Metrohm tiamo 1.3 User Manual

CH-9101 Herisau/Switzerland
E-Mail [e-mail]
Internet www.metrohm.com

tiamo User Manual

Program version 1.3

8.101.0033 06.2008/dö/pkl

Teachware
Metrohm AG
Oberdorfstrasse 68
CH-9101 Herisau

[e-mail]

This User Manuel is protected by copyright. All rights reserved.

Although this User Manuel has been prepared with the greatest care, errors cannot be completely ex­cluded. Should you notice any please contact the above address.

Table of contents

Chapter 1 Introduction .................................. 1

1.1 Welcome to tiamo ................................................................1

1.2 User interface ......................................................................2

1.3 Integration of devices..........................................................3

1.4 Method editor .......................................................................4

1.5 Database ..............................................................................5

1.6 Communication ....................................................................6

1.7 Compliance ..........................................................................6

1.8 Versions................................................................................7

1.9 Online Help...........................................................................8

1.10 What's new in tiamo 1.3?.....................................................8

Chapter 2 General program functions .......... 9

2.1 Program parts ......................................................................9

2.2 Login/Password protection................................................10

2.2.1 General .....................................................................................10

2.2.2 Login .........................................................................................11

2.2.3 Manual logout........................................................................... 11

2.2.4 Automatic logout......................................................................11

2.2.5 Change password.....................................................................12

2.3 Electronic signatures.........................................................13

2.3.1 Rules .........................................................................................13

2.3.2 Procedure ................................................................................. 13

2.3.3 Signature Level 1 .....................................................................14

2.3.4 Signature Level 2 .....................................................................15

2.3.5 Delete Level 2 signatures ........................................................16

2.4 Formula editor....................................................................17

2.4.1 Overview ................................................................................... 17

2.4.2 Input field .................................................................................17

2.4.3 Arithmetic algorithms .............................................................. 18

2.4.4 Variables...................................................................................20

Overview ................................................................................................... 20

Method variables ...................................................................................... 20

Command variables.................................................................................. 21

Result variables ........................................................................................ 27

Table of contents iii

Determination variables ........................................................................... 27

System variables ...................................................................................... 28

Common variables.................................................................................... 28

2.4.5 Operators/Functions ................................................................ 29

Operators - Arithmetic.............................................................................. 30

Addition .............................................................................................. 30

Subtraction......................................................................................... 31

Multiplication ...................................................................................... 32

Division............................................................................................... 33

Potentiation ........................................................................................ 34

Operators - Logic...................................................................................... 35

AND .................................................................................................... 35

OR ...................................................................................................... 36

Operators - Compare................................................................................ 37

Equal .................................................................................................. 37

Larger than ......................................................................................... 38

Larger than or equal to....................................................................... 39

Smaller than ....................................................................................... 40

Smaller than or equal to..................................................................... 41

Unequal .............................................................................................. 42

Functions - Arithmetic .............................................................................. 43

Exponential function........................................................................... 43

Natural logarithm................................................................................ 43

Common logarithm ............................................................................ 43

Square root ........................................................................................ 44

Absolute value.................................................................................... 44

Fraction .............................................................................................. 44

Integer ................................................................................................ 45

Round integer..................................................................................... 45

Sign .................................................................................................... 46

Functions - Date/Time .............................................................................. 46

Time() ................................................................................................. 46

Time(Date).......................................................................................... 46

Time(Date + Time)............................................................................. 47

Functions - Type conversion.................................................................... 48

NumberToText ................................................................................... 48

NumberToTime .................................................................................. 48

TextToNumber.................................................................................... 49

TextToTime......................................................................................... 49

TimeToNumber .................................................................................. 50

TimeToText......................................................................................... 51

Functions - Text ........................................................................................ 52

TextPosition........................................................................................ 52

SubText .............................................................................................. 53

Trim .................................................................................................... 54

Miscellaneous functions .......................................................................... 54

Case ................................................................................................... 54

Error.................................................................................................... 55

ASCII table ................................................................................................ 56

2.5 Edit 57

2.5.1 Text editor ................................................................................ 57

2.5.2 Select date ............................................................................... 58

2.6 Manual control .................................................................. 59

2.6.1 General..................................................................................... 59

iv Table of contents

Select device ............................................................................ 60

2.6.2

2.6.3 Functions .................................................................................. 60

2.6.4 Graphic display ........................................................................60

2.6.5 Dosing .......................................................................................60

General...................................................................................................... 61

Prepare...................................................................................................... 62

Fill .............................................................................................................. 63

Empty ........................................................................................................ 64

Add fixed volume...................................................................................... 65

Dosing ....................................................................................................... 67

2.6.6 Stirring ......................................................................................68

Switch on/off ............................................................................................. 69

Continuous operation............................................................................... 70

2.6.7 Remote functions ..................................................................... 71

2.6.8 Sample changer functions....................................................... 72

General...................................................................................................... 73

Move .......................................................................................................... 74

Assign position ......................................................................................... 76

Pump ......................................................................................................... 78

Heater/Gas ................................................................................................ 79

Chapter 3 Workplace ................................... 81

3.1 General ...............................................................................81

3.1.1 General ..................................................................................... 81

3.1.2 Desktop..................................................................................... 81

3.1.3 Menu bar...................................................................................81

Menu File................................................................................................... 82

Menu View................................................................................................. 82

Menu Tools ............................................................................................... 82

Menu Help ................................................................................................. 83

3.1.4 Toolbar......................................................................................83

3.1.5 Subwindows .............................................................................84

3.1.6 Functions .................................................................................. 84

3.1.7 Workplace views ......................................................................86

Change layout........................................................................................... 87

Save view .................................................................................................. 88

Load view .................................................................................................. 89

Rename view............................................................................................. 89

Delete view................................................................................................ 89

3.2 Workplaces.........................................................................90

3.2.1 Create new workplace.............................................................90

3.2.2 Edit workplace .........................................................................90

3.2.3 Show workplace.......................................................................91

Select workplace in workplace symbol................................................... 91

Show single workplace ............................................................................ 91

Show workplaces beside each other ...................................................... 91

Show workplaces one below the other ................................................... 91

