping Program

Unused Functions

When applicable, values can be changed by displaying the current value, then using the arrow keys. The new value will be stored in the pump’s non-volatile memory, meaning that the new value will not be lost the next time that power is applied to the pump.

A displayed value can be changed by pressing the up-arrow keys below each digit. To set or clear the decimal point, press the 2 up-arrow keys below the 2 digits next to the decimal point position. If the value to be changed is not currently displayed, when applicable, press the key associated with the required value. The display will show the setting’s current value and its units, if any.

While the current value is being changed, the units LEDs associated with the value, if any, will blink. Except where noted, the new value is stored, and/or the selected operation takes effect, when either

1) A non-arrow key is pressed or

2) After a 2 second delay since the last arrow key was pressed.

If the new value is valid and different from the original value, the display will blink, indicating that the new value was stored. Otherwise, if the value was invalid, an error message will be displayed. Pressing any key clears the error message and restores the original value.

In general, if a parameter has 2 values, ‘off’ and ‘on’, they are represented by the numbers ‘0’ and ‘1’, respectfully.

5.2

LCD Display

The display consists of a 4 digit reflective LCD display. This is the general purpose user display device for displaying floating point values, functions and parameters. The colon (:) is used for separating function abbreviations from their parameter values.

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New Era Pump Systems Inc.

Pumping rate units are expressed using 2 LEDs:

min

µL

min

µL

min

µL

min

µL

5.3

LEDs

To the right of the LCD are 8 red, round, LED indicators. The first 2 columns display the units of the displayed values. Units are expressed using 1 or 2 LEDs. For instance, ‘mL / hr’ is expressed by lighting the ‘mL’ and the ‘hr’ LEDs.

LED Description

mm Millimeters

mL Milliliters

min Minutes

hr Hours

Withdraw Pumping Direction:

Dispensed Displayed volume is dispensed volume

Pumping Lit: Motor is operating

5.4

Each of the four digits in the display is associated with the up arrow key directly below it. When applicable, the arrow key is used to increment the value of that digit, or advance to the next setting.

Microliters

Lit: Withdraw Purge Pumping

Not lit: The Pump is stopped

Up Arrow and Decimal Point

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Model NE-300 Syringe Pump

‘mL/min’ =

‘mL/hr’ =

‘µL/min’ =

‘µL/hr’ =

Each press of an up arrow key will increase the digit by 1, up to 9, and then back to 0. The arrow keys may also be held down for continuous incrementing of numbers. Some parameters have a fixed range of values, such as some setup parameters that are either turned on or off. In these cases, the arrow key will only scroll up to the maximum value for that parameter, then back to the minimum value.

When changing a value’s units, each press of any arrow key will change the unit’s LEDs to the next unit selection.

When the display blinks, the new value is stored and takes effect. This will occur when a non-arrow key is pressed or after a 2 second delay since the last key press.

Decimal Point

There are 4 decimal point positions on the LCD display. Each decimal point position is to the right of a digit in the display. The last decimal point position, to the right of the right-most digit is not displayed, indicating whole numbers with no decimal point.

To set or clear the decimal point position, simultaneously press the 2 up-arrow keys under the 2 digits next to the decimal point position.

Alternatively, use the left-most up-arrow key / decimal point key (/). Press and hold this key for at least 1 second and wait until the left-most digit scrolls from ‘9’ to ‘0’. While continuing to hold this key, the decimal point will shift 1 position to the right. After the right-most decimal point position, the decimal point will shift to the first decimal point position. Release the key when the decimal point is in the required position.

5.5

‘Diameter’ and ‘Setup’ Key

The ‘Diameter’ key allows the syringe inside diameter to be viewed and set. While displaying the diameter, the ‘mm’ LED is lit. When pump is stopped, pressing the arrow keys will change the current diameter (see sec. 5.4, Up Arrow and Decimal Point). The ‘mm’ LED will blink while the diameter is being changed.

If the ‘Diameter’ key is pressed and held, ‘Setup’ mode will be entered. (see sec. 5.10, ‘Setup’ ).

