HAZARDOUS DECOMPOSITION PRODUCTS:
Halogens, halogen acids and possibly carbonyl halides.
HAZARDOUS POLYMERIZATION:
Will not occur.
11. TOXICOLOGICAL INFORMATION
IMMEDIATE (ACUTE) EFFECTS:
Difluoromethane: LC50 : Inhalation 4 hr. (rat) - > 520,000 ppm
Pentafluoroethane: Cardiac Sensitization threshold (dog) > 100,000 ppm
DELAYED (SUBCHRONIC AND CHRONIC) EFFECTS:
Teratology – negative
Subchronic inhalation (rat) NOEL – 50,000 ppm
REPEATED DOSE TOXICITY:
Lifetime inhalation exposure of male rats was associated with a small increase in salivary gland fibrosarcomas.
OTHER DATA:
Not active in four genetic studies
FURTHER INFORMATION:
Acute effects of rapid evaporation of the liquid may cause frostbite. Vapors are heavier than air and can displace
oxygen causing difficulty breathing or suffocation. May cause cardiac arrhythmia.
POTENTIAL HEALTH HAZARDS
SKIN: Irritation would result from a defatting action on tissue. Liquid contact could cause frostbite.
EYES: Liquid contact can cause severe irritation and frostbite. Mist may irritate.
INHALATION: R-410A is low in acute toxicity in animals. When oxygen levels in air are reduced to 12-14% by
displacement, symptoms of asphyxiation, loss of coordination, increased pulse rate and deeper
respiration will occur. At high levels, cardiac arrhythmia may occur.
INGESTION: Ingestion is unlikely because of the low boiling point of the material. Should it occur, discomfort in
the gastrointestinal tract from rapid evaporation of the material and consequent evolution of gas
would result. Some effects of inhalation and skin exposure would be expected.
DELAYED EFFECTS: None known.
Ingredients found on one of the OSHA designated carcinogen lists are listed below.
INGREDIENT NAME NTP STATUS IARC STATUS OSHA LIST
No ingredients listed in this section