Masterflex 74000-59 Instruction Manual

®

Operating and Installation Manual:

QUATTROFLOW 1200SU EZ-SET

SINGLE USE QUATERNARY PUMP

4 PISTON-DIAPHRAGM PUMP

Model No.

74000-59

Model 74000-59

Edition 05

A-1299-7369

(US & Canada only) Toll Free 1-800-MASTERFLEX • 1-800-637-3739
(Outside US & Canada) 1-847-549-7600 • 1-847-381-7050
www.masterflex.com • [e-mail]

Preface

© 2019 Cole-Parmer Instrument Company. All rights reserved.

Masterflex — Reg TM Cole-Parmer Instrument Company.

© 2019 ALMATEC. Quattroflow is a trademark of ALMATEC MASCHINBAU Gmbh.

Trademark bearing the ® symbol in this publication are registered in the U.S. and in other countries.

Modifi cations of the design or materials may be made without prior notice.

ORIGINAL INSTRUCTIONS

PUMP FOR LIQUIDS

ii A-1299-7369

Masterflex

Preface

Explanation of Symbols

Explanation of

Symbols

Please read this manual carefully before start-up of the pump and
take note of the appropriate instruction in the operating manual. See
SECTION 3 for detailed safety instruction. See drive manual for more
safety instructions.

CAUTION: Risk of danger. Consult operator’s manual for nature

!

of hazard and corrective actions.

CAUTION: Risk of injury. Keep fingers away from the coupling
while shaft is rotating. Do not operate without pump head
installed.

CAUTION: Hot surface. Do not touch.

CAUTION: Risk of electric shock. Consult operator’s manual for
nature of hazard and corrective actions.

CAUTION: Please follow the general guidelines and safety
instructions when handling with chemicals.

WARNING:

Product Use

Limitation

!

CAUTION: During all maintenance work it has to be ensured
that no explosive atmosphere can arise. Appropriate protection
equipment is recommended. The Quattroflow 1200 SU must not be
operated in explosion-proof areas. Special versions for “ATEX”
applications are available. Please contact manufacturer.

This product is not designed for, nor intended for use in patient
connected applications; including, but not limited to, medical
and dental use, and accordingly has not been submitted for FDA
approval.

This product is not designed for, nor intended for use in
hazardous duty areas as defined by ATEX or the NEC (National
Electrical Code); including, but not limited to use with
flammable liquids. Consult the factory for products suitable for
these types of applications.

Masterflex iii

A-1299-7369

Table of Contents

Contents

Page

Section 1

Section 2 QF1200 SU EZ-SET PUMP DESCRIPTION . . . . . . . . . . . . . . . . . . . . . . . . .2-1

Section 3 SAFETY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

GENERAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Storage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Labeling of the Pump . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Appropriate Use . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

General Description of the Machine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Start-Up . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Cleaning (CIP) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Autoclave . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Gamma Irradiation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Labels on the Pump . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Qualified Personnel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Safety Guidelines . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Failure to Follow Safety Instructions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Safety Hints for the Operator . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Safe Maintenance, Inspection, and Mounting Operations . . . . . . . . . . . . . .

Unauthorized Modifications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Invalid Modes of Operation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Additional Safety Warnings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

1-1

1-1
1-1

1-2

2-1

2-1
2-2
2-3
2-3
2-3

3-1

3-1

3-1
3-1
3-1

3-1
3-2
3-2
3-2
3-3

Masterflex

Section 4

Section 5

Section 6

Section 7

MAINTENANCE/SERVICING . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Replacing Pump Chamber . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Disassembling Pump Chamber . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Assembling Pump Chamber to the Ring Drive . . . . . . . . . . . . . . . . . . . . . . .

Replacing Bearing Unit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Disassembling Ring Drive . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Assembling Ring Drive . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

TROUBLESHOOTING . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

PERFORMANCE CHARTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

TECHNICAL DATA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

4-1

4-2
4-2
4-3
4-5
4-5
4-6

5-1

6-1

7-1

vA-1299-7369

Section 1 General

Section 1

General

Introduction

 ese operating instructions are valid for the Quattrofl ow 1200SU EZ-SET
pump. No liability will be undertaken for any damages caused be non­compliance with the operating instructions and service conditions! Original
spare parts serve safety purposes.  e use of other parts may cancel the
liability for the consequences and secondary failures resulting there of.

Drive Manufacturer: Cole-Parmer
650 East Bunker Ct

Vernon Hills, IL 60061 USA
Phone: [phone]
Email: [e-mail]
Internet: www.coleparmer.com

Pump Manufacturer: ALMATEC Maschinenbau GmbH

Carl-Friedrich-Gauss-Str. 5
D-47475 Kamp-Lintfort, Germany

Quattrofl ow quaternary diaphragm pumps are constructed according to
the state of the art and they are reliable. Imminent danger by operating
error or misuse can lead to damages of properties and/or persons. The
pumps are to be applied for the intended use in a safety-related proper
condition only.

Storage

In general the Quattrofl ow pump is delivered operational and packaged.
If the unit is not installed right away, proper storage conditions are impor­tant for trouble free operation later. The pump has to be protected from
wetness, coldness, dirtying, UV-radiation and mechanical infl uences. The
following storage conditions are recommended:

-Steady ventilated, dust and vibration free storage room

-Ambient temperature between 15°C (59°F) and 25°C (77°F) with a
relative humidity below 65%.

-Prevention of direct thermal infl uences (sun, heating).

Masterflex 1-1A-1299-7369

Section 1

General

Labeling of the Pump

 e ALMATEC Machinenbau GmbH is certifi ed as a modern, quality­orientated enterprise according to DIN EN ISO 9001:2008 and
1400:2009. Before release for sale, any Quattrofl ow pump has to undergo
an extended fi nal control.  e performance data registered during this are
archived in our records and can be read back at any time.

As a general rule in the countries of the EU only such machines are allowed
to be placed into operation, which are determined to meet the regulations
of the EU machinery directive, the harmonized standards, European
standards and the respective national standards. Hence the operator has to
verify whether the Quattrofl ow pump manufactured and delivered properly
according to the customers order meets the mentioned requirements.

 erefore make sure, before putting the pump into operation, that the
pump and the used materials of construction are suitable for the provided
application and the installation site.

 e type label of each Quattrofl ow pump can be seen on the bottom of
the pump.  e serial number of the pump head is fi xed the bottom of the
pump.

Masterflex Pump Drive

For further information on the pump drive system see within this
flash drive or on the web.

1-2 A-1299-7369

Masterflex

Section 2 QF1200 SU EZ-SET Pump

Description

Section 2

QF1200 SU EZ-SET

Pump Description

Appropriate Use

 e Quattrofl ow 1200 SU EZ-SET is a 4 piston-diaphragm pump, which
is mainly used to pump water-like fl uids that are typically handled in
research, pilot plant or production facilities of the pharmaceutical, biotech,
food or cosmetic research centers or plants.

Examples:

• Solutions containing protein (albumin, IgG, Clotting factors monoclonal,

enzymes, vaccines.)

• Solutions of polymers or suspensions (silicon, latex, chromatography media)

• Cell suspensions (bacteria, yeast, algae, fungi, mammalian cells)

• Colloidal solutions

• Suspensions of viruses or phage

Typical applications for the QF1200 SU EZ-SET

- Filtration technology:

• To recirculate feed/retentive (e.g. membrane cassettes, hollow fi bre, spiral
wound, ceramic elements).

• Feed Pump for fi lter cartridges or plate and frame depth fi lters

- Chromatography:

• Packing of chromatography columns

• Feed pump to mix gradients

General Description of

the Machine

Masterflex

- Feed pump for centrifuges or separators

- Feed pump for fi lling machines

- Feed pump homogenizers

 e Quattrofl ow 1200SU EZ-SET pump is a 4 piston-diaphragm pump.
 e four segments of the pump diaphragm oscillate back and forth.  is
alternate movement is created by a connector plate that is arranged on
a ball bearing.  e ball bearing sits on an eccentric shaft.  e connector
plate does not turn!

 e stroke of the piston is determined by the angle of the eccentric.  ere
are eccentric shafts with 5°.

Range of Flow Rate:
5° eccentric shaft: approximate 20-1200 L/hr

In Gallons:
5° eccentric shaft: approximate 5.3-317 gph

2-1A-1299-7369

Section 2

QF1200 SU EZ-SET
Pump Description

General Description of

the Machine

(Continued)

Start-Up

Please note:

 e direction of fl ow can be adjusted by turning the pump chamber in 90° steps.
 e Quattrofl ow 1200SU EZ-SET is self-priming and can run dry. Inside the
pump chamber there are no rotating parts that might cause heating up of the

product or shed particles.

 e Quattrofl ow 1200SU EZ-SET pump is designed for use in single-use
process.  e wetted product chamber made of plastic is replaced after onetime

use.  e simple disposal of the product chamber saves time and money.  is
eliminates the eff ort for cleaning, sterilization or a sophisticated cleaning
validation. Also a cross-contamination can be excluded. Particularly in
biotechnology development stage single-use pumps facilitate and accelerate the
process preparations. Frequently changing products is generally the typical fi eld
of application of the single-use pumps.

A Quattrofl ow single-use pump is delivered pre-assembled.  ree plastic pump
chambers are supplied with each new pump unit. One of them has to be
installed according to the instructions in Section 4 (Replacing Pump Chamber),
while the other two are for a further replacement.

Before start-up of the pump one should acquaint oneself with the explanations
of the troubleshooting. Only by doing this can defects be quickly realized and
eliminated in case of trouble. Problems which cannot be solved or with an
unknown reason should be passed on to the manufacturer.

Prior to the very fi rst use it might make sense to clean and sanitize the pump
chamber. A commercial caustic clear and/or 0.1 to 0.5N NaOH can be applied.
 e chosen cleaning agent do not recirculated and also stored inside the pump
chamber. For Flushing out of any cleaning agent do not recirculate! Check with
appropriate analytical methods the success of the fl ushing procedure.

Recommendation: Test run prior first use!

!

!

Before using your pump in your process perform a test run to get
used to the specific properties of the pump.

Pay attention to have sufficiently dimensioned piping. Too small
of for the suction line can cause cavitation as well as a loss of
performance. If hoses are used in the suction line, make sure that
they do not collapse due to the negative pressure.

When installing the pump please insure that around the pump
enough space is available for the operation and maintenance.
Pay attention to the required space needed for assembly and
disassembly of the pump chamber.

During start-up pay attention to the warning and safety instructions
of the following section 3 of this manual.

2-2

MasterflexA-1299-7369