Table of contents v

Close workplace ...................................................................... 91

3.2.4

3.3 Sample tables.................................................................... 92

3.3.1 Edit ........................................................................................... 92

Create new sample table.......................................................................... 92

Open sample table.................................................................................... 92

Edit sample table ...................................................................................... 93

Edit sample data ....................................................................................... 94

Import sample data................................................................................... 96

Save sample table .................................................................................... 96

Print sample table (PDF) .......................................................................... 97

3.3.2 Properties................................................................................. 98

Display................................................................................................ 98

Edit ..................................................................................................... 99

Process............................................................................................. 100

Data import....................................................................................... 101

Comment.......................................................................................... 103

3.3.3 Manager ................................................................................. 103

Sample table manager ........................................................................... 103

Rename sample table............................................................................. 104

Copy sample table.................................................................................. 104

Delete sample table................................................................................ 104

Export sample table................................................................................ 104

Import sample table................................................................................ 104

3.4 Tools 105

3.4.1 Run test .................................................................................. 105

3.4.2 Sample assignment table...................................................... 105

General.................................................................................................... 105

Sample assignment table....................................................................... 106

Sample assignment ................................................................................ 106

Sample assignment request .................................................................. 107

3.4.3 Text templates ....................................................................... 107

3.5 Subwindow Run............................................................... 109

3.5.1 General................................................................................... 109

3.5.2 Single determination ............................................................. 109

Overview.................................................................................................. 109

Operating tools ....................................................................................... 110

Status display ......................................................................................... 110

Determination parameters ..................................................................... 111

Modify remark .................................................................................. 111

Sample data ............................................................................................ 112

Live modifications .................................................................................. 113

Modification comment for sample data................................................. 114

Determination run................................................................................... 114

Properties................................................................................................ 117

Display.............................................................................................. 117

Process............................................................................................. 118

Data import....................................................................................... 119

3.5.3 Determination series ............................................................. 120

Overview.................................................................................................. 120

Operating tools ....................................................................................... 120

Status display ......................................................................................... 121

vi Table of contents

Determination parameters ..................................................................... 122

Modify remark ...................................................................................123

Modify autostart counter...................................................................123

Sample data ............................................................................................ 123

Determination run................................................................................... 124

Working sample table............................................................................. 127

Load new and empty sample table ..................................................127

Load sample table ............................................................................127

Edit working sample table ................................................................128

Edit sample data ...............................................................................130

Import sample data...........................................................................132

Save sample table.............................................................................132

3.5.4 Run test ..................................................................................133

Print sample table (PDF)...................................................................133

Properties................................................................................................ 134

Display ..............................................................................................134

Edit ....................................................................................................136

Process .............................................................................................137

Data import .......................................................................................138

Comment ..........................................................................................139

3.6 Subwindow Method..........................................................140

3.6.1 General ................................................................................... 140

3.6.2 Zoom for method window ......................................................140

3.6.3 Live modifications ..................................................................140

3.6.4 Quit command ........................................................................ 141

3.7 Subwindow Live display ..................................................142

3.7.1 General ................................................................................... 142

3.7.2 Tracks .....................................................................................142

3.7.3 Application note .....................................................................143

3.7.4 Properties ...............................................................................143

3.8 Subwindow Report ...........................................................146

3.8.1 General ................................................................................... 146

3.8.2 Latest report........................................................................... 146

3.8.3 Selected report.......................................................................146

3.8.4 Report overview .....................................................................146

Chapter 4 Database ................................... 149

4.1 General .............................................................................149

4.1.1 General ................................................................................... 149

4.1.2 Desktop................................................................................... 149

4.1.3 Menu bar.................................................................................150

Menu File................................................................................................. 150

Menu Edit ................................................................................................ 150

Menu View............................................................................................... 150

Menu Determinations ............................................................................. 151

Menu Tools ............................................................................................. 152

Menu Help ............................................................................................... 152

Table of contents vii

Toolbar ................................................................................... 153

4.1.4

4.1.5 Subwindows ........................................................................... 154

4.1.6 Functions................................................................................ 155

4.1.7 Database views...................................................................... 155

Change layout......................................................................................... 156

Save view ................................................................................................ 156

Load view ................................................................................................ 157

Rename view........................................................................................... 158

Delete view.............................................................................................. 158

4.2 Open/display database ................................................... 159

4.2.1 Open database....................................................................... 159

4.2.2 Select database in database symbol.................................... 160

4.2.3 Show single database ........................................................... 160

4.2.4 Show databases beside each other...................................... 160

4.2.5 Show databases one below the other .................................. 160

4.2.6 Close database ...................................................................... 161

4.3 Manage databases.......................................................... 162

4.3.1 Database manager ................................................................ 162

4.3.2 Create new database ............................................................ 163

4.3.3 Rename database.................................................................. 163

4.3.4 Delete database..................................................................... 163

4.3.5 Database properties .............................................................. 164

General............................................................................................. 164

Access rights.................................................................................... 165

Backup ............................................................................................. 165

Monitoring ........................................................................................ 166

4.3.6 Manual database backup ...................................................... 167

4.3.7 Restore database................................................................... 167

4.4 Report templates ............................................................ 169

4.4.1 Create new report template.................................................. 169

4.4.2 Open report template ............................................................ 169

4.4.3 Edit report templates............................................................. 170

General.................................................................................................... 170

Desktop ............................................................................................ 171

Menu bar .......................................................................................... 171

Menu File.....................................................................................172

Menu Edit ....................................................................................172

Menu View...................................................................................172

Menu Insert .................................................................................173

Menu Tools..................................................................................173

Menu Help...................................................................................173

General toolbar ................................................................................ 173

Module-specific toolbar.................................................................... 174

Module bar ....................................................................................... 174

Functions................................................................................................. 175

Page setup ....................................................................................... 175

viii Table of contents

Define sections..................................................................................176

Insert pages ......................................................................................177

Insert modules ..................................................................................177

Edit modules .....................................................................................178

Zoom for report templates ................................................................179

Page preview ....................................................................................179

Comment ..........................................................................................180

Options..............................................................................................181

Save report template.........................................................................181

