Leica FL800
Integrated Vascular Fluorescence
Living up to Life
Pioneering Fluorescence Innovation
The development of fluorescence microscopy has a long tradition
at Leica Microsystems, dating back to the beginning of the 20th
century. Today, the successful integration of Leica Microsystems’
high-resolution surgical optics with the science of fluorescence
provides brand new possibilities in vascular procedures. Thanks
to this progress even small arteries and veins can be visualized in
real time through the optics of a surgical microscope.
The Leica FL800 vascular fluorescence
device has received FDA 510(k)
clearance for heart, plastic, and
neuro surgery. For additional
information please contact your local
Leica Microsystems representative.
This ability to monitor blood flow in tissue and vessels intra-opera-
tively during surgery can benefit surgical outcomes.
The Leica FL800’s integration with the surgical microscope makes
vascular fluorescence a seamless part of surgery.
Visualize Blood Flow
ey e
sensitivity
spectrum
emission spectrum
0.2
0.4
0.6
0.8
1.0
400 500 600 700
800
/nm
excitation
spectrum
non visible
video filter
excitation
spectrum
The Leica FL800 is used in conjunction with the fluorescent agent
IndoCyanineGreen (ICG) to view vascular blood flow directly
through the surgical microscope eyepieces or on a video monitor.
Obtaining this ICG-fluorescence information at the near infrared
(NIR) is a fast, easy procedure. To change from white light to NIR
mode, the surgeon simply pushes a button found on the pistol grip
of the surgical microscope.
The ICG Process
ICG perfusion is detectable because it excites at 800nm light and
then emits fluorescence at 835nm. The 835nm light is filtered away
from the normal white light and is detected by a special NIR
CCD-camera. The CCD-camera converts the 835nm light (invisible
to the human eye) to white light and projects it to a standard video
monitor and/or recording device.
View: White light mode
Near infrared overlay in the
left eyepiece, the anatomical view in
the right eyepiece.
ICG Spectras
The ICG Application
ICG injection
After 2 seconds:
Arterial view
ICG injection
After 5 seconds:
Capillary view
ICG injection
After 9 seconds:
Venous view
Anatomic view
Pictures taken with Leica M520 OH3 FL800
Easy to Set Up
Surgeons with experience in vascular fluores-
cence have commented that the main purpose
of ICG fluorescence lies in the visualization of
blood flow. Subsequently, this enables the sur-
geon to determine the patency of vessels during
surgery.
The smooth set-up and use of the Leica FL800
perfectly integrates into the efficient flow of
a vascular procedure. The press of a single
button on the surgical microscope activates the
Leica FL800 ICG process. The fluorescence is
then filtered through Leica Microsystems’ supe-
rior surgical optics with maximum brightness
and high contrast. The system is designed to
make this process easy for surgical staff and to
increase their comfort level as all filtering is built
into the system and is available whenever the
surgeon chooses to use ICG.
The ICG fluorescence sequence
is visualized through the microscope eyepieces,
on the video monitor, or both.
Leica DI C700
The Leica FL800 System
Leica M720
Leica M720 FL800 system
NIR optimized Dual Video Adapter
On/Off switch on
the surgical microscope joystick
Leica M525 OH4 FL800
The Best Possible Image
The Fluorescence Technique
To improve the visible image and near-infrared ICG signal,
Leica Microsystems has developed a NIR-optimized beam splitter
and Dual Video Adapter. The perfect matching of the illumination
and NIR video filters create a bright ICG fluorescence image. The
surgeon and operating room staff can view the image on a video
monitor and record it for later viewing.
The Leica Dual Imaging Color
Integrating the Leica DI C700 Dual Imaging Color Module with the
Leica M720 optics carrier (or Leica DI C500 with the Leica M525)
allows the surgeon to insert the image into the eyepiece, if de-
sired. The 1024 x 768 pixel resolution of the Leica DI C700/DI C500
gives the viewer 66% more pixels than competitive microscopes
and provides a bright, crisp, and true color image. This is critical
when viewing ICG fluorescence images.
Leica M720 OH5 FL800
OverHead Stands and Leica M-series Optics Carriers
The Leica FL800 ICG fluorescence module can be integrated
with the Leica M720 OH5, Leica M525 OH4, and Leica M520 OH3.
Leica Microsystems’ premium Leica M720 Apo- and Leica M525
OptiChrome
lution, and color fidelity. The ‘light touch’ maneuverability of the
Leica OH floorstands gives the surgeon perfect stability and func-
tionality for all vascular procedures.
TM
Optics offer outstanding contrast, sharpness, reso-
GA und Prospekt SOM
en_farbig 24.6.08
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