Medtronic A820 Programming Guide

myPTM™ App and Personal Therapy Manager
for the SynchroMed II Infusion System
Clinician Guide for App Version 1.0
Rx only
A820
Medtronic, SynchroMed, myPTM, N'Vision and the Medtronic logo are trademarks of Medtronic.
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word mark and logos are registered trademarks owned by Bluetooth
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and Wi-Fi Alliance® are registered trademarks of Wi-Fi Alliance.
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Table of contents

Description 7
Indications for Use 8
Information for prescribers 8
Individualization of Treatment 8 Contraindications 9 Warnings 9 Precautions 9 Adverse events summary 9
Patient management and training 9
Patient management 9 Patient training 10
Using the myPTM app 11
Preparing the PTM for first time use 12
Programming the pump for patient-activated dosing 12
Model A810 SynchroMed II Clinician Programmer 12 Model 8840 N'Vision Clinician Programmer and the Model A820 myPTM app 12
Pairing the PTM with the pump 16
Generating reports 16
Reports 16
Removing pairing 17
Removing pairing between the PTM and pump 17
Software information 18
Refer to the personal therapy manager patient user guide for warnings and precautions directed to your patient.
Refer to the handset materials for charging and setup information. Refer to communicator instructions for usage information and warnings and cautions
directed to your patient. Refer to the indications, drug stability, and emergency procedures reference manual for
indications and related information. Refer to the implantable infusion system information for prescribers manual for
contraindications, warnings, precautions, and adverse events summary. Refer to the appropriate drug labeling for indications, contraindications, warnings,
precautions, dosage and administration information, and screening procedures.
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Data security 18 Software installation and updates 18 Supporting apps 18 Disposal 19
Troubleshooting problems with the PTM 19
Reviewing alert messages 19 Troubleshooting pump alarms and alerts 20 Replacing the communicator 21
Bibliography 23
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Description

The Medtronic Model A820 myPTM app is an accessory for the Medtronic SynchroMed II Infusion System. The myPTM app is part of the Model TH90 Personal Therapy Manager (PTM), which also includes the Model HH90 handset and the Model TM90 communicator. The PTM can be used only with the SynchroMed II pump and allows the patient to activate delivery of physician-programmed supplemental doses of medication.
The PTM, including the handset, communicator, and myPTM app, are not intended for use by more than one patient. There are not any restrictions on locations where the PTM can be used.
Table 1. Abbreviations used in this manual
Abbreviation Explanation
app software application
EMI electromagnetic interference
PA patient-activated
PTM Personal Therapy Manager, including handset, myPTM app, and
Button Details and actions
communicator
Table 2. myPTM app buttons
About button: Tap to view information about the PTM and pump.
Bell button: Tap to view alert messages.
Deliver Bolus button: Tap to request a bolus.
Information button: Tap to view more information.
Menu button: Tap to view menu options.
Pairing button: Tap to remove pairing between the app and the pump.
Reports button: Tap to open the reports screen.
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Table 2. myPTM app buttons (continued)
Button Details and actions
Resync/ Retry button: Tap to refresh communication between myPTM
app and the pump. SWITCH COMMUNICATOR button: Tap to pair a different communicator.
Therapy Details button: Tap to view information about the patient's prescription.
Tutorials button: Tap to view the tutorial video.

Indications for Use

The Personal Therapy Manager allows the patient to activate delivery of physician programmed supplemental doses of preservative-free morphine sulfate sterile solution from the SynchroMed II Infusion System for the treatment of chronic intractable pain.

