Page 1
Fraction Collector Frac-920 and
Frac-950
Operating Instructions
Original instructions
Page 2
Table of Contents
31 Introduction ..........................................................................................................
41.1 Important user information .............................................................................................................
51.2 Regulatory information ......................................................................................................................
81.3 Instrument ...............................................................................................................................................
91.3.1 Fraction Collector Frac-920 .......................................................................................................
111.3.2 Fraction Collector Frac-950 .......................................................................................................
121.4 Control software ....................................................................................................................................
121.5 User documentation ...........................................................................................................................
142 Safety instructions ...............................................................................................
142.1 Safety precautions ...............................................................................................................................
192.2 Labels .........................................................................................................................................................
212.3 Emergency procedures ......................................................................................................................
222.4 Recycling information .........................................................................................................................
232.5 Declaration of Hazardous Substances (DoHS) ........................................................................
253 Installation ............................................................................................................
253.1 Site requirements ..................................................................................................................................
253.2 Transport ..................................................................................................................................................
263.3 Unpacking ................................................................................................................................................
263.4 Assembly ..................................................................................................................................................
263.5 Connections ............................................................................................................................................
273.6 Spare parts and accessories ...........................................................................................................
284 Operation ..............................................................................................................
284.1 Fraction Collector Frac-920 stand alone ...................................................................................
374.2 Fraction Collector Frac-920 connected to an ÄKTA instrument .....................................
394.3 Fraction Collector Frac-950 .............................................................................................................
475 Maintenance .........................................................................................................
475.1 General ......................................................................................................................................................
475.2 Cleaning ....................................................................................................................................................
485.3 Changing capillaries ............................................................................................................................
485.4 Changing waste tubing ......................................................................................................................
496 Troubleshooting ...................................................................................................
496.1 Faults and actions ................................................................................................................................
517 Reference information ........................................................................................
517.1 Specifications .........................................................................................................................................
527.2 Health and Safety Declaration Form ...........................................................................................
547.3 Ordering information ..........................................................................................................................
2 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
Table of Contents
Page 3
1 Introduction
Purpose of the Operating
Instructions
The Operating Instructions provide you with the instructions needed to handle Fraction
Collector Frac-920 and Frac-950 in a safe way.
Prerequisites
In order to operateFraction Collector Frac-920and Frac-950 asis intended, thefollowing
pre-requisites must be fulfilled:
•
The user should have a general understanding of how a PC and the Microsoft
®
Windows®operating system works. (if a computer is used)
•
The user must understand the concepts of liquid chromatography.
•
The user must read and understand the Safety Instructions in this manual.
•
Fraction CollectorFrac-920 and Frac-950 andsoftware shouldbe installed, configured
and calibrated according to these Operating Instructions.
About this chapter
This chapter contains important user information, a description of the intended use of
Fraction Collector Frac-920 and Frac-950, regulatory information, list of associated
documentation, definitions of safety notices and so on.
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 3
1 Introduction
Page 4
1.1 Important user information
Read this before operating the
product
All users must read the entire Operating Instructions before installing, operating or
maintaining the product.
Always keep the Operating Instructions at hand when operating the product.
Do not operate the product in any other way than described in the user documentation.
If you do, you may be exposed to hazards that can lead to personal injury and you may
cause damage to the equipment.
Intended use
Fraction Collector Frac-920 and Fraction Collector Frac-950 are automated fraction
collectors for use in ÄKTA™ chromatography systems. Fraction Collector Frac-920 can
also be used as a stand-alone unit.
Fraction Collector Frac-920 and Frac-950 are intended for research use only, and shall
not be used in any clinical procedures, or for diagnostic purposes.
Safety notices
This user documentation contains WARNINGS, CAUTIONS and NOTICES concerning the
safe use of the product. See definitions below.
Warnings
WARNING
WARNING indicates a hazardous situation which, if not avoided,
could result in deathor serious injury.It is important not toproceed
until all stated conditions are met and clearly understood.
4 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
1 Introduction
1.1 Important user information
Page 5
Cautions
CAUTION
CAUTION indicates a hazardous situation which, if not avoided,
could result in minor or moderate injury. It is important not to
proceed until all stated conditions aremet and clearlyunderstood.
Notices
NOTICE
NOTICE indicates instructions that must be followed to avoid
damage to the product or other equipment.
Notes and tips
A note is used to indicate information that is important for trouble-free and
optimal use of the product.
Note:
A tip contains useful information that can improve or optimize your procedures.
Tip:
Typographical conventions
Software items are identified in the text bybold italic text. A colonseparates menu levels,
thus File:Open refers to the Open command in the File menu.
Hardware items are identified in the text by bold text (e.g., Power switch).
1.2 Regulatory information
In this section
This sectiondescribes the directives and standards thatare fulfilled by Fraction Collector
Frac-920 and Frac-950.
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 5
1 Introduction
1.1 Important user information
Page 6
Manufacturing information
The table below summarizes the required manufacturing information. For further infor-
mation, see the EU Declaration of Conformity (DoC) document.
ContentRequirement
GE Healthcare Bio-Sciences AB,Name and address of manufacturer
Björkgatan 30, SE 751 84 Uppsala, Sweden
Conformity with EU Directives
This product complies with the European directives listed in the table, by fulfilling the
corresponding harmonized standards.
TitleDirective
Machinery Directive (MD)2006/42/EC
Electromagnetic Compatibility (EMC) Directive2004/108/EC
Low Voltage Directive (LVD)2006/95/EC
CE marking
The CE marking and the corresponding EU Declaration of Conformity is valid for the in-
strument when it is:
•
used as a stand-alone unit, or
•
connected to other products recommendedor describedin the user documentation,
and
•
used inthe same stateas it was delivered from GE Healthcare,except for alterations
described in the user documentation.