Modules................................................................................................... 183

Text field............................................................................................183

Data field ...........................................................................................184

Date field ...........................................................................................185

Time field...........................................................................................186

Page number ....................................................................................187

Number of pages ..............................................................................188

Fixed report.......................................................................................189

Image ................................................................................................190

Line....................................................................................................191

Rectangle ..........................................................................................191

Curve field .........................................................................................192

Curve field - x axis ...................................................................... 193

Curve field - y1 axis .................................................................... 194

Curve field - y2 axis .................................................................... 196

Curve field - options ................................................................... 197

Calibration curve field .......................................................................199

4.4.4 Manage report templates ...................................................... 200

Rename report template ...................................................................200

Copy report templates ......................................................................201

Delete report templates ....................................................................201

Export report templates ....................................................................201

Import report template ......................................................................201

4.5 Templates for control chart.............................................202

4.5.1 Manage control chart templates...........................................202

4.5.2 Properties ...............................................................................202

Graphical settings .............................................................................203

Limits.................................................................................................204

Statistics............................................................................................204

Comment ..........................................................................................205

4.6 Templates for curve overlay ............................................206

4.6.1 Manage curve overlay templates ..........................................206

4.6.2 Properties ...............................................................................207

x Axis.................................................................................................207

y-axis .................................................................................................208

Options..............................................................................................209

Comment ..........................................................................................210

4.7 Export templates..............................................................211

4.7.1 Manage ...................................................................................211

4.7.2 Properties ...............................................................................212

Select fields.......................................................................................213

Options..............................................................................................214

Table of contents ix

4.8 Subwindow Determination overview.............................. 215

4.8.1 General................................................................................... 215

Overview.................................................................................................. 215

Determination table ................................................................................ 215

Column display....................................................................................... 216

Filter selection ........................................................................................ 217

Navigation bar......................................................................................... 217

Table navigation ..................................................................................... 218

Data record selection ............................................................................. 218

4.8.2 Functions................................................................................ 219

Overview.................................................................................................. 219

Update determination table.................................................................... 220

Determination comment......................................................................... 220

Search determinations ........................................................................... 220

Filter determinations .............................................................................. 222

Last filter ........................................................................................... 222

Quick filter ........................................................................................ 222

Special filter...................................................................................... 222

Edit filter criterion ........................................................................224

Save filter.......................................................................................... 226

All statistics records ....................................................................226

Remove filter .................................................................................... 226

Sign determinations ............................................................................... 227

Rules................................................................................................. 227

Sign determinations at Level 1......................................................... 228

Sign determinations at Level 2......................................................... 229

Show determination signatures ....................................................... 230

Delete signatures 2 for determinations ............................................ 230

Export determinations ............................................................................ 231

Import determinations ............................................................................ 231

Delete determinations ............................................................................ 231

Print determination overview ................................................................. 232

Print determination report...................................................................... 233

Show determination method.................................................................. 234

Show determination history ................................................................... 235

Show calibration curve................................................................235

Control chart ........................................................................................... 237

Overlay curves ........................................................................................ 239

4.8.3 Reprocess determinations .................................................... 240

General.................................................................................................... 240

Reprocessing window ............................................................................ 241

Reprocessing rules ................................................................................ 242

Modifications .......................................................................................... 243

Variables........................................................................................... 244

Method ............................................................................................. 245

Statistics ........................................................................................... 246

Curve evaluation............................................................................... 247

Edit curve ebvaluation............................................................................ 248

Properties ......................................................................................... 250

x axis............................................................................................250

y axis ...........................................................................................251

Options........................................................................................252

Result view.............................................................................................. 254

Results overview............................................................................... 254

Raw data .......................................................................................... 255

Modification comment for determinations............................................ 256

x Table of contents

4.9 Subwindow Information...................................................257

4.9.1 Overview ................................................................................. 257

4.9.2 Determination.........................................................................257

4.9.3 Method .................................................................................... 259

4.9.4 Sample ....................................................................................261

4.9.5 Configuration.......................................................................... 262

4.9.6 Messages................................................................................264

4.9.7 Determination comment ........................................................264

4.10 Subwindow Results..........................................................265

4.10.1 Overview .................................................................................265

4.10.2 Results overview .................................................................... 265

4.10.3 Raw data................................................................................. 266

4.10.4 Calculation command ............................................................ 266

4.10.5 Properties ...............................................................................268

4.11 Subwindow Curves...........................................................269

4.11.1 General ...................................................................................269

4.11.2 Measuring point list ...............................................................270

4.11.3 Monitoring report ...................................................................271

4.11.4 Properties ...............................................................................272

x Axis.................................................................................................272

y1-axis ...............................................................................................273

y2 Axis...............................................................................................275

Options..............................................................................................276

Measuring point list...........................................................................278

Chapter 5 Method....................................... 281

5.1 General .............................................................................281

5.1.1 General ................................................................................... 281

5.1.2 Desktop................................................................................... 282

5.1.3 Menu bar.................................................................................282

Menu File................................................................................................. 282

Menu Edit ................................................................................................ 283

Menu View............................................................................................... 283

Menu Insert ............................................................................................. 284

Menu Tools ............................................................................................. 284

Menu Help ............................................................................................... 284

5.1.4 Toolbar....................................................................................284

5.1.5 Functions ................................................................................ 286

5.2 Method editor ...................................................................287

5.2.1 Create new method................................................................ 287

5.2.2 Open method ..........................................................................287

5.2.3 Display method.......................................................................289

Table of contents xi

Selecting the method in the method symbol ........................................ 289

Display single method............................................................................ 289

Display methods beside each other...................................................... 289

Display methods one below the other................................................... 289

Zoom for methods .................................................................................. 290

5.2.4 Edit method ............................................................................ 290

Edit tracks ............................................................................................... 290

Insert new track................................................................................ 290

Select track..................................................................................291

Move track........................................................................................ 291

Copy track........................................................................................ 291

Cut track........................................................................................... 292

Insert track........................................................................................ 292

Delete track ...................................................................................... 292

Edit commands ....................................................................................... 292

Insert new command........................................................................ 292

Select commands ............................................................................ 293

Move commands.............................................................................. 293