Information for prescribers

Individualization of Treatment

The PTM is intended for use with the SynchroMed II Infusion System in patients who fit all of the following criteria:
Patients who are able to understand the instructions for using the PTM
Patients who are able to effectively perform the tasks required to use the PTM
Patients who are psychologically competent as determined by the clinical team
Patients who have a pump that is implanted less than 2.5 cm (1 inch) from the
surface of the skin
In addition, the PTM is intended for use in pain patients who fit one of the following criteria:
Patients who experience intermittent pain of varying intensity that cannot be
adequately managed with Simple Continuous mode or Flex mode infusions Patients who have an unpredictable need for varying doses of drug
Patients who experience inadequate pain relief or intolerable side effects from
supplemental systemic pain medications
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Contraindications

Opioid naïve patients - Do not use the Personal Therapy Manager in patients who are
opioid naïve. Opioid naïve patients have a greater risk of central nervous system effects, including respiratory depression (up to 24 hours post-dosing)
1
.

Warnings

Bolus delivery of ziconotide - Do not prescribe or use the Personal Therapy Manager
for administration of an intrathecal infusion of ziconotide. The use of ziconotide with the Personal Therapy Manager has not been studied. Refer to the ziconotide labeling for adverse events, contraindications, warnings, precautions, and dosage and administration information.

Precautions

Breakthrough pain - The safety and efficacy of the Personal Therapy Manager for
breakthrough pain have not been demonstrated.
Communication interference from EMI - Electromagnetic interference (EMI) is a field of energy made by equipment found in the home, work, medical, or public environments. EMI may be strong enough to interfere with the connection between the handset and implanted device. If EMI is disrupting the connection, move away from or turn off the likely source of EMI.

Adverse events summary

A prospective clinical study of an earlier generation of the Personal Therapy Manager was conducted in 184 patients. There were no adverse events attributed to the Personal Therapy Manager. The following adverse events considered related to intrathecal morphine were reported in this study: nausea/vomiting, constipation, urinary retention, daytime drowsiness, itching/pruritus, sedation, sleep difficulty, confusion, euphoria, withdrawal symptoms, diaphoresis, edema, allergic reaction, dysphoria, fall, headache, shortness of breath, weight gain, and use of wrong drug in the pump. There were 2 deaths in the study; both were determined to be not device related
In a published, peer-reviewed report of bolus doses with continuous infusion of intrathecal morphine, similar drug related adverse events were reported
2
.
3
.

Patient management and training

Patient management
Follow the patient management recommendations:
A period of observation appropriate to the clinical situation should follow the first
patient-activated dose of intrathecal morphine, unless the patient previously has received a comparable dose via Flex Mode or via a physician-activated bolus. Instruct the patient to contact you if they experience opioid adverse reactions or
overdose symptoms. Refer to the appropriate drug labeling for adverse reactions and overdose symptoms.
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Patient training
The myPTM app does not require previous skills or knowledge to use. However, patients may need a demonstration of the PTM. Ensure you take the following suggested steps with the patient:
Review warnings and precautions in the patient manual.
Explain patient-activated dosing, the patient’s prescription, and when the patient
should use their available boluses. Demonstrate how to hold the communicator and handset (Figure 1 on page 11).
Either side of the communicator can be placed against the pump. Demonstrate how to turn on the PTM components, how to request a bolus, and how
to check the status of the infusion system. Refer to the PTM patient manual and the tutorial video within the myPTM app for instructions. Explain that the patient should schedule a drug refill before the expected refill date
shown in the myPTM app. The expected refill date is an estimated date of when the low reservoir alarm will sound. The date may change, depending on how frequently boluses are delivered.
Note: By default, a tutorial video runs each time the myPTM app opens and successfully establishes communication with the pump.
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Using the myPTM app

Warning: Do not place the communicator over another medical device (for example,
pacemaker, defibrillator, neurostimulator, another pump). The Personal Therapy Manager could change the operation of the other device.
Notes:
The communicator and handset must be charged and turned on to communicate
with the pump.
When the communicator is turned on, the BLUETOOTH® technology indicator appears blue. The communicator will not connect to the pump while it is charging.
Place either side of the communicator directly over the pump (Figure 1).
1.
Communicator Pump Handset
Figure 1. Position of the handset and communicator next to the patient's pump.
From the handset main screen, tap to open the myPTM app icon (Figure 2).
2.
myPTM™
Figure 2. myPTM app icon.
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Preparing the PTM for first time use

Before giving the PTM to your patient, complete the following tasks:
Program the pump for patient-activated dosing. Refer to the programming
instructions starting on page 12. Pair the PTM with the pump. Refer to the instructions on page 16.
Show the patient how to use the PTM. Refer to "Patient management and
training" on page 9.