6 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
1 Introduction
1.2 Regulatory information
Page 7
International standards
This product fulfills the requirements of the following standards:
NotesDescriptionStandard
EN standard is harmonized
with EU directive
2006/95/EC
Safety requirements for electrical
equipment for measurement,
control, and laboratory use
EN/IEC 61010-1,
UL 61010-1,
CAN/CSA-C22.2
No. 61010-1
EN standard is harmonized
with EU directive
2004/108/EC
Electrical equipment formeasure-
ment, control and laboratory use
- EMC requirements
EN 61326-1
EN ISO standard is harmo-
nized with EU directive
2006/42/EC
Safety of machinery. General
principles for design. Risk assess-
ment and risk reduction.
EN ISO 12100
FCC compliance
This device complies with part 15 of the FCC Rules. Operation is subject to the following
two conditions: (1) This device may not cause harmful interference, and (2) this device
must accept anyinterference received, includinginterference that may cause undesired
operation.
The user is cautioned that any changes or modifications not expressly approved
by GE Healthcare could void the user’s authority to operate the equipment.
Note:
This equipment has been tested and found to comply with the limits for a Class B digital
device, pursuant to part 15 of the FCC Rules. These limits are designed to provide rea-
sonable protection against harmful interference in a residential installation. This equip-
ment generates, uses and can radiate radio frequency energy and, if not installed and
used in accordance with the instructions, may cause harmful interference to radio
communications. However, there is no guarantee that interference will not occur in a
particular installation. If this equipment does cause harmful interference to radio or
television reception, which can be determined by turning the equipment off and on, the
user is encouraged to try to correct the interference by one or more of the following
measures:
•
Reorient or relocate the receiving antenna.
•
Increase the separation between the equipment and receiver.
•
Connect the equipment into an outlet on a circuit different from that to which the
receiver is connected.
•
Consult the dealer or an experienced radio/TV technician for help.
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 7
1 Introduction
1.2 Regulatory information
Page 8
Regulatory compliance of
connected equipment
Any equipmentconnected to FractionCollector Frac-920 and Frac-950 shouldmeet the
safety requirements of EN 61010-1/IEC 61010-1, or relevant harmonized standards.
Within the EU, connected equipment must be CE marked.
Environmental conformity
This product conforms to the following environmental requirements.
TitleRequirement
Restriction of Hazardous Substances (RoHS) Directive2011/65/EU
Waste Electrical and Electronic Equipment (WEEE) Directive2012/19/EU
Administration on the Control of Pollution Caused by Electronic
Information Products, China Restriction of Hazardous Sub-
stances (RoHS)
ACPEIP
Registration, Evaluation, Authorization and restriction of
CHemicals (REACH)
Regulation (EC)
No 1907/2006
1.3 Instrument
Fraction Collector Frac-920 and Frac-950 are automated fraction collectors for use in
ÄKTA chromatography systems. Fraction CollectorFrac-920 can alsobe used as astand-
alone unit.
8 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
1 Introduction
1.2 Regulatory information
Page 9
1.3.1 Fraction Collector Frac-920
Main parts
1
2
3
4
5
6
7
8
Table 1.1: The main parts of Fraction Collector Frac-920.
DescriptionPart
Delivery arm1
Lock knob2
Control buttons3
Control buttons4
Collection tubes5
Tube rack6
Programming buttons7
Menu display8
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 9
1 Introduction
1.3 Instrument
1.3.1 Fraction Collector Frac-920
Page 10
Electrical and communication
connections
DescriptionPart
Drop sensor1
Valve2
Auxillary equipment3
Remote/digital I/O4
UniNet-15
Power inlet6
10 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
1 Introduction
1.3 Instrument
1.3.1 Fraction Collector Frac-920
Page 11
1.3.2 Fraction Collector Frac-950
Main parts
FRAC 950
FRAC 950
FRAC 950
FRAC 95
0
FRAC 950
Sta
ndar
d mode
Sta
ndar
d m
ode
1
2
3
4
5
1
2
3
4
5
1
2
3
4
5
Table 1.2: The main part of Fraction Collector Frac-950
DescriptionPart
Delivery arm1
Safety bar2
Collection tubes3
Tube rack4
Indicators5
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 11
1 Introduction
1.3 Instrument
1.3.2 Fraction Collector Frac-950
Page 12
Electrical and communication
connections
Voltage Frequency Power max.
100-120 / 50-60 Hz 300 VA
220-240 V~
Mains
RemoteDropSync
UniNet 3 UniNet 1
1
2 3
4
5
DescriptionPart
UniNet-3 connectors1
DropSync connector2
Power inlet3
Power switch4
UniNet-1 connector5
1.4 Control software
UNICORN™control software
UNICORN isa complete software for control and supervision of Fraction Collector Frac-920
and Frac-950. The software runs under Microsoft®Windows operating system.
For more information about UNICORN control system, see the UNICORN user manuals
supplied.
1.5 User documentation
In addition to these Operating Instructions, the documentation package supplied with
Fraction Collector Frac-920 and Frac-950 also includes product documentation binders
containing detailed specifications and traceability documents.
The mostimportant documents in thedocument package with regard totechnical aspects
of Fraction Collector Frac-920 and Frac-950 are:
12 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
1 Introduction
1.3 Instrument
1.3.2 Fraction Collector Frac-950
Page 13
System-specific documentation
ContentUser documentation
All instructions needed to operatethe instrument
in a safe way, including brief system description,
installation, and maintenance.
Fraction Collector Frac-920 and
Frac-950 Operating Instructions
Detailed system description. Comprehensive user
instructions, method creation, operation, ad-
vanced maintenance and troubleshooting.
Fraction Collector Frac-920 and
Frac-950 User Manuals
Document whereby the manufacturer ensures
that theproduct satisfies and is in conformity with
the essentialrequirements ofthe applicable direc-
tives.
EU Declarationof Conformity for
Fraction Collector Frac-920and
Frac-950
Software documentation
Together with each system,the following software documentation is supplied providing
additional informationthat applies to FractionCollector Frac-920 and Frac-950,indepen-
dent of the specific configuration:
Purpose/ContentsDocument
•
The manuals contain detailed instructions on
how toadminister UNICORN,work with methods,
perform runs and evaluate results.