5.6

‘Rate’ Key

The ‘Rate’ key allows the pumping rate to be viewed or changed while pumping or stopped. While the pump is stopped, momentary presses of this key will switch between the ‘Rate’ display and the select rate units mode.

To change the pumping rate displayed, while pumping or stopped, use the up arrow keys (see sec. 5.4, Up Arrow and Decimal Point). The rate units will blink while the rate is being changed. The new pumping rate

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New Era Pump Systems Inc.

is entered and takes effect immediately when the display blinks after a 2 second delay or when a non-arrow key is pressed. The new pumping rate is stored in memory.

See section 9.5, “Syringe Diameters and Rate Limits”, for a list of minimum and maximum pumping rates. A pumping rate of 0.0 will stop the pump. When the pumping rate is changed, if it is out of range of the pumping

rate limits, the display will show . Pressing any key clears the message and returns to the previous pumping rate.

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Model NE-300 Syringe Pump

5.6.1 Pumping Rate Units

The pumping rate units can only be changed when the Pump is stopped. A momentary press of the ‘Rate’ key will enter Rate Units Change mode. The 2 LEDs representing the units will blink and the display will show:

Each press of any up arrow key selects the next rate units, as indicated by the blinking units LEDs. When the required rate units are blinking, press any non-arrow key or wait 2 seconds. The display will blink, indicating the rate units are stored in memory.

5.7

‘Volume’ Key

Pressing this key will display the “Volume Dispensed”, as indicted by the ‘Dispensed’ LED. The units of the volume are set according to the syringe diameter, but can be changed.

5.7.1 Clearing “Volume Dispensed”

With the pump stopped and displaying the “Volume Dispensed”, pressing and holding any up-arrow key for one second will reset the dispensed volume to 0.000.

5.7.2 Changing Volume Dispensed Units

With the “Volume Dispensed” 0.000 displayed, press any up-arrow key to enter “Set Volume Units” mode.

The display will show: and the Volume units will blink. Press an up-arrow key to toggle the volume units between ‘mL’ and ‘µL’ while the units are blinking.

5.8

Reverse Purge Key

The direction key, ‘ ’, is used to un-jam the pusher block after an over infusion, making it difficult to release the nut block. Press and hold this button for at least 1 second to reverse purge the pump until the pusher block is released. Release this key to stop the pump. While this key is held, the display will show:

. The Withdraw and Pumping LED’s will be lit during the reverse purge.

5.9

‘Start’/’Stop’ Key

The ‘Start/Stop’ key starts or stops the Pump’s operation. Pressing this key switches between Pumping and the Pump stopped. The ‘Pumping’ LED will indicate that the Pump is pumping.

Pressing and holding this key while starting the Pump will start Purge Mode. Purge will begin after the key is held for one second, and continues until the key is released. The pump stops after the key is released.

5.10

The secondary function of the ‘Diameter’ key is ‘Setup’. While the Pump is stopped, press and hold the

‘Diameter’ key until the setup configuration parameter, “Power Failure Mode”, is displayed:

The display will consecutively display, for about 2 seconds, each Setup Configuration parameter and its current setting. Pressing any non-arrow key will immediately advance to the next Setup Configuration parameter, if any.

‘Setup’ Key

To change a Setup Configuration parameter, press an arrow key under the parameter’s value. To store the new value, press any non-arrow key or wait 2 seconds. If the parameter value differs from its previous value, the display will blink. The new parameter value will be stored and the next parameter will be displayed, if any. See section 7, Setup Configuration for a complete description of the Setup Configurations.

After the last configuration parameter is displayed, the display reverts back to displaying the syringe diameter. Any new parameter value will take effect immediately upon being stored.

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New Era Pump Systems Inc.

www.SyringePump.com

Model NE-300 Syringe Pump

5.11

The following special functions are accessed by pressing the relevant key, while turning on power to the pump.

Special Power-Up Functions

5.11.1 Firmware Version Display

To display the pump’s firmware version, press the left-most up arrow key (/) while turning on power to

the pump. The display will show:

, or similar. Pressing any key will clear the display.