Copy commands.............................................................................. 293

Cut commands................................................................................. 293

Insert commands ............................................................................. 294

Delete commands ............................................................................ 294

Command properties ....................................................................... 294

Command comment ........................................................................ 294

5.2.5 Check method ........................................................................ 296

5.2.6 Save method .......................................................................... 296

5.2.7 Comment on modification for method .................................. 298

5.2.8 Close method ......................................................................... 298

5.3 Manage methods............................................................. 299

5.3.1 Manage methods ................................................................... 299

5.3.2 Rename method..................................................................... 300

5.3.3 Copy method .......................................................................... 301

5.3.4 Move method.......................................................................... 301

5.3.5 Delete method........................................................................ 301

5.3.6 Export method........................................................................ 301

5.3.7 Import method ....................................................................... 302

5.3.8 Sign methods ......................................................................... 302

Rules........................................................................................................ 302

Sign method at level 1............................................................................ 303

Sign method at level 2............................................................................ 304

Show method signatures ....................................................................... 304

Delete signatures 2................................................................................. 305

5.3.9 Show method history ............................................................. 306

5.4 Manage method groups .................................................. 307

5.4.1 Manage method groups......................................................... 307

5.4.2 Method group properties ....................................................... 307

General.................................................................................................... 308

Access rights .......................................................................................... 308

xii Table of contents

5.5 Tracks...............................................................................309

5.5.1 General ................................................................................... 309

5.5.2 Track types.............................................................................310

Main track................................................................................................ 310

Normal track ........................................................................................... 310

Series start track .................................................................................... 311

Series end track...................................................................................... 312

Exit track ................................................................................................. 312

Error track ............................................................................................... 313

5.5.3 Edit tracks .............................................................................. 314

5.6 Commands .......................................................................315

5.6.1 General ................................................................................... 315

5.6.2 Edit commands.......................................................................316

5.6.3 Method command overview...................................................316

5.6.4 Track commands....................................................................318

START...................................................................................................... 319

General ....................................................................................... 319

Application note ......................................................................... 321

Method variables (table) ............................................................ 322

Method variables (properties).................................................... 323

TRACK..................................................................................................... 325

SERIES START........................................................................................ 326

SERIES END............................................................................................ 326

EXIT ......................................................................................................... 327

ERROR .................................................................................................... 327

END.......................................................................................................... 327

5.6.5 Titration commands...............................................................328

DET .......................................................................................................... 328

DET pH..............................................................................................331

General/Hardware ...................................................................... 332

Start conditions .......................................................................... 335

Titration parameters ................................................................... 337

Stop conditions .......................................................................... 339

Potentiometric evaluation........................................................... 340

Additional evaluations ................................................................ 344

Additional measured values....................................................... 348

DET U................................................................................................350

General/Hardware ...................................................................... 351

Start conditions .......................................................................... 353

Titration parameters ................................................................... 355

Stop conditions .......................................................................... 355

Potentiometric evaluation........................................................... 356

Additional evaluations ................................................................ 358

Additional measured values....................................................... 360

DET Ipol ............................................................................................360

General/Hardware ...................................................................... 361

Start conditions .......................................................................... 364

Titration parameters ................................................................... 364

Stop conditions .......................................................................... 364

Potentiometric evaluation........................................................... 364

Additional evaluations ................................................................ 365

Additional measured values....................................................... 368

Table of contents xiii

DET Upol .......................................................................................... 369

General/Hardware.......................................................................370

Start conditions ...........................................................................372

Titration parameters ....................................................................374

Stop conditions ...........................................................................376

Potentiometric evaluation............................................................377

Additional evaluations.................................................................379

Additional measured values .......................................................381

MET.......................................................................................................... 382

MET pH ............................................................................................ 383

General/Hardware.......................................................................384

Start conditions ...........................................................................384

Titration parameters ....................................................................384

Stop conditions ...........................................................................386

Potentiometric evaluation............................................................386

Additional evaluations.................................................................387

Additional measured values .......................................................387

MET U............................................................................................... 387

General/Hardware.......................................................................387

Start conditions ...........................................................................388

Titration parameters ....................................................................388

Stop conditions ...........................................................................388

Potentiometric evaluation............................................................388

Additional evaluations.................................................................388

Additional measured values .......................................................388

MET Ipol ........................................................................................... 388

General/Hardware.......................................................................389

Start conditions ...........................................................................389

Titration parameters ....................................................................389

Stop conditions ...........................................................................389

Potentiometric evaluation............................................................389

Additional evaluations.................................................................389

Additional measured values .......................................................389

MET Upol.......................................................................................... 390

General/Hardware.......................................................................390

Start conditions ...........................................................................390

Titration parameters ....................................................................390

Stop conditions ...........................................................................391

Potentiometric evaluation............................................................391

Additional evaluations.................................................................391

Additional measured values .......................................................391

SET .......................................................................................................... 392

SET pH ............................................................................................. 393

General/Hardware.......................................................................394

Start conditions ...........................................................................394

Control parameters .....................................................................397

Titration parameters ....................................................................399

Stop conditions ...........................................................................400

Conditioning................................................................................401

Additional evaluations.................................................................403

Additional measured values .......................................................404

SET U ............................................................................................... 405

General/Hardware.......................................................................405

Start conditions ...........................................................................405

Control parameters .....................................................................406

Titration parameters ....................................................................408

Stop conditions ...........................................................................408

xiv Table of contents

Conditioning ............................................................................... 408

Additional evaluations ................................................................ 409

Additional measured values....................................................... 410

SET Ipol.............................................................................................410

General/Hardware ...................................................................... 411

Start conditions .......................................................................... 411

Control parameters .................................................................... 411

Titration parameters ................................................................... 411

Stop conditions .......................................................................... 411

Conditioning ............................................................................... 411

Additional evaluations ................................................................ 411

Additional measured values....................................................... 411

SET Upol...........................................................................................412

General/Hardware ...................................................................... 412

Start conditions .......................................................................... 413

Control parameters .................................................................... 414

Titration parameters ................................................................... 416

Stop conditions .......................................................................... 416

Conditioning ............................................................................... 416