•
The Online help contains dialog descriptions for
UNICORN. The Online help is accessed from the
Help menu.
UNICORN™ manual package
Component documentation
Documentation for components produced both by GE Healthcare and by a third-party
are, if existent, also included in the document package.
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 13
1 Introduction
1.5 User documentation
Page 14
2 Safety instructions
About this chapter
This chapter describes safety compliance, safety labels, general safety precautions,
emergency procedures, power failure and recycling of Fraction Collector Frac-920 and
Frac-950.
2.1 Safety precautions
Introduction
Fraction Collector Frac-920 and Frac-950 are powered by mains voltage and handles
liquids that may be hazardous. Before installing, operating or maintaining the system,
you must be aware of the hazards described in this manual. Follow the instructions
provided to avoid personal injury or damage to the equipment.
The safety precautions in this section are grouped into the following categories:
•
General precautions
•
Using flammable liquids
•
Personal protection
•
Installing and moving the instrument
•
System operation
•
Maintenance
General precautions
Always follow these General precautions to avoid injury when using Fraction Collector
Frac-920 and Frac-950.
WARNING
Do not operate Fraction Collector Frac-920 and Frac-950 in any
other way than described in the Fraction Collector Frac-920 and
Frac-950 Operating Instructions.
14 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
2 Safety instructions
Page 15
WARNING
Operation anduser maintenance of theFraction Collector Frac-920
and Frac-950 should be performed by properly trained personnel
only.
WARNING
Do not use any accessories not supplied or recommended by GE
Healthcare.
WARNING
Do not use the Fraction Collector Frac-920 and Frac-950 if it is not
working properly, nor if it has suffered any damage, for example:
•
damage to the power cord or its plug
•
damage caused by dropping the equipment
•
damage caused by splashing liquid onto it
WARNING
Operation and user maintenance of Fraction Collector Frac-920
and Frac-950 should be performed by properly trained personnel
only.
WARNING
Do not use the Fraction Collector Frac-950 if the safety bar is bro-
ken.
CAUTION
Waste tubesand containers must besecured and sealed toprevent
accidental spillage.
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 15
2 Safety instructions
2.1 Safety precautions
Page 16
CAUTION
Make sure waste container is dimensioned for maximum possible
volume when the equipment is left unattended.
NOTICE
Avoid condensation by letting the unit equilibrate to ambient tem-
perature.
Using flammable liquids
WARNING
A fume hood or similar ventilation system shall be installed when
flammable or noxious substances are used.
Personal protection
WARNING
Always use appropriate personal protective equipment during
operation and maintenance of Fraction Collector Frac-920 and
Frac-950.
WARNING
When using hazardous chemical and biological agents, take all
suitable protective measures, such as wearing protective glasses
and gloves resistant to the substances used. Follow local and/or
national regulations for safe operationand maintenance of Fraction
Collector Frac-920 and Frac-950.
16 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
2 Safety instructions
2.1 Safety precautions
Page 17
WARNING
Spread of biological agents. Theoperator has to takeall necessary
actions to avoid spreading hazardous biological agents in the
vicinity of the instrument. The facility should comply with the na-
tional code of practice for biosafety.
Installing and moving the
instrument
WARNING
Supply voltage. Make sure that the supply voltage at the wall
outlet corresponds to the marking on the equipment, before con-
necting the power cord.
WARNING
Fraction CollectorFrac-920 and Frac-950 mustalways be connect-
ed to a grounded power outlet.
WARNING
Power cord. Only use power cords with approved plugs delivered
or approved by GE Healthcare.
WARNING
Access to power switch and power cord with plug. Do not block
access to the power switch and power cord. The power switch
must always be easy to access. The power cord with plug must
always be easy to disconnect.
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 17
2 Safety instructions
2.1 Safety precautions
Page 18
NOTICE
Any computerused with the equipmentshall comply with IEC 60950
and beinstalled and used accordingto the manufacturer's instruc-
tions.
System operation
WARNING
Hazardous chemicals during run. When using hazardous chemi-
cals, run System CIP and Column CIP to flush the entire system
tubing with distilled water, before service and maintenance.
WARNING
Hazardous biological agents during run. When using hazardous
biological agents, run System CIP and Column CIP to flush the
entire system tubing with bacteriostatic solution (e.g. NaOH) fol-
lowed by a neutral buffer and finally distilled water, before service
and maintenance.
CAUTION
Pinch hazard. Do not have any part of your body within the unit
base area when Fraction Collector Frac-950 is switched on. An
automatic calibration process starts when Fraction Collector
Frac-950 is connected to UNICORN. During calibration, the dis-
penser arm moves rapidly. Several beeps are heard before the
calibration procedure starts.
CAUTION
Be sure to fold down the safety bar whenever the rack holder is
operated by hand. This blocks the rack holder from accidentally
moving while the rack is moved by hand or replaced. (Fraction
Collector Frac-950 only)
18 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
2 Safety instructions
2.1 Safety precautions
Page 19
Maintenance
WARNING
Electrical shock hazard. All repairs should be done by service
personnel authorized by GE Healthcare. Do not open any covers
or replace parts unless specifically stated in the user documenta-
tion.
WARNING
Disconnect power. Always disconnect power from theinstrument
before performing any maintenance task.
2.2 Labels
In this section
This sectiondescribes the instrument labelsand labels concerning hazardous substances
that are attached to the Fraction CollectorFrac-920 and Frac-950instrument. For infor-
mation about marking of the computer equipment, refer to the manufacturer’s instruc-
tions.
Labels on the instrument
The illustration below shows an example of the identification label that is attached to
Fraction Collector Frac-920 and Frac-950.
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 19
2 Safety instructions
2.1 Safety precautions
Page 20
Symbols used in instrument
labels
MeaningLabel
Warning! Read theuser documentation before using theequipment.
Do not open any covers or replace parts unless specifically stated in
the user documentation.
The equipment complies with the requirements for electromagnetic
compliance (EMC) in Australia and New Zealand.
The equipment complies with applicable European directives.
