D150, X-Press Liquid Wax (21-133A), D15001
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isothiazol-3-one
Mixture of 5-chloro-2-methyl-2Hisothiazol-3-one and 2-methyl-2Hisothiazol-3-one
Ingestion Not toxic to development Rat NOAEL 15
mg/kg/day
during
organogenesis
Target Organ(s)
Specific Target Organ Toxicity - single exposure
Name Route Target Organ(s) Value Species Test result Exposure
Duration
Naphtha (petroleum),
hydrotreated heavy
Inhalation central nervous
system depression
May cause drowsiness or
dizziness
Human
and
animal
NOAEL Not
available
Naphtha (petroleum),
hydrotreated heavy
Inhalation respiratory irritation Some positive data exist, but the
data are not sufficient for
classification
NOAEL Not
available
Naphtha (petroleum),
hydrotreated heavy
Inhalation nervous system Some positive data exist, but the
data are not sufficient for
classification
Dog NOAEL 6.5
mg/l
4 hours
Mixture of 5-chloro-2methyl-2H-isothiazol-3one and 2-methyl-2Hisothiazol-3-one
Inhalation respiratory irritation Some positive data exist, but the
data are not sufficient for
classification
similar
health
hazards
NOAEL Not
available
Specific Target Organ Toxicity - repeated exposure
Name Route Target Organ(s) Value Species Test result Exposure
Duration
Naphtha (petroleum),
hydrotreated heavy
Inhalation nervous system Some positive data exist, but the
data are not sufficient for
classification
Rat LOAEL 4.6
mg/l
6 months
Naphtha (petroleum),
hydrotreated heavy
Inhalation kidney and/or
bladder
Some positive data exist, but the
data are not sufficient for
classification
Rat LOAEL 1.9
mg/l
13 weeks
Naphtha (petroleum),
hydrotreated heavy
Inhalation respiratory system Some positive data exist, but the
data are not sufficient for
classification
Multiple
animal
species
NOAEL 0.6
mg/l
90 days
Naphtha (petroleum),
hydrotreated heavy
Inhalation bone, teeth, nails,
and/or hair | blood |
liver | muscles
All data are negative Rat NOAEL 5.6
mg/l
12 weeks
Naphtha (petroleum),
hydrotreated heavy
Inhalation heart All data are negative Multiple
animal
species
NOAEL 1.3
mg/l
90 days
Ceramic materials and
wares, chemicals
Inhalation pulmonary fibrosis Some positive data exist, but the
data are not sufficient for
classification
Multiple
animal
species
NOAEL not
available
Ceramic materials and
wares, chemicals
Inhalation respiratory system Some positive data exist, but the
data are not sufficient for
classification
Human NOAEL not
available
occupational
exposure
Aspiration Hazard
Name Value
Naphtha (petroleum), hydrotreated heavy Aspiration hazard
Please contact the address or phone number listed on the first page of the SDS for additional toxicological information
on this material and/or its components.
SECTION 12: Ecological information
The information below may not be consistent with the material classification in Section 2 if specific ingredient classifications
are mandated by a competent authority. Additional information leading to material classification in Section 2 is available
upon request. In addition, environmental fate and effects data on ingredients may not be reflected in this section because an
ingredient is present below the threshold for labelling, an ingredient is not expected to be available for exposure, or the data
is considered not relevant to the material as a whole.