Additional evaluations ................................................................ 417

Additional measured values....................................................... 418

KFT .......................................................................................................... 419

KFT Ipol.............................................................................................421

General/Hardware ...................................................................... 421

Start conditions .......................................................................... 424

Control parameters .................................................................... 424

Titration parameters ................................................................... 426

Stop conditions .......................................................................... 427

Conditioning ............................................................................... 427

Additional evaluations ................................................................ 427

Additional measured values....................................................... 427

KFT Upol ...........................................................................................427

General/Hardware ...................................................................... 428

Start conditions .......................................................................... 428

Control parameters .................................................................... 428

Titration parameters ................................................................... 428

Stop conditions .......................................................................... 428

Conditioning ............................................................................... 428

Additional evaluations ................................................................ 428

Additional measured values....................................................... 428

KFC.......................................................................................................... 429

General/Hardware ...................................................................... 430

Start conditions .......................................................................... 431

Control parameters .................................................................... 432

Titration parameters ................................................................... 434

Stop conditions .......................................................................... 435

Conditioning ............................................................................... 435

Additional evaluations ................................................................ 438

Additional measured values....................................................... 438

STAT ........................................................................................................ 439

STAT pH............................................................................................ 440

General/Hardware ...................................................................... 441

Start conditions .......................................................................... 446

Control parameters .................................................................... 448

Titration parameters ................................................................... 450

Stop conditions .......................................................................... 451

Monitoring................................................................................... 452

Table of contents xv

Evaluations..................................................................................459

Additional measured values .......................................................462

STAT U ............................................................................................. 462

General/Hardware.......................................................................463

Start conditions ...........................................................................466

Control parameters .....................................................................467

Titration parameters ....................................................................469

Stop conditions ...........................................................................470

Monitoring ...................................................................................471

Evaluations..................................................................................477

Additional measured values .......................................................480

Evaluation................................................................................................ 480

pK value and half neutralization potential ........................................ 480

Minimum and maximum evaluation ................................................. 481

Break point evaluation...................................................................... 482

Gran evaluation ................................................................................ 483

5.6.6 Measuring commands ........................................................... 484

MEAS pH ................................................................................................. 484

General/Hardware.......................................................................485

Measuring parameters................................................................ 487

Evaluations..................................................................................489

Additional measured values .......................................................491

MEAS U ................................................................................................... 491

General/Hardware.......................................................................492

Measuring parameters................................................................ 493

Evaluations..................................................................................495

Additional measured values .......................................................497

MEAS Ipol................................................................................................ 497

General/Hardware.......................................................................498

Measuring parameters................................................................ 499

Evaluations..................................................................................499

Additional measured values .......................................................499

MEAS Upol .............................................................................................. 500

General/Hardware.......................................................................501

Measuring parameters................................................................ 502

Evaluations..................................................................................504

Additional measured values .......................................................506

MEAS T.................................................................................................... 506

General/Hardware.......................................................................507

Measuring parameters................................................................ 508

Evaluations..................................................................................510

Additional measured values .......................................................512

MEAS T/Flow........................................................................................... 512

General/Hardware.......................................................................512

Measuring parameters................................................................ 513

Evaluations..................................................................................513

Additional measured values .......................................................514

MEAS Conc ............................................................................................. 514

General/Hardware.......................................................................515

Measuring parameters................................................................ 516

Additional measured values .......................................................516

MEAS Cond............................................................................................. 516

General/Hardware.......................................................................517

Measuring parameters................................................................ 518

Evaluations..................................................................................519

Additional measured values .......................................................520

STDADD................................................................................................... 521

xvi Table of contents

STDADD man....................................................................................521

General/Hardware ...................................................................... 522

Standard addition....................................................................... 524

Measuring parameters ............................................................... 525

STDADD dos.....................................................................................527

General/Hardware ...................................................................... 528

Standard addition....................................................................... 530

Measuring parameters ............................................................... 531

STDADD auto....................................................................................531

General/Hardware ...................................................................... 532

Standard addition....................................................................... 532

Measuring parameters ............................................................... 533

5.6.7 Calibration commands...........................................................533

Calibrating with manual solution changing .......................................... 535

Calibrating with automatic solution changing ...................................... 536

CAL LOOP pH ......................................................................................... 537

CAL LOOP pH - properties ........................................................ 538

CAL MEAS pH ......................................................................................... 539

General/Hardware ...................................................................... 539

Measuring parameters ............................................................... 542

CAL LOOP Conc ..................................................................................... 543

CAL LOOP Conc - properties .................................................... 543

CAL MEAS Conc..................................................................................... 544

General/Hardware ...................................................................... 544

Measuring parameters ............................................................... 545

5.6.8 Dosing commands.................................................................. 546

ADD.......................................................................................................... 546

General/Hardware ...................................................................... 547

Dosing parameters..................................................................... 550

DOS ......................................................................................................... 551

DOS pH.............................................................................................551

General/Hardware ...................................................................... 552

Dosing parameters..................................................................... 554

Stop conditions .......................................................................... 556

Monitoring................................................................................... 557

Additional measured values....................................................... 560

DOS U ...............................................................................................560

General/Hardware ...................................................................... 561

Dosing parameters..................................................................... 564

Stop conditions .......................................................................... 564

Monitoring................................................................................... 565

Additionan measured values ..................................................... 569

LQH.......................................................................................................... 569

General/Hardware ...................................................................... 569

Parameters ................................................................................. 570

PREP........................................................................................................ 572

PREP - properties....................................................................... 573

EMPTY ..................................................................................................... 575

EMPTY - properties .................................................................... 575

5.6.9 Automation commands..........................................................576

MOVE....................................................................................................... 576

MOVE - properties...................................................................... 577

SWING ..................................................................................................... 579

SWING - properties .................................................................... 579

LIFT.......................................................................................................... 581

LIFT - Properties ......................................................................... 581

Table of contents xvii

PUMP....................................................................................................... 582

PUMP - properties.......................................................................583

STIR ......................................................................................................... 584

STIR - properties .........................................................................584

RACK ....................................................................................................... 586

RACK - properties .......................................................................586

HEATER................................................................................................... 587

HEATER - properties...................................................................588