This symbol indicates that Fraction CollectorFrac-920 and Frac-950
has been certified by a Nationally Recognized Testing Laboratory
(NRTL). NRTL means an organization, which is recognized by the US
Occupational Safety and Health Administration (OSHA) as meeting
the legal requirements of Title 29 of the Code of Federal Regulations
(29 CFR), Part 1910.7.
Labels concerning hazardous
substances
MeaningLabel
This symbol indicates that the waste of electrical and electronic equip-
ment must not be disposed as unsorted municipal waste and must be
collected separately. Pleasecontact an authorized representative of the
manufacturer for information concerning the decommissioning of
equipment.
20 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
2 Safety instructions
2.2 Labels
Page 21
MeaningLabel
This symbol indicates that the product contains hazardous materials in
excess ofthe limits established bythe Chinese standard SJ/T11363-2006
Requirements for ConcentrationLimits for Certain Hazardous Substances
in Electronics.
2.3 Emergency procedures
In this section
This section describes how to do an emergency shutdown of the Fraction Collector
Frac-920 and Frac-950 system. The section also describes the result in the event of
power failure.
Emergency shutdown
In an emergency situation, do as follows to stop the run:
ActionStep
Press the Main power switch to the 0 position. The run is interrupted imme-
diately.
1
Power failure
The result of a power failure depends on which unit that is affected.
will result in...Power failure to...
•
The run is interrupted immediately, in an undefined state.
Fraction Collector
Frac-920 and
Frac-950
•
The UNICORN computer shuts down in an undefined state.
•
The data collected up to the time of the power failure is
available in UNICORN.
Computer
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 21
2 Safety instructions
2.2 Labels
Page 22
2.4 Recycling information
Decontamination
Fraction Collector Frac-920 and Frac-950 shall be decontaminated before decommis-
sioning and all local regulations shall be followed with regard to scrapping of the
equipment.
Disposal, general instructions
When taking Fraction Collector Frac-920 and Frac-950 out of service, the different ma-
terials must be separated and recycled according to national and local environmental
regulations.
Recycling of hazardous
substances
Fraction Collector Frac-920 and Frac-950 contains hazardous substances. Detailed in-
formation is available from your GE Healthcare representative.
Disposal of electrical
components
Waste ofelectrical and electronic equipment mustnot be disposedas unsorted municipal
waste and must be collected separately. Please contact an authorized representative
of the manufacturer for information concerning the decommissioning of equipment.
22 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
2 Safety instructions
2.4 Recycling information
Page 23
2.5 Declaration of Hazardous Substances (DoHS)
根据SJ/T11364-2006《电子信息产品污染控制标识要求》特提供如下有关污染 控制方面的信息。
The following product pollution control information is provided according to SJ/T11364-2006 Marking
for Control of Pollution caused by Electronic Information Products.
电子信息产品污染控制标志说明
Explanation of Pollution Control Label
该标志表明本产品含有超过SJ/T11363-2006《电子信息产品中有毒有害物质的限
量要求》中限量的有毒有害物质。标志中的数字为本产品的环保使用期，表明本
产品在正常使用的条件下，有毒有害物质不会发生外泄或突变，用户使用本产品
不会对环境造成严重污染或对其人身、财产造成严重损害的期限。单位为年。
为保证所申明的环保使用期限，应按产品手册中所规定的环境条件和方法进行正
常使用，并严格遵守产品维修手册中规定的期维修和保养要求。
产品中的消耗件和某些零部件可能有其单独的环保使用期限标志，并且其环保使
用期限有可能比整个产品本身的环保使用期限短。应到期按产品维修程序更换那
些消耗件和零部件，以保证所申明的整个产品的环保使用期限。
本产品在使用寿命结束时不可作为普通生活垃圾处理，应被单独收集妥善处理。
This symbolindicates the product contains hazardous materials inexcess of the limits
established by theChinese standard SJ/T11363-2006 Requirements for Concentration
Limits for Certain Hazardous Substances in Electronic Information Products. The
number in the symbol is the Environment-friendly Use Period (EFUP), which indicates
the period during which the toxic or hazardous substances or elements contained in
electronic information products will not leak or mutate under normal operating con-
ditions so that the use of such electronic information products will not result in any
severe environmental pollution, any bodily injury or damage to any assets. The unit
of the period is “Year”.
In order to maintain the declared EFUP, the product shall be operated normally ac-
cording to the instructions and environmental conditions as defined in the product
manual, and periodic maintenance schedules specified in Product Maintenance Pro-
cedures shall be followed strictly.
Consumables or certain parts may have their own label with an EFUP value less than
the product. Periodic replacement of those consumables or parts to maintain the
declared EFUP shallbe done in accordancewith the Product Maintenance Procedures.
This product must not be disposed of as unsorted municipal waste, and must be
collected separately and handled properly after decommissioning.
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 23
2 Safety instructions
2.5 Declaration of Hazardous Substances (DoHS)
Page 24
有毒有害物质或元素的名称及含量
Name and Concentration of Hazardous Substances
产品中有毒有害物质或元素的名称及含量
Table of Hazardous Substances’ Name and Concentration
有毒有害物质或元素
Hazardous substance
部件名称
Component name
多溴二苯醚
PBDE
多溴联苯
PBB
六价铬
Cr6+
镉
Cd
汞
Hg
铅
Pb
00000X18-1177-40
00000X18-6083-00
0:
表示该有毒有害物质在该部件所有均质材料中的含量均在SJ/T11363-2006 标准规定的限
量要 求以下
X:
表示该有毒有害物质至少在该部件的某一均质材料中的含量超出SJ/T11363-2006 标准规
定的限量要求
•
此表所列数据为发布时所能获得的最佳信息
0:
Indicates that this toxic or hazardous substance contained in all of the homogeneous ma-
terials for this part is below the limit requirement in SJ/T11363-2006.
X:
Indicates that this toxic or hazardous substance contained in at least one of the homoge-
neous materials used for this part is above the limit requirement in SJ/T11363-2006.
•
Data listed in the table represents best information available at the time of publication.