Programming the pump for patient-activated dosing

Warning:
Do not rely on the Personal Therapy Manager as the main source of medications that produce severe underdosing effects. The Personal Therapy Manager is intended to provide supplemental doses of medication. If the Personal Therapy Manager is lost or it is not functioning properly, the patient may experience a loss of or change in therapy, which may lead to a return of underlying symptoms, drug withdrawal symptoms, serious injury or death.
Warning:
Do not use or prescribe more than one Personal Therapy Manager (of any model) with a single pump. A drug overdose may occur if a request for a bolus dose is made using more than one Personal Therapy Manager because the pump may deliver more bolus doses than prescribed within a given dose restriction interval, resulting in serious patient injury or death.
Clinicians prescribing a PTM should be experienced with the principles of pain management, including chronic neuraxial opioid analgesia and with the operation of the SynchroMed II Infusion System.
Notes:
Patient-activated boluses will not be available after a pump update for the
duration of the lockout interval or the dose restriction interval, whichever is longer. If patient-activated dosing is disabled in the pump, the myPTM app remains
paired to the pump.
Model A810 SynchroMed II Clinician Programmer
For programming instructions, see the A810 SynchroMed II Clinician Programmer programming guide.
Model 8840 N'Vision Clinician Programmer and the Model A820 myPTM app
Before the PTM can be used, the pump must be programmed to Infusion PA (patient­activated) mode. This initial programming is performed using the clinician programmer.
Notes:
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To enable patient-activated dosing, the pump must be programmed to Simple
Continuous Mode. The dose per day entered on the Simple Continuous data entry screen is the
basal rate of the infusion prescription except when a physician-activated or patient-activated bolus is active. If appropriate, program other pump parameters before programming the pump
for patient-activated dosing. (For instructions, refer to the clinician programming guide.)
To program the pump for patient-activated dosing:
1.
Using the clinician programmer, select the
2.
Select the mode is selected and a dose is entered.
3.
Select the From the
4. PA
Note:
concentration of the primary reservoir contents and the 24-hour infusion dose.
Infusion Mode
Infusion PA
Infusion PA
data entry screen appears.
Valid ranges for
sub tab ( ) and ensure that
sub tab ( ).
drop-down list (Figure 3), select
PA Dose
and
Infusion
screen tab ( ).
PA Enabled
Maximum Daily Dose
Simple Continuous
are based on the
. The
Infusion
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Infusion PA drop-down list
Drug drop­down list
Figure 3. Infusion PA drop-down list and data entry screen.
If the primary drug is not displayed, select the primary drug from the drug drop-down
5.
list (Figure 3). The default setting is the primary drug.
Notes:
Patient activated dosing is based on the primary drug.
To view calculations for a secondary drug, select the secondary drug from the
drug drop-down list. Secondary drug information is for reference only.
Enter the patient-activated dose:
6.
a. Select the
b. Enter the dose.
c. Select the
Enter the patient-activated dose duration:
7.
a. Select the
b. Enter the duration of the patient-activated dose.
c. Select the
PA Dose input box.
OK button.
PA Duration input box.
OK button.
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Notes:
Some dose and duration combinations may not be possible because of the
pump system design. The default setting is the time required to deliver the dose at the maximum
infusion rate.
Enter the PA Lockout Interval:
8.
a. Select the
b. Enter the minimum time between patient-activated doses.
c. Select the
Notes:
The PA Lockout Interval can range from 10 minutes to 23 hours, 30 minutes.
The PA Lockout Interval cannot be shorter than the patient-activated dose duration. The PA Lockout Interval is the minimum time between patient activated doses.
Enter the dose restriction interval (maximum number of patient-activated doses in a
9.
specified period of time):
a. Select the
b. Enter the maximum number of patient-activated doses and the period of time in
which the doses are allowed.
c. Select the
Enter the maximum number of patient-activated doses per day (midnight to
10.
midnight):
a. Select the
b. Enter the maximum number of patient-activated doses per day.
c. Select the
11.
Review the calculated dosages displayed on the Infusion PA sub tab ( ):
The total maximum daily dose
Increase in daily dose
Note: The refill date is an estimated date, based on the maximum number of patient-
activated doses available to the patient per day and the infusion rate of therapy. The date may change, depending on how frequently boluses are delivered.
If you are finished setting pump parameters, update the pump.
12.
a.
Select the
b. Select the
PA Lockout Interval input box.
OK button.
Dose Restriction Interval input box.
OK button.
Maximum Activations/Day input box.
OK button.
Summary screen tab ( ).
Update Pump button.
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Pairing the PTM with the pump