FLOW....................................................................................................... 589

FLOW - properties.......................................................................590

5.6.10 Result commands .................................................................. 591

CALC ....................................................................................................... 591

CALC - result table ........................................................................... 592

CALC result properties..................................................................... 594

Result - definition ........................................................................594

Result - Monitoring......................................................................595

Result - options ...........................................................................597

Send e-mail .................................................................................598

Result templates............................................................................... 599

Manage result templates ............................................................599

Save result template ...................................................................599

Rename result template..............................................................600

DATABASE .............................................................................................. 600

DATABASE - properties ..............................................................601

REPORT................................................................................................... 602

REPORT - Properties ..................................................................602

EXPORT................................................................................................... 603

EXPORT - properties...................................................................603

5.6.11 Communication commands................................................... 604

CTRL........................................................................................................ 604

CTRL - Properties........................................................................605

SCAN ....................................................................................................... 606

SCAN - Properties.......................................................................606

SEND ....................................................................................................... 608

SEND - properties.......................................................................608

SEND - event messages.............................................................609

RECEIVE.................................................................................................. 610

RECEIVE - properties..................................................................610

RECEIVE - event/state ................................................................612

TRANSFER .............................................................................................. 613

TRANSFER - properties ..............................................................613

TRANSFER - transfer commands...............................................614

5.6.12 Miscellaneous commands ..................................................... 617

REQUEST ................................................................................................ 617

REQUEST - properties ................................................................617

REQUEST - sample data request...............................................619

CALL ........................................................................................................ 620

CALL - properties........................................................................620

CALL - call...................................................................................621

LOOP ....................................................................................................... 622

LOOP - properties.......................................................................624

WAIT ........................................................................................................ 625

WAIT - properties ........................................................................625

SEQUENCE ............................................................................................. 626

SEQUENCE - properties.............................................................627

xviii Table of contents

5.7 Method reports.................................................................628

5.7.1 Select method reports ...........................................................628

5.7.2 Method sequence report........................................................628

5.7.3 Method parameters report.....................................................629

5.7.4 Titration and measurement parameters report ...................629

Chapter 6 Configuration ............................ 631

6.1 General .............................................................................631

6.1.1 General ................................................................................... 631

6.1.2 Desktop................................................................................... 631

6.1.3 Menu bar.................................................................................632

Menu File................................................................................................. 632

Menu View............................................................................................... 632

Menu Tools ............................................................................................. 633

Menu Help ............................................................................................... 633

6.1.4 Toolbar....................................................................................634

6.1.5 Subwindows ...........................................................................634

6.1.6 Functions ................................................................................ 635

6.1.7 Configuration views ............................................................... 636

Change layout......................................................................................... 636

Save view ................................................................................................ 637

Load view ................................................................................................ 638

Rename view........................................................................................... 639

Delete view.............................................................................................. 639

6.2 Administration..................................................................640

6.2.1 Security settings ....................................................................640

Login/Password protection.................................................................... 641

Send e-mail ................................................................................ 643

Audit Trail/Modifications ........................................................................ 644

Signatures............................................................................................... 645

Default reasons....................................................................................... 646

6.2.2 User administration ............................................................... 648

User groups ............................................................................................ 649

User group information.....................................................................649

Access rights.....................................................................................651

Signatures.........................................................................................652

Options..............................................................................................653

Add user group .................................................................................653

Copy user group...............................................................................654

Rename user group ..........................................................................654

Delete user group .............................................................................654

Add user............................................................................................655

Users ....................................................................................................... 655

User information................................................................................655

Add user............................................................................................656

Set start password ............................................................................657

6.2.3 Program administration......................................................... 658

Backup directories ................................................................................. 658

Create new backup directory............................................................659

Table of contents xix

Edit backup directory ....................................................................... 659

Clients............................................................................................... 660

Licenses ........................................................................................... 660

6.3 Configuration data .......................................................... 662

6.3.1 Export/Import ......................................................................... 662

Export configuration data....................................................................... 662

Import configuration data....................................................................... 664

6.3.2 Backup/Restore...................................................................... 665

Backup configuration data automatically ............................................. 665

Backup configuration data manually..................................................... 666

Restore configuration data .................................................................... 668

6.3.3 Templates .............................................................................. 669

Custom calibration buffers .................................................................... 669

Templates for input lines........................................................................ 670

Templates for output lines ..................................................................... 671

6.3.4 Options ................................................................................... 673

General............................................................................................. 673

Save.................................................................................................. 674

PDF................................................................................................... 674

6.4 Audit Trail ........................................................................ 675

6.4.1 General................................................................................... 675

General.................................................................................................... 675

Desktop ................................................................................................... 675

Menu bar ................................................................................................. 675

Menu File.......................................................................................... 676

Menu View........................................................................................ 676

Menu Filter........................................................................................ 676

Menu Tools....................................................................................... 676

Menu Help........................................................................................ 676

Toolbar .................................................................................................... 677

Filter selection ........................................................................................ 677

Audit Trail - navigation bar..................................................................... 677

Functions................................................................................................. 678

6.4.2 Audit Trail table ..................................................................... 678

Column display....................................................................................... 680

Filter Audit Trail ...................................................................................... 680

Last filter ........................................................................................... 680

Quick filter ........................................................................................ 681

Special filter...................................................................................... 681

Edit filter condition ......................................................................683

Save filter.....................................................................................684

Remove filter .................................................................................... 684

Update Audit Trail................................................................................... 685

Export Audit Trail .................................................................................... 685

Archive Audit Trail .................................................................................. 685

Delete Audit Trail .................................................................................... 686

Print Audit Trail ....................................................................................... 687

Audit Trail monitoring............................................................................. 687

6.5 Subwindow Devices ........................................................ 688

6.5.1 General................................................................................... 688

6.5.2 Device table ........................................................................... 688

xx Table of contents

Column display....................................................................................... 690

Add new device ...................................................................................... 691

Delete device .......................................................................................... 691

Print devices list ..................................................................................... 691

6.5.3 Device properties ...................................................................692

Overview ................................................................................................. 692

Titrando ................................................................................................... 692

General..............................................................................................693