24 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
2 Safety instructions
2.5 Declaration of Hazardous Substances (DoHS)
Page 25
3 Installation
Fraction Collector Frac-920and Frac-950 is delivered in protective packing materialand
shall be unpacked with great care.
Any equipment connectedto Fraction Collector Frac-920 andFrac-950 must fulfill appli-
cable standards and local regulations.
For detailed information on Installation, see Fraction Collector Frac-920 and Frac-950
User Manuals.
3.1 Site requirements
RequirementParameter
Indoor useOperation site
Maximum 2000 mAltitude
100-240 V AC ±10%, 50-60 HzElectrical power
Overvoltage category IITransient overvoltages
4°C to 40°CAmbient temperature
Stable laboratory benchPlacement
20% to 95%, non-condensingHumidity
2Pollution degree
3.2 Transport
The equipment can be transported on a trolley capable of supporting at least 20 kg.
NOTICE
Always lift Fraction Collector Frac-920 and Frac-950 by the base
unit, never by the delivery arm, as this may damage the arm.
Before moving the system:
•
disconnect all cables and tubing connected to peripheral components and liquid
containers.
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 25
3 Installation
Page 26
•
lift the instrument by the base unit.
To make it easier to move Fraction Collector Frac-950 on the laboratory bench, first lift
the front (approx. 30°) and tilt the unit until the rubber feet clear the bench. Then move
the unit to the desired location.
3.3 Unpacking
Check for damage
Check the equipment for damage before starting assembly and installation. There are
no loose partsin the transport box.All parts are either mountedon thesystem or located
in the accessory kit box. If any damage is found, document the damage, and contact
your local GE Healthcare representative.
Unpack the system
Remove straps and packing material. Then set the equipment upright before starting
installation.
3.4 Assembly
The following parts must be added to the Fraction Collector Frac-920 and Frac-950 in-
strument before it can be used:
•
Tube rack
•
Collection tubes
•
Tubing
•
Waste tube
3.5 Connections
Communication
Make sure that UNICORN control software is installed on the computer.
Connect the Fraction Collector Frac-920 and Frac-950 according to the electrical
drawings in electrical and communication connections for Fraction Collector Frac-920
or electricaland communication connections forFraction Collector Frac-950, respectively.
26 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
3 Installation
3.2 Transport
Page 27
Flow path
Connect inlet and outlet tubing to the system. See Fraction Collector Frac-920 and
Frac-950 User Manuals.
Electrical power
Connect the power cord to a grounded power outlet specifiedin Section 3.1 Site require-
ments, on page 25
.
3.6 Spare parts and accessories
For correct up to date information on spare parts and accessories visit:
www.gelifesciences.com/AKTA
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 27
3 Installation
3.5 Connections
Page 28
4 Operation
About this chapter
This chapterprovides instructions for theuse of FractionCollector Frac-920 and Frac-950.
4.1 Fraction Collector Frac-920 stand alone
Starting the instrument
1
Connect the power cord to the mains power outlet. The display lights up and the
system immediately performs a self-test.
2
During the self-test, several messages are shown on thedisplay, forexample system
name and software version number, and a beep is heard. If an error is detected
during the self-test, an error message is shown.
3
The self-test takes about five seconds. When the start-up is completed, the display
shows the Run Method menu.
Menu display
See Fraction Collector Frac-920 for the layout of the Frac-920 front panel.
•
Press
or to select a specific menu.
•
Press OK to enter a sub menu.
•
Press Esc once to move back one menu level, or repeatedly to return to the main
menu level.
28 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
4 Operation
Page 29
The Fraction Collector Frac-920 software is divided into three main menus:
DescriptionMenu
Run Method is used for running methods that are pro-
grammed by the user. The Run Method menu is dis-
played after the self-test. See
Running a method, on
page 35
.
Program Method is used for creating new methods. To
reach the Program Method menu, press
. See Pro-
gramming a method, on page 31
.
Setup and Check is usedfor setup andchecking internal
system parameters, such as Fraction Base and Delay
UV to Frac. For more information, refer to Fraction col-
lector Frac-920 User Manual. To reach the Setup and
Check menu, press again.
Changing a parameter value
DescriptionNo.
Parameter1
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 29
4 Operation
4.1 Fraction Collector Frac-920 stand alone
Page 30
DescriptionNo.
Current value2
New value to be set3
To change a parameter value:
1
Press OK to enter the set value mode.
2
Press
or to change the set value. A cursor below a text or numerical value
shows what is affected when pressing the buttons.
3
Press OK to verify the set value and exit the set value mode. To cancel, press Esc.
Control buttons
DescriptionButton
Press feed tube to advance the fraction collector one position. The tube
feed is delayed according to the set value in the Set Delay UV to Frac
menu. Thecontrol button feed tube is disabled if connectedto CAN bus.
If the pump is off, the tube feed is done without a delay.
Press end to interrupt method operation before the method iscompleted.
Press pump on/off to start/stop thepump. When nomethod is running,
the pump can be used for e.g. buffer exchange or equilibration.
Press pause/cont. to pause all operation without ending the method.
All functions, including pump and fraction collector, are stopped. Press
pause/cont. again to restart the method operation.
30 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
4 Operation
4.1 Fraction Collector Frac-920 stand alone
Page 31
Programming a method
Under this menuyou can create up to 99different methods. In a methodyou can choose
e.g. fractionsize, and fractionstart and stop. When savinga method, it will be designated
a method number.
Before starting to create a method the method base should be checked (for
more information, refer to Fraction Collector Frac-920 User Manual).
Note:
Creating a new method
To create a new method:
1
From the Run Method menu, press
to reach the Program Method menu.
2
Press OK.
3
The number of free methods is displayed.
4
Select a free method and press OK.
Editing a method
To edit a method:
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 31
4 Operation
4.1 Fraction Collector Frac-920 stand alone
Page 32
1
Select a method number to edit. Press OK.
2
Select edit in the Method Occupied menu. Press OK.
It is only possible to change methods that have the same method base as the
one currently selected in Setup and Check.