The PTM, which includes the myPTM app, handset, and communicator, must be paired with the pump before the PTM can be used for patient-activated dosing.
1.
Tap to open the myPTM app icon ( ) if it is not already open. When the myPTM app says that no pump is paired with the handset, tap PAIR TO
2.
3.
4.
5.
6.
For troubleshooting communication issues, refer to "Troubleshooting problems with the PTM" on page 19. For additional information, see the communicator instructions.
.
PUMP
If this is the first time the communicator and handset are used together, check the serial number on the back of the communicator. Reposition the communicator next to the pump.
After the myPTM app detects the communicator, select the communicator serial number by tapping the check box. Press
On the PUMP FOUND screen, compare the serial number of the pump with the serial number in the patient’s records.
Tap COMPLETE PAIRING to pair the handset, communicator, and the pump.
CONTINUE.

Generating reports

Reports
The REPORTS screen provides the ability to view, print, and save the Dosing Report and the Technical Report. The reports show the data collected for the past 90 days or since the last time the pump was updated by a clinician programmer.
Both types of reports include this information:
Bolus Summary: A summary of boluses requested, boluses given, boluses
denied, and average bolus dose per day for the primary drug. It also includes the total number of boluses available since the last update by a clinician programmer. Last Updated Date: Date of the last update by a clinician programmer.
Dosing Report includes this information:
The
Bolus Use: Chronological list of boluses that were requested and given.
Bolus Lockout Settings: Prescribed lockout duration, maximum activations per
day, and dose restriction interval. Bolus Dose: Drug name, the dose that is delivered, and the bolus duration.
Total Dose/Day: Name of drug, the 24-hour dose when no boluses are given (NO
BOLUS), and the 24-hour dose when all boluses are given (MAXIMUM).
Technical Report includes this information:
The
PTM Log: Chronological list of bolus requests and denials, and recorded pump
alarms or alert messages.
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PTM Information: Model number and version number of the myPTM app. The
handset serial number and version of the operating system are also listed. Pump Information: Model number and serial number of the pump.
Note: All downloaded reports are deleted from the default folder after 24 hours.
From the action bar, tap ( ) to open the menu (Figure 4).
1.
2.
Select Reports from the menu. From the REPORTS screen, select a type of report: Dosing Report or Technical
3. Report
.
Select one of the actions shown on the REPORTS screen (Table 3).
4.
When an action is selected, a pop-up screen allows the option to remove the
5.
patient's name, the last updated date, and the pump serial number from the report.
Tap to open menu Tap to view alert messages
Figure 4. myPTM app HOME screen action bar.
Table 3. REPORTS screen actions
Button Details
View
button (to view a PDF of the report)
Share
button (feature disabled)
Download
handset).
button (to save a PDF of the report to a default location on the