5.11.2 Reset Pumping Parameters

To clear out the current Pump setups, press the right-most up arrow key () while turning on power to the

pump. The display will show . Pressing any key will clear the display.

With pumps having as many complex features as the NE-1000 series, it is easy for a novice user experimenting with the pump's setup to get the pump into a 'weird' state. Performing this reset function will bring the pump out of a 'weird' state.

5.12

Error and Status Messages

Value entered is ‘Out Of Range’ of the pump’s operational limits. Check the pumping rate and/or the syringe inside diameter setting is correct.

Indicates pumping rate or volume units change mode. The units LED's will also be blinking. Press any up arrow key to change the units.

Key pressed is not currently applicable.

Indicates that the pump is purging. Displayed while holding down the 'Start/Stop' key.

Displayed while holding down the direction key and performing a reverse purge.

Operation

Before the pump can be operated, the pumping data must be setup. The syringe inside diameter and a non-zero pumping rate needs to be set. The operation of the pump can then be started by pressing the ‘Start / Stop’ key.

6.1

Syringe Inside Diameter

The syringe inside diameter can only be set while the Pump is stopped. Use the up arrow keys to set the diameter value. While the diameter value is being set, the ‘mm’ LED will blink. The new diameter value is stored after pressing any non-arrow key, or after a 2 second delay.

Valid syringe diameters are from 0.1 mm to 50.0 mm. If the diameter is out of this range, the display will show ‘oor’. Pressing any key restores the diameter display to its previous value. Changing the syringe diameter will not zero the pumping rate. Section 9.5, “Syringe Diameters and Rate Limits”, is a representative list, for reference, of syringe diameters for various syringe manufacturers and syringe sizes.

6.1.1 Volume Units: Default and How to Change

The units of the accumulated infusion volume is set according to the syringe diameter setting. If the default volume units are changed (see next section), the selected volume units will remain in effect until a reset function is performed.

From 0.1 to 14.0 mm Syringes smaller than 10 mL: Volume units are ‘µL’ From 14.01 to 50.0 mm Syringes greater than or equal to 10 mL: Volume units are ‘mL’

Changing Volume Units

The volume units used for the accumulated volume can be changed to either ‘mL’ or ‘µL’. Volume units can only be changed when the pump is stopped.

Display the “Volume Dispensed” by pressing the “Volume” key. The current volume units and the “Dispensed” LED will be lit.

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New Era Pump Systems Inc.

Set the Volume Dispensed to 0.000 if it is not zero: Press and hold any up arrow key until the Volume Dispensed is set to 0.000.

Then, pressing any up-arrow key will change the display to and the current volume units will blink.

Now press any up-arrow key to switch the volume units between ‘mL’ and ‘µL’. Press any non-arrow key or wait 2 seconds to enter the new volume units. The display will blink when entered. The selected volume units will remain in effect and override the default volume units. Changing the diameter will no longer change the volume units. Performming a system reset will cancel the override and allow the volume units to change to the default volume units when setting the syringe diameter.

6.2

Operating the Pump

When the “Start/Stop” key is pressed, the Pump will begin pumping, and the ‘Pumping’ LED will be lit. The pump will pump continuously at the set pumping rate until stopped.

Either the pumping rate, “Volume Dispensed”, or syringe diameter can be displayed while pumping. Press the relevant key to change the display. While displaying the pumping rate, press the up arrow keys to change the pumping rate.

Warning: The NE-300 does not have stall detection. The pump must be stopped manually when the syringe is empty or the motor force is exceeded. The white drive nut block can be damaged when the pump is operating while the motor cannot turn. This will violate the warranty and replacement of the drive nut block will not be covered.

6.3

Purging

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Model NE-300 Syringe Pump

To purge the syringe, with the Pump stopped, press and hold the 'Start/Stop' key. The Pump will start pumping, then, after one second, purge will begin. The pump will pump at its top speed. Purging will continue until the 'Start/Stop' key is released, and then the pump will stop. While purging the display will

show: .