Note:
Clearing a method
To clear a method (independent of method base):
1
Select a method number to clear. Press OK.
2
Select clear.
3
To confirm the deletion, select yes. Press OK.
Setting fraction parameters
When a new method is created or a current is edited, the first displayed menu will be
Set Fraction Size.
1
Press OK and select a fraction size using the arrow buttons.
2
Press OK.
3
To set fraction start, press
. Press OK.
4
Set a start value.
32 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
4 Operation
4.1 Fraction Collector Frac-920 stand alone
Page 33
5
Press OK.
Fraction start is used if you want to have a delay between the method
start and the start of collecting fractions. The pump is always started di-
rectly at method start.
Note:
6
To set a method end, press
. Press OK.
7
Set a method end value.
8
Press OK.
9
To activate the drop synchronization, press
. Press OK.
10
Select yes. To deactivate the function, select no. Press OK.
The flow rate should be < 5 ml/min to make drop synchronization possible.
Note:
Setting peak detection
The peak detecting function can be set to Off, Level or Slope.
To skip peak detection, press .
1
To activate a peak detecting function. Press OK.
2
Select Peak Detect: Level or Slope. Press OK.
•
If Levelhas been selected, setan absorbance level(% FSD) whento start collecting
fractions.
•
If Slope has been selected, set a slope (%/min).
•
Press OK.
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 33
4 Operation
4.1 Fraction Collector Frac-920 stand alone
Page 34
3
Set peak fraction size (ml).
4
Press OK.
For more information about the peak detection parameters, refer to Fraction Collector
Frac-920 User Manual.
Saving the method
1
Decide to save the method, select yes or no.
2
Press OK.
34 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
4 Operation
4.1 Fraction Collector Frac-920 stand alone
Page 35
Running a method
Used for running methods that are programmed by the user.
DescriptionNo.DescriptionNo.
Run menu 22Run menu 11
1
Use the Esc and arrow buttons to reach the Run Method menu.
2
Press OK.
3
Select which method to run.
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 35
4 Operation
4.1 Fraction Collector Frac-920 stand alone
Page 36
4
Press OK.
5
Press OK to start the run.
The status of the run is displayed. By using the arrow buttons, different statuses are
displayed.
Run menu 1
DescriptionNo.
Method no.1
Method status2
Method run length3
Tube no.4
Actual tube volume/fraction or peak fraction size. Tube volume is
counted from 0 to set value.
5
Run menu 2
DescriptionNo.
Flow (ml/min), if a valid pump is connected.1
36 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
4 Operation
4.1 Fraction Collector Frac-920 stand alone
Page 37
DescriptionNo.
Peak indication (Peak or No peak) is shown, if peak detect is turned
on (Slope or Level).
2
UV absorbance value (% FSD).3
Slope or level value (%/min or %).4
Fraction size, Method End and Peak detect can be changed during the run. To reach
the menus, use the arrow button. The changes of settings are the same as for program-
ming a method.
By settingthe value offraction size tozero, the SV-923 valve is set to waste (if connected).
Pause/cont. can be activated. Method End cannot be set to a value below actual value
of run method. The pump on/off button is not active during run.
4.2 Fraction Collector Frac-920 connected to an ÄKTA in-
strument
Fraction Collector Frac-920 is controlled from a PC running UNICORN version 3.0 or
higher. Control of Fraction Collector Frac-920 can be achieved automatically from a
preprepared method, or manually via the functions available in UNICORN.
Fraction Collector Frac-920 are designated “Frac-900” in UNICORN.
Note:
When Fraction Collector Frac-920 is controlled from UNICORN, all menu push
buttons are disabled.
Note:
The manual instructions in UNICORN allow the following operations:
•
Collecting a fixed volume in each tube.
•
Collecting each peak in a separate tube.
•
Feed tube – move on to next tube.
It is also possible to set the delay volume, which corresponds to the volume between
the UVmonitor and FractionCollector Frac-920. This valuemust be changedif the tubing
is changed to tubing of a different inner diameter, see
Setting the delay volume, on
page 39
.
Starting the instrument
1
Connect the power cord to the mains power outlet. The display lights up and the
system immediately performs a self-test.
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 37
4 Operation
4.1 Fraction Collector Frac-920 stand alone
Page 38
2
During the self-test, several messages are shown on thedisplay, forexample system
name and software version number, and a beep is heard.
If an error is detected during the self-test, an error message is shown.
3
The self-test takes about five seconds. When the self-test is completed, the display
shows the Run Method menu.
4
When UNICORN connects to Fraction Collector Frac-920, the displays shows the
message Uninet 1 connected for for a few seconds.
5
When connection is established, the message Setup and check is displayed.
Flow during tube change
The sampleflow during tube changecan be handledin two different ways. The selections
can be found under menu System Control:System: Settings:Specials.
1
To change the settings, select the instruction FracParameters.
2
For the parameter TubeChange select one of the following options:
•
Tube - No synchronization of collection.
•
DropSync - Tube change synchronized to drop release to minimise spillage.
Should only be used at flow rates below 5 ml/min.
3
Click on the Execute or OK button.
38 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
4 Operation
4.2 Fraction Collector Frac-920 connected to an ÄKTA instrument
Page 39
Setting the delay volume
The delay volume between the UV monitor and FractionCollector Frac-920 in your ÄKTA
chromatography system can be set. The fraction marks shown in UNICORN will be ad-
justed according to this volume to show the actual parts collected.
1
Select menu System Control:System: Settings:Specials in UNICORN.
2
To change the settings, select the instruction FracParameters.
3
Enter the new delay volume value. The appropriate value for your particular system
is found in the Reference information, a chapter in the System Manual of your ÄKTA
chromatography system. Refer also to the ÄKTA design Optional Configuration User
Manual.
4
Click onthe OK button. The value entered willbe used until a further change is made.
4.3 Fraction Collector Frac-950
CAUTION
Pinch hazard. Do not have any part of your body within the unit
base area when Fraction Collector Frac-950 is switched on. An
automatic calibration process starts when Fraction Collector
Frac-950 is connected to UNICORN. During calibration, the dis-
penser arm moves rapidly. Several beeps are heard before the
calibration procedure starts.