Removing pairing

Removing pairing between the PTM and pump
Complete the steps to remove pairing when disconnecting the PTM from a specific pump, such as during a pump replacement. Refer to "Preparing the PTM for first time
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use" to program the newly implanted pump for PTM use and to pair the PTM with the pump.
Notes
:
Reports saved to the default location on the handset will be deleted after
completing the following steps. To complete the following steps, contact Medtronic to obtain an authentication
key. Contact information for Medtronic is found at the end of this manual.
From the action bar, tap to open the menu (Figure 4).
1.
2.
Select Note the code found on the screen and provide this code to Medtronic to obtain an
3.
authentication key. On the
4.
representative. Tap
5.
Tap the OK button to confirm that all the app data will be removed from the handset.
6.
Pairing
from the menu.
AUTHENTICATION
REMOVE PAIRING
screen, type in the key provided by the Medtronic
to confirm.

Software information

Data security
The myPTM app uses and stores data about the patient’s health and their implanted medical device. This information is protected by encryption within the app and encryption provided by the handset.
Medtronic recommends the following security measures for both you and your patient:
Always save data exported from the app to the default location.
Secure the handset by disabling the Wi-Fi connection when using the myPTM app.
Use a managed, trusted Wi-Fi connection when network connectivity is needed.
Software installation and updates
The myPTM app along with supporting software apps are provided pre-installed on the Android platform-based handset and cannot be installed on a personal cellular phone.
Software and firmware updates may be sent to the handset.
Supporting apps
There are other apps installed on the handset that support the Model A820 myPTM app. The Model A901 Communication Manager app works with the myPTM app to manage communication between the handset and the pump. The Model A902 Patient Data
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Services app works with the myPTM app to retrieve data from the pump and generate reports.
Disposal
Patients should call Medtronic if they will no longer be using the handset to manage their therapy. If the patient returns the handset to you, contact Medtronic for assistance with deleting patient data from the handset. Contact information for Medtronic is found at the end of this manual.

