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USB-625x
User Manual
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National Instruments USB-625x, USB-622x, USB-628x User Manual

USER GUIDE
NI USB-622x/625x/628x OEM
M Series USB-6221/6225/6229/6251/6255/6259/6281/6289 OEM Devices
This document provides dimensions, pinouts, and information about the connectors, switch, LEDs, and chassis ground of the National Instruments USB-6221 OEM, USB-6225 OEM, USB-6229 OEM, USB-6251 OEM, USB-6255 OEM, USB-6259 OEM, USB-6281 OEM, and USB-6289 OEM devices. It also explains how to modify the USB device name in Microsoft Windows.
Caution There are no product safety, electromagnetic compatibility (EMC), or
CE marking compliance claims made for the USB-622x/625x/628x OEM devices. Conformity to any and all compliance requirements rests with the end product supplier.
Caution (USB-628x Devices) Exercise caution when placing USB-628x OEM devices inside
an enclosure. Auxiliary cooling may be necessary to keep the device under the maximum ambient temperature rating of 45 °C, as specified in the NI 628x Specifications.
Figure 1 shows the USB-6221/6251/6281 OEM and USB-6225/6229/6255/6259/6289 OEM devices.
USB-6221/6251/6281 USB-6225/6229/6255/6259/6289

Figure 1. USB-622x/625x/628x OEM Devices

Dimensions

Refer to the NI 622x Specifications document for USB-6221/6225/6229 specifications, the NI 625x Specifications document for USB-6251/6255/6259 specifications, and the NI 628x Specifications document for USB-6281/6289 specifications. Refer to the M Series User Manual for more information about USB-622x/625x/628x devices. You can find all documentation at
Figure 2 shows the dimensions of the USB-6221/6251/6281 OEM device.
ni.com/manuals.
NI USB-622x/625x/628x OEM User Guide 2 ni.com
6.950 (176.53)
4x 6.718 (170.63)
6.270 (159.26)
6.140 (155.96)
5.930 (150.62)
0.396 (10.06)
0.304 (7.72)
0.256 (6.50)
0.116 (2.95)
0.000 (0.00)
0.000 (0.00)
0.200 (5.08)
0.918 (23.32)
0.390 (9.91)
3.180 (80.77)
3.730 (94.74)
3.220 (81.79)
3.198 (81.22)
3.734 (94.84)
5.210 (132.33)
6.400 (162.56)
6.013 (152.74)
5.900 (149.86)
4X Ø 0.110 (2.79)
7X Ø 0.125 (3.18)
6.140 (155.96)
5.290 (134.37)
0.304 (7.72)
0.200 (5.08)
0.436 (11.07)
0.392 (9.96)
0.362 (9.19)
0.162 (4.11)
0.062 (1.57)
0.000 (0.00)
0.200 (5.08)
0.393 (9.98)
1.057 (26.85)
0.000 (0.00)
2.072 (52.63)
1.750 (44.45)
2.300 (58.42)
3.296 (83.72)
2.606 (66.19)
3.080 (78.23)
2X Ø 0.140 Cutout
in Panel for LEDs
Ø 0.330 Cutout in Panel
for Power Connector
6.200 (157.48)
0.609 (15.47)
0.515 (13.08)
0.442 (11.23)
6.400 (162.56)

Figure 2. USB-6221/6251/6281 OEM Dimensions in Inches (Millimeters)

© National Instruments Corporation 3 NI USB-622x/625x/628x OEM User Guide
Figure 3 shows the dimensions of the USB-6225/6229/6255/6259/6289 OEM device.
6.950 (176.53)
4x 6.718 (170.63)
6.270 (159.26)
6.140 (155.96)
5.930 (150.62)
5.839 (148.31)
5.499 (139.67)
0.396 (10.06)
0.304 (7.72)
0.256 (6.50)
0.116 (2.95)
0.000 (0.00)
0.000 (0.00)
0.200 (5.08)
0.918 (23.32)
0.390 (9.91)
0.200 (5.08)
3.180 (80.77)
3.198 (81.22)
2.072 (52.63)
3.296 (83.72)
3.734 (94.84)
3.730 (94.74)
3.220 (81.79)
6.400 (162.56)
6.013 (152.74)
5.900 (149.86)
5.210 (132.33)
6.200 (157.48)
4X Ø 0.110 (2.79)
7X Ø 0.125 (3.18)
6.140 (155.96)
5.290 (134.37)
0.304 (7.72)
0.200 (5.08)
0.436 (11.07)
0.392 (9.96)
0.362 (9.19)
0.162 (4.11)
0.062 (1.57)
0.000 (0.00)
0.393 (9.98)
1.057 (26.85)
0.000 (0.00)
1.750 (44.45)
2.300 (58.42)
2.606 (66.19)
3.080 (78.23)
2X Ø 0.140 Cutout
in Panel for LEDs
Ø 0.330 Cutout in Panel
for Power Connector
0.609 (15.47)
0.515 (13.08)
0.442 (11.23)
6.400 (162.56)

Figure 3. USB-6225/6229/6255/6259/6289 OEM Dimensions in Inches (Millimeters)