CAUTION
Be sure to fold down the safety bar whenever the rack holder is
operated by hand. This blocks the rack holder from accidentally
moving while the rack is moved by hand or replaced. (Fraction
Collector Frac-950 only)
NOTICE
The DropSync unit will be damaged if it is positioned below the
tube rims.
Turn on the Fraction Collector Frac-950 using the Power switch at the rear panel. The
Fraction Collector Frac-950 now performs a self-test.
There is one green and one yellow indicator on the front of Fraction Collector Frac-950.
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 39
4 Operation
4.2 Fraction Collector Frac-920 connected to an ÄKTA instrument
Page 40
The green indicator shows:
•
when flashing — power is on
•
when continuously lit — power is on and connection with UNICORN is established.
When lit, the yellow indicator shows that Fraction Collector Frac-950 is running.
When connected to UNICORN, several beeps are heard after which Fraction Collector
Frac-950 starts to perform an automatic calibration process. During this process, the
tube holder moves rapidly in several directions. When calibration is completed, the tube
holder stops in the home position.
The safety bar must be folded up for Fraction Collector Frac-950 to start up.
Note:
Operating Fraction Collector
Frac-950
Fraction Collector Frac-950 is controlled from a PC running UNICORN version 3.21 or
higher forstandard mode or version 4.0 orhigher for prep mode. ForÄKTAmicro, UNICORN
version 5.0 or higher is recommended. Control of Fraction Collector Frac-950 can be
achieved automatically from a method, or manually via the functions available in
UNICORN.
Using Fraction Collector Frac-950 in a method is described in the ÄKTA design Optional
Configuration User Manual.
The following functions are available for operating Fraction Collector Frac-950 from
UNICORN:
MethodManual
FractionationMan_Fractionation
Fractionation_StopFractionation_Stop
Feed_TubeFeed_Tube
Peak_FractionationMan_Peak_Fractionation
Peak_Frac_StopPeak_Frac_Stop
AccumulatorWashAccumulatorWash
-Ignore_LastTube
Reset_Frac_PositionReset_Frac_Position
(PeakFrac Parameters)(PeakFrac Parameters
40 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
4 Operation
4.3 Fraction Collector Frac-950
Page 41
DescriptionNo.DescriptionNo.
Select tube type and size3Select rack types1
Select tube type and size4Select fractionation order2
DescriptionNo.DescriptionNo.
Select fractionation bases2Select starting tubes1
It isalso possible toset the delayvolume, i.e., theadded volume of tubingand components
between the UV flow cell in the ÄKTA system and Fraction Collector Frac-950. This value
must be changed when the ÄKTA standard configuration system is changed to an op-
tional configuration.
Collecting fixed fractions
Details aboutcollecting fixed fraction volumesusing UNICORN in amethod are described
in the ÄKTA design Optional Configuration User Manual.
Collecting peak fractions
Details about collecting peaks only using Fraction Collector Frac-950 in a method are
described in the ÄKTA design Optional Configuration User Manual.
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 41
4 Operation
4.3 Fraction Collector Frac-950
Page 42
Feed tube
During fractionation, the tube rack can be moved forward one tube with the instruction
FeedTube.
1
Select menu System Control:Manual:Frac in UNICORN.
2
Select the instruction FeedTube in the Frac list.
3
Click on the Execute button. The tube rack moves on to the next tube after the set
delay volume has been collected.
Ignore_LastTube
The tube position in the rack which is defined in the start protocol to have the last tube
can be ignored with the instruction Ignore_LastTube.
When the last tube is reached and there are more fractions to collect, an alarm is gen-
erated andthe system ispaused. You can thenfill up with new tubes, and use the instruc-
tion Ignore_LastTube.
1
Select menu System Control:Manual:Frac in UNICORN.
2
Select the instruction Ignore_LastTube in the Frac list.
3
Click on the Execute button.
4
Fill up the rack with new tubes.
42 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
4 Operation
4.3 Fraction Collector Frac-950
Page 43
5
Click on the Continue button to restart the fractionation in the next tube.
Reset_Frac_Position
The instruction Reset_Frac_Position resets the fraction collector. This means that frac-
tionation set to start at next position will start in the first position. The instruction will
reset next position for all tube types.
1
Select menu System Control:Manual:Frac in UNICORN.
2
Select the instruction Reset_Frac_Position in the Frac list.
3
Click on the Execute button.
AccumulatorWash
The accumulator used to eliminate spillage at tube change can be manually washed
with the instruction AccumulatorWash.
1
Start a flow of 10 ml/min manually using the system pump.
2
If the fraction collector is connected to any other port than port 1 in the Outlet valve,
you must manually switch Outlet Valve to the other port. Select menu System Con-
trol:Manual:Flowpath in UNICORN.
3
Select the instruction OutletValve and select the desired port.
4
Click on the Execute button.
5
Select menu System Control:Manual:Frac in UNICORN.
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 43
4 Operation
4.3 Fraction Collector Frac-950
Page 44
6
Select the instruction AccumulatorWash in the Frac list.
7
Select the number of strokes to be used for washing with the parameter Strokes.
8
Click on the Execute button.
Setting delay volume
The delayvolume between theUV flow cellin the chromatographicsystem and Fraction
Collector Frac-950 must be known to UNICORN. The delay volume is used to adapt the
collected fractions to the event marks generated by UNICORN.
1
In UNICORN, select menu System Control:System:Settings
2
Click the Specialsradio buttonand select instruction FracParameters. TheDelayVol
instruction becomes highlighted.
3
To change the setting, click on the up and down arrows for the DelayVol parameter,
or type a new value directly in the parameter window.
4
The appropriate value for your ÄKTA system is found in the ÄKTA design Optional
Configuration User Manual.
5
Click onthe OK button. The value entered willbe used until a further change is made.
44 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
4 Operation
4.3 Fraction Collector Frac-950
Page 45
Flow control during tube change
The liquid flow during tube change can be handled in three different ways.