Troubleshooting problems with the PTM

This section provides information for noninvasive troubleshooting.
Reviewing alert messages
The patient uses the PTM to view alert messages, which includes information about pump alarms or telemetry issues. The myPTM app automatically detects alerts when it communicates with the pump.
The colored text of the alert message pop-up screen indicates the type of alert Figure 4. If the myPTM app has not recently communicated with the pump, interrogate the pump to
retrieve any active alert messages:
1.
From the
HOME
screen, tap ( ) to open the menu (Figure 4). Select
Review the alert message and follow the instructions.
2.
Note
: Refer to Table 5 for alert messages that require additional explanation.
If you experience an issue not described in this section, contact Medtronic. Contact
3.
information for Medtronic is found at the end of this manual.
Note
: Active alert messages can be retrieved at any time by tapping the alert button
), located in the upper right corner of the action bar.
(
Table 4. Type of alert
Button Details
Information
(blue): provides information about functionality or status.
Resync
.
Caution
(orange): the message must be acknowledged or resolved.
Warning
(red): indicates the presence of a potentially hazardous condition or a condition that would prevent use of the app. The warning alert must be acknowledged or resolved.
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Troubleshooting pump alarms and alerts
To resolve pump alarms, follow these steps:
Check the pump status by interrogating the pump with a clinician programmer. Refer
1.
to the clinician programming guide for instructions. Follow the directions in the alert message displayed by the clinician programmer.
2.
Review the pump event logs or activity logs for additional information about the
3.
pump alarm.
Note:
The event logs display the number of successful and unsuccessful patient-
activated dosing attempts made since the last pump update.
When the clinician programmer interrogates the pump, the number of successful and
4.
unsuccessful patient-activated dosing attempts made since the last pump update is updated and displayed under event logs on the clinician programmer, in addition to PTM reports.
Alert messages that need additional explanation and possible solutions are found in
5.
Table 5. If you experience an issue not described in this section, contact Medtronic. Contact
6.
information for Medtronic is found at the end of this manual.
Table 5. Alert messages with additional explanation
Alert code
91,
Communication error. Retry
141,
communication. If issue persists,
356
contact Medtronic for assistance.
351 Incompatible Pump Found: The
pump found is not paired with the handset. Please move the communicator over the paired pump.
Alert text Possible solutions
The communicator stopped communicating with the pump before the bolus was started.
Verify that the communicator is turned
on and fully charged.
Tap
Resync
.
Place the communicator next to the pump that is paired.
If the problem persists, verify that the myPTM app is paired to the patient's pump:
Tap to open the menu.
Tap
About
to view the serial number. Compare the pump serial number
found in the myPTM app with the one listed in the patient's record.
and select the
PUMP
tab
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Table 5. Alert messages with additional explanation (continued)
Alert code
364 Bolus Rejected: A clinician bolus
is in progress. Please wait until the bolus is complete.
372 Pump memory error has
occurred. myPTM configuration is invalid. Contact your clinician for assistance.
373 Dose restriction interval is
currently active.
None Communicator not found
None No Pump Found
None Patient bolus is disabled. Repeat the steps to program the pump for
Alert text Possible solutions
Physician-activated boluses (priming, single, and bridge boluses) take precedence over patient-activated dosing requests and programmed infusion settings. Wait until the physician-activated bolus is completed before repeating the bolus request.
Repeat the steps to program the pump for patient-activated dosing.
Bolus requests are not available while the dose restriction interval is active. Wait until the lockout period is completed before repeating the bolus request.
Follow on-screen instructions for
troubleshooting. Unplug the communicator from the
charging cable. The communicator will not connect to the pump while it is charging. Tap
Retry
refresh the connection.
The communicator must be 2.5 cm
(1 inch) or less from the pump.
Tap
patient-activated dosing.
. If the problem persists, tap
SWITCH COMMUNICATOR
Retry
.
to
Replacing the communicator
Complete these steps when the communicator must be replaced with a different one. Refer to "Pairing the PTM with the pump" on page 16 when replacing both the handset and the communicator.
From the myPTM app
1.
on page 17). Select
HOME
screen action bar, tap ( ) to open the menu (Figure 4
Resync
.
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The myPTM app automatically searches for the paired communicator.
2.
3.
When the myPTM app states that the communicator is not found, tap the
SWITCH COMMUNICATOR
Check the serial number on the back of the communicator. Reposition the
4.
communicator next to the pump. After the new communicator is detected, select the communicator serial number by
5.
tapping the check box. The
HOME
6.
the pump.
screen displays. This confirms that the new communicator is paired with
button.
For troubleshooting the connection between the myPTM app and the pump, refer to "Troubleshooting problems with the PTM" on page 19. For additional information, see the communicator instructions for use.
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Bibliography

Coffey RJ, Owens ML, Broste SK, Dublis MY, Ferrante FM, Schultz DM, Stearns LJ,
1.
Turner MS. Medical practice perspective: identification and mitigation of risk factors for mortality associated with intrathecal opioids for non-cancer pain. Pain Medicine. 2010;11:1001-1009.
IDE clinical study; data on file; Medtronic, Inc.
2.
Ilias W, le Polain B, Buchser E, Demartini L. Patient-controlled analgesia in chronic
3.
pain patients: experience with a new device designed to be used with implanted programmable pumps. Pain Practice. 2008;8(3):164-170.
 2018-06-01 myPTM™ App and Personal Therapy Manager A820 English 23
Manufacturer
Medtronic, Inc. 710 Medtronic Parkway Minneapolis, MN 55432-5604 USA www.medtronic.com Tel. 1-763-505-5000 Toll-free 1-800-328-0810
*M969547A002*
© Medtronic 2018 All Rights Reserved
M969547A002 Rev A
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