Press and hold the direction button, to perfrom a reverse purge. The display will show:

6.4

Changing the Pumping Rate While Pumping

The pumping rate can be changed while the pump is operating. To change the pumping rate, display the current pumping rate by pressing the ‘Rate’ key, if needed. With the pumping rate displayed, press the up arrow keys to change the rate. The rate units will blink while the rate is being changed. Rate units cannot be changed while pumping.

The new rate is stored after a 2 second delay or by pressing a non-arrow key. If the new rate is within the operating range of the pump, the display will blink and the new rate will be stored in memory and the pump will begin pumping at the new rate. If the new rate is out of the operating range of the pump, the display will

show . Pressing any key clears the message and restores the previous rate.

6.5

Volume Dispensed

The accumulated Volume Dispensed can be displayed at any time by pressing the Volume key. The display will show the total accumulated volume pumped with the ‘mL’ or ‘µL’ LED lit and the ‘Dispensed’ LED lit. Volume is computed based upon the syringe inside diameter setting.

The “Volume Dispensed” accumulation is reset to 0 when:

A) With the pump stopped, pressing and holding any up arrow key while displaying the volume. B) The syringe diameter is changed. C) The accumulated Volume Dispensed rolls over from 9999 to 0. D) The pump is powered on.

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New Era Pump Systems Inc.

NE-300

Setup Configuration

To change or view the setup configuration, the Pump must be stopped. Press and hold the ‘Diameter’/‘Setup’ key until the parameter, ‘PF’ is displayed. After 2 seconds, or when any non-arrow key is pressed, the next parameter will be displayed. (See sec. 5.10, ‘Setup’ Key). Pressing an arrow key under a value will change the parameter. The following will be displayed:

Power Failure Mode. Where ‘n’ is the current setting: ‘0’ = Disabled, ‘1’ = Enabled.

When enabled, if the Pump was pumping when power to the pump was disrupted, the Pump will automatically start pumping when power is reconnected to the pump. The accumulated volume will be reset to 0. Pressing any key on the keypad while powering up the pump will stop the Pump from starting in Power Failure Mode.

Low Noise Mode, Where ‘n’ is the current setting: ‘0’ = Disabled, ‘1’ = Enabled.

A side effect of the NE-300’s high precision micro-stepped motor driver is a high frequency resonance sound at very low pumping speeds. This mode minimizes this sound by reducing the micro-stepping, increasing pulsations.

Rear of Pump

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Model NE-300 Syringe Pump

NEW ERA PUMP SYSTEM S, Inc.

WWW.SYRINGEPUM P.COM

(631) 249-1392

Figure 2: Rear of Pump

Appendix

9.1

Accessories

Farmingdale, NY info@syringepump.com

9.1.1 Syringe Heater

See www.SyringeHeater.com for details.

Flexible heating pads that wraps around the syringe. Thermo-Kinetic Heat Clamping controller will heat a syringe to a set temperature up to 100 C.

9.1.2 Firmware and Hardware Upgrade

Contact your dealer about upgrading your pump with other features from the NE-1000 Programmable Syringe Pump Series. See www.SyringePump.com

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New Era Pump Systems Inc.

9.2

Troubleshooting and Maintenance

Maintenance: Periodically, a small amount of all-purpose oil should be applied to the guide rods.

The mechanism should be kept clean to prevent impeded operation.

No other special maintenance or calibrations are needed

Pusher block makes a snap or click sound when the pump is started: This is a normal condition. When the pusher block is manually moved, the drive-nut may not have been fully engaged on the drive screw. The sound heard is the drive-nut engaging on the drive screw.

9.3

Specifications

www.SyringePump.com

Model NE-300 Syringe Pump

Mechanical & Electrical

Syringe sizes: Up to 60 mL. 140 mL partially filled. Number of syringes: 1 Motor type: Step motor Motor steps per revolution: 400 Micro-stepping: 1/8 to 1/2 depending on motor speed Advance per step: 0.2126 µm to 0.8504 µm depending on motor speed Motor to drive screw ratio: 15/28 Drive screw pitch: 20 revolutions/” Power connector: 2.1 mm, center positive, DC Voltage at power connector: 12V DC at full load Amperage: 750 mA at full load Power supply type: External wall adapter, country and power source specific Power supply output rating: 12V DC @ 800 mA (or greater if regulated power supply) Dimensions: 8 3/4” x 5 3/4” x 4 1/2” (L x W x H)

(22.86 cm x 14.605 cm x 11.43 cm)

Weight: 3.6 lbs. (1.63 kg)

Operational

Accuracy Within +/- 1% over length of syringe,

exclusive of syringe variations.

