Masterflex 74000-49 Instruction Manual

®

Operating and Installation Manual:

QUATTROFLOW 150S

MULTIPLE-USE STAINLESS STEEL

QUATERNARY PUMP 4 PISTON

DIAPHRAGM PUMP

Model No.

74000-49

Model 74000-49

(US & Canada only) Toll Free 1-800-MASTERFLEX • 1-800-637-3739
(Outside US & Canada) 1-847-549-7600 • 1-847-381-7050
www.masterflex.com • [e-mail]

Edition 03

A-1299-7368

Preface

© 2019 Cole-Parmer. All rights reserved. Some material content of this manual.

Masterflex — Reg TM Cole-Parmer Instrument Company.

© 2019 ALMATEC. Quattroflow is a trademark of ALMATEC MASCHINBAU Gmbh.

Trademark bearing the symbol in this publication are registered in the U.S. and in other countries.

Modifi cations of the design or materials may be made without prior notice.

®

ORIGINAL INSTRUCTIONS

PUMP FOR LIQUIDS

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A-1299-7368

Masterflex

Preface

Explanation of Symbols

Explanation of

Symbols

Please read this manual carefully before start-up of the pump and
take note of the appropriate instruction in the operating manual. See
SECTION 3 for detailed safety instruction. See drive manual for more
safety instructions.

!

CAUTION: Risk of danger. Consult operator’s manual for nature
of hazard and corrective actions.

CAUTION: Risk of injury. Keep fingers away from the coupling
while shaft is rotating. Do not operate without pump head
installed.

CAUTION: Hot surface. Do not touch.

CAUTION: Risk of electric shock. Consult operator’s manual for
nature of hazard and corrective actions.

CAUTION: Please follow the general guidelines and safety
instructions when handling with chemicals.

WARNING:

Product Use

Limitation

CAUTION: During all maintenance work it has to be ensured
that no explosive atmosphere can arise. Appropriate protection
equipment is recommended. The Quattroflow 150S must not be
operated in explosion-proof areas. Special versions for “ATEX”
applications are available. Please contact manufacturer.

This product is not designed for, nor intended for use in

!

patient connected applications; including, but not limited
to, medical and dental use, and accordingly has not been
submitted for FDA approval.

This product is not designed for, nor intended for use in
hazardous duty areas as defined by ATEX or the NEC (National
Electrical Code); including, but not limited to use with
flammable liquids. Consult the factory for products suitable
for these types of applications.

Masterflex

iiiA-1299-7368

Table of Contents

Contents

Page

Section 1 GENERAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Storage . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Labeling of the Pump . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Section 2

Section 3

QF150S PUMP DESCRIPTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Appropriate Use . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

General Description of the Machine . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Start-Up . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Cleaning (CIP) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Autoclave . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Steaming in Place (SIP) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

SAFETY . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Labels on the Pump . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Qualified Personnel . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Safety Guidelines . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Failure to Follow Safety Instructions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Safety Hints for the Operator . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Safe Maintenance, Inspection, and Mounting Operations . . . . . . . . . . . . . .

Unauthorized Modifications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Invalid Modes of Operation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Additional Safety Warnings . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

1-1

1-1
1-1

1-2

2-1

2-1

2-1
2-2
2-3
2-3
2-4

3-1

3-1

3-1
3-1
3-1
3-1
3-2

3-2
3-2

3-3

Masterflex

Section 4

Section 5

Section 6

Section 7

MAINTENANCE/SERVICING . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4-1

Replacing Diaphragm, Valves, and O-rings . . . . . . . . . . . . . . . . . . . . . . . . . .

Disassembling the Pump Chamber . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Exchange of the Elastomer Parts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Reassembling Pump Chamber . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Replacing Bearing Unit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

TROUBLESHOOTING . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

PERFORMANCE CHARTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

TECHNICAL DATA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

4-2
4-2

4-3

4-4

4-5

5-1

6-1

7-1

vA-1299-7368

Section 1 General

Section 1

General

Introduction

 ese operating instructions are valid for the Quattrofl ow 150S pump.
No liability will be undertaken for any damages caused be non-compli­ance with the operating instructions and service conditions! Original
spare parts serve safety purposes.  e use of other parts may cancel the
liability for the consequences and secondary failures resulting there of.