1
In UNICORN, select menu System Control:System:Settings.
2
Click theSpecials radio button and select instruction FracParameters. Highlight the
TubeChange instruction.
3
For the parameter TubeChange, select one of the following options:
•
Tube
No synchronization of collection. Spillage will occur between tubes.
•
DropSync
Tube change is synchronized to drop release to minimize spillage.
Use i.d. 0.75 mm tubing between the DropSync and the accumulator.
•
Accumulator
During tube change, the flow is diverted to the accumulator which stores the
liquid. When the new tube is in position, the liquid is pressed out rapidly for col-
lection.
4
Flow rate limit recommendations using DropSync without spillage are given in the
table below. For higher flow rates the accumulator is recommended for spillage free
fractionation. For the 30 mm rack and Prep mode racks the accumulator is recom-
mended.
Flow rate limit using dropSync
[ml/min]
Rack type
0 to 1.0microplates
0 to 1.512 mm
0 to 2.018 and 30 mm
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 45
4 Operation
4.3 Fraction Collector Frac-950
Page 46
5
After selection, click on the OK button.
Define rack and tube parameters
When running a method, the rack and tube parameters for the rack to be used must be
set. This is described in detail in the ÄKTA design Optional Configuration User Manual.
46 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
4 Operation
4.3 Fraction Collector Frac-950
Page 47
5 Maintenance
5.1 General
Fraction Collector Frac-920 and Frac-950 require no periodic maintenance.
5.2 Cleaning
WARNING
When using hazardous chemical and biological agents, take all
suitable protective measures, such as wearing protective glasses
and gloves resistant to the substances used. Follow local and/or
national regulations for safe operationand maintenance of Fraction
Collector Frac-920 and Frac-950.
The fraction collector should be kept clean and spilled liquid should be wiped off before
it dries. Remove dirt from the surface using a cloth and a mild cleaning agent.
The rack holder should be positioned over the centre.
The safety bar should be folded down when the fraction collector is not in use (Fraction
Collector Frac-950 only).
When your ÄKTA system is cleaned, also clean the capillaries and the accumulator in
Fraction Collector Frac-950 with distilled water.
The instrument should be wiped regularly with a damp cloth. Remember to wipe the
DropSync unit photocell as well. Allow the instrument to dry completely before use.
Cleaning before planned
maintenance/service
To ensure the protection and safety of service personnel, all equipment and work areas
must beclean and free of anyhazardous contaminants before a Service Engineerstarts
maintenance work.
Please complete the checklist in the On Site Service Health and Safety Declaration Form
or the Health and Safety Declaration Form for Product Return or Servicing, depending on
whether theinstrument is goingto be serviced on siteor returned for service, respectively.
Copy theform you need from
Section 7.2 Health and Safety Declaration Form, on page52
or print it from the PDF file available on the User Documentation CD.
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 47
5 Maintenance
Page 48
5.3 Changing capillaries
Change the capillaries when they show signs of leakage or wear (sharp bending, for
example).
5.4 Changing waste tubing
Change the waste tubing when it shows signs of wear.
48 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
5 Maintenance
5.3 Changing capillaries
Page 49
6 Troubleshooting
WARNING
Disconnect power. Always disconnect power from theinstrument
before performing any maintenance task.
WARNING
Do notopen the instrument. There areno user serviceable compo-
nents inside, and you can be exposed to high voltage.
CAUTION
Be sure to fold down the safety bar whenever the rack holder is
operated by hand. This blocks the rack holder from accidentally
moving while the rack is moved by hand or replaced. (Fraction
Collector Frac-950 only)
CAUTION
Only spare parts that are approved or supplied by GE Healthcare
may be used for maintaining or servicing the unit.
6.1 Faults and actions
ActionFault
•
Start a flow and start fractionation.
•
Select FeedTube from the menu SystemControl:Man-
ual:Flowpath. If the motor does not start and an error
appears, contact GE Healthcare.
•
Check the delay volume. A largedelay volume at a low
flow rate generates a long delay time.
No tube change
Faulty parameters in UNICORN may be the cause.Tubes skipped
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 49
6 Troubleshooting
Page 50
ActionFault
•
The drop sensor photocell is dirty. Clean the photocell
with a damp cloth.
•
Check that the capillary end projection is not too long
(~2 mm).
•
Check that the flow rate is not too high (a continuous
flow).
DropSync is not func-
tioning
Check that the safety bar is folded up.No fractionsare collect-
ed
•
Check that the DropSync unit is close enough over the
tubes.
•
Check thatthe rack iscorrectly fitted tothe rack holder.
•
Check that thecapillary end is cut cleanlyand straight.
•
Check that the correct rack type is selected.
Liquid missesthe tubes
50 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
6 Troubleshooting
6.1 Faults and actions
Page 51
7 Reference information
About this chapter
This chapter contains technical data, regulatory and other information.
7.1 Specifications
ValueParameter
IP21 (Frac-950)Ingression protection
IP22 (Frac-920)
100-240 V AC ±10%, 50 to 60 HzSupply voltage
300 VA (Frac-950)Power consumption
20 VA (Frac-920)
480 × 380 × 550 mm (Frac-950)Dimensions (H × W × D)
250 × 320 × 400 mm (Frac-920)
16.5 kg (Frac-950)Weight
4.5 kg (Frac-920)
4° to 40°CAmbient temperature
20% to 95% (non-condensing)Relative humidity tolerance
84 to 106 kPa (840 to 1060 mbar)Atmospheric pressure
73 dB AAcoustic noise level
Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 51
7 Reference information
Page 52
7.2 Health and Safety Declaration Form
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52 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
7 Reference information
7.2 Health and Safety Declaration Form
Page 53
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Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC 53
7 Reference information
7.2 Health and Safety Declaration Form
Page 54
7.3 Ordering information
For ordering information visit www.gelifesciences.com/AKTA.
54 Frac-920 and Frac-950 Operating Instructions 28-9622-09 AC
7 Reference information
7.3 Ordering information
Page 55
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