Reproducibility +/- 0.1%

Maximum speed: 3.7742 cm/min Minimum speed: 0.004205 cm/hr Maximum pumping rate: 1257 mL/hr with a B-D 60 mL syringe Minimum pumping rate: 0.73 µL /hr with a B-D 1 mL syringe Maximum force: 35 lbs. at minimum speed, 18 lbs. at maximum speed Syringe inside diameter range: 0.100 to 50.00 mm

9.4

Custom Applications

For specialized and OEM applications, contact your dealer or New Era Pump Systems Inc. Custom modifications can be made to the mechanics or the firmware.

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New Era Pump Systems Inc.

Syringe

Inside

Maximum

Minimum

Maximum

4.699

8.585

11.99

14.43

19.05

21.59

26.59

4.69

9.65

12.45

15.9

20.05

22.9

29.2

5.74

8.941

12.7

15.72

20.12

23.52

26.64

140

4.7

8.95

15.8

20.15

23.1

29.7

6.7

8.91

9.06

11.75

14.67

19.62

22.69

26.96

9.538

12.7

9.538

19.13

28.6

Syringe

Diameter

Maximum

Minimum

Syringe

Diameter

Maximum

Minimum

0.343

2.303

0.176

0.485

0.351

0.728

4.606

0.701

1.03

7.284

1.752

100

1.457

10.3

3.504

0.5

0.103

14.57

7.01

0.146

23.03

17.52

0.206

27.5

24.98

0.326

34.99

40.43

9.5

Syringe Diameters and Rate Limits

www.SyringePump.com

Model NE-300 Syringe Pump

Manufacturer

(all names ™)

B-D

HSW Norm-Ject

Monoject

Terumo

Poulten & Graf (Glass)

Steel Syringes

SGE (gas tight)

Hamilton Microliter

(mL)

(µL)

Diameter

Inside

(mm)

Rate

(mL/hr)

39.27

255.6 4.748

370.3 6.876

645.4 11.99

1257 23.35

39.11 0.727

165.6 3.076

275.6 5.119

449.6 8.349

714.9 13.28

932.6 17.32 1516 28.16

58.59 1.088

142.1

286.8 5.326

439.4 8.161

719.9 13.37

983.8 18.27 1262 23.44 2568 47.69

39.28

142.4 2.646

300.5 5.581

443.9 8.244

722.1 13.41

1568 29.13

79.83 1.483

141.1 2.622

145.9 2.711

245.5 4.559

382.7 7.107

684.6 12.72

915.6 17.01 1292 24.01

161.7 3.005

286.8 5.326

161.7 3.005

650.8 12.09 1454 27.01

Rate

(µL/hr)

209.2

418.3

942.5 1886 3775

18.86

37.91

75.47

(µL/hr)

131 2.434

829

949 17.63

(µL/hr)

189

Rate

0.73

15.4

2.64

0.73

Rate

0.004

0.008

0.018

0.036

0.071

0.001

0.002

0.004

Rate

(mL/min)

0.654

2.184

4.261

6.172

10.75

13.81

20.95

0.651

2.76

4.594

7.493

11.91

15.54

25.27

0.976

2.369

4.78

7.324

11.99

16.39

21.03

42.8

0.654

2.374

5.009

7.399

12.03

15.81

26.14

1.33

2.353

2.433

4.092

6.379

11.41

15.26

21.54

2.696

4.78

2.696

10.84

24.24

(mL)

0.25

0.5

2.5

100

Inside

(mm)

3.2

Rate

(mL/hr)

9.432

18.86

37.73

94.36

188.6

377.5

943.2

1344 2177

Rate

(µL/hr)

Publication #1200-01 11 08/27/14