Load new program version ........................................................ 693

Measuring inputs ..............................................................................694

MSB #...............................................................................................695

GLP ...................................................................................................696

Titrino ...................................................................................................... 697

General..............................................................................................697

Load new program version ........................................................ 698

Int. dosing device D0 ........................................................................699

Ext. dosing device D# ......................................................................699

RS 232...............................................................................................700

GLP ...................................................................................................701

Coulometer ............................................................................................. 702

General..............................................................................................702

Load new program version ........................................................ 703

RS 232...............................................................................................703

GLP ...................................................................................................704

Conductometer ....................................................................................... 706

General..............................................................................................706

Load new program version ........................................................ 707

RS 232...............................................................................................707

GLP ...................................................................................................708

Dosing Interface ..................................................................................... 709

General..............................................................................................709

Load new program version ........................................................ 710

MSB #...............................................................................................711

GLP ...................................................................................................712

814/815 USB Sample Processor............................................................ 713

General..............................................................................................714

Load new program version ........................................................ 714

Tower #.............................................................................................715

Robotic arm configuration.......................................................... 716

External position......................................................................... 718

Rack ..................................................................................................719

MSB #...............................................................................................720

GLP ...................................................................................................721

855 Robotic Titrosampler....................................................................... 722

General..............................................................................................722

Load new program version ........................................................ 723

Measuring inputs ..............................................................................724

Tower #.............................................................................................725

External position......................................................................... 728

Rack ..................................................................................................728

MSB #...............................................................................................729

GLP ...................................................................................................730

778/789 Sample Processor .................................................................... 732

General..............................................................................................733

Load new program version ........................................................ 733

Tower #.............................................................................................734

Robotic arm configuration.......................................................... 736

Table of contents xxi

External position..........................................................................737

Rack ................................................................................................. 738

MSB # .............................................................................................. 739

RS 232.............................................................................................. 740

GLP................................................................................................... 740

730 Sample Changer .............................................................................. 741

General............................................................................................. 742

Load new program version.........................................................742

Towers.............................................................................................. 743

Rack ................................................................................................. 744

Dosing device................................................................................... 745

RS 232.............................................................................................. 745

GLP................................................................................................... 746

774 Oven Sample Processor ................................................................. 747

General............................................................................................. 748

Load new program version.........................................................748

Towers.............................................................................................. 749

Rack ................................................................................................. 750

Edit rack properties (774)................................................................. 751

Lift positions ................................................................................751

Special beakers ..........................................................................752

Dosing device................................................................................... 752

Oven ................................................................................................. 753

Gas ................................................................................................... 753

RS 232.............................................................................................. 754

GLP................................................................................................... 755

Balance.................................................................................................... 756

General............................................................................................. 756

RS 232.............................................................................................. 757

Test connection...........................................................................758

GLP................................................................................................... 759

Barcode reader ....................................................................................... 760

General............................................................................................. 760

Settings ............................................................................................ 761

Check connection .......................................................................762

GLP................................................................................................... 762

RS232 device .......................................................................................... 763

General............................................................................................. 764

RS 232.............................................................................................. 765

Test connection...........................................................................766

GLP................................................................................................... 766

6.6 Subwindow Titrants/Solutions........................................ 768

6.6.1 General................................................................................... 768

6.6.2 Solution table......................................................................... 768

Column display....................................................................................... 770

Add new solution .................................................................................... 770

Delete solution........................................................................................ 771

Print solution list..................................................................................... 771

6.6.3 Solution properties ................................................................ 771

Solution ............................................................................................ 772

Titer................................................................................................... 773

Titer history....................................................................................... 775

Titer history - Limits .....................................................................776

Exchange unit .................................................................................. 777

Dosing unit ....................................................................................... 780

xxii Table of contents

GLP ...................................................................................................784

6.7 Subwindow Sensors.........................................................786

6.7.1 General ................................................................................... 786

6.7.2 Sensor table ...........................................................................786

Column display....................................................................................... 788

Add new sensor...................................................................................... 788

Delete sensor.......................................................................................... 789

Print sensor list....................................................................................... 789

6.7.3 Sensor properties...................................................................790

Edit properties ............................................................................ 790

Sensor...............................................................................................790

Calibration data.................................................................................792

Limits.................................................................................................794

History ..................................................................................................... 795

Sensor history - Limits................................................................ 796

6.8 Subwindow Common Variables.......................................799

6.8.1 General ................................................................................... 799

6.8.2 Table of common variables ...................................................799

Column display....................................................................................... 801

Add new common variable..................................................................... 801

Delete common variable ........................................................................ 802

Print list of common variables ............................................................... 802

6.8.3 Common variables properties ...............................................802

Common variable..............................................................................803

History...............................................................................................805

History - limits............................................................................. 806

6.9 Subwindow Rack data .....................................................807

6.9.1 General ................................................................................... 807

6.9.2 Rack table ..............................................................................807

Add new rack .......................................................................................... 808

Delete rack .............................................................................................. 809

Print rack list........................................................................................... 809

6.9.3 Rack properties......................................................................810

Rack parameters...............................................................................811

Lift positions......................................................................................812

Special beakers ................................................................................813

Special beaker............................................................................ 814

Chapter 7 How to proceed......................... 815

7.1 Audit Trail .........................................................................815

7.1.1 Open Audit Trail......................................................................815

7.1.2 Filter Audit Trail .....................................................................815

7.1.3 Export Audit Trail ...................................................................816

7.1.4 Archive Audit Trail.................................................................. 816

7.1.5 Delete Audit Trail ...................................................................817

7.2 Backup..............................................................................818

Table of contents xxiii

Backup database................................................................... 818

