Multichannel Systems MEA1060 User Manual

Technical Specifications Date of Print: 26.01.2007

MEA1060 Amplifiers

MEA1060-Inv-Standard MEA1060-Up-Standard MEA1060-Inv-BC-Standard (incl. FA60S-BC) MEA1060-Up-BC-Standard (incl. FA60S-BC) MEA96-Well-Standard

Operating temperature 10 °C to 50 °C 10 °C to 50 °C 10 °C to 50 °C 10 °C to 50 °C 10 °C to 50 °C Storage temperature 0 °C to 50 °C 0 °C to 50 °C 0 °C to 50 °C 0 °C to 50 °C 0 °C to 50 °C Relative humidity 10 % to 85 % Dimensions (W x D x H) 165 mm x 165 mm x 20 mm (29 mm with

Weight 800 g 600 g 750 g (without FA60S) + 450 g (FA60S) 750 g (without FA60S) + 450 g (FA60S)

Supply voltage ± 6 VDC to ± 9 VDC ± 6 VDC to ± 9 VDC ± 6.5 VDC to ± 9 VDC ± 6.5 VDC to ± 9 VDC ± 6.5 VDC to ± 9 VDC Supply current max. 220 mA, typically ± 150 mA max. 220 mA, typically ± 150 mA ± 550 mA ± 550 mA max. 220 mA, typically ± 150 mA

Number of stimulus input channels 60 60 2 2 0 Maximum stimulus input voltage n/a n/a ± 5 V ± 5 V n/a

Number of input channels 60 60 60 60 96 Input voltage ± 4 mV (with respect to the standard gain of

Input impedance Input noise < 800 nV Noise density en = 15 en = 15 en = 15 en = 15 en = 15

Number of output channels 60 60 60 60 96 Output voltage ± 5 V ± 5 V ± 5 V ± 5 V ± 5 V Output current 10 mA 10 mA 10 mA 10 mA 10 mA Output impedance Bandwidth* 1 Hz to 3 kHz (standard), 1 Hz to 10 kHz

Filter slope

sockets)

1200)

Ω parallel to 10 pF 1011 Ω parallel to 10 pF 1011 Ω parallel to 10 pF 1011 Ω parallel to 10 pF 1011 Ω parallel to 10 pF

RMS

300 Ω 300 Ω 300 Ω 300 Ω 300 Ω

(custom) 60 db/decade 60 db/decade MEA1060-BC-PA: 20 db/decade (high pass), 60

Gain 1200 (standard), 500 to 5000 (custom) 1200 (standard), 500 to 5000 (custom) 1100 (standard), 500 to 5000 (custom) 1100 (standard), 500 to 5000 (custom) 1000

Typical switch enable time n/a n/a 20 ns 20 ns n/a

Heating element (HE)

Heating temperature Accuracy 0.1 °C 0.1 °C 0.1 °C 0.1 °C 0.1 °C Recovery time 0.5 min to 2 min 0.5 min to 2 min 0.5 min to 2 min 0.5 min to 2 min 0.5 min to 2 min Typical time constant 50 s 50 s 50 s 50 s 50 s Standard hole size 8 mm (HE-Inv-8) 17.6 mm (HE-UP) 8 mm (HE-Inv-8) 17.6 mm (HE-UP-BC) n/a Optional hole sizes 12 mm (HE-Inv-12), 23 mm (HE-Inv-23) - 12 mm (HE-Inv-12), 23 mm (HE-Inv-23) - n/a Input voltage max 10 V max 10 V max 10 V max 10 V max 10 V Input current max 2 A max 2 A max 2 A max 2 A max 2 A Temperature sensor PT 100 PT 100 PT 100 PT 100 PT 100 Resistance Thermal resistance 6 °C / Watt 6 °C / Watt 6 °C / Watt 6 °C / Watt 6 °C / Watt Calibration constant

Ambient temperature (min 10 °C) to 50 °C Ambient temperature (min 10 °C) to 50 °C Ambient temperature (min 10 °C) to 50 °C Ambient temperature (min 10 °C) to 50 °C Ambient temperature (min 10 °C) to 50 °C

15 ± 2 Ω 15 ± 2 Ω 15 ± 2 Ω 15 ± 2 Ω 15 ± 2 Ω

T = c * (R-R

)/R0 for c = 259.7 °C T = c * (R-R0)/R0 for c = 259.7 °C T = c * (R-R0)/R0 for c = 259.7 °C T = c * (R-R0)/R0 for c = 259.7 °C T = c * (R-R0)/R0 for c = 259.7 °C

MEA1060 Amplifiers are for use with two-dimensional 60-electrode microelectrode arrays (MEA). MEA 96-Well Amplifier is for use with 96-well plates with integrated recording electrodes (QT-Well plates).

165 mm x 165 mm x 14.5 mm (19 mm with sockets)

± 4 mV (with respect to the standard gain of

1200)

< 800 nV

RMS

1 Hz to 3 kHz (standard), 1 Hz to 10 kHz (custom)

165 mm x 165 mm x 20 mm (29 mm with sockets)

± 4 mV (with respect to the standard gain of

1100)

< 800 nV

RMS

1 Hz to 3 kHz (standard), 1 Hz to 8 kHz (custom)

db/decade (low pass); FA60S-BC: 20 db/decade (high pass), 80 db/decade (low pass)

196 mm x 184 mm x 17.5 mm

± 4 mV (with respect to the standard gain of

1100)

< 800 nV

RMS

1 Hz to 3 kHz (standard), 1 Hz to 8 kHz (custom) MEA1060-BC-PA: 20 db/decade (high pass), 60 db/decade (low pass); FA60S-BC: 20 db/decade (high pass), 80 db/decade (low pass)

± 4 mV (with respect to the standard gain of

1000)

< 800 nV

RMS

HznV /HznV /HznV /HznV / HznV /

0.6 Hz to 2.2 kHz

60 db/decade (low pass), 40 db/decade (high pass)

(separate lid and bottom heating)

Microscope compatibility Inverse microscopes Upright** microscopes Inverse microscopes Upright** microscopes n/a

Distance focal plane to microscope table 3.5 mm 8 mm 3.5 mm 9.5 mm

MEA1060 amplifiers are available for inverted microscopes and upright microscopes, MEA1060-INV and MEA1060-UP, respectively. **= MEA1060-UP amplifiers were optimized for upright microscopes, but can also be used for inverted microscopes, provided that the focal plane is compatible with the microscope objective. This is useful whenever an excellent accessibility of the MEA from the top is required. With an MEA1060-UP, the MEA culture chamber is the only limiting parameter for accessibility. The opening in the base plate of the amplifier is circular and hemispherical to follow the dimensions of an objective. The largest opening at the bottom is 35 mm in diameter.

MEA1060 Amplifiers can be ordered with any gain and bandwidth configurations by the user's choice. The name specifies the configuration. The first number after the microscope type specifies the gain, followed by the lowest frequency, and followed by the highest frequency. For example, MEA1060-Inv-5000-300-3000 stands for a MEA1060 amplifier for inverted microscopes with a gain of 5000, and 300 Hz to 3 kHz bandwidth. MEA1060-BC operates software-controlled and features a blanking circuit that prevents stimulus artifacts.