HP CFL-512 User Manual

Leycom® CFL-512 and Conduct NT

CD Leycom September 2004

The LEYCOM® Cardiac Function Lab CFL-512 facilitates the on-line
measurement and analysis of ventricular pressure and volume signals in clinical
setting. The pressure and volume signals are obtained using a combined
conductance and pressure catheter. The CFL-512 acquires and displays these
signals on-line and continuously. The signals are digitized, stored and can be
subsequently played back and analyzed the users convenience.

The Leycom

®

CFL-512 is a stand-alone device, which can be easily used in

different clinical environments. The system, including the software for data
acquisition and analysis, has been developed in close co-operation with a group
of clinical users of Leycom

The Leycom

®

CFL-512 consists of a bedside 'patient module' and a console.

®

equipment.

The bedside 'patient module' is a state of the art, battery powered, data
acquisition module. The module, to which the conductance catheter is
connected, contains sophisticated circuitry, which ensures optimal patient safety
and extended battery life.
The 'patient module' is communicates with the Leycom
a fibre optic cable; this provides complete patient isolation from electrical
hazard.

dedicated computer

The

is Intel Pentium based, has a 40 Gb harddisk, enough
for hundreds of hours of data acquisition, at 12 channels and 250 samples per
second.

With the Leycom

®

CFL-512 software, time-varying ventricular volume,

pressure, ECG, a large number of hemodynamic variables and Pressure-volume
loops can be displayed. The slope and intercept of the end-systolic pressure­volume relation (a measure of ventricular performance) are calculated, as well as
other related variables.

®

CFL-512 console via

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CFL-512

Conduct NT – for clinical evaluation only

Features

• Dyssynchrony calculation for each segment

• Many calculated indices, displayed in real time

• Operator independent parallel conductance calculation

• Ability to show calibrated data in real time

• Improved screen and reports printouts

• Analysis of large files

• Easier to 'grab' screens for presentations or publications

• Improved study management

• Extended patient data input screen

• Extended views

A Microsoft Windows based acquisition, display and analysis
program has been developed for the Leycom
Leycom
quantitative cardiac function assessment in humans.
The new program, Conduct NT, replaces and radically
improves upon the old DOS based 'Conduct 2000' for the
Leycom

®

CFL-512 is the clinically approved system for

®

CFL-512.

Usage in the clinical setting:

®

CFL-512. The

• The quantitative assessment of systolic and diastolic heart failure

• Determination of heart failure treatment strategy

• Calculation of ventricular mechanical dyssynchrony

• To guide pacing strategies

• Status assessment of congenital heart disease

• Evaluation of surgical procedures (DOR procedure, mitral valve repair)

• Monitoring critical patients peri-operatively

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CFL-512

Conduct NT – Analyse Recorded Data

Conductance Catheter Settings

Match the catheter with the actual heart size, exclude individual segments
and optimize the dual field setting.

Rho measurement

The Rho cuvette is used to measure blood resistivity from a blood sample. Blood
resistivity is required for the calibration of the volume measurements. The Rho
cuvette is connected to the connector on the right side of the CFL-512. When
the Rho cuvette is filled with 5 ml of blood the display will show the measured
blood resistivity. By pressing the button next to the display this value is stored
internally and used in the real-time volume calculation.

Calibration

Calibration of the volume signals from the conductance
catheter is automatic. However, the 6 user defined signals
connected to the external inputs, Pressure, ECG 2, Aux1,
Aux2, Aux3 and Aux4 require initial calibration to enable the
software to convert input signal voltages to user units (e.g.
mmHg).

Display

Select display-mode and time-base for an optimal view of your chosen signals.
View ‘Segmental Volumes’ to check and optimise the (segmental) volume
signals. Use views with ‘PV-Loop’ to monitor the pressure-volume loops from
beat to beat. Use views with ‘Indices’ to display real-time the calculated indices.
Use ‘Dyssynchrony’ view to assess mechanical ventricular dyssynchrony.

Acquire Data

Start data acquisition by clicking ‘Acquire’. An audible signal every 1 s
reminds the user that acquisition is in progress. Stop data acquisition by
clicking acquire again. Enter a comment at the end of each acquisition run.

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CFL-512

Conduct NT – Analyse Recorded Data

Select data file

Retrieve previously acquired data files for subsequent
analysis.
The comment and some file characteristics are displayed in
the list.

Pressure-volume analysis

The end-systolic and end-diastolic PV points are indicated with markers (blue
and green lines). Appropriate (user-selected) functions can be fitted through
these points taken and varying pressures and volumes to calculate contractility
and compliance.

Print Report

Create your own print reports with indices. Select the reports you want to print.

Use the short-cut button

to print the latest report.

Indices

Create your own indices-display by selecting the indices that are available in the
list. Conduct NT has more than 50 parameters in his list of indices.

Volume calibration

Vc calculation (parallel conductance)

Vc will be calculated automatically from the data acquired during a hypertonic
saline injection.

Alpha calculation

To correct the underestimation of true volume, the results measured by the
conductance catheter should be compared to the results of an independent
cardiac output measurement, thermodilution, echo or angiography for example.

Additional features in Conduct NT…..

• Interval measurement

• Several filters can be used

• Exporting data and indices to comma-separated file

• Beat to beat analysis

• Complete file management

• Signals can be individually scaled.

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u

CFL-512

Highlights

Hardware Software

Console

• Pentium, 1 GHz with 256 Mb RAM

• Dedicated hardware for:

Acquisition of external signals
Communication with patient module
Patient module battery management

• Monitor, NEC Multisync XP 1750

• Data storage, 40 GB harddisk

• 250 Mb Zip drive

• Laser printer, HP LaserJet 2100

• Drip-proof keyboard with trackball and two buttons

Patient module

• All settings are software controlled

• Catheter connector: 16 pole Binder

• Battery powered to ensure patient safety

• More than 180 min continuous use when fully

charged

• Communication with console via fiber optic cable

• AD conversion: 250 samples/sec, 12 bit

Patient safety

• Battery powered patient module

• Communication via fiber optic cable

• Inductive battery charger

Conduct NT

• Real-time display
various display modes
variable time-base

• Several filters

• Data acquisition

automatic file naming
attached comments
250 samples/sec, 12 bit accuracy
8 internal (patient module) and 6 external channels

• Calibration of external signals
conversion to user units
optimize resolution

• Display of acquired data

• Calculation of calibration factors for conductance-

volume

• Analysis of pressure-volume relations

• Calculation of hemodynamic indices

• Print/save graphs and own reports

• Printer settings

• Data export

CD Leycom

Argonstraat 116
2718 SP Zoetermeer
Tel. [phone]
Fax. [phone]
Email : [e-mail]
Website : www.cdleycom.com

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