Clean Air CLF 475, CLF 675, CLF 575 User Manual

Clean Air Techniek B.V.

User manual

English Version 5.0

Series CLF

Laminar crossflow-cabinet

Types:

CLF 475

CLF 575

CLF 675

Offers protection for product

Before using the cabinet, please read this manual carefully. The required instructions have to be carried out first.

Clean Air Techniek B.V. Kuipersweg 37 3449 JA Woerden The Netherlands Phone: +31 (0) 348 41 11 14 Fax: +31 (0) 348 42 26 84 E-mail: info@cleanair.eu Internet: www.cleanair.eu

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Preface

Clean Air provides a complete range Laminar Airflow Cabinets for handling of non-hazardous materials, which require a clean particle free environment. The cabinets offer the highest product protection. The horizontal airflow prevents contaminated outside air to enter the workstation's work area, ensuring product protection.

Its application is in the field of pharmaceutical industry, biotechnology, pharmacies, hospital and university laboratories as well as tissue culture and electronic laboratories.

The CLF is a high-quality product constructed with high-grade components and materials, with new techniques, such as:

 Microprocessor control with a LCD display for the interface with the user;  Automatic up speeding fan; when there is increasing resistance in the filter the necessary

airspeeds are maintained;

 Integrated drain on the backside of the working surface to prevent spilled liquids to leak in

to the HEPA filter;

 White laminated wooden or stainless steel (304) working surface;  All internal areas of the working space are in line with the effective HEPA filter area, to

obtain a laminar flow;

 Side windows of safety glass for a good overview.

Furthermore the CLF is a service friendly cabinet, produced in The Netherlands.

We thank you for buying this cabinet and wish you good times working with this cabinet.

Clean Air Techniek B.V.

Version table

Vers. 5.0 25-11-09 MPE Document structure updated

Version: Date: From serial

number:

By: Check: Change:

All rights reserved. Nothing from this edition may be copied, or used in an automated database, or made public, either electronic, mechanical, by photocopies, recordings, or in any manner, without preceding written permission of Clean Air Techniek B.V. This also counts for the accompanying figures and/or plans.

Clean Air Techniek B.V. is entitled to change parts on each desired moment, without preceding or direct notification of the customer. The content of this user manual can be changed without preceding warning as well. For information concerning maintenance activities or repairs which are not mentioned in the user manual, please contact the service organization.

This user manual has been put together with all possible care, but Clean Air Techniek B.V. cannot take the responsibility for possible mistakes in this user manual or for the consequences of it.

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Index

1 Introduction _______________________________________________ 6

1.1 CLF__________________________________________________________________6

2 Safety regulations ___________________________________________ 7

2.1 Use in conformity with regulations _________________________________________7

2.2 Modifications and changes to the cabinet____________________________________7

2.3 Authorized persons _____________________________________________________7

2.4 General safety aspects __________________________________________________8

2.5 Explanation user safety symbols ___________________________________________9

3 Cabinet __________________________________________________ 10

3.1 Assembly-instruction ___________________________________________________10

3.2 Transport instructions __________________________________________________11

3.3 Dismantling & Disposal _________________________________________________11

4 Product description _________________________________________ 12

4.1 Type plate ___________________________________________________________12

4.2 Front panel __________________________________________________________12

4.3 Worktop _____________________________________________________________13

4.4 Plenum-construction ___________________________________________________13

4.5 Crossflow filter________________________________________________________13

4.6 Pre-filter _____________________________________________________________13

4.7 Support frame (optional)________________________________________________13

4.8 Main power connection _________________________________________________14

4.9 Electronics ___________________________________________________________14

4.10 Operating panel _______________________________________________________15

4.11 FL-lighting ___________________________________________________________15

4.12 Fan _________________________________________________________________15

4.13 Optional features ______________________________________________________15

5 Control___________________________________________________ 18

5.1 Using the cabinet______________________________________________________18

5.2 Display interface ______________________________________________________18

5.3 Starting up the cabinet _________________________________________________19

5.4 Locking functions cabinet _______________________________________________20

5.5 Power save mode _____________________________________________________21

5.6 Turn off _____________________________________________________________21

5.7 Control UV (optional)___________________________________________________22

5.8 Control sockets (Optional)_______________________________________________22

5.9 Menu functions _______________________________________________________23

5.10 General Information ___________________________________________________23

5.11 Information status cabinet ______________________________________________32

5.12 Settings _____________________________________________________________35

6 Alarms ___________________________________________________ 38

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6.1 Flow alarms __________________________________________________________38

6.2 Other alarms _________________________________________________________39

7 Cleaning__________________________________________________ 41

7.1 Cleaning the installation ________________________________________________41

7.2 Cleaning the UV-light (optional) __________________________________________41

8 Small maintenance and testing ________________________________ 42

8.1 Periodic maintenance __________________________________________________42

8.2 Replacement of the pre-filter ____________________________________________42

8.3 Replacing the fluorescent-light (FL light) ___________________________________43

8.4 Service contact _______________________________________________________44

8.5 Service contract _______________________________________________________44

8.6 Testing ______________________________________________________________44

9 Technical specifications ______________________________________ 45

9.1 Physical surrounding ___________________________________________________45

9.2 General specifications __________________________________________________45

10 Trouble shooting ___________________________________________ 48

Appendix I: Support frame CLF ____________________________________ 49

Appendix II: Replacement of the HEPA-filters ________________________ 50

1.

When does a HEPA filter need to be replaced? ______________________________50

2.

replacing the HEPA-filter ________________________________________________50

Appendix III: Efficiency test of the HEPA-filters _______________________ 52

Requirements ______________________________________________________________52

Appendix IV Measuring method air velocities _________________________ 53

Air velocities crossflow _______________________________________________________53

Appendix V: Lay-out boards ______________________________________ 54

Appendix VI: Alarm-test procedure_________________________________ 55

Appendix VII: Stickers __________________________________________ 57

Appendix VIII: Information installed options _________________________ 58

Installed options microprocessor _______________________________________________58

Appendix IX: User code__________________________________________ 61

Activating the user code _____________________________________________________61 Changing the user code ______________________________________________________62

Appendix X: Required specifications ________________________________ 63

Overview of the required specifications__________________________________________63

Appendix XI: Recommended spare parts list _________________________ 64

Appendix XII: TUV Low Pressure Mercury Lamps (Optional) _____________ 65

Appendix XIII: Statement of the agreement for machines _______________ 66

Appendix XIV: Memo____________________________________________ 67

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Index________________________________________________________ 68

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1 Introduction

1.1 CLF

The laminar crossflow-cabinet CLF has as purpose that the working surface is kept clear of particles by means of a clean laminar crossflow of air. By applying a HEPA-filter (High Efficiency Particulate Air) it is possible to work in this cabinet under conditions which are sterile, dust-free, or aseptic. The cabinet, therefore, offers a product protection.

Short description of the CLF

• At the top of the cabinet the inflow air is drawn through a pre-filter by a fan.

• This fan blows the air in the correct proportion to the crossflow HEPA-filter. Because the crossflow air passed through a HEPA-filter (High Efficiency Particulate Air), the working surface is free of particles.

• The airflow in the workspace is crosswards, thus preventing background air to flow into the class A workspace.

• The air flow leaves the cabinet by the work opening.

Figure 1: Sectional view CLF

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2 Safety regulations

ATTENTION!

Before starting service with the cabinet always ask the responsible person if there is no danger for the service engineer, labor personnel, the laboratory and the surrounding of the cabinet.

2.1 Use in conformity with regulations

Personnel that is not properly informed about the safety regulation and/or does not meet the requirements mentioned in

§2.3

Authorized persons

on page 7

, is not allowed to use the cabinet.

Improper use of the cabinet is not allowed.

2.2 Modifications and changes to the cabinet

In order to operate the cabinet safely changes and/or alterations shall only be made by Clean Air Techniek B.V., or shall be made after consultation with and permission in writing from Clean Air Techniek B.V. If modifications and changes are made on own initiative, without permission from Clean Air Techniek B.V., the parts of the cabinet concerned are no longer covered by the warranty. Clean Air Techniek B.V. cannot be held liable for the consequences of the modifications and the dangers, which might possibly occur as a result. The modifications mentioned here include the connection of the cabinet to an exhaust system.

2.3 Authorized persons

Operating the cabinet

The cabinet shall only be used by personnel which:

 is familiar with the content, regulations and warnings which are mentioned in the user manual;  is familiar with how to operate the cabinet;  is familiar with the start up procedure, the stop procedure and knows how to react in case of

emergency;

 is familiar with the regulations to keep the safety in all circumstances;  is capable to end a disturbance.