NI USB-622x/625x/628x OEM User Guide 4 ni.com

I/O Connector Pinouts

Figures 4 through 9 show the connector pinouts for the USB-6221 OEM, USB-6225 OEM, USB-6229 OEM, USB-6251 OEM, USB-6255 OEM, USB-6259 OEM, USB-6281 OEM, and USB-6289 OEM devices.
Refer to the M Series User Manual at information about USB-622x/625x/628x signals and how to connect them.
ni.com/manuals for more
© National Instruments Corporation 5 NI USB-622x/625x/628x OEM User Guide
Bank 0
50-Pin Digital Connector
Bank 0
+5 V
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
49
50
47
48
45
46
43
44
41
42
39
40
37
38
35
36
33
34
31
32
29
30
27
28
25
26
23
24
21
22
19
20
17
18
15
16
13
14
11
12
10
8
6
4
2
Bank 0
+5 V
PFI 15
PFI 14
PFI 13
PFI 12
PFI 11
PFI 10
PFI 9
PFI 8
PFI 7
PFI 6
PFI 5
PFI 4
PFI 3
PFI 2
PFI 1
PFI 0
P0.7
P0.6
P0.5
9
P0.4
7
P0.3
5
P0.2
3
P0.1
1
P0.0
34-Pin Analog Connector
Bank 0
AI GND
AI 7
AI 14
AI GND
AI 5
AI 12
AI GND
AI 3
AI 10
AI GND
AI 1
AI 8
AI GND
AI GND
AI GND
AO 1
AO 0
34
33
AI 15
32
31
AI GND
30
29
AI 6
28
27
AI 13
26
25
AI GND
24
22
20
18
16
14
12
10
AI 4
23
21
AI 11
19
AI GND
17
AI 2
AI 9
15
AI GND
13
11
AI 0
9
AI SENSE
8
7
NC
6
AO GND
5
4
3
AO GND
2
1
AO GND
NC = No Connect

Figure 4. USB-6221 OEM Connector Pinout

NI USB-622x/625x/628x OEM User Guide 6 ni.com
50-Pin Analog/Digital Connectors
Bank 1
Bank 0
+5 V
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
D GND
Bank 1
49
50
47
48
45
46
43
44
41
42
39
40
37
38
35
36
33
34
31
32
29
30
27
28
25
26
23
24
21
22
19
20
17
18
15
16
13
14
11
12
10
8
5
6
3
4
1
2
Bank 0
+5 V
PFI 15
PFI 14
PFI 13
PFI 12
PFI 11
PFI 10
PFI 9
PFI 8
PFI 7
PFI 6
PFI 5
PFI 4
PFI 3
PFI 2
PFI 1
PFI 0
P0.7
P0.6
P0.5
9
P0.4
7
P0.3
P0.2
P0.1
P0.0
AI 71
AI 78
AI GND
AI 77
AI 68
AI 67
AI 74
AI GND
AI 73
AI 64
AI 55
AI 62
AI GND
AI 61
AI 52
AI 51
AI 58
AI GND
AI 57
AI 48
AI 39
AI 46
AI GND
AI 45
AI 44
50
48
46
44
42
40
38
36
34
32
30
28
26
24
22
20
18
16
14
12
10
AI 79
49
AI 70
47
AI 69
45
AI 76
43
AI GND
41
AI 75
39
AI 66
37
AI 65
35
AI 72
33
AI GND
31
AI 63
29
AI 54
27
AI 53
25
AI 60
23
AI GND
21
AI 59
19
AI 50
17
AI 49
15
AI 56
13
AI GND
11
AI 47
9
AI 38
8
7
AI 37
6
5
AI GND
4
3
AI 36
2
1
Bank 0
34
33
32
31
30
29
28
27
26
25
24
23
22
21
20
19
18
17
16
15
14
13
12
11
10
8
6
4
2
9
7
5
3
1
AI 35
AI 34
AI 41
AI GND
AI 40
AI 23
AI 22
AI 29
AI GND
AI 20
AI 27
AI GND
AI 18
AI 25
AI GND
AI 16
AI SENSE 2
34-Pin Analog Connectors
Bank 1
Bank 0
AI GND
AI 7
AI 14
AI GND
AI 5
AI 12
AI GND
AI 3
AI 10
AI GND
AI 1
AI 8
AI GND
AI GND
AI GND
AO 1
AO 0
Bank 1
34
33
32
31
30
29
28
27
26
25
24
23
22
21
20
19
18
17
16
15
14
13
12
11
10
8
6
4
2
9
7
5
3
1
AI 15
AI GND
AI 6
AI 13
AI GND
AI 4
AI 11
AI GND
AI 2
AI 9
AI GND
AI 0
AI SENSE
NC
AO GND
AO GND
AO GND
AI 43
AI GND
AI 42
AI 33
AI 32
AI 31
AI GND
AI 30
AI 21
AI 28
AI GND
AI 19
AI 26
AI GND
AI 17
AI 24
AI GND
NC = No Connect

Figure 5. USB-6225 OEM Connector Pinout

© National Instruments Corporation 7 NI USB-622x/625x/628x OEM User Guide
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