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Instructions for Use
1
HUMALOG®Mix75/25™ KwikPen
®
75% insulin lispro protamine suspension and
25% insulin lispro injection (rDNA origin)
Read the Instructions for Use before you start taking HUMALOG Mix75/25 and each
time you get a refill. There may be new information. This information does not take
the place of talking to your healthcare provider about your medical condition or your
treatment.
Do not share your HUMALOG Mix75/25 KwikPen with other people, even if
the needle has been changed. You may give other people a serious infection
or get a serious infection from them.
HUMALOG®Mix75/25™ KwikPen®(“Pen”) is a disposable pen containing 3 mL
(300 units) of U-100 HUMALOG®Mix75/25™ [75% insulin lispro protamine
suspension and 25% insulin lispro injection (rDNA origin)] insulin. You can inject
from 1 to 60 units in a single injection.
This Pen is not recommended for use by the blind or visually impaired
without the assistance of a person trained in the proper use of the product.
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Supplies you will need to give your HUMALOG Mix75/25 injection:
• HUMALOG Mix75/25 KwikPen
• HUMALOG Mix75/25 KwikPen compatible needle (Becton, Dickinson and
Company Pen Needles recommended)
• Alcohol swab
Preparing HUMALOG Mix75/25 KwikPen:
• Wash your hands with soap and water.
• Check the HUMALOG Mix75/25 KwikPen Label to make sure you are taking the
right type of insulin. This is especially important if you use more than 1 type of
insulin.
• Do not use HUMALOG Mix75/25 past the expiration date printed on the Label.
• Always use a new needle for each injection to help ensure sterility and
prevent blocked needles. Do not reuse or share your needles with
other people. You may give other people a serious infection or get a
serious infection from them.
2
Step 1:
Pull the Pen Cap straight off.
Wipe the Rubber Seal with an alcohol
swab.
• Do not twist the cap.
• Do not remove the KwikPen Label.
Step 2:
Gently roll the Pen ten times.
Invert the Pen ten times.
HUMALOG Mix75/25 should look white
and cloudy after mixing. Do not use if it
looks clear or contains any lumps or
particles.
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Step 3:
Pull off the Paper Tab from Outer Needle
Shield.
Step 4:
Push the capped Needle straight onto the
Pen and turn the Needle forward until it is
tight.
Step 5:
Pull off the Outer Needle Shield. Do not
throw it away.
Pull off the Inner Needle Shield and throw
it away.
3
Priming your HUMALOG Mix75/25 KwikPen:
Prime before each injection. Priming ensures the Pen is ready to dose and
removes air that may collect in the cartridge during normal use. If you do not prime
before each injection, you may get too much or too little insulin.
Step 6:
Turn the Dose Knob to select 2 units.
Step 7:
Hold your Pen with the Needle pointing
up. Tap the Cartridge Holder gently to
collect air bubbles at the top.