Maintenance and repairs general

Maintenance shall only be performed by qualified service engineers, who are sufficiently trained by Clean Air Techniek B.V. to:

 Estimate and avoid the dangers of the cabinet;  Estimate the consequences of their actions.  Before starting maintenance to the cabinet (mechanical and/or electric) disconnect the power

supply. Pay attention to rotating parts, after switching off the cabinet the fans will still rotate for a while.

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Maintenance and repair of the electrical cabinet

Maintenance shall only be performed by professional electro-technical service engineers, who are sufficiently trained by Clean Air Techniek B.V. when:

 They can estimate and avoid the dangers of the cabinet;  They can estimate the consequences of their actions;  They are sufficiently informed about the operation of the cabinet and the operation of the sub-

systems.

2.4 General safety aspects

1. The cabinet shall never be used unless the fan is switched into work mode and there is no alarm.

2. When the cabinet is not used, the cabinet should be switched in to power-save mode or closed/covered, to prevent that dust particles etc. from the room can get into the cabinet.

3. Always try to limit the amount of equipment in the workroom. Each object in the workroom will disturb the pattern of the airflow and a large number of equipment may lead to serious disruptions.

4. It’s is important that the cabinets will be kept clean. Even the smallest contamination which is not visible will be easily forgotten. It is important to clean often the working area, especially the work top.

5. Be careful with flammable liquids such as alcohol. The airflow is in the direction of the person, so be very careful, or even better; prevent to use this kind of liquids.

6. The use of hand gloves and over sleeves is recommended.

7. Always use a chair with the correct height.

8. Transport and installation of the cabinet is only allowed for authorized staff. Please contact the manufacturer or the seller of the products

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2.5 Explanation user safety symbols

GENERAL DANGER

You can harm yourself and others seriously if you do not follow the procedures carefully

HIGH VOLTAGE

DANGER OF EXPLOSION

DANGER BY INDUSTRIAL VEHICLE

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3 Cabinet

GENERAL DANGER

Be careful: high centre of gravity, crossover point.

The cabinet must be installed in a safe way. Clean Air Techniek B.V. supplies an optional support frame, which is designed for this purpose. When the cabinet is purchased without a support frame, it is advised to discuss the installation with the supplier.

3.1 Assembly-instruction

The cabinet has to be placed on the support frame recommended by the supplier. The assembly needs to be done as specified in instruction underneath.

Assembly support frame (Optional)

Build the support frame (see also

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Appendix I: Support frame CLF on page 49 for an explaining drawing):

• Mount the support yokes (Pos. 5) to the reinforcement plate (Pos. 6);

• Mount the feet support (Pos. 7);

• Position the covers (Pos. 4) and adjusting feet (Pos. 3).

Placing the cabinet

• Place the cabinet right on the forks of a forklift truck or lifting platform;

DANGER BY INDUSTRIAL VEHICLE

Be careful: Make sure the cabinet cannot slide from the forks.

• Move the cabinet to the correct height and position, perform this action as precise as possible above the support frame;

• The weight must be equally divided between the both forks and the cabinet must be horizontal levelled;

• The cabinet should be aligned with the support frame.

• Mount the cabinet to the support frame by means of the screws.

• Connect the powerplug to a grounded socket that is easy accessible.

In case of maintenance the cabinet must be completely free of voltage. This means that the connector in the socket must be easy to reach, otherwise a main-switch must be mounted between the cabinet and the power supply so that the cabinet can be cut off of the power-circuit.

3.2 Transport instructions

Before moving the cabinet make sure the power cable is disconnected of the power supply The cabinet must be transported on a strong solid pallet. After every transport the cabinet must be tested and calibrated.

GENERAL DANGER

Be careful: High center of gravity, crossover point.

3.3 Dismantling & Disposal

For dismantling and disposal follow the next instructions:

• See

§7.1 Cleaning the installation on page 41;

• See

§8.2 Replacement of the pre-filter on page 42

;

•

See

Appendix II: Replacement of the HEPA-filters

on page 50;

• Break the unit down into its component parts. You can re-cycle these components parts, dispose of them in accordance with local requirements.

For advice or information about dismantling or disposal please contact Clean Air Techniek B.V.

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4 Product description

Figure 2 Sectional view CLF

Partlist:

1. Pre-filter

2. Fan

3. Plenum-construction

4. Front panel + control panel + I/O board

5. HEPA-filter

6. Lighting

7. Worktop

4.1 Type plate

On type plate (right upper side) there are instructions that are important for the connection of the cabinet.

4.2 Front panel

Behind the front panel (Figure 2, Pos 4) a number of electrical components are mounted.

 Operating panel / operating board  Interface board, including fan control

To check one of these components, you need to open the front panel.

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4.3 Worktop

The workroom contains a white laminated wooden or stainless steel (304) worktop (Figure 2, Pos

7).

4.4 Plenum-construction

The plenum-construction (Figure 2, Pos 3) equalizes the air trough the crossflow filter.

4.5 Crossflow filter

The crossflow HEPA-filter* (Figure 2, Pos 5) has a very high efficiency: Class H14 in accordance with EN1822. After assembling, each filter will be tested separately. Through the service panel on the back the crossflow filter can be reached.

*) High Efficiency Particulate Air filter

4.6 Pre-filter

The pre-filter (Figure 2, Pos 1) is a filter in the class G3 accordance with EN779. Furthermore the pre-filter will enhance the life span of the HEPA-filter significantly.

4.7 Support frame (optional)

For a stable positioning of the cabinet we recommend the use of a support frame. For a good ergonomic work position the use foot support is present. In addition, it is recommended to use an in height adjustable, well disinfectable, chair to optimize the work position. See

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Appendix I: Support frame CLF on page 49.

4.8 Main power connection

The main power connection is positioned on the top of the cabinet. The power cable length is maximum 3 meters and should always be accessible. See technical specifications for details.

4.9 Electronics

The electronics (Figure 2, Pos 4) consists of:

• Operational print; positioned in the top hood behind the front panel;

• Control print, positioned behind the front panel, including:

o Fuse holders (see §9.2 on page 46 for fuse-numbers). o Fan control. The control is free adjustable in the range between 0% and 100% o An Air velocity compensating microprocessor regulates the fan speed to compensate

for main power fluctuations and filter pollution.

o Independent potential free output contact (interface board connector J6).

See Interface board on page 54.

o Main filter o Light ballast + starter for UV (Option) o Light ballast for FL-light

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4.10 Operating panel

Figure 3: Operating panel

The operating panel (Figure 3, Figure 2, Pos 4) consist of:

1- Display; 2- Function keys (4x); 3- Fixed keys (4x); 4- Signals.

4.11 FL-lighting

The Fluorescent-Lighting (Figure 2, Pos 6) is mounted in the Light unit.

HIGH VOLTAGE

4.12 Fan

The electric driven double suction fan (Figure 2, Pos 2) is maintenance-free.

4.13 Optional features

Gas connection

This connection is assembled together with a gas tap. Normally, both the inlet and outlet gas connections are hose connections, suitable for hoses with an inner diameter of 10 mm. All connections on the gas supply have to be done with a certified gas hose. After the connection on the gas supply, the gas connections have to be tested on leakage by a certified installer.

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Positions of the supply connection

• The connection, that is located inside the installation, is standard assembled on the worksurface inside the work space of the cabinet.

• The connection, that is located outside the installation, is standard assembled in the bottom of the installation.

Bunsen burner

Recommended to apply is the Fuego Bunsen burner, available at Clean Air Techniek B.V.

Positions of the supply connection

• The connection is standard through the workopening.

Vacuum/ O2/ N2 and compressed air connections

These connections are always assembled in combination with a tap.

Positions of the supply connection

• The connection, that is located inside the installation, is standard assembled in combination with a tap in the worksurface.

• The connection, that is located outside the installation, is standard assembled in the bottom of the installation.

UV-Radiator

The UV radiator is meant for disinfecting the working surface of the cabinet.

When the UV-radiator is on, the TL lighting will be switched off. The UV radiator may only be switched on when the work space of the cabinet is entirely closed, this makes sure that the user will not get in contact with UV-C radiation. Block the front aperture (a special night door can be ordered for this purpose).

DANGER FOR BURNING

Avoid direct contact with UV-C radiation. This causes burns to the skin and eyes.

The UV light can be switched on and off on the display

(see §5.7 on page 22). It is also possible to adjust the UV disinfection, for each day a certain disinfection period can be defined (see §5.10 on page 24).

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Watch Out!

Do not touch the UV-lamp with the hand and keep the lamp fat free; otherwise the lifetime will decrease. The UV-light must be cleaned with alcohol (70%) regularly (switch off the installation ). See §7.2 on page 41.