7.2.1

7.2.2 Restore database................................................................... 819

7.2.3 Backup configuration data.................................................... 819

7.2.4 Restore configuration data ................................................... 820

7.2.5 Backup methods .................................................................... 821

7.2.6 Archive Audit Trail ................................................................. 822

7.3 Determinations................................................................ 823

7.3.1 Start single determination .................................................... 823

7.3.2 Start determination series .................................................... 824

7.3.3 Search determinations .......................................................... 825

7.3.4 Filter determinations ............................................................. 825

7.3.5 Sign determination ................................................................ 826

7.3.6 Export determinations ........................................................... 827

7.3.7 Import determinations........................................................... 827

7.3.8 Delete determinations........................................................... 828

7.3.9 Make current previous determination version ..................... 828

7.3.10 Reprocess determinations .................................................... 828

7.3.11 Print determination report .................................................... 831

7.3.12 Print determination overview................................................ 831

7.4 Databases........................................................................ 832

7.4.1 Open database....................................................................... 832

7.4.2 Close database ...................................................................... 832

7.4.3 Create new database ............................................................ 832

7.4.4 Backup database................................................................... 833

7.4.5 Restore database................................................................... 834

7.4.6 Delete database..................................................................... 834

7.5 Configuration data .......................................................... 835

7.5.1 Export configuration data...................................................... 835

7.5.2 Import configuration data ..................................................... 835

7.5.3 Backup configuration data.................................................... 835

7.5.4 Restore configuration data ................................................... 836

7.6 Methods ........................................................................... 838

7.6.1 Open method.......................................................................... 838

7.6.2 Close method ......................................................................... 838

7.6.3 Create new method ............................................................... 838

7.6.4 Save method .......................................................................... 839

7.6.5 Delete method........................................................................ 839

7.6.6 Export method........................................................................ 840

xxiv Table of contents

Import method........................................................................840

7.6.7

7.6.8 Sign method............................................................................840

7.6.9 Make current previous method version ................................ 841

7.6.10 Print method report................................................................842

7.7 Method groups .................................................................843

7.7.1 Create new method group .....................................................843

7.7.2 Delete method group..............................................................843

7.8 Reports .............................................................................844

7.8.1 Create new report template ..................................................844

7.8.2 Edit report template...............................................................844

7.8.3 Print determination report..................................................... 845

7.8.4 Print method report................................................................846

7.8.5 Print determination overview ................................................ 846

7.9 Sample tables ..................................................................847

7.9.1 Create new sample table.......................................................847

7.9.2 Edit sample table ................................................................... 847

7.9.3 Load working sample table ................................................... 848

7.9.4 Edit working sample table.....................................................848

Chapter 8 Index.......................................... 849

Table of contents xxv

Chapter 1 Introduction

1.1 Welcome to tiamo

tiamo = titration and more

tiamo is a control and database software for titrators, dosing devices and sample
changers that allows complete laboratory automation, which is why the name

tiamo stands for «titration and more» – tiamo can do far more than just titrate.

tiamo is the successor of the TiNet and Workcell software. With it Metrohm now of-

fers worldwide a uniform software product for laboratory automation. This means
that an internationally operating concern can now use the same software platform
for processing all its samples and exchange data and methods without any loss.

The most important program features

• Easy to use and configurable user interface

• Easy integration of instruments and accessories

• Comfortable method editor

• Database program with client/server functionality

• Manifold import and export possibilities

• FDA compatibility according to 21 CFR Part 11

• Program versions

• Extensive online help

• What's new in tiamo 1.3?

Welcome to tiamo 1

1.2 User interface

The modern user interface makes it easy for users to familiarize themselves with
tiamo quickly. All command and control functions are located where users would
expect them. The tiamo bar on the left-hand side of the screen allows access to
the four basic tiamo components:

Whether these buttons are visible or concealed depends on the user’s rights of
access. The menu bar is located in the upper part of the screen. Again, each indi­vidual command can be concealed in accordance with the rights of access of the
user.

In the center of the screen are the information windows, in which settings, sam­ple input templates, real-time curves or results are shown. This display can be ad­justed individually for each user with the aid of the new Layout Manager. This
means that each user can only see the windows or buttons necessary for his or
her work. This shortens the familiarization time for users carrying out routine work
to a minimum; operating errors resulting from a cluttered screen are now a thing
of the past.

The methods and calculation templates successfully introduced with the Ti­trando system are also available with tiamo. Numerous tried and tested methods
allow users to draw up their own individual methods quickly and simply and to use
them immediately.

2 Introduction

1.3 Integration of devices

tiamo brings together the world of Titrino devices with the new generation of the
Titrando system. In the software sector such compatibility with existing Metrohm

devices is not just a matter of course. The whole Titrino family, which was previ­ously also controlled by TiNet, can continue to be operated under tiamo, and this
after more than 10 years on the market! In addition, sample changers, some of
which are no longer in our sales program, can also be operated under tiamo.
That's how Metrohm protects your investments!

Of course, all the models of the latest Titrando generation as well as the new
Sample Processors are compatible with tiamo. In this way all the advantages of
USB communication, such as plug and play or recognition of the intelligent dosing
systems, can be utilized to the full with tiamo. Even the mixed operation of older
RS 232-controlled and the new USB-controlled instruments is possible without any
problems.

Devices compatible with tiamo

• Titrando

808, 809, 835, 836, 841, 842, 855, 857, 888, 890

• Titrino

702, 716, 718, 719, 720, 721, 736, 751, 758, 784, 785, 794, 795, 798, 799

• Conductometer

712

• KF Coulometer

756, 831

• Sample Changer

730, 774, 778, 789, 814, 815, 855

• Miscellaneous

846 Dosing Interface, balances, barcode readers ...

Integration of devices 3

1.4 Method editor

The new graphical Method Editor makes more of your titration system. Methods
can be drawn up quickly and simply by using the numerous templates. Methods
that have been proved in practice are available for most routine and automation
tasks. A few clicks are all that is needed to adapt them and make them ready for
use.

It is now possible to program and link activities that take place in parallel. This
means that, together with the new Titrando system and the Robotic Sample Proc­essors, a sample can now be titrated while the next sample is already being pre­pared. This saves time and increases sample throughput. The crowning achieve­ment is the simultaneous processing of several samples – one Titrando can carry
out two titrations at the same time. This doubles sample throughput!

tiamo is flexible and adapts itself to the analytical sequence, not vice versa.

Overview of functions

• Graphical method editor

• Method manager

• Access rights management for each method group

• Templates for method development and calculations

• Method test

• Comments for methods

• Parallel track function

• Loop function

4 Introduction