Drive Manufacturer: Cole-Parmer
650 East Bunker Ct

Vernon Hills, IL 60061 USA
Phone: [phone]
Email: [e-mail]
Internet: www.coleparmer.com

Pump Manufacturer: ALMATEC Maschinenbau GmbH

Carl-Friedrich-Gauss-Str. 5
D-47475 Kamp-Lintfort, Germany

Quattrofl ow quaternary diaphragm pumps are constructed according to
the state of the art and they are reliable. Imminent danger by operating
error or misuse can lead to damages of properties and/or persons.  e
pumps are to be applied for the intended use in a safety-related proper
condition only.

Masterflex

Storage

In general the Quattrofl ow pump is delivered operational and packaged.
If the unit is not installed right away, proper storage conditions are impor­tant for trouble free operation later.  e pump has to be protected from
wetness, coldness, dirtying, UV-radiation and mechanical infl uences.  e
following storage conditions are recommended:

-Steady ventilated, dust and vibration free storage room

-Ambient temperature between 15°C (59°F) and 25°C (77°F) with a
relative humidity below 65%.

-Prevention of direct thermal infl uences (sun, heating).

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Section 1

General

Labeling of the Pump

 e ALMATEC Machinenbau GmbH is certifi ed as a modern, quality­orientated enterprise according to DIN EN ISO 9001: 2008 and 1400: 2009.
Before release for sale, any Quattrofl ow pump has to undergo an extended
fi nal control.  e performance data registered during this are archived in our
records and can be read back at any time.

As a general rule in the countries of the EU only such machines are
allowed to be placed into operation, which are determined to meet the
regulations of the EU machinery directive, the harmonized standards,
European standards and the respective national standards. Hence the
operator has to verify whether the Quattrofl ow pump manufactured and
delivered properly according to the customers order meets the mentioned
requirements.

 erefore make sure, before putting the pump into operation, that the
pump and the used materials of construction are suitable for the provided
application and the installation site.

 e type label of each Quattrofl ow pump can be seen on the bottom of
the pump.  e serial number of the pump head is fi xed the bottom of the
pump.

Masterflex Pump Drive

For further information on the pump drive system see within this
flash drive or on the web.

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Masterflex

Section 2 QF150S Pump Description

Section 2

QF150S Pump Description

Appropriate Use

 e Quattrofl ow 150S is a 4 piston-diaphragm pump, which is mainly used
to pump water-like fl uids that are typically handled in research, pilot plant or
production facilities of the pharmaceutical, biotech, food or cosmetic research
centers or plants.

Examples:

• Solutions containing protein (albumin, IgG, Clotting factors, monoclonal,

enzymes, vaccines.)

• Solutions of polymers or suspensions (silicon, latex, chromatography media)

• Cell suspensions (bacteria, yeast, algae, fungi, mammalian cells)

• Colloidal solutions

• Suspensions of viruses or phage

• Dairy products

• Gelatin

• Supplements and ingredients for cosmetic and food

Typical applications for the QF150S

- Filtration technology:

• To recirculate feed/retentive (e.g. membrane cassettes, hollow fi bre, spiral
wound, ceramic elements).

• Feed Pump for fi lter cartridges or plate and frame depth fi lters

General Description of

the Machine

- Chromatography:

• Packing of chromatography columns

• Feed pump to mix gradients

- Feed pump for centrifuges or separators

- Feed pump for fi lling machines

 e Quattrofl ow 150S pump is a 4 piston-diaphragm pump.  e four segments
of the pump diaphragm oscillate back and forth.  is alternate movement is
created by a connector plate that is arranged on a ball bearing.  e ball bearing
sits on an eccentric shaft.  e connector plate does not turn!

 e stroke of the piston is determined by the angle of the eccentric.  ere are
eccentric shafts with 5° available.

Range of fl ow rate: 5° eccentric shaft: approx. 1-180 L/hr at max. 3000 rpm

Masterflex

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