When the UV is switched on, the UV hour counter counts the lighting period. UV-lamps have, depending on fabricate and type, a limit in effective running hours. Replace the lamp frequently. For more info see Appendix XII: TUV Low Pressure Mercury Lamps (Optional) on page 65.

Sockets

The sockets are mounted in the working area. They can be operated at the control panel. See “Technical specifications”on page 45 for electrical details.

Alternative Options

Please contact Clean Air Techniek B.V. for information about alternative options.

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5 Control

5.1 Using the cabinet

Check if the information on the type plate is corresponding to the main power connection. Connect the cabinet to the main connection by putting the plug into a grounded socket that is easy accessible.

5.2 Display interface

Figure 4 Display Interface

The operating panel (

Figure 3

and

Figure 4

) consists of:

1. Display;

2. Function keys (4x);

3. Fixed keys (4x);

4. Signals.

Display:

The display has 4 lines, the lowest line gives the description of the function key underneath.

I

II

III

IV

Cabinet switched off – not safe

Monday 11:06:33

MENU

Socket=Off

Fixed keys:

Lighting ON/OFF

Work mode fan ON/OFF

Power save mode fan ON/OFF

Acknowledge / Enter

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Function keys:

The function of keys 1, 2, 3 and 4 is variable. In the last line of the display the function is shown.

Signals:

Alarm: Confirmed alarm state Alarm, flashing (along with acoustic signal): Actual alarm UV: Indication UV-light switched on OK: Safe user mode

All equipment and, if possible, all materials required for working with the cabinet need to be placed into the installation before starting up the cabinet. High equipment or objects can be placed in the working space by sliding or hinging the window upwards. Be careful: keep the safety regulations in consideration.

5.3 Starting up the cabinet

1

The lighting of the display will light up. The alarm indicator light is red

.

• Connect the power cable.

Cabinet switched off – not safe

Monday 11:06:33

MENU

Socket=Off

2

The fan starts. Cabinet is in start up mode.

The alarm indicator light is red

.

There is an acoustic alarm.

• Push button .

• To acknowledge this alarm, push button

.

Starting to work mode – not safe

Monday 11:06:33

MENU

Socket=Off

3

If the cabinet is secured with a user code, this code has to be entered first. The default code is 0001.

The user code can be changed by the user, see Appendix IX: User code on page 62.

• Enter actual user code.

• Confirm the code with button .

User code: 0000 (Enter code) A = Enter

>>

+

-

Esc

4

The light will switch on.

• Push button .

5

When the fan has reached the right airspeed, the alarm indicator will disappear. The following display will be shown.

However, the cabinet must operate for minimally 15 minutes more, before the cabinet is ready to work with.

Cabinet in work mode – safe

Monday 11:06:33

MENU

Socket=Off

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6

If the air speeds still are not right, the alarm will sound again. To see what is wrong:

See § 5.11 on page 32 for more info about this menu.

• Push button

(Menu).

• Push button

(B).

• Push button

.

• Back to starting menu: button

(Esc).

Starting to work mode – not safe

Monday 11:06:33

MENU

Socket=Off

A => Hour counter information B => Status cabinet C => Settings

A

B

C

Esc

Information Status Cabinet

A = Enter

=>

<=

Esc

Cabinet: Work mode Airflow 0.36 < < 0.54 m/s

=>

<=

Esc

5.4 Locking functions cabinet

(Only when the locking function is activated)

1

The cabinet will lock its functions after being 5 minutes in work position.

When, within these 5 minutes, an arbitrary button is pushed (e.g. lighting) the timer starts counting again.

2

From this moment the fanbuttons are not available anymore. The user code has to be entered to make the functions available again.

See Appendix IX: User code on page 62.

Cabinet in work mode - Safe Monday 11:06:33 Cabinet is locked with pincode

MENU

Socket=Off

3

If the cabinet has to be locked immediately after entering the code:

• Push button

for 5 seconds After 3 seconds, two short beeps will be heard as an acknowledgement the cabinet has been locked.

4

To unlock the cabinet, the user code has to be entered again.

See Appendix IX: User code on page 62

.

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5.5 Power save mode

When not using the cabinet for a short period of time, put it in the power save mode. The fan will run at half speed to save energy (synonyms for power save mode are standby mode or night mode).

1

Power save mode

The fan runs at half speed. There is an acoustic alarm.

• Push button

.

When the cabinet is locked enter the user code.

• To acknowledge this alarm push button .

Cabinet in power save mode – not safe

Airflow to low

MENU

Socket=Off

2

Switch off procedure

• With the next push on the power save button the

cabinet enters the switch off procedure.

Cabinet switched off – Not Safe

Monday 11:06:33

MENU

Socket=Off

3

Work mode

• Push button

.

Cabinet in work mode - Safe Monday 11:06:33

MENU

Socket=Off

5.6 Turn off

Remove all materials en accessories from the working area. Remove all spilled liquids and other parts in a responsible manner, according to the regulations.

1

The display will ask for the user code (only when the user code is activated).

• Push button

to turn off the cabinet.

2

The fan will be switched off.

• Enter the user code and push button

.

Cabinet switched off – Not Safe

Monday 11:06:33

MENU

Socket=Off

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5.7 Control UV (optional)

The UV-function is only visible if this option is installed. If not installed the function at the display is invisible. The UV-function may only be switched on with a completely closed workspace. See UV-Radiator on page 16) This prevents direct contact on the skin or eyes of the personnel.

Switching UV on

1

Make sure that the entire workspace is closed. Cabinet must be switched off or in power safe mode. The display shows “UV=Off”.

2

The UV will switch on. The display shows “UV=On”.

• Push button

(UV=Off).

Cabinet switched off – Not Safe

UV switched on

MENU

Socket=Off

UV=On

Switching UV off

3

The UV will switch off. The display shows “UV=Off”.

• Push button (UV=On).

Cabinet switched off – Not Safe

UV switched off

MENU

Socket=Off

UV=Off

FL (Fluoresced lamp)-Lighting and UV cannot be switched on both at the same time. As a safety precaution, one of them will automatically switch off.

5.8 Control sockets (Optional)

The sockets can always be switched on and off. If the cabinet is switched off, the sockets are automatically switched off. Also if the cabinet is switched from work mode into power save mode, the sockets are automatically switched off. See technical specification (see

§9.2 General specifications on page 45

) for maximum voltage and

current (fuses).

Switching socket on

1

Cabinet in work mode. See

§5.3 Starting up the cabinet

on page 19.

Cabinet in work mode - Safe Monday 11:06:33

MENU

Socket=Off

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2

The display shows: Socket=On. Power of socket is switched on.

• Push button (Socket=Off).

Cabinet in work mode - Safe Monday 11:06:33

Socket switched on

MENU

Socket=On

Switching socket off

3

The display shows: Socket=Off. Power of socket is switched off.

• Push button

(Socket=On).

Cabinet in work mode - Safe Monday 11:06:33

Socket switched off

MENU

Socket=Off

5.9 Menu functions

From the main menu you can go to: § 5.10 General information, § 5.11 Information about the status of the cabinet and § 5.12 information about the settings.

5.10 General Information

In general information more details are given about:

• Hour counter information and reset (FL, UV, Timer)

• Set up 7 days clock UV

• Set up socket 7 days clock

• Set up cabinet 7 days clock

• Set Actual time

Hour counter information and reset (FL, UV, Timer)

1

Cabinet in work mode. See

§5.3 Starting up the cabinet

on page 19.

• Push button (Menu).

Cabinet in work mode - Safe Monday 11:06:33

MENU

Socket=Off

2

• Push button

(A).

A => Hour counter information B => Status cabinet C => Settings

A

B

C

Esc

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3

Hour counter display shows.

Hour counter information

A = Enter

=>

<=

Esc

4

Hour counter information shows.

• Push button

.

*FL= Fluoresced lamp

Cabinet in use: 0:33 A: FL in use: 0:22 B: UV in use: 0:00

=>

Reset A

Reset B

Esc

There are three different possibilities, see 5a, 5b and 5c.

5a

Reset all timer and clock adjustments?

• Push button

(=>).

• Push button

(Reset).

• Push 2x button (Esc) for starting menu.

Reset hour counter and clock

=>

Reset

Esc

5b

Reset FL counter?

• Push button (reset A).

• Push button (Reset).

• Push 2x button

(Esc) for starting menu.

5c

Reset UV counter?

• Push button (reset B).

• Push button (Reset).

• Push 2x button (Esc) for starting menu.

Set up 7 days clock UV

1

Cabinet in work mode. See

§5.3 Starting up the cabinet

on page 19.

• Push button

(Menu).

Cabinet in work mode - Safe Monday 11:06:33

MENU

Socket=Off

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Set up for 7 days clock UV shows.

• Push button (A).

• Push button (=>).

• Push button .

A => Hour counter information B => Status cabinet C => Settings

A

B

C

Esc

Hour counter information

A = Enter

=>

<=

Esc

Set up for 7 days clock

A = Enter

=>

<=

Esc

UV-Function: Disabled

Timer

Clock

Disable

Esc

There are three ways to set the

UV:

- 2a. Timer

- 2b. 7 days clock

- 2c. Disable

Timer

2a

The timer sets a period until the UV turns off.

• Push button

(Timer), to set up the timer.

• Push button (Change), to change the time.

• The value can be changed by pushing button

(>>), (+) or (-).

• Acknowledge the setting with button

.

• Push 2x button

(Esc) for starting menu.

Clock (7 days clock)

2b

With the clock function, for each day of the week, you can set a variable period for the UV to be switched on. Keep in mind, you have to set the starting hour and starting minute for each day separately! For detailed information regarding programming this menu, see

• Push button (Clock), to set up the 7 days clock.

• Push button (Change), to change starting time en

ending time.

• The value can be changed by pushing button

(>>),

(+) or (-).

• Acknowledge the setting with button

.

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§5.9 Set up 7 days clock UV on page 24

.

• Push 2x button (Esc) for starting menu.

See also the

Example for programming the UV-lamp on page 26.

The timer function needs to be activated first, otherwise the sockets will not switch on.

Set up cabinet 7 days clock

With this menu it is possible to program an automatic switch action on of the cabinet. It is however not possible to switch off the cabinet itself automatically!

1

Cabinet in work mode. See

§5.3 Starting up the

cabinet on page 19.

• Push 5x button (1x Menu, 1 x A and 3x =>),

• Acknowledge the setting with button

.

Cabinet in work mode - Safe Monday 11:06:33

MENU

Socket=Off

Setting cabinet 7 days clock Function: disabled A = Enter

=>

<=

Esc

Tuesday Cabinet to work mode at 0.00

Disable

Change

Esc

2

Disable

• Push button

(Disable), to reset all previous

settings.

3

Change days:

• Push button

(Change), to change the day.

• The value can be changed by pushing,

(+) or

(-).

Tuesday Change day Cabinet to work mode at 0.00 A = Enter

>>

+

-

Esc

4

Change hours:

• Push button

(>>) to change the time.

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• The value can be changed by pushing button (+)

or

(-).

Change hours Cabinet to work mode at 10.00 A = Enter

>>

+

-

Esc

5

Change minutes:

• Push button (=>) again, to change the minutes.

• The value can be changed by pushing button

(+)

or

(-).

Thursday Cabinet to work mode at 10.00

=>

+

-

Esc

Change minutes Cabinet to work mode at 10.30 A = Enter

>>

+

-

Esc

6

Acknowledge the setting.

•

Acknowledge the setting with button .

•

Push 2x button (Esc) for starting menu.

For more days / hours / minutes, walk again through the menu and confirm each time.

Set up actual time

1

Cabinet in work mode. See

§5.3 Starting up the cabinet

on page 19.

Cabinet in work mode - Safe Monday 11:06:33

MENU

Socket=Off

2

Set up actual time:

Set up display the actual day shows.

• Push 6x button

(1x Menu, 1 x A and 4x =>).

• Acknowledge the setting with button

.

• Push button

(=>).

Set up actual time Monday 11:06:33 A = Enter

=>

+

-

Esc

Set up actual time change day Monday 11:06:33 A = Enter

>>

+

-

Esc

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• The day can be changed by pushing button (+) or

(-).

3

Change hours/min/sec:

Set up display set up the actual time shows.

• Push button

(>>) again.

• The hours/min/sec can be changed by pushing button

(+) or (-).

4

Acknowledge the settings

• Acknowledge the setting with button .

• Push 2x button

(Esc) for starting menu. Actual time appears when there are no more alarms. In case of power failure, actual time is kept in memory for one month.

5.11 Information status cabinet

In this menu the settings of the cabinet can be checked to inform service personnel. In information status more details are given about:

• Actual velocities, alarm setting and fan settings

• Information about the installed options (Sockets, UV)

• Information about Options relays

• Information about Analog inputs (only visible when option is activated)

1

Cabinet in work mode. See

§5.3 Starting up the cabinet

on page 19.

• Push button (Menu).

• Push button (B).

Cabinet in work mode - Safe Monday 11:06:33

MENU

Socket=Off

A => Hour counter information B => Status cabinet C => Settings

A

B

C

Esc

2

Status Display:

Status display shows

Information status cabinet

A = Enter

=>

<=

Esc

3

Status Information :

Example with colours)

Airflow 0.36 < < 0.54

• Push button .

Cabinet: Work mode Airflow 0.36 < < 0.54

=>

<=

Esc

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Status information cabinet shows (see example).

• Middle numbers are the actual air speeds (yellow);

• Left and right numbers are the set up alarm borders

(red).

4

Information fan shows

• Push button

(=>).

The seven-digit number in the upper right corner is only meant for service aims.

• Push button

(Esc) for starting menu.

Information fan setting (0-1000) 1110011 Off: 0 Power save: 350

W

ork mode: 520 Actual: 537

=>

<=

Esc

Information about the installed options

(The display only shows when the options are installed)

1

Cabinet in work mode. See

§5.3 Starting up the cabinet

on page 19.

• Push button (Menu).

• Push button (B).

Cabinet in work mode - Safe Monday 11:06:33

MENU

Socket=Off

A => Hour counter information B => Status cabinet C => Settings

A

B

C

Esc

2

Information about the installed options is given (example):

• Push button

(=>).

Information status cabinet

A = Enter

=>

<=

Esc

Installed Options 1 Socket present, UV inst. 1 flowsens

=>

<=

Option

Esc

From here there are 3 possibilities (examples):

- 3a. Screen I

- 3b. Screen II

- 3c. Screen III

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3a

Options Screen I Starting up from Step 2

Installed options display shows.

• Push button

(Option).

For explanation codes see

Appendix VIII: Information

installed

options

on page 52

.

• Push 2x button

(Esc) for starting menu.

Installed Options 1 Socket present, UV inst. 1 flowsens

=>

<=

Option

Esc

Option Exhaust fan Relays #C2

Esc

3b

Options Screen II Starting up from Step 2

Installed options display shows.

• Push button (=>).

• For explanation codes see

Appendix VIII: Information

installed options on page 52.

• Push button

(Esc) for starting menu.

Installed Options 1 Socket present, UV inst. 1 flowsens

=>

<=

Option

Esc

Installed Options Relays #A1 Relays #B1

=>

<=

Esc

3c

Options Screen III (Display only appears when analogue options are installed) Starting up from Step 2

• Push 2x button

(=>).

For explanation codes see

Appendix VIII: Information

installed options on page 58.

•

Push button (Esc) for starting menu.

Analog inputs AD1 5.0 C AD2 1.0 µM A = Enter

=>

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5.12 Settings

In settings more details are given about:

• Preparations for disinfection

• Activating the user code

• Factory adjustments

• Testing of alarms

• Change the user code

• Change language

Disinfection (Not applicable for this type of cabinet)

1

Cabinet in work mode. See

§5.3 Starting up the cabinet

on page 19.

• Switch off the cabinet with button .

• Push button (Menu).

• Push button

(C).

• Push button

.

Cabinet in work mode - Safe Monday 11:06:33

MENU

Socket=Off

A => Hour counter information B => Status cabinet C => Settings

A

B

C

Esc

2

• Push button (Esc) to leave the disinfection.

Preparations for disinfection

0000 (Enter code)

A = Enter

=>

+

-

Esc

Activating the user code

See

Appendix IX: User code on page 61

.

Factory adjustments

1

Cabinet in work mode. See

§5.3 Starting up the cabinet

on page 19.

Cabinet in work mode - Safe Monday 11:06:33

MENU

Socket=Off

2

Factory adjustments:

• Push button

(Menu).

• Push button

(C).

• Push 2x button (=>).

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Factory adjustment display shows. Factory settings can be changed here (authorized personnel only). See service manual for more information. (Version: X.X =version of Display board, I/0: VX.XX= version of IO board, OPT: VX.X = version option board)

• Push button

.

• Enter the code for "Factory adjustment" (authorized personnel only).

• Push button

.

• Push button (Esc) for starting menu.

Factory adjustment 0000 (Enter code)

>>

+

-

Esc

Factory adjustments Version: X.X xxxxxx IO: VX.XX OPT: VX.X A = Enter

>>

+

-

Esc

Testing of alarms

For service purposes only! More information given in Appendix VI: Alarm-test procedure

on page 55.

1

Cabinet in work mode. See

§5.3 Starting up the cabinet

on page 19.

Cabinet in work mode - Safe Monday 11:06:33

MENU

Socket=Off

2

Testing of alarms display shows:

• Push button and (C).

• Push 3x button .

• Push button .

• Enter service code.

Testing of alarms 0000 (Enter code) A = Enter

>>

+

-

Esc

3

For service purposes only!

The various values of the fan and velocities are shown on the display. In case of interference, inform you service organization.

Change the user code

See

Appendix IX: User code on page 61.

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Change language

To change the language, switch off the cabinet and switch off all functions. Then the language can be changed and confirmed. As confirmation the 3 LED’s (right) light up for 1 second and 2 short beeps will sound. The cabinet will be switched on automatically.

1

Cabinet in work mode. See

§5.3 Starting up the cabinet

on page 19.

Cabinet in work mode - Safe Monday 11:06:33

MENU

Socket=Off

2

Change the language

• Push button (Menu).

• Push button (C).

• Push 5x button (=>).

• Push button .

Conditions: The fan has to be switched off (push

) and

sockets and FL-light must be switched off.

• Push button

(Change) to change the language.

• Push button

.

Taal Language Sprache Engels English Englisch

A = Enter

Change

Esc

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6 Alarms

Figure 5 Operating panel

When there is an alarm situation the alarm indicator flashes red

and there is an acoustic

signal. The safe working conditions are no longer granted.

Push button for giving an acknowledgement that the user has seen the alarm. The acoustic signal will mute, the alarm indicator will (always) keep on burning. Before acknowledging the alarm, the user code must be entered (only when the user code is activated). An acknowledged alarm (with button A) shall be repeated every 7 minutes, as long as the alarm situation continues. The buzzer has a SPL, sound pressure level, of at least 10 dB (A more than the sound pressure of the working cabinet. See

Appendix X: Required specifications

on page

63.

GENERAL DANGER

Make sure that there are no alarm situations during the use of the cabinet. Never work with a cabinet with activated alarm signals.

The different types of alarm signals will be discussed in the following chapter.

6.1 Flow alarms

If one of the following alarms occurs and no apparent cause can be found, the service department has to be contacted. They will ask for the status of the cabinet, which helps to find possible causes (see

§5.11 Information status cabinet on page 32

).

Flow too low

Airflow too low

Figure 6

Product protecting crossflow is too low.

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Product protection becomes less, there is a chance that aerosols from the outside go into the working area.

Flow too high

Airflow too high

Figure 7

Product protecting crossflow is too high. Product protection stays intact.

6.2 Other alarms

Other alarms are:

Fan failure

Figure 8

Most likely the fuse is broken. Replace it with a new one. If the alarm is still there, contact your service organization. To reset this alarm you must disconnect the power plug from the main voltage.

Communication error

Figure 9

Contact your service organization.

Overview possible alarms

No alarm Flow too low Flow too high

Product protection: Yes No Yes

Table 1: Alarm situations in work position

Procedure in case of alarms

In case the alarm is still present:

Stop working, and push

button

or the standard operation procedure has to be followed.

The cabinet goes into the saving position.

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Read the alarms from the

display. Contact your service organization.

Working with the cabinet is not possible anymore.

Cabinet in work mode -Not Safe Monday 11:06:33

MENU

Socket=Off

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7 Cleaning

Only the responsible safety officer (safety officer or the responsible examiner) can decide if this procedure is valid or not. Additional standard operation procedures can be necessary.

7.1 Cleaning the installation

The installation has to be cleaned regularly. Preferably, each time after the installation has been used. Diluted disinfectants may be used. In most cases, hot water with a cleaning agent will be sufficient. Chlorine containing cleaning agent is not recommended, because even small concentrations chlorine may result in an oxidizing effect on the material of the installation. It is important to clean the worktop (see

§ 4.3 on page 13)

regularly. A 1% solution of Natriumdodecylsulfat * (SDS-solution CAS-no. 151-21-3) in demineralised water could be applied for cleaning. Remove the waste and place it in an appropriate container.

*) Literature:

See Mallinckrodt J.T. Baker data sheet: SDS is MSDS number No S3670 Mallinckrodt Baker Inc. 222 Red School Lane Phillipsburg, NJ 08865

Procedure for cleaning the installation

Never clean a used installation without precaution (for instance disinfection)

 Switch the installation in the working mode (see

§5.3 Starting up the cabinet on page 19)

;

 Put on gloves;  Clean the surface with the cleaning-solution on a tissue ;  Repeat this action with a new tissue;  Clean the surface with a moist cloth;  Repeat this action;  Dry the surface with a paper tissue.

7.2 Cleaning the UV-light (optional)

Never clean a used installation without precaution (for instance

disinfection)

DANGER FOR ELECTROCUTION

The UV-light must be cleaned regularly with alcohol (70%). Put on gloves and switch of the cabinet and let the UV-light cool down before cleaning. After cleaning the UV-light tube must be dried before using it.

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8 Small maintenance and testing

BE CAREFUL!!

Before starting service with the cabinet a written declaration “that the cabinet is decontaminated”

must be present. The responsible person (laboratory supervisor) will decide if the cabinet has to

be decontaminated so that when servicing the installation and the HEPA-filters there is no danger

for the service engineer, labour personnel, the laboratory and the surroundings of the cabinet.

8.1 Periodic maintenance

A periodic maintenance has to take place regularly. To a certain extent, this depends on the frequency of use of the cabinet. Contact your service organization for advice. Guideline for testing and maintenance given Clean Air Techniek B.V. is every 12 months at least.

 Validate the system on safety;  Check for correct functioning of the electrical system;  Check the HEPA filter for efficiency and leakage;  Verification/calibration of the assembled air speed sensor(s);  Check and adjust the alarm system.

8.2 Replacement of the pre-filter

(See 4.6 Pre-filter

on page

13)

Supplies needed:

 Plastic bag (minimum measurement 75x50 [cm] with closure);  Two pair of gloves;  Tape.

Procedure:

 Switch off the installation;  Put on the gloves;  Fold the edge of the plastic bag ±10 cm;



Figure 10 Folding the edge of the bag ±10 cm

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Figure 11 Positioning the left hand in the plastic bag

 Pull the pre-filter towel with your right hand;  Put the filter into the plastic bag;  Fold back the edge of the plastic bag, not touching the inner side of the plastic bag;  Press the air out of the bag;  Seal the plastic bag airtight;  Remove the plastic bag and place it in an appropriate container;  Put on new gloves;  Place a new pre-filter towel;  Remove the gloves and put them in the appropriate container.

8.3 Replacing the fluorescent-light (FL light)

When an FL light needs to be changed, switch off the power of the installation. The upper front panel needs to be opened. Unscrew the nuts of the coverplate.The transparent light plate needs to be removed in to the workarea. Replace the FL tube for a new one (see

Figure 12)

. Reposition all

parts on the installation.

DANGER FOR ELECTROCUTION

Figure 12 Position of the FL-tube

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8.4 Service contact

For advice or any technical questions please contact your service organisation. Please refer to the following items:

• Type, Class, Project number and Serial number mentioned on the type plate

(for the position of the type plate see

page 12

and

page 57

);

• Version number of the software used in the cabinet.

Software Version

1

Cabinet in work mode. See

§5.3 Starting up the cabinet

on page 19.

Cabinet in work mode - Safe Monday 11:06:33

MENU

Socket=Off

2

Software version:

• Push button (Menu).

• Push button (C).

• Push 2x button (=>).

Factory Adjustments

Version: X.X xxxxx I/O: VXXXX OPT: VX.X

>>

+

-

Esc

8.5 Service contract

For information and orders concerning service or service contracts please contact Clean Air Techniek B.V.

8.6 Testing

Recommended tests for first installation or after changing the HEPA filters are:

- Velocity tests (see

Appendix IV Measuring method air velocities

on page 53);

- Filter Integrity tests (see Appendix III: Efficiency test of the HEPA-filters

on page 52);

- Alarm tests (see Appendix VI: Alarm-test procedure

on page 55).

Recommended tests after installing with a regular interval are:

- Velocity tests (see Appendix IV Measuring method air velocities

on page 53);

- Filter Integrity tests (see Appendix III: Efficiency test of the HEPA-filters

on page 52);

- Alarm tests (see Appendix VI: Alarm-test procedure

on page 55).

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9 Technical specifications

9.1 Physical surrounding

Transport physics

CLF 475 CLF 575 CLF 675

Surrounding temperature

[°C]

-25 tot 55 -25 tot 55 -25 tot 55

Surrounding temperature (max 24 [h])

[°C]

-25 tot 75 -25 tot 75 -25 tot 75

Humidity

[%]

20 tot 90 20 tot 90 20 tot 90

In use physics

CLF 475 CLF 575 CLF 675

Surrounding temperature

[°C]

15 tot 30 15 tot 30 15 tot 30

Humidity (not condensed)

[%]

30 tot 80 30 tot 80 30 tot 80

9.2 General specifications

Dimensions

CLF 475 CLF 575 CLF 675

Front aperture (lxh)

[mm]

1190 x 730 1495 x 730 1800 x 730

Outer meas. (without support frame (lxhxd)

[mm]

1290 x 1350 x

890

1595 x 1350 x

890

1900 x 1350 x

890

Height including. Support frame 810 [mm]

[mm]

2082 2082 2082

Interior dimensions (lxhxd)

[mm] 1190 x 730 x

580

1495 x 730 x

580

1805 x 730 x

580

Working area (lxd)

[mm]

1190 x 540 1495 x 540 1800 x 540

Mass

[kg]

225 270 325

Filter

CLF 475 CLF 575 CLF 675

Pre-filter

(EN 779)

[mm]

G3 G3 G3

Crossflow filter

[mm]

HEPA 12P7 HEPA 15P7 HEPA 18P7

Performance

CLF 475 CLF 575 CLF 675

Sound level (according to ISO 11201)

[dB A]

<58 <58 <54

Average crossflow speed (in work mode)

[m/s]

0,45 ±0,05 *

1

0,45 ±0,05 *1 0,45 ±0,05 *

1

Average crossflow speed (in standby mode)

[m/s]

0,20 ± 0,05 0,20 ± 0,05 0,20 ± 0,05

Airflow (work mode) +/-10%

[m3/h] 1400 1800 2150

*1

As where no individual measurement should differ more than 20% from the mean. All measurements must in between 0,36 m/s

and 0,54 m/s.

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Electrics

CLF 475 CLF 575 CLF 675

Power connection

[V] [Hz]

230 +/- 5%

50

230 +/- 5%

50

230 +/- 5%

50

Needed main fuse box security

[A]

16 16 16

[V] Max. 48 Max. 48 Max. 48

J6: Alarm, potential free contact

[A] Max. 1 Max. 1 Max. 1

Electrical insulation

Class 1 Class 1 Class 1

Electrical safety IEC 61000-4-11 Installation cat.

Class A

II

Class A

II

Class A

II

U

max.

[V]

I

max

[A]

230

3,15

230

3,15

230

3,15

Power sockets

P

max.

[W]

725 725 725

Power consumption in standby mode (with light switched off) excl. maximum power socket

P [J/s,W]

I [A]

373

1,62

460

2,0

465

2,02

Power consumption in work mode (with light switched on) excl. maximum power socket

P

nom

[J/s,W] I

nom.

[A]

708

3,08

805

3,5

1000

4,35

Power consumption in work mode (with light switched on) incl. maximum power socket

P

nom

[J/s,W] I

nom.

[A]

1433

6,23

1530

6,6

1725

7,5

Power consumption in max mode fan (with light switched on) excl. maximum power socket

P

max

[J/s,W]

I

max.

[A]

980

4,26

1383

6,0

1427

6,2

Power consumption in max mode fan (with light switched on) incl. maximum power socket

P

max

[J/s,W]

I

max.

[A]

1705

7,41

2108

9,16

2152

9,35

Lighting

CLF 475 CLF 575 CLF 675

TL-High output

2x 2x 2x

Color

white white

white

Diameter

[mm] Ø26 Ø26 Ø26

Length

[mm]

892 1198

1500

Power

[W]

30 36 58

Intensity (mean)

[Lux]

> 900 > 900 > 900

Fuses I/O board

CLF 475 CLF 575 CLF 675

F1: PCB; 24 [V]

[A] T

0,5 0,5 0,5

F2: Option

[A] T

3,15 3,15 3,15

F3: Lighting

[A] T

1,6 1,6 1,6

F4: UV

[A] T

0,5 0,5 0,5

F6: Socket 1

[A] T

3,15 3,15 3,15

F7: Fan

[A] T

8 8 8

F8: PCB

[A] T

1,6 1,6 1,6

F9: PCB

[A] T

1,6 1,6 1,6

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Options:

UV

CLF 475 CLF 575 CLF 675

Type

UV-C

Power

[W]

30 30 30

Length UV-wave

[nm]

253 253 253

Diameter

[mm]

Ø 28 Ø 28 Ø 28

Length

[mm]

892 892 892

Bunsen burner

CLF 475 CLF 575 CLF 675

Voltage

[V] DC

9 9 9

Power

[W]

2 2 2

See also Appendix X: Required specifications

on page

63 and Appendix XI: Recommended spare

parts list

on page

64.

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10 Trouble shooting

Fault Cause Remedy

Socket is not activated

Activate socket on display push on

No power on socket of the cabinet

Fuse is broken Replace the fuse

UV equipment is not installed x UV button is not visible on display

Option UV is not programmed UV option has to be programmed please

contact your service organization Contacts of the FL are not locking in the power connections

Turn the FL-light slightly FL-light is not working

UV light is on Switch of the UV light

Cabinet is locked User code must be entered Enter the user code (or de-activate the user

code see § 5.12 Change the user code on

page 36)

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Appendix I: Support frame CLF

For every type of cabinet from CLF-series a specific support frame is available.

Figure 13 Example of a support frame

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Appendix II: Replacement of the HEPA-filters

BE CAREFUL!!

Before starting service with the cabinet a written declaration “that the cabinet is decontaminated” must be present. The responsible person (laboratory supervisor) will decide if the cabinet has to be decontaminated so that when servicing the installation and the HEPAfilters there is no danger for the service engineer, labour personnel, the laboratory and the surroundings of the cabinet.

Clean Air Techniek B.V. strongly recommends special trained technicians to carry out filter exchange. Certified service organizations are recommended. At all times keep to the written procedures in this manual!

1. When does a HEPA filter need to be replaced?

Under normal circumstances the serviceable life time of a HEPA filter is several years (mostly between 5 and 10 years). The filter should be replaced whenever the air velocity and/or the filter Integrity are no longer in compliance with the required specifications. The cabinet has a microprocessor that is automatically regulating the fan speed to compensate for main power fluctuations and filter pollution.

2. replacing the HEPA-filter

Make sure that the cabinet has been properly decontaminated so as to ensure that no danger exists for the service engineer, the laboratory personnel and the environment. If the customer has a special procedure for the disposal of contaminated material, then this should be followed. In case the service engineer does not think that this is sufficient, then proper precautions should be made in consultation with the person responsible for the cabinet. If there is no special procedure it is best to wear at least gloves and the protective clothing normally worn during work with the cabinet. It is also advised to have a breathe protection e.g. with a semi-facial mask with HEPA filters.

Supplies needed:

• Plastic bag with closure (minimum measurement depends on the volume of the HEPA filter);

• Two pair of gloves;

• Semi-facial mask with HEPA filters;

• Tools (knife, spanner or socket wrench, Alien key);

• Tape;

• Chemical disposal container or chemical disposal procedure.

Removing the old HEPA filter

• Switch off the cabinet and pull out the power plug;

• Put on the gloves and keep an extra pair ready for use;

• Put on your breathe protection e.g. with a semi-facial mask with HEPA filters;

• Remove the lower back panel;

• Loosen the bolts of the pressure construction;

• Take HEPA-filter out of the cabinet into a plastic back;

• Remove the HEPA-filter conform the regulations;

• Loosen the bolts of the pressure construction;

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• Take the HEPA filter out of the cabinet and put it into an appropriate plastic bag;

• Seal the plastic bag airtight;

• Remove the gloves and put them in the appropriate container.

Position the new HEPA filter

• Unpack the new filter, check specifications and register the serial number and specifications;

• Filter certificate has to be stored on a safe place;

• Put Vaseline on the seal of the HEPA filter (both sides);

• Position the HEPA filter (take care for possible damage of the sealings!);

• Place the new HEPA-filter;

• Put the cabinet together in the reverse way as described above;

• Put of your gloves and put these in an appropriate bag;

• Do an efficiency test according to the procedure described in Appendix III.

The valid procedures for the disposal of possible contaminated material must always be followed. When the service engineer thinks this is not enough this will be discussed with the responsible person so that enough precautions can be made.

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Appendix III: Efficiency test of the HEPA-filters

ATTENTION!

Before starting service with the cabinet always ask the responsible person if there is no danger for the service engineer, labor personnel, the laboratory and the surrounding of the cabinet.

Clean Air Techniek B.V. strongly recommends special trained technicians to carry out filter tests. Certified service organizations are recommended. At all times keep to the written procedures in this manual!

Requirements

Efficiency test by means of a particle counter

The HEPA-filter must have an efficiency of 99,995% MPPS*. A local measured value can be a factor 10 higher, ≤ 0,05%.

*) Most Penetrating Particle Size

Efficiency test with a photometer

The HEPA-filter must have an efficiency of 99,99%. A local measured value must be ≤ 0,01%. When a HEPA-filter does not meet the EN1822, it is allowed to repair it. The surface of the reparation must not be more that 5% of the total surface of the HEPA-filter. When this does not have sufficient effect the HEPA-filter must be replaced as described in Appendix II: Replacement of the HEPA-filters on page 50.

Test aerosol

In a CLF cabinet, test aerosol can be added on the fan suction side after removing the pre-filter on top of the cabinet (do not remove the metal grid under prefilter to prevent contact with the rotating fan and electronic components). Switch on the installation.

GENERAL DANGER

You can harm yourself and others seriously if you do not follow the procedures carefully

HIGH VOLTAGE

The 100% measure point (upstream concentration) of the crossflow HEPA-filter is positioned on the top of the crossflow plenum. The HEPA filter can be scanned on the downstream side (in the workarea).

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Appendix IV Measuring method air velocities

Requirements

The measurement of air velocities in the cabinet is performed according to manufacturer specifications as described in chapter 9 on page 45.

Air velocities crossflow

• Switch on the cabinet;

• Measure the airspeeds in a rectangular grid with a distance between each measurement point

of no greater than 300 x 300 mm. The rectangular grid must be 150 mm away from each side that encloses the filter.

• Measure with an anemometer in a verticall plane at 150 mm from the HEPA filter

• This measurement must be done for at least one minute on each position.

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Appendix V: Lay-out boards

Interface board

Figure 14 Interface board

Control board

Figure 15 Control board E010001 rev F

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Appendix VI: Alarm-test procedure

(Authorized personnel only) To test the alarm limits, the automatic fan control must be overruled, so the fan power can be set by hand. The entire state of the cabinet will stay unchanged, except for the fan-power. The required test-code is 7733. In this state, each 30 second, two short audible signals will be heard, to be remembered at the initial unsafe mode. After 30 minutes after the last button is touched, the fan returns to its work mode.

Alarm-test procedure

1

Cabinet in work mode. See

§ 5.3 Starting up the cabinet

on page

19.

• Push button (Menu).

• Push button (C) .

Cabinet in work mode – Safe

Monday 11:06:33

MENU

Socket=Off

A => Hour counter information B => Status cabinet C => Settings

A

B

C

Esc

2

Alarm test

• Push 3x button (>>).

• Push button

.

• Enter the test code: 7733.

• Push button

.

Testing of alarms

A = Enter

>>

<<

Esc

Testing Alarms

0000 (Enter code) A = Enter

>>

+

-

Esc

3

Alarm test settings (NM = Normal mode, PS = Power save mode, DF = Data of cross Flow, IF = Inflow, (not applicable) CV = Current value)

• Push button

(+) or (-) in order to adjust the

fan speed. Value CV will change.

NM 500 Off 0 PS 300 CV 490 DF Off 0.00 PS 0.19 0.36 < 0.45 < 0.54 IF Off 0.00 PS 0.00 0.00 < 0.00 < 0.00

+

-

Esc

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Middle numbers are the actual values from the airspeed indicators, which are changeable with the

use of the buttons

(+) and (-). First and last values are the set up alarm borders (for example: Data of Crossflow DF: lowest level is 0.36 m/s, highest level is 0.54 m/s and the actual value for crossflow velocity is 0.45 m/s). The fan speed is shown in tenths of percents (0 = min. and 1000 = max.).

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Appendix VII: Stickers

1) Sticker cabinet type. This sticker can be found on the outside on top of the cabinet. For an

example of the sticker, see the picture underneath.

2) Sticker I/O board.

3) Electro

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Appendix VIII: Information installed options

Installed options microprocessor

This chapter describes the codes from § 5.11 Information about the installed options on page 33. Menu B from the microprocessor.

• Start up in “Menu-Display”,

• Push button

(Menu),

• Push button

(B),

• Push button

(=>) for screen I,

• Push button (=>) for screen II,

• Push button

(=>) for screen III.

Screen I Installed options – Option

Options No Electrical window: E#0

Esc

Figure 16 Example of screen I

Explanation of the codes from the menu:

• #E0: no electrical window;

• #E1: electrical window; no functionality for fan; (only available for EF/S series)

• #E2: work mode, if cabinet is switched on;

• #C3 = relay K2 on option print;

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Screen II Installed options – relays

Installed Options Relais #A1 Relais #B1

=>

<=

Esc

Figure 17 Example of screen II

Overview functions of relay K8, #A1-A12

Alarm #A1 - #A12 relay switching K8, on output J5 at the IO print: Set up from #A1 until #A12: A1 Relay ON = A & ( HD * LD * HI * LI ) DEFAULT A2 Relay ON = A & ( HD * LD * HI * LI * R ) A3 Relay ON = W & ( HD * LD * HI * LI ) A4 Relay ON = W & ( HD * LD * HI * LI * R ) A5 Relay ON = W & ( HD * LD ) A6 Relay ON = A & ( HD * LD ) A7 Relay OFF = A & ( HD * LD * HI * LI ) A8 Relay OFF = A & ( HD * LD * HI * LI * R ) A9 Relay OFF = W & ( HD * LD * HI * LI ) A10 Relay OFF = W & ( HD * LD * HI * LI * R ) A11 Relay OFF = W & ( HD * LD ) A12 Relay OFF = A & ( HD * LD )

Explanation codes used above: W = Working mode, S = Save mode, A = Cabinet on and spare mode, HD = High down/crossflow alarm, LD = Low down/crossflow alarm, HI = High inflow alarm, LI = Low inflow alarm, R = Window alarm, & = AND function, = OR function.

Functions are factory adjustments and cannot be changed by the user.

Overview functions of relay K3, #B1-B5

Alarm #B1 - #B5 relay switching K3, on output J22 at the IO print:

• #B1: the K3 relay is activated if the main fan is switched on (working mode / saving mode);

• #B2: the K3 relay is activated if the main fan is on half speed mode (saving mode);

• #B3: the K3 relay is activated if the main fan is in the working mode;

• #B4: the K3 relay is activated if the option Disinfection in the menu is chosen;

• #B5: the K3 relay is activated if there is an alarm from the analogue inputs.

Overview functions of relay K2, #C1-C5

Alarm #C1 - #C5 relay switching K2, on output J14 at the Option print:

• #C1: the K2 relay is activated if the main fan is switched on (working mode/ saving mode);

• #C2: the K2 relay is activated if the main fan is on half speed mode (saving mode);

• #C3: the K2 relay is activated if the main fan is in the working mode;

• #C4: the K2 relay is activated if in the menu is chosen for the option Disinfection;

• #C5: the K2 relay is activated if there is an alarm from the analogue inputs.

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Screen III Analogue inputs (only if installed)

Analog inputs AD1 5.0 C AD2 1.0 µM A = Enter

=>

<=

Esc

Figure 18 Example of screen III

Analogue inputs can be used to program alarm settings for e.g.:

- temperature (°C) of working surface;

- temperature (°C) of work area;

- particle counters (ppm);

- relative humidity (%);

- pressure (Pa) in plenum.

If alarm limits are exceeded, an alarm will sound as short beeps with intervals.

To install alarm limits, start from the menu as described in § 5.11 Information status cabinet on page 32. (The display only shows when the options are installed):

1

Starting from screen III

• Push button

.

Analog inputs AD1 5.0 C AD2 1.0 µM A = Enter

=>

<=

Esc

2 Settings for High and Low Alarm

• Push button (=>).

• Choose the required limits (L=Low, H=High) for AD1

and AD2 using button (+) and (–).

• Push button (Esc) to confirm the settings and to go back to the starting menu.

Analog inputs Change AD1 L AD1 5.0 C L= 0.0 H= 0.0 AD2 1.0 µM L= 0.0 H= 0.0

=>

+

-

Esc

An alarm can be transferred, depending on the code:

- #B5, through relay K3;

- #C5, through relay K2 (option print).

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Appendix IX: User code

Activating the user code

The function “User code Active/not active” makes it possible to lock the control of the installation. To change this state the valid user code has to be entered. The new state (active or not active) is valid after a period of 5 minutes (after touching the last button). The pre installed valid user code is 0001. In case of emergency there is a special code to break the unknown or forgotten user code. In that case enter code 2882 and the original pre installed code, 0001, is valid again.

1

Cabinet in work mode. See

§ 5.3 Starting up the cabinet

on page

19.

• Push button (Menu).

• Push button (C).

• Push button

(=>).

User code mode appears.

• Push button .

The information for the user code shows. The user code can be activated or deactivated.

• Enter the user code using button (>>), (+)

and (-).

• Push button .

• Push button (Esc) for starting menu.

Cabinet in work mode – Safe

Monday 11:06:33

MENU

Socket=Off

User code: not active

A = Enter

=>

<=

Esc

Function locked after 5 minutes 0000 (Enter code)

U

ser code: Not active A = Enter

>>

+

-

Esc

User code: Active

A = Enter

=>

<=

Esc

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Changing the user code

1

Cabinet in work mode. See

§ 5.3 Starting up the cabinet

on page

19.

Cabinet in work mode – Safe

Monday 11:06:33

MENU

Socket=Off

2

Change the user code

• Push button (Menu) and (C).

• Push 4x button (=>).

• Push button

.

• Enter actual user code.

• Push button .

• Enter the new valid user code.

• Push button .

User code: 0000 (Enter code) A = Enter

>>

+

-

Esc

Input user code:

N

ew code: 0000

Old code: 0001 A = Enter

>>

+

-

Esc

The pre installed valid user code is 0001. In case of emergency there is a special code to break the unknown or forgotten user code. In that case enter code 2882 and the original pre installed code, 0001, is valid again.

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Appendix X: Required specifications

Overview of the required specifications

Specifications

Requirement (shortened) According to:

Lighting Average value at least 540 lux at locations on side to side center line of work

surface

IEST-RP-CC-002.3:2009

Sound level <65 [dB(A)] when background level is <55 [dB(A)] according to ISO11201. ISO 11201 Sound level Buzzer Exceed 10 [dB(A)] more than installation sound pressure Manufacturer

specifications

Stability Conform to EN 61010-1:2002-08 and EN 12100-1:2003 and 12100-2:2003 EN 61010, EN 12100-

1:2003 and 12100-2:2003

Materials, general The material likely to be in contact with micro organisms should be uniformly

corrosion resistant, non-flammable and non-absorbing

Manufacturer specifications

Materials, general Materials and sealants for joints should be durable and resistant to cleaning

and disinfection agents and resistant to general use of cabinet.

Manufacturer specifications

Side walls Safety glass or UV-resistant safety plastics Manufacturer

specifications

Side walls Conform to EN 12100-1:2003 and 12100-2:2003 EN 12100-1:2003 and

12100-2:2003 Electrical safety Conform to EN 61010 EN 61010 Gas supply (optional) safety

Conform to EN 12100-1:2003 and 12100-2:2003 EN 12100-1:2003 and

12100-2:2003 Ergonomics Maintenance can be carried out safely on the cabinet after installation Manufacturer

specifications Ergonomics Considered according to prEN ISO 14738:1997 to prEN ISO 14738:1997 Filter efficiency test / Aerosol challenge method

Particle counter: <0,05% Aerosol photometer: <0,01%

IEST-RP-CC-002.3:2009

ISO 14644-3:2005 Workspace classifcation Maximum permitted number of particles / m3 at rest :

0,5 µm = 3520, 5,0 µm =20

ISO 14644-1:1999 / GMP

Annex 1, March 2009 Design and airflow velocities

V

avg

0,45 +/- 0,05 m/s in work mode as where no individual measurement should differ more than 20% from the mean. All measurements must in between 0,36 m/s and 0,54 m/s.

Manufacturer specifications GMP Annex 1, March 2009

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Appendix XI: Recommended spare parts list

Component Type specific Art. no.

Crossflow HEPA filter CLF 475 1001207

Pre-filter CLF 475

Fan CLF 475

3000002

FL-lighting CLF 475

1440003

FL-Holder CLF 475

1460003

Crossflow HEPA filter CLF 575

1001507

Pre-filter CLF 575

Fan CLF 575

3000033

FL-lighting CLF 575

1440003

FL-Holder CLF 575

1460002

Crossflow HEPA filter CLF 675 1001807

Pre-filter CLF 675

Fan CLF 675

3000033

FL-lighting CLF 675

1440001

FL-Holder CLF 675

1460001

Component Type specific Art. no.

Air velocity-sensor crossflow

All

1330023

Starter FL

All

2040001

Mains filter

All

6400010

Optional:

All

Gas-/vacuum tap

All

2800002/2800004

Bunsenburner

All

Misc.

UV-tube

All

1440008

UV holder

All

2030003

UV starter

All

2040001

Ballast UV

All

1240003

Nightdoor (for UV protection) CLF 475 S402001

Nightdoor (for UV protection) CLF 575 S404001

Nightdoor (for UV protection) CLF 675 S403001

Articles mentioned above can be ordered at the service organization Particle Measurement & Validation b.v. Particle Measurement & Validation b.v. Phone: +31 (0) 348 423661 Kuipersweg 37 Fax: +31 (0) 348 422684 3449 JA Woerden E-mail: info@pmvbv.nl The Netherlands Internet:

www.pmvbv.nl

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Appendix XII: TUV Low Pressure Mercury Lamps (Optional)

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Appendix XIII: Statement of the agreement for machines

Manufacturer: Clean Air Techniek B.V.

Address: Kuipersweg 37

3449 JA Woerden The Netherlands Phone: +31 (0) 348 411114 Fax: +31 (0) 348 422684 E-mail:

info@cleanair.eu

Internet: www.cleanair.eu

Hereby declares that:

Type: _______________________ Project number: _______________________ Serial number: _______________________

is in compliance with the following directives:

• Machine Directive (2006/42/EC);

• Low Voltage Directive (2006/95/EC);

• Electromagnetic Compatibility Directive (2004/108/EC).

And declares furthermore that the following national technical standards and specifications are used:

• NEN-EN 1822 High efficiency particulate air filters;

• ISO 14644;

• GMP Annex 1.

Signature:

………………………………………………

Name: ………………………………………………

Quality controller By order of the production controller

Woerden, date ………………………………………………

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Appendix XIV: Memo

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Index

Alarm situations in work position ...............39

Assembly-instruction.................................10

Bunsen burner lead-through set ................16

Change language .....................................37

Change the user code ...............................62

Cleaning the installation............................ 41

Clock 7 days............................................. 25

Code alarmtest......................................... 55

Control board ........................................... 54

Control sockets......................................... 22

Control UV

...............................................22

Default code ............................................19

Dismantling and disposal ..........................11

Display ....................................................18

Efficiency test with a photometer .............. 52

Emergency code....................................... 61

EN 12100-1&2..........................................63

EN 61010................................................. 63

Factory adjustments .................................35

Fixed keys................................................18

FL light ....................................................43

Function keys ...........................................19

Gas connection.........................................15

GMP Annex 1 ...........................................63

Hour counter info and reset ................ 23, 26

IEST-RP-CC-002.3 .................................... 63

Information status cabinet ........................ 32

Installed options........................... 33, 58, 60

Interface board ........................................ 54

ISO 11201 ...............................................63

ISO 14644-1 ............................................63

ISO 14644-3 ............................................63

ISO 14738 ...............................................63

Lay-out boards ......................................... 54

Menu functions......................................... 23

Night mode .............................................. 21

Part list critical components ...................... 64

Periodic maintenance ............................... 42

Placing the cabinet ................................... 11

Power save mode..................................... 21

Procedure in case of alarms ...................... 39

Replacement of the pre-filter .................... 42

Replacing the Fluorescent-light ................. 43

Replacing the HEPA-filter .......................... 50

Screen I .............................................34, 58

Screen II ............................................34, 59

Screen III ...........................................34, 60

Service contact ........................................ 44

Service Contract....................................... 44

Set up 7 days clock UV ............................. 24

Set up actual time .................................... 31

Set up cabinet 7 days clock....................... 30

Set up socket 7 days clock ........................ 29

Settings................................................... 35

Signals .................................................... 19

Socket off ................................................ 23

Socket on ................................................ 22

Software Version...................................... 44

Standby mode ......................................... 21

Starting up the cabinet ............................. 19

Statement of the agreement for machines . 66

Stickers ................................................... 57

Technical specifications ............................ 48

Test aerosol............................................. 52

Testing of alarms ..................................... 36

Timer ...................................................... 25

Turn off................................................... 21

Using the cabinet ..................................... 18

UV off...................................................... 22

UV on...................................................... 22

Vacuum connection .................................. 16

Clean Air CLF 475, CLF 675, CLF 575 User Manual

Specifications and Main Features

Frequently Asked